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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for SON |
 Gene summary |
| Gene information | Gene symbol | SON | Gene ID | 6651 |
| Gene name | SON DNA and RNA binding protein | |
| Synonyms | BASS1|C21orf50|DBP-5|NREBP|SON3|TOKIMS | |
| Cytomap | 21q22.11 | |
| Type of gene | protein-coding | |
| Description | protein SONBax antagonist selected in Saccharomyces 1NRE-binding proteinSON DNA binding proteinnegative regulatory element-binding protein | |
| Modification date | 20200313 | |
| UniProtAcc | P18583, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| SON | GO:0006397 | mRNA processing | 21504830 |
| SON | GO:0043066 | negative regulation of apoptotic process | 10509013 |
| SON | GO:0048024 | regulation of mRNA splicing, via spliceosome | 21504830 |
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RNA A-to-I events for SON |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_957027(33546666, +), ADediting_957028(33546722, +), ADediting_957029(33547068, +), ADediting_957030(33547074, +), ADediting_957031(33547075, +), ADediting_957032(33547101, +), ADediting_957033(33547104, +), ADediting_957034(33547162, +), ADediting_957035(33547165, +), ADediting_957036(33547243, +), ADediting_957037(33547244, +), ADediting_957038(33547256, +), ADediting_957039(33547930, +), ADediting_957040(33550495, +), ADediting_957041(33550950, +), ADediting_957042(33550969, +), ADediting_957043(33551013, +), ADediting_957044(33551799, +), ADediting_957045(33556593, +), ADediting_957046(33557386, +), ADediting_957047(33557387, +), ADediting_957048(33557388, +), ADediting_1641784(33546594, +), ADediting_1641785(33546603, +), ADediting_1641786(33546610, +), ADediting_1641787(33546625, +), ADediting_1641788(33546660, +), ADediting_1641789(33546661, +), ADediting_1641790(33546670, +), ADediting_1641791(33546678, +), ADediting_1641792(33546706, +), |
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RNA editing positional annotations for SON using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| ADediting_957040 | chr21_33550495_+ | nonsynonymous SNV | ENST00000356577.9 | c.A1264G | p.T422A | 0.006 | 0.282 | -1.65 |
| ADediting_957040 | chr21_33550495_+ | nonsynonymous SNV | ENST00000455528.5 | c.A1264G | p.T422A | 0.006 | 0.282 | -1.65 |
| ADediting_957040 | chr21_33550495_+ | nonsynonymous SNV | ENST00000300278.8 | c.A1264G | p.T422A | 0.006 | 0.282 | -1.65 |
| ADediting_957040 | chr21_33550495_+ | nonsynonymous SNV | ENST00000381679.8 | c.A1264G | p.T422A | 0.006 | 0.282 | -1.65 |
| ADediting_957041 | chr21_33550950_+ | synonymous SNV | ENST00000356577.9 | c.A1719G | p.P573P | . | . | . |
| ADediting_957041 | chr21_33550950_+ | synonymous SNV | ENST00000455528.5 | c.A1719G | p.P573P | . | . | . |
| ADediting_957041 | chr21_33550950_+ | synonymous SNV | ENST00000300278.8 | c.A1719G | p.P573P | . | . | . |
| ADediting_957041 | chr21_33550950_+ | synonymous SNV | ENST00000381679.8 | c.A1719G | p.P573P | . | . | . |
| ADediting_957042 | chr21_33550969_+ | nonsynonymous SNV | ENST00000356577.9 | c.A1738G | p.R580G | 0.155 | 0.008 | -1.89 |
| ADediting_957042 | chr21_33550969_+ | nonsynonymous SNV | ENST00000455528.5 | c.A1738G | p.R580G | 0.155 | 0.008 | -1.89 |
| ADediting_957042 | chr21_33550969_+ | nonsynonymous SNV | ENST00000300278.8 | c.A1738G | p.R580G | 0.155 | 0.008 | -1.89 |
| ADediting_957042 | chr21_33550969_+ | nonsynonymous SNV | ENST00000381679.8 | c.A1738G | p.R580G | 0.155 | 0.008 | -1.89 |
| ADediting_957043 | chr21_33551013_+ | synonymous SNV | ENST00000356577.9 | c.A1782G | p.L594L | . | . | . |
| ADediting_957043 | chr21_33551013_+ | synonymous SNV | ENST00000455528.5 | c.A1782G | p.L594L | . | . | . |
| ADediting_957043 | chr21_33551013_+ | synonymous SNV | ENST00000300278.8 | c.A1782G | p.L594L | . | . | . |
| ADediting_957043 | chr21_33551013_+ | synonymous SNV | ENST00000381679.8 | c.A1782G | p.L594L | . | . | . |
| ADediting_957044 | chr21_33551799_+ | synonymous SNV | ENST00000356577.9 | c.A2568G | p.L856L | . | . | . |
| ADediting_957044 | chr21_33551799_+ | synonymous SNV | ENST00000455528.5 | c.A2568G | p.L856L | . | . | . |
| ADediting_957044 | chr21_33551799_+ | synonymous SNV | ENST00000300278.8 | c.A2568G | p.L856L | . | . | . |
| ADediting_957044 | chr21_33551799_+ | synonymous SNV | ENST00000381679.8 | c.A2568G | p.L856L | . | . | . |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_957027 | chr21_33546666_+ | intronic |
| ADediting_957028 | chr21_33546722_+ | intronic |
| ADediting_957029 | chr21_33547068_+ | intronic |
| ADediting_957030 | chr21_33547074_+ | intronic |
| ADediting_957031 | chr21_33547075_+ | intronic |
| ADediting_957032 | chr21_33547101_+ | intronic |
| ADediting_957033 | chr21_33547104_+ | intronic |
| ADediting_957034 | chr21_33547162_+ | intronic |
| ADediting_957035 | chr21_33547165_+ | intronic |
| ADediting_957036 | chr21_33547243_+ | intronic |
| ADediting_957037 | chr21_33547244_+ | intronic |
| ADediting_957038 | chr21_33547256_+ | intronic |
| ADediting_957039 | chr21_33547930_+ | intronic |
| ADediting_957040 | chr21_33550495_+ | exonic |
| ADediting_957041 | chr21_33550950_+ | exonic |
| ADediting_957042 | chr21_33550969_+ | exonic |
| ADediting_957043 | chr21_33551013_+ | exonic |
| ADediting_957044 | chr21_33551799_+ | exonic |
| ADediting_957045 | chr21_33556593_+ | intronic |
| ADediting_957046 | chr21_33557386_+ | intronic |
| ADediting_957047 | chr21_33557387_+ | intronic |
| ADediting_957048 | chr21_33557388_+ | intronic |
| ADediting_1641784 | chr21_33546594_+ | intronic |
| ADediting_1641785 | chr21_33546603_+ | intronic |
| ADediting_1641786 | chr21_33546610_+ | intronic |
| ADediting_1641787 | chr21_33546625_+ | intronic |
| ADediting_1641788 | chr21_33546660_+ | intronic |
| ADediting_1641789 | chr21_33546661_+ | intronic |
| ADediting_1641790 | chr21_33546670_+ | intronic |
| ADediting_1641791 | chr21_33546678_+ | intronic |
| ADediting_1641792 | chr21_33546706_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_957027 | chr21_33546666_+ | SINE | Alu | Name=AluSq2 |
| ADediting_957028 | chr21_33546722_+ | SINE | Alu | Name=AluSq2 |
| ADediting_957029 | chr21_33547068_+ | SINE | Alu | Name=AluSq2 |
| ADediting_957030 | chr21_33547074_+ | SINE | Alu | Name=AluSq2 |
| ADediting_957031 | chr21_33547075_+ | SINE | Alu | Name=AluSq2 |
| ADediting_957032 | chr21_33547101_+ | SINE | Alu | Name=AluSq2 |
| ADediting_957033 | chr21_33547104_+ | SINE | Alu | Name=AluSq2 |
| ADediting_957034 | chr21_33547162_+ | SINE | Alu | Name=AluSq2 |
| ADediting_957035 | chr21_33547165_+ | SINE | Alu | Name=AluSq2 |
| ADediting_957036 | chr21_33547243_+ | SINE | Alu | Name=AluSq2 |
| ADediting_957037 | chr21_33547244_+ | SINE | Alu | Name=AluSq2 |
| ADediting_957038 | chr21_33547256_+ | SINE | Alu | Name=AluSq2 |
| ADediting_957039 | chr21_33547930_+ | SINE | Alu | Name=AluY |
| ADediting_957045 | chr21_33556593_+ | SINE | Alu | Name=AluSx3 |
| ADediting_1641784 | chr21_33546594_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1641785 | chr21_33546603_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1641786 | chr21_33546610_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1641787 | chr21_33546625_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1641788 | chr21_33546660_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1641789 | chr21_33546661_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1641790 | chr21_33546670_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1641791 | chr21_33546678_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1641792 | chr21_33546706_+ | SINE | Alu | Name=AluSq2 |
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RNA A-to-I editing events in the alternative splicing sites for SON |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| ES | ADediting_957029 | chr21_33547068_+ | 33547067:33547075 | 5ss | 2e | CAGGTTCAA | 1.19 | CGGGTTCAA | -6.26 |
| ES | ADediting_957030 | chr21_33547074_+ | 33547067:33547075 | 5ss | 5i | CAGGTTCAA | 1.19 | CAGGTTCGA | 5.36 |
| ES | ADediting_957031 | chr21_33547075_+ | 33547067:33547075 | 5ss | 6i | CAGGTTCAA | 1.19 | CAGGTTCAG | 2.78 |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SON |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for SON |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for SON |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337757 | chr7_5495852_- | ENSG00000159140.20 | ENST00000381679.8 | SON-203 | hsa-miR-589-3p | chr21 | 33558865 | 33558871 | 7mer-m8 | 33558849 | 33558872 | 145 | -17.06 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000159140.20 | ENST00000381679.8 | SON-203 | hsa-miR-5585-3p | chr21 | 33557641 | 33557647 | 7mer-m8 | 33557625 | 33557648 | 151 | -21.24 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000159140.20 | ENST00000381679.8 | SON-203 | hsa-miR-4477b | chr21 | 33558361 | 33558368 | 8mer-1a | 33558346 | 33558368 | 152 | -9.23 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000159140.20 | ENST00000381679.8 | SON-203 | hsa-miR-4477b | chr21 | 33558361 | 33558368 | 8mer-1a | 33558346 | 33558368 | 152 | -9.23 |
| ADediting_1535953 | chr14_101045971_+ | ENSG00000159140.20 | ENST00000381679.8 | SON-203 | hsa-miR-381-3p | chr21 | 33558202 | 33558209 | 8mer-1a | 33558188 | 33558209 | 146 | -9.84 |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000159140.20 | ENST00000381679.8 | SON-203 | hsa-miR-381-3p | chr21 | 33558202 | 33558209 | 8mer-1a | 33558188 | 33558209 | 146 | -9.84 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000159140.20 | ENST00000381679.8 | SON-203 | hsa-miR-641 | chr21 | 33558948 | 33558954 | 7mer-m8 | 33558932 | 33558955 | 142 | -14.91 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000159140.20 | ENST00000381679.8 | SON-203 | hsa-miR-641 | chr21 | 33558948 | 33558954 | 7mer-m8 | 33558932 | 33558955 | 142 | -14.91 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000159140.20 | ENST00000381679.8 | SON-203 | hsa-miR-4775 | chr21 | 33557737 | 33557743 | 7mer-1a | 33557721 | 33557743 | 145 | -17.11 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000159140.20 | ENST00000381679.8 | SON-203 | hsa-miR-4775 | chr21 | 33558531 | 33558538 | 8mer-1a | 33558517 | 33558538 | 151 | -7.56 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for SON |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000356577.9 | protein_coding |  |  |
| ENST00000300278.8 | protein_coding |  |  |
| ENST00000381679.8 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_957040 | ENST00000356577.9 | chr21_33550495_+ | 1319 | -2741.90 | -2737.70 | -2752.60 |
| ADediting_957041 | ENST00000356577.9 | chr21_33550950_+ | 1774 | -2738.90 | -2737.70 | -2752.60 |
| ADediting_957042 | ENST00000356577.9 | chr21_33550969_+ | 1793 | -2740.30 | -2737.70 | -2752.60 |
| ADediting_957043 | ENST00000356577.9 | chr21_33551013_+ | 1837 | -2742.80 | -2737.70 | -2752.60 |
| ADediting_957044 | ENST00000356577.9 | chr21_33551799_+ | 2623 | -2739.50 | -2737.70 | -2752.60 |
| ADediting_957040 | ENST00000300278.8 | chr21_33550495_+ | 1293 | -2493.90 | -2489.70 | -2504.60 |
| ADediting_957041 | ENST00000300278.8 | chr21_33550950_+ | 1748 | -2490.90 | -2489.70 | -2504.60 |
| ADediting_957042 | ENST00000300278.8 | chr21_33550969_+ | 1767 | -2492.30 | -2489.70 | -2504.60 |
| ADediting_957043 | ENST00000300278.8 | chr21_33551013_+ | 1811 | -2494.80 | -2489.70 | -2504.60 |
| ADediting_957044 | ENST00000300278.8 | chr21_33551799_+ | 2597 | -2491.50 | -2489.70 | -2504.60 |
| ADediting_957040 | ENST00000381679.8 | chr21_33550495_+ | 1292 | -2584.60 | -2580.40 | -2595.30 |
| ADediting_957041 | ENST00000381679.8 | chr21_33550950_+ | 1747 | -2581.60 | -2580.40 | -2595.30 |
| ADediting_957042 | ENST00000381679.8 | chr21_33550969_+ | 1766 | -2583.00 | -2580.40 | -2595.30 |
| ADediting_957043 | ENST00000381679.8 | chr21_33551013_+ | 1810 | -2585.50 | -2580.40 | -2595.30 |
| ADediting_957044 | ENST00000381679.8 | chr21_33551799_+ | 2596 | -2582.20 | -2580.40 | -2595.30 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for SON |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_957040 | chr21_33550495_+ | 2.99366957095091e-06 | 0.261727664397428 | 1.65217450813129e-08 | 0.313748176047487 | 0.317138596793604 | -0.057000424841945 |
| CER | ADediting_957040 | chr21_33550495_+ | 3.78140625620148e-11 | 0.506472739942038 | 1.44565411520741e-12 | 0.536716167209527 | 0.0337136201796219 | 0.173515570603164 |
| DLPFC | ADediting_957042 | chr21_33550969_+ | 3.71694326835735e-06 | 0.259312954333071 | 2.47239387552213e-08 | 0.31006494578339 | 0.170268694346063 | -0.078083407267865 |
| CER | ADediting_957042 | chr21_33550969_+ | 2.8805330094077e-10 | 0.486041156298169 | 8.94128629435396e-13 | 0.540925354146511 | 0.946433537877519 | 0.00553195901617054 |
| TCX | ADediting_957042 | chr21_33550969_+ | 0.230702892147837 | 0.0984468506680082 | 4.35756943973561e-07 | 0.398648565837778 | 0.00177066615374376 | -0.253200544060075 |
| FP | ADediting_957042 | chr21_33550969_+ | 0.00710094414042508 | 0.201130152964554 | 2.22480964481359e-05 | 0.312101723021007 | 0.00529362748368189 | -0.208186048760734 |
| STG | ADediting_957042 | chr21_33550969_+ | 0.000208041899033293 | 0.394087974032694 | 1.9411131166308e-05 | 0.447844902531528 | 0.0762052663746795 | -0.194527672412881 |
| CER | ADediting_957043 | chr21_33551013_+ | 9.76044043969585e-09 | 0.447046534255282 | 2.64883273162989e-12 | 0.531326709826227 | 0.0124482943238194 | 0.203617695058008 |
| TCX | ADediting_957043 | chr21_33551013_+ | 8.54991083946114e-06 | 0.354508412473473 | 2.84959661171647e-07 | 0.404453513867978 | 0.0450649765252944 | -0.163892667437494 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 0.000672193978498492 | 0.192119242857459 | 7.12623160252476e-11 | 0.35921822406452 | 0.00132349297508063 | 0.181578492263994 |
| AC | 5.20790952761511e-70 | 0.847008289819292 | 3.16013296153743e-46 | 0.748968630978435 | 2.68274763178603e-21 | 0.551523535681374 |
| PCC | 1.29337895681591e-24 | 0.65322742466188 | 1.13826725414081e-23 | 0.643004490352773 | 0.000774639505186685 | 0.241225459000546 |
| CER | 2.09979408877095e-57 | 0.906846029405872 | 3.81630405458505e-35 | 0.803426796512074 | 0.000438201625580305 | 0.2835327961893 |
| TCX | 4.82548713666475e-28 | 0.747160592740131 | 0.000709550626018962 | 0.273453509344206 | 2.56470101611593e-15 | 0.587960224471203 |
| FP | 5.28809772097241e-34 | 0.754394432595795 | 1.24434050081171e-25 | 0.681319595638645 | 2.79159520539887e-05 | 0.308519547749415 |
| IFG | 6.14448486609407e-07 | 0.81732460325686 | 0.0017448147132803 | 0.593976891515204 | 0.00220748352781181 | 0.58334385920557 |
| PG | 6.3741350120505e-45 | 0.812140470238453 | 3.30812570918382e-28 | 0.695407914284856 | 0.235408087734661 | 0.0874241936590068 |
| STG | 1.58576007680701e-20 | 0.807926109710989 | 8.9040805699845e-15 | 0.722260522160539 | 0.0258930065326252 | 0.243058628105823 |
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Relation with AD stages for SON |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_957040 | chr21_33550495_+ | 8.93690409515281e-05 | 0.367955277077954 |
| CER | ADediting_957043 | chr21_33551013_+ | 1.22370321696711e-05 | 0.407176684526004 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 1.27773994954881e-06 | 0.446470661497967 |
| TCX | 9.64977265611241e-13 | 0.623288111341868 |
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RelatedDrugs for SON |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for SON |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| SON | C4310696 | ZTTK SYNDROME | 4 | CTD_human;ORPHANET;UNIPROT |
| SON | C0010606 | Adenoid Cystic Carcinoma | 1 | CTD_human |
| SON | C0036095 | Salivary Gland Neoplasms | 1 | CTD_human |
| SON | C0220636 | Malignant neoplasm of salivary gland | 1 | CTD_human |
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