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Center for Computational Systems Medicine
Soverview

Gene summary

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RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

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Protein coding region RNA A-to-I editings

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The effects of the RNA editing to the miRNA binding sites

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The effects of the RNA editing to the stability of the RNA structures

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Relation with ADAR

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Relation with AD stages

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Related drugs with this gene

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Related diseases with this gene


Gene summary for RPL28

check button Gene summary
Gene informationGene symbol

RPL28

Gene ID

6158

Gene nameribosomal protein L28
SynonymsL28
Cytomap

19q13.42

Type of geneprotein-coding
Description60S ribosomal protein L28large ribosomal subunit protein eL28
Modification date20200313
UniProtAcc

P46779,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for RPL28

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_782980(55389027, +), ADediting_782981(55389165, +), ADediting_782982(55389174, +), ADediting_782983(55389175, +), ADediting_782984(55389275, +), ADediting_782985(55389280, +), ADediting_782986(55389284, +), ADediting_782987(55389285, +), ADediting_782988(55389287, +), ADediting_782989(55389324, +), ADediting_782990(55390261, +), ADediting_782991(55390284, +), ADediting_782992(55390305, +), ADediting_782993(55390346, +), ADediting_782994(55390360, +), ADediting_782995(55390405, +), ADediting_782996(55390414, +), ADediting_782997(55391478, +), ADediting_782998(55393694, +), ADediting_782999(55393718, +), ADediting_783000(55393735, +), ADediting_783001(55393748, +), ADediting_783002(55393749, +), ADediting_783003(55394034, +), ADediting_783004(55394045, +), ADediting_783005(55394051, +), ADediting_783006(55394075, +), ADediting_783007(55394079, +), ADediting_783008(55394085, +), ADediting_783009(55394119, +), ADediting_783010(55394141, +), ADediting_783011(55394147, +), ADediting_783012(55394164, +), ADediting_783013(55394168, +), ADediting_783014(55394200, +), ADediting_783015(55394211, +), ADediting_783016(55394363, +), ADediting_783017(55394372, +), ADediting_783018(55394389, +), ADediting_783019(55394399, +), ADediting_783020(55395583, +), ADediting_783021(55395585, +), ADediting_783022(55396124, +), ADediting_783023(55396137, +), ADediting_783024(55396144, +), ADediting_783025(55396150, +), ADediting_783026(55396156, +), ADediting_783027(55396186, +), ADediting_783028(55396196, +), ADediting_783029(55396206, +), ADediting_783030(55396787, +), ADediting_783031(55396960, +), ADediting_783032(55396997, +), ADediting_783033(55397460, +), ADediting_783034(55398009, +), ADediting_783035(55398010, +), ADediting_783036(55398075, +), ADediting_783037(55398076, +), ADediting_1559121(55389272, +), ADediting_1559122(55390331, +), ADediting_1559123(55393911, +), ADediting_1559124(55394212, +), ADediting_1559125(55394603, +), ADediting_1559126(55395214, +), ADediting_1559127(55395717, +), ADediting_1559128(55396928, +), ADediting_1559129(55398874, +), ADediting_1631695(55394244, +),

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RNA editing positional annotations for RPL28 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_782980chr19_55389027_+UTR3
ADediting_782981chr19_55389165_+UTR3
ADediting_782982chr19_55389174_+UTR3
ADediting_782983chr19_55389175_+UTR3
ADediting_782984chr19_55389275_+UTR3
ADediting_782985chr19_55389280_+UTR3
ADediting_782986chr19_55389284_+UTR3
ADediting_782987chr19_55389285_+UTR3
ADediting_782988chr19_55389287_+UTR3
ADediting_782989chr19_55389324_+UTR3
ADediting_782990chr19_55390261_+UTR3
ADediting_782991chr19_55390284_+UTR3
ADediting_782992chr19_55390305_+UTR3
ADediting_782993chr19_55390346_+UTR3
ADediting_782994chr19_55390360_+UTR3
ADediting_782995chr19_55390405_+UTR3
ADediting_782996chr19_55390414_+UTR3
ADediting_782997chr19_55391478_+UTR3
ADediting_782998chr19_55393694_+intronic
ADediting_782999chr19_55393718_+intronic
ADediting_783000chr19_55393735_+intronic
ADediting_783001chr19_55393748_+intronic
ADediting_783002chr19_55393749_+intronic
ADediting_783003chr19_55394034_+intronic
ADediting_783004chr19_55394045_+intronic
ADediting_783005chr19_55394051_+intronic
ADediting_783006chr19_55394075_+intronic
ADediting_783007chr19_55394079_+intronic
ADediting_783008chr19_55394085_+intronic
ADediting_783009chr19_55394119_+intronic
ADediting_783010chr19_55394141_+intronic
ADediting_783011chr19_55394147_+intronic
ADediting_783012chr19_55394164_+intronic
ADediting_783013chr19_55394168_+intronic
ADediting_783014chr19_55394200_+intronic
ADediting_783015chr19_55394211_+intronic
ADediting_783016chr19_55394363_+intronic
ADediting_783017chr19_55394372_+intronic
ADediting_783018chr19_55394389_+intronic
ADediting_783019chr19_55394399_+intronic
ADediting_783020chr19_55395583_+intronic
ADediting_783021chr19_55395585_+intronic
ADediting_783022chr19_55396124_+intronic
ADediting_783023chr19_55396137_+intronic
ADediting_783024chr19_55396144_+intronic
ADediting_783025chr19_55396150_+intronic
ADediting_783026chr19_55396156_+intronic
ADediting_783027chr19_55396186_+intronic
ADediting_783028chr19_55396196_+intronic
ADediting_783029chr19_55396206_+intronic
ADediting_783030chr19_55396787_+intronic
ADediting_783031chr19_55396960_+intronic
ADediting_783032chr19_55396997_+intronic
ADediting_783033chr19_55397460_+intronic
ADediting_783034chr19_55398009_+intronic
ADediting_783035chr19_55398010_+intronic
ADediting_783036chr19_55398075_+intronic
ADediting_783037chr19_55398076_+intronic
ADediting_1559121chr19_55389272_+UTR3
ADediting_1559122chr19_55390331_+UTR3
ADediting_1559123chr19_55393911_+intronic
ADediting_1559124chr19_55394212_+intronic
ADediting_1559125chr19_55394603_+intronic
ADediting_1559126chr19_55395214_+intronic
ADediting_1559127chr19_55395717_+intronic
ADediting_1559128chr19_55396928_+intronic
ADediting_1559129chr19_55398874_+intronic
ADediting_1631695chr19_55394244_+intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_782981chr19_55389165_+SINEAluName=AluJr
ADediting_782982chr19_55389174_+SINEAluName=AluJr
ADediting_782983chr19_55389175_+SINEAluName=AluJr
ADediting_782984chr19_55389275_+SINEAluName=AluJr
ADediting_782985chr19_55389280_+SINEAluName=AluJr
ADediting_782986chr19_55389284_+SINEAluName=AluJr
ADediting_782987chr19_55389285_+SINEAluName=AluJr
ADediting_782988chr19_55389287_+SINEAluName=AluJr
ADediting_782989chr19_55389324_+SINEAluName=AluJr
ADediting_782990chr19_55390261_+SINEAluName=AluSz
ADediting_782991chr19_55390284_+SINEAluName=AluSz
ADediting_782992chr19_55390305_+SINEAluName=AluSz
ADediting_782993chr19_55390346_+SINEAluName=AluSz
ADediting_782994chr19_55390360_+SINEAluName=AluSz
ADediting_782995chr19_55390405_+SINEAluName=AluSz
ADediting_782996chr19_55390414_+SINEAluName=AluSz
ADediting_782998chr19_55393694_+SINEAluName=AluSx1
ADediting_782999chr19_55393718_+SINEAluName=AluSx1
ADediting_783000chr19_55393735_+SINEAluName=AluSx1
ADediting_783001chr19_55393748_+SINEAluName=AluSx1
ADediting_783002chr19_55393749_+SINEAluName=AluSx1
ADediting_783003chr19_55394034_+SINEAluName=AluSc8
ADediting_783004chr19_55394045_+SINEAluName=AluSc8
ADediting_783005chr19_55394051_+SINEAluName=AluSc8
ADediting_783006chr19_55394075_+SINEAluName=AluSc8
ADediting_783007chr19_55394079_+SINEAluName=AluSc8
ADediting_783008chr19_55394085_+SINEAluName=AluSc8
ADediting_783009chr19_55394119_+SINEAluName=AluSc8
ADediting_783010chr19_55394141_+SINEAluName=AluSc8
ADediting_783011chr19_55394147_+SINEAluName=AluSc8
ADediting_783012chr19_55394164_+SINEAluName=AluSc8
ADediting_783013chr19_55394168_+SINEAluName=AluSc8
ADediting_783014chr19_55394200_+SINEAluName=AluSc8
ADediting_783015chr19_55394211_+SINEAluName=AluSc8
ADediting_783016chr19_55394363_+SINEAluName=AluJr
ADediting_783017chr19_55394372_+SINEAluName=AluJr
ADediting_783018chr19_55394389_+SINEAluName=AluJr
ADediting_783019chr19_55394399_+SINEAluName=AluJr
ADediting_783020chr19_55395583_+SINEAluName=AluY
ADediting_783021chr19_55395585_+SINEAluName=AluY
ADediting_783022chr19_55396124_+SINEAluName=AluJo
ADediting_783023chr19_55396137_+SINEAluName=AluJo
ADediting_783024chr19_55396144_+SINEAluName=AluJo
ADediting_783025chr19_55396150_+SINEAluName=AluJo
ADediting_783026chr19_55396156_+SINEAluName=AluJo
ADediting_783027chr19_55396186_+SINEAluName=AluJo
ADediting_783028chr19_55396196_+SINEAluName=AluJo
ADediting_783029chr19_55396206_+SINEAluName=AluJo
ADediting_783030chr19_55396787_+SINEAluName=AluY
ADediting_783031chr19_55396960_+SINEAluName=AluJb
ADediting_783032chr19_55396997_+SINEAluName=AluJb
ADediting_783033chr19_55397460_+SINEAluName=AluY
ADediting_783034chr19_55398009_+SINEAluName=AluSz6
ADediting_783035chr19_55398010_+SINEAluName=AluSz6
ADediting_783036chr19_55398075_+SINEAluName=AluSz6
ADediting_783037chr19_55398076_+SINEAluName=AluSz6
ADediting_1559121chr19_55389272_+SINEAluName=AluJr
ADediting_1559122chr19_55390331_+SINEAluName=AluSz
ADediting_1559123chr19_55393911_+SINEAluName=AluSx1
ADediting_1559124chr19_55394212_+SINEAluName=AluSc8
ADediting_1559125chr19_55394603_+SINEAluName=AluJr
ADediting_1559126chr19_55395214_+SINEAluName=AluSz
ADediting_1559127chr19_55395717_+SINEAluName=AluY
ADediting_1559128chr19_55396928_+SINEAluName=AluJb
ADediting_1559129chr19_55398874_+SINEAluName=AluSz
ADediting_1631695chr19_55394244_+SINEAluName=AluSc8

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RNA A-to-I editing events in the alternative splicing sites for RPL28

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for RPL28

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs