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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for RPL23AP53

check button Gene summary
Gene informationGene symbol

RPL23AP53

Gene ID

644128

Gene nameribosomal protein L23a pseudogene 53
SynonymsRPL23A_20_869
Cytomap

8p23.3

Type of genepseudo
Description-
Modification date20200313
UniProtAcc

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for RPL23AP53

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_1397032(225703, -), ADediting_1397053(225831, -), ADediting_1397054(225832, -), ADediting_1397058(225854, -), ADediting_1397059(225901, -), ADediting_1397084(225934, -), ADediting_1397102(226029, -), ADediting_1397103(226035, -), ADediting_1397104(226049, -), ADediting_1397105(226089, -), ADediting_1397116(226096, -), ADediting_1397117(226097, -), ADediting_1397118(226101, -), ADediting_1397126(226162, -), ADediting_1397127(226163, -), ADediting_1397129(226169, -), ADediting_1397133(226182, -), ADediting_1397134(226183, -), ADediting_1397135(226214, -), ADediting_1397136(226288, -), ADediting_1397137(226310, -), ADediting_1397145(226324, -), ADediting_1397146(226328, -), ADediting_1397161(226334, -), ADediting_1397162(226347, -), ADediting_1397163(226402, -), ADediting_1397164(226403, -), ADediting_1397183(226900, -), ADediting_1397184(226937, -), ADediting_1397185(226940, -), ADediting_1397186(226941, -), ADediting_1397187(226949, -), ADediting_1397188(226957, -), ADediting_1397189(226961, -), ADediting_1397190(226970, -), ADediting_1397191(226971, -), ADediting_1397192(226973, -), ADediting_1397193(226976, -), ADediting_1397194(226980, -), ADediting_1397195(226986, -), ADediting_1397196(226989, -), ADediting_1397197(226997, -), ADediting_1397198(227003, -), ADediting_1397199(227009, -), ADediting_1397200(227068, -), ADediting_1397201(227078, -), ADediting_1397202(227092, -), ADediting_1397203(227102, -), ADediting_1397204(227107, -), ADediting_1397205(227111, -), ADediting_1397206(227129, -), ADediting_1397207(227132, -), ADediting_1397208(227137, -), ADediting_1397209(227138, -), ADediting_1397210(227328, -), ADediting_1397211(227340, -), ADediting_1397212(227341, -), ADediting_1397213(227342, -), ADediting_1397214(227367, -), ADediting_1397215(227373, -), ADediting_1397216(227405, -), ADediting_1397217(227427, -), ADediting_1397218(227428, -), ADediting_1397219(227437, -), ADediting_1397220(227457, -), ADediting_1397221(227461, -), ADediting_1397222(227463, -), ADediting_1397223(227473, -), ADediting_1397224(227476, -), ADediting_1397225(227485, -), ADediting_1397226(227525, -), ADediting_1397227(227576, -), ADediting_1397230(228246, -), ADediting_1397231(228266, -), ADediting_1397232(228297, -), ADediting_1397233(228306, -), ADediting_1397234(228336, -), ADediting_1397235(228340, -), ADediting_1397236(228342, -), ADediting_1397237(228381, -), ADediting_1397238(228425, -), ADediting_1397250(230095, -), ADediting_1397251(230112, -), ADediting_1397252(230120, -), ADediting_1397253(230121, -), ADediting_1397254(230145, -), ADediting_1397255(230255, -), ADediting_1397256(230258, -), ADediting_1397260(230331, -), ADediting_1397261(230339, -), ADediting_1397355(230710, -), ADediting_1397356(230821, -), ADediting_1590228(225989, -), ADediting_1590234(226323, -), ADediting_1590235(227498, -), ADediting_1590236(228401, -), ADediting_1590237(230272, -), ADediting_1669180(227029, -), ADediting_1669181(227034, -), ADediting_1669182(227038, -),

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RNA editing positional annotations for RPL23AP53 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_1397032chr8_225703_-ncRNA_intronic
ADediting_1397053chr8_225831_-ncRNA_intronic
ADediting_1397054chr8_225832_-ncRNA_intronic
ADediting_1397058chr8_225854_-ncRNA_intronic
ADediting_1397059chr8_225901_-ncRNA_intronic
ADediting_1397084chr8_225934_-ncRNA_intronic
ADediting_1397102chr8_226029_-ncRNA_intronic
ADediting_1397103chr8_226035_-ncRNA_intronic
ADediting_1397104chr8_226049_-ncRNA_intronic
ADediting_1397105chr8_226089_-ncRNA_intronic
ADediting_1397116chr8_226096_-ncRNA_intronic
ADediting_1397117chr8_226097_-ncRNA_intronic
ADediting_1397118chr8_226101_-ncRNA_intronic
ADediting_1397126chr8_226162_-ncRNA_intronic
ADediting_1397127chr8_226163_-ncRNA_intronic
ADediting_1397129chr8_226169_-ncRNA_intronic
ADediting_1397133chr8_226182_-ncRNA_intronic
ADediting_1397134chr8_226183_-ncRNA_intronic
ADediting_1397135chr8_226214_-ncRNA_intronic
ADediting_1397136chr8_226288_-ncRNA_intronic
ADediting_1397137chr8_226310_-ncRNA_intronic
ADediting_1397145chr8_226324_-ncRNA_intronic
ADediting_1397146chr8_226328_-ncRNA_intronic
ADediting_1397161chr8_226334_-ncRNA_intronic
ADediting_1397162chr8_226347_-ncRNA_intronic
ADediting_1397163chr8_226402_-ncRNA_intronic
ADediting_1397164chr8_226403_-ncRNA_intronic
ADediting_1397183chr8_226900_-ncRNA_intronic
ADediting_1397184chr8_226937_-ncRNA_intronic
ADediting_1397185chr8_226940_-ncRNA_intronic
ADediting_1397186chr8_226941_-ncRNA_intronic
ADediting_1397187chr8_226949_-ncRNA_intronic
ADediting_1397188chr8_226957_-ncRNA_intronic
ADediting_1397189chr8_226961_-ncRNA_intronic
ADediting_1397190chr8_226970_-ncRNA_intronic
ADediting_1397191chr8_226971_-ncRNA_intronic
ADediting_1397192chr8_226973_-ncRNA_intronic
ADediting_1397193chr8_226976_-ncRNA_intronic
ADediting_1397194chr8_226980_-ncRNA_intronic
ADediting_1397195chr8_226986_-ncRNA_intronic
ADediting_1397196chr8_226989_-ncRNA_intronic
ADediting_1397197chr8_226997_-ncRNA_intronic
ADediting_1397198chr8_227003_-ncRNA_intronic
ADediting_1397199chr8_227009_-ncRNA_intronic
ADediting_1397200chr8_227068_-ncRNA_intronic
ADediting_1397201chr8_227078_-ncRNA_intronic
ADediting_1397202chr8_227092_-ncRNA_intronic
ADediting_1397203chr8_227102_-ncRNA_intronic
ADediting_1397204chr8_227107_-ncRNA_intronic
ADediting_1397205chr8_227111_-ncRNA_intronic
ADediting_1397206chr8_227129_-ncRNA_intronic
ADediting_1397207chr8_227132_-ncRNA_intronic
ADediting_1397208chr8_227137_-ncRNA_intronic
ADediting_1397209chr8_227138_-ncRNA_intronic
ADediting_1397210chr8_227328_-ncRNA_intronic
ADediting_1397211chr8_227340_-ncRNA_intronic
ADediting_1397212chr8_227341_-ncRNA_intronic
ADediting_1397213chr8_227342_-ncRNA_intronic
ADediting_1397214chr8_227367_-ncRNA_intronic
ADediting_1397215chr8_227373_-ncRNA_intronic
ADediting_1397216chr8_227405_-ncRNA_intronic
ADediting_1397217chr8_227427_-ncRNA_intronic
ADediting_1397218chr8_227428_-ncRNA_intronic
ADediting_1397219chr8_227437_-ncRNA_intronic
ADediting_1397220chr8_227457_-ncRNA_intronic
ADediting_1397221chr8_227461_-ncRNA_intronic
ADediting_1397222chr8_227463_-ncRNA_intronic
ADediting_1397223chr8_227473_-ncRNA_intronic
ADediting_1397224chr8_227476_-ncRNA_intronic
ADediting_1397225chr8_227485_-ncRNA_intronic
ADediting_1397226chr8_227525_-ncRNA_intronic
ADediting_1397227chr8_227576_-ncRNA_intronic
ADediting_1397230chr8_228246_-ncRNA_intronic
ADediting_1397231chr8_228266_-ncRNA_intronic
ADediting_1397232chr8_228297_-ncRNA_intronic
ADediting_1397233chr8_228306_-ncRNA_intronic
ADediting_1397234chr8_228336_-ncRNA_intronic
ADediting_1397235chr8_228340_-ncRNA_intronic
ADediting_1397236chr8_228342_-ncRNA_intronic
ADediting_1397237chr8_228381_-ncRNA_intronic
ADediting_1397238chr8_228425_-ncRNA_intronic
ADediting_1397250chr8_230095_-ncRNA_exonic
ADediting_1397251chr8_230112_-ncRNA_exonic
ADediting_1397252chr8_230120_-ncRNA_exonic
ADediting_1397253chr8_230121_-ncRNA_exonic
ADediting_1397254chr8_230145_-ncRNA_exonic
ADediting_1397255chr8_230255_-ncRNA_intronic
ADediting_1397256chr8_230258_-ncRNA_intronic
ADediting_1397260chr8_230331_-ncRNA_intronic
ADediting_1397261chr8_230339_-ncRNA_intronic
ADediting_1397355chr8_230710_-ncRNA_intronic
ADediting_1397356chr8_230821_-ncRNA_exonic
ADediting_1590228chr8_225989_-ncRNA_intronic
ADediting_1590234chr8_226323_-ncRNA_intronic
ADediting_1590235chr8_227498_-ncRNA_intronic
ADediting_1590236chr8_228401_-ncRNA_intronic
ADediting_1590237chr8_230272_-ncRNA_intronic
ADediting_1669180chr8_227029_-ncRNA_intronic
ADediting_1669181chr8_227034_-ncRNA_intronic
ADediting_1669182chr8_227038_-ncRNA_intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_1397032chr8_225703_-SINEAluName=AluSz6
ADediting_1397053chr8_225831_-SINEAluName=AluSz6
ADediting_1397054chr8_225832_-SINEAluName=AluSz6
ADediting_1397058chr8_225854_-SINEAluName=AluSz6
ADediting_1397059chr8_225901_-SINEAluName=AluSz6
ADediting_1397084chr8_225934_-SINEAluName=AluSz6
ADediting_1397102chr8_226029_-SINEAluName=AluSp
ADediting_1397103chr8_226035_-SINEAluName=AluSp
ADediting_1397104chr8_226049_-SINEAluName=AluSp
ADediting_1397105chr8_226089_-SINEAluName=AluSp
ADediting_1397116chr8_226096_-SINEAluName=AluSp
ADediting_1397117chr8_226097_-SINEAluName=AluSp
ADediting_1397118chr8_226101_-SINEAluName=AluSp
ADediting_1397126chr8_226162_-SINEAluName=AluSp
ADediting_1397127chr8_226163_-SINEAluName=AluSp
ADediting_1397129chr8_226169_-SINEAluName=AluSp
ADediting_1397133chr8_226182_-SINEAluName=AluSp
ADediting_1397134chr8_226183_-SINEAluName=AluSp
ADediting_1397135chr8_226214_-SINEAluName=AluSp
ADediting_1397136chr8_226288_-SINEAluName=AluSx
ADediting_1397137chr8_226310_-SINEAluName=AluSx
ADediting_1397145chr8_226324_-SINEAluName=AluSx
ADediting_1397146chr8_226328_-SINEAluName=AluSx
ADediting_1397161chr8_226334_-SINEAluName=AluSx
ADediting_1397162chr8_226347_-SINEAluName=AluSx
ADediting_1397163chr8_226402_-SINEAluName=AluSx
ADediting_1397164chr8_226403_-SINEAluName=AluSx
ADediting_1397183chr8_226900_-SINEAluName=AluSx
ADediting_1397184chr8_226937_-SINEAluName=AluSx
ADediting_1397185chr8_226940_-SINEAluName=AluSx
ADediting_1397186chr8_226941_-SINEAluName=AluSx
ADediting_1397187chr8_226949_-SINEAluName=AluSx
ADediting_1397188chr8_226957_-SINEAluName=AluSx
ADediting_1397189chr8_226961_-SINEAluName=AluSx
ADediting_1397190chr8_226970_-SINEAluName=AluSx
ADediting_1397191chr8_226971_-SINEAluName=AluSx
ADediting_1397192chr8_226973_-SINEAluName=AluSx
ADediting_1397193chr8_226976_-SINEAluName=AluSx
ADediting_1397194chr8_226980_-SINEAluName=AluSx
ADediting_1397195chr8_226986_-SINEAluName=AluSx
ADediting_1397196chr8_226989_-SINEAluName=AluSx
ADediting_1397197chr8_226997_-SINEAluName=AluSx
ADediting_1397198chr8_227003_-SINEAluName=AluSx
ADediting_1397199chr8_227009_-SINEAluName=AluSx
ADediting_1397200chr8_227068_-SINEAluName=AluSx
ADediting_1397201chr8_227078_-SINEAluName=AluSx
ADediting_1397202chr8_227092_-SINEAluName=AluSx
ADediting_1397203chr8_227102_-SINEAluName=AluSx
ADediting_1397204chr8_227107_-SINEAluName=AluSx
ADediting_1397205chr8_227111_-SINEAluName=AluSx
ADediting_1397206chr8_227129_-SINEAluName=AluSx
ADediting_1397207chr8_227132_-SINEAluName=AluSx
ADediting_1397208chr8_227137_-SINEAluName=AluSx
ADediting_1397209chr8_227138_-SINEAluName=AluSx
ADediting_1397210chr8_227328_-SINEAluName=AluSx1
ADediting_1397211chr8_227340_-SINEAluName=AluSx1
ADediting_1397212chr8_227341_-SINEAluName=AluSx1
ADediting_1397213chr8_227342_-SINEAluName=AluSx1
ADediting_1397214chr8_227367_-SINEAluName=AluSx1
ADediting_1397215chr8_227373_-SINEAluName=AluSx1
ADediting_1397216chr8_227405_-SINEAluName=AluSx1
ADediting_1397217chr8_227427_-SINEAluName=AluSx1
ADediting_1397218chr8_227428_-SINEAluName=AluSx1
ADediting_1397219chr8_227437_-SINEAluName=AluSx1
ADediting_1397220chr8_227457_-SINEAluName=AluSx1
ADediting_1397221chr8_227461_-SINEAluName=AluSx1
ADediting_1397222chr8_227463_-SINEAluName=AluSx1
ADediting_1397223chr8_227473_-SINEAluName=AluSx1
ADediting_1397224chr8_227476_-SINEAluName=AluSx1
ADediting_1397225chr8_227485_-SINEAluName=AluSx1
ADediting_1397226chr8_227525_-SINEAluName=AluSx1
ADediting_1397227chr8_227576_-SINEAluName=AluSx1
ADediting_1397230chr8_228246_-SINEAluName=AluSx1
ADediting_1397231chr8_228266_-SINEAluName=AluSx1
ADediting_1397232chr8_228297_-SINEAluName=AluSx1
ADediting_1397233chr8_228306_-SINEAluName=AluSx1
ADediting_1397234chr8_228336_-SINEAluName=AluSx1
ADediting_1397235chr8_228340_-SINEAluName=AluSx1
ADediting_1397236chr8_228342_-SINEAluName=AluSx1
ADediting_1397237chr8_228381_-SINEAluName=AluSx1
ADediting_1397238chr8_228425_-SINEAluName=AluSx1
ADediting_1397250chr8_230095_-SINEAluName=AluJr
ADediting_1397251chr8_230112_-SINEAluName=AluJr
ADediting_1397252chr8_230120_-SINEAluName=AluJr
ADediting_1397253chr8_230121_-SINEAluName=AluJr
ADediting_1397254chr8_230145_-SINEAluName=AluJr
ADediting_1397255chr8_230255_-SINEAluName=AluJr
ADediting_1397256chr8_230258_-SINEAluName=AluJr
ADediting_1397260chr8_230331_-SINEAluName=AluJr
ADediting_1397261chr8_230339_-SINEAluName=AluJr
ADediting_1397355chr8_230710_-SINEAluName=AluSq2
ADediting_1397356chr8_230821_-SINEAluName=AluSq2
ADediting_1590228chr8_225989_-SINEAluName=AluSp
ADediting_1590234chr8_226323_-SINEAluName=AluSx
ADediting_1590235chr8_227498_-SINEAluName=AluSx1
ADediting_1590236chr8_228401_-SINEAluName=AluSx1
ADediting_1590237chr8_230272_-SINEAluName=AluJr
ADediting_1669180chr8_227029_-SINEAluName=AluSx
ADediting_1669181chr8_227034_-SINEAluName=AluSx
ADediting_1669182chr8_227038_-SINEAluName=AluSx

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RNA A-to-I editing events in the alternative splicing sites for RPL23AP53

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for RPL23AP53

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for RPL23AP53

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for RPL23AP53

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1397250chr8_230095_-ENSG00000223508.5ENST00000606507.1RPL23AP53-202hsa-miR-6125chr82300942301018mer-1a230094230114159-28.07
ADediting_1397251chr8_230112_-ENSG00000223508.5ENST00000606507.1RPL23AP53-202hsa-miR-4767chr82301072301137mer-m8230106230130141-19.29
ADediting_1397252chr8_230120_-ENSG00000223508.5ENST00000606507.1RPL23AP53-202hsa-miR-3622a-3pchr82301162301238mer-1a230116230137144-13.77
ADediting_1397252chr8_230120_-ENSG00000223508.5ENST00000606507.1RPL23AP53-202hsa-miR-3622b-3pchr82301162301238mer-1a230116230136153-19.33
ADediting_1397252chr8_230120_-ENSG00000223508.5ENST00000606507.1RPL23AP53-202hsa-miR-4324chr82301192301257mer-m8230118230137142-10.95
ADediting_1397254chr8_230145_-ENSG00000223508.5ENST00000606507.1RPL23AP53-202hsa-miR-3187-5pchr82301452301517mer-m8230144230166141-24
ADediting_1397254chr8_230145_-ENSG00000223508.5ENST00000606507.1RPL23AP53-202hsa-miR-5189-5pchr82301452301517mer-m8230144230169147-21.63
ADediting_1397254chr8_230145_-ENSG00000223508.5ENST00000606507.1RPL23AP53-202hsa-miR-612chr82301452301517mer-m8230144230166148-23.29
ADediting_1397254chr8_230145_-ENSG00000223508.5ENST00000606507.1RPL23AP53-202hsa-miR-661chr82301432301497mer-m8230142230165148-20.45
ADediting_1397254chr8_230145_-ENSG00000223508.5ENST00000606507.1RPL23AP53-202hsa-miR-6849-3pchr82301402301467mer-m8230139230160148-17.9
ADediting_1397254chr8_230145_-ENSG00000223508.5ENST00000606507.1RPL23AP53-202hsa-miR-6860chr82301452301517mer-m8230144230165142-18.93
ADediting_1397254chr8_230145_-ENSG00000223508.5ENST00000606507.1RPL23AP53-202hsa-miR-939-3pchr82301442301507mer-m8230143230163140-15.96
ADediting_1397356chr8_230821_-ENSG00000223508.5ENST00000606507.1RPL23AP53-202hsa-miR-6771-5pchr82308202308267mer-m8230819230838156-32.45

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1397251chr8_230112_-ENSG00000223508.5ENST00000606507.1RPL23AP53-202hsa-miR-3165chr82301102301167mer-m8230109230128149-17.11
ADediting_1397251chr8_230112_-ENSG00000223508.5ENST00000606507.1RPL23AP53-202hsa-miR-6745chr82301092301157mer-m8230108230132146-23.38
ADediting_1397254chr8_230145_-ENSG00000223508.5ENST00000606507.1RPL23AP53-202hsa-miR-4453chr82301422301487mer-m8230141230161153-17.62
ADediting_1397254chr8_230145_-ENSG00000223508.5ENST00000606507.1RPL23AP53-202hsa-miR-4538chr82301422301487mer-m8230141230161147-14.33
ADediting_1397254chr8_230145_-ENSG00000223508.5ENST00000606507.1RPL23AP53-202hsa-miR-635chr82301442301507mer-m8230143230164148-17.68
ADediting_1397356chr8_230821_-ENSG00000223508.5ENST00000606507.1RPL23AP53-202hsa-miR-12126chr82308172308248mer-1a230817230840147-16.86
ADediting_1397356chr8_230821_-ENSG00000223508.5ENST00000606507.1RPL23AP53-202hsa-miR-1273h-5pchr82308202308267mer-1a230820230840143-20.74
ADediting_1397356chr8_230821_-ENSG00000223508.5ENST00000606507.1RPL23AP53-202hsa-miR-30c-1-3pchr82308202308278mer-1a230820230841140-13.56
ADediting_1397356chr8_230821_-ENSG00000223508.5ENST00000606507.1RPL23AP53-202hsa-miR-30c-2-3pchr82308202308278mer-1a230820230844145-16.82
ADediting_1397356chr8_230821_-ENSG00000223508.5ENST00000606507.1RPL23AP53-202hsa-miR-6788-5pchr82308202308278mer-1a230820230843149-20.15
ADediting_1397356chr8_230821_-ENSG00000223508.5ENST00000606507.1RPL23AP53-202hsa-miR-887-5pchr82308202308267mer-m8230819230838143-20.14

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for RPL23AP53

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000606507.1lncRNASoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_1397250ENST00000606507.1chr8_230095_-283-98.30-98.60-103.50
ADediting_1397251ENST00000606507.1chr8_230112_-266-98.80-98.60-103.50
ADediting_1397252ENST00000606507.1chr8_230120_-258-99.90-98.60-103.50
ADediting_1397253ENST00000606507.1chr8_230121_-257-98.60-98.60-103.50
ADediting_1397254ENST00000606507.1chr8_230145_-233-102.70-98.60-103.50
ADediting_1397356ENST00000606507.1chr8_230821_-190-99.10-98.60-103.50

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Relation with ADAR for RPL23AP53

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
CERADediting_1397059chr8_225901_-0.001348696799422870.2593959582551243.47927760490725e-050.3311781354038850.7074186002001670.0308963208229086
CERADediting_1397102chr8_226029_-9.07910729423048e-060.3535472372184371.7077524781104e-070.4113079188910150.1584692852858220.115726336754087
CERADediting_1397103chr8_226035_-3.30782570233754e-050.3320514481387492.56094986060987e-050.3364340158170740.1489466842481630.118417417025688
CERADediting_1397104chr8_226049_-0.0009882995831029360.2662951768920570.0001302520265016510.3073646894812690.08505976952895540.141081169867146
CERADediting_1397105chr8_226089_-0.002512160455380380.2450124642951985.49207916555459e-050.3231667172846280.5452711467838180.0497724655403072
CERADediting_1397118chr8_226101_-2.5657927430163e-050.3364019035552692.21590223721182e-070.4078398579491550.1855640136272020.108677860314471
CERADediting_1397126chr8_226162_-0.002014298060311740.2502134537858521.09922326949762e-070.4170861075727780.2078705580030370.103422227354947
DLPFCADediting_1397129chr8_226169_-0.06113216139996680.1064806420840170.9953222951101840.0003343277198323711.6352980247595e-080.313841338134611
CERADediting_1397129chr8_226169_-0.0001227589663153690.3084775984397465.51636892839023e-080.4259165338341840.6826289757348530.0336568668584572
CERADediting_1397135chr8_226214_-0.0002003739448783030.2991379029952889.97461605285227e-070.3870024113460480.7073283249774910.0309063097560359
CERADediting_1397161chr8_226334_-0.003015131180647850.2406324473239480.0001299838192136750.3074034821800430.3997633983762870.0692493116750333
DLPFCADediting_1397188chr8_226957_-0.759424469100984-0.01746229005985390.0521204419980626-0.1104145630394193.24453806689376e-110.365222064843681
DLPFCADediting_1397189chr8_226961_-0.8601737010838990.01004514874557230.0306856039181738-0.1227749668789589.54232127448991e-210.497030933257403
DLPFCADediting_1397190chr8_226970_-0.9919686880743230.0005740251004186860.0188517691732057-0.1333255486157141.59543997239882e-170.458547499587706
DLPFCADediting_1397193chr8_226976_-0.468694636479134-0.04130406807098250.0215860656821179-0.1304622565068772.56060959915573e-110.367004264320752
DLPFCADediting_1397194chr8_226980_-0.535651854295713-0.03531132066080790.0149224742014142-0.138150926706687.69460289608258e-120.375890636024756
DLPFCADediting_1397196chr8_226989_-0.535627627510956-0.03531341642115850.00893015593148245-0.148283090458439.75542036345241e-140.406084175647183
DLPFCADediting_1397205chr8_227111_-0.300083365256055-0.059042466957420.00435469874564753-0.1615282030544621.87631819094446e-100.351654288601382
DLPFCADediting_1397213chr8_227342_-0.215837063513527-0.07049243892730590.0124375311883435-0.1418156962262122.47959749308577e-090.330438670210377
DLPFCADediting_1397214chr8_227367_-0.408663971958973-0.04709187699972190.0290249840045812-0.124016369323272.42571752235047e-080.310240239275996
DLPFCADediting_1397220chr8_227457_-0.796416229991648-0.01471136659625290.033782211639531-0.1206059013425591.90195375003729e-200.493652217189082
DLPFCADediting_1397222chr8_227463_-0.450765710269875-0.04298607290870470.0441680930647006-0.1143885293806291.43512976454564e-120.387866631388153

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC1.61034048318445e-100.3528620348892792.1768150134077e-060.2652404158536920.002584299298898150.170576600691875
CER8.48027205272e-300.7626362030704652.97302494990694e-220.686756955651430.0237287051515760.184604502170003
TCX2.25948939291024e-160.6054633926039353.43000341621768e-050.3314249014115120.0006067419282092690.276768892710732
FP5.67751716702148e-120.486658380715091.06811823779293e-180.5987729363672890.7153261506161790.0275250860573437
IFG0.01489352128873690.4811478338410920.0987113744200780.3377319182396140.782198061469499-0.0582251759592952
PG1.01664117839598e-110.4721997366165472.54699581201376e-130.5029948126468390.8721290361648910.0118814552321586
STG0.0003686689396619010.3796308508900710.0003962086709824410.3777624544807080.8692911956704370.0182264602479606

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Relation with AD stages for RPL23AP53

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
CER9.20533063673437e-050.367332069109917
TCX0.0009501444689394780.316459722671589

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RelatedDrugs for RPL23AP53

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for RPL23AP53

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource