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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for BBS2 |
 Gene summary |
| Gene information | Gene symbol | BBS2 | Gene ID | 583 |
| Gene name | Bardet-Biedl syndrome 2 | |
| Synonyms | BBS|RP74 | |
| Cytomap | 16q13 | |
| Type of gene | protein-coding | |
| Description | Bardet-Biedl syndrome 2 protein | |
| Modification date | 20200313 | |
| UniProtAcc | Q9BXC9, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
RNA A-to-I events for BBS2 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_546679(56479252, -), ADediting_546680(56480473, -), ADediting_546681(56480478, -), ADediting_546682(56480481, -), ADediting_546683(56480551, -), ADediting_546684(56480555, -), ADediting_546685(56480568, -), ADediting_546686(56480570, -), ADediting_546687(56480573, -), ADediting_546688(56480579, -), ADediting_546689(56480584, -), ADediting_546690(56480647, -), ADediting_546691(56483730, -), ADediting_546692(56483811, -), ADediting_546693(56483824, -), ADediting_546694(56483837, -), ADediting_546695(56483864, -), ADediting_546696(56483878, -), ADediting_546697(56483883, -), ADediting_546698(56483914, -), ADediting_546699(56483951, -), ADediting_546700(56483976, -), ADediting_546701(56484067, -), ADediting_546702(56484118, -), ADediting_546703(56484135, -), ADediting_546704(56484139, -), ADediting_546705(56484145, -), ADediting_546706(56484171, -), ADediting_546707(56484183, -), ADediting_546708(56484185, -), ADediting_546709(56484190, -), ADediting_546710(56484201, -), ADediting_546711(56484202, -), ADediting_546712(56484211, -), ADediting_546713(56486560, -), ADediting_546714(56486785, -), ADediting_546715(56486839, -), ADediting_546716(56486874, -), ADediting_546717(56486887, -), ADediting_546718(56486900, -), ADediting_546719(56486901, -), ADediting_546720(56486923, -), ADediting_546721(56486927, -), ADediting_546722(56488977, -), ADediting_546723(56489000, -), ADediting_546724(56489134, -), ADediting_546725(56489135, -), ADediting_546726(56489136, -), ADediting_546727(56489142, -), ADediting_546728(56489154, -), ADediting_546729(56489159, -), ADediting_546730(56489167, -), ADediting_546731(56489173, -), ADediting_546732(56489219, -), ADediting_546733(56490108, -), ADediting_546734(56490475, -), ADediting_546735(56490478, -), ADediting_546736(56490495, -), ADediting_546737(56490558, -), ADediting_546738(56490565, -), ADediting_546739(56490594, -), ADediting_546740(56490635, -), ADediting_546741(56490858, -), ADediting_546742(56490900, -), ADediting_546743(56490945, -), ADediting_546744(56490956, -), ADediting_546745(56491007, -), ADediting_546746(56491033, -), ADediting_546747(56491034, -), ADediting_546748(56493262, -), ADediting_546749(56493274, -), ADediting_546750(56493291, -), ADediting_546751(56493303, -), ADediting_546752(56493987, -), ADediting_546753(56493988, -), ADediting_546754(56494055, -), ADediting_546755(56494069, -), ADediting_546756(56494083, -), ADediting_546757(56494097, -), ADediting_546758(56494113, -), ADediting_546759(56494167, -), ADediting_546760(56494169, -), ADediting_546761(56494171, -), ADediting_546762(56494181, -), ADediting_546763(56494186, -), ADediting_546764(56494218, -), ADediting_546765(56494235, -), ADediting_546766(56494240, -), ADediting_546767(56494241, -), ADediting_546768(56494254, -), ADediting_546769(56494259, -), ADediting_546770(56494706, -), ADediting_546771(56494718, -), ADediting_546772(56494773, -), ADediting_546773(56494840, -), ADediting_546774(56494899, -), ADediting_546775(56508708, -), ADediting_546776(56508724, -), ADediting_546777(56508738, -), ADediting_546778(56508761, -), ADediting_546779(56508784, -), ADediting_546780(56508794, -), ADediting_546781(56508811, -), ADediting_546782(56508844, -), ADediting_546783(56508845, -), ADediting_546784(56508847, -), ADediting_546785(56508848, -), ADediting_546786(56508876, -), ADediting_546787(56508881, -), ADediting_546788(56508899, -), ADediting_546789(56509285, -), ADediting_546790(56509370, -), ADediting_546791(56509380, -), ADediting_546792(56509402, -), ADediting_546793(56509419, -), ADediting_546794(56509425, -), ADediting_546795(56509426, -), ADediting_546796(56509439, -), ADediting_546797(56509440, -), ADediting_546798(56509480, -), ADediting_546799(56509488, -), ADediting_546800(56516529, -), ADediting_546801(56516534, -), ADediting_546802(56516535, -), ADediting_546803(56516576, -), ADediting_546804(56516665, -), ADediting_546805(56517887, -), ADediting_546806(56517912, -), ADediting_546807(56517916, -), ADediting_546808(56517922, -), ADediting_546809(56517957, -), ADediting_546810(56517958, -), ADediting_546811(56517960, -), ADediting_546812(56517968, -), ADediting_546813(56517990, -), ADediting_546814(56518029, -), ADediting_546815(56519074, -), ADediting_546816(56519083, -), ADediting_546817(56519105, -), ADediting_546818(56519114, -), ADediting_546819(56519284, -), ADediting_1543100(56480569, -), ADediting_1543101(56483821, -), ADediting_1543102(56484163, -), ADediting_1543103(56490413, -), ADediting_1543104(56490520, -), ADediting_1624757(56490941, -), ADediting_1624758(56493204, -), ADediting_1624759(56494850, -), ADediting_1624760(56507723, -), ADediting_1624761(56508815, -), ADediting_1624762(56508837, -), ADediting_1624763(56508938, -), ADediting_1624764(56509336, -), ADediting_1624765(56509338, -), ADediting_1624766(56509353, -), ADediting_1624767(56509445, -), ADediting_1624768(56516635, -), |
Top |
RNA editing positional annotations for BBS2 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_546679 | chr16_56479252_- | intronic |
| ADediting_546680 | chr16_56480473_- | intronic |
| ADediting_546681 | chr16_56480478_- | intronic |
| ADediting_546682 | chr16_56480481_- | intronic |
| ADediting_546683 | chr16_56480551_- | intronic |
| ADediting_546684 | chr16_56480555_- | intronic |
| ADediting_546685 | chr16_56480568_- | intronic |
| ADediting_546686 | chr16_56480570_- | intronic |
| ADediting_546687 | chr16_56480573_- | intronic |
| ADediting_546688 | chr16_56480579_- | intronic |
| ADediting_546689 | chr16_56480584_- | intronic |
| ADediting_546690 | chr16_56480647_- | intronic |
| ADediting_546691 | chr16_56483730_- | intronic |
| ADediting_546692 | chr16_56483811_- | intronic |
| ADediting_546693 | chr16_56483824_- | intronic |
| ADediting_546694 | chr16_56483837_- | intronic |
| ADediting_546695 | chr16_56483864_- | intronic |
| ADediting_546696 | chr16_56483878_- | intronic |
| ADediting_546697 | chr16_56483883_- | intronic |
| ADediting_546698 | chr16_56483914_- | intronic |
| ADediting_546699 | chr16_56483951_- | intronic |
| ADediting_546700 | chr16_56483976_- | intronic |
| ADediting_546701 | chr16_56484067_- | intronic |
| ADediting_546702 | chr16_56484118_- | intronic |
| ADediting_546703 | chr16_56484135_- | intronic |
| ADediting_546704 | chr16_56484139_- | intronic |
| ADediting_546705 | chr16_56484145_- | intronic |
| ADediting_546706 | chr16_56484171_- | intronic |
| ADediting_546707 | chr16_56484183_- | intronic |
| ADediting_546708 | chr16_56484185_- | intronic |
| ADediting_546709 | chr16_56484190_- | intronic |
| ADediting_546710 | chr16_56484201_- | intronic |
| ADediting_546711 | chr16_56484202_- | intronic |
| ADediting_546712 | chr16_56484211_- | intronic |
| ADediting_546713 | chr16_56486560_- | intronic |
| ADediting_546714 | chr16_56486785_- | intronic |
| ADediting_546715 | chr16_56486839_- | intronic |
| ADediting_546716 | chr16_56486874_- | intronic |
| ADediting_546717 | chr16_56486887_- | intronic |
| ADediting_546718 | chr16_56486900_- | intronic |
| ADediting_546719 | chr16_56486901_- | intronic |
| ADediting_546720 | chr16_56486923_- | intronic |
| ADediting_546721 | chr16_56486927_- | intronic |
| ADediting_546722 | chr16_56488977_- | intronic |
| ADediting_546723 | chr16_56489000_- | intronic |
| ADediting_546724 | chr16_56489134_- | intronic |
| ADediting_546725 | chr16_56489135_- | intronic |
| ADediting_546726 | chr16_56489136_- | intronic |
| ADediting_546727 | chr16_56489142_- | intronic |
| ADediting_546728 | chr16_56489154_- | intronic |
| ADediting_546729 | chr16_56489159_- | intronic |
| ADediting_546730 | chr16_56489167_- | intronic |
| ADediting_546731 | chr16_56489173_- | intronic |
| ADediting_546732 | chr16_56489219_- | intronic |
| ADediting_546733 | chr16_56490108_- | intronic |
| ADediting_546734 | chr16_56490475_- | intronic |
| ADediting_546735 | chr16_56490478_- | intronic |
| ADediting_546736 | chr16_56490495_- | intronic |
| ADediting_546737 | chr16_56490558_- | intronic |
| ADediting_546738 | chr16_56490565_- | intronic |
| ADediting_546739 | chr16_56490594_- | intronic |
| ADediting_546740 | chr16_56490635_- | intronic |
| ADediting_546741 | chr16_56490858_- | intronic |
| ADediting_546742 | chr16_56490900_- | intronic |
| ADediting_546743 | chr16_56490945_- | intronic |
| ADediting_546744 | chr16_56490956_- | intronic |
| ADediting_546745 | chr16_56491007_- | intronic |
| ADediting_546746 | chr16_56491033_- | intronic |
| ADediting_546747 | chr16_56491034_- | intronic |
| ADediting_546748 | chr16_56493262_- | intronic |
| ADediting_546749 | chr16_56493274_- | intronic |
| ADediting_546750 | chr16_56493291_- | intronic |
| ADediting_546751 | chr16_56493303_- | intronic |
| ADediting_546752 | chr16_56493987_- | intronic |
| ADediting_546753 | chr16_56493988_- | intronic |
| ADediting_546754 | chr16_56494055_- | intronic |
| ADediting_546755 | chr16_56494069_- | intronic |
| ADediting_546756 | chr16_56494083_- | intronic |
| ADediting_546757 | chr16_56494097_- | intronic |
| ADediting_546758 | chr16_56494113_- | intronic |
| ADediting_546759 | chr16_56494167_- | intronic |
| ADediting_546760 | chr16_56494169_- | intronic |
| ADediting_546761 | chr16_56494171_- | intronic |
| ADediting_546762 | chr16_56494181_- | intronic |
| ADediting_546763 | chr16_56494186_- | intronic |
| ADediting_546764 | chr16_56494218_- | intronic |
| ADediting_546765 | chr16_56494235_- | intronic |
| ADediting_546766 | chr16_56494240_- | intronic |
| ADediting_546767 | chr16_56494241_- | intronic |
| ADediting_546768 | chr16_56494254_- | intronic |
| ADediting_546769 | chr16_56494259_- | intronic |
| ADediting_546770 | chr16_56494706_- | intronic |
| ADediting_546771 | chr16_56494718_- | intronic |
| ADediting_546772 | chr16_56494773_- | intronic |
| ADediting_546773 | chr16_56494840_- | intronic |
| ADediting_546774 | chr16_56494899_- | intronic |
| ADediting_546775 | chr16_56508708_- | intronic |
| ADediting_546776 | chr16_56508724_- | intronic |
| ADediting_546777 | chr16_56508738_- | intronic |
| ADediting_546778 | chr16_56508761_- | intronic |
| ADediting_546779 | chr16_56508784_- | intronic |
| ADediting_546780 | chr16_56508794_- | intronic |
| ADediting_546781 | chr16_56508811_- | intronic |
| ADediting_546782 | chr16_56508844_- | intronic |
| ADediting_546783 | chr16_56508845_- | intronic |
| ADediting_546784 | chr16_56508847_- | intronic |
| ADediting_546785 | chr16_56508848_- | intronic |
| ADediting_546786 | chr16_56508876_- | intronic |
| ADediting_546787 | chr16_56508881_- | intronic |
| ADediting_546788 | chr16_56508899_- | intronic |
| ADediting_546789 | chr16_56509285_- | intronic |
| ADediting_546790 | chr16_56509370_- | intronic |
| ADediting_546791 | chr16_56509380_- | intronic |
| ADediting_546792 | chr16_56509402_- | intronic |
| ADediting_546793 | chr16_56509419_- | intronic |
| ADediting_546794 | chr16_56509425_- | intronic |
| ADediting_546795 | chr16_56509426_- | intronic |
| ADediting_546796 | chr16_56509439_- | intronic |
| ADediting_546797 | chr16_56509440_- | intronic |
| ADediting_546798 | chr16_56509480_- | intronic |
| ADediting_546799 | chr16_56509488_- | intronic |
| ADediting_546800 | chr16_56516529_- | intronic |
| ADediting_546801 | chr16_56516534_- | intronic |
| ADediting_546802 | chr16_56516535_- | intronic |
| ADediting_546803 | chr16_56516576_- | intronic |
| ADediting_546804 | chr16_56516665_- | intronic |
| ADediting_546805 | chr16_56517887_- | intronic |
| ADediting_546806 | chr16_56517912_- | intronic |
| ADediting_546807 | chr16_56517916_- | intronic |
| ADediting_546808 | chr16_56517922_- | intronic |
| ADediting_546809 | chr16_56517957_- | intronic |
| ADediting_546810 | chr16_56517958_- | intronic |
| ADediting_546811 | chr16_56517960_- | intronic |
| ADediting_546812 | chr16_56517968_- | intronic |
| ADediting_546813 | chr16_56517990_- | intronic |
| ADediting_546814 | chr16_56518029_- | intronic |
| ADediting_546815 | chr16_56519074_- | intronic |
| ADediting_546816 | chr16_56519083_- | intronic |
| ADediting_546817 | chr16_56519105_- | intronic |
| ADediting_546818 | chr16_56519114_- | intronic |
| ADediting_546819 | chr16_56519284_- | intronic |
| ADediting_1543100 | chr16_56480569_- | intronic |
| ADediting_1543101 | chr16_56483821_- | intronic |
| ADediting_1543102 | chr16_56484163_- | intronic |
| ADediting_1543103 | chr16_56490413_- | intronic |
| ADediting_1543104 | chr16_56490520_- | intronic |
| ADediting_1624757 | chr16_56490941_- | intronic |
| ADediting_1624758 | chr16_56493204_- | intronic |
| ADediting_1624759 | chr16_56494850_- | intronic |
| ADediting_1624760 | chr16_56507723_- | intronic |
| ADediting_1624761 | chr16_56508815_- | intronic |
| ADediting_1624762 | chr16_56508837_- | intronic |
| ADediting_1624763 | chr16_56508938_- | intronic |
| ADediting_1624764 | chr16_56509336_- | intronic |
| ADediting_1624765 | chr16_56509338_- | intronic |
| ADediting_1624766 | chr16_56509353_- | intronic |
| ADediting_1624767 | chr16_56509445_- | intronic |
| ADediting_1624768 | chr16_56516635_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_546679 | chr16_56479252_- | SINE | Alu | Name=AluSx |
| ADediting_546680 | chr16_56480473_- | SINE | Alu | Name=AluSx1 |
| ADediting_546681 | chr16_56480478_- | SINE | Alu | Name=AluSx1 |
| ADediting_546682 | chr16_56480481_- | SINE | Alu | Name=AluSx1 |
| ADediting_546683 | chr16_56480551_- | SINE | Alu | Name=AluSx1 |
| ADediting_546684 | chr16_56480555_- | SINE | Alu | Name=AluSx1 |
| ADediting_546685 | chr16_56480568_- | SINE | Alu | Name=AluSx1 |
| ADediting_546686 | chr16_56480570_- | SINE | Alu | Name=AluSx1 |
| ADediting_546687 | chr16_56480573_- | SINE | Alu | Name=AluSx1 |
| ADediting_546688 | chr16_56480579_- | SINE | Alu | Name=AluSx1 |
| ADediting_546689 | chr16_56480584_- | SINE | Alu | Name=AluSx1 |
| ADediting_546690 | chr16_56480647_- | SINE | Alu | Name=AluSx1 |
| ADediting_546691 | chr16_56483730_- | SINE | Alu | Name=AluSq2 |
| ADediting_546692 | chr16_56483811_- | SINE | Alu | Name=AluSq2 |
| ADediting_546693 | chr16_56483824_- | SINE | Alu | Name=AluSq2 |
| ADediting_546694 | chr16_56483837_- | SINE | Alu | Name=AluSq2 |
| ADediting_546695 | chr16_56483864_- | SINE | Alu | Name=AluSq2 |
| ADediting_546696 | chr16_56483878_- | SINE | Alu | Name=AluSq2 |
| ADediting_546697 | chr16_56483883_- | SINE | Alu | Name=AluSq2 |
| ADediting_546698 | chr16_56483914_- | SINE | Alu | Name=AluSq2 |
| ADediting_546699 | chr16_56483951_- | SINE | Alu | Name=AluSq2 |
| ADediting_546700 | chr16_56483976_- | SINE | Alu | Name=AluSq2 |
| ADediting_546701 | chr16_56484067_- | SINE | Alu | Name=AluSc8 |
| ADediting_546702 | chr16_56484118_- | SINE | Alu | Name=AluSc8 |
| ADediting_546703 | chr16_56484135_- | SINE | Alu | Name=AluSc8 |
| ADediting_546704 | chr16_56484139_- | SINE | Alu | Name=AluSc8 |
| ADediting_546705 | chr16_56484145_- | SINE | Alu | Name=AluSc8 |
| ADediting_546706 | chr16_56484171_- | SINE | Alu | Name=AluSc8 |
| ADediting_546707 | chr16_56484183_- | SINE | Alu | Name=AluSc8 |
| ADediting_546708 | chr16_56484185_- | SINE | Alu | Name=AluSc8 |
| ADediting_546709 | chr16_56484190_- | SINE | Alu | Name=AluSc8 |
| ADediting_546710 | chr16_56484201_- | SINE | Alu | Name=AluSc8 |
| ADediting_546711 | chr16_56484202_- | SINE | Alu | Name=AluSc8 |
| ADediting_546712 | chr16_56484211_- | SINE | Alu | Name=AluSc8 |
| ADediting_546713 | chr16_56486560_- | LINE | L1 | Name=L1ME1 |
| ADediting_546714 | chr16_56486785_- | SINE | Alu | Name=AluSq2 |
| ADediting_546715 | chr16_56486839_- | SINE | Alu | Name=AluSq2 |
| ADediting_546716 | chr16_56486874_- | SINE | Alu | Name=AluSq2 |
| ADediting_546717 | chr16_56486887_- | SINE | Alu | Name=AluSq2 |
| ADediting_546718 | chr16_56486900_- | SINE | Alu | Name=AluSq2 |
| ADediting_546719 | chr16_56486901_- | SINE | Alu | Name=AluSq2 |
| ADediting_546720 | chr16_56486923_- | SINE | Alu | Name=AluSq2 |
| ADediting_546721 | chr16_56486927_- | SINE | Alu | Name=AluSq2 |
| ADediting_546722 | chr16_56488977_- | SINE | Alu | Name=FLAM_C |
| ADediting_546723 | chr16_56489000_- | SINE | Alu | Name=FLAM_C |
| ADediting_546724 | chr16_56489134_- | SINE | Alu | Name=AluJb |
| ADediting_546725 | chr16_56489135_- | SINE | Alu | Name=AluJb |
| ADediting_546726 | chr16_56489136_- | SINE | Alu | Name=AluJb |
| ADediting_546727 | chr16_56489142_- | SINE | Alu | Name=AluJb |
| ADediting_546728 | chr16_56489154_- | SINE | Alu | Name=AluJb |
| ADediting_546729 | chr16_56489159_- | SINE | Alu | Name=AluJb |
| ADediting_546730 | chr16_56489167_- | SINE | Alu | Name=AluJb |
| ADediting_546731 | chr16_56489173_- | SINE | Alu | Name=AluJb |
| ADediting_546732 | chr16_56489219_- | SINE | Alu | Name=AluJb |
| ADediting_546733 | chr16_56490108_- | SINE | Alu | Name=AluJo |
| ADediting_546734 | chr16_56490475_- | SINE | Alu | Name=AluSx1 |
| ADediting_546735 | chr16_56490478_- | SINE | Alu | Name=AluSx1 |
| ADediting_546736 | chr16_56490495_- | SINE | Alu | Name=AluSx1 |
| ADediting_546737 | chr16_56490558_- | SINE | Alu | Name=AluSx1 |
| ADediting_546738 | chr16_56490565_- | SINE | Alu | Name=AluSx1 |
| ADediting_546739 | chr16_56490594_- | SINE | Alu | Name=AluSx1 |
| ADediting_546740 | chr16_56490635_- | SINE | Alu | Name=AluSx1 |
| ADediting_546741 | chr16_56490858_- | SINE | Alu | Name=AluY |
| ADediting_546742 | chr16_56490900_- | SINE | Alu | Name=AluY |
| ADediting_546743 | chr16_56490945_- | SINE | Alu | Name=AluY |
| ADediting_546744 | chr16_56490956_- | SINE | Alu | Name=AluY |
| ADediting_546745 | chr16_56491007_- | SINE | Alu | Name=AluY |
| ADediting_546746 | chr16_56491033_- | SINE | Alu | Name=AluY |
| ADediting_546747 | chr16_56491034_- | SINE | Alu | Name=AluY |
| ADediting_546748 | chr16_56493262_- | SINE | Alu | Name=AluJb |
| ADediting_546749 | chr16_56493274_- | SINE | Alu | Name=AluJb |
| ADediting_546750 | chr16_56493291_- | SINE | Alu | Name=AluJb |
| ADediting_546751 | chr16_56493303_- | SINE | Alu | Name=AluJb |
| ADediting_546752 | chr16_56493987_- | SINE | Alu | Name=AluJo |
| ADediting_546753 | chr16_56493988_- | SINE | Alu | Name=AluJo |
| ADediting_546754 | chr16_56494055_- | SINE | Alu | Name=AluJo |
| ADediting_546755 | chr16_56494069_- | SINE | Alu | Name=AluJo |
| ADediting_546756 | chr16_56494083_- | SINE | Alu | Name=AluJo |
| ADediting_546757 | chr16_56494097_- | SINE | Alu | Name=AluJo |
| ADediting_546758 | chr16_56494113_- | SINE | Alu | Name=AluJo |
| ADediting_546759 | chr16_56494167_- | SINE | Alu | Name=AluJo |
| ADediting_546760 | chr16_56494169_- | SINE | Alu | Name=AluJo |
| ADediting_546761 | chr16_56494171_- | SINE | Alu | Name=AluJo |
| ADediting_546762 | chr16_56494181_- | SINE | Alu | Name=AluJo |
| ADediting_546763 | chr16_56494186_- | SINE | Alu | Name=AluJo |
| ADediting_546764 | chr16_56494218_- | SINE | Alu | Name=AluJo |
| ADediting_546765 | chr16_56494235_- | SINE | Alu | Name=AluJo |
| ADediting_546766 | chr16_56494240_- | SINE | Alu | Name=AluJo |
| ADediting_546767 | chr16_56494241_- | SINE | Alu | Name=AluJo |
| ADediting_546768 | chr16_56494254_- | SINE | Alu | Name=AluJo |
| ADediting_546769 | chr16_56494259_- | SINE | Alu | Name=AluJo |
| ADediting_546770 | chr16_56494706_- | SINE | Alu | Name=AluY |
| ADediting_546771 | chr16_56494718_- | SINE | Alu | Name=AluY |
| ADediting_546772 | chr16_56494773_- | SINE | Alu | Name=AluY |
| ADediting_546773 | chr16_56494840_- | SINE | Alu | Name=AluY |
| ADediting_546774 | chr16_56494899_- | SINE | Alu | Name=AluY |
| ADediting_546775 | chr16_56508708_- | SINE | Alu | Name=AluJr |
| ADediting_546776 | chr16_56508724_- | SINE | Alu | Name=AluJr |
| ADediting_546777 | chr16_56508738_- | SINE | Alu | Name=AluJr |
| ADediting_546778 | chr16_56508761_- | SINE | Alu | Name=AluJr |
| ADediting_546779 | chr16_56508784_- | SINE | Alu | Name=AluJr |
| ADediting_546780 | chr16_56508794_- | SINE | Alu | Name=AluJr |
| ADediting_546781 | chr16_56508811_- | SINE | Alu | Name=AluJr |
| ADediting_546782 | chr16_56508844_- | SINE | Alu | Name=AluJr |
| ADediting_546783 | chr16_56508845_- | SINE | Alu | Name=AluJr |
| ADediting_546784 | chr16_56508847_- | SINE | Alu | Name=AluJr |
| ADediting_546785 | chr16_56508848_- | SINE | Alu | Name=AluJr |
| ADediting_546786 | chr16_56508876_- | SINE | Alu | Name=AluJr |
| ADediting_546787 | chr16_56508881_- | SINE | Alu | Name=AluJr |
| ADediting_546788 | chr16_56508899_- | SINE | Alu | Name=AluJr |
| ADediting_546789 | chr16_56509285_- | SINE | Alu | Name=AluSz |
| ADediting_546790 | chr16_56509370_- | SINE | Alu | Name=AluSz |
| ADediting_546791 | chr16_56509380_- | SINE | Alu | Name=AluSz |
| ADediting_546792 | chr16_56509402_- | SINE | Alu | Name=AluSz |
| ADediting_546793 | chr16_56509419_- | SINE | Alu | Name=AluSz |
| ADediting_546794 | chr16_56509425_- | SINE | Alu | Name=AluSz |
| ADediting_546795 | chr16_56509426_- | SINE | Alu | Name=AluSz |
| ADediting_546796 | chr16_56509439_- | SINE | Alu | Name=AluSz |
| ADediting_546797 | chr16_56509440_- | SINE | Alu | Name=AluSz |
| ADediting_546798 | chr16_56509480_- | SINE | Alu | Name=AluSz |
| ADediting_546799 | chr16_56509488_- | SINE | Alu | Name=AluSz |
| ADediting_546800 | chr16_56516529_- | SINE | Alu | Name=AluSx |
| ADediting_546801 | chr16_56516534_- | SINE | Alu | Name=AluSx |
| ADediting_546802 | chr16_56516535_- | SINE | Alu | Name=AluSx |
| ADediting_546803 | chr16_56516576_- | SINE | Alu | Name=AluSx |
| ADediting_546804 | chr16_56516665_- | SINE | Alu | Name=AluSx |
| ADediting_546805 | chr16_56517887_- | SINE | Alu | Name=AluSx1 |
| ADediting_546806 | chr16_56517912_- | SINE | Alu | Name=AluSx1 |
| ADediting_546807 | chr16_56517916_- | SINE | Alu | Name=AluSx1 |
| ADediting_546808 | chr16_56517922_- | SINE | Alu | Name=AluSx1 |
| ADediting_546809 | chr16_56517957_- | SINE | Alu | Name=AluSx1 |
| ADediting_546810 | chr16_56517958_- | SINE | Alu | Name=AluSx1 |
| ADediting_546811 | chr16_56517960_- | SINE | Alu | Name=AluSx1 |
| ADediting_546812 | chr16_56517968_- | SINE | Alu | Name=AluSx1 |
| ADediting_546813 | chr16_56517990_- | SINE | Alu | Name=AluSx1 |
| ADediting_546814 | chr16_56518029_- | SINE | Alu | Name=AluSx1 |
| ADediting_546815 | chr16_56519074_- | SINE | Alu | Name=AluSx1 |
| ADediting_546816 | chr16_56519083_- | SINE | Alu | Name=AluSx1 |
| ADediting_546817 | chr16_56519105_- | SINE | Alu | Name=AluSx1 |
| ADediting_546818 | chr16_56519114_- | SINE | Alu | Name=AluSx1 |
| ADediting_546819 | chr16_56519284_- | SINE | Alu | Name=AluSx1 |
| ADediting_1543100 | chr16_56480569_- | SINE | Alu | Name=AluSx1 |
| ADediting_1543101 | chr16_56483821_- | SINE | Alu | Name=AluSq2 |
| ADediting_1543102 | chr16_56484163_- | SINE | Alu | Name=AluSc8 |
| ADediting_1543103 | chr16_56490413_- | SINE | Alu | Name=AluSx1 |
| ADediting_1543104 | chr16_56490520_- | SINE | Alu | Name=AluSx1 |
| ADediting_1624757 | chr16_56490941_- | SINE | Alu | Name=AluY |
| ADediting_1624758 | chr16_56493204_- | SINE | Alu | Name=AluJb |
| ADediting_1624759 | chr16_56494850_- | SINE | Alu | Name=AluY |
| ADediting_1624760 | chr16_56507723_- | SINE | Alu | Name=AluSq2 |
| ADediting_1624761 | chr16_56508815_- | SINE | Alu | Name=AluJr |
| ADediting_1624762 | chr16_56508837_- | SINE | Alu | Name=AluJr |
| ADediting_1624763 | chr16_56508938_- | SINE | Alu | Name=AluJr |
| ADediting_1624764 | chr16_56509336_- | SINE | Alu | Name=AluSz |
| ADediting_1624765 | chr16_56509338_- | SINE | Alu | Name=AluSz |
| ADediting_1624766 | chr16_56509353_- | SINE | Alu | Name=AluSz |
| ADediting_1624767 | chr16_56509445_- | SINE | Alu | Name=AluSz |
| ADediting_1624768 | chr16_56516635_- | SINE | Alu | Name=AluSx |
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RNA A-to-I editing events in the alternative splicing sites for BBS2 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| A3SS | ADediting_546798 | chr16_56509480_- | 56509472:56509494 | 3ss | 6i | AGTTTTACTCCATCACCCAGGCT | 3.88 | AGTTTTACTCCATCGCCCAGGCT | 3.32 |
| A3SS | ADediting_546799 | chr16_56509488_- | 56509472:56509494 | 3ss | 14i | AGTTTTACTCCATCACCCAGGCT | 3.88 | AGTTTTGCTCCATCACCCAGGCT | 4.89 |
| ES | ADediting_546798 | chr16_56509480_- | 56509472:56509494 | 3ss | 6i | AGTTTTACTCCATCACCCAGGCT | 3.88 | AGTTTTACTCCATCGCCCAGGCT | 3.32 |
| ES | ADediting_546799 | chr16_56509488_- | 56509472:56509494 | 3ss | 14i | AGTTTTACTCCATCACCCAGGCT | 3.88 | AGTTTTGCTCCATCACCCAGGCT | 4.89 |
| ES | ADediting_546799 | chr16_56509488_- | 56509472:56509494 | 3ss | 14i | AGTTTTACTCCATCACCCAGGCT | 3.88 | AGTTTTGCTCCATCACCCAGGCT | 4.89 |
| ES | ADediting_1624766 | chr16_56509353_- | 56509351:56509359 | 5ss | 4i | TGGGTAATT | 6.19 | TGGGTAGTT | 1.13 |
| ES | ADediting_1624766 | chr16_56509353_- | 56509351:56509359 | 5ss | 4i | TGGGTAATT | 6.19 | TGGGTAGTT | 1.13 |
| ES | ADediting_1624766 | chr16_56509353_- | 56509351:56509359 | 5ss | 4i | TGGGTAATT | 6.19 | TGGGTAGTT | 1.13 |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for BBS2 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for BBS2 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for BBS2 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_843620 | chr2_207754818_+ | ENSG00000125124.12 | ENST00000245157.10 | BBS2-201 | hsa-miR-4775 | chr16 | 56484359 | 56484365 | 7mer-m8 | 56484358 | 56484378 | 158 | -12.14 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000125124.12 | ENST00000568104.5 | BBS2-218 | hsa-miR-4775 | chr16 | 56484359 | 56484365 | 7mer-m8 | 56484358 | 56484378 | 158 | -12.14 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000125124.12 | ENST00000564123.6 | BBS2-208 | hsa-miR-5688 | chr16 | 56466923 | 56466929 | 7mer-m8 | 56466922 | 56466943 | 140 | -8.62 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000125124.12 | ENST00000564123.6 | BBS2-208 | hsa-miR-589-3p | chr16 | 56466873 | 56466879 | 7mer-m8 | 56466872 | 56466895 | 143 | -20.38 |
| ADediting_1643790 | chr3_121049689_+ | ENSG00000125124.12 | ENST00000245157.10 | BBS2-201 | hsa-miR-5682 | chr16 | 56484661 | 56484668 | 8mer-1a | 56484661 | 56484680 | 144 | -14.5 |
| ADediting_1643790 | chr3_121049689_+ | ENSG00000125124.12 | ENST00000568104.5 | BBS2-218 | hsa-miR-5682 | chr16 | 56484661 | 56484668 | 8mer-1a | 56484661 | 56484680 | 144 | -14.5 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for BBS2 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for BBS2 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_546687 | chr16_56480573_- | 0.0220133243754828 | 0.186901629205356 | 0.0235816246095724 | 0.184795766275643 | 3.6170169265858e-05 | 0.33050536830946 |
| TCX | ADediting_546705 | chr16_56484145_- | 0.300440277356325 | 0.0851058266134974 | 0.686752016531555 | 0.0331952061603481 | 0.000156993329860523 | 0.303827874119458 |
| DLPFC | ADediting_546746 | chr16_56491033_- | 0.078808278042484 | 0.0999810388916564 | 0.645173608785484 | -0.0262549118248476 | 9.70117890520815e-18 | 0.461284442046303 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 5.74244494725125e-23 | 0.5209716271142 | 1.44628580133531e-23 | 0.527116886160884 | 1.75298799450809e-12 | 0.386465159205957 |
| AC | 1.3412070668943e-66 | 0.836048992381424 | 3.03147078043832e-42 | 0.7262064333394 | 9.85342363945866e-21 | 0.54489103954303 |
| PCC | 7.66685250473959e-13 | 0.488375790322586 | 3.84688422629995e-10 | 0.433247075158134 | 2.49153347652299e-08 | 0.389801521930587 |
| CER | 3.21616207121496e-06 | 0.369734225665424 | 0.0471270427960632 | 0.162368418887748 | 1.88082413853142e-06 | 0.377770260616077 |
| TCX | 9.29220778762595e-08 | 0.419261358248638 | 0.956321652497408 | 0.00450965955379621 | 3.47792832433709e-15 | 0.58568897594639 |
| FP | 7.04558618575305e-27 | 0.693752829687027 | 8.7622005318647e-26 | 0.682872042665795 | 1.18089835429899e-09 | 0.435980456314968 |
| IFG | 1.51158093809892e-06 | 0.80096755271441 | 0.000656703124440364 | 0.634566094400352 | 0.000423792226455227 | 0.651084347114222 |
| PG | 1.34066258378694e-49 | 0.834918344954826 | 1.01956945194967e-22 | 0.638811683821958 | 0.0292534041876324 | 0.159897372480798 |
| STG | 1.17176480782446e-16 | 0.754432923639944 | 9.35812694729323e-07 | 0.505522659440003 | 0.000136156412152223 | 0.404388089775223 |
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Relation with AD stages for BBS2 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| TCX | 1.42574728849857e-09 | 0.54593789044725 |
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RelatedDrugs for BBS2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for BBS2 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| BBS2 | C2936863 | Bardet-Biedl syndrome 2 (disorder) | 7 | CTD_human;UNIPROT |
| BBS2 | C4225281 | RETINITIS PIGMENTOSA 74 | 1 | CTD_human;UNIPROT |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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