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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for RFX2

check button Gene summary
Gene informationGene symbol

RFX2

Gene ID

5990

Gene nameregulatory factor X2
Synonyms-
Cytomap

19p13.3

Type of geneprotein-coding
DescriptionDNA-binding protein RFX2HLA class II regulatory factor RFX2regulatory factor X 2regulatory factor X, 2 (influences HLA class II expression)trans-acting regulatory factor 2
Modification date20200313
UniProtAcc

P48378,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

Top

RNA A-to-I events for RFX2

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_789647(6027791, -), ADediting_789648(6027823, -), ADediting_789649(6027846, -), ADediting_789650(6027853, -), ADediting_789651(6027863, -), ADediting_789652(6027876, -), ADediting_789653(6027885, -), ADediting_789654(6027898, -), ADediting_789655(6027899, -), ADediting_789656(6027901, -), ADediting_789657(6027925, -), ADediting_789658(6027931, -), ADediting_789659(6027934, -), ADediting_789660(6027940, -), ADediting_789661(6027941, -), ADediting_789662(6027959, -), ADediting_789663(6027961, -), ADediting_789664(6027965, -), ADediting_789665(6027966, -), ADediting_789666(6027975, -), ADediting_789667(6027980, -), ADediting_789668(6027981, -), ADediting_789669(6027989, -), ADediting_789670(6027994, -), ADediting_789671(6027999, -), ADediting_789672(6028035, -), ADediting_789673(6028048, -), ADediting_789674(6028840, -), ADediting_789675(6028853, -), ADediting_789676(6028854, -), ADediting_789677(6028857, -), ADediting_789678(6028883, -), ADediting_789679(6028887, -), ADediting_789680(6028955, -), ADediting_789681(6028957, -), ADediting_789682(6028979, -), ADediting_789683(6028992, -), ADediting_789684(6028996, -), ADediting_789685(6028997, -), ADediting_789686(6029022, -), ADediting_789687(6029451, -), ADediting_789688(6029463, -), ADediting_789689(6029482, -), ADediting_789690(6029490, -), ADediting_789691(6029503, -), ADediting_789692(6029504, -), ADediting_789693(6029517, -), ADediting_789694(6029529, -), ADediting_789695(6029537, -), ADediting_789696(6029543, -), ADediting_789697(6029546, -), ADediting_789698(6029552, -), ADediting_789699(6029560, -), ADediting_789700(6029561, -), ADediting_789701(6029585, -), ADediting_789702(6029587, -), ADediting_789703(6029597, -), ADediting_789704(6029600, -), ADediting_789705(6029601, -), ADediting_789706(6029609, -), ADediting_789707(6029616, -), ADediting_789708(6029623, -), ADediting_789709(6029632, -), ADediting_789710(6029648, -), ADediting_789711(6029656, -), ADediting_789712(6029682, -), ADediting_789713(6029694, -), ADediting_789714(6029699, -), ADediting_789715(6031497, -), ADediting_789716(6031498, -), ADediting_789717(6031526, -), ADediting_789718(6031538, -), ADediting_789719(6031648, -), ADediting_789720(6031649, -), ADediting_789721(6031709, -), ADediting_789722(6031719, -), ADediting_789723(6032198, -), ADediting_789724(6032237, -), ADediting_789725(6032246, -), ADediting_789726(6032286, -), ADediting_789727(6032335, -), ADediting_789728(6032336, -), ADediting_789729(6032364, -), ADediting_789730(6032411, -), ADediting_789731(6032416, -), ADediting_789732(6032419, -), ADediting_789733(6032425, -), ADediting_789734(6032865, -), ADediting_789735(6032881, -), ADediting_789736(6032917, -), ADediting_789737(6032959, -), ADediting_789738(6032960, -), ADediting_789739(6032977, -), ADediting_789740(6032983, -), ADediting_789741(6032984, -), ADediting_789742(6033007, -), ADediting_789743(6033008, -), ADediting_789744(6033069, -), ADediting_789745(6033071, -), ADediting_789746(6034173, -), ADediting_789747(6034209, -), ADediting_789748(6034296, -), ADediting_789749(6034305, -), ADediting_789750(6034325, -), ADediting_789751(6034331, -), ADediting_789752(6034367, -), ADediting_789753(6034389, -), ADediting_789754(6034393, -), ADediting_789755(6034399, -), ADediting_789756(6034408, -), ADediting_789757(6034561, -), ADediting_789758(6034580, -), ADediting_789759(6037095, -), ADediting_789760(6038155, -), ADediting_789761(6040673, -), ADediting_789762(6040690, -), ADediting_789763(6045792, -), ADediting_789764(6046336, -), ADediting_789765(6046346, -), ADediting_789766(6046364, -), ADediting_789767(6046481, -), ADediting_789768(6046498, -), ADediting_789769(6046720, -), ADediting_789770(6046818, -), ADediting_789771(6046888, -), ADediting_789772(6046902, -), ADediting_789773(6046993, -), ADediting_789774(6047045, -), ADediting_789775(6062109, -), ADediting_789776(6062118, -), ADediting_789789(6078799, -), ADediting_789790(6078852, -), ADediting_789791(6079022, -), ADediting_789792(6079051, -), ADediting_789793(6079637, -), ADediting_789794(6079653, -), ADediting_789795(6079658, -), ADediting_789796(6079764, -), ADediting_789797(6079823, -), ADediting_789798(6079847, -), ADediting_789799(6080340, -), ADediting_789800(6080803, -), ADediting_789801(6081828, -), ADediting_789802(6081898, -), ADediting_789803(6081906, -), ADediting_789804(6082462, -), ADediting_789805(6082627, -), ADediting_789806(6082699, -), ADediting_789807(6083071, -), ADediting_789808(6083111, -), ADediting_789809(6083134, -), ADediting_789810(6084695, -), ADediting_789811(6084702, -), ADediting_789812(6084731, -), ADediting_789813(6084773, -), ADediting_789814(6084916, -), ADediting_789815(6084926, -), ADediting_789816(6085970, -), ADediting_789817(6086030, -), ADediting_789818(6088336, -), ADediting_789819(6088340, -), ADediting_789820(6088350, -), ADediting_789821(6088376, -), ADediting_789822(6088384, -), ADediting_789823(6088418, -), ADediting_789824(6093284, -), ADediting_789825(6095012, -), ADediting_789826(6095028, -), ADediting_789827(6095049, -), ADediting_789828(6096543, -), ADediting_789829(6097802, -), ADediting_789830(6097829, -), ADediting_789831(6097849, -), ADediting_789832(6097855, -), ADediting_789833(6097856, -), ADediting_789834(6104380, -), ADediting_789835(6104679, -), ADediting_789850(6134329, -), ADediting_789851(6195394, -), ADediting_789852(6195432, -), ADediting_789853(6195505, -), ADediting_789854(6195537, -), ADediting_789855(6195573, -), ADediting_789856(6196736, -), ADediting_789857(6196745, -), ADediting_789858(6196781, -), ADediting_789859(6196845, -), ADediting_789860(6196858, -), ADediting_789861(6196923, -), ADediting_789862(6196924, -), ADediting_789863(6197032, -), ADediting_789864(6197164, -), ADediting_789865(6197583, -), ADediting_789866(6197655, -), ADediting_789867(6197660, -), ADediting_789868(6197661, -), ADediting_789869(6197711, -), ADediting_789870(6197726, -), ADediting_789871(6197777, -), ADediting_789872(6197931, -), ADediting_789873(6197945, -), ADediting_789874(6197955, -), ADediting_789875(6197981, -), ADediting_789876(6198000, -), ADediting_789877(6198107, -), ADediting_789878(6198895, -), ADediting_1559751(6027828, -), ADediting_1559752(6028909, -), ADediting_1559753(6028912, -), ADediting_1559754(6028967, -), ADediting_1559755(6029464, -), ADediting_1559756(6034613, -), ADediting_1559757(6034617, -), ADediting_1559758(6126128, -), ADediting_1559759(6126200, -), ADediting_1559760(6126207, -), ADediting_1559761(6126231, -), ADediting_1559762(6126319, -), ADediting_1559763(6127467, -), ADediting_1559765(6134623, -), ADediting_1559766(6194559, -), ADediting_1559767(6194645, -), ADediting_1559768(6195388, -), ADediting_1559769(6195865, -), ADediting_1559770(6198864, -),

Top

RNA editing positional annotations for RFX2 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_789647chr19_6027791_-intronic
ADediting_789648chr19_6027823_-intronic
ADediting_789649chr19_6027846_-intronic
ADediting_789650chr19_6027853_-intronic
ADediting_789651chr19_6027863_-intronic
ADediting_789652chr19_6027876_-intronic
ADediting_789653chr19_6027885_-intronic
ADediting_789654chr19_6027898_-intronic
ADediting_789655chr19_6027899_-intronic
ADediting_789656chr19_6027901_-intronic
ADediting_789657chr19_6027925_-intronic
ADediting_789658chr19_6027931_-intronic
ADediting_789659chr19_6027934_-intronic
ADediting_789660chr19_6027940_-intronic
ADediting_789661chr19_6027941_-intronic
ADediting_789662chr19_6027959_-intronic
ADediting_789663chr19_6027961_-intronic
ADediting_789664chr19_6027965_-intronic
ADediting_789665chr19_6027966_-intronic
ADediting_789666chr19_6027975_-intronic
ADediting_789667chr19_6027980_-intronic
ADediting_789668chr19_6027981_-intronic
ADediting_789669chr19_6027989_-intronic
ADediting_789670chr19_6027994_-intronic
ADediting_789671chr19_6027999_-intronic
ADediting_789672chr19_6028035_-intronic
ADediting_789673chr19_6028048_-intronic
ADediting_789674chr19_6028840_-intronic
ADediting_789675chr19_6028853_-intronic
ADediting_789676chr19_6028854_-intronic
ADediting_789677chr19_6028857_-intronic
ADediting_789678chr19_6028883_-intronic
ADediting_789679chr19_6028887_-intronic
ADediting_789680chr19_6028955_-intronic
ADediting_789681chr19_6028957_-intronic
ADediting_789682chr19_6028979_-intronic
ADediting_789683chr19_6028992_-intronic
ADediting_789684chr19_6028996_-intronic
ADediting_789685chr19_6028997_-intronic
ADediting_789686chr19_6029022_-intronic
ADediting_789687chr19_6029451_-intronic
ADediting_789688chr19_6029463_-intronic
ADediting_789689chr19_6029482_-intronic
ADediting_789690chr19_6029490_-intronic
ADediting_789691chr19_6029503_-intronic
ADediting_789692chr19_6029504_-intronic
ADediting_789693chr19_6029517_-intronic
ADediting_789694chr19_6029529_-intronic
ADediting_789695chr19_6029537_-intronic
ADediting_789696chr19_6029543_-intronic
ADediting_789697chr19_6029546_-intronic
ADediting_789698chr19_6029552_-intronic
ADediting_789699chr19_6029560_-intronic
ADediting_789700chr19_6029561_-intronic
ADediting_789701chr19_6029585_-intronic
ADediting_789702chr19_6029587_-intronic
ADediting_789703chr19_6029597_-intronic
ADediting_789704chr19_6029600_-intronic
ADediting_789705chr19_6029601_-intronic
ADediting_789706chr19_6029609_-intronic
ADediting_789707chr19_6029616_-intronic
ADediting_789708chr19_6029623_-intronic
ADediting_789709chr19_6029632_-intronic
ADediting_789710chr19_6029648_-intronic
ADediting_789711chr19_6029656_-intronic
ADediting_789712chr19_6029682_-intronic
ADediting_789713chr19_6029694_-intronic
ADediting_789714chr19_6029699_-intronic
ADediting_789715chr19_6031497_-intronic
ADediting_789716chr19_6031498_-intronic
ADediting_789717chr19_6031526_-intronic
ADediting_789718chr19_6031538_-intronic
ADediting_789719chr19_6031648_-intronic
ADediting_789720chr19_6031649_-intronic
ADediting_789721chr19_6031709_-intronic
ADediting_789722chr19_6031719_-intronic
ADediting_789723chr19_6032198_-intronic
ADediting_789724chr19_6032237_-intronic
ADediting_789725chr19_6032246_-intronic
ADediting_789726chr19_6032286_-intronic
ADediting_789727chr19_6032335_-intronic
ADediting_789728chr19_6032336_-intronic
ADediting_789729chr19_6032364_-intronic
ADediting_789730chr19_6032411_-intronic
ADediting_789731chr19_6032416_-intronic
ADediting_789732chr19_6032419_-intronic
ADediting_789733chr19_6032425_-intronic
ADediting_789734chr19_6032865_-intronic
ADediting_789735chr19_6032881_-intronic
ADediting_789736chr19_6032917_-intronic
ADediting_789737chr19_6032959_-intronic
ADediting_789738chr19_6032960_-intronic
ADediting_789739chr19_6032977_-intronic
ADediting_789740chr19_6032983_-intronic
ADediting_789741chr19_6032984_-intronic
ADediting_789742chr19_6033007_-intronic
ADediting_789743chr19_6033008_-intronic
ADediting_789744chr19_6033069_-intronic
ADediting_789745chr19_6033071_-intronic
ADediting_789746chr19_6034173_-intronic
ADediting_789747chr19_6034209_-intronic
ADediting_789748chr19_6034296_-intronic
ADediting_789749chr19_6034305_-intronic
ADediting_789750chr19_6034325_-intronic
ADediting_789751chr19_6034331_-intronic
ADediting_789752chr19_6034367_-intronic
ADediting_789753chr19_6034389_-intronic
ADediting_789754chr19_6034393_-intronic
ADediting_789755chr19_6034399_-intronic
ADediting_789756chr19_6034408_-intronic
ADediting_789757chr19_6034561_-intronic
ADediting_789758chr19_6034580_-intronic
ADediting_789759chr19_6037095_-intronic
ADediting_789760chr19_6038155_-intronic
ADediting_789761chr19_6040673_-intronic
ADediting_789762chr19_6040690_-intronic
ADediting_789763chr19_6045792_-intronic
ADediting_789764chr19_6046336_-intronic
ADediting_789765chr19_6046346_-intronic
ADediting_789766chr19_6046364_-intronic
ADediting_789767chr19_6046481_-intronic
ADediting_789768chr19_6046498_-intronic
ADediting_789769chr19_6046720_-intronic
ADediting_789770chr19_6046818_-intronic
ADediting_789771chr19_6046888_-intronic
ADediting_789772chr19_6046902_-intronic
ADediting_789773chr19_6046993_-intronic
ADediting_789774chr19_6047045_-intronic
ADediting_789775chr19_6062109_-intronic
ADediting_789776chr19_6062118_-intronic
ADediting_789789chr19_6078799_-intronic
ADediting_789790chr19_6078852_-intronic
ADediting_789791chr19_6079022_-intronic
ADediting_789792chr19_6079051_-intronic
ADediting_789793chr19_6079637_-intronic
ADediting_789794chr19_6079653_-intronic
ADediting_789795chr19_6079658_-intronic
ADediting_789796chr19_6079764_-intronic
ADediting_789797chr19_6079823_-intronic
ADediting_789798chr19_6079847_-intronic
ADediting_789799chr19_6080340_-intronic
ADediting_789800chr19_6080803_-intronic
ADediting_789801chr19_6081828_-intronic
ADediting_789802chr19_6081898_-intronic
ADediting_789803chr19_6081906_-intronic
ADediting_789804chr19_6082462_-intronic
ADediting_789805chr19_6082627_-intronic
ADediting_789806chr19_6082699_-intronic
ADediting_789807chr19_6083071_-intronic
ADediting_789808chr19_6083111_-intronic
ADediting_789809chr19_6083134_-intronic
ADediting_789810chr19_6084695_-intronic
ADediting_789811chr19_6084702_-intronic
ADediting_789812chr19_6084731_-intronic
ADediting_789813chr19_6084773_-intronic
ADediting_789814chr19_6084916_-intronic
ADediting_789815chr19_6084926_-intronic
ADediting_789816chr19_6085970_-intronic
ADediting_789817chr19_6086030_-intronic
ADediting_789818chr19_6088336_-intronic
ADediting_789819chr19_6088340_-intronic
ADediting_789820chr19_6088350_-intronic
ADediting_789821chr19_6088376_-intronic
ADediting_789822chr19_6088384_-intronic
ADediting_789823chr19_6088418_-intronic
ADediting_789824chr19_6093284_-intronic
ADediting_789825chr19_6095012_-intronic
ADediting_789826chr19_6095028_-intronic
ADediting_789827chr19_6095049_-intronic
ADediting_789828chr19_6096543_-intronic
ADediting_789829chr19_6097802_-intronic
ADediting_789830chr19_6097829_-intronic
ADediting_789831chr19_6097849_-intronic
ADediting_789832chr19_6097855_-intronic
ADediting_789833chr19_6097856_-intronic
ADediting_789834chr19_6104380_-intronic
ADediting_789835chr19_6104679_-intronic
ADediting_789850chr19_6134329_-intronic
ADediting_789851chr19_6195394_-intronic
ADediting_789852chr19_6195432_-intronic
ADediting_789853chr19_6195505_-intronic
ADediting_789854chr19_6195537_-intronic
ADediting_789855chr19_6195573_-intronic
ADediting_789856chr19_6196736_-intronic
ADediting_789857chr19_6196745_-intronic
ADediting_789858chr19_6196781_-intronic
ADediting_789859chr19_6196845_-intronic
ADediting_789860chr19_6196858_-intronic
ADediting_789861chr19_6196923_-intronic
ADediting_789862chr19_6196924_-intronic
ADediting_789863chr19_6197032_-intronic
ADediting_789864chr19_6197164_-intronic
ADediting_789865chr19_6197583_-intronic
ADediting_789866chr19_6197655_-intronic
ADediting_789867chr19_6197660_-intronic
ADediting_789868chr19_6197661_-intronic
ADediting_789869chr19_6197711_-intronic
ADediting_789870chr19_6197726_-intronic
ADediting_789871chr19_6197777_-intronic
ADediting_789872chr19_6197931_-intronic
ADediting_789873chr19_6197945_-intronic
ADediting_789874chr19_6197955_-intronic
ADediting_789875chr19_6197981_-intronic
ADediting_789876chr19_6198000_-intronic
ADediting_789877chr19_6198107_-intronic
ADediting_789878chr19_6198895_-intronic
ADediting_1559751chr19_6027828_-intronic
ADediting_1559752chr19_6028909_-intronic
ADediting_1559753chr19_6028912_-intronic
ADediting_1559754chr19_6028967_-intronic
ADediting_1559755chr19_6029464_-intronic
ADediting_1559756chr19_6034613_-intronic
ADediting_1559757chr19_6034617_-intronic
ADediting_1559758chr19_6126128_-intronic
ADediting_1559759chr19_6126200_-intronic
ADediting_1559760chr19_6126207_-intronic
ADediting_1559761chr19_6126231_-intronic
ADediting_1559762chr19_6126319_-intronic
ADediting_1559763chr19_6127467_-intronic
ADediting_1559765chr19_6134623_-intronic
ADediting_1559766chr19_6194559_-intronic
ADediting_1559767chr19_6194645_-intronic
ADediting_1559768chr19_6195388_-intronic
ADediting_1559769chr19_6195865_-intronic
ADediting_1559770chr19_6198864_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_789647chr19_6027791_-SINEAluName=AluSz6
ADediting_789648chr19_6027823_-SINEAluName=AluSz6
ADediting_789649chr19_6027846_-SINEAluName=AluSz6
ADediting_789650chr19_6027853_-SINEAluName=AluSz6
ADediting_789651chr19_6027863_-SINEAluName=AluSz6
ADediting_789652chr19_6027876_-SINEAluName=AluSz6
ADediting_789653chr19_6027885_-SINEAluName=AluSz6
ADediting_789654chr19_6027898_-SINEAluName=AluSz6
ADediting_789655chr19_6027899_-SINEAluName=AluSz6
ADediting_789656chr19_6027901_-SINEAluName=AluSz6
ADediting_789657chr19_6027925_-SINEAluName=AluSz6
ADediting_789658chr19_6027931_-SINEAluName=AluSz6
ADediting_789659chr19_6027934_-SINEAluName=AluSz6
ADediting_789660chr19_6027940_-SINEAluName=AluSz6
ADediting_789661chr19_6027941_-SINEAluName=AluSz6
ADediting_789662chr19_6027959_-SINEAluName=AluSz6
ADediting_789663chr19_6027961_-SINEAluName=AluSz6
ADediting_789664chr19_6027965_-SINEAluName=AluSz6
ADediting_789665chr19_6027966_-SINEAluName=AluSz6
ADediting_789666chr19_6027975_-SINEAluName=AluSz6
ADediting_789667chr19_6027980_-SINEAluName=AluSz6
ADediting_789668chr19_6027981_-SINEAluName=AluSz6
ADediting_789669chr19_6027989_-SINEAluName=AluSz6
ADediting_789670chr19_6027994_-SINEAluName=AluSz6
ADediting_789671chr19_6027999_-SINEAluName=AluSz6
ADediting_789672chr19_6028035_-SINEAluName=AluSz6
ADediting_789673chr19_6028048_-SINEAluName=AluSz6
ADediting_789674chr19_6028840_-SINEAluName=AluSz
ADediting_789675chr19_6028853_-SINEAluName=AluSz
ADediting_789676chr19_6028854_-SINEAluName=AluSz
ADediting_789677chr19_6028857_-SINEAluName=AluSz
ADediting_789678chr19_6028883_-SINEAluName=AluSz
ADediting_789679chr19_6028887_-SINEAluName=AluSz
ADediting_789680chr19_6028955_-SINEAluName=AluSz
ADediting_789681chr19_6028957_-SINEAluName=AluSz
ADediting_789682chr19_6028979_-SINEAluName=AluSz
ADediting_789683chr19_6028992_-SINEAluName=AluSz
ADediting_789684chr19_6028996_-SINEAluName=AluSz
ADediting_789685chr19_6028997_-SINEAluName=AluSz
ADediting_789686chr19_6029022_-SINEAluName=AluSz
ADediting_789687chr19_6029451_-SINEAluName=AluSx1
ADediting_789688chr19_6029463_-SINEAluName=AluSx1
ADediting_789689chr19_6029482_-SINEAluName=AluSx1
ADediting_789690chr19_6029490_-SINEAluName=AluSx1
ADediting_789691chr19_6029503_-SINEAluName=AluSx1
ADediting_789692chr19_6029504_-SINEAluName=AluSx1
ADediting_789693chr19_6029517_-SINEAluName=AluSx1
ADediting_789694chr19_6029529_-SINEAluName=AluSx1
ADediting_789695chr19_6029537_-SINEAluName=AluSx1
ADediting_789696chr19_6029543_-SINEAluName=AluSx1
ADediting_789697chr19_6029546_-SINEAluName=AluSx1
ADediting_789698chr19_6029552_-SINEAluName=AluSx1
ADediting_789699chr19_6029560_-SINEAluName=AluSx1
ADediting_789700chr19_6029561_-SINEAluName=AluSx1
ADediting_789701chr19_6029585_-SINEAluName=AluSx1
ADediting_789702chr19_6029587_-SINEAluName=AluSx1
ADediting_789703chr19_6029597_-SINEAluName=AluSx1
ADediting_789704chr19_6029600_-SINEAluName=AluSx1
ADediting_789705chr19_6029601_-SINEAluName=AluSx1
ADediting_789706chr19_6029609_-SINEAluName=AluSx1
ADediting_789707chr19_6029616_-SINEAluName=AluSx1
ADediting_789708chr19_6029623_-SINEAluName=AluSx1
ADediting_789709chr19_6029632_-SINEAluName=AluSx1
ADediting_789710chr19_6029648_-SINEAluName=AluSx1
ADediting_789711chr19_6029656_-SINEAluName=AluSx1
ADediting_789712chr19_6029682_-SINEAluName=AluSx1
ADediting_789713chr19_6029694_-SINEAluName=AluSx1
ADediting_789714chr19_6029699_-SINEAluName=AluSx1
ADediting_789715chr19_6031497_-SINEAluName=AluSx1
ADediting_789716chr19_6031498_-SINEAluName=AluSx1
ADediting_789717chr19_6031526_-SINEAluName=AluSx1
ADediting_789718chr19_6031538_-SINEAluName=AluSx1
ADediting_789719chr19_6031648_-SINEAluName=AluSx1
ADediting_789720chr19_6031649_-SINEAluName=AluSx1
ADediting_789721chr19_6031709_-SINEAluName=AluSx1
ADediting_789722chr19_6031719_-SINEAluName=AluSx1
ADediting_789723chr19_6032198_-SINEAluName=AluSc
ADediting_789724chr19_6032237_-SINEAluName=AluSc
ADediting_789725chr19_6032246_-SINEAluName=AluSc
ADediting_789726chr19_6032286_-SINEAluName=AluSc
ADediting_789727chr19_6032335_-SINEAluName=AluSc
ADediting_789728chr19_6032336_-SINEAluName=AluSc
ADediting_789729chr19_6032364_-SINEAluName=AluSc
ADediting_789730chr19_6032411_-SINEAluName=AluSc
ADediting_789731chr19_6032416_-SINEAluName=AluSc
ADediting_789732chr19_6032419_-SINEAluName=AluSc
ADediting_789733chr19_6032425_-SINEAluName=AluSc
ADediting_789734chr19_6032865_-SINEAluName=AluJo
ADediting_789735chr19_6032881_-SINEAluName=AluJo
ADediting_789736chr19_6032917_-SINEAluName=AluJo
ADediting_789737chr19_6032959_-SINEAluName=AluJo
ADediting_789738chr19_6032960_-SINEAluName=AluJo
ADediting_789739chr19_6032977_-SINEAluName=AluJo
ADediting_789740chr19_6032983_-SINEAluName=AluJo
ADediting_789741chr19_6032984_-SINEAluName=AluJo
ADediting_789742chr19_6033007_-SINEAluName=AluJo
ADediting_789743chr19_6033008_-SINEAluName=AluJo
ADediting_789744chr19_6033069_-SINEAluName=AluJo
ADediting_789745chr19_6033071_-SINEAluName=AluJo
ADediting_789746chr19_6034173_-SINEAluName=AluJb
ADediting_789747chr19_6034209_-SINEAluName=AluJb
ADediting_789748chr19_6034296_-SINEAluName=AluSc
ADediting_789749chr19_6034305_-SINEAluName=AluSc
ADediting_789750chr19_6034325_-SINEAluName=AluSc
ADediting_789751chr19_6034331_-SINEAluName=AluSc
ADediting_789752chr19_6034367_-SINEAluName=AluSc
ADediting_789753chr19_6034389_-SINEAluName=AluSc
ADediting_789754chr19_6034393_-SINEAluName=AluSc
ADediting_789755chr19_6034399_-SINEAluName=AluSc
ADediting_789756chr19_6034408_-SINEAluName=AluSc
ADediting_789757chr19_6034561_-SINEAluName=AluJb
ADediting_789758chr19_6034580_-SINEAluName=AluJb
ADediting_789759chr19_6037095_-SINEAluName=AluY
ADediting_789760chr19_6038155_-SINEAluName=AluSz
ADediting_789761chr19_6040673_-SINEAluName=AluJr
ADediting_789762chr19_6040690_-SINEAluName=AluJr
ADediting_789763chr19_6045792_-SINEAluName=AluSq2
ADediting_789764chr19_6046336_-SINEAluName=AluSx
ADediting_789765chr19_6046346_-SINEAluName=AluSx
ADediting_789766chr19_6046364_-SINEAluName=AluSx
ADediting_789767chr19_6046481_-SINEAluName=AluSx
ADediting_789768chr19_6046498_-SINEAluName=AluSx
ADediting_789769chr19_6046720_-SINEAluName=AluJr
ADediting_789770chr19_6046818_-SINEAluName=AluJr
ADediting_789771chr19_6046888_-SINEAluName=AluJr
ADediting_789772chr19_6046902_-SINEAluName=AluJr
ADediting_789773chr19_6046993_-SINEAluName=AluJr
ADediting_789774chr19_6047045_-SINEAluName=AluJr
ADediting_789775chr19_6062109_-SINEAluName=AluJo
ADediting_789776chr19_6062118_-SINEAluName=AluJo
ADediting_789789chr19_6078799_-SINEAluName=AluSz
ADediting_789790chr19_6078852_-SINEAluName=AluSz
ADediting_789791chr19_6079022_-SINEAluName=AluSz
ADediting_789792chr19_6079051_-SINEAluName=AluSz
ADediting_789793chr19_6079637_-SINEAluName=AluSc5
ADediting_789794chr19_6079653_-SINEAluName=AluSc5
ADediting_789795chr19_6079658_-SINEAluName=AluSc5
ADediting_789796chr19_6079764_-SINEAluName=AluSc5
ADediting_789797chr19_6079823_-SINEAluName=AluSc5
ADediting_789798chr19_6079847_-SINEAluName=AluSc5
ADediting_789799chr19_6080340_-SINEAluName=AluJr4
ADediting_789800chr19_6080803_-SINEAluName=AluSg
ADediting_789801chr19_6081828_-SINEAluName=AluY
ADediting_789802chr19_6081898_-SINEAluName=AluY
ADediting_789803chr19_6081906_-SINEAluName=AluY
ADediting_789804chr19_6082462_-SINEAluName=AluJo
ADediting_789805chr19_6082627_-SINEAluName=AluJo
ADediting_789806chr19_6082699_-SINEAluName=AluJo
ADediting_789807chr19_6083071_-SINEAluName=AluJb
ADediting_789808chr19_6083111_-SINEAluName=AluJb
ADediting_789809chr19_6083134_-SINEAluName=AluJb
ADediting_789810chr19_6084695_-SINEAluName=AluSq
ADediting_789811chr19_6084702_-SINEAluName=AluSq
ADediting_789812chr19_6084731_-SINEAluName=AluSq
ADediting_789813chr19_6084773_-SINEAluName=AluSq
ADediting_789814chr19_6084916_-SINEAluName=AluSq
ADediting_789815chr19_6084926_-SINEAluName=AluSq
ADediting_789816chr19_6085970_-SINEAluName=AluJr
ADediting_789817chr19_6086030_-SINEAluName=AluJr
ADediting_789818chr19_6088336_-SINEAluName=AluSp
ADediting_789819chr19_6088340_-SINEAluName=AluSp
ADediting_789820chr19_6088350_-SINEAluName=AluSp
ADediting_789821chr19_6088376_-SINEAluName=AluSp
ADediting_789822chr19_6088384_-SINEAluName=AluSp
ADediting_789823chr19_6088418_-SINEAluName=AluSp
ADediting_789824chr19_6093284_-SINEAluName=AluSx
ADediting_789825chr19_6095012_-SINEAluName=AluY
ADediting_789826chr19_6095028_-SINEAluName=AluY
ADediting_789827chr19_6095049_-SINEAluName=AluY
ADediting_789828chr19_6096543_-SINEAluName=AluY
ADediting_789829chr19_6097802_-SINEAluName=AluJr
ADediting_789830chr19_6097829_-SINEAluName=AluJr
ADediting_789831chr19_6097849_-SINEAluName=AluJr
ADediting_789832chr19_6097855_-SINEAluName=AluJr
ADediting_789833chr19_6097856_-SINEAluName=AluJr
ADediting_789834chr19_6104380_-SINEAluName=AluY
ADediting_789835chr19_6104679_-SINEAluName=FLAM_A
ADediting_789850chr19_6134329_-SINEAluName=AluSq2
ADediting_789851chr19_6195394_-SINEAluName=AluSx4
ADediting_789852chr19_6195432_-SINEAluName=AluSx4
ADediting_789853chr19_6195505_-SINEAluName=AluSx4
ADediting_789854chr19_6195537_-SINEAluName=AluSx4
ADediting_789855chr19_6195573_-SINEAluName=AluSx4
ADediting_789856chr19_6196736_-SINEAluName=AluY
ADediting_789857chr19_6196745_-SINEAluName=AluY
ADediting_789858chr19_6196781_-SINEAluName=AluY
ADediting_789859chr19_6196845_-SINEAluName=AluY
ADediting_789860chr19_6196858_-SINEAluName=AluY
ADediting_789861chr19_6196923_-SINEAluName=AluY
ADediting_789862chr19_6196924_-SINEAluName=AluY
ADediting_789863chr19_6197032_-SINEAluName=AluY
ADediting_789864chr19_6197164_-SINEAluName=AluY
ADediting_789865chr19_6197583_-SINEAluName=AluSx1
ADediting_789866chr19_6197655_-SINEAluName=AluSx1
ADediting_789867chr19_6197660_-SINEAluName=AluSx1
ADediting_789868chr19_6197661_-SINEAluName=AluSx1
ADediting_789869chr19_6197711_-SINEAluName=AluSx1
ADediting_789870chr19_6197726_-SINEAluName=AluSx1
ADediting_789871chr19_6197777_-SINEAluName=AluSx1
ADediting_789872chr19_6197931_-SINEAluName=AluSx4
ADediting_789873chr19_6197945_-SINEAluName=AluSx4
ADediting_789874chr19_6197955_-SINEAluName=AluSx4
ADediting_789875chr19_6197981_-SINEAluName=AluSx4
ADediting_789876chr19_6198000_-SINEAluName=AluSx4
ADediting_789877chr19_6198107_-SINEAluName=AluSx4
ADediting_789878chr19_6198895_-SINEAluName=AluSq2
ADediting_1559751chr19_6027828_-SINEAluName=AluSz6
ADediting_1559752chr19_6028909_-SINEAluName=AluSz
ADediting_1559753chr19_6028912_-SINEAluName=AluSz
ADediting_1559754chr19_6028967_-SINEAluName=AluSz
ADediting_1559755chr19_6029464_-SINEAluName=AluSx1
ADediting_1559756chr19_6034613_-SINEAluName=AluJb
ADediting_1559757chr19_6034617_-SINEAluName=AluJb
ADediting_1559758chr19_6126128_-SINEAluName=AluJr
ADediting_1559759chr19_6126200_-SINEAluName=AluJr
ADediting_1559760chr19_6126207_-SINEAluName=AluJr
ADediting_1559761chr19_6126231_-SINEAluName=AluJr
ADediting_1559762chr19_6126319_-SINEAluName=AluJr
ADediting_1559763chr19_6127467_-SINEAluName=AluJr
ADediting_1559765chr19_6134623_-SINEAluName=AluJr
ADediting_1559766chr19_6194559_-SINEAluName=AluJr4
ADediting_1559767chr19_6194645_-SINEAluName=AluJr4
ADediting_1559768chr19_6195388_-SINEAluName=AluSx4
ADediting_1559769chr19_6195865_-SINEAluName=AluJr4
ADediting_1559770chr19_6198864_-SINEAluName=AluSq2

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RNA A-to-I editing events in the alternative splicing sites for RFX2

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for RFX2

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for RFX2

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for RFX2


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1097295chr3_85385762_+ENSG00000087903.13ENST00000303657.10RFX2-201hsa-miR-5688chr19599332259933287mer-m859933215993341150-11.33
ADediting_1097295chr3_85385762_+ENSG00000087903.13ENST00000303657.10RFX2-201hsa-miR-5688chr19599372759937337mer-m859937265993747140-11.1
ADediting_1097295chr3_85385762_+ENSG00000087903.13ENST00000303657.10RFX2-201hsa-miR-5688chr19599396559939717mer-m859939645993985154-21.02
ADediting_1097295chr3_85385762_+ENSG00000087903.13ENST00000359161.7RFX2-202hsa-miR-5688chr19599372759937337mer-m859937265993747140-11.1
ADediting_1097295chr3_85385762_+ENSG00000087903.13ENST00000359161.7RFX2-202hsa-miR-5688chr19599396559939717mer-m859939645993985154-21.02
ADediting_1337757chr7_5495852_-ENSG00000087903.13ENST00000303657.10RFX2-201hsa-miR-589-3pchr19599461759946237mer-m859946165994644143-22.74
ADediting_1337757chr7_5495852_-ENSG00000087903.13ENST00000359161.7RFX2-202hsa-miR-589-3pchr19599461759946237mer-m859946165994644143-22.74
ADediting_1337757chr7_5495852_-ENSG00000087903.13ENST00000592546.5RFX2-222hsa-miR-589-3pchr19599461759946237mer-m859946165994644143-22.74
ADediting_291761chr11_93733708_-ENSG00000087903.13ENST00000303657.10RFX2-201hsa-miR-1304-3pchr19599382259938287mer-m859938215993842140-12.91
ADediting_291761chr11_93733708_-ENSG00000087903.13ENST00000359161.7RFX2-202hsa-miR-1304-3pchr19599382259938287mer-m859938215993842140-12.91
ADediting_843620chr2_207754818_+ENSG00000087903.13ENST00000303657.10RFX2-201hsa-miR-4775chr19599405659940638mer-1a59940565994077155-15.71
ADediting_843620chr2_207754818_+ENSG00000087903.13ENST00000359161.7RFX2-202hsa-miR-4775chr19599405659940638mer-1a59940565994077155-15.71

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1556067chr19_40282625_-ENSG00000087903.13ENST00000303657.10RFX2-201hsa-miR-641chr19599327359932797mer-m859932725993295140-10.19
ADediting_1631458chr19_40282624_-ENSG00000087903.13ENST00000303657.10RFX2-201hsa-miR-641chr19599327359932797mer-m859932725993295140-10.19
ADediting_843620chr2_207754818_+ENSG00000087903.13ENST00000303657.10RFX2-201hsa-miR-4775chr19599443059944378mer-1a59944305994453151-8.58
ADediting_843620chr2_207754818_+ENSG00000087903.13ENST00000359161.7RFX2-202hsa-miR-4775chr19599443059944378mer-1a59944305994453151-8.58

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for RFX2

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for RFX2

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_789709chr19_6029632_-0.109890152459540.09097846035020550.424407938224495-0.04552903453572481.67270090229341e-100.352562333641494
DLPFCADediting_789710chr19_6029648_-0.3104521845484630.05779217922202610.660993320603238-0.02500463831161321.61279841449443e-090.334087189632045
DLPFCADediting_789711chr19_6029656_-0.1284824207415170.08652420287524590.501774113869491-0.03829074080682388.51664098016628e-130.391490981426626
CERADediting_789711chr19_6029656_-0.02542222551365170.182472527707416.80141809091631e-050.3193354472365520.09600440873789750.136414255255861
CERADediting_789714chr19_6029699_-0.03572515514509360.1716290135959516.14932165041324e-050.3211477963738120.1062415937065420.13241653022728
DLPFCADediting_789754chr19_6034393_-0.8362132494755890.01178923635253010.157059579335461-0.08056309358816555.70666950723732e-120.378058277888788
DLPFCADediting_789765chr19_6046346_-0.793336483275844-0.01493901159479980.042976527697394-0.1150347975621531.37068247985317e-160.446423894810806
DLPFCADediting_789766chr19_6046364_-0.718675140549164-0.02054050912389320.0439671955477781-0.1144964546985887.49769570516703e-120.376079282863194
DLPFCADediting_789768chr19_6046498_-0.80317464495624-0.01421261759576040.0567088548829168-0.1083467543464145.71537884455224e-120.37804725853943

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC0.0001699336943141860.2119764692525560.0008327548470191580.1888465289351952.4842419555695e-150.429288477342649
AC2.7315804747028e-250.5945691231287361.72871089043782e-110.4087844771338651.85196750463741e-220.564704877432277
PCC0.01944407272684620.1689839641733550.116159511685310.1140581892835125.52586053631767e-140.509018758262277
CER5.94778907529329e-050.3217444529209559.89994633369465e-060.3521564269050612.40462475567571e-160.605027905080044
TCX0.007920091667158280.2160575354674760.434508458348631-0.06428091995035421.40469007863951e-100.49342281316737
FP0.02571072795773330.1671864187857560.2689078204240560.08330961186604073.74505415777043e-110.469680476793594
IFG0.0580086316001970.384100734841810.003137214083923880.5667548442142370.00235305498582890.580393500028898
PG0.0005012093700557640.2527227699732770.02803549261794050.1611087688570172.28175341108365e-060.338571407696092
STG0.8055465684861910.02726344293237350.335142691518232-0.106455873094714.95212785016216e-090.585416690822246

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Relation with AD stages for RFX2

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
CER1.54749742375203e-060.443323618717479
TCX4.51422769672597e-110.585076086476435
PG4.30888858891399e-060.329737588841088

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RelatedDrugs for RFX2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for RFX2

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource
RFX2C0006142Malignant neoplasm of breast1UNIPROT