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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for SLIT1

check button Gene summary
Gene informationGene symbol

SLIT1

Gene ID

6585

Gene nameslit guidance ligand 1
SynonymsMEGF4|SLIL1|SLIT-1|SLIT3
Cytomap

10q24.1

Type of geneprotein-coding
Descriptionslit homolog 1 proteinmultiple EGF-like domains protein 4multiple epidermal growth factor-like domains protein 4slit homolog 1
Modification date20200313
UniProtAcc

O75093,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
SLIT1

GO:0007411

axon guidance

11748139

SLIT1

GO:0021834

chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration

11748139

SLIT1

GO:0048846

axon extension involved in axon guidance

16840550

SLIT1

GO:0050919

negative chemotaxis

11748139


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RNA A-to-I events for SLIT1

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_227430(97008438, -), ADediting_227431(97008450, -), ADediting_227432(97008512, -), ADediting_227433(97009043, -), ADediting_227434(97009053, -), ADediting_227435(97009061, -), ADediting_227436(97009078, -), ADediting_227437(97009149, -), ADediting_227438(97014610, -), ADediting_227439(97014675, -), ADediting_227440(97014701, -), ADediting_227441(97014736, -), ADediting_227442(97014738, -), ADediting_227443(97014744, -), ADediting_227444(97014754, -), ADediting_227445(97014803, -), ADediting_227446(97014806, -), ADediting_227447(97014844, -), ADediting_227448(97016052, -), ADediting_227449(97016064, -), ADediting_227450(97016065, -), ADediting_227451(97016066, -), ADediting_227452(97016091, -), ADediting_227453(97016126, -), ADediting_227454(97016185, -), ADediting_227455(97016200, -), ADediting_227456(97016222, -), ADediting_227457(97016226, -), ADediting_227458(97016246, -), ADediting_227459(97016429, -), ADediting_227460(97016469, -), ADediting_227461(97016484, -), ADediting_227462(97016493, -), ADediting_227463(97016498, -), ADediting_227464(97016520, -), ADediting_227465(97016528, -), ADediting_227466(97016534, -), ADediting_227467(97016536, -), ADediting_227468(97016542, -), ADediting_227469(97016549, -), ADediting_227470(97016550, -), ADediting_227471(97016556, -), ADediting_227472(97016559, -), ADediting_227473(97016560, -), ADediting_227474(97016626, -), ADediting_227475(97016635, -), ADediting_227476(97016641, -), ADediting_227477(97017914, -), ADediting_227478(97017916, -), ADediting_227479(97017938, -), ADediting_227480(97018013, -), ADediting_227481(97018031, -), ADediting_227482(97018048, -), ADediting_227483(97018076, -), ADediting_227484(97018119, -), ADediting_227485(97018120, -), ADediting_227486(97023345, -), ADediting_227487(97023901, -), ADediting_227488(97033146, -), ADediting_227489(97034140, -), ADediting_227490(97051729, -), ADediting_227491(97052299, -), ADediting_227492(97052379, -), ADediting_227493(97054324, -), ADediting_227494(97054416, -), ADediting_227495(97054418, -), ADediting_227496(97054434, -), ADediting_227497(97054457, -), ADediting_227498(97055024, -), ADediting_227499(97055154, -), ADediting_227500(97072297, -), ADediting_227501(97078055, -), ADediting_227502(97082573, -), ADediting_227503(97083722, -), ADediting_227504(97084806, -), ADediting_227505(97085659, -), ADediting_227506(97086344, -), ADediting_227507(97112550, -), ADediting_227508(97112609, -), ADediting_227509(97112737, -), ADediting_227510(97112786, -), ADediting_227511(97114436, -), ADediting_227512(97114458, -), ADediting_227513(97114526, -), ADediting_227514(97114529, -), ADediting_227515(97114564, -), ADediting_227516(97114644, -), ADediting_227517(97141938, -), ADediting_227518(97141976, -), ADediting_227519(97144076, -), ADediting_227520(97145256, -), ADediting_227521(97145282, -), ADediting_227522(97145367, -), ADediting_227523(97145389, -), ADediting_227524(97148427, -), ADediting_227525(97160823, -), ADediting_227526(97160829, -), ADediting_227527(97160832, -), ADediting_227528(97160849, -), ADediting_227529(97162353, -), ADediting_227530(97162501, -), ADediting_227531(97163638, -), ADediting_227532(97171575, -), ADediting_227533(97173583, -), ADediting_1608038(97054417, -), ADediting_1608039(97054421, -), ADediting_1608040(97054422, -), ADediting_1608041(97118732, -),

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RNA editing positional annotations for SLIT1 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_227430chr10_97008438_-intronic
ADediting_227431chr10_97008450_-intronic
ADediting_227432chr10_97008512_-intronic
ADediting_227433chr10_97009043_-intronic
ADediting_227434chr10_97009053_-intronic
ADediting_227435chr10_97009061_-intronic
ADediting_227436chr10_97009078_-intronic
ADediting_227437chr10_97009149_-intronic
ADediting_227438chr10_97014610_-intronic
ADediting_227439chr10_97014675_-intronic
ADediting_227440chr10_97014701_-intronic
ADediting_227441chr10_97014736_-intronic
ADediting_227442chr10_97014738_-intronic
ADediting_227443chr10_97014744_-intronic
ADediting_227444chr10_97014754_-intronic
ADediting_227445chr10_97014803_-intronic
ADediting_227446chr10_97014806_-intronic
ADediting_227447chr10_97014844_-intronic
ADediting_227448chr10_97016052_-intronic
ADediting_227449chr10_97016064_-intronic
ADediting_227450chr10_97016065_-intronic
ADediting_227451chr10_97016066_-intronic
ADediting_227452chr10_97016091_-intronic
ADediting_227453chr10_97016126_-intronic
ADediting_227454chr10_97016185_-intronic
ADediting_227455chr10_97016200_-intronic
ADediting_227456chr10_97016222_-intronic
ADediting_227457chr10_97016226_-intronic
ADediting_227458chr10_97016246_-intronic
ADediting_227459chr10_97016429_-intronic
ADediting_227460chr10_97016469_-intronic
ADediting_227461chr10_97016484_-intronic
ADediting_227462chr10_97016493_-intronic
ADediting_227463chr10_97016498_-intronic
ADediting_227464chr10_97016520_-intronic
ADediting_227465chr10_97016528_-intronic
ADediting_227466chr10_97016534_-intronic
ADediting_227467chr10_97016536_-intronic
ADediting_227468chr10_97016542_-intronic
ADediting_227469chr10_97016549_-intronic
ADediting_227470chr10_97016550_-intronic
ADediting_227471chr10_97016556_-intronic
ADediting_227472chr10_97016559_-intronic
ADediting_227473chr10_97016560_-intronic
ADediting_227474chr10_97016626_-intronic
ADediting_227475chr10_97016635_-intronic
ADediting_227476chr10_97016641_-intronic
ADediting_227477chr10_97017914_-intronic
ADediting_227478chr10_97017916_-intronic
ADediting_227479chr10_97017938_-intronic
ADediting_227480chr10_97018013_-intronic
ADediting_227481chr10_97018031_-intronic
ADediting_227482chr10_97018048_-intronic
ADediting_227483chr10_97018076_-intronic
ADediting_227484chr10_97018119_-intronic
ADediting_227485chr10_97018120_-intronic
ADediting_227486chr10_97023345_-intronic
ADediting_227487chr10_97023901_-intronic
ADediting_227488chr10_97033146_-intronic
ADediting_227489chr10_97034140_-intronic
ADediting_227490chr10_97051729_-intronic
ADediting_227491chr10_97052299_-intronic
ADediting_227492chr10_97052379_-intronic
ADediting_227493chr10_97054324_-intronic
ADediting_227494chr10_97054416_-intronic
ADediting_227495chr10_97054418_-intronic
ADediting_227496chr10_97054434_-intronic
ADediting_227497chr10_97054457_-intronic
ADediting_227498chr10_97055024_-intronic
ADediting_227499chr10_97055154_-intronic
ADediting_227500chr10_97072297_-intronic
ADediting_227501chr10_97078055_-intronic
ADediting_227502chr10_97082573_-intronic
ADediting_227503chr10_97083722_-intronic
ADediting_227504chr10_97084806_-intronic
ADediting_227505chr10_97085659_-intronic
ADediting_227506chr10_97086344_-intronic
ADediting_227507chr10_97112550_-intronic
ADediting_227508chr10_97112609_-intronic
ADediting_227509chr10_97112737_-intronic
ADediting_227510chr10_97112786_-intronic
ADediting_227511chr10_97114436_-intronic
ADediting_227512chr10_97114458_-intronic
ADediting_227513chr10_97114526_-intronic
ADediting_227514chr10_97114529_-intronic
ADediting_227515chr10_97114564_-intronic
ADediting_227516chr10_97114644_-intronic
ADediting_227517chr10_97141938_-intronic
ADediting_227518chr10_97141976_-intronic
ADediting_227519chr10_97144076_-intronic
ADediting_227520chr10_97145256_-intronic
ADediting_227521chr10_97145282_-intronic
ADediting_227522chr10_97145367_-intronic
ADediting_227523chr10_97145389_-intronic
ADediting_227524chr10_97148427_-intronic
ADediting_227525chr10_97160823_-intronic
ADediting_227526chr10_97160829_-intronic
ADediting_227527chr10_97160832_-intronic
ADediting_227528chr10_97160849_-intronic
ADediting_227529chr10_97162353_-intronic
ADediting_227530chr10_97162501_-intronic
ADediting_227531chr10_97163638_-intronic
ADediting_227532chr10_97171575_-intronic
ADediting_227533chr10_97173583_-intronic
ADediting_1608038chr10_97054417_-intronic
ADediting_1608039chr10_97054421_-intronic
ADediting_1608040chr10_97054422_-intronic
ADediting_1608041chr10_97118732_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_227430chr10_97008438_-SINEAluName=AluSq2
ADediting_227431chr10_97008450_-SINEAluName=AluSq2
ADediting_227432chr10_97008512_-SINEAluName=AluSq2
ADediting_227433chr10_97009043_-SINEAluName=AluYj4
ADediting_227434chr10_97009053_-SINEAluName=AluYj4
ADediting_227435chr10_97009061_-SINEAluName=AluYj4
ADediting_227436chr10_97009078_-SINEAluName=AluYj4
ADediting_227437chr10_97009149_-SINEAluName=AluYj4
ADediting_227438chr10_97014610_-SINEAluName=AluSx
ADediting_227439chr10_97014675_-SINEAluName=AluSx
ADediting_227440chr10_97014701_-SINEAluName=AluSx
ADediting_227441chr10_97014736_-SINEAluName=AluSx
ADediting_227442chr10_97014738_-SINEAluName=AluSx
ADediting_227443chr10_97014744_-SINEAluName=AluSx
ADediting_227444chr10_97014754_-SINEAluName=AluSx
ADediting_227445chr10_97014803_-SINEAluName=AluSx
ADediting_227446chr10_97014806_-SINEAluName=AluSx
ADediting_227447chr10_97014844_-SINEAluName=AluSx
ADediting_227448chr10_97016052_-SINEAluName=AluSz
ADediting_227449chr10_97016064_-SINEAluName=AluSz
ADediting_227450chr10_97016065_-SINEAluName=AluSz
ADediting_227451chr10_97016066_-SINEAluName=AluSz
ADediting_227452chr10_97016091_-SINEAluName=AluSz
ADediting_227453chr10_97016126_-SINEAluName=AluSz
ADediting_227454chr10_97016185_-SINEAluName=AluSz
ADediting_227455chr10_97016200_-SINEAluName=AluSz
ADediting_227456chr10_97016222_-SINEAluName=AluSz
ADediting_227457chr10_97016226_-SINEAluName=AluSz
ADediting_227458chr10_97016246_-SINEAluName=AluSz
ADediting_227459chr10_97016429_-SINEAluName=AluJr
ADediting_227460chr10_97016469_-SINEAluName=AluJr
ADediting_227461chr10_97016484_-SINEAluName=AluJr
ADediting_227462chr10_97016493_-SINEAluName=AluJr
ADediting_227463chr10_97016498_-SINEAluName=AluJr
ADediting_227464chr10_97016520_-SINEAluName=AluJr
ADediting_227465chr10_97016528_-SINEAluName=AluJr
ADediting_227466chr10_97016534_-SINEAluName=AluJr
ADediting_227467chr10_97016536_-SINEAluName=AluJr
ADediting_227468chr10_97016542_-SINEAluName=AluJr
ADediting_227469chr10_97016549_-SINEAluName=AluJr
ADediting_227470chr10_97016550_-SINEAluName=AluJr
ADediting_227471chr10_97016556_-SINEAluName=AluJr
ADediting_227472chr10_97016559_-SINEAluName=AluJr
ADediting_227473chr10_97016560_-SINEAluName=AluJr
ADediting_227474chr10_97016626_-SINEAluName=AluJr
ADediting_227475chr10_97016635_-SINEAluName=AluJr
ADediting_227476chr10_97016641_-SINEAluName=AluJr
ADediting_227477chr10_97017914_-SINEAluName=AluSq4
ADediting_227478chr10_97017916_-SINEAluName=AluSq4
ADediting_227479chr10_97017938_-SINEAluName=AluSq4
ADediting_227480chr10_97018013_-SINEAluName=AluSq4
ADediting_227481chr10_97018031_-SINEAluName=AluSq4
ADediting_227482chr10_97018048_-SINEAluName=AluSq4
ADediting_227483chr10_97018076_-SINEAluName=AluSq4
ADediting_227484chr10_97018119_-SINEAluName=AluSq4
ADediting_227485chr10_97018120_-SINEAluName=AluSq4
ADediting_227486chr10_97023345_-SINEAluName=AluSz6
ADediting_227487chr10_97023901_-SINEAluName=AluSq2
ADediting_227488chr10_97033146_-SINEAluName=AluJb
ADediting_227489chr10_97034140_-SINEAluName=AluSx1
ADediting_227490chr10_97051729_-SINEAluName=AluSg7
ADediting_227491chr10_97052299_-SINEAluName=AluJr
ADediting_227492chr10_97052379_-SINEAluName=AluJr
ADediting_227493chr10_97054324_-LTRERVL-MaLRName=MSTB
ADediting_227494chr10_97054416_-LTRERVL-MaLRName=MSTB
ADediting_227495chr10_97054418_-LTRERVL-MaLRName=MSTB
ADediting_227496chr10_97054434_-LTRERVL-MaLRName=MSTB
ADediting_227497chr10_97054457_-LTRERVL-MaLRName=MSTB
ADediting_227498chr10_97055024_-SINEAluName=AluSx3
ADediting_227499chr10_97055154_-SINEAluName=AluSx3
ADediting_227500chr10_97072297_-SINEAluName=AluJo
ADediting_227501chr10_97078055_-SINEAluName=AluJr
ADediting_227502chr10_97082573_-SINEAluName=AluY
ADediting_227504chr10_97084806_-SINEAluName=AluSz6
ADediting_227505chr10_97085659_-SINEAluName=AluSg
ADediting_227506chr10_97086344_-SINEAluName=AluSx
ADediting_227507chr10_97112550_-SINEMIRName=MIRb
ADediting_227508chr10_97112609_-SINEMIRName=MIRb
ADediting_227509chr10_97112737_-SINEAluName=AluJb
ADediting_227510chr10_97112786_-SINEAluName=AluJb
ADediting_227511chr10_97114436_-SINEAluName=AluJr
ADediting_227512chr10_97114458_-SINEAluName=AluJr
ADediting_227513chr10_97114526_-SINEAluName=AluJr
ADediting_227514chr10_97114529_-SINEAluName=AluJr
ADediting_227515chr10_97114564_-SINEAluName=AluJr
ADediting_227516chr10_97114644_-SINEAluName=AluJr
ADediting_227517chr10_97141938_-SINEAluName=AluJo
ADediting_227518chr10_97141976_-SINEAluName=AluJo
ADediting_227519chr10_97144076_-SINEAluName=AluSx1
ADediting_227520chr10_97145256_-SINEAluName=AluSg
ADediting_227521chr10_97145282_-SINEAluName=AluSg
ADediting_227522chr10_97145367_-SINEAluName=AluSg
ADediting_227523chr10_97145389_-SINEAluName=AluSg
ADediting_227524chr10_97148427_-SINEAluName=AluJr
ADediting_227525chr10_97160823_-SINEAluName=AluSz
ADediting_227526chr10_97160829_-SINEAluName=AluSz
ADediting_227527chr10_97160832_-SINEAluName=AluSz
ADediting_227528chr10_97160849_-SINEAluName=AluSz
ADediting_227529chr10_97162353_-SINEAluName=AluSx
ADediting_227530chr10_97162501_-SINEAluName=AluSx
ADediting_227532chr10_97171575_-SINEAluName=AluSx1
ADediting_227533chr10_97173583_-SINEAluName=AluJb
ADediting_1608038chr10_97054417_-LTRERVL-MaLRName=MSTB
ADediting_1608039chr10_97054421_-LTRERVL-MaLRName=MSTB
ADediting_1608040chr10_97054422_-LTRERVL-MaLRName=MSTB
ADediting_1608041chr10_97118732_-SINEMIRName=MIRb

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RNA A-to-I editing events in the alternative splicing sites for SLIT1

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SLIT1

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
boxplot
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
Soverview

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for SLIT1

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for SLIT1


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337757chr7_5495852_-ENSG00000187122.17ENST00000266058.9SLIT1-201hsa-miR-589-3pchr1096999017969990237mer-m89699901696999037145-21.09
ADediting_1556067chr19_40282625_-ENSG00000187122.17ENST00000266058.9SLIT1-201hsa-miR-641chr1096999360969993678mer-1a9699936096999379147-21.76
ADediting_291761chr11_93733708_-ENSG00000187122.17ENST00000266058.9SLIT1-201hsa-miR-1304-3pchr1096998632969986387mer-m89699863196998652140-15.76
ADediting_496066chr15_66496985_-ENSG00000187122.17ENST00000266058.9SLIT1-201hsa-miR-4512chr1097001069970010757mer-1a9700106997001088140-31.33
ADediting_843620chr2_207754818_+ENSG00000187122.17ENST00000266058.9SLIT1-201hsa-miR-4775chr1096998552969985587mer-m89699855196998570145-11.38

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1097295chr3_85385762_+ENSG00000187122.17ENST00000266058.9SLIT1-201hsa-miR-5688chr1096998811969988177mer-m89699881096998831145-11.88
ADediting_291761chr11_93733708_-ENSG00000187122.17ENST00000266058.9SLIT1-201hsa-miR-1304-3pchr1096999420969994267mer-m89699941996999438145-17.37
ADediting_496066chr15_66496985_-ENSG00000187122.17ENST00000266058.9SLIT1-201hsa-miR-4512chr1096999709969997157mer-m89699970896999731150-28.09
ADediting_98288chr1_32086990_+ENSG00000187122.17ENST00000266058.9SLIT1-201hsa-miR-5585-3pchr1096998593969985997mer-m89699859296998616142-10.07
ADediting_98289chr1_32086992_+ENSG00000187122.17ENST00000266058.9SLIT1-201hsa-miR-5585-3pchr1096998593969985997mer-m89699859296998616142-10.07

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for SLIT1

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for SLIT1

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_227432chr10_97008512_-0.155621515984840.08084240932680720.914453645498391-0.00612588934097873.03037497897613e-150.428076903589713
DLPFCADediting_227509chr10_97112737_-0.3799040346378130.05004210734846420.574738286297066-0.03198866510328339.47614906431068e-130.390753103042026
DLPFCADediting_227511chr10_97114436_-0.7386672207612910.01902341036154190.780529595205957-0.0158882465000142.62290695031558e-090.329958504405589

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC3.54795425694015e-710.8029108210664316.61472805580352e-930.8620424197381770.01378377380049590.139757879811486
AC4.69158471591426e-340.6708902770509019.72373093127956e-200.5328513244074871.57108101649992e-220.565497106292889
PCC6.46708794752611e-370.757972235869574.58323978340478e-260.6681954453085820.5839525741496860.0398703821173356
TCX6.66517088688433e-180.6290758620619323.58346418962597e-230.697441135677470.000375639402307355-0.286676414385739
FP1.24732619934168e-390.7924029951504892.28890222856332e-210.6335811665645891.26318996008924e-050.320840660057958
IFG2.31766516099633e-070.8333934858601761.18029658867531e-060.8056184244521820.8474393860422560.0405369267126186
PG3.10240747425188e-050.3003929250902921.00781251797966e-080.4047154930736820.60315185930077-0.0383635457181745
STG3.4286910768156e-160.7468881152734953.89600899045907e-090.5886131781773770.8021885288205590.0277439603145225

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Relation with AD stages for SLIT1

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
PG7.86941579820166e-07-0.352781652911881

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RelatedDrugs for SLIT1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for SLIT1

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource