|
||||||
|
 | |
| |
| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
| |
| |
| The effects of the RNA editing to the stability of the RNA structures |
| |
| |
| |
|
Gene summary for RPL28 |
 Gene summary |
| Gene information | Gene symbol | RPL28 | Gene ID | 6158 |
| Gene name | ribosomal protein L28 | |
| Synonyms | L28 | |
| Cytomap | 19q13.42 | |
| Type of gene | protein-coding | |
| Description | 60S ribosomal protein L28large ribosomal subunit protein eL28 | |
| Modification date | 20200313 | |
| UniProtAcc | P46779, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
RNA A-to-I events for RPL28 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_782980(55389027, +), ADediting_782981(55389165, +), ADediting_782982(55389174, +), ADediting_782983(55389175, +), ADediting_782984(55389275, +), ADediting_782985(55389280, +), ADediting_782986(55389284, +), ADediting_782987(55389285, +), ADediting_782988(55389287, +), ADediting_782989(55389324, +), ADediting_782990(55390261, +), ADediting_782991(55390284, +), ADediting_782992(55390305, +), ADediting_782993(55390346, +), ADediting_782994(55390360, +), ADediting_782995(55390405, +), ADediting_782996(55390414, +), ADediting_782997(55391478, +), ADediting_782998(55393694, +), ADediting_782999(55393718, +), ADediting_783000(55393735, +), ADediting_783001(55393748, +), ADediting_783002(55393749, +), ADediting_783003(55394034, +), ADediting_783004(55394045, +), ADediting_783005(55394051, +), ADediting_783006(55394075, +), ADediting_783007(55394079, +), ADediting_783008(55394085, +), ADediting_783009(55394119, +), ADediting_783010(55394141, +), ADediting_783011(55394147, +), ADediting_783012(55394164, +), ADediting_783013(55394168, +), ADediting_783014(55394200, +), ADediting_783015(55394211, +), ADediting_783016(55394363, +), ADediting_783017(55394372, +), ADediting_783018(55394389, +), ADediting_783019(55394399, +), ADediting_783020(55395583, +), ADediting_783021(55395585, +), ADediting_783022(55396124, +), ADediting_783023(55396137, +), ADediting_783024(55396144, +), ADediting_783025(55396150, +), ADediting_783026(55396156, +), ADediting_783027(55396186, +), ADediting_783028(55396196, +), ADediting_783029(55396206, +), ADediting_783030(55396787, +), ADediting_783031(55396960, +), ADediting_783032(55396997, +), ADediting_783033(55397460, +), ADediting_783034(55398009, +), ADediting_783035(55398010, +), ADediting_783036(55398075, +), ADediting_783037(55398076, +), ADediting_1559121(55389272, +), ADediting_1559122(55390331, +), ADediting_1559123(55393911, +), ADediting_1559124(55394212, +), ADediting_1559125(55394603, +), ADediting_1559126(55395214, +), ADediting_1559127(55395717, +), ADediting_1559128(55396928, +), ADediting_1559129(55398874, +), ADediting_1631695(55394244, +), |
Top |
RNA editing positional annotations for RPL28 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_782980 | chr19_55389027_+ | UTR3 |
| ADediting_782981 | chr19_55389165_+ | UTR3 |
| ADediting_782982 | chr19_55389174_+ | UTR3 |
| ADediting_782983 | chr19_55389175_+ | UTR3 |
| ADediting_782984 | chr19_55389275_+ | UTR3 |
| ADediting_782985 | chr19_55389280_+ | UTR3 |
| ADediting_782986 | chr19_55389284_+ | UTR3 |
| ADediting_782987 | chr19_55389285_+ | UTR3 |
| ADediting_782988 | chr19_55389287_+ | UTR3 |
| ADediting_782989 | chr19_55389324_+ | UTR3 |
| ADediting_782990 | chr19_55390261_+ | UTR3 |
| ADediting_782991 | chr19_55390284_+ | UTR3 |
| ADediting_782992 | chr19_55390305_+ | UTR3 |
| ADediting_782993 | chr19_55390346_+ | UTR3 |
| ADediting_782994 | chr19_55390360_+ | UTR3 |
| ADediting_782995 | chr19_55390405_+ | UTR3 |
| ADediting_782996 | chr19_55390414_+ | UTR3 |
| ADediting_782997 | chr19_55391478_+ | UTR3 |
| ADediting_782998 | chr19_55393694_+ | intronic |
| ADediting_782999 | chr19_55393718_+ | intronic |
| ADediting_783000 | chr19_55393735_+ | intronic |
| ADediting_783001 | chr19_55393748_+ | intronic |
| ADediting_783002 | chr19_55393749_+ | intronic |
| ADediting_783003 | chr19_55394034_+ | intronic |
| ADediting_783004 | chr19_55394045_+ | intronic |
| ADediting_783005 | chr19_55394051_+ | intronic |
| ADediting_783006 | chr19_55394075_+ | intronic |
| ADediting_783007 | chr19_55394079_+ | intronic |
| ADediting_783008 | chr19_55394085_+ | intronic |
| ADediting_783009 | chr19_55394119_+ | intronic |
| ADediting_783010 | chr19_55394141_+ | intronic |
| ADediting_783011 | chr19_55394147_+ | intronic |
| ADediting_783012 | chr19_55394164_+ | intronic |
| ADediting_783013 | chr19_55394168_+ | intronic |
| ADediting_783014 | chr19_55394200_+ | intronic |
| ADediting_783015 | chr19_55394211_+ | intronic |
| ADediting_783016 | chr19_55394363_+ | intronic |
| ADediting_783017 | chr19_55394372_+ | intronic |
| ADediting_783018 | chr19_55394389_+ | intronic |
| ADediting_783019 | chr19_55394399_+ | intronic |
| ADediting_783020 | chr19_55395583_+ | intronic |
| ADediting_783021 | chr19_55395585_+ | intronic |
| ADediting_783022 | chr19_55396124_+ | intronic |
| ADediting_783023 | chr19_55396137_+ | intronic |
| ADediting_783024 | chr19_55396144_+ | intronic |
| ADediting_783025 | chr19_55396150_+ | intronic |
| ADediting_783026 | chr19_55396156_+ | intronic |
| ADediting_783027 | chr19_55396186_+ | intronic |
| ADediting_783028 | chr19_55396196_+ | intronic |
| ADediting_783029 | chr19_55396206_+ | intronic |
| ADediting_783030 | chr19_55396787_+ | intronic |
| ADediting_783031 | chr19_55396960_+ | intronic |
| ADediting_783032 | chr19_55396997_+ | intronic |
| ADediting_783033 | chr19_55397460_+ | intronic |
| ADediting_783034 | chr19_55398009_+ | intronic |
| ADediting_783035 | chr19_55398010_+ | intronic |
| ADediting_783036 | chr19_55398075_+ | intronic |
| ADediting_783037 | chr19_55398076_+ | intronic |
| ADediting_1559121 | chr19_55389272_+ | UTR3 |
| ADediting_1559122 | chr19_55390331_+ | UTR3 |
| ADediting_1559123 | chr19_55393911_+ | intronic |
| ADediting_1559124 | chr19_55394212_+ | intronic |
| ADediting_1559125 | chr19_55394603_+ | intronic |
| ADediting_1559126 | chr19_55395214_+ | intronic |
| ADediting_1559127 | chr19_55395717_+ | intronic |
| ADediting_1559128 | chr19_55396928_+ | intronic |
| ADediting_1559129 | chr19_55398874_+ | intronic |
| ADediting_1631695 | chr19_55394244_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_782981 | chr19_55389165_+ | SINE | Alu | Name=AluJr |
| ADediting_782982 | chr19_55389174_+ | SINE | Alu | Name=AluJr |
| ADediting_782983 | chr19_55389175_+ | SINE | Alu | Name=AluJr |
| ADediting_782984 | chr19_55389275_+ | SINE | Alu | Name=AluJr |
| ADediting_782985 | chr19_55389280_+ | SINE | Alu | Name=AluJr |
| ADediting_782986 | chr19_55389284_+ | SINE | Alu | Name=AluJr |
| ADediting_782987 | chr19_55389285_+ | SINE | Alu | Name=AluJr |
| ADediting_782988 | chr19_55389287_+ | SINE | Alu | Name=AluJr |
| ADediting_782989 | chr19_55389324_+ | SINE | Alu | Name=AluJr |
| ADediting_782990 | chr19_55390261_+ | SINE | Alu | Name=AluSz |
| ADediting_782991 | chr19_55390284_+ | SINE | Alu | Name=AluSz |
| ADediting_782992 | chr19_55390305_+ | SINE | Alu | Name=AluSz |
| ADediting_782993 | chr19_55390346_+ | SINE | Alu | Name=AluSz |
| ADediting_782994 | chr19_55390360_+ | SINE | Alu | Name=AluSz |
| ADediting_782995 | chr19_55390405_+ | SINE | Alu | Name=AluSz |
| ADediting_782996 | chr19_55390414_+ | SINE | Alu | Name=AluSz |
| ADediting_782998 | chr19_55393694_+ | SINE | Alu | Name=AluSx1 |
| ADediting_782999 | chr19_55393718_+ | SINE | Alu | Name=AluSx1 |
| ADediting_783000 | chr19_55393735_+ | SINE | Alu | Name=AluSx1 |
| ADediting_783001 | chr19_55393748_+ | SINE | Alu | Name=AluSx1 |
| ADediting_783002 | chr19_55393749_+ | SINE | Alu | Name=AluSx1 |
| ADediting_783003 | chr19_55394034_+ | SINE | Alu | Name=AluSc8 |
| ADediting_783004 | chr19_55394045_+ | SINE | Alu | Name=AluSc8 |
| ADediting_783005 | chr19_55394051_+ | SINE | Alu | Name=AluSc8 |
| ADediting_783006 | chr19_55394075_+ | SINE | Alu | Name=AluSc8 |
| ADediting_783007 | chr19_55394079_+ | SINE | Alu | Name=AluSc8 |
| ADediting_783008 | chr19_55394085_+ | SINE | Alu | Name=AluSc8 |
| ADediting_783009 | chr19_55394119_+ | SINE | Alu | Name=AluSc8 |
| ADediting_783010 | chr19_55394141_+ | SINE | Alu | Name=AluSc8 |
| ADediting_783011 | chr19_55394147_+ | SINE | Alu | Name=AluSc8 |
| ADediting_783012 | chr19_55394164_+ | SINE | Alu | Name=AluSc8 |
| ADediting_783013 | chr19_55394168_+ | SINE | Alu | Name=AluSc8 |
| ADediting_783014 | chr19_55394200_+ | SINE | Alu | Name=AluSc8 |
| ADediting_783015 | chr19_55394211_+ | SINE | Alu | Name=AluSc8 |
| ADediting_783016 | chr19_55394363_+ | SINE | Alu | Name=AluJr |
| ADediting_783017 | chr19_55394372_+ | SINE | Alu | Name=AluJr |
| ADediting_783018 | chr19_55394389_+ | SINE | Alu | Name=AluJr |
| ADediting_783019 | chr19_55394399_+ | SINE | Alu | Name=AluJr |
| ADediting_783020 | chr19_55395583_+ | SINE | Alu | Name=AluY |
| ADediting_783021 | chr19_55395585_+ | SINE | Alu | Name=AluY |
| ADediting_783022 | chr19_55396124_+ | SINE | Alu | Name=AluJo |
| ADediting_783023 | chr19_55396137_+ | SINE | Alu | Name=AluJo |
| ADediting_783024 | chr19_55396144_+ | SINE | Alu | Name=AluJo |
| ADediting_783025 | chr19_55396150_+ | SINE | Alu | Name=AluJo |
| ADediting_783026 | chr19_55396156_+ | SINE | Alu | Name=AluJo |
| ADediting_783027 | chr19_55396186_+ | SINE | Alu | Name=AluJo |
| ADediting_783028 | chr19_55396196_+ | SINE | Alu | Name=AluJo |
| ADediting_783029 | chr19_55396206_+ | SINE | Alu | Name=AluJo |
| ADediting_783030 | chr19_55396787_+ | SINE | Alu | Name=AluY |
| ADediting_783031 | chr19_55396960_+ | SINE | Alu | Name=AluJb |
| ADediting_783032 | chr19_55396997_+ | SINE | Alu | Name=AluJb |
| ADediting_783033 | chr19_55397460_+ | SINE | Alu | Name=AluY |
| ADediting_783034 | chr19_55398009_+ | SINE | Alu | Name=AluSz6 |
| ADediting_783035 | chr19_55398010_+ | SINE | Alu | Name=AluSz6 |
| ADediting_783036 | chr19_55398075_+ | SINE | Alu | Name=AluSz6 |
| ADediting_783037 | chr19_55398076_+ | SINE | Alu | Name=AluSz6 |
| ADediting_1559121 | chr19_55389272_+ | SINE | Alu | Name=AluJr |
| ADediting_1559122 | chr19_55390331_+ | SINE | Alu | Name=AluSz |
| ADediting_1559123 | chr19_55393911_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1559124 | chr19_55394212_+ | SINE | Alu | Name=AluSc8 |
| ADediting_1559125 | chr19_55394603_+ | SINE | Alu | Name=AluJr |
| ADediting_1559126 | chr19_55395214_+ | SINE | Alu | Name=AluSz |
| ADediting_1559127 | chr19_55395717_+ | SINE | Alu | Name=AluY |
| ADediting_1559128 | chr19_55396928_+ | SINE | Alu | Name=AluJb |
| ADediting_1559129 | chr19_55398874_+ | SINE | Alu | Name=AluSz |
| ADediting_1631695 | chr19_55394244_+ | SINE | Alu | Name=AluSc8 |
Top |
RNA A-to-I editing events in the alternative splicing sites for RPL28 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for RPL28 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
 | |
 | |
 | |
 | |
 | |
 | |
| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
 |
 |
 |
 |
 |
| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for RPL28 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for RPL28 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1559121 | chr19_55389272_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-371b-3p | chr19 | 55389270 | 55389276 | 7mer-m8 | 55389255 | 55389277 | 154 | -23.02 |
| ADediting_1559122 | chr19_55390331_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-1247-3p | chr19 | 55390325 | 55390331 | 7mer-m8 | 55390310 | 55390332 | 160 | -27.57 |
| ADediting_782981 | chr19_55389165_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-6840-3p | chr19 | 55389160 | 55389166 | 7mer-m8 | 55389146 | 55389167 | 140 | -19.22 |
| ADediting_782982 | chr19_55389174_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-96-3p | chr19 | 55389169 | 55389175 | 7mer-m8 | 55389154 | 55389176 | 141 | -12.18 |
| ADediting_782984 | chr19_55389275_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-518e-3p | chr19 | 55389271 | 55389277 | 7mer-m8 | 55389258 | 55389278 | 154 | -19.64 |
| ADediting_782985 | chr19_55389280_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-3136-3p | chr19 | 55389276 | 55389283 | 8mer-1a | 55389263 | 55389283 | 149 | -18.53 |
| ADediting_782985 | chr19_55389280_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-7155-3p | chr19 | 55389276 | 55389283 | 8mer-1a | 55389265 | 55389283 | 156 | -21.85 |
| ADediting_782986 | chr19_55389284_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-3615 | chr19 | 55389281 | 55389287 | 7mer-m8 | 55389268 | 55389288 | 155 | -27.17 |
| ADediting_782986 | chr19_55389284_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-4638-5p | chr19 | 55389279 | 55389286 | 8mer-1a | 55389266 | 55389286 | 150 | -18.86 |
| ADediting_782989 | chr19_55389324_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-143-5p | chr19 | 55389320 | 55389326 | 7mer-m8 | 55389305 | 55389327 | 159 | -23.53 |
| ADediting_782990 | chr19_55390261_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-324-3p | chr19 | 55390257 | 55390263 | 7mer-m8 | 55390242 | 55390264 | 142 | -21.82 |
| ADediting_782990 | chr19_55390261_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-4252 | chr19 | 55390258 | 55390264 | 7mer-m8 | 55390246 | 55390265 | 147 | -23.02 |
| ADediting_782990 | chr19_55390261_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-4793-3p | chr19 | 55390254 | 55390260 | 7mer-m8 | 55390237 | 55390261 | 151 | -21.69 |
| ADediting_782991 | chr19_55390284_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-6089 | chr19 | 55390282 | 55390288 | 7mer-m8 | 55390266 | 55390289 | 169 | -39.07 |
| ADediting_782992 | chr19_55390305_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-6078 | chr19 | 55390301 | 55390308 | 8mer-1a | 55390289 | 55390308 | 148 | -20.43 |
| ADediting_782993 | chr19_55390346_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-100-5p | chr19 | 55390342 | 55390348 | 7mer-m8 | 55390329 | 55390349 | 160 | -20.88 |
| ADediting_782993 | chr19_55390346_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-99a-5p | chr19 | 55390342 | 55390348 | 7mer-m8 | 55390329 | 55390349 | 160 | -19.76 |
| ADediting_782993 | chr19_55390346_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-99b-5p | chr19 | 55390342 | 55390348 | 7mer-m8 | 55390329 | 55390349 | 152 | -24.4 |
| ADediting_782994 | chr19_55390360_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-4466 | chr19 | 55390357 | 55390363 | 7mer-m8 | 55390346 | 55390364 | 141 | -23.29 |
| ADediting_782994 | chr19_55390360_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-675-5p | chr19 | 55390357 | 55390363 | 7mer-m8 | 55390343 | 55390364 | 161 | -27.69 |
| ADediting_782995 | chr19_55390405_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-433-5p | chr19 | 55390399 | 55390405 | 7mer-m8 | 55390383 | 55390406 | 153 | -19.67 |
| ADediting_782995 | chr19_55390405_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-553 | chr19 | 55390401 | 55390407 | 7mer-m8 | 55390388 | 55390408 | 167 | -23.44 |
| ADediting_782996 | chr19_55390414_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-3940-3p | chr19 | 55390411 | 55390417 | 7mer-m8 | 55390397 | 55390418 | 140 | -18.92 |
| ADediting_782997 | chr19_55391478_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-3189-3p | chr19 | 55391472 | 55391478 | 7mer-m8 | 55391459 | 55391479 | 152 | -21.7 |
| ADediting_782997 | chr19_55391478_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-635 | chr19 | 55391471 | 55391477 | 7mer-m8 | 55391456 | 55391478 | 140 | -14.93 |
| ADediting_782997 | chr19_55391478_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-6774-5p | chr19 | 55391471 | 55391477 | 7mer-m8 | 55391455 | 55391478 | 145 | -18.48 |
| ADediting_782997 | chr19_55391478_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-6813-3p | chr19 | 55391473 | 55391479 | 7mer-m8 | 55391460 | 55391480 | 142 | -14.48 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1559121 | chr19_55389272_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-572 | chr19 | 55389265 | 55389271 | 7mer-m8 | 55389254 | 55389272 | 148 | -22.82 |
| ADediting_782981 | chr19_55389165_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-3135a | chr19 | 55389161 | 55389168 | 8mer-1a | 55389149 | 55389168 | 152 | -18.69 |
| ADediting_782981 | chr19_55389165_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-4774-3p | chr19 | 55389163 | 55389169 | 7mer-m8 | 55389149 | 55389170 | 150 | -13.72 |
| ADediting_782984 | chr19_55389275_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-302e | chr19 | 55389271 | 55389277 | 7mer-m8 | 55389262 | 55389278 | 146 | -15.66 |
| ADediting_782984 | chr19_55389275_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-373-3p | chr19 | 55389271 | 55389277 | 7mer-m8 | 55389256 | 55389278 | 154 | -19.03 |
| ADediting_782984 | chr19_55389275_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-520a-3p | chr19 | 55389271 | 55389277 | 7mer-m8 | 55389257 | 55389278 | 154 | -15.14 |
| ADediting_782984 | chr19_55389275_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-520b-3p | chr19 | 55389271 | 55389277 | 7mer-m8 | 55389258 | 55389278 | 150 | -15.59 |
| ADediting_782984 | chr19_55389275_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-520c-3p | chr19 | 55389271 | 55389277 | 7mer-m8 | 55389257 | 55389278 | 150 | -17.44 |
| ADediting_782984 | chr19_55389275_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-520d-3p | chr19 | 55389271 | 55389277 | 7mer-m8 | 55389257 | 55389278 | 154 | -15.47 |
| ADediting_782984 | chr19_55389275_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-520e-3p | chr19 | 55389271 | 55389277 | 7mer-m8 | 55389256 | 55389278 | 153 | -18.13 |
| ADediting_782989 | chr19_55389324_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-4280 | chr19 | 55389321 | 55389327 | 7mer-m8 | 55389308 | 55389328 | 151 | -16.93 |
| ADediting_782989 | chr19_55389324_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-4460 | chr19 | 55389317 | 55389323 | 7mer-m8 | 55389303 | 55389324 | 144 | -9.81 |
| ADediting_782990 | chr19_55390261_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-32-5p | chr19 | 55390255 | 55390261 | 7mer-m8 | 55390242 | 55390262 | 150 | -13.87 |
| ADediting_782990 | chr19_55390261_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-363-3p | chr19 | 55390255 | 55390261 | 7mer-m8 | 55390242 | 55390262 | 148 | -16.01 |
| ADediting_782990 | chr19_55390261_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-367-3p | chr19 | 55390255 | 55390261 | 7mer-m8 | 55390240 | 55390262 | 152 | -18.47 |
| ADediting_782991 | chr19_55390284_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-17-3p | chr19 | 55390278 | 55390284 | 7mer-m8 | 55390265 | 55390285 | 153 | -18.99 |
| ADediting_782991 | chr19_55390284_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-485-5p | chr19 | 55390282 | 55390288 | 7mer-m8 | 55390269 | 55390289 | 153 | -17.86 |
| ADediting_782991 | chr19_55390284_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-6884-5p | chr19 | 55390282 | 55390288 | 7mer-m8 | 55390267 | 55390289 | 146 | -20.16 |
| ADediting_782994 | chr19_55390360_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-4455 | chr19 | 55390358 | 55390365 | 8mer-1a | 55390350 | 55390365 | 146 | -17.17 |
| ADediting_782995 | chr19_55390405_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-224-3p | chr19 | 55390401 | 55390407 | 7mer-m8 | 55390383 | 55390408 | 149 | -18.68 |
| ADediting_782995 | chr19_55390405_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-4698 | chr19 | 55390403 | 55390409 | 7mer-m8 | 55390390 | 55390410 | 149 | -18.72 |
| ADediting_782995 | chr19_55390405_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-522-3p | chr19 | 55390401 | 55390407 | 7mer-m8 | 55390387 | 55390408 | 140 | -13.98 |
| ADediting_782996 | chr19_55390414_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-3187-5p | chr19 | 55390408 | 55390414 | 7mer-m8 | 55390396 | 55390415 | 152 | -28.58 |
| ADediting_782996 | chr19_55390414_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-5189-5p | chr19 | 55390408 | 55390414 | 7mer-m8 | 55390394 | 55390415 | 152 | -22.11 |
| ADediting_782996 | chr19_55390414_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-661 | chr19 | 55390410 | 55390416 | 7mer-m8 | 55390394 | 55390417 | 141 | -19.17 |
| ADediting_782996 | chr19_55390414_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-939-3p | chr19 | 55390409 | 55390415 | 7mer-m8 | 55390396 | 55390416 | 140 | -15.63 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-5688 | chr19 | 55390091 | 55390097 | 7mer-m8 | 55390081 | 55390098 | 146 | -14.04 |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-5688 | chr19 | 55390117 | 55390123 | 7mer-m8 | 55390102 | 55390124 | 155 | -19.69 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-4477b | chr19 | 55391616 | 55391622 | 7mer-m8 | 55391603 | 55391623 | 153 | -13.82 |
| ADediting_496066 | chr15_66496985_- | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-4512 | chr19 | 55390570 | 55390577 | 8mer-1a | 55390555 | 55390577 | 143 | -21.51 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-4775 | chr19 | 55392066 | 55392072 | 7mer-m8 | 55392054 | 55392073 | 149 | -9.67 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000108107.14 | ENST00000560055.5 | RPL28-209 | hsa-miR-4775 | chr19 | 55403177 | 55403183 | 7mer-m8 | 55403163 | 55403184 | 145 | -11.56 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-5585-3p | chr19 | 55391675 | 55391681 | 7mer-m8 | 55391661 | 55391682 | 161 | -24.69 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-5585-3p | chr19 | 55388645 | 55388651 | 7mer-m8 | 55388631 | 55388652 | 150 | -19.53 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000108107.14 | ENST00000560583.5 | RPL28-210 | hsa-miR-5585-3p | chr19 | 55388645 | 55388651 | 7mer-m8 | 55388631 | 55388652 | 150 | -19.53 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-4477b | chr19 | 55390528 | 55390534 | 7mer-m8 | 55390510 | 55390535 | 152 | -13.78 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-4477b | chr19 | 55390528 | 55390534 | 7mer-m8 | 55390510 | 55390535 | 152 | -13.78 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-641 | chr19 | 55391800 | 55391806 | 7mer-m8 | 55391780 | 55391807 | 151 | -18.59 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-641 | chr19 | 55391800 | 55391806 | 7mer-m8 | 55391780 | 55391807 | 151 | -18.59 |
| ADediting_291761 | chr11_93733708_- | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-1304-3p | chr19 | 55389353 | 55389359 | 7mer-m8 | 55389340 | 55389360 | 146 | -16.22 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-4775 | chr19 | 55389195 | 55389201 | 7mer-m8 | 55389181 | 55389202 | 151 | -8.85 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000108107.14 | ENST00000344063.6 | RPL28-201 | hsa-miR-4775 | chr19 | 55391749 | 55391755 | 7mer-1a | 55391734 | 55391755 | 140 | -11.57 |
| Differentially expressed gene-miRNA network |
Top |
The effects of the RNA editing to the stability of the RNA structures for RPL28 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000344063.6 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_782980 | ENST00000344063.6 | chr19_55389027_+ | 1738 | -1904.40 | -1901.40 | -1945.00 |
| ADediting_782981 | ENST00000344063.6 | chr19_55389165_+ | 1876 | -1908.00 | -1901.40 | -1945.00 |
| ADediting_782982 | ENST00000344063.6 | chr19_55389174_+ | 1885 | -1904.80 | -1901.40 | -1945.00 |
| ADediting_782983 | ENST00000344063.6 | chr19_55389175_+ | 1886 | -1904.90 | -1901.40 | -1945.00 |
| ADediting_1559121 | ENST00000344063.6 | chr19_55389272_+ | 1983 | -1900.40 | -1901.40 | -1945.00 |
| ADediting_782984 | ENST00000344063.6 | chr19_55389275_+ | 1986 | -1906.80 | -1901.40 | -1945.00 |
| ADediting_782985 | ENST00000344063.6 | chr19_55389280_+ | 1991 | -1900.40 | -1901.40 | -1945.00 |
| ADediting_782986 | ENST00000344063.6 | chr19_55389284_+ | 1995 | -1903.20 | -1901.40 | -1945.00 |
| ADediting_782987 | ENST00000344063.6 | chr19_55389285_+ | 1996 | -1907.20 | -1901.40 | -1945.00 |
| ADediting_782988 | ENST00000344063.6 | chr19_55389287_+ | 1998 | -1903.30 | -1901.40 | -1945.00 |
| ADediting_782989 | ENST00000344063.6 | chr19_55389324_+ | 2035 | -1906.30 | -1901.40 | -1945.00 |
| ADediting_782990 | ENST00000344063.6 | chr19_55390261_+ | 2972 | -1905.80 | -1901.40 | -1945.00 |
| ADediting_782991 | ENST00000344063.6 | chr19_55390284_+ | 2995 | -1900.70 | -1901.40 | -1945.00 |
| ADediting_782992 | ENST00000344063.6 | chr19_55390305_+ | 3016 | -1901.10 | -1901.40 | -1945.00 |
| ADediting_1559122 | ENST00000344063.6 | chr19_55390331_+ | 3042 | -1901.20 | -1901.40 | -1945.00 |
| ADediting_782993 | ENST00000344063.6 | chr19_55390346_+ | 3057 | -1900.70 | -1901.40 | -1945.00 |
| ADediting_782994 | ENST00000344063.6 | chr19_55390360_+ | 3071 | -1901.00 | -1901.40 | -1945.00 |
| ADediting_782995 | ENST00000344063.6 | chr19_55390405_+ | 3116 | -1901.70 | -1901.40 | -1945.00 |
| ADediting_782996 | ENST00000344063.6 | chr19_55390414_+ | 3125 | -1901.40 | -1901.40 | -1945.00 |
| ADediting_782997 | ENST00000344063.6 | chr19_55391478_+ | 4189 | -1908.00 | -1901.40 | -1945.00 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
Top |
Relation with ADAR for RPL28 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_782981 | chr19_55389165_+ | 0.000676954445683067 | 0.274453942744025 | 0.000186261786556098 | 0.300550109246836 | 0.273316493730955 | 0.0900149897396831 |
| CER | ADediting_782982 | chr19_55389174_+ | 0.00149208826363945 | 0.257113795959221 | 7.82678258036625e-05 | 0.316791042461464 | 0.000246709344731038 | 0.295075319335643 |
| CER | ADediting_782983 | chr19_55389175_+ | 2.63241254261742e-05 | 0.335965857320406 | 3.91515713205544e-09 | 0.457637031514988 | 0.113553282652543 | 0.129742840237979 |
| CER | ADediting_782984 | chr19_55389275_+ | 0.000614702372319084 | 0.276494378824781 | 7.06235679399735e-09 | 0.450839166580632 | 0.28320321940252 | 0.0881893354613686 |
| CER | ADediting_782985 | chr19_55389280_+ | 4.10275860332755e-05 | 0.328310946899828 | 1.74439072325808e-09 | 0.466717871862836 | 0.358802737339732 | 0.0754500210714415 |
| CER | ADediting_782987 | chr19_55389285_+ | 2.16873885400093e-06 | 0.375657549800713 | 6.62854068955728e-13 | 0.543518119911651 | 0.172476195001401 | 0.111979920770059 |
| CER | ADediting_782996 | chr19_55390414_+ | 0.0102800629802456 | 0.208964121892481 | 0.00015186968865778 | 0.304459617424851 | 0.00396914261879525 | 0.233885650689649 |
| CER | ADediting_783017 | chr19_55394372_+ | 0.00316107389007306 | 0.239485370725755 | 2.33325970857324e-07 | 0.407148088472113 | 0.0422867900227383 | 0.166041115251749 |
| CER | ADediting_783018 | chr19_55394389_+ | 0.0166399459949749 | 0.195263288865849 | 3.52806318458273e-06 | 0.36832570056129 | 0.178922522677669 | 0.110331287702443 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 8.25085263972468e-09 | 0.319977596326783 | 6.17938739468775e-21 | 0.499140388754435 | 0.168974720175286 | 0.0783198176266333 |
| AC | 2.89212736613742e-47 | 0.754529056569363 | 1.42062873806397e-30 | 0.64309322434149 | 5.44856549741122e-22 | 0.55945412860927 |
| PCC | 4.73767085522255e-08 | 0.38251578984292 | 1.69223119893549e-07 | 0.367534870725205 | 0.00538594963062864 | 0.200635793726752 |
| CER | 7.0255288544584e-09 | -0.450900072287827 | 2.83903211994756e-10 | -0.486192074513341 | 0.0371188275273193 | -0.170373876587107 |
| TCX | 0.000716106843531658 | -0.273257406920415 | 4.32207829670276e-08 | -0.428981834617084 | 0.000733736523348199 | 0.272738162243035 |
| FP | 2.73042876207291e-08 | 0.401728649944319 | 0.369424299466067 | 0.0676740041154295 | 0.0179502105827628 | 0.177229473500242 |
| IFG | 2.62830051453584e-05 | 0.737167104225167 | 0.00241893292071046 | 0.579109251663657 | 0.0360539985425616 | 0.421100380971772 |
| STG | 0.00434842965291132 | 0.308154832024005 | 0.265956516670799 | -0.122754880824254 | 0.373168893652184 | 0.0984057008043478 |
Top |
Relation with AD stages for RPL28 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_782982 | chr19_55389174_+ | 1.17797660646762e-05 | 0.40788155598143 |
| CER | ADediting_782983 | chr19_55389175_+ | 0.000513358622743585 | 0.32874053012873 |
| CER | ADediting_782984 | chr19_55389275_+ | 0.000444950371126396 | 0.332148736332518 |
| CER | ADediting_782987 | chr19_55389285_+ | 2.81223135661001e-05 | 0.391363388141303 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 1.9265935982714e-07 | -0.475972695261134 |
Top |
RelatedDrugs for RPL28 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for RPL28 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| RPL28 | C0043094 | Weight Gain | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|