ADeditome: functional annotation of RNA A-to-I editing in AD

Gene summary for RPS3

Gene summary

Gene information	Gene symbol	RPS3
	Gene ID	6188
	Gene name	ribosomal protein S3
	Synonyms	S3
	Cytomap	11q13.4
	Type of gene	protein-coding
	Description	40S ribosomal protein S3IMR-90 ribosomal protein S3small ribosomal subunit protein uS3
	Modification date	20200327
	UniProtAcc	P23396,
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
RPS3	GO:0006979	response to oxidative stress	23911537
RPS3	GO:0017148	negative regulation of translation	20217897
RPS3	GO:0031397	negative regulation of protein ubiquitination	19656744
RPS3	GO:0032079	positive regulation of endodeoxyribonuclease activity	18973764
RPS3	GO:0042769	DNA damage response, detection of DNA damage	23911537
RPS3	GO:0045739	positive regulation of DNA repair	23911537
RPS3	GO:0061481	response to TNF agonist	20041225
RPS3	GO:0070301	cellular response to hydrogen peroxide	23911537
RPS3	GO:1901224	positive regulation of NIK/NF-kappaB signaling	20041225
RPS3	GO:1902546	positive regulation of DNA N-glycosylase activity	15518571
RPS3	GO:1905053	positive regulation of base-excision repair	18973764
RPS3	GO:2001235	positive regulation of apoptotic signaling pathway	14988002

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RNA A-to-I events for RPS3

RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA editing frequencies across three data sets.

The number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA A-to-I editing events in AD.

ADediting_282541(75407677, +), ADediting_282542(75407729, +), ADediting_282543(75408241, +), ADediting_282544(75408248, +), ADediting_282545(75408269, +), ADediting_282546(75408270, +), ADediting_282547(75408274, +), ADediting_282548(75408296, +), ADediting_282549(75408307, +), ADediting_282550(75408636, +), ADediting_282551(75408685, +), ADediting_282552(75408768, +), ADediting_282553(75409004, +), ADediting_282554(75409042, +), ADediting_282555(75409062, +), ADediting_282556(75409082, +), ADediting_282557(75409094, +), ADediting_282558(75409099, +), ADediting_282559(75410994, +), ADediting_282560(75411006, +), ADediting_282561(75411016, +), ADediting_282562(75411018, +), ADediting_282563(75411029, +), ADediting_282564(75411042, +), ADediting_282565(75411061, +), ADediting_282566(75411083, +), ADediting_282567(75411087, +), ADediting_282568(75411150, +), ADediting_282569(75411184, +), ADediting_282570(75411192, +), ADediting_282571(75411195, +), ADediting_282572(75411209, +), ADediting_282573(75411212, +), ADediting_282574(75411221, +), ADediting_282575(75411248, +), ADediting_282576(75411274, +), ADediting_282577(75411329, +), ADediting_282578(75411454, +), ADediting_282579(75411529, +), ADediting_282580(75411572, +), ADediting_282581(75411597, +), ADediting_282582(75411664, +), ADediting_282583(75412813, +), ADediting_282584(75412846, +), ADediting_282585(75412870, +), ADediting_282586(75412933, +), ADediting_282587(75412937, +), ADediting_282588(75413034, +), ADediting_282589(75413035, +), ADediting_282590(75413272, +), ADediting_282591(75413337, +), ADediting_282592(75413386, +), ADediting_282593(75413441, +), ADediting_282594(75413463, +), ADediting_282595(75413517, +), ADediting_282596(75413530, +), ADediting_282597(75414356, +), ADediting_282598(75414464, +), ADediting_282599(75414468, +), ADediting_282600(75414490, +), ADediting_282601(75415466, +), ADediting_282602(75415486, +), ADediting_282603(75415487, +), ADediting_282604(75415497, +), ADediting_282605(75415511, +), ADediting_282606(75415512, +), ADediting_282607(75415550, +), ADediting_282608(75415553, +), ADediting_282609(75415620, +), ADediting_282610(75415659, +), ADediting_282611(75415685, +), ADediting_282612(75415695, +), ADediting_282613(75415738, +), ADediting_282614(75415751, +), ADediting_282615(75415771, +), ADediting_282616(75415789, +), ADediting_282617(75415855, +), ADediting_282618(75415856, +), ADediting_282619(75415888, +), ADediting_282620(75415896, +), ADediting_282621(75415897, +), ADediting_282622(75415904, +), ADediting_282623(75415921, +), ADediting_282624(75415941, +), ADediting_282625(75416512, +), ADediting_282626(75416528, +), ADediting_282627(75416559, +), ADediting_282628(75416576, +), ADediting_282629(75416588, +), ADediting_282630(75416598, +), ADediting_282631(75416625, +), ADediting_282632(75416631, +), ADediting_282633(75416638, +), ADediting_282634(75416641, +), ADediting_282635(75416655, +), ADediting_282636(75416658, +), ADediting_282637(75416667, +), ADediting_282638(75416710, +), ADediting_282639(75417206, +), ADediting_282640(75417220, +), ADediting_282641(75417238, +), ADediting_282642(75417260, +), ADediting_282643(75417288, +), ADediting_282644(75417320, +), ADediting_282645(75417342, +), ADediting_282646(75417343, +), ADediting_282647(75417348, +), ADediting_282648(75417380, +), ADediting_282649(75417385, +), ADediting_282651(75417408, +), ADediting_282652(75417415, +), ADediting_282653(75417416, +), ADediting_282654(75417476, +), ADediting_282655(75417503, +), ADediting_282656(75417509, +), ADediting_282657(75417517, +), ADediting_282658(75417518, +), ADediting_282659(75417536, +), ADediting_282661(75419347, +), ADediting_282662(75419368, +), ADediting_282663(75419378, +), ADediting_282664(75419389, +), ADediting_282665(75419392, +), ADediting_282666(75419393, +), ADediting_282667(75419394, +), ADediting_282668(75419395, +), ADediting_282669(75419398, +), ADediting_282671(75419401, +), ADediting_282672(75419407, +), ADediting_282673(75419427, +), ADediting_282674(75419433, +), ADediting_282675(75419434, +), ADediting_282676(75419443, +), ADediting_282677(75419446, +), ADediting_282678(75419460, +), ADediting_282679(75419463, +), ADediting_282680(75419474, +), ADediting_282681(75419479, +), ADediting_282682(75419480, +), ADediting_282683(75419533, +), ADediting_282684(75419687, +), ADediting_282685(75419693, +), ADediting_282686(75419695, +), ADediting_282687(75419708, +), ADediting_282688(75419720, +), ADediting_282689(75419727, +), ADediting_282690(75419733, +), ADediting_282691(75419734, +), ADediting_282692(75419738, +), ADediting_282693(75419751, +), ADediting_282694(75419763, +), ADediting_282695(75419773, +), ADediting_282696(75419779, +), ADediting_282697(75419799, +), ADediting_282698(75419800, +), ADediting_282699(75419808, +), ADediting_282700(75419814, +), ADediting_282701(75419817, +), ADediting_282702(75419824, +), ADediting_282703(75419839, +), ADediting_282704(75419843, +), ADediting_282705(75419862, +), ADediting_282706(75419868, +), ADediting_282707(75419881, +), ADediting_282708(75419899, +), ADediting_1528811(75408256, +), ADediting_1528812(75408295, +), ADediting_1528813(75408565, +), ADediting_1528814(75408675, +), ADediting_1528815(75408735, +), ADediting_1528816(75409002, +), ADediting_1528817(75410866, +), ADediting_1528818(75411272, +), ADediting_1528819(75411464, +), ADediting_1528820(75412841, +), ADediting_1528821(75412892, +), ADediting_1528822(75412929, +), ADediting_1528823(75413047, +), ADediting_1528824(75414357, +), ADediting_1528825(75415514, +), ADediting_1528826(75415517, +), ADediting_1528827(75415520, +), ADediting_1528828(75415552, +), ADediting_1528829(75415575, +), ADediting_1528830(75415917, +), ADediting_1528831(75416719, +), ADediting_1528832(75416720, +), ADediting_1528833(75417215, +), ADediting_1528834(75417239, +), ADediting_1528835(75417255, +), ADediting_1528836(75417268, +), ADediting_1528837(75417269, +), ADediting_1528838(75417275, +), ADediting_1528839(75417284, +), ADediting_1528840(75417299, +), ADediting_1528841(75417418, +), ADediting_1528842(75417620, +), ADediting_1528843(75419423, +), ADediting_1528844(75419873, +),

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RNA editing positional annotations for RPS3 using Annovar

Protein coding RNA editing(s).

ADeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

ADeditome ID	Position	Variant type
ADediting_282541	chr11_75407677_+	intronic
ADediting_282542	chr11_75407729_+	intronic
ADediting_282543	chr11_75408241_+	intronic
ADediting_282544	chr11_75408248_+	intronic
ADediting_282545	chr11_75408269_+	intronic
ADediting_282546	chr11_75408270_+	intronic
ADediting_282547	chr11_75408274_+	intronic
ADediting_282548	chr11_75408296_+	intronic
ADediting_282549	chr11_75408307_+	intronic
ADediting_282550	chr11_75408636_+	intronic
ADediting_282551	chr11_75408685_+	intronic
ADediting_282552	chr11_75408768_+	intronic
ADediting_282553	chr11_75409004_+	intronic
ADediting_282554	chr11_75409042_+	intronic
ADediting_282555	chr11_75409062_+	intronic
ADediting_282556	chr11_75409082_+	intronic
ADediting_282557	chr11_75409094_+	intronic
ADediting_282558	chr11_75409099_+	intronic
ADediting_282559	chr11_75410994_+	intronic
ADediting_282560	chr11_75411006_+	intronic
ADediting_282561	chr11_75411016_+	intronic
ADediting_282562	chr11_75411018_+	intronic
ADediting_282563	chr11_75411029_+	intronic
ADediting_282564	chr11_75411042_+	intronic
ADediting_282565	chr11_75411061_+	intronic
ADediting_282566	chr11_75411083_+	intronic
ADediting_282567	chr11_75411087_+	intronic
ADediting_282568	chr11_75411150_+	intronic
ADediting_282569	chr11_75411184_+	intronic
ADediting_282570	chr11_75411192_+	intronic
ADediting_282571	chr11_75411195_+	intronic
ADediting_282572	chr11_75411209_+	intronic
ADediting_282573	chr11_75411212_+	intronic
ADediting_282574	chr11_75411221_+	intronic
ADediting_282575	chr11_75411248_+	intronic
ADediting_282576	chr11_75411274_+	intronic
ADediting_282577	chr11_75411329_+	intronic
ADediting_282578	chr11_75411454_+	intronic
ADediting_282579	chr11_75411529_+	intronic
ADediting_282580	chr11_75411572_+	intronic
ADediting_282581	chr11_75411597_+	intronic
ADediting_282582	chr11_75411664_+	intronic
ADediting_282583	chr11_75412813_+	intronic
ADediting_282584	chr11_75412846_+	intronic
ADediting_282585	chr11_75412870_+	intronic
ADediting_282586	chr11_75412933_+	intronic
ADediting_282587	chr11_75412937_+	intronic
ADediting_282588	chr11_75413034_+	intronic
ADediting_282589	chr11_75413035_+	intronic
ADediting_282590	chr11_75413272_+	intronic
ADediting_282591	chr11_75413337_+	intronic
ADediting_282592	chr11_75413386_+	intronic
ADediting_282593	chr11_75413441_+	intronic
ADediting_282594	chr11_75413463_+	intronic
ADediting_282595	chr11_75413517_+	intronic
ADediting_282596	chr11_75413530_+	intronic
ADediting_282597	chr11_75414356_+	intronic
ADediting_282598	chr11_75414464_+	intronic
ADediting_282599	chr11_75414468_+	intronic
ADediting_282600	chr11_75414490_+	intronic
ADediting_282601	chr11_75415466_+	intronic
ADediting_282602	chr11_75415486_+	intronic
ADediting_282603	chr11_75415487_+	intronic
ADediting_282604	chr11_75415497_+	intronic
ADediting_282605	chr11_75415511_+	intronic
ADediting_282606	chr11_75415512_+	intronic
ADediting_282607	chr11_75415550_+	intronic
ADediting_282608	chr11_75415553_+	intronic
ADediting_282609	chr11_75415620_+	intronic
ADediting_282610	chr11_75415659_+	intronic
ADediting_282611	chr11_75415685_+	intronic
ADediting_282612	chr11_75415695_+	intronic
ADediting_282613	chr11_75415738_+	intronic
ADediting_282614	chr11_75415751_+	intronic
ADediting_282615	chr11_75415771_+	intronic
ADediting_282616	chr11_75415789_+	intronic
ADediting_282617	chr11_75415855_+	intronic
ADediting_282618	chr11_75415856_+	intronic
ADediting_282619	chr11_75415888_+	intronic
ADediting_282620	chr11_75415896_+	intronic
ADediting_282621	chr11_75415897_+	intronic
ADediting_282622	chr11_75415904_+	intronic
ADediting_282623	chr11_75415921_+	intronic
ADediting_282624	chr11_75415941_+	intronic
ADediting_282625	chr11_75416512_+	intronic
ADediting_282626	chr11_75416528_+	intronic
ADediting_282627	chr11_75416559_+	intronic
ADediting_282628	chr11_75416576_+	intronic
ADediting_282629	chr11_75416588_+	intronic
ADediting_282630	chr11_75416598_+	intronic
ADediting_282631	chr11_75416625_+	intronic
ADediting_282632	chr11_75416631_+	intronic
ADediting_282633	chr11_75416638_+	intronic
ADediting_282634	chr11_75416641_+	intronic
ADediting_282635	chr11_75416655_+	intronic
ADediting_282636	chr11_75416658_+	intronic
ADediting_282637	chr11_75416667_+	intronic
ADediting_282638	chr11_75416710_+	intronic
ADediting_282639	chr11_75417206_+	intronic
ADediting_282640	chr11_75417220_+	intronic
ADediting_282641	chr11_75417238_+	intronic
ADediting_282642	chr11_75417260_+	intronic
ADediting_282643	chr11_75417288_+	intronic
ADediting_282644	chr11_75417320_+	intronic
ADediting_282645	chr11_75417342_+	intronic
ADediting_282646	chr11_75417343_+	intronic
ADediting_282647	chr11_75417348_+	intronic
ADediting_282648	chr11_75417380_+	intronic
ADediting_282649	chr11_75417385_+	intronic
ADediting_282651	chr11_75417408_+	intronic
ADediting_282652	chr11_75417415_+	intronic
ADediting_282653	chr11_75417416_+	intronic
ADediting_282654	chr11_75417476_+	intronic
ADediting_282655	chr11_75417503_+	intronic
ADediting_282656	chr11_75417509_+	intronic
ADediting_282657	chr11_75417517_+	intronic
ADediting_282658	chr11_75417518_+	intronic
ADediting_282659	chr11_75417536_+	intronic
ADediting_282661	chr11_75419347_+	intronic
ADediting_282662	chr11_75419368_+	intronic
ADediting_282663	chr11_75419378_+	intronic
ADediting_282664	chr11_75419389_+	intronic
ADediting_282665	chr11_75419392_+	intronic
ADediting_282666	chr11_75419393_+	intronic
ADediting_282667	chr11_75419394_+	intronic
ADediting_282668	chr11_75419395_+	intronic
ADediting_282669	chr11_75419398_+	intronic
ADediting_282671	chr11_75419401_+	intronic
ADediting_282672	chr11_75419407_+	intronic
ADediting_282673	chr11_75419427_+	intronic
ADediting_282674	chr11_75419433_+	intronic
ADediting_282675	chr11_75419434_+	intronic
ADediting_282676	chr11_75419443_+	intronic
ADediting_282677	chr11_75419446_+	intronic
ADediting_282678	chr11_75419460_+	intronic
ADediting_282679	chr11_75419463_+	intronic
ADediting_282680	chr11_75419474_+	intronic
ADediting_282681	chr11_75419479_+	intronic
ADediting_282682	chr11_75419480_+	intronic
ADediting_282683	chr11_75419533_+	intronic
ADediting_282684	chr11_75419687_+	intronic
ADediting_282685	chr11_75419693_+	intronic
ADediting_282686	chr11_75419695_+	intronic
ADediting_282687	chr11_75419708_+	intronic
ADediting_282688	chr11_75419720_+	intronic
ADediting_282689	chr11_75419727_+	intronic
ADediting_282690	chr11_75419733_+	intronic
ADediting_282691	chr11_75419734_+	intronic
ADediting_282692	chr11_75419738_+	intronic
ADediting_282693	chr11_75419751_+	intronic
ADediting_282694	chr11_75419763_+	intronic
ADediting_282695	chr11_75419773_+	intronic
ADediting_282696	chr11_75419779_+	intronic
ADediting_282697	chr11_75419799_+	intronic
ADediting_282698	chr11_75419800_+	intronic
ADediting_282699	chr11_75419808_+	intronic
ADediting_282700	chr11_75419814_+	intronic
ADediting_282701	chr11_75419817_+	intronic
ADediting_282702	chr11_75419824_+	intronic
ADediting_282703	chr11_75419839_+	intronic
ADediting_282704	chr11_75419843_+	intronic
ADediting_282705	chr11_75419862_+	intronic
ADediting_282706	chr11_75419868_+	intronic
ADediting_282707	chr11_75419881_+	intronic
ADediting_282708	chr11_75419899_+	intronic
ADediting_1528811	chr11_75408256_+	intronic
ADediting_1528812	chr11_75408295_+	intronic
ADediting_1528813	chr11_75408565_+	intronic
ADediting_1528814	chr11_75408675_+	intronic
ADediting_1528815	chr11_75408735_+	intronic
ADediting_1528816	chr11_75409002_+	intronic
ADediting_1528817	chr11_75410866_+	intronic
ADediting_1528818	chr11_75411272_+	intronic
ADediting_1528819	chr11_75411464_+	intronic
ADediting_1528820	chr11_75412841_+	intronic
ADediting_1528821	chr11_75412892_+	intronic
ADediting_1528822	chr11_75412929_+	intronic
ADediting_1528823	chr11_75413047_+	intronic
ADediting_1528824	chr11_75414357_+	intronic
ADediting_1528825	chr11_75415514_+	intronic
ADediting_1528826	chr11_75415517_+	intronic
ADediting_1528827	chr11_75415520_+	intronic
ADediting_1528828	chr11_75415552_+	intronic
ADediting_1528829	chr11_75415575_+	intronic
ADediting_1528830	chr11_75415917_+	intronic
ADediting_1528831	chr11_75416719_+	intronic
ADediting_1528832	chr11_75416720_+	intronic
ADediting_1528833	chr11_75417215_+	intronic
ADediting_1528834	chr11_75417239_+	intronic
ADediting_1528835	chr11_75417255_+	intronic
ADediting_1528836	chr11_75417268_+	intronic
ADediting_1528837	chr11_75417269_+	intronic
ADediting_1528838	chr11_75417275_+	intronic
ADediting_1528839	chr11_75417284_+	intronic
ADediting_1528840	chr11_75417299_+	intronic
ADediting_1528841	chr11_75417418_+	intronic
ADediting_1528842	chr11_75417620_+	intronic
ADediting_1528843	chr11_75419423_+	intronic
ADediting_1528844	chr11_75419873_+	intronic

Repat-regional RNA editing(s).

ADeditome ID	Position	Repeat family	Repeat sub family	Repeat name
ADediting_282541	chr11_75407677_+	SINE	Alu	Name=AluY
ADediting_282542	chr11_75407729_+	SINE	Alu	Name=AluY
ADediting_282543	chr11_75408241_+	SINE	Alu	Name=AluJb
ADediting_282544	chr11_75408248_+	SINE	Alu	Name=AluJb
ADediting_282545	chr11_75408269_+	SINE	Alu	Name=AluJb
ADediting_282546	chr11_75408270_+	SINE	Alu	Name=AluJb
ADediting_282547	chr11_75408274_+	SINE	Alu	Name=AluJb
ADediting_282548	chr11_75408296_+	SINE	Alu	Name=AluJb
ADediting_282549	chr11_75408307_+	SINE	Alu	Name=AluJb
ADediting_282550	chr11_75408636_+	SINE	Alu	Name=AluSx1
ADediting_282551	chr11_75408685_+	SINE	Alu	Name=AluSx1
ADediting_282552	chr11_75408768_+	SINE	Alu	Name=AluSx1
ADediting_282553	chr11_75409004_+	SINE	Alu	Name=AluJr
ADediting_282554	chr11_75409042_+	SINE	Alu	Name=AluJr
ADediting_282555	chr11_75409062_+	SINE	Alu	Name=AluJr
ADediting_282556	chr11_75409082_+	SINE	Alu	Name=AluJr
ADediting_282557	chr11_75409094_+	SINE	Alu	Name=AluJr
ADediting_282558	chr11_75409099_+	SINE	Alu	Name=AluJr
ADediting_282559	chr11_75410994_+	SINE	Alu	Name=AluY
ADediting_282560	chr11_75411006_+	SINE	Alu	Name=AluY
ADediting_282561	chr11_75411016_+	SINE	Alu	Name=AluY
ADediting_282562	chr11_75411018_+	SINE	Alu	Name=AluY
ADediting_282563	chr11_75411029_+	SINE	Alu	Name=AluY
ADediting_282564	chr11_75411042_+	SINE	Alu	Name=AluY
ADediting_282565	chr11_75411061_+	SINE	Alu	Name=AluY
ADediting_282566	chr11_75411083_+	SINE	Alu	Name=AluY
ADediting_282567	chr11_75411087_+	SINE	Alu	Name=AluY
ADediting_282568	chr11_75411150_+	SINE	Alu	Name=AluY
ADediting_282569	chr11_75411184_+	SINE	Alu	Name=AluSz
ADediting_282570	chr11_75411192_+	SINE	Alu	Name=AluSz
ADediting_282571	chr11_75411195_+	SINE	Alu	Name=AluSz
ADediting_282572	chr11_75411209_+	SINE	Alu	Name=AluSz
ADediting_282573	chr11_75411212_+	SINE	Alu	Name=AluSz
ADediting_282574	chr11_75411221_+	SINE	Alu	Name=AluSz
ADediting_282575	chr11_75411248_+	SINE	Alu	Name=AluSz
ADediting_282576	chr11_75411274_+	SINE	Alu	Name=AluSz
ADediting_282578	chr11_75411454_+	SINE	Alu	Name=AluY
ADediting_282579	chr11_75411529_+	SINE	Alu	Name=AluY
ADediting_282580	chr11_75411572_+	SINE	Alu	Name=AluY
ADediting_282581	chr11_75411597_+	SINE	Alu	Name=AluY
ADediting_282582	chr11_75411664_+	SINE	Alu	Name=AluY
ADediting_282583	chr11_75412813_+	SINE	Alu	Name=AluSz6
ADediting_282584	chr11_75412846_+	SINE	Alu	Name=AluSz6
ADediting_282585	chr11_75412870_+	SINE	Alu	Name=AluSz6
ADediting_282586	chr11_75412933_+	SINE	Alu	Name=AluSz6
ADediting_282587	chr11_75412937_+	SINE	Alu	Name=AluSz6
ADediting_282588	chr11_75413034_+	SINE	Alu	Name=AluSz6
ADediting_282589	chr11_75413035_+	SINE	Alu	Name=AluSz6
ADediting_282590	chr11_75413272_+	SINE	Alu	Name=AluY
ADediting_282591	chr11_75413337_+	SINE	Alu	Name=AluY
ADediting_282592	chr11_75413386_+	SINE	Alu	Name=AluY
ADediting_282593	chr11_75413441_+	SINE	Alu	Name=AluY
ADediting_282594	chr11_75413463_+	SINE	Alu	Name=AluY
ADediting_282595	chr11_75413517_+	SINE	Alu	Name=AluY
ADediting_282596	chr11_75413530_+	SINE	Alu	Name=AluY
ADediting_282597	chr11_75414356_+	SINE	Alu	Name=AluY
ADediting_282598	chr11_75414464_+	SINE	Alu	Name=AluY
ADediting_282599	chr11_75414468_+	SINE	Alu	Name=AluY
ADediting_282600	chr11_75414490_+	SINE	Alu	Name=AluY
ADediting_282601	chr11_75415466_+	SINE	Alu	Name=AluSz6
ADediting_282602	chr11_75415486_+	SINE	Alu	Name=AluSz6
ADediting_282603	chr11_75415487_+	SINE	Alu	Name=AluSz6
ADediting_282604	chr11_75415497_+	SINE	Alu	Name=AluSz6
ADediting_282605	chr11_75415511_+	SINE	Alu	Name=AluSz6
ADediting_282606	chr11_75415512_+	SINE	Alu	Name=AluSz6
ADediting_282607	chr11_75415550_+	SINE	Alu	Name=AluSg4
ADediting_282608	chr11_75415553_+	SINE	Alu	Name=AluSg4
ADediting_282609	chr11_75415620_+	SINE	Alu	Name=AluSg4
ADediting_282610	chr11_75415659_+	SINE	Alu	Name=AluSg4
ADediting_282611	chr11_75415685_+	SINE	Alu	Name=AluSg4
ADediting_282612	chr11_75415695_+	SINE	Alu	Name=AluSg4
ADediting_282613	chr11_75415738_+	SINE	Alu	Name=AluSg4
ADediting_282614	chr11_75415751_+	SINE	Alu	Name=AluSg4
ADediting_282615	chr11_75415771_+	SINE	Alu	Name=AluSg4
ADediting_282616	chr11_75415789_+	SINE	Alu	Name=AluSg4
ADediting_282617	chr11_75415855_+	SINE	Alu	Name=AluSz6
ADediting_282618	chr11_75415856_+	SINE	Alu	Name=AluSz6
ADediting_282619	chr11_75415888_+	SINE	Alu	Name=AluSz6
ADediting_282620	chr11_75415896_+	SINE	Alu	Name=AluSz6
ADediting_282621	chr11_75415897_+	SINE	Alu	Name=AluSz6
ADediting_282622	chr11_75415904_+	SINE	Alu	Name=AluSz6
ADediting_282623	chr11_75415921_+	SINE	Alu	Name=AluSz6
ADediting_282624	chr11_75415941_+	SINE	Alu	Name=AluSz6
ADediting_282625	chr11_75416512_+	SINE	Alu	Name=AluSx
ADediting_282626	chr11_75416528_+	SINE	Alu	Name=AluSx
ADediting_282627	chr11_75416559_+	SINE	Alu	Name=AluSx
ADediting_282628	chr11_75416576_+	SINE	Alu	Name=AluSx
ADediting_282629	chr11_75416588_+	SINE	Alu	Name=AluSx
ADediting_282630	chr11_75416598_+	SINE	Alu	Name=AluSx
ADediting_282631	chr11_75416625_+	SINE	Alu	Name=AluSx
ADediting_282632	chr11_75416631_+	SINE	Alu	Name=AluSx
ADediting_282633	chr11_75416638_+	SINE	Alu	Name=AluSx
ADediting_282634	chr11_75416641_+	SINE	Alu	Name=AluSx
ADediting_282635	chr11_75416655_+	SINE	Alu	Name=AluSx
ADediting_282636	chr11_75416658_+	SINE	Alu	Name=AluSx
ADediting_282637	chr11_75416667_+	SINE	Alu	Name=AluSx
ADediting_282638	chr11_75416710_+	SINE	Alu	Name=AluSx
ADediting_282639	chr11_75417206_+	SINE	Alu	Name=AluJr
ADediting_282640	chr11_75417220_+	SINE	Alu	Name=AluJr
ADediting_282641	chr11_75417238_+	SINE	Alu	Name=AluJr
ADediting_282642	chr11_75417260_+	SINE	Alu	Name=AluJr
ADediting_282643	chr11_75417288_+	SINE	Alu	Name=AluJr
ADediting_282644	chr11_75417320_+	SINE	Alu	Name=AluY
ADediting_282645	chr11_75417342_+	SINE	Alu	Name=AluY
ADediting_282646	chr11_75417343_+	SINE	Alu	Name=AluY
ADediting_282647	chr11_75417348_+	SINE	Alu	Name=AluY
ADediting_282648	chr11_75417380_+	SINE	Alu	Name=AluY
ADediting_282649	chr11_75417385_+	SINE	Alu	Name=AluY
ADediting_282651	chr11_75417408_+	SINE	Alu	Name=AluY
ADediting_282652	chr11_75417415_+	SINE	Alu	Name=AluY
ADediting_282653	chr11_75417416_+	SINE	Alu	Name=AluY
ADediting_282654	chr11_75417476_+	SINE	Alu	Name=AluY
ADediting_282655	chr11_75417503_+	SINE	Alu	Name=AluY
ADediting_282656	chr11_75417509_+	SINE	Alu	Name=AluY
ADediting_282657	chr11_75417517_+	SINE	Alu	Name=AluY
ADediting_282658	chr11_75417518_+	SINE	Alu	Name=AluY
ADediting_282659	chr11_75417536_+	SINE	Alu	Name=AluY
ADediting_282661	chr11_75419347_+	SINE	Alu	Name=AluSx
ADediting_282662	chr11_75419368_+	SINE	Alu	Name=AluSx
ADediting_282663	chr11_75419378_+	SINE	Alu	Name=AluSx
ADediting_282664	chr11_75419389_+	SINE	Alu	Name=AluSx
ADediting_282665	chr11_75419392_+	SINE	Alu	Name=AluSx
ADediting_282666	chr11_75419393_+	SINE	Alu	Name=AluSx
ADediting_282667	chr11_75419394_+	SINE	Alu	Name=AluSx
ADediting_282668	chr11_75419395_+	SINE	Alu	Name=AluSx
ADediting_282669	chr11_75419398_+	SINE	Alu	Name=AluSx
ADediting_282671	chr11_75419401_+	SINE	Alu	Name=AluSx
ADediting_282672	chr11_75419407_+	SINE	Alu	Name=AluSx
ADediting_282673	chr11_75419427_+	SINE	Alu	Name=AluSx
ADediting_282674	chr11_75419433_+	SINE	Alu	Name=AluSx
ADediting_282675	chr11_75419434_+	SINE	Alu	Name=AluSx
ADediting_282676	chr11_75419443_+	SINE	Alu	Name=AluSx
ADediting_282677	chr11_75419446_+	SINE	Alu	Name=AluSx
ADediting_282678	chr11_75419460_+	SINE	Alu	Name=AluSx
ADediting_282679	chr11_75419463_+	SINE	Alu	Name=AluSx
ADediting_282680	chr11_75419474_+	SINE	Alu	Name=AluSx
ADediting_282681	chr11_75419479_+	SINE	Alu	Name=AluSx
ADediting_282682	chr11_75419480_+	SINE	Alu	Name=AluSx
ADediting_282683	chr11_75419533_+	SINE	Alu	Name=AluSx
ADediting_282684	chr11_75419687_+	SINE	Alu	Name=AluSx
ADediting_282685	chr11_75419693_+	SINE	Alu	Name=AluSx
ADediting_282686	chr11_75419695_+	SINE	Alu	Name=AluSx
ADediting_282687	chr11_75419708_+	SINE	Alu	Name=AluSx
ADediting_282688	chr11_75419720_+	SINE	Alu	Name=AluSx
ADediting_282689	chr11_75419727_+	SINE	Alu	Name=AluSx
ADediting_282690	chr11_75419733_+	SINE	Alu	Name=AluSx
ADediting_282691	chr11_75419734_+	SINE	Alu	Name=AluSx
ADediting_282692	chr11_75419738_+	SINE	Alu	Name=AluSx
ADediting_282693	chr11_75419751_+	SINE	Alu	Name=AluSx
ADediting_282694	chr11_75419763_+	SINE	Alu	Name=AluSx
ADediting_282695	chr11_75419773_+	SINE	Alu	Name=AluSx
ADediting_282696	chr11_75419779_+	SINE	Alu	Name=AluSx
ADediting_282697	chr11_75419799_+	SINE	Alu	Name=AluSx
ADediting_282698	chr11_75419800_+	SINE	Alu	Name=AluSx
ADediting_282699	chr11_75419808_+	SINE	Alu	Name=AluSx
ADediting_282700	chr11_75419814_+	SINE	Alu	Name=AluSx
ADediting_282701	chr11_75419817_+	SINE	Alu	Name=AluSx
ADediting_282702	chr11_75419824_+	SINE	Alu	Name=AluSx
ADediting_282703	chr11_75419839_+	SINE	Alu	Name=AluSx
ADediting_282704	chr11_75419843_+	SINE	Alu	Name=AluSx
ADediting_282705	chr11_75419862_+	SINE	Alu	Name=AluSx
ADediting_282706	chr11_75419868_+	SINE	Alu	Name=AluSx
ADediting_282707	chr11_75419881_+	SINE	Alu	Name=AluSx
ADediting_282708	chr11_75419899_+	SINE	Alu	Name=AluSx
ADediting_1528811	chr11_75408256_+	SINE	Alu	Name=AluJb
ADediting_1528812	chr11_75408295_+	SINE	Alu	Name=AluJb
ADediting_1528813	chr11_75408565_+	SINE	Alu	Name=AluJo
ADediting_1528814	chr11_75408675_+	SINE	Alu	Name=AluSx1
ADediting_1528815	chr11_75408735_+	SINE	Alu	Name=AluSx1
ADediting_1528816	chr11_75409002_+	SINE	Alu	Name=AluJr
ADediting_1528817	chr11_75410866_+	Retroposon	SVA	Name=SVA_E
ADediting_1528818	chr11_75411272_+	SINE	Alu	Name=AluSz
ADediting_1528819	chr11_75411464_+	SINE	Alu	Name=AluY
ADediting_1528820	chr11_75412841_+	SINE	Alu	Name=AluSz6
ADediting_1528821	chr11_75412892_+	SINE	Alu	Name=AluSz6
ADediting_1528822	chr11_75412929_+	SINE	Alu	Name=AluSz6
ADediting_1528823	chr11_75413047_+	SINE	Alu	Name=AluSz6
ADediting_1528824	chr11_75414357_+	SINE	Alu	Name=AluY
ADediting_1528825	chr11_75415514_+	SINE	Alu	Name=AluSz6
ADediting_1528826	chr11_75415517_+	SINE	Alu	Name=AluSz6
ADediting_1528827	chr11_75415520_+	SINE	Alu	Name=AluSz6
ADediting_1528828	chr11_75415552_+	SINE	Alu	Name=AluSg4
ADediting_1528829	chr11_75415575_+	SINE	Alu	Name=AluSg4
ADediting_1528830	chr11_75415917_+	SINE	Alu	Name=AluSz6
ADediting_1528831	chr11_75416719_+	SINE	Alu	Name=AluSx
ADediting_1528832	chr11_75416720_+	SINE	Alu	Name=AluSx
ADediting_1528833	chr11_75417215_+	SINE	Alu	Name=AluJr
ADediting_1528834	chr11_75417239_+	SINE	Alu	Name=AluJr
ADediting_1528835	chr11_75417255_+	SINE	Alu	Name=AluJr
ADediting_1528836	chr11_75417268_+	SINE	Alu	Name=AluJr
ADediting_1528837	chr11_75417269_+	SINE	Alu	Name=AluJr
ADediting_1528838	chr11_75417275_+	SINE	Alu	Name=AluJr
ADediting_1528839	chr11_75417284_+	SINE	Alu	Name=AluJr
ADediting_1528840	chr11_75417299_+	SINE	Alu	Name=AluJr
ADediting_1528841	chr11_75417418_+	SINE	Alu	Name=AluY
ADediting_1528842	chr11_75417620_+	SINE	Alu	Name=AluJr
ADediting_1528843	chr11_75419423_+	SINE	Alu	Name=AluSx
ADediting_1528844	chr11_75419873_+	SINE	Alu	Name=AluSx

Top

RNA A-to-I editing events in the alternative splicing sites for RPS3

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

ADeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

Top

Differntial gene expression between RNA A-to-I edited versus non-edited samples for RPS3

Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

- Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

ADeditome ID

Chr

Positoing

Skipped exon

ENSG

ENSTs

Top

Protein coding region RNA A-to-I editings for RPS3

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

Top

The effects of the RNA editing to the miRNA binding sites for RPS3

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

ADediting_1535951

chr14_100874558_+

ENSG00000149273.15

ENST00000530164.5

RPS3-214

hsa-miR-337-3p

chr11

75402540

75402546

7mer-m8

75402526

75402547

140

-9.51

ADediting_843620

chr2_207754818_+

ENSG00000149273.15

ENST00000531188.6

RPS3-217

hsa-miR-4775

chr11

75406353

75406359

7mer-m8

75406339

75406360

141

-11.82

ADediting_98289

chr1_32086992_+

ENSG00000149273.15

ENST00000530164.5

RPS3-214

hsa-miR-5585-3p

chr11

75402884

75402890

7mer-1a

75402869

75402890

152

-16.51

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

ADediting_1337757

chr7_5495852_-

ENSG00000149273.15

ENST00000530164.5

RPS3-214

hsa-miR-589-3p

chr11

75402667

75402673

7mer-m8

75402651

75402674

148

-18.91

ADediting_1337758

chr7_5495892_-

ENSG00000149273.15

ENST00000530164.5

RPS3-214

hsa-miR-589-5p

chr11

75403221

75403228

8mer-1a

75403210

75403228

151

-20.68

ADediting_1535951

chr14_100874558_+

ENSG00000149273.15

ENST00000527446.5

RPS3-209

hsa-miR-337-3p

chr11

75422129

75422135

7mer-m8

75422115

75422136

148

-16.44

ADediting_1535953

chr14_101045971_+

ENSG00000149273.15

ENST00000524851.5

RPS3-203

hsa-miR-381-3p

chr11

75404933

75404939

7mer-m8

75404919

75404940

143

-7.46

ADediting_1535953

chr14_101045971_+

ENSG00000149273.15

ENST00000525933.1

RPS3-205

hsa-miR-381-3p

chr11

75404933

75404939

7mer-m8

75404919

75404940

143

-7.46

ADediting_1535953

chr14_101045971_+

ENSG00000149273.15

ENST00000525933.1

RPS3-205

hsa-miR-381-3p

chr11

75405454

75405460

7mer-m8

75405441

75405461

146

-14.04

ADediting_1535954

chr14_101045974_+

ENSG00000149273.15

ENST00000524851.5

RPS3-203

hsa-miR-381-3p

chr11

75404933

75404939

7mer-m8

75404919

75404940

143

-7.46

ADediting_1535954

chr14_101045974_+

ENSG00000149273.15

ENST00000525933.1

RPS3-205

hsa-miR-381-3p

chr11

75404933

75404939

7mer-m8

75404919

75404940

143

-7.46

ADediting_1535954

chr14_101045974_+

ENSG00000149273.15

ENST00000525933.1

RPS3-205

hsa-miR-381-3p

chr11

75405454

75405460

7mer-m8

75405441

75405461

146

-14.04

ADediting_291761

chr11_93733708_-

ENSG00000149273.15

ENST00000527446.5

RPS3-209

hsa-miR-1304-3p

chr11

75421771

75421777

7mer-m8

75421753

75421778

148

-14.84

Differentially expressed gene-miRNA network

Differentially expressed lncRNA-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for RPS3

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in miRNA.

ADeditom_ID

ENST

mir_ID

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

RNA A-to-I editing in mRNA.

ADeditom_ID

ENST

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

RNA A-to-I editing in lncRNA.

ADeditom_ID

ENST

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

Top

Relation with ADAR for RPS3

Correlation between ADAR gene expression and RNA editing frequency

Tissue	ADeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
CER	ADediting_282545	chr11_75408269_+	0.000112272510127599	0.310146566757376	0.00112129298632924	0.263515576291718	0.191288728831485	0.107287092383326
TCX	ADediting_282545	chr11_75408269_+	0.0144367649374103	0.199390237541846	0.000165834298365121	0.302781625679264	0.531448150217417	0.0514929530590373
CER	ADediting_282547	chr11_75408274_+	0.000794508549346865	0.271032116264316	0.000138544159142911	0.306200667536045	0.00332885974489435	0.238224224623799
TCX	ADediting_282547	chr11_75408274_+	0.0811860421406421	0.142848238117424	4.85454824562432e-05	0.325354435518453	0.409036389480354	-0.0678993561154738
CER	ADediting_282549	chr11_75408307_+	0.00156763676441752	0.255990761329313	0.000163125345158636	0.303096572299141	0.0718927858591758	0.147382112294505
CER	ADediting_282550	chr11_75408636_+	0.00139989187265767	0.258556790376705	2.57862571174369e-05	0.336317085629264	0.962753638481261	-0.00384505674070862
CER	ADediting_282552	chr11_75408768_+	7.21112089815871e-06	0.357217118521852	1.99874478303896e-05	0.340616445281511	0.00968082074832629	0.210616828881242
CER	ADediting_282554	chr11_75409042_+	2.873262431457e-08	0.434044387425985	1.05860879474062e-08	0.446087383502317	0.000394749395876288	0.285667792006289
CER	ADediting_282558	chr11_75409099_+	0.00292353646113597	0.241378239502074	0.000135677361133914	0.306595569600723	0.524921806272488	0.0523130320363637
CER	ADediting_282577	chr11_75411329_+	0.000191585707713173	0.300006011553529	0.00627271777739288	0.222224251537496	0.148334668842122	-0.118594760445421
CER	ADediting_282578	chr11_75411454_+	0.0179063332212152	0.193101909864378	4.73937295791562e-05	0.325778216724255	0.99581575355721	0.000431799272947122
DLPFC	ADediting_282583	chr11_75412813_+	0.0663838758282316	0.104404371889024	0.664367454079994	0.0247395333188776	2.20224237066036e-14	0.415710209727131
CER	ADediting_282583	chr11_75412813_+	0.000166370611773907	0.302719841747379	5.90451254173899e-05	0.321875045459443	0.647563187757987	0.0376276959839442
DLPFC	ADediting_282584	chr11_75412846_+	0.0292921100180885	0.123812642505776	0.775701395652055	0.0162472345266751	3.3623852549997e-08	0.307221207080192
CER	ADediting_282584	chr11_75412846_+	0.000157680654314098	0.303744592842149	9.50116480997418e-05	0.313240266465672	0.402058339473501	0.0689135020008432
CER	ADediting_282603	chr11_75415487_+	0.000387924796412848	0.286022703480036	7.46671668058976e-05	0.31764696613792	0.182721540739004	0.109380100230624
DLPFC	ADediting_282607	chr11_75415550_+	0.558942687268081	0.0333177896070905	0.279835390554368	-0.0615694987710496	2.33167131532267e-14	0.415346492480506
DLPFC	ADediting_282609	chr11_75415620_+	0.0510917544965713	0.110898821484643	0.846187538429175	0.0110619646271973	4.28328748444808e-14	0.41144582894862
DLPFC	ADediting_282621	chr11_75415897_+	0.709415843832663	0.0212480192191296	0.171606398572499	-0.0778404116613823	2.12681685026829e-10	0.350660377560781
CER	ADediting_282633	chr11_75416638_+	0.0023224039999043	0.246874175729571	4.78274721501121e-05	0.325617500520187	0.907782276193334	-0.0095375660640526
CER	ADediting_282634	chr11_75416641_+	0.00554038217795587	0.225443468608427	0.000139497615010408	0.30607101587676	0.739533244763224	-0.027370061893558
DLPFC	ADediting_282635	chr11_75416655_+	0.000113145752924062	0.217510706832903	0.0433319369612327	0.114840474450821	2.65279500445281e-13	0.3994355286689
CER	ADediting_282637	chr11_75416667_+	0.000595699355751841	0.277155237860183	0.000110996014679935	0.310359575702959	0.351818943088394	-0.0765500525540185
DLPFC	ADediting_282638	chr11_75416710_+	0.000805049949376702	0.189367058923549	0.228367751978206	0.068611737816128	4.23949158002628e-12	0.38019784576035
CER	ADediting_282638	chr11_75416710_+	6.72891916604478e-08	0.423397554164057	8.2419606796193e-07	0.389725562043218	0.971070154473517	-0.00298609085974243
CER	ADediting_282642	chr11_75417260_+	7.95625473371655e-05	0.316492256503232	2.96747211440573e-05	0.333919031465848	0.745184357240945	0.0267548497056348
CER	ADediting_282645	chr11_75417342_+	0.00332668118542391	0.238240228643776	0.000111787580686169	0.310227219363916	0.136961236045012	0.121996120920284
DLPFC	ADediting_282659	chr11_75417536_+	0.00753161826904375	0.151515600092627	0.304932288516275	0.0584542839770096	1.09016398981026e-16	0.447737840435341
DLPFC	ADediting_282661	chr11_75419347_+	0.501280883126177	-0.0383348769742852	0.0286905639719833	-0.124273694846734	3.34678247018911e-11	0.364987666506746
DLPFC	ADediting_282678	chr11_75419460_+	0.478282215307199	-0.0404191853350544	0.0162310545932778	-0.136431959559109	2.43228568075035e-11	0.36738988651114

Correlation between ADAR gene expression and this gene's expression

Tissue	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
DLPFC	1.37309227052293e-14	0.418702147526346	4.00582325701614e-12	0.380604234296306	5.72178105727318e-08	0.302231576531355
AC	1.22257431052607e-53	0.785662452129987	9.22438983177366e-37	0.690598689230007	8.17657691393379e-18	0.508086085843983
PCC	6.50290396468527e-06	0.319775299703456	2.35912929115792e-06	0.333863886945332	0.0152962883637281	0.175277463406709
CER	0.000483558055519361	0.281503561800509	5.55214123080727e-06	0.361327955863177	0.202930209846372	0.104549678120075
TCX	0.188081173378077	0.108062534161296	0.0121075391027301	-0.204400824966532	2.73884904440071e-13	0.551047470696455
FP	1.13538973520842e-08	0.411690691828843	1.14548262017302e-09	0.436294490629958	0.230275584707851	0.09037008731966
IFG	0.004711433644498	0.546430997009111	0.00731609767960574	0.522926995650804	0.488202333683847	0.145335971286714
PG	1.7153390074549e-07	0.371983650578694	0.0106385318492168	0.186900842665368	0.366731998890573	0.066557966766938
STG	4.45950758580582e-05	0.430008969402047	0.0161104748629376	0.261884191958147	0.956931792796203	-0.00598192566393048

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Relation with AD stages for RPS3

Correlation between AD stages and RNA editing frequency

Tissue	ADeditomID	position	P-val	Coeff.
CER	ADediting_282544	chr11_75408248_+	0.000474722535409622	0.330610080862557
CER	ADediting_282547	chr11_75408274_+	0.000953588666929154	0.313508771224341
CER	ADediting_282550	chr11_75408636_+	0.00149459915178744	0.301933164148091
CER	ADediting_282554	chr11_75409042_+	0.000111986514097549	0.363171826877088

Correlation between AD stages and this gene's expression

Tissue

P-val

Coeff.

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RelatedDrugs for RPS3

Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for RPS3

Diseases associated with this gene.
(DisGeNet 4.0)

Gene	Disease ID	Disease name	# pubmeds	Source
RPS3	C0025202	melanoma	1	CTD_human
RPS3	C1257806	Chromosomal Instability	1	CTD_human

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Gene summary for RPS3

RNA A-to-I events for RPS3

RNA editing positional annotations for RPS3 using Annovar

RNA A-to-I editing events in the alternative splicing sites for RPS3

Differntial gene expression between RNA A-to-I edited versus non-edited samples for RPS3

Protein coding region RNA A-to-I editings for RPS3

The effects of the RNA editing to the miRNA binding sites for RPS3

The effects of the RNA editing to the stability of the RNA structures for RPS3

Relation with ADAR for RPS3

Relation with AD stages for RPS3

RelatedDrugs for RPS3

RelatedDiseases for RPS3

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited versus non-edited samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with AD stages
	Related drugs with this gene
	Related diseases with this gene