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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for MIIP

check button Gene summary
Gene informationGene symbol

MIIP

Gene ID

60672

Gene namemigration and invasion inhibitory protein
SynonymsIIP45
Cytomap

1p36.22

Type of geneprotein-coding
Descriptionmigration and invasion-inhibitory proteinIGFBP2-binding proteininvasion-inhibitory protein 45
Modification date20200313
UniProtAcc

Q5JXC2,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for MIIP

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_11543(12020801, +), ADediting_11544(12020813, +), ADediting_11545(12020823, +), ADediting_11546(12023122, +), ADediting_11547(12023140, +), ADediting_11548(12023150, +), ADediting_11549(12023164, +), ADediting_11550(12023243, +), ADediting_11551(12023273, +), ADediting_11552(12023311, +), ADediting_11553(12023332, +), ADediting_11554(12023468, +), ADediting_11555(12023497, +), ADediting_11556(12023543, +), ADediting_11557(12023545, +), ADediting_11558(12023598, +), ADediting_11559(12023639, +), ADediting_11560(12023640, +), ADediting_11561(12023652, +), ADediting_11562(12023658, +), ADediting_11563(12023740, +), ADediting_11564(12023741, +), ADediting_11565(12023746, +), ADediting_11566(12023829, +), ADediting_11567(12023832, +), ADediting_11568(12023833, +), ADediting_11569(12023834, +), ADediting_11570(12023835, +), ADediting_11571(12023836, +), ADediting_11572(12023838, +), ADediting_11573(12023847, +), ADediting_11574(12023871, +), ADediting_11575(12023873, +), ADediting_11576(12023874, +), ADediting_11577(12023879, +), ADediting_11578(12023883, +), ADediting_11579(12023900, +), ADediting_11580(12023901, +), ADediting_11581(12023915, +), ADediting_11582(12023935, +), ADediting_11583(12023951, +), ADediting_11584(12024457, +), ADediting_11585(12024462, +), ADediting_11586(12024470, +), ADediting_11587(12024478, +), ADediting_11588(12024494, +), ADediting_11589(12024513, +), ADediting_11590(12024514, +), ADediting_11591(12024531, +), ADediting_11592(12024543, +), ADediting_11593(12024553, +), ADediting_11594(12024594, +), ADediting_11595(12024597, +), ADediting_11596(12024602, +), ADediting_11597(12024611, +), ADediting_11598(12024663, +), ADediting_11599(12024673, +), ADediting_11600(12025103, +), ADediting_11601(12025140, +), ADediting_11602(12025201, +), ADediting_11603(12025221, +), ADediting_11604(12025240, +), ADediting_11605(12025295, +), ADediting_11606(12025322, +), ADediting_11607(12025781, +), ADediting_11608(12025815, +), ADediting_11609(12025823, +), ADediting_11610(12025827, +), ADediting_11611(12025837, +), ADediting_11612(12025839, +), ADediting_11613(12025847, +), ADediting_11614(12025872, +), ADediting_11615(12025878, +), ADediting_11616(12025881, +), ADediting_11617(12025932, +), ADediting_11618(12026050, +), ADediting_11619(12026066, +), ADediting_11620(12026081, +), ADediting_11621(12026082, +), ADediting_11622(12026085, +), ADediting_11623(12026095, +), ADediting_11624(12026109, +), ADediting_11625(12026115, +), ADediting_11626(12026129, +), ADediting_11627(12026143, +), ADediting_11628(12026145, +), ADediting_11629(12026147, +), ADediting_11630(12026149, +), ADediting_11631(12026152, +), ADediting_11632(12026153, +), ADediting_11633(12026154, +), ADediting_11634(12026155, +), ADediting_11635(12026158, +), ADediting_11636(12026162, +), ADediting_11637(12026182, +), ADediting_11638(12026184, +), ADediting_11639(12026185, +), ADediting_11640(12026194, +), ADediting_11641(12026198, +), ADediting_11642(12026211, +), ADediting_11643(12026217, +), ADediting_11644(12026225, +), ADediting_11645(12026230, +), ADediting_11646(12026234, +), ADediting_11647(12026250, +), ADediting_11648(12026253, +), ADediting_11649(12026260, +), ADediting_11650(12026288, +), ADediting_11651(12026289, +), ADediting_11652(12027078, +), ADediting_11653(12027089, +), ADediting_11654(12027102, +), ADediting_11655(12027108, +), ADediting_11656(12027109, +), ADediting_11657(12027126, +), ADediting_11658(12027148, +), ADediting_11659(12027154, +), ADediting_11660(12027158, +), ADediting_11661(12027199, +), ADediting_11662(12027219, +), ADediting_11663(12027272, +), ADediting_11664(12027290, +), ADediting_11665(12027957, +), ADediting_11666(12027962, +), ADediting_11667(12027983, +), ADediting_11668(12027997, +), ADediting_11669(12028021, +), ADediting_11670(12028031, +), ADediting_11671(12028042, +), ADediting_11672(12028047, +), ADediting_11673(12028051, +), ADediting_11674(12028054, +), ADediting_11675(12028055, +), ADediting_11676(12028056, +), ADediting_11677(12028057, +), ADediting_11678(12028060, +), ADediting_11679(12028111, +), ADediting_11680(12028127, +), ADediting_11681(12028128, +), ADediting_11682(12028139, +), ADediting_11683(12030624, +), ADediting_11684(12030707, +), ADediting_11685(12030720, +), ADediting_11686(12031801, +), ADediting_1514175(12023238, +), ADediting_1514176(12023595, +), ADediting_1514177(12023939, +), ADediting_1514178(12025134, +), ADediting_1514179(12025146, +), ADediting_1514180(12025199, +), ADediting_1514181(12025225, +), ADediting_1514182(12025243, +), ADediting_1514183(12025864, +), ADediting_1514184(12026276, +), ADediting_1514185(12027134, +), ADediting_1514186(12027150, +), ADediting_1514187(12027170, +), ADediting_1514188(12027183, +), ADediting_1514189(12027189, +), ADediting_1514190(12028006, +), ADediting_1514191(12028049, +), ADediting_1514192(12028148, +), ADediting_1514193(12028167, +), ADediting_1514194(12030632, +), ADediting_1514195(12030725, +),

Top

RNA editing positional annotations for MIIP using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred
ADediting_11686chr1_12031801_+nonsynonymous SNVENST00000235332.6c.A1160Gp.K387R0.00.131-0.28

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_11543chr1_12020801_+intronic
ADediting_11544chr1_12020813_+intronic
ADediting_11545chr1_12020823_+intronic
ADediting_11546chr1_12023122_+intronic
ADediting_11547chr1_12023140_+intronic
ADediting_11548chr1_12023150_+intronic
ADediting_11549chr1_12023164_+intronic
ADediting_11550chr1_12023243_+intronic
ADediting_11551chr1_12023273_+intronic
ADediting_11552chr1_12023311_+intronic
ADediting_11553chr1_12023332_+intronic
ADediting_11554chr1_12023468_+intronic
ADediting_11555chr1_12023497_+intronic
ADediting_11556chr1_12023543_+intronic
ADediting_11557chr1_12023545_+intronic
ADediting_11558chr1_12023598_+intronic
ADediting_11559chr1_12023639_+intronic
ADediting_11560chr1_12023640_+intronic
ADediting_11561chr1_12023652_+intronic
ADediting_11562chr1_12023658_+intronic
ADediting_11563chr1_12023740_+intronic
ADediting_11564chr1_12023741_+intronic
ADediting_11565chr1_12023746_+intronic
ADediting_11566chr1_12023829_+intronic
ADediting_11567chr1_12023832_+intronic
ADediting_11568chr1_12023833_+intronic
ADediting_11569chr1_12023834_+intronic
ADediting_11570chr1_12023835_+intronic
ADediting_11571chr1_12023836_+intronic
ADediting_11572chr1_12023838_+intronic
ADediting_11573chr1_12023847_+intronic
ADediting_11574chr1_12023871_+intronic
ADediting_11575chr1_12023873_+intronic
ADediting_11576chr1_12023874_+intronic
ADediting_11577chr1_12023879_+intronic
ADediting_11578chr1_12023883_+intronic
ADediting_11579chr1_12023900_+intronic
ADediting_11580chr1_12023901_+intronic
ADediting_11581chr1_12023915_+intronic
ADediting_11582chr1_12023935_+intronic
ADediting_11583chr1_12023951_+intronic
ADediting_11584chr1_12024457_+intronic
ADediting_11585chr1_12024462_+intronic
ADediting_11586chr1_12024470_+intronic
ADediting_11587chr1_12024478_+intronic
ADediting_11588chr1_12024494_+intronic
ADediting_11589chr1_12024513_+intronic
ADediting_11590chr1_12024514_+intronic
ADediting_11591chr1_12024531_+intronic
ADediting_11592chr1_12024543_+intronic
ADediting_11593chr1_12024553_+intronic
ADediting_11594chr1_12024594_+intronic
ADediting_11595chr1_12024597_+intronic
ADediting_11596chr1_12024602_+intronic
ADediting_11597chr1_12024611_+intronic
ADediting_11598chr1_12024663_+intronic
ADediting_11599chr1_12024673_+intronic
ADediting_11600chr1_12025103_+intronic
ADediting_11601chr1_12025140_+intronic
ADediting_11602chr1_12025201_+intronic
ADediting_11603chr1_12025221_+intronic
ADediting_11604chr1_12025240_+intronic
ADediting_11605chr1_12025295_+intronic
ADediting_11606chr1_12025322_+intronic
ADediting_11607chr1_12025781_+intronic
ADediting_11608chr1_12025815_+intronic
ADediting_11609chr1_12025823_+intronic
ADediting_11610chr1_12025827_+intronic
ADediting_11611chr1_12025837_+intronic
ADediting_11612chr1_12025839_+intronic
ADediting_11613chr1_12025847_+intronic
ADediting_11614chr1_12025872_+intronic
ADediting_11615chr1_12025878_+intronic
ADediting_11616chr1_12025881_+intronic
ADediting_11617chr1_12025932_+intronic
ADediting_11618chr1_12026050_+intronic
ADediting_11619chr1_12026066_+intronic
ADediting_11620chr1_12026081_+intronic
ADediting_11621chr1_12026082_+intronic
ADediting_11622chr1_12026085_+intronic
ADediting_11623chr1_12026095_+intronic
ADediting_11624chr1_12026109_+intronic
ADediting_11625chr1_12026115_+intronic
ADediting_11626chr1_12026129_+intronic
ADediting_11627chr1_12026143_+intronic
ADediting_11628chr1_12026145_+intronic
ADediting_11629chr1_12026147_+intronic
ADediting_11630chr1_12026149_+intronic
ADediting_11631chr1_12026152_+intronic
ADediting_11632chr1_12026153_+intronic
ADediting_11633chr1_12026154_+intronic
ADediting_11634chr1_12026155_+intronic
ADediting_11635chr1_12026158_+intronic
ADediting_11636chr1_12026162_+intronic
ADediting_11637chr1_12026182_+intronic
ADediting_11638chr1_12026184_+intronic
ADediting_11639chr1_12026185_+intronic
ADediting_11640chr1_12026194_+intronic
ADediting_11641chr1_12026198_+intronic
ADediting_11642chr1_12026211_+intronic
ADediting_11643chr1_12026217_+intronic
ADediting_11644chr1_12026225_+intronic
ADediting_11645chr1_12026230_+intronic
ADediting_11646chr1_12026234_+intronic
ADediting_11647chr1_12026250_+intronic
ADediting_11648chr1_12026253_+intronic
ADediting_11649chr1_12026260_+intronic
ADediting_11650chr1_12026288_+intronic
ADediting_11651chr1_12026289_+intronic
ADediting_11652chr1_12027078_+intronic
ADediting_11653chr1_12027089_+intronic
ADediting_11654chr1_12027102_+intronic
ADediting_11655chr1_12027108_+intronic
ADediting_11656chr1_12027109_+intronic
ADediting_11657chr1_12027126_+intronic
ADediting_11658chr1_12027148_+intronic
ADediting_11659chr1_12027154_+intronic
ADediting_11660chr1_12027158_+intronic
ADediting_11661chr1_12027199_+intronic
ADediting_11662chr1_12027219_+intronic
ADediting_11663chr1_12027272_+intronic
ADediting_11664chr1_12027290_+intronic
ADediting_11665chr1_12027957_+intronic
ADediting_11666chr1_12027962_+intronic
ADediting_11667chr1_12027983_+intronic
ADediting_11668chr1_12027997_+intronic
ADediting_11669chr1_12028021_+intronic
ADediting_11670chr1_12028031_+intronic
ADediting_11671chr1_12028042_+intronic
ADediting_11672chr1_12028047_+intronic
ADediting_11673chr1_12028051_+intronic
ADediting_11674chr1_12028054_+intronic
ADediting_11675chr1_12028055_+intronic
ADediting_11676chr1_12028056_+intronic
ADediting_11677chr1_12028057_+intronic
ADediting_11678chr1_12028060_+intronic
ADediting_11679chr1_12028111_+intronic
ADediting_11680chr1_12028127_+intronic
ADediting_11681chr1_12028128_+intronic
ADediting_11682chr1_12028139_+intronic
ADediting_11683chr1_12030624_+intronic
ADediting_11684chr1_12030707_+intronic
ADediting_11685chr1_12030720_+intronic
ADediting_11686chr1_12031801_+exonic
ADediting_1514175chr1_12023238_+intronic
ADediting_1514176chr1_12023595_+intronic
ADediting_1514177chr1_12023939_+intronic
ADediting_1514178chr1_12025134_+intronic
ADediting_1514179chr1_12025146_+intronic
ADediting_1514180chr1_12025199_+intronic
ADediting_1514181chr1_12025225_+intronic
ADediting_1514182chr1_12025243_+intronic
ADediting_1514183chr1_12025864_+intronic
ADediting_1514184chr1_12026276_+intronic
ADediting_1514185chr1_12027134_+intronic
ADediting_1514186chr1_12027150_+intronic
ADediting_1514187chr1_12027170_+intronic
ADediting_1514188chr1_12027183_+intronic
ADediting_1514189chr1_12027189_+intronic
ADediting_1514190chr1_12028006_+intronic
ADediting_1514191chr1_12028049_+intronic
ADediting_1514192chr1_12028148_+intronic
ADediting_1514193chr1_12028167_+intronic
ADediting_1514194chr1_12030632_+intronic
ADediting_1514195chr1_12030725_+intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_11543chr1_12020801_+SINEAluName=AluSx
ADediting_11544chr1_12020813_+SINEAluName=AluSx
ADediting_11545chr1_12020823_+SINEAluName=AluSx
ADediting_11546chr1_12023122_+SINEAluName=AluSz
ADediting_11547chr1_12023140_+SINEAluName=AluSz
ADediting_11548chr1_12023150_+SINEAluName=AluSz
ADediting_11549chr1_12023164_+SINEAluName=AluSz
ADediting_11550chr1_12023243_+SINEAluName=AluSz
ADediting_11551chr1_12023273_+SINEAluName=AluSz
ADediting_11552chr1_12023311_+SINEAluName=AluSz
ADediting_11553chr1_12023332_+SINEAluName=AluSz
ADediting_11554chr1_12023468_+SINEAluName=AluYc
ADediting_11555chr1_12023497_+SINEAluName=AluYc
ADediting_11556chr1_12023543_+SINEAluName=AluYc
ADediting_11557chr1_12023545_+SINEAluName=AluYc
ADediting_11558chr1_12023598_+SINEAluName=AluYc
ADediting_11559chr1_12023639_+SINEAluName=AluYc
ADediting_11560chr1_12023640_+SINEAluName=AluYc
ADediting_11561chr1_12023652_+SINEAluName=AluYc
ADediting_11562chr1_12023658_+SINEAluName=AluYc
ADediting_11563chr1_12023740_+SINEAluName=AluSg
ADediting_11564chr1_12023741_+SINEAluName=AluSg
ADediting_11565chr1_12023746_+SINEAluName=AluSg
ADediting_11566chr1_12023829_+SINEAluName=AluSg
ADediting_11567chr1_12023832_+SINEAluName=AluSg
ADediting_11568chr1_12023833_+SINEAluName=AluSg
ADediting_11569chr1_12023834_+SINEAluName=AluSg
ADediting_11570chr1_12023835_+SINEAluName=AluSg
ADediting_11571chr1_12023836_+SINEAluName=AluSg
ADediting_11572chr1_12023838_+SINEAluName=AluSg
ADediting_11573chr1_12023847_+SINEAluName=AluSg
ADediting_11574chr1_12023871_+SINEAluName=AluSg
ADediting_11575chr1_12023873_+SINEAluName=AluSg
ADediting_11576chr1_12023874_+SINEAluName=AluSg
ADediting_11577chr1_12023879_+SINEAluName=AluSg
ADediting_11578chr1_12023883_+SINEAluName=AluSg
ADediting_11579chr1_12023900_+SINEAluName=AluSg
ADediting_11580chr1_12023901_+SINEAluName=AluSg
ADediting_11581chr1_12023915_+SINEAluName=AluSg
ADediting_11582chr1_12023935_+SINEAluName=AluSg
ADediting_11583chr1_12023951_+SINEAluName=AluSg
ADediting_11584chr1_12024457_+SINEAluName=AluSq2
ADediting_11585chr1_12024462_+SINEAluName=AluSq2
ADediting_11586chr1_12024470_+SINEAluName=AluSq2
ADediting_11587chr1_12024478_+SINEAluName=AluSq2
ADediting_11588chr1_12024494_+SINEAluName=AluSq2
ADediting_11589chr1_12024513_+SINEAluName=AluSq2
ADediting_11590chr1_12024514_+SINEAluName=AluSq2
ADediting_11591chr1_12024531_+SINEAluName=AluSq2
ADediting_11592chr1_12024543_+SINEAluName=AluSq2
ADediting_11593chr1_12024553_+SINEAluName=AluSq2
ADediting_11594chr1_12024594_+SINEAluName=AluSq2
ADediting_11595chr1_12024597_+SINEAluName=AluSq2
ADediting_11596chr1_12024602_+SINEAluName=AluSq2
ADediting_11597chr1_12024611_+SINEAluName=AluSq2
ADediting_11598chr1_12024663_+SINEAluName=AluSq2
ADediting_11599chr1_12024673_+SINEAluName=AluSq2
ADediting_11600chr1_12025103_+SINEAluName=AluSz6
ADediting_11601chr1_12025140_+SINEAluName=AluSz6
ADediting_11602chr1_12025201_+SINEAluName=AluSz6
ADediting_11603chr1_12025221_+SINEAluName=AluSz6
ADediting_11604chr1_12025240_+SINEAluName=AluSz6
ADediting_11605chr1_12025295_+SINEAluName=AluSz6
ADediting_11606chr1_12025322_+SINEAluName=AluSz6
ADediting_11607chr1_12025781_+SINEAluName=AluSq
ADediting_11608chr1_12025815_+SINEAluName=AluSq
ADediting_11609chr1_12025823_+SINEAluName=AluSq
ADediting_11610chr1_12025827_+SINEAluName=AluSq
ADediting_11611chr1_12025837_+SINEAluName=AluSq
ADediting_11612chr1_12025839_+SINEAluName=AluSq
ADediting_11613chr1_12025847_+SINEAluName=AluSq
ADediting_11614chr1_12025872_+SINEAluName=AluSq
ADediting_11615chr1_12025878_+SINEAluName=AluSq
ADediting_11616chr1_12025881_+SINEAluName=AluSq
ADediting_11617chr1_12025932_+SINEAluName=AluSq
ADediting_11618chr1_12026050_+SINEAluName=AluSx1
ADediting_11619chr1_12026066_+SINEAluName=AluSx1
ADediting_11620chr1_12026081_+SINEAluName=AluSx1
ADediting_11621chr1_12026082_+SINEAluName=AluSx1
ADediting_11622chr1_12026085_+SINEAluName=AluSx1
ADediting_11623chr1_12026095_+SINEAluName=AluSx1
ADediting_11624chr1_12026109_+SINEAluName=AluSx1
ADediting_11625chr1_12026115_+SINEAluName=AluSx1
ADediting_11626chr1_12026129_+SINEAluName=AluSx1
ADediting_11627chr1_12026143_+SINEAluName=AluSx1
ADediting_11628chr1_12026145_+SINEAluName=AluSx1
ADediting_11629chr1_12026147_+SINEAluName=AluSx1
ADediting_11630chr1_12026149_+SINEAluName=AluSx1
ADediting_11631chr1_12026152_+SINEAluName=AluSx1
ADediting_11632chr1_12026153_+SINEAluName=AluSx1
ADediting_11633chr1_12026154_+SINEAluName=AluSx1
ADediting_11634chr1_12026155_+SINEAluName=AluSx1
ADediting_11635chr1_12026158_+SINEAluName=AluSx1
ADediting_11636chr1_12026162_+SINEAluName=AluSx1
ADediting_11637chr1_12026182_+SINEAluName=AluSx1
ADediting_11638chr1_12026184_+SINEAluName=AluSx1
ADediting_11639chr1_12026185_+SINEAluName=AluSx1
ADediting_11640chr1_12026194_+SINEAluName=AluSx1
ADediting_11641chr1_12026198_+SINEAluName=AluSx1
ADediting_11642chr1_12026211_+SINEAluName=AluSx1
ADediting_11643chr1_12026217_+SINEAluName=AluSx1
ADediting_11644chr1_12026225_+SINEAluName=AluSx1
ADediting_11645chr1_12026230_+SINEAluName=AluSx1
ADediting_11646chr1_12026234_+SINEAluName=AluSx1
ADediting_11647chr1_12026250_+SINEAluName=AluSx1
ADediting_11648chr1_12026253_+SINEAluName=AluSx1
ADediting_11649chr1_12026260_+SINEAluName=AluSx1
ADediting_11650chr1_12026288_+SINEAluName=AluSx1
ADediting_11651chr1_12026289_+SINEAluName=AluSx1
ADediting_11652chr1_12027078_+SINEAluName=AluSz
ADediting_11653chr1_12027089_+SINEAluName=AluSz
ADediting_11654chr1_12027102_+SINEAluName=AluSz
ADediting_11655chr1_12027108_+SINEAluName=AluSz
ADediting_11656chr1_12027109_+SINEAluName=AluSz
ADediting_11657chr1_12027126_+SINEAluName=AluSz
ADediting_11658chr1_12027148_+SINEAluName=AluSz
ADediting_11659chr1_12027154_+SINEAluName=AluSz
ADediting_11660chr1_12027158_+SINEAluName=AluSz
ADediting_11661chr1_12027199_+SINEAluName=AluSz
ADediting_11662chr1_12027219_+SINEAluName=AluSz
ADediting_11663chr1_12027272_+SINEAluName=AluSz
ADediting_11664chr1_12027290_+SINEAluName=AluSz
ADediting_11665chr1_12027957_+SINEAluName=AluSg
ADediting_11666chr1_12027962_+SINEAluName=AluSg
ADediting_11667chr1_12027983_+SINEAluName=AluSg
ADediting_11668chr1_12027997_+SINEAluName=AluSg
ADediting_11669chr1_12028021_+SINEAluName=AluSg
ADediting_11670chr1_12028031_+SINEAluName=AluSg
ADediting_11671chr1_12028042_+SINEAluName=AluSg
ADediting_11672chr1_12028047_+SINEAluName=AluSg
ADediting_11673chr1_12028051_+SINEAluName=AluSg
ADediting_11674chr1_12028054_+SINEAluName=AluSg
ADediting_11675chr1_12028055_+SINEAluName=AluSg
ADediting_11676chr1_12028056_+SINEAluName=AluSg
ADediting_11677chr1_12028057_+SINEAluName=AluSg
ADediting_11678chr1_12028060_+SINEAluName=AluSg
ADediting_11679chr1_12028111_+SINEAluName=AluSg
ADediting_11680chr1_12028127_+SINEAluName=AluSg
ADediting_11681chr1_12028128_+SINEAluName=AluSg
ADediting_11682chr1_12028139_+SINEAluName=AluSg
ADediting_11683chr1_12030624_+SINEAluName=AluSq
ADediting_11684chr1_12030707_+SINEAluName=AluSx3
ADediting_11685chr1_12030720_+SINEAluName=AluSx3
ADediting_1514175chr1_12023238_+SINEAluName=AluSz
ADediting_1514176chr1_12023595_+SINEAluName=AluYc
ADediting_1514177chr1_12023939_+SINEAluName=AluSg
ADediting_1514178chr1_12025134_+SINEAluName=AluSz6
ADediting_1514179chr1_12025146_+SINEAluName=AluSz6
ADediting_1514180chr1_12025199_+SINEAluName=AluSz6
ADediting_1514181chr1_12025225_+SINEAluName=AluSz6
ADediting_1514182chr1_12025243_+SINEAluName=AluSz6
ADediting_1514183chr1_12025864_+SINEAluName=AluSq
ADediting_1514184chr1_12026276_+SINEAluName=AluSx1
ADediting_1514185chr1_12027134_+SINEAluName=AluSz
ADediting_1514186chr1_12027150_+SINEAluName=AluSz
ADediting_1514187chr1_12027170_+SINEAluName=AluSz
ADediting_1514188chr1_12027183_+SINEAluName=AluSz
ADediting_1514189chr1_12027189_+SINEAluName=AluSz
ADediting_1514190chr1_12028006_+SINEAluName=AluSg
ADediting_1514191chr1_12028049_+SINEAluName=AluSg
ADediting_1514192chr1_12028148_+SINEAluName=AluSg
ADediting_1514193chr1_12028167_+SINEAluName=AluSg
ADediting_1514194chr1_12030632_+SINEAluName=AluSq
ADediting_1514195chr1_12030725_+SINEAluName=AluSx3

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RNA A-to-I editing events in the alternative splicing sites for MIIP

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for MIIP

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
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Soverview

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for MIIP

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.
all structure


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The effects of the RNA editing to the miRNA binding sites for MIIP

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_11686chr1_12031801_+ENSG00000116691.11ENST00000460823.1MIIP-202hsa-miR-4512chr112031800120318067mer-m81203178512031807149-27.03
ADediting_11686chr1_12031801_+ENSG00000116691.11ENST00000460823.1MIIP-202hsa-miR-4757-5pchr112031798120318047mer-m81203178312031805151-24.21
ADediting_11686chr1_12031801_+ENSG00000116691.11ENST00000460823.1MIIP-202hsa-miR-6744-3pchr112031798120318047mer-m81203178312031805149-21.73
ADediting_11686chr1_12031801_+ENSG00000116691.11ENST00000466860.5MIIP-203hsa-miR-4512chr112031800120318067mer-m81203178512031807149-27.03
ADediting_11686chr1_12031801_+ENSG00000116691.11ENST00000466860.5MIIP-203hsa-miR-4757-5pchr112031798120318047mer-m81203178312031805151-24.21
ADediting_11686chr1_12031801_+ENSG00000116691.11ENST00000466860.5MIIP-203hsa-miR-6744-3pchr112031798120318047mer-m81203178312031805149-21.73
ADediting_11686chr1_12031801_+ENSG00000116691.11ENST00000478299.1MIIP-204hsa-miR-4512chr112031800120318067mer-m81203178512031807149-27.03
ADediting_11686chr1_12031801_+ENSG00000116691.11ENST00000478299.1MIIP-204hsa-miR-4757-5pchr112031798120318047mer-m81203178312031805151-24.21
ADediting_11686chr1_12031801_+ENSG00000116691.11ENST00000478299.1MIIP-204hsa-miR-6744-3pchr112031798120318047mer-m81203178312031805149-21.73
ADediting_11686chr1_12031801_+ENSG00000116691.11ENST00000498685.5MIIP-207hsa-miR-4512chr112031800120318067mer-m81203178512031807149-27.03
ADediting_11686chr1_12031801_+ENSG00000116691.11ENST00000498685.5MIIP-207hsa-miR-4757-5pchr112031798120318047mer-m81203178312031805151-24.21
ADediting_11686chr1_12031801_+ENSG00000116691.11ENST00000498685.5MIIP-207hsa-miR-6744-3pchr112031798120318047mer-m81203178312031805149-21.73

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_11686chr1_12031801_+ENSG00000116691.11ENST00000460823.1MIIP-202hsa-miR-3158-3pchr112031800120318067mer-m81203178612031807152-22.02
ADediting_11686chr1_12031801_+ENSG00000116691.11ENST00000460823.1MIIP-202hsa-miR-6738-3pchr112031795120318017mer-m81203177812031802141-16.83
ADediting_11686chr1_12031801_+ENSG00000116691.11ENST00000460823.1MIIP-202hsa-miR-6815-3pchr112031798120318047mer-m81203178512031805144-13.84
ADediting_11686chr1_12031801_+ENSG00000116691.11ENST00000466860.5MIIP-203hsa-miR-3158-3pchr112031800120318067mer-m81203178612031807152-22.02
ADediting_11686chr1_12031801_+ENSG00000116691.11ENST00000466860.5MIIP-203hsa-miR-6738-3pchr112031795120318017mer-m81203177812031802141-16.83
ADediting_11686chr1_12031801_+ENSG00000116691.11ENST00000466860.5MIIP-203hsa-miR-6815-3pchr112031798120318047mer-m81203178512031805144-13.84
ADediting_11686chr1_12031801_+ENSG00000116691.11ENST00000478299.1MIIP-204hsa-miR-3158-3pchr112031800120318067mer-m81203178612031807152-22.02
ADediting_11686chr1_12031801_+ENSG00000116691.11ENST00000478299.1MIIP-204hsa-miR-6738-3pchr112031795120318017mer-m81203177812031802141-16.83
ADediting_11686chr1_12031801_+ENSG00000116691.11ENST00000478299.1MIIP-204hsa-miR-6815-3pchr112031798120318047mer-m81203178512031805144-13.84
ADediting_11686chr1_12031801_+ENSG00000116691.11ENST00000498685.5MIIP-207hsa-miR-3158-3pchr112031800120318067mer-m81203178612031807152-22.02
ADediting_11686chr1_12031801_+ENSG00000116691.11ENST00000498685.5MIIP-207hsa-miR-6738-3pchr112031795120318017mer-m81203177812031802141-16.83
ADediting_11686chr1_12031801_+ENSG00000116691.11ENST00000498685.5MIIP-207hsa-miR-6815-3pchr112031798120318047mer-m81203178512031805144-13.84

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337757chr7_5495852_-ENSG00000116691.11ENST00000235332.6MIIP-201hsa-miR-589-3pchr112032030120320367mer-m81203201412032037140-12.86

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for MIIP

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000235332.6protein_codingSoverviewSoverview
ENST00000466860.5lncRNASoverviewSoverview
ENST00000498685.5lncRNASoverviewSoverview
ENST00000460823.1lncRNASoverviewSoverview
ENST00000478299.1lncRNASoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_11686ENST00000235332.6chr1_12031801_+1297-698.60-695.40-698.60

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_11686ENST00000466860.5chr1_12031801_+1535-816.60-816.70-816.60
ADediting_11686ENST00000498685.5chr1_12031801_+1150-665.30-664.20-665.30
ADediting_11686ENST00000460823.1chr1_12031801_+731-397.30-394.60-397.30
ADediting_11686ENST00000478299.1chr1_12031801_+357-270.20-265.40-270.20

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Relation with ADAR for MIIP

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_11563chr1_12023740_+0.005011569118789290.1590135511440940.8544099196864680.01046378137602947.72679303486951e-220.509036333243086
DLPFCADediting_11564chr1_12023741_+0.000702506196722270.1914496434657590.1819476773305660.07600787421316494.29961748655506e-170.453019045655124
DLPFCADediting_11584chr1_12024457_+0.001745768294518830.1771019344135580.136469227519110.08476358185054318.46198818017407e-150.421737366234963
DLPFCADediting_11586chr1_12024470_+0.001846961494567430.176178212379330.4839871794232870.03989722774492732.68689302795344e-180.468236274256678
DLPFCADediting_11598chr1_12024663_+0.01047148120842590.1452054342376450.2915387828581940.06009449602296338.16719991300121e-130.391780056183657
DLPFCADediting_11652chr1_12027078_+0.0003475153150424880.2018816665852070.18723351370540.07510079676736048.88737320708899e-150.421431214953664
DLPFCADediting_11654chr1_12027102_+7.75282532117074e-050.2225319098080860.09780354495417670.09420291126164831.24465852784236e-110.372368580613135
DLPFCADediting_11655chr1_12027108_+0.001221703777296760.1828532421100190.5528333806345440.03383669327138995.44386949034215e-140.409893866616611
DLPFCADediting_11656chr1_12027109_+0.0008651017982227730.1882586383429780.1506768999366490.08181794883887763.90488466979131e-100.345791349216273
DLPFCADediting_11665chr1_12027957_+0.00132337572116490.1815799081282750.2199602763503830.06986519504621894.61151575350985e-100.344443744469762

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC1.25019303979816e-050.2453117974874180.2662220732859840.06333872072284432.63864772303553e-620.770953883167216
AC1.11883121257557e-520.7812733898181171.24335647374021e-340.6752212365559891.68322743373084e-210.553864495503092
PCC8.54121463200335e-130.4874977853611283.17973585802226e-110.4565466839647697.49038690416348e-060.317753705527598
TCX0.1510248767968310.1178192979996660.0889910570500428-0.1393525233144111.19774487419015e-160.609865644060745
FP1.73111011817387e-120.4968876729300231.83491182837722e-090.4313989056420864.99986478178525e-100.444723502314942
IFG0.0001651764543272210.6836010450969520.0001308158238019510.6910725467086260.01026315104259270.503664565980019
STG2.06458848404275e-090.5969115513551190.0005808609865732010.3676491397790690.003781848666072440.312680296415332

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Relation with AD stages for MIIP

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.

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RelatedDrugs for MIIP

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for MIIP

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource