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Center for Computational Systems Medicine
Soverview

Gene summary

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RNA A-to-I events

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Differntial gene expression between RNA A-to-I edited versus non-edited samples

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Protein coding region RNA A-to-I editings

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The effects of the RNA editing to the miRNA binding sites

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The effects of the RNA editing to the stability of the RNA structures

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Relation with ADAR

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Relation with AD stages

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Related drugs with this gene

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Related diseases with this gene


Gene summary for NIPBL-DT

check button Gene summary
Gene informationGene symbol

NIPBL-DT

Gene ID

646719

Gene nameNIPBL divergent transcript
SynonymsNIPBL-AS|NIPBL-AS1
Cytomap

5p13.2

Type of genencRNA
DescriptionNIPBL antisense RNA 1 (head to head)
Modification date20200313
UniProtAcc

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for NIPBL-DT

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_1200314(36868326, -), ADediting_1200315(36868327, -), ADediting_1200316(36868362, -), ADediting_1200317(36868369, -), ADediting_1200318(36868375, -), ADediting_1200319(36868473, -), ADediting_1200320(36868508, -), ADediting_1200321(36868509, -), ADediting_1200322(36868517, -), ADediting_1200323(36868522, -), ADediting_1200324(36869000, -), ADediting_1200325(36869004, -), ADediting_1200326(36869005, -), ADediting_1200327(36872403, -), ADediting_1200328(36872458, -), ADediting_1200329(36872480, -), ADediting_1200330(36872483, -), ADediting_1200331(36872525, -), ADediting_1200332(36872538, -), ADediting_1200333(36872583, -), ADediting_1200334(36872599, -), ADediting_1200335(36872600, -), ADediting_1200336(36872608, -), ADediting_1581451(36865960, -), ADediting_1581452(36865982, -), ADediting_1581453(36867124, -), ADediting_1581454(36867143, -), ADediting_1581455(36867234, -), ADediting_1581456(36872535, -),

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RNA editing positional annotations for NIPBL-DT using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_1200314chr5_36868326_-ncRNA_intronic
ADediting_1200315chr5_36868327_-ncRNA_intronic
ADediting_1200316chr5_36868362_-ncRNA_intronic
ADediting_1200317chr5_36868369_-ncRNA_intronic
ADediting_1200318chr5_36868375_-ncRNA_intronic
ADediting_1200319chr5_36868473_-ncRNA_intronic
ADediting_1200320chr5_36868508_-ncRNA_intronic
ADediting_1200321chr5_36868509_-ncRNA_intronic
ADediting_1200322chr5_36868517_-ncRNA_intronic
ADediting_1200323chr5_36868522_-ncRNA_intronic
ADediting_1200324chr5_36869000_-ncRNA_intronic
ADediting_1200325chr5_36869004_-ncRNA_intronic
ADediting_1200326chr5_36869005_-ncRNA_intronic
ADediting_1200327chr5_36872403_-ncRNA_exonic
ADediting_1200328chr5_36872458_-ncRNA_exonic
ADediting_1200329chr5_36872480_-ncRNA_exonic
ADediting_1200330chr5_36872483_-ncRNA_exonic
ADediting_1200331chr5_36872525_-ncRNA_exonic
ADediting_1200332chr5_36872538_-ncRNA_exonic
ADediting_1200333chr5_36872583_-ncRNA_exonic
ADediting_1200334chr5_36872599_-ncRNA_exonic
ADediting_1200335chr5_36872600_-ncRNA_exonic
ADediting_1200336chr5_36872608_-ncRNA_exonic
ADediting_1581451chr5_36865960_-ncRNA_exonic
ADediting_1581452chr5_36865982_-ncRNA_exonic
ADediting_1581453chr5_36867124_-ncRNA_exonic
ADediting_1581454chr5_36867143_-ncRNA_exonic
ADediting_1581455chr5_36867234_-ncRNA_exonic
ADediting_1581456chr5_36872535_-ncRNA_exonic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_1200314chr5_36868326_-SINEAluName=AluY
ADediting_1200315chr5_36868327_-SINEAluName=AluY
ADediting_1200316chr5_36868362_-SINEAluName=AluY
ADediting_1200317chr5_36868369_-SINEAluName=AluY
ADediting_1200318chr5_36868375_-SINEAluName=AluY
ADediting_1200319chr5_36868473_-SINEAluName=AluY
ADediting_1200320chr5_36868508_-SINEAluName=AluY
ADediting_1200321chr5_36868509_-SINEAluName=AluY
ADediting_1200322chr5_36868517_-SINEAluName=AluY
ADediting_1200323chr5_36868522_-SINEAluName=AluY
ADediting_1200324chr5_36869000_-SINEAluName=FLAM_C
ADediting_1200325chr5_36869004_-SINEAluName=FLAM_C
ADediting_1200326chr5_36869005_-SINEAluName=FLAM_C
ADediting_1200327chr5_36872403_-SINEAluName=AluY
ADediting_1200328chr5_36872458_-SINEAluName=AluY
ADediting_1200329chr5_36872480_-SINEAluName=AluY
ADediting_1200330chr5_36872483_-SINEAluName=AluY
ADediting_1200331chr5_36872525_-SINEAluName=AluY
ADediting_1200332chr5_36872538_-SINEAluName=AluY
ADediting_1200333chr5_36872583_-SINEAluName=AluY
ADediting_1200334chr5_36872599_-SINEAluName=AluY
ADediting_1200335chr5_36872600_-SINEAluName=AluY
ADediting_1200336chr5_36872608_-SINEAluName=AluY
ADediting_1581451chr5_36865960_-SINEAluName=AluJr
ADediting_1581452chr5_36865982_-SINEAluName=AluJr
ADediting_1581453chr5_36867124_-SINEAluName=AluSz
ADediting_1581454chr5_36867143_-SINEAluName=AluSz
ADediting_1581455chr5_36867234_-SINEAluName=AluSz
ADediting_1581456chr5_36872535_-SINEAluName=AluY

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RNA A-to-I editing events in the alternative splicing sites for NIPBL-DT

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for NIPBL-DT

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs