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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for FAM160B2 |
 Gene summary |
| Gene information | Gene symbol | FAM160B2 | Gene ID | 64760 |
| Gene name | family with sequence similarity 160 member B2 | |
| Synonyms | RAI16 | |
| Cytomap | 8p21.3 | |
| Type of gene | protein-coding | |
| Description | protein FAM160B2retinoic acid induced 16retinoic acid-induced protein 16 | |
| Modification date | 20200313 | |
| UniProtAcc | Q86V87, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for FAM160B2 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_1396387(22090673, +), ADediting_1396388(22090678, +), ADediting_1396389(22090704, +), ADediting_1396390(22090754, +), ADediting_1396391(22090764, +), ADediting_1396392(22090766, +), ADediting_1396393(22090785, +), ADediting_1396394(22090790, +), ADediting_1396395(22090799, +), ADediting_1396396(22090814, +), ADediting_1396397(22090834, +), ADediting_1396398(22090880, +), ADediting_1396399(22090892, +), ADediting_1396400(22090898, +), ADediting_1396401(22091316, +), ADediting_1396402(22091321, +), ADediting_1396403(22091331, +), ADediting_1396404(22091332, +), ADediting_1396405(22091344, +), ADediting_1396406(22091373, +), ADediting_1396407(22091383, +), ADediting_1396408(22091405, +), ADediting_1396409(22091409, +), ADediting_1396410(22091412, +), ADediting_1396411(22091419, +), ADediting_1396412(22091424, +), ADediting_1396413(22091427, +), ADediting_1396414(22091434, +), ADediting_1396415(22091453, +), ADediting_1396416(22091483, +), ADediting_1396417(22091505, +), ADediting_1396418(22091506, +), ADediting_1396419(22091512, +), ADediting_1396420(22092324, +), ADediting_1396421(22092325, +), ADediting_1396422(22092330, +), ADediting_1396423(22092370, +), ADediting_1396424(22092381, +), ADediting_1396425(22092384, +), ADediting_1396426(22092393, +), ADediting_1396427(22092394, +), ADediting_1396428(22092404, +), ADediting_1396429(22092424, +), ADediting_1396430(22092427, +), ADediting_1396431(22092429, +), ADediting_1396432(22092430, +), ADediting_1396433(22092433, +), ADediting_1396434(22092437, +), ADediting_1396435(22092449, +), ADediting_1396436(22092459, +), ADediting_1396437(22092460, +), ADediting_1396438(22092465, +), ADediting_1396439(22092468, +), ADediting_1396440(22092469, +), ADediting_1396441(22092495, +), ADediting_1396442(22092503, +), ADediting_1396443(22092513, +), ADediting_1396444(22092515, +), ADediting_1396445(22092534, +), ADediting_1396446(22093835, +), ADediting_1396447(22093844, +), ADediting_1396448(22093907, +), ADediting_1590186(22090728, +), ADediting_1590187(22090780, +), ADediting_1590188(22091385, +), ADediting_1590189(22092418, +), ADediting_1590190(22093781, +), ADediting_1590191(22093937, +), |
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RNA editing positional annotations for FAM160B2 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_1396387 | chr8_22090673_+ | intronic |
| ADediting_1396388 | chr8_22090678_+ | intronic |
| ADediting_1396389 | chr8_22090704_+ | intronic |
| ADediting_1396390 | chr8_22090754_+ | intronic |
| ADediting_1396391 | chr8_22090764_+ | intronic |
| ADediting_1396392 | chr8_22090766_+ | intronic |
| ADediting_1396393 | chr8_22090785_+ | intronic |
| ADediting_1396394 | chr8_22090790_+ | intronic |
| ADediting_1396395 | chr8_22090799_+ | intronic |
| ADediting_1396396 | chr8_22090814_+ | intronic |
| ADediting_1396397 | chr8_22090834_+ | intronic |
| ADediting_1396398 | chr8_22090880_+ | intronic |
| ADediting_1396399 | chr8_22090892_+ | intronic |
| ADediting_1396400 | chr8_22090898_+ | intronic |
| ADediting_1396401 | chr8_22091316_+ | intronic |
| ADediting_1396402 | chr8_22091321_+ | intronic |
| ADediting_1396403 | chr8_22091331_+ | intronic |
| ADediting_1396404 | chr8_22091332_+ | intronic |
| ADediting_1396405 | chr8_22091344_+ | intronic |
| ADediting_1396406 | chr8_22091373_+ | intronic |
| ADediting_1396407 | chr8_22091383_+ | intronic |
| ADediting_1396408 | chr8_22091405_+ | intronic |
| ADediting_1396409 | chr8_22091409_+ | intronic |
| ADediting_1396410 | chr8_22091412_+ | intronic |
| ADediting_1396411 | chr8_22091419_+ | intronic |
| ADediting_1396412 | chr8_22091424_+ | intronic |
| ADediting_1396413 | chr8_22091427_+ | intronic |
| ADediting_1396414 | chr8_22091434_+ | intronic |
| ADediting_1396415 | chr8_22091453_+ | intronic |
| ADediting_1396416 | chr8_22091483_+ | intronic |
| ADediting_1396417 | chr8_22091505_+ | intronic |
| ADediting_1396418 | chr8_22091506_+ | intronic |
| ADediting_1396419 | chr8_22091512_+ | intronic |
| ADediting_1396420 | chr8_22092324_+ | intronic |
| ADediting_1396421 | chr8_22092325_+ | intronic |
| ADediting_1396422 | chr8_22092330_+ | intronic |
| ADediting_1396423 | chr8_22092370_+ | intronic |
| ADediting_1396424 | chr8_22092381_+ | intronic |
| ADediting_1396425 | chr8_22092384_+ | intronic |
| ADediting_1396426 | chr8_22092393_+ | intronic |
| ADediting_1396427 | chr8_22092394_+ | intronic |
| ADediting_1396428 | chr8_22092404_+ | intronic |
| ADediting_1396429 | chr8_22092424_+ | intronic |
| ADediting_1396430 | chr8_22092427_+ | intronic |
| ADediting_1396431 | chr8_22092429_+ | intronic |
| ADediting_1396432 | chr8_22092430_+ | intronic |
| ADediting_1396433 | chr8_22092433_+ | intronic |
| ADediting_1396434 | chr8_22092437_+ | intronic |
| ADediting_1396435 | chr8_22092449_+ | intronic |
| ADediting_1396436 | chr8_22092459_+ | intronic |
| ADediting_1396437 | chr8_22092460_+ | intronic |
| ADediting_1396438 | chr8_22092465_+ | intronic |
| ADediting_1396439 | chr8_22092468_+ | intronic |
| ADediting_1396440 | chr8_22092469_+ | intronic |
| ADediting_1396441 | chr8_22092495_+ | intronic |
| ADediting_1396442 | chr8_22092503_+ | intronic |
| ADediting_1396443 | chr8_22092513_+ | intronic |
| ADediting_1396444 | chr8_22092515_+ | intronic |
| ADediting_1396445 | chr8_22092534_+ | intronic |
| ADediting_1396446 | chr8_22093835_+ | intronic |
| ADediting_1396447 | chr8_22093844_+ | intronic |
| ADediting_1396448 | chr8_22093907_+ | intronic |
| ADediting_1590186 | chr8_22090728_+ | intronic |
| ADediting_1590187 | chr8_22090780_+ | intronic |
| ADediting_1590188 | chr8_22091385_+ | intronic |
| ADediting_1590189 | chr8_22092418_+ | intronic |
| ADediting_1590190 | chr8_22093781_+ | intronic |
| ADediting_1590191 | chr8_22093937_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_1396387 | chr8_22090673_+ | SINE | Alu | Name=AluJb |
| ADediting_1396388 | chr8_22090678_+ | SINE | Alu | Name=AluJb |
| ADediting_1396389 | chr8_22090704_+ | SINE | Alu | Name=AluJb |
| ADediting_1396390 | chr8_22090754_+ | SINE | Alu | Name=AluJb |
| ADediting_1396391 | chr8_22090764_+ | SINE | Alu | Name=AluJb |
| ADediting_1396392 | chr8_22090766_+ | SINE | Alu | Name=AluJb |
| ADediting_1396393 | chr8_22090785_+ | SINE | Alu | Name=AluJb |
| ADediting_1396394 | chr8_22090790_+ | SINE | Alu | Name=AluJb |
| ADediting_1396395 | chr8_22090799_+ | SINE | Alu | Name=AluJb |
| ADediting_1396396 | chr8_22090814_+ | SINE | Alu | Name=AluJb |
| ADediting_1396397 | chr8_22090834_+ | SINE | Alu | Name=AluJb |
| ADediting_1396398 | chr8_22090880_+ | SINE | Alu | Name=AluJb |
| ADediting_1396399 | chr8_22090892_+ | SINE | Alu | Name=AluJb |
| ADediting_1396400 | chr8_22090898_+ | SINE | Alu | Name=AluJb |
| ADediting_1396401 | chr8_22091316_+ | SINE | Alu | Name=AluSz |
| ADediting_1396402 | chr8_22091321_+ | SINE | Alu | Name=AluSz |
| ADediting_1396403 | chr8_22091331_+ | SINE | Alu | Name=AluSz |
| ADediting_1396404 | chr8_22091332_+ | SINE | Alu | Name=AluSz |
| ADediting_1396405 | chr8_22091344_+ | SINE | Alu | Name=AluSz |
| ADediting_1396406 | chr8_22091373_+ | SINE | Alu | Name=AluSz |
| ADediting_1396407 | chr8_22091383_+ | SINE | Alu | Name=AluSz |
| ADediting_1396408 | chr8_22091405_+ | SINE | Alu | Name=AluSz |
| ADediting_1396409 | chr8_22091409_+ | SINE | Alu | Name=AluSz |
| ADediting_1396410 | chr8_22091412_+ | SINE | Alu | Name=AluSz |
| ADediting_1396411 | chr8_22091419_+ | SINE | Alu | Name=AluSz |
| ADediting_1396412 | chr8_22091424_+ | SINE | Alu | Name=AluSz |
| ADediting_1396413 | chr8_22091427_+ | SINE | Alu | Name=AluSz |
| ADediting_1396414 | chr8_22091434_+ | SINE | Alu | Name=AluSz |
| ADediting_1396415 | chr8_22091453_+ | SINE | Alu | Name=AluSz |
| ADediting_1396416 | chr8_22091483_+ | SINE | Alu | Name=AluSz |
| ADediting_1396417 | chr8_22091505_+ | SINE | Alu | Name=AluSz |
| ADediting_1396418 | chr8_22091506_+ | SINE | Alu | Name=AluSz |
| ADediting_1396419 | chr8_22091512_+ | SINE | Alu | Name=AluSz |
| ADediting_1396420 | chr8_22092324_+ | SINE | Alu | Name=AluSz |
| ADediting_1396421 | chr8_22092325_+ | SINE | Alu | Name=AluSz |
| ADediting_1396422 | chr8_22092330_+ | SINE | Alu | Name=AluSz |
| ADediting_1396423 | chr8_22092370_+ | SINE | Alu | Name=AluSz |
| ADediting_1396424 | chr8_22092381_+ | SINE | Alu | Name=AluSz |
| ADediting_1396425 | chr8_22092384_+ | SINE | Alu | Name=AluSz |
| ADediting_1396426 | chr8_22092393_+ | SINE | Alu | Name=AluSz |
| ADediting_1396427 | chr8_22092394_+ | SINE | Alu | Name=AluSz |
| ADediting_1396428 | chr8_22092404_+ | SINE | Alu | Name=AluSz |
| ADediting_1396429 | chr8_22092424_+ | SINE | Alu | Name=AluSz |
| ADediting_1396430 | chr8_22092427_+ | SINE | Alu | Name=AluSz |
| ADediting_1396431 | chr8_22092429_+ | SINE | Alu | Name=AluSz |
| ADediting_1396432 | chr8_22092430_+ | SINE | Alu | Name=AluSz |
| ADediting_1396433 | chr8_22092433_+ | SINE | Alu | Name=AluSz |
| ADediting_1396434 | chr8_22092437_+ | SINE | Alu | Name=AluSz |
| ADediting_1396435 | chr8_22092449_+ | SINE | Alu | Name=AluSz |
| ADediting_1396436 | chr8_22092459_+ | SINE | Alu | Name=AluSz |
| ADediting_1396437 | chr8_22092460_+ | SINE | Alu | Name=AluSz |
| ADediting_1396438 | chr8_22092465_+ | SINE | Alu | Name=AluSz |
| ADediting_1396439 | chr8_22092468_+ | SINE | Alu | Name=AluSz |
| ADediting_1396440 | chr8_22092469_+ | SINE | Alu | Name=AluSz |
| ADediting_1396441 | chr8_22092495_+ | SINE | Alu | Name=AluSz |
| ADediting_1396442 | chr8_22092503_+ | SINE | Alu | Name=AluSz |
| ADediting_1396443 | chr8_22092513_+ | SINE | Alu | Name=AluSz |
| ADediting_1396444 | chr8_22092515_+ | SINE | Alu | Name=AluSz |
| ADediting_1396445 | chr8_22092534_+ | SINE | Alu | Name=AluSz |
| ADediting_1396446 | chr8_22093835_+ | SINE | Alu | Name=AluJb |
| ADediting_1396447 | chr8_22093844_+ | SINE | Alu | Name=AluJb |
| ADediting_1396448 | chr8_22093907_+ | SINE | Alu | Name=AluJb |
| ADediting_1590186 | chr8_22090728_+ | SINE | Alu | Name=AluJb |
| ADediting_1590187 | chr8_22090780_+ | SINE | Alu | Name=AluJb |
| ADediting_1590188 | chr8_22091385_+ | SINE | Alu | Name=AluSz |
| ADediting_1590189 | chr8_22092418_+ | SINE | Alu | Name=AluSz |
| ADediting_1590190 | chr8_22093781_+ | SINE | Alu | Name=AluJb |
| ADediting_1590191 | chr8_22093937_+ | SINE | Alu | Name=AluJb |
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RNA A-to-I editing events in the alternative splicing sites for FAM160B2 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for FAM160B2 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for FAM160B2 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for FAM160B2 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337757 | chr7_5495852_- | ENSG00000158863.22 | ENST00000289921.8 | FAM160B2-201 | hsa-miR-589-3p | chr8 | 22103476 | 22103482 | 7mer-m8 | 22103457 | 22103483 | 155 | -21.91 |
| ADediting_1596844 | chr1_162342605_+ | ENSG00000158863.22 | ENST00000289921.8 | FAM160B2-201 | hsa-miR-556-3p | chr8 | 22104808 | 22104814 | 7mer-m8 | 22104795 | 22104815 | 141 | -10.77 |
| ADediting_496066 | chr15_66496985_- | ENSG00000158863.22 | ENST00000289921.8 | FAM160B2-201 | hsa-miR-4512 | chr8 | 22103820 | 22103826 | 7mer-m8 | 22103806 | 22103827 | 140 | -14.13 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_291761 | chr11_93733708_- | ENSG00000158863.22 | ENST00000289921.8 | FAM160B2-201 | hsa-miR-1304-3p | chr8 | 22103333 | 22103340 | 8mer-1a | 22103321 | 22103340 | 149 | -20.33 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for FAM160B2 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for FAM160B2 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_1396389 | chr8_22090704_+ | 0.00391962612367861 | 0.234197797378303 | 4.11768218534487e-09 | 0.457061634175532 | 4.01197678483973e-07 | 0.399786558254538 |
| CER | ADediting_1396390 | chr8_22090754_+ | 0.00109016626549088 | 0.264137951820523 | 5.93648004594775e-10 | 0.478426375957485 | 2.95425979889315e-05 | 0.333995525709982 |
| CER | ADediting_1396391 | chr8_22090764_+ | 0.00335567774949493 | 0.238027985206775 | 7.34399651098484e-09 | 0.450383253637611 | 4.79391049321436e-05 | 0.325576358153258 |
| CER | ADediting_1396393 | chr8_22090785_+ | 0.001939563535271 | 0.251093133349353 | 4.6797086933119e-07 | 0.397662898691483 | 0.000576873989263014 | 0.277829355116804 |
| CER | ADediting_1396394 | chr8_22090790_+ | 0.00638617957820602 | 0.221755813423378 | 3.58472495157254e-08 | 0.431311496387307 | 6.21999143989126e-05 | 0.320942904599856 |
| CER | ADediting_1396395 | chr8_22090799_+ | 0.0610855451338973 | 0.153296921545611 | 0.000436717774155501 | 0.283602409711228 | 1.66022446843278e-05 | 0.343708889163125 |
| CER | ADediting_1396396 | chr8_22090814_+ | 0.00221225910888501 | 0.248019078660131 | 4.94692405156778e-09 | 0.454959380964546 | 0.000205340853874119 | 0.298662805507062 |
| CER | ADediting_1396397 | chr8_22090834_+ | 0.00816760923206344 | 0.215231626141406 | 5.30161418515649e-09 | 0.454162259012421 | 0.00103871154009339 | 0.265203381105014 |
| CER | ADediting_1396398 | chr8_22090880_+ | 0.00435784701490307 | 0.231550038415012 | 6.25815773924542e-07 | 0.393612822072645 | 0.0283382655599682 | 0.179071101729589 |
| DLPFC | ADediting_1396399 | chr8_22090892_+ | 0.211793164487576 | 0.071116014330016 | 0.606492002440624 | -0.0293673199771095 | 1.96962712354185e-08 | 0.312148447744128 |
| CER | ADediting_1396399 | chr8_22090892_+ | 0.000885237444302807 | 0.268695981924821 | 8.35052709225274e-12 | 0.520838679832543 | 0.000126662679216567 | 0.307890129864108 |
| CER | ADediting_1396401 | chr8_22091316_+ | 0.00616441121844601 | 0.222678502350013 | 1.82168549406989e-07 | 0.410451690318284 | 6.17945631117315e-06 | 0.359651656082169 |
| CER | ADediting_1396406 | chr8_22091373_+ | 0.00179483750315007 | 0.252888016717119 | 8.22257091922915e-09 | 0.449062028934069 | 6.57615746339915e-05 | 0.319942360698493 |
| CER | ADediting_1396407 | chr8_22091383_+ | 0.0135184873516083 | 0.20127468163437 | 1.28895631064129e-06 | 0.383304513600794 | 0.000195657298569969 | 0.299599310412198 |
| CER | ADediting_1396408 | chr8_22091405_+ | 0.00354072656157401 | 0.236711177742888 | 1.04383739554173e-07 | 0.417757102907957 | 0.000141103081571656 | 0.305854558577577 |
| CER | ADediting_1396409 | chr8_22091409_+ | 0.0136002088951949 | 0.201102514395357 | 2.99321225460905e-06 | 0.370822916848331 | 0.00114797819648875 | 0.262994470436681 |
| CER | ADediting_1396412 | chr8_22091424_+ | 0.00523194913085606 | 0.226914397545785 | 2.25969505700309e-06 | 0.375045394699929 | 6.71762011207854e-05 | 0.31955899174881 |
| CER | ADediting_1396413 | chr8_22091427_+ | 0.0212956953056134 | 0.187908611928837 | 5.50474220929321e-05 | 0.323125724851072 | 0.000522510765772164 | 0.279896538327479 |
| CER | ADediting_1396415 | chr8_22091453_+ | 0.0122373054400407 | 0.204100341740427 | 4.94873614148338e-05 | 0.325014831039841 | 0.00417653204155307 | 0.232615180186242 |
| CER | ADediting_1396416 | chr8_22091483_+ | 0.000623141210415853 | 0.27620692003694 | 1.03307901132989e-08 | 0.446376042464368 | 0.000367185501533237 | 0.287137839768013 |
| CER | ADediting_1396418 | chr8_22091506_+ | 0.00944096800952658 | 0.211303739418102 | 1.19652314983675e-06 | 0.384382490992362 | 0.00505803782453524 | 0.227778331968422 |
| DLPFC | ADediting_1396419 | chr8_22091512_+ | 0.00601893442107242 | 0.155681435779349 | 0.962373801292072 | 0.00269021946983034 | 3.11664060322811e-23 | 0.523710671661227 |
| CER | ADediting_1396419 | chr8_22091512_+ | 0.00233560379983315 | 0.246740290864884 | 8.35715292687066e-08 | 0.420626626316853 | 0.00101973681775321 | 0.265608508919347 |
| CER | ADediting_1396420 | chr8_22092324_+ | 0.000334375005443712 | 0.289027122385851 | 1.19512231113049e-10 | 0.495059541022188 | 0.00155723329384273 | 0.256142441720449 |
| CER | ADediting_1396421 | chr8_22092325_+ | 0.00260134209662085 | 0.244181131838166 | 1.75501237956991e-09 | 0.466650664130193 | 0.00230194047375676 | 0.247083106076639 |
| CER | ADediting_1396422 | chr8_22092330_+ | 0.00564966601129514 | 0.224939809951957 | 5.31967966337388e-10 | 0.479593658596138 | 1.3414451972751e-05 | 0.347222012021618 |
| DLPFC | ADediting_1396423 | chr8_22092370_+ | 0.0376907984827316 | 0.118097648335382 | 0.949841808516451 | -0.00358726872594642 | 6.04907033909473e-09 | 0.322717020379463 |
| CER | ADediting_1396423 | chr8_22092370_+ | 0.0887709053715611 | 0.139447698555406 | 2.22094671293803e-05 | 0.33884500858471 | 6.98464353989527e-05 | 0.318855515660298 |
| DLPFC | ADediting_1396425 | chr8_22092384_+ | 0.000654606823814845 | 0.192520665090479 | 0.335059850793997 | 0.0549305018440433 | 2.02562429016694e-11 | 0.368757952547925 |
| DLPFC | ADediting_1396427 | chr8_22092394_+ | 0.00464571280027149 | 0.160374692560947 | 0.925128408944501 | -0.00535907579562346 | 2.77715800340733e-17 | 0.455468907440941 |
| CER | ADediting_1396442 | chr8_22092503_+ | 0.0560694069167305 | 0.156338576371099 | 0.000117896320190078 | 0.309234257278298 | 0.0182399159676047 | 0.192554691501826 |
| CER | ADediting_1396443 | chr8_22092513_+ | 0.00493357938894211 | 0.228413071152728 | 1.83116442702082e-07 | 0.410382781061793 | 0.0118439506195851 | 0.205019984110962 |
| CER | ADediting_1396445 | chr8_22092534_+ | 0.000271917437940929 | 0.293154579038512 | 3.69430743764845e-11 | 0.506699558523081 | 0.00183578659058762 | 0.252367192831457 |
| CER | ADediting_1396448 | chr8_22093907_+ | 0.023104416993161 | 0.185423466708275 | 2.12796907080362e-06 | 0.375939899981791 | 0.0581491690398077 | 0.155051349978528 |
| CER | ADediting_1590187 | chr8_22090780_+ | 0.0417557907413546 | 0.166465130220536 | 0.000144138515248898 | 0.305451506501417 | 7.18001902223913e-05 | 0.318356576195264 |
| CER | ADediting_1590191 | chr8_22093937_+ | 0.00605107655215284 | 0.223161522807883 | 8.96203496132717e-07 | 0.388533170127091 | 0.350738119632036 | 0.0767215123804242 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 3.25909424277966e-24 | 0.533620151791113 | 6.142484579406e-28 | 0.568526621995808 | 1.51386068399815e-31 | 0.598794848451632 |
| AC | 5.77198910068815e-42 | 0.724516194221095 | 7.76804525478129e-30 | 0.636808543913342 | 7.61669013887826e-25 | 0.5900703061698 |
| PCC | 1.06077595398764e-22 | 0.632093182662292 | 2.91073629388301e-20 | 0.602577157968763 | 1.90302538587769e-08 | 0.392804470153053 |
| CER | 1.83156973627636e-07 | 0.410379842188274 | 2.8374420579171e-12 | 0.53070845743281 | 0.00013499116900595 | 0.306691246192601 |
| TCX | 9.16235567322606e-09 | 0.447791393239136 | 0.00881901337096366 | 0.213159504867819 | 4.7234538609342e-11 | 0.50429913943459 |
| FP | 2.45516780929081e-08 | 0.402952567914574 | 0.169169100200631 | 0.103503720868816 | 3.04647084844375e-11 | 0.47158459020834 |
| IFG | 5.59771916510371e-05 | 0.716543480279094 | 0.000187115882654301 | 0.679516238083381 | 0.00153848153948384 | 0.599520358908389 |
| PG | 0.864985717001078 | -0.0125514033339264 | 0.841456948319139 | 0.0147656674372726 | 1.03176901223845e-06 | 0.349231436859006 |
| STG | 0.00473525853656692 | 0.305357871049407 | 0.762810979513352 | -0.0334197139735192 | 1.17214739618767e-07 | 0.539712170110652 |
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Relation with AD stages for FAM160B2 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_1396389 | chr8_22090704_+ | 4.17975652890541e-05 | 0.383539369514451 |
| CER | ADediting_1396396 | chr8_22090814_+ | 0.000799002708053708 | 0.31794070297689 |
| CER | ADediting_1396397 | chr8_22090834_+ | 3.28822523189227e-05 | 0.388299643510887 |
| CER | ADediting_1396399 | chr8_22090892_+ | 1.91565540303312e-05 | 0.398759493429288 |
| CER | ADediting_1396409 | chr8_22091409_+ | 0.00114974871504058 | 0.308746455779115 |
| CER | ADediting_1396419 | chr8_22091512_+ | 0.00138481270947038 | 0.30393150417578 |
| CER | ADediting_1396420 | chr8_22092324_+ | 0.000116677774190888 | 0.362293580247461 |
| CER | ADediting_1396421 | chr8_22092325_+ | 0.000557671872837432 | 0.326749235783875 |
| CER | ADediting_1396422 | chr8_22092330_+ | 5.08184715244333e-05 | 0.37960671399737 |
| CER | ADediting_1396423 | chr8_22092370_+ | 0.00134820484462551 | 0.304629946154963 |
| CER | ADediting_1396445 | chr8_22092534_+ | 9.09565846367866e-05 | 0.367584624936303 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 1.56380345906848e-07 | 0.479062916616177 |
| TCX | 0.000133428475508939 | 0.362623538650434 |
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RelatedDrugs for FAM160B2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for FAM160B2 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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