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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

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Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for SEPTIN7P2

check button Gene summary
Gene informationGene symbol

SEPTIN7P2

Gene ID

641977

Gene nameseptin 7 pseudogene 2
SynonymsSEPT13|SEPT7B|SEPT7P2
Cytomap

7p12.3

Type of genepseudo
Descriptionseptin 13septin 7B
Modification date20200313
UniProtAcc

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for SEPTIN7P2

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_1334331(45725170, -), ADediting_1334332(45725233, -), ADediting_1334333(45725239, -), ADediting_1334334(45725248, -), ADediting_1334335(45725258, -), ADediting_1334336(45725306, -), ADediting_1334337(45725323, -), ADediting_1334338(45729041, -), ADediting_1334339(45729055, -), ADediting_1334340(45729123, -), ADediting_1334341(45729161, -), ADediting_1334342(45736470, -), ADediting_1334343(45736505, -), ADediting_1334344(45736506, -), ADediting_1334345(45736514, -), ADediting_1334346(45740131, -), ADediting_1334347(45740132, -), ADediting_1334348(45740136, -), ADediting_1334349(45740156, -), ADediting_1334350(45740161, -), ADediting_1334351(45740187, -), ADediting_1334352(45740191, -), ADediting_1334353(45740201, -), ADediting_1334354(45740213, -), ADediting_1334355(45740223, -), ADediting_1334356(45740236, -), ADediting_1334357(45740242, -), ADediting_1334358(45740266, -), ADediting_1334359(45740289, -), ADediting_1334360(45740333, -), ADediting_1334361(45740334, -), ADediting_1334362(45741039, -), ADediting_1334363(45741093, -), ADediting_1334364(45741131, -), ADediting_1334365(45741134, -), ADediting_1334366(45741175, -), ADediting_1334367(45741180, -), ADediting_1334368(45741185, -), ADediting_1334369(45741188, -), ADediting_1334370(45741189, -), ADediting_1334371(45741197, -), ADediting_1334372(45741214, -), ADediting_1334373(45741228, -), ADediting_1334374(45741234, -), ADediting_1334375(45741240, -), ADediting_1334376(45741258, -), ADediting_1334377(45742071, -), ADediting_1334378(45742089, -), ADediting_1334379(45742102, -), ADediting_1334380(45742128, -), ADediting_1334381(45742141, -), ADediting_1334382(45742145, -), ADediting_1334383(45742149, -), ADediting_1334384(45742155, -), ADediting_1334385(45742168, -), ADediting_1334386(45742194, -), ADediting_1334387(45742195, -), ADediting_1334388(45742198, -), ADediting_1334389(45742223, -), ADediting_1334390(45742234, -), ADediting_1334391(45742235, -), ADediting_1334392(45742295, -), ADediting_1334393(45743284, -), ADediting_1334394(45743295, -), ADediting_1334395(45743375, -), ADediting_1334396(45743377, -), ADediting_1334397(45743387, -), ADediting_1334398(45743400, -), ADediting_1334399(45743404, -), ADediting_1334400(45743443, -), ADediting_1334401(45743449, -), ADediting_1334402(45767880, -), ADediting_1587648(45725298, -), ADediting_1587649(45729025, -), ADediting_1587650(45733646, -), ADediting_1666145(45730384, -), ADediting_1666146(45733611, -), ADediting_1666147(45733629, -), ADediting_1666148(45733636, -), ADediting_1666149(45733652, -),

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RNA editing positional annotations for SEPTIN7P2 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_1334331chr7_45725170_-ncRNA_exonic
ADediting_1334332chr7_45725233_-ncRNA_exonic
ADediting_1334333chr7_45725239_-ncRNA_exonic
ADediting_1334334chr7_45725248_-ncRNA_exonic
ADediting_1334335chr7_45725258_-ncRNA_exonic
ADediting_1334336chr7_45725306_-ncRNA_exonic
ADediting_1334337chr7_45725323_-ncRNA_exonic
ADediting_1334338chr7_45729041_-ncRNA_intronic
ADediting_1334339chr7_45729055_-ncRNA_intronic
ADediting_1334340chr7_45729123_-ncRNA_intronic
ADediting_1334341chr7_45729161_-ncRNA_intronic
ADediting_1334342chr7_45736470_-ncRNA_intronic
ADediting_1334343chr7_45736505_-ncRNA_intronic
ADediting_1334344chr7_45736506_-ncRNA_intronic
ADediting_1334345chr7_45736514_-ncRNA_intronic
ADediting_1334346chr7_45740131_-ncRNA_intronic
ADediting_1334347chr7_45740132_-ncRNA_intronic
ADediting_1334348chr7_45740136_-ncRNA_intronic
ADediting_1334349chr7_45740156_-ncRNA_intronic
ADediting_1334350chr7_45740161_-ncRNA_intronic
ADediting_1334351chr7_45740187_-ncRNA_intronic
ADediting_1334352chr7_45740191_-ncRNA_intronic
ADediting_1334353chr7_45740201_-ncRNA_intronic
ADediting_1334354chr7_45740213_-ncRNA_intronic
ADediting_1334355chr7_45740223_-ncRNA_intronic
ADediting_1334356chr7_45740236_-ncRNA_intronic
ADediting_1334357chr7_45740242_-ncRNA_intronic
ADediting_1334358chr7_45740266_-ncRNA_intronic
ADediting_1334359chr7_45740289_-ncRNA_intronic
ADediting_1334360chr7_45740333_-ncRNA_intronic
ADediting_1334361chr7_45740334_-ncRNA_intronic
ADediting_1334362chr7_45741039_-ncRNA_intronic
ADediting_1334363chr7_45741093_-ncRNA_intronic
ADediting_1334364chr7_45741131_-ncRNA_intronic
ADediting_1334365chr7_45741134_-ncRNA_intronic
ADediting_1334366chr7_45741175_-ncRNA_intronic
ADediting_1334367chr7_45741180_-ncRNA_intronic
ADediting_1334368chr7_45741185_-ncRNA_intronic
ADediting_1334369chr7_45741188_-ncRNA_intronic
ADediting_1334370chr7_45741189_-ncRNA_intronic
ADediting_1334371chr7_45741197_-ncRNA_intronic
ADediting_1334372chr7_45741214_-ncRNA_intronic
ADediting_1334373chr7_45741228_-ncRNA_intronic
ADediting_1334374chr7_45741234_-ncRNA_intronic
ADediting_1334375chr7_45741240_-ncRNA_intronic
ADediting_1334376chr7_45741258_-ncRNA_intronic
ADediting_1334377chr7_45742071_-ncRNA_intronic
ADediting_1334378chr7_45742089_-ncRNA_intronic
ADediting_1334379chr7_45742102_-ncRNA_intronic
ADediting_1334380chr7_45742128_-ncRNA_intronic
ADediting_1334381chr7_45742141_-ncRNA_intronic
ADediting_1334382chr7_45742145_-ncRNA_intronic
ADediting_1334383chr7_45742149_-ncRNA_intronic
ADediting_1334384chr7_45742155_-ncRNA_intronic
ADediting_1334385chr7_45742168_-ncRNA_intronic
ADediting_1334386chr7_45742194_-ncRNA_intronic
ADediting_1334387chr7_45742195_-ncRNA_intronic
ADediting_1334388chr7_45742198_-ncRNA_intronic
ADediting_1334389chr7_45742223_-ncRNA_intronic
ADediting_1334390chr7_45742234_-ncRNA_intronic
ADediting_1334391chr7_45742235_-ncRNA_intronic
ADediting_1334392chr7_45742295_-ncRNA_intronic
ADediting_1334393chr7_45743284_-ncRNA_intronic
ADediting_1334394chr7_45743295_-ncRNA_intronic
ADediting_1334395chr7_45743375_-ncRNA_intronic
ADediting_1334396chr7_45743377_-ncRNA_intronic
ADediting_1334397chr7_45743387_-ncRNA_intronic
ADediting_1334398chr7_45743400_-ncRNA_intronic
ADediting_1334399chr7_45743404_-ncRNA_intronic
ADediting_1334400chr7_45743443_-ncRNA_intronic
ADediting_1334401chr7_45743449_-ncRNA_intronic
ADediting_1334402chr7_45767880_-ncRNA_intronic
ADediting_1587648chr7_45725298_-ncRNA_exonic
ADediting_1587649chr7_45729025_-ncRNA_exonic
ADediting_1587650chr7_45733646_-ncRNA_intronic
ADediting_1666145chr7_45730384_-ncRNA_intronic
ADediting_1666146chr7_45733611_-ncRNA_intronic
ADediting_1666147chr7_45733629_-ncRNA_intronic
ADediting_1666148chr7_45733636_-ncRNA_intronic
ADediting_1666149chr7_45733652_-ncRNA_intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_1334331chr7_45725170_-SINEAluName=AluSx
ADediting_1334332chr7_45725233_-SINEAluName=AluSx
ADediting_1334333chr7_45725239_-SINEAluName=AluSx
ADediting_1334334chr7_45725248_-SINEAluName=AluSx
ADediting_1334335chr7_45725258_-SINEAluName=AluSx
ADediting_1334336chr7_45725306_-SINEAluName=AluSx
ADediting_1334337chr7_45725323_-SINEAluName=AluSx
ADediting_1334338chr7_45729041_-SINEAluName=AluY
ADediting_1334339chr7_45729055_-SINEAluName=AluY
ADediting_1334340chr7_45729123_-SINEAluName=AluY
ADediting_1334341chr7_45729161_-SINEAluName=AluY
ADediting_1334342chr7_45736470_-SINEAluName=AluYa5
ADediting_1334343chr7_45736505_-SINEAluName=AluYa5
ADediting_1334344chr7_45736506_-SINEAluName=AluYa5
ADediting_1334345chr7_45736514_-SINEAluName=AluYa5
ADediting_1334346chr7_45740131_-SINEAluName=AluSc
ADediting_1334347chr7_45740132_-SINEAluName=AluSc
ADediting_1334348chr7_45740136_-SINEAluName=AluSc
ADediting_1334349chr7_45740156_-SINEAluName=AluSc
ADediting_1334350chr7_45740161_-SINEAluName=AluSc
ADediting_1334351chr7_45740187_-SINEAluName=AluSc
ADediting_1334352chr7_45740191_-SINEAluName=AluSc
ADediting_1334353chr7_45740201_-SINEAluName=AluSc
ADediting_1334354chr7_45740213_-SINEAluName=AluSc
ADediting_1334355chr7_45740223_-SINEAluName=AluSc
ADediting_1334356chr7_45740236_-SINEAluName=AluSc
ADediting_1334357chr7_45740242_-SINEAluName=AluSc
ADediting_1334358chr7_45740266_-SINEAluName=AluSc
ADediting_1334359chr7_45740289_-SINEAluName=AluSc
ADediting_1334360chr7_45740333_-SINEAluName=AluSc
ADediting_1334361chr7_45740334_-SINEAluName=AluSc
ADediting_1334362chr7_45741039_-SINEAluName=AluSx1
ADediting_1334363chr7_45741093_-SINEAluName=AluSx1
ADediting_1334364chr7_45741131_-SINEAluName=AluSx1
ADediting_1334365chr7_45741134_-SINEAluName=AluSx1
ADediting_1334366chr7_45741175_-SINEAluName=AluSx1
ADediting_1334367chr7_45741180_-SINEAluName=AluSx1
ADediting_1334368chr7_45741185_-SINEAluName=AluSx1
ADediting_1334369chr7_45741188_-SINEAluName=AluSx1
ADediting_1334370chr7_45741189_-SINEAluName=AluSx1
ADediting_1334371chr7_45741197_-SINEAluName=AluSx1
ADediting_1334372chr7_45741214_-SINEAluName=AluSx1
ADediting_1334373chr7_45741228_-SINEAluName=AluSx1
ADediting_1334374chr7_45741234_-SINEAluName=AluSx1
ADediting_1334375chr7_45741240_-SINEAluName=AluSx1
ADediting_1334376chr7_45741258_-SINEAluName=AluSx1
ADediting_1334377chr7_45742071_-SINEAluName=AluJb
ADediting_1334378chr7_45742089_-SINEAluName=AluJb
ADediting_1334379chr7_45742102_-SINEAluName=AluJb
ADediting_1334380chr7_45742128_-SINEAluName=AluJb
ADediting_1334381chr7_45742141_-SINEAluName=AluJb
ADediting_1334382chr7_45742145_-SINEAluName=AluJb
ADediting_1334383chr7_45742149_-SINEAluName=AluJb
ADediting_1334384chr7_45742155_-SINEAluName=AluJb
ADediting_1334385chr7_45742168_-SINEAluName=AluJb
ADediting_1334386chr7_45742194_-SINEAluName=AluJb
ADediting_1334387chr7_45742195_-SINEAluName=AluJb
ADediting_1334388chr7_45742198_-SINEAluName=AluJb
ADediting_1334389chr7_45742223_-SINEAluName=AluJb
ADediting_1334390chr7_45742234_-SINEAluName=AluJb
ADediting_1334391chr7_45742235_-SINEAluName=AluJb
ADediting_1334392chr7_45742295_-SINEAluName=AluJb
ADediting_1334393chr7_45743284_-SINEAluName=AluSz
ADediting_1334394chr7_45743295_-SINEAluName=AluSz
ADediting_1334395chr7_45743375_-SINEAluName=AluSz
ADediting_1334396chr7_45743377_-SINEAluName=AluSz
ADediting_1334397chr7_45743387_-SINEAluName=AluSz
ADediting_1334398chr7_45743400_-SINEAluName=AluSz
ADediting_1334399chr7_45743404_-SINEAluName=AluSz
ADediting_1334400chr7_45743443_-SINEAluName=AluSz
ADediting_1334401chr7_45743449_-SINEAluName=AluSz
ADediting_1334402chr7_45767880_-SINEAluName=AluJb
ADediting_1587648chr7_45725298_-SINEAluName=AluSx
ADediting_1587649chr7_45729025_-SINEAluName=AluY
ADediting_1587650chr7_45733646_-DNATcMar-TiggerName=Tigger3c
ADediting_1666145chr7_45730384_-SINEAluName=AluY
ADediting_1666146chr7_45733611_-DNATcMar-TiggerName=Tigger3c
ADediting_1666147chr7_45733629_-DNATcMar-TiggerName=Tigger3c
ADediting_1666148chr7_45733636_-DNATcMar-TiggerName=Tigger3c
ADediting_1666149chr7_45733652_-DNATcMar-TiggerName=Tigger3c

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RNA A-to-I editing events in the alternative splicing sites for SEPTIN7P2

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
A3SSADediting_1334338chr7_45729041_-45729021:457290433ss18iGTATTTTTTTTTTTCAGTAGAGA5.22GTGTTTTTTTTTTTCAGTAGAGA6.24
A3SSADediting_1587649chr7_45729025_-45729021:457290433ss2iGTATTTTTTTTTTTCAGTAGAGA5.22GTATTTTTTTTTTTCAGTGGAGA-2.74
ESADediting_1334338chr7_45729041_-45729021:457290433ss18iGTATTTTTTTTTTTCAGTAGAGA5.22GTGTTTTTTTTTTTCAGTAGAGA6.24
ESADediting_1587649chr7_45729025_-45729021:457290433ss2iGTATTTTTTTTTTTCAGTAGAGA5.22GTATTTTTTTTTTTCAGTGGAGA-2.74
ESADediting_1587649chr7_45729025_-45729024:457290463ss2eTTTGTATTTTTTTTTTTCAGTAG7.92TTTGTATTTTTTTTTTTCAGTGG9.31
ESADediting_1334340chr7_45729123_-45729116:457291245ss2eCAGGTTCAT3.89CGGGTTCAT-2.75
ME2ADediting_1334338chr7_45729041_-45729024:457290463ss15iTTTGTATTTTTTTTTTTCAGTAG7.92TTTGTGTTTTTTTTTTTCAGTAG8.90

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SEPTIN7P2

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
boxplot
boxplot
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for SEPTIN7P2

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for SEPTIN7P2

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1334332chr7_45725233_-ENSG00000214765.8ENST00000429741.5SEPTIN7P2-207hsa-miR-340-3pchr745725232457252387mer-m84572523145725252149-16.57
ADediting_1334332chr7_45725233_-ENSG00000214765.8ENST00000429741.5SEPTIN7P2-207hsa-miR-6827-3pchr745725232457252387mer-m84572523145725251153-19.05
ADediting_1334335chr7_45725258_-ENSG00000214765.8ENST00000429741.5SEPTIN7P2-207hsa-miR-34a-3pchr745725255457252617mer-m84572525445725276145-11.29
ADediting_1334336chr7_45725306_-ENSG00000214765.8ENST00000429741.5SEPTIN7P2-207hsa-miR-6089chr745725301457253077mer-m84572530045725323158-33.19
ADediting_1334337chr7_45725323_-ENSG00000214765.8ENST00000429741.5SEPTIN7P2-207hsa-miR-3622a-3pchr745725319457253268mer-1a4572531945725340148-20.48
ADediting_1334337chr7_45725323_-ENSG00000214765.8ENST00000429741.5SEPTIN7P2-207hsa-miR-3622b-3pchr745725319457253268mer-1a4572531945725339153-21.99
ADediting_1587648chr7_45725298_-ENSG00000214765.8ENST00000429741.5SEPTIN7P2-207hsa-miR-514a-5pchr745725294457253018mer-1a4572529445725316159-20.61
ADediting_1587648chr7_45725298_-ENSG00000214765.8ENST00000429741.5SEPTIN7P2-207hsa-miR-516b-5pchr745725297457253037mer-m84572529645725316158-18.39
ADediting_1587648chr7_45725298_-ENSG00000214765.8ENST00000429741.5SEPTIN7P2-207hsa-miR-518c-5pchr745725296457253027mer-m84572529545725319161-21.06
ADediting_1587649chr7_45729025_-ENSG00000214765.8ENST00000428414.5SEPTIN7P2-205hsa-miR-136-5pchr745729021457367888mer-1a4572902145736803147-12.56

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1334331chr7_45725170_-ENSG00000214765.8ENST00000429741.5SEPTIN7P2-207hsa-miR-4478chr745725166457251727mer-m84572516545725181154-23.41
ADediting_1334331chr7_45725170_-ENSG00000214765.8ENST00000429741.5SEPTIN7P2-207hsa-miR-485-5pchr745725165457251717mer-m84572516445725185149-16.76
ADediting_1334331chr7_45725170_-ENSG00000214765.8ENST00000429741.5SEPTIN7P2-207hsa-miR-7160-5pchr745725168457251747mer-m84572516745725184148-19.34
ADediting_1334331chr7_45725170_-ENSG00000214765.8ENST00000429741.5SEPTIN7P2-207hsa-miR-7162-3pchr745725169457251757mer-m84572516845725186150-18.37
ADediting_1334332chr7_45725233_-ENSG00000214765.8ENST00000429741.5SEPTIN7P2-207hsa-miR-6760-3pchr745725230457252367mer-m84572522945725248145-14.09
ADediting_1334332chr7_45725233_-ENSG00000214765.8ENST00000429741.5SEPTIN7P2-207hsa-miR-6818-3pchr745725233457252397mer-m84572523245725253140-12.56
ADediting_1334333chr7_45725239_-ENSG00000214765.8ENST00000429741.5SEPTIN7P2-207hsa-miR-593-3pchr745725233457252397mer-1a4572523345725251140-19.02
ADediting_1334336chr7_45725306_-ENSG00000214765.8ENST00000429741.5SEPTIN7P2-207hsa-miR-4478chr745725302457253087mer-m84572530145725318146-20.42
ADediting_1334336chr7_45725306_-ENSG00000214765.8ENST00000429741.5SEPTIN7P2-207hsa-miR-4649-3pchr745725305457253117mer-m84572530445725324140-13.19
ADediting_1334336chr7_45725306_-ENSG00000214765.8ENST00000429741.5SEPTIN7P2-207hsa-miR-485-5pchr745725301457253077mer-m84572530045725321152-17.65
ADediting_1334336chr7_45725306_-ENSG00000214765.8ENST00000429741.5SEPTIN7P2-207hsa-miR-7160-5pchr745725304457253107mer-m84572530345725323141-15.44
ADediting_1334337chr7_45725323_-ENSG00000214765.8ENST00000429741.5SEPTIN7P2-207hsa-miR-3614-5pchr745725319457253257mer-1a4572531945725342140-17.8

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for SEPTIN7P2

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000429741.5lncRNASoverviewSoverview
ENST00000428414.5lncRNASoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_1334331ENST00000429741.5chr7_45725170_-1952-894.70-895.40-900.80
ADediting_1334332ENST00000429741.5chr7_45725233_-1889-895.80-895.40-900.80
ADediting_1334333ENST00000429741.5chr7_45725239_-1883-896.00-895.40-900.80
ADediting_1334334ENST00000429741.5chr7_45725248_-1874-896.30-895.40-900.80
ADediting_1334335ENST00000429741.5chr7_45725258_-1864-895.10-895.40-900.80
ADediting_1587648ENST00000429741.5chr7_45725298_-1824-897.30-895.40-900.80
ADediting_1334336ENST00000429741.5chr7_45725306_-1816-895.80-895.40-900.80
ADediting_1334337ENST00000429741.5chr7_45725323_-1799-897.60-895.40-900.80
ADediting_1587649ENST00000428414.5chr7_45729025_-1107-569.60-569.60-569.60

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Relation with ADAR for SEPTIN7P2

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
CERADediting_1334331chr7_45725170_-0.03323743766679340.1739760709477122.90402328618156e-050.3342893445458350.01579631427906840.196783916108228
CERADediting_1334332chr7_45725233_-0.02045886313361570.1891204964838714.1210569528207e-050.3282331430499340.0001620980743005510.303217279351592
CERADediting_1334333chr7_45725239_-0.02880050849305850.1785596456063243.29023696329771e-050.3321434321911212.5624769091987e-050.336423884072407
CERADediting_1334334chr7_45725248_-0.0133729759635270.201583504497430.0001623300033922830.3031899649309310.0003845969121080170.286197868877879
CERADediting_1334335chr7_45725258_-0.004970598252090910.2282227910361923.79449651830732e-060.3672131551446586.83700893286172e-050.31924128247956
DLPFCADediting_1334347chr7_45740132_-0.6524216775890890.02568055372085760.0701361761151175-0.1030019642228341.82082042941519e-090.333062970018385
DLPFCADediting_1334353chr7_45740201_-0.0141688945506174-0.1392017611297917.4046362529716e-05-0.2231345500676994.28367859109221e-080.304959974651276
DLPFCADediting_1334367chr7_45741180_-0.271845642444635-0.06260056750555480.0136378224516402-0.1399722077554822.68848761363963e-090.32974719584336
DLPFCADediting_1334370chr7_45741189_-0.993990597278923-0.0004295092157554330.0192852598142447-0.1328484818561421.38948387250278e-170.459310372870248
DLPFCADediting_1334371chr7_45741197_-0.158635659624738-0.08025917773291480.00248538550461011-0.1712359757729591.01469412964947e-120.390279404455318
DLPFCADediting_1334379chr7_45742102_-0.540307592369795-0.03490944787043620.0431949043171964-0.1149152389149951.47473473333004e-090.334840328758232

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC8.26781629289029e-310.5928625509116931.28952575018632e-400.6629748962735098.8494356818188e-110.357543415549823
AC7.00372101954823e-320.6538780545235373.20533706022301e-300.6401013342387661.39853549363649e-160.491091376245993
PCC4.22009476913964e-200.6005109764675273.1252613281985e-200.6021827573093591.03998799106818e-070.373353300091891
CER3.1305238985713e-090.4601758834274510.006223211181794950.2224310137920760.103442936263105-0.133478172420554
TCX9.38949436838745e-140.5599217629941758.60689828227539e-070.3891093624949323.67844226794134e-050.330213076645408
FP1.23033093734703e-250.6813698608882284.0740873140734e-310.7317522770866960.0426995425330240.152089539943069
IFG1.89657038973289e-060.7965933026569980.001032719334044770.6164419352785310.01393122135605630.485295717962896
PG1.22485721315747e-400.7881417045887479.03544896868232e-270.6817642893676860.814765360915468-0.0172937532917428
STG5.73894377786536e-190.7881620351950556.66833442868832e-160.7420765566755360.2563448655489870.125234778478698

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Relation with AD stages for SEPTIN7P2

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
CERADediting_1334332chr7_45725233_-0.0001320044817345030.3596368769569
CERADediting_1334333chr7_45725239_-0.0003647487002416820.33682119903598
CERADediting_1334335chr7_45725258_-0.0001825190419928190.352549276684458

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.

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RelatedDrugs for SEPTIN7P2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for SEPTIN7P2

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource