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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for SLC6A11 |
 Gene summary |
| Gene information | Gene symbol | SLC6A11 | Gene ID | 6538 |
| Gene name | solute carrier family 6 member 11 | |
| Synonyms | GAT-3|GAT3|GAT4 | |
| Cytomap | 3p25.3 | |
| Type of gene | protein-coding | |
| Description | sodium- and chloride-dependent GABA transporter 3GABA transporter 3solute carrier family 6 (neurotransmitter transporter), member 11solute carrier family 6 (neurotransmitter transporter, GABA), member 11 | |
| Modification date | 20200313 | |
| UniProtAcc | P48066, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for SLC6A11 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_1010041(10824946, +), ADediting_1010042(10824964, +), ADediting_1010043(10824983, +), ADediting_1010044(10825025, +), ADediting_1010045(10825061, +), ADediting_1010046(10825062, +), ADediting_1010047(10825075, +), ADediting_1010048(10825085, +), ADediting_1010049(10825102, +), ADediting_1010050(10825103, +), ADediting_1010051(10825117, +), ADediting_1010052(10833118, +), ADediting_1010053(10833126, +), ADediting_1010054(10833131, +), ADediting_1010055(10833174, +), ADediting_1010056(10833187, +), ADediting_1010057(10833201, +), ADediting_1010058(10833242, +), ADediting_1010059(10833245, +), ADediting_1010090(10886636, +), |
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RNA editing positional annotations for SLC6A11 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_1010041 | chr3_10824946_+ | UTR3 |
| ADediting_1010042 | chr3_10824964_+ | UTR3 |
| ADediting_1010043 | chr3_10824983_+ | UTR3 |
| ADediting_1010044 | chr3_10825025_+ | UTR3 |
| ADediting_1010045 | chr3_10825061_+ | UTR3 |
| ADediting_1010046 | chr3_10825062_+ | UTR3 |
| ADediting_1010047 | chr3_10825075_+ | UTR3 |
| ADediting_1010048 | chr3_10825085_+ | UTR3 |
| ADediting_1010049 | chr3_10825102_+ | UTR3 |
| ADediting_1010050 | chr3_10825103_+ | UTR3 |
| ADediting_1010051 | chr3_10825117_+ | UTR3 |
| ADediting_1010052 | chr3_10833118_+ | intronic |
| ADediting_1010053 | chr3_10833126_+ | intronic |
| ADediting_1010054 | chr3_10833131_+ | intronic |
| ADediting_1010055 | chr3_10833174_+ | intronic |
| ADediting_1010056 | chr3_10833187_+ | intronic |
| ADediting_1010057 | chr3_10833201_+ | intronic |
| ADediting_1010058 | chr3_10833242_+ | intronic |
| ADediting_1010059 | chr3_10833245_+ | intronic |
| ADediting_1010090 | chr3_10886636_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_1010041 | chr3_10824946_+ | SINE | Alu | Name=AluSx |
| ADediting_1010042 | chr3_10824964_+ | SINE | Alu | Name=AluSx |
| ADediting_1010043 | chr3_10824983_+ | SINE | Alu | Name=AluSx |
| ADediting_1010044 | chr3_10825025_+ | SINE | Alu | Name=AluSx |
| ADediting_1010045 | chr3_10825061_+ | SINE | Alu | Name=AluSx |
| ADediting_1010046 | chr3_10825062_+ | SINE | Alu | Name=AluSx |
| ADediting_1010047 | chr3_10825075_+ | SINE | Alu | Name=AluSx |
| ADediting_1010048 | chr3_10825085_+ | SINE | Alu | Name=AluSx |
| ADediting_1010049 | chr3_10825102_+ | SINE | Alu | Name=AluSx |
| ADediting_1010050 | chr3_10825103_+ | SINE | Alu | Name=AluSx |
| ADediting_1010051 | chr3_10825117_+ | SINE | Alu | Name=AluSx |
| ADediting_1010052 | chr3_10833118_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1010053 | chr3_10833126_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1010054 | chr3_10833131_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1010055 | chr3_10833174_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1010056 | chr3_10833187_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1010057 | chr3_10833201_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1010058 | chr3_10833242_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1010059 | chr3_10833245_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1010090 | chr3_10886636_+ | SINE | Alu | Name=AluSq |
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RNA A-to-I editing events in the alternative splicing sites for SLC6A11 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SLC6A11 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |