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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for RGS3 |
 Gene summary |
| Gene information | Gene symbol | RGS3 | Gene ID | 5998 |
| Gene name | regulator of G protein signaling 3 | |
| Synonyms | C2PA|RGP3 | |
| Cytomap | 9q32 | |
| Type of gene | protein-coding | |
| Description | regulator of G-protein signaling 3regulator of G-protein signalling 3 | |
| Modification date | 20200320 | |
| UniProtAcc | P49796, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for RGS3 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_1433199(113500741, +), ADediting_1433200(113500890, +), ADediting_1433201(113500925, +), ADediting_1433202(113545876, +), ADediting_1433203(113552360, +), ADediting_1433204(113552434, +), ADediting_1433205(113552503, +), ADediting_1433206(113552525, +), ADediting_1433207(113552556, +), ADediting_1433208(113553251, +), ADediting_1433209(113553340, +), ADediting_1433210(113593260, +), ADediting_1433211(113596223, +), ADediting_1592052(113593249, +), ADediting_1592053(113593526, +), ADediting_1671708(113550172, +), ADediting_1671709(113550187, +), |
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RNA editing positional annotations for RGS3 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_1433199 | chr9_113500741_+ | intronic |
| ADediting_1433200 | chr9_113500890_+ | intronic |
| ADediting_1433201 | chr9_113500925_+ | intronic |
| ADediting_1433202 | chr9_113545876_+ | intronic |
| ADediting_1433203 | chr9_113552360_+ | intronic |
| ADediting_1433204 | chr9_113552434_+ | intronic |
| ADediting_1433205 | chr9_113552503_+ | intronic |
| ADediting_1433206 | chr9_113552525_+ | intronic |
| ADediting_1433207 | chr9_113552556_+ | intronic |
| ADediting_1433208 | chr9_113553251_+ | intronic |
| ADediting_1433209 | chr9_113553340_+ | intronic |
| ADediting_1433210 | chr9_113593260_+ | intronic |
| ADediting_1433211 | chr9_113596223_+ | intronic |
| ADediting_1592052 | chr9_113593249_+ | intronic |
| ADediting_1592053 | chr9_113593526_+ | UTR5 |
| ADediting_1671708 | chr9_113550172_+ | intronic |
| ADediting_1671709 | chr9_113550187_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_1433199 | chr9_113500741_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1433200 | chr9_113500890_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1433201 | chr9_113500925_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1433202 | chr9_113545876_+ | SINE | MIR | Name=MIR |
| ADediting_1433203 | chr9_113552360_+ | SINE | Alu | Name=AluY |
| ADediting_1433204 | chr9_113552434_+ | SINE | Alu | Name=AluY |
| ADediting_1433205 | chr9_113552503_+ | SINE | Alu | Name=AluY |
| ADediting_1433206 | chr9_113552525_+ | SINE | Alu | Name=AluY |
| ADediting_1433207 | chr9_113552556_+ | SINE | Alu | Name=AluY |
| ADediting_1433208 | chr9_113553251_+ | SINE | Alu | Name=AluJb |
| ADediting_1433209 | chr9_113553340_+ | SINE | Alu | Name=AluJb |
| ADediting_1433211 | chr9_113596223_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1671708 | chr9_113550172_+ | SINE | Alu | Name=AluSx3 |
| ADediting_1671709 | chr9_113550187_+ | SINE | Alu | Name=AluSx3 |
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RNA A-to-I editing events in the alternative splicing sites for RGS3 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for RGS3 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |