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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for GCFC2 |
 Gene summary |
| Gene information | Gene symbol | GCFC2 | Gene ID | 6936 |
| Gene name | GC-rich sequence DNA-binding factor 2 | |
| Synonyms | C2orf3|DNABF|GCF|TCF9 | |
| Cytomap | 2p12 | |
| Type of gene | protein-coding | |
| Description | GC-rich sequence DNA-binding factor 2GC binding factorGC bindng factorTCF-9transcription factor 9 (binds GC-rich sequences) | |
| Modification date | 20200320 | |
| UniProtAcc | P16383, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| GCFC2 | GO:0000122 | negative regulation of transcription by RNA polymerase II | 9705290 |
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RNA A-to-I events for GCFC2 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_900446(75698749, -), ADediting_900447(75698761, -), ADediting_900448(75698769, -), ADediting_900449(75698776, -), ADediting_900450(75698777, -), ADediting_900451(75698849, -), ADediting_900452(75698884, -), ADediting_900453(75698890, -), ADediting_900454(75698900, -), ADediting_900455(75698912, -), ADediting_900456(75698926, -), ADediting_900457(75698929, -), ADediting_900458(75698936, -), ADediting_900459(75698968, -), ADediting_900460(75699668, -), ADediting_900461(75699678, -), ADediting_900462(75699716, -), ADediting_900463(75699755, -), ADediting_900464(75699756, -), ADediting_900465(75699759, -), ADediting_900466(75699776, -), ADediting_900467(75699780, -), ADediting_900468(75699795, -), ADediting_900469(75699814, -), ADediting_900470(75699856, -), ADediting_900471(75699969, -), ADediting_900472(75699984, -), ADediting_900473(75700015, -), ADediting_900474(75700016, -), ADediting_900475(75700039, -), ADediting_900476(75700070, -), ADediting_900477(75700071, -), ADediting_900478(75700074, -), ADediting_900479(75700076, -), ADediting_900480(75700078, -), ADediting_900481(75700080, -), ADediting_900482(75700100, -), ADediting_900483(75704715, -), ADediting_900484(75704718, -), ADediting_900485(75704720, -), ADediting_900486(75704723, -), ADediting_900487(75704742, -), ADediting_900488(75704747, -), ADediting_900489(75704770, -), ADediting_900490(75704781, -), ADediting_900491(75704782, -), ADediting_900492(75704793, -), ADediting_900493(75704794, -), ADediting_900494(75704795, -), ADediting_900495(75704809, -), ADediting_900496(75704832, -), ADediting_900497(75704840, -), ADediting_900498(75704843, -), ADediting_900499(75704851, -), ADediting_900500(75704852, -), ADediting_900501(75704853, -), ADediting_900502(75704854, -), ADediting_900503(75704855, -), ADediting_900504(75704858, -), ADediting_900505(75704869, -), ADediting_900506(75704878, -), ADediting_900507(75704879, -), ADediting_900508(75704880, -), ADediting_900509(75704888, -), ADediting_900510(75704889, -), ADediting_900511(75704892, -), ADediting_900512(75704894, -), ADediting_900513(75704903, -), ADediting_900514(75704979, -), ADediting_900515(75705429, -), ADediting_900516(75705430, -), ADediting_900517(75705434, -), ADediting_900518(75705456, -), ADediting_900519(75705459, -), ADediting_900520(75705475, -), ADediting_900521(75705530, -), ADediting_900522(75705541, -), ADediting_900523(75705554, -), ADediting_900524(75705570, -), ADediting_900525(75705571, -), ADediting_900526(75705603, -), ADediting_1564594(75704790, -), ADediting_1564595(75704796, -), ADediting_1564596(75704870, -), ADediting_1564597(75704955, -), ADediting_1639294(75700045, -), ADediting_1639295(75704908, -), ADediting_1639296(75705560, -), |
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RNA editing positional annotations for GCFC2 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_900446 | chr2_75698749_- | intronic |
| ADediting_900447 | chr2_75698761_- | intronic |
| ADediting_900448 | chr2_75698769_- | intronic |
| ADediting_900449 | chr2_75698776_- | intronic |
| ADediting_900450 | chr2_75698777_- | intronic |
| ADediting_900451 | chr2_75698849_- | intronic |
| ADediting_900452 | chr2_75698884_- | intronic |
| ADediting_900453 | chr2_75698890_- | intronic |
| ADediting_900454 | chr2_75698900_- | intronic |
| ADediting_900455 | chr2_75698912_- | intronic |
| ADediting_900456 | chr2_75698926_- | intronic |
| ADediting_900457 | chr2_75698929_- | intronic |
| ADediting_900458 | chr2_75698936_- | intronic |
| ADediting_900459 | chr2_75698968_- | intronic |
| ADediting_900460 | chr2_75699668_- | intronic |
| ADediting_900461 | chr2_75699678_- | intronic |
| ADediting_900462 | chr2_75699716_- | intronic |
| ADediting_900463 | chr2_75699755_- | intronic |
| ADediting_900464 | chr2_75699756_- | intronic |
| ADediting_900465 | chr2_75699759_- | intronic |
| ADediting_900466 | chr2_75699776_- | intronic |
| ADediting_900467 | chr2_75699780_- | intronic |
| ADediting_900468 | chr2_75699795_- | intronic |
| ADediting_900469 | chr2_75699814_- | intronic |
| ADediting_900470 | chr2_75699856_- | intronic |
| ADediting_900471 | chr2_75699969_- | intronic |
| ADediting_900472 | chr2_75699984_- | intronic |
| ADediting_900473 | chr2_75700015_- | intronic |
| ADediting_900474 | chr2_75700016_- | intronic |
| ADediting_900475 | chr2_75700039_- | intronic |
| ADediting_900476 | chr2_75700070_- | intronic |
| ADediting_900477 | chr2_75700071_- | intronic |
| ADediting_900478 | chr2_75700074_- | intronic |
| ADediting_900479 | chr2_75700076_- | intronic |
| ADediting_900480 | chr2_75700078_- | intronic |
| ADediting_900481 | chr2_75700080_- | intronic |
| ADediting_900482 | chr2_75700100_- | intronic |
| ADediting_900483 | chr2_75704715_- | intronic |
| ADediting_900484 | chr2_75704718_- | intronic |
| ADediting_900485 | chr2_75704720_- | intronic |
| ADediting_900486 | chr2_75704723_- | intronic |
| ADediting_900487 | chr2_75704742_- | intronic |
| ADediting_900488 | chr2_75704747_- | intronic |
| ADediting_900489 | chr2_75704770_- | intronic |
| ADediting_900490 | chr2_75704781_- | intronic |
| ADediting_900491 | chr2_75704782_- | intronic |
| ADediting_900492 | chr2_75704793_- | intronic |
| ADediting_900493 | chr2_75704794_- | intronic |
| ADediting_900494 | chr2_75704795_- | intronic |
| ADediting_900495 | chr2_75704809_- | intronic |
| ADediting_900496 | chr2_75704832_- | intronic |
| ADediting_900497 | chr2_75704840_- | intronic |
| ADediting_900498 | chr2_75704843_- | intronic |
| ADediting_900499 | chr2_75704851_- | intronic |
| ADediting_900500 | chr2_75704852_- | intronic |
| ADediting_900501 | chr2_75704853_- | intronic |
| ADediting_900502 | chr2_75704854_- | intronic |
| ADediting_900503 | chr2_75704855_- | intronic |
| ADediting_900504 | chr2_75704858_- | intronic |
| ADediting_900505 | chr2_75704869_- | intronic |
| ADediting_900506 | chr2_75704878_- | intronic |
| ADediting_900507 | chr2_75704879_- | intronic |
| ADediting_900508 | chr2_75704880_- | intronic |
| ADediting_900509 | chr2_75704888_- | intronic |
| ADediting_900510 | chr2_75704889_- | intronic |
| ADediting_900511 | chr2_75704892_- | intronic |
| ADediting_900512 | chr2_75704894_- | intronic |
| ADediting_900513 | chr2_75704903_- | intronic |
| ADediting_900514 | chr2_75704979_- | intronic |
| ADediting_900515 | chr2_75705429_- | intronic |
| ADediting_900516 | chr2_75705430_- | intronic |
| ADediting_900517 | chr2_75705434_- | intronic |
| ADediting_900518 | chr2_75705456_- | intronic |
| ADediting_900519 | chr2_75705459_- | intronic |
| ADediting_900520 | chr2_75705475_- | intronic |
| ADediting_900521 | chr2_75705530_- | intronic |
| ADediting_900522 | chr2_75705541_- | intronic |
| ADediting_900523 | chr2_75705554_- | intronic |
| ADediting_900524 | chr2_75705570_- | intronic |
| ADediting_900525 | chr2_75705571_- | intronic |
| ADediting_900526 | chr2_75705603_- | intronic |
| ADediting_1564594 | chr2_75704790_- | intronic |
| ADediting_1564595 | chr2_75704796_- | intronic |
| ADediting_1564596 | chr2_75704870_- | intronic |
| ADediting_1564597 | chr2_75704955_- | intronic |
| ADediting_1639294 | chr2_75700045_- | intronic |
| ADediting_1639295 | chr2_75704908_- | intronic |
| ADediting_1639296 | chr2_75705560_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_900446 | chr2_75698749_- | SINE | Alu | Name=AluSx3 |
| ADediting_900447 | chr2_75698761_- | SINE | Alu | Name=AluSx3 |
| ADediting_900448 | chr2_75698769_- | SINE | Alu | Name=AluSx3 |
| ADediting_900449 | chr2_75698776_- | SINE | Alu | Name=AluSx3 |
| ADediting_900450 | chr2_75698777_- | SINE | Alu | Name=AluSx3 |
| ADediting_900451 | chr2_75698849_- | SINE | Alu | Name=AluSx3 |
| ADediting_900452 | chr2_75698884_- | SINE | Alu | Name=AluSx3 |
| ADediting_900453 | chr2_75698890_- | SINE | Alu | Name=AluSx3 |
| ADediting_900454 | chr2_75698900_- | SINE | Alu | Name=AluSx3 |
| ADediting_900455 | chr2_75698912_- | SINE | Alu | Name=AluSx3 |
| ADediting_900456 | chr2_75698926_- | SINE | Alu | Name=AluSx3 |
| ADediting_900457 | chr2_75698929_- | SINE | Alu | Name=AluSx3 |
| ADediting_900458 | chr2_75698936_- | SINE | Alu | Name=AluSx3 |
| ADediting_900459 | chr2_75698968_- | SINE | Alu | Name=AluSx3 |
| ADediting_900460 | chr2_75699668_- | SINE | Alu | Name=AluJo |
| ADediting_900461 | chr2_75699678_- | SINE | Alu | Name=AluJo |
| ADediting_900462 | chr2_75699716_- | SINE | Alu | Name=AluJo |
| ADediting_900463 | chr2_75699755_- | SINE | Alu | Name=AluJo |
| ADediting_900464 | chr2_75699756_- | SINE | Alu | Name=AluJo |
| ADediting_900465 | chr2_75699759_- | SINE | Alu | Name=AluJo |
| ADediting_900466 | chr2_75699776_- | SINE | Alu | Name=AluJo |
| ADediting_900467 | chr2_75699780_- | SINE | Alu | Name=AluJo |
| ADediting_900468 | chr2_75699795_- | SINE | Alu | Name=AluJo |
| ADediting_900469 | chr2_75699814_- | SINE | Alu | Name=AluJo |
| ADediting_900470 | chr2_75699856_- | SINE | Alu | Name=AluJo |
| ADediting_900471 | chr2_75699969_- | SINE | Alu | Name=AluJb |
| ADediting_900472 | chr2_75699984_- | SINE | Alu | Name=AluJb |
| ADediting_900473 | chr2_75700015_- | SINE | Alu | Name=AluJb |
| ADediting_900474 | chr2_75700016_- | SINE | Alu | Name=AluJb |
| ADediting_900475 | chr2_75700039_- | SINE | Alu | Name=AluJb |
| ADediting_900476 | chr2_75700070_- | SINE | Alu | Name=AluJb |
| ADediting_900477 | chr2_75700071_- | SINE | Alu | Name=AluJb |
| ADediting_900478 | chr2_75700074_- | SINE | Alu | Name=AluJb |
| ADediting_900479 | chr2_75700076_- | SINE | Alu | Name=AluJb |
| ADediting_900480 | chr2_75700078_- | SINE | Alu | Name=AluJb |
| ADediting_900481 | chr2_75700080_- | SINE | Alu | Name=AluJb |
| ADediting_900482 | chr2_75700100_- | SINE | Alu | Name=AluJb |
| ADediting_900483 | chr2_75704715_- | SINE | Alu | Name=AluSx |
| ADediting_900484 | chr2_75704718_- | SINE | Alu | Name=AluSx |
| ADediting_900485 | chr2_75704720_- | SINE | Alu | Name=AluSx |
| ADediting_900486 | chr2_75704723_- | SINE | Alu | Name=AluSx |
| ADediting_900487 | chr2_75704742_- | SINE | Alu | Name=AluSx |
| ADediting_900488 | chr2_75704747_- | SINE | Alu | Name=AluSx |
| ADediting_900489 | chr2_75704770_- | SINE | Alu | Name=AluSx |
| ADediting_900490 | chr2_75704781_- | SINE | Alu | Name=AluSx |
| ADediting_900491 | chr2_75704782_- | SINE | Alu | Name=AluSx |
| ADediting_900492 | chr2_75704793_- | SINE | Alu | Name=AluSx |
| ADediting_900493 | chr2_75704794_- | SINE | Alu | Name=AluSx |
| ADediting_900494 | chr2_75704795_- | SINE | Alu | Name=AluSx |
| ADediting_900495 | chr2_75704809_- | SINE | Alu | Name=AluSx |
| ADediting_900496 | chr2_75704832_- | SINE | Alu | Name=AluSx |
| ADediting_900497 | chr2_75704840_- | SINE | Alu | Name=AluSx |
| ADediting_900498 | chr2_75704843_- | SINE | Alu | Name=AluSx |
| ADediting_900499 | chr2_75704851_- | SINE | Alu | Name=AluSx |
| ADediting_900500 | chr2_75704852_- | SINE | Alu | Name=AluSx |
| ADediting_900501 | chr2_75704853_- | SINE | Alu | Name=AluSx |
| ADediting_900502 | chr2_75704854_- | SINE | Alu | Name=AluSx |
| ADediting_900503 | chr2_75704855_- | SINE | Alu | Name=AluSx |
| ADediting_900504 | chr2_75704858_- | SINE | Alu | Name=AluSx |
| ADediting_900505 | chr2_75704869_- | SINE | Alu | Name=AluSx |
| ADediting_900506 | chr2_75704878_- | SINE | Alu | Name=AluSx |
| ADediting_900507 | chr2_75704879_- | SINE | Alu | Name=AluSx |
| ADediting_900508 | chr2_75704880_- | SINE | Alu | Name=AluSx |
| ADediting_900509 | chr2_75704888_- | SINE | Alu | Name=AluSx |
| ADediting_900510 | chr2_75704889_- | SINE | Alu | Name=AluSx |
| ADediting_900511 | chr2_75704892_- | SINE | Alu | Name=AluSx |
| ADediting_900512 | chr2_75704894_- | SINE | Alu | Name=AluSx |
| ADediting_900513 | chr2_75704903_- | SINE | Alu | Name=AluSx |
| ADediting_900515 | chr2_75705429_- | SINE | Alu | Name=AluY |
| ADediting_900516 | chr2_75705430_- | SINE | Alu | Name=AluY |
| ADediting_900517 | chr2_75705434_- | SINE | Alu | Name=AluY |
| ADediting_900518 | chr2_75705456_- | SINE | Alu | Name=AluY |
| ADediting_900519 | chr2_75705459_- | SINE | Alu | Name=AluY |
| ADediting_900520 | chr2_75705475_- | SINE | Alu | Name=AluY |
| ADediting_900521 | chr2_75705530_- | SINE | Alu | Name=AluY |
| ADediting_900522 | chr2_75705541_- | SINE | Alu | Name=AluY |
| ADediting_900523 | chr2_75705554_- | SINE | Alu | Name=AluY |
| ADediting_900524 | chr2_75705570_- | SINE | Alu | Name=AluY |
| ADediting_900525 | chr2_75705571_- | SINE | Alu | Name=AluY |
| ADediting_900526 | chr2_75705603_- | SINE | Alu | Name=AluY |
| ADediting_1564594 | chr2_75704790_- | SINE | Alu | Name=AluSx |
| ADediting_1564595 | chr2_75704796_- | SINE | Alu | Name=AluSx |
| ADediting_1564596 | chr2_75704870_- | SINE | Alu | Name=AluSx |
| ADediting_1564597 | chr2_75704955_- | SINE | Alu | Name=AluSx |
| ADediting_1639294 | chr2_75700045_- | SINE | Alu | Name=AluJb |
| ADediting_1639295 | chr2_75704908_- | SINE | Alu | Name=AluSx |
| ADediting_1639296 | chr2_75705560_- | SINE | Alu | Name=AluY |
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RNA A-to-I editing events in the alternative splicing sites for GCFC2 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for GCFC2 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for GCFC2 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for GCFC2 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000005436.14 | ENST00000470503.1 | GCFC2-207 | hsa-miR-381-3p | chr2 | 75701892 | 75701899 | 8mer-1a | 75701892 | 75701913 | 155 | -16.19 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1391023 | chr8_140732605_- | ENSG00000005436.14 | ENST00000321027.8 | GCFC2-201 | hsa-miR-151a-3p | chr2 | 75663633 | 75663639 | 7mer-m8 | 75663632 | 75663655 | 145 | -20.64 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000005436.14 | ENST00000541687.5 | GCFC2-211 | hsa-miR-151a-3p | chr2 | 75663633 | 75663639 | 7mer-m8 | 75663632 | 75663655 | 145 | -20.64 |
| ADediting_291761 | chr11_93733708_- | ENSG00000005436.14 | ENST00000321027.8 | GCFC2-201 | hsa-miR-1304-3p | chr2 | 75663151 | 75663157 | 7mer-m8 | 75663150 | 75663171 | 152 | -20.34 |
| ADediting_291761 | chr11_93733708_- | ENSG00000005436.14 | ENST00000541687.5 | GCFC2-211 | hsa-miR-1304-3p | chr2 | 75663151 | 75663157 | 7mer-m8 | 75663150 | 75663171 | 152 | -20.34 |
| ADediting_527135 | chr16_24203190_+ | ENSG00000005436.14 | ENST00000541687.5 | GCFC2-211 | hsa-miR-1273h-3p | chr2 | 75665955 | 75665961 | 7mer-m8 | 75665954 | 75665976 | 147 | -15.66 |
| ADediting_527135 | chr16_24203190_+ | ENSG00000005436.14 | ENST00000541687.5 | GCFC2-211 | hsa-miR-1273h-3p | chr2 | 75687860 | 75687867 | 8mer-1a | 75687860 | 75687881 | 151 | -14.54 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000005436.14 | ENST00000321027.8 | GCFC2-201 | hsa-miR-4775 | chr2 | 75663094 | 75663100 | 7mer-m8 | 75663093 | 75663115 | 148 | -3.11 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000005436.14 | ENST00000541687.5 | GCFC2-211 | hsa-miR-4775 | chr2 | 75663094 | 75663100 | 7mer-m8 | 75663093 | 75663115 | 148 | -3.11 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for GCFC2 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for GCFC2 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_900483 | chr2_75704715_- | 0.0568267085706736 | 0.108295498353929 | 0.468719187739992 | -0.0413017895037727 | 3.08711937286584e-10 | 0.347684374457864 |
| CER | ADediting_900483 | chr2_75704715_- | 0.000115673067788916 | 0.309589961012534 | 0.0155400208255269 | 0.197259879996979 | 0.365778956190318 | -0.0743644068621334 |
| STG | ADediting_900483 | chr2_75704715_- | 0.00471801665837666 | 0.30547813532736 | 0.0744726634162502 | 0.195663451386065 | 0.88206464885587 | -0.0164316960414755 |
| DLPFC | ADediting_900493 | chr2_75704794_- | 0.084765711694639 | 0.0980584898374306 | 0.313181383800002 | -0.0574676721799617 | 1.89209024628824e-12 | 0.385928490113399 |
| DLPFC | ADediting_900494 | chr2_75704795_- | 0.0662924973915421 | 0.10443932561082 | 0.296772362451935 | -0.0594477279368159 | 6.21669076584989e-14 | 0.409031156878587 |
| DLPFC | ADediting_900499 | chr2_75704851_- | 0.112063465115244 | 0.0904286828095434 | 0.204089548342341 | -0.0723280522119601 | 1.43062189672201e-09 | 0.335095440889141 |
| DLPFC | ADediting_900502 | chr2_75704854_- | 0.0505432277236822 | 0.111160371950726 | 0.360590880661171 | -0.0521005275038436 | 2.1661481275924e-12 | 0.384975402523202 |
| DLPFC | ADediting_900503 | chr2_75704855_- | 0.255422771618708 | 0.0647867993084055 | 0.145145680197479 | -0.082938439503132 | 1.81091289651652e-10 | 0.351935064841024 |
| DLPFC | ADediting_900504 | chr2_75704858_- | 0.332629249833656 | 0.0552069807780626 | 0.15954012820284 | -0.0800857949933614 | 4.25740121873809e-08 | 0.30501766929421 |
| CER | ADediting_900508 | chr2_75704880_- | 8.63830227206272e-05 | 0.314989668707407 | 0.00598531107247495 | 0.223445519426357 | 0.897661507198455 | -0.0105897461520963 |
| DLPFC | ADediting_900509 | chr2_75704888_- | 0.346451786242288 | 0.053651479277105 | 0.0950758001930446 | -0.0949740113753917 | 2.50893277371334e-08 | 0.309929939689708 |
| CER | ADediting_900509 | chr2_75704888_- | 7.44596675576519e-05 | 0.31769746093025 | 0.000723248282789694 | 0.273045669843327 | 0.600504586937286 | 0.043098550398821 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 2.04750673094674e-24 | 0.535620331685664 | 7.65103932043524e-20 | 0.48671737314149 | 2.75300395937433e-26 | 0.553553111463334 |
| AC | 9.51406977553654e-47 | 0.751778492197342 | 1.37978494694081e-34 | 0.674884332492979 | 1.12535592826731e-26 | 0.608125331366406 |
| PCC | 2.65898123155087e-25 | 0.660423440419328 | 1.27313603189816e-25 | 0.663707386959601 | 8.99872850748167e-09 | 0.400997323662802 |
| CER | 1.46352730356708e-08 | 0.442231860806843 | 3.40780370182784e-06 | 0.368854232085039 | 0.440841478211399 | 0.0634003779457011 |
| TCX | 2.43955251748199e-09 | 0.462982573212965 | 0.0462222884001299 | 0.163030213032828 | 1.21241264846749e-09 | 0.470719141605214 |
| FP | 2.17538221847247e-23 | 0.657298399030565 | 6.77984025194528e-31 | 0.72991650856851 | 0.0182083195104917 | 0.176839656602161 |
| IFG | 0.000363918355749205 | 0.656609828887165 | 0.00200071049711721 | 0.587834157595388 | 0.0430181402407149 | 0.407797446027458 |
| PG | 9.47137901581356e-46 | 0.816416353688121 | 1.85245924649643e-31 | 0.723708619801169 | 0.888258506051623 | 0.0103722032479616 |
| STG | 1.75040147238484e-14 | 0.716795092177187 | 2.65628316184961e-12 | 0.671762801499717 | 0.216226555477283 | 0.136338603772573 |
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Relation with AD stages for GCFC2 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 0.000238072717868789 | 0.346610056520345 |
| TCX | 0.000922067610071705 | 0.317221994012455 |
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RelatedDrugs for GCFC2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for GCFC2 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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