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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for SLC6A11 |
 Gene summary |
| Gene information | Gene symbol | SLC6A11 | Gene ID | 6538 |
| Gene name | solute carrier family 6 member 11 | |
| Synonyms | GAT-3|GAT3|GAT4 | |
| Cytomap | 3p25.3 | |
| Type of gene | protein-coding | |
| Description | sodium- and chloride-dependent GABA transporter 3GABA transporter 3solute carrier family 6 (neurotransmitter transporter), member 11solute carrier family 6 (neurotransmitter transporter, GABA), member 11 | |
| Modification date | 20200313 | |
| UniProtAcc | P48066, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for SLC6A11 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_1010041(10824946, +), ADediting_1010042(10824964, +), ADediting_1010043(10824983, +), ADediting_1010044(10825025, +), ADediting_1010045(10825061, +), ADediting_1010046(10825062, +), ADediting_1010047(10825075, +), ADediting_1010048(10825085, +), ADediting_1010049(10825102, +), ADediting_1010050(10825103, +), ADediting_1010051(10825117, +), ADediting_1010052(10833118, +), ADediting_1010053(10833126, +), ADediting_1010054(10833131, +), ADediting_1010055(10833174, +), ADediting_1010056(10833187, +), ADediting_1010057(10833201, +), ADediting_1010058(10833242, +), ADediting_1010059(10833245, +), ADediting_1010090(10886636, +), |
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RNA editing positional annotations for SLC6A11 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_1010041 | chr3_10824946_+ | UTR3 |
| ADediting_1010042 | chr3_10824964_+ | UTR3 |
| ADediting_1010043 | chr3_10824983_+ | UTR3 |
| ADediting_1010044 | chr3_10825025_+ | UTR3 |
| ADediting_1010045 | chr3_10825061_+ | UTR3 |
| ADediting_1010046 | chr3_10825062_+ | UTR3 |
| ADediting_1010047 | chr3_10825075_+ | UTR3 |
| ADediting_1010048 | chr3_10825085_+ | UTR3 |
| ADediting_1010049 | chr3_10825102_+ | UTR3 |
| ADediting_1010050 | chr3_10825103_+ | UTR3 |
| ADediting_1010051 | chr3_10825117_+ | UTR3 |
| ADediting_1010052 | chr3_10833118_+ | intronic |
| ADediting_1010053 | chr3_10833126_+ | intronic |
| ADediting_1010054 | chr3_10833131_+ | intronic |
| ADediting_1010055 | chr3_10833174_+ | intronic |
| ADediting_1010056 | chr3_10833187_+ | intronic |
| ADediting_1010057 | chr3_10833201_+ | intronic |
| ADediting_1010058 | chr3_10833242_+ | intronic |
| ADediting_1010059 | chr3_10833245_+ | intronic |
| ADediting_1010090 | chr3_10886636_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_1010041 | chr3_10824946_+ | SINE | Alu | Name=AluSx |
| ADediting_1010042 | chr3_10824964_+ | SINE | Alu | Name=AluSx |
| ADediting_1010043 | chr3_10824983_+ | SINE | Alu | Name=AluSx |
| ADediting_1010044 | chr3_10825025_+ | SINE | Alu | Name=AluSx |
| ADediting_1010045 | chr3_10825061_+ | SINE | Alu | Name=AluSx |
| ADediting_1010046 | chr3_10825062_+ | SINE | Alu | Name=AluSx |
| ADediting_1010047 | chr3_10825075_+ | SINE | Alu | Name=AluSx |
| ADediting_1010048 | chr3_10825085_+ | SINE | Alu | Name=AluSx |
| ADediting_1010049 | chr3_10825102_+ | SINE | Alu | Name=AluSx |
| ADediting_1010050 | chr3_10825103_+ | SINE | Alu | Name=AluSx |
| ADediting_1010051 | chr3_10825117_+ | SINE | Alu | Name=AluSx |
| ADediting_1010052 | chr3_10833118_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1010053 | chr3_10833126_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1010054 | chr3_10833131_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1010055 | chr3_10833174_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1010056 | chr3_10833187_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1010057 | chr3_10833201_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1010058 | chr3_10833242_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1010059 | chr3_10833245_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1010090 | chr3_10886636_+ | SINE | Alu | Name=AluSq |
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RNA A-to-I editing events in the alternative splicing sites for SLC6A11 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SLC6A11 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for SLC6A11 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for SLC6A11 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1010041 | chr3_10824946_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-150-5p | chr3 | 10824939 | 10824945 | 7mer-m8 | 10824925 | 10824946 | 140 | -15.8 |
| ADediting_1010041 | chr3_10824946_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-6778-3p | chr3 | 10824941 | 10824947 | 7mer-m8 | 10824928 | 10824948 | 143 | -13.97 |
| ADediting_1010046 | chr3_10825062_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-10394-5p | chr3 | 10825055 | 10825061 | 7mer-m8 | 10825039 | 10825062 | 147 | -21.64 |
| ADediting_1010046 | chr3_10825062_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-1205 | chr3 | 10825055 | 10825061 | 7mer-m8 | 10825043 | 10825062 | 140 | -14.05 |
| ADediting_1010046 | chr3_10825062_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-3672 | chr3 | 10825060 | 10825066 | 7mer-m8 | 10825042 | 10825067 | 154 | -16.2 |
| ADediting_1010046 | chr3_10825062_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-4418 | chr3 | 10825056 | 10825062 | 7mer-m8 | 10825046 | 10825063 | 152 | -15.81 |
| ADediting_1010046 | chr3_10825062_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-509-3-5p | chr3 | 10825056 | 10825062 | 7mer-m8 | 10825044 | 10825063 | 161 | -21.02 |
| ADediting_1010046 | chr3_10825062_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-509-5p | chr3 | 10825056 | 10825062 | 7mer-m8 | 10825043 | 10825063 | 151 | -15.98 |
| ADediting_1010046 | chr3_10825062_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-6864-3p | chr3 | 10825060 | 10825066 | 7mer-m8 | 10825047 | 10825067 | 142 | -11.29 |
| ADediting_1010046 | chr3_10825062_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-873-3p | chr3 | 10825059 | 10825066 | 8mer-1a | 10825044 | 10825066 | 141 | -17.33 |
| ADediting_1010048 | chr3_10825085_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-6747-3p | chr3 | 10825083 | 10825090 | 8mer-1a | 10825068 | 10825090 | 149 | -23.73 |
| ADediting_1010049 | chr3_10825102_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-9900 | chr3 | 10825100 | 10825106 | 7mer-m8 | 10825088 | 10825107 | 155 | -17.1 |
| ADediting_1010050 | chr3_10825103_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-3155a | chr3 | 10825100 | 10825106 | 7mer-m8 | 10825089 | 10825107 | 145 | -24.35 |
| ADediting_1010050 | chr3_10825103_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-3155b | chr3 | 10825100 | 10825106 | 7mer-m8 | 10825092 | 10825107 | 145 | -23.45 |
| ADediting_1010050 | chr3_10825103_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-484 | chr3 | 10825100 | 10825106 | 7mer-m8 | 10825084 | 10825107 | 150 | -23.63 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1010042 | chr3_10824964_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-125a-3p | chr3 | 10824961 | 10824968 | 8mer-1a | 10824947 | 10824968 | 140 | -19.94 |
| ADediting_1010043 | chr3_10824983_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-371a-5p | chr3 | 10824977 | 10824984 | 8mer-1a | 10824965 | 10824984 | 146 | -15.86 |
| ADediting_1010043 | chr3_10824983_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-6843-3p | chr3 | 10824981 | 10824987 | 7mer-m8 | 10824969 | 10824988 | 152 | -20.48 |
| ADediting_1010043 | chr3_10824983_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-6848-3p | chr3 | 10824981 | 10824987 | 7mer-m8 | 10824971 | 10824988 | 142 | -15.32 |
| ADediting_1010045 | chr3_10825061_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-5186 | chr3 | 10825059 | 10825066 | 8mer-1a | 10825043 | 10825066 | 149 | -13.88 |
| ADediting_1010045 | chr3_10825061_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-6511b-5p | chr3 | 10825054 | 10825061 | 8mer-1a | 10825037 | 10825061 | 153 | -17.97 |
| ADediting_1010045 | chr3_10825061_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-6811-5p | chr3 | 10825054 | 10825061 | 8mer-1a | 10825039 | 10825061 | 150 | -17.05 |
| ADediting_1010046 | chr3_10825062_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-5186 | chr3 | 10825059 | 10825066 | 8mer-1a | 10825043 | 10825066 | 149 | -13.88 |
| ADediting_1010047 | chr3_10825075_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-1200 | chr3 | 10825071 | 10825077 | 7mer-m8 | 10825057 | 10825078 | 140 | -19.43 |
| ADediting_1010047 | chr3_10825075_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-6869-5p | chr3 | 10825068 | 10825074 | 7mer-m8 | 10825051 | 10825075 | 145 | -20.58 |
| ADediting_1010048 | chr3_10825085_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-3977 | chr3 | 10825081 | 10825087 | 7mer-m8 | 10825066 | 10825088 | 145 | -12.04 |
| ADediting_1010051 | chr3_10825117_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-891b | chr3 | 10825115 | 10825122 | 8mer-1a | 10825101 | 10825122 | 142 | -15.49 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-5688 | chr3 | 10825443 | 10825449 | 7mer-m8 | 10825425 | 10825450 | 148 | -11.8 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000132164.10 | ENST00000254488.7 | SLC6A11-201 | hsa-miR-589-3p | chr3 | 10940060 | 10940066 | 7mer-m8 | 10940042 | 10940067 | 154 | -18.92 |
| ADediting_1337758 | chr7_5495892_- | ENSG00000132164.10 | ENST00000254488.7 | SLC6A11-201 | hsa-miR-589-5p | chr3 | 10939946 | 10939953 | 8mer-1a | 10939932 | 10939953 | 140 | -15.45 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000132164.10 | ENST00000254488.7 | SLC6A11-201 | hsa-miR-4477b | chr3 | 10939230 | 10939237 | 8mer-1a | 10939216 | 10939237 | 142 | -9.29 |
| ADediting_1535953 | chr14_101045971_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-381-3p | chr3 | 10824546 | 10824553 | 8mer-1a | 10824534 | 10824553 | 151 | -16.45 |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-381-3p | chr3 | 10824181 | 10824188 | 8mer-1a | 10824167 | 10824188 | 140 | -15.19 |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-381-3p | chr3 | 10824268 | 10824274 | 7mer-m8 | 10824258 | 10824275 | 150 | -16.51 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000132164.10 | ENST00000254488.7 | SLC6A11-201 | hsa-miR-641 | chr3 | 10938798 | 10938804 | 7mer-m8 | 10938784 | 10938805 | 153 | -20.62 |
| ADediting_1596844 | chr1_162342605_+ | ENSG00000132164.10 | ENST00000254488.7 | SLC6A11-201 | hsa-miR-556-3p | chr3 | 10939135 | 10939142 | 8mer-1a | 10939121 | 10939142 | 155 | -11.21 |
| ADediting_496066 | chr15_66496985_- | ENSG00000132164.10 | ENST00000254488.7 | SLC6A11-201 | hsa-miR-4512 | chr3 | 10938950 | 10938956 | 7mer-m8 | 10938935 | 10938957 | 142 | -21.78 |
| ADediting_496066 | chr15_66496985_- | ENSG00000132164.10 | ENST00000254488.7 | SLC6A11-201 | hsa-miR-4512 | chr3 | 10940299 | 10940306 | 8mer-1a | 10940286 | 10940306 | 143 | -17.49 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000132164.10 | ENST00000254488.7 | SLC6A11-201 | hsa-miR-4775 | chr3 | 10939185 | 10939192 | 8mer-1a | 10939171 | 10939192 | 140 | -9.8 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000132164.10 | ENST00000254488.7 | SLC6A11-201 | hsa-miR-5585-3p | chr3 | 10940419 | 10940425 | 7mer-m8 | 10940406 | 10940426 | 141 | -10.7 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-5688 | chr3 | 10824216 | 10824222 | 7mer-m8 | 10824204 | 10824223 | 149 | -13.26 |
| ADediting_1337758 | chr7_5495892_- | ENSG00000132164.10 | ENST00000254488.7 | SLC6A11-201 | hsa-miR-589-5p | chr3 | 10940338 | 10940344 | 7mer-m8 | 10940324 | 10940345 | 140 | -11.69 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000132164.10 | ENST00000254488.7 | SLC6A11-201 | hsa-miR-641 | chr3 | 10939468 | 10939475 | 8mer-1a | 10939452 | 10939475 | 151 | -15.07 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000132164.10 | ENST00000254488.7 | SLC6A11-201 | hsa-miR-641 | chr3 | 10939468 | 10939475 | 8mer-1a | 10939452 | 10939475 | 151 | -15.07 |
| ADediting_286380 | chr11_79422188_- | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-5579-3p | chr3 | 10823716 | 10823723 | 8mer-1a | 10823703 | 10823723 | 145 | -12.44 |
| ADediting_291761 | chr11_93733708_- | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-1304-3p | chr3 | 10825121 | 10825127 | 7mer-m8 | 10825106 | 10825128 | 155 | -21.84 |
| ADediting_496066 | chr15_66496985_- | ENSG00000132164.10 | ENST00000254488.7 | SLC6A11-201 | hsa-miR-4512 | chr3 | 10939532 | 10939538 | 7mer-m8 | 10939518 | 10939539 | 142 | -14.03 |
| ADediting_527135 | chr16_24203190_+ | ENSG00000132164.10 | ENST00000254488.7 | SLC6A11-201 | hsa-miR-1273h-3p | chr3 | 10940038 | 10940045 | 8mer-1a | 10940024 | 10940045 | 145 | -14.04 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000132164.10 | ENST00000254488.7 | SLC6A11-201 | hsa-miR-4775 | chr3 | 10940691 | 10940698 | 8mer-1a | 10940677 | 10940698 | 145 | -4.35 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-4775 | chr3 | 10824873 | 10824879 | 7mer-m8 | 10824859 | 10824880 | 153 | -5.98 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000132164.10 | ENST00000454147.1 | SLC6A11-202 | hsa-miR-4775 | chr3 | 10824890 | 10824896 | 7mer-1a | 10824875 | 10824896 | 144 | -7.9 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for SLC6A11 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000454147.1 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_1010041 | ENST00000454147.1 | chr3_10824946_+ | 2242 | -923.70 | -924.00 | -926.00 |
| ADediting_1010042 | ENST00000454147.1 | chr3_10824964_+ | 2260 | -924.20 | -924.00 | -926.00 |
| ADediting_1010043 | ENST00000454147.1 | chr3_10824983_+ | 2279 | -925.10 | -924.00 | -926.00 |
| ADediting_1010044 | ENST00000454147.1 | chr3_10825025_+ | 2321 | -924.00 | -924.00 | -926.00 |
| ADediting_1010045 | ENST00000454147.1 | chr3_10825061_+ | 2357 | -924.40 | -924.00 | -926.00 |
| ADediting_1010046 | ENST00000454147.1 | chr3_10825062_+ | 2358 | -921.60 | -924.00 | -926.00 |
| ADediting_1010047 | ENST00000454147.1 | chr3_10825075_+ | 2371 | -924.60 | -924.00 | -926.00 |
| ADediting_1010048 | ENST00000454147.1 | chr3_10825085_+ | 2381 | -927.70 | -924.00 | -926.00 |
| ADediting_1010049 | ENST00000454147.1 | chr3_10825102_+ | 2398 | -924.00 | -924.00 | -926.00 |
| ADediting_1010050 | ENST00000454147.1 | chr3_10825103_+ | 2399 | -924.30 | -924.00 | -926.00 |
| ADediting_1010051 | ENST00000454147.1 | chr3_10825117_+ | 2413 | -924.00 | -924.00 | -926.00 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for SLC6A11 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_1010050 | chr3_10825103_+ | 0.806862298192211 | -0.0139409388159432 | 0.0784947017860453 | -0.100085448794582 | 1.97107880954382e-08 | 0.312141721568218 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 2.86248041235658e-10 | 0.348290309263487 | 0.000101870737823936 | 0.218916506418409 | 5.5814896607195e-20 | 0.48830251816879 |
| AC | 3.64591876326408e-39 | 0.706868270309161 | 1.13013128975038e-19 | 0.532043524204834 | 2.78781871451943e-20 | 0.539481187614394 |
| PCC | 1.60659224838271e-07 | 0.368161023533804 | 0.00033013003263852 | 0.257101312491732 | 3.99994257303511e-07 | 0.356964368289113 |
| CER | 0.637975593773595 | 0.0387282674544538 | 0.0165639471226757 | -0.195397492312572 | 8.79836615944385e-05 | 0.314653156422168 |
| FP | 0.00598612566897046 | 0.205259703166549 | 0.233636638299012 | 0.0897244137517669 | 4.94585277080149e-07 | 0.366293244856916 |
| IFG | 2.45376094907757e-05 | 0.738953409838884 | 9.68449090433942e-06 | 0.761797299990382 | 0.0953332175406372 | 0.340956550736814 |
| PG | 8.7484451820155e-09 | 0.406259917253698 | 0.00165204157553988 | 0.229183112117834 | 0.414241674792019 | 0.0602167537564705 |
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Relation with AD stages for SLC6A11 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| TCX | 3.88342528467932e-06 | 0.431457240479204 |
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RelatedDrugs for SLC6A11 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for SLC6A11 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| SLC6A11 | C0025202 | melanoma | 1 | CTD_human |
| SLC6A11 | C0036341 | Schizophrenia | 1 | PSYGENET |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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