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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for PEX2 |
 Gene summary |
| Gene information | Gene symbol | PEX2 | Gene ID | 5828 |
| Gene name | peroxisomal biogenesis factor 2 | |
| Synonyms | PAF1|PBD5A|PBD5B|PMP3|PMP35|PXMP3|RNF72|ZWS3 | |
| Cytomap | 8q21.13 | |
| Type of gene | protein-coding | |
| Description | peroxisome biogenesis factor 235 kDa peroxisomal membrane proteinRING finger protein 72peroxisomal membrane protein 3, 35kDaperoxisome assembly factor 1 | |
| Modification date | 20200313 | |
| UniProtAcc | P28328, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for PEX2 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_1421877(76981214, -), ADediting_1421878(76982567, -), ADediting_1421879(76982568, -), ADediting_1421880(76982577, -), ADediting_1421881(76982618, -), ADediting_1421882(76982622, -), ADediting_1421883(76982643, -), ADediting_1421884(76982646, -), ADediting_1421885(76982697, -), ADediting_1421886(76982722, -), ADediting_1421887(76982723, -), ADediting_1421888(76982726, -), ADediting_1421889(76982746, -), ADediting_1591497(76981589, -), ADediting_1591498(76982555, -), |
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RNA editing positional annotations for PEX2 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_1421877 | chr8_76981214_- | UTR3 |
| ADediting_1421878 | chr8_76982567_- | UTR3 |
| ADediting_1421879 | chr8_76982568_- | UTR3 |
| ADediting_1421880 | chr8_76982577_- | UTR3 |
| ADediting_1421881 | chr8_76982618_- | UTR3 |
| ADediting_1421882 | chr8_76982622_- | UTR3 |
| ADediting_1421883 | chr8_76982643_- | UTR3 |
| ADediting_1421884 | chr8_76982646_- | UTR3 |
| ADediting_1421885 | chr8_76982697_- | UTR3 |
| ADediting_1421886 | chr8_76982722_- | UTR3 |
| ADediting_1421887 | chr8_76982723_- | UTR3 |
| ADediting_1421888 | chr8_76982726_- | UTR3 |
| ADediting_1421889 | chr8_76982746_- | UTR3 |
| ADediting_1591497 | chr8_76981589_- | UTR3 |
| ADediting_1591498 | chr8_76982555_- | UTR3 |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_1421877 | chr8_76981214_- | SINE | Alu | Name=AluJb |
| ADediting_1421878 | chr8_76982567_- | SINE | Alu | Name=AluSc8 |
| ADediting_1421879 | chr8_76982568_- | SINE | Alu | Name=AluSc8 |
| ADediting_1421880 | chr8_76982577_- | SINE | Alu | Name=AluSc8 |
| ADediting_1421881 | chr8_76982618_- | SINE | Alu | Name=AluSc8 |
| ADediting_1421882 | chr8_76982622_- | SINE | Alu | Name=AluSc8 |
| ADediting_1421883 | chr8_76982643_- | SINE | Alu | Name=AluSc8 |
| ADediting_1421884 | chr8_76982646_- | SINE | Alu | Name=AluSc8 |
| ADediting_1421885 | chr8_76982697_- | SINE | Alu | Name=AluSc8 |
| ADediting_1421886 | chr8_76982722_- | SINE | Alu | Name=AluSc8 |
| ADediting_1421887 | chr8_76982723_- | SINE | Alu | Name=AluSc8 |
| ADediting_1421888 | chr8_76982726_- | SINE | Alu | Name=AluSc8 |
| ADediting_1421889 | chr8_76982746_- | SINE | Alu | Name=AluSc8 |
| ADediting_1591497 | chr8_76981589_- | SINE | Alu | Name=AluJo |
| ADediting_1591498 | chr8_76982555_- | SINE | Alu | Name=AluSc8 |
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RNA A-to-I editing events in the alternative splicing sites for PEX2 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for PEX2 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
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| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for PEX2 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for PEX2 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1421878 | chr8_76982567_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-3189-3p | chr8 | 76982566 | 76982572 | 7mer-m8 | 76982565 | 76982588 | 157 | -27.21 |
| ADediting_1421878 | chr8_76982567_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-6813-3p | chr8 | 76982565 | 76982571 | 7mer-m8 | 76982564 | 76982584 | 140 | -12.88 |
| ADediting_1421879 | chr8_76982568_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-326 | chr8 | 76982566 | 76982572 | 7mer-m8 | 76982565 | 76982584 | 140 | -14.45 |
| ADediting_1421879 | chr8_76982568_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-330-5p | chr8 | 76982566 | 76982572 | 7mer-m8 | 76982565 | 76982586 | 148 | -23.39 |
| ADediting_1421879 | chr8_76982568_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-4314 | chr8 | 76982567 | 76982573 | 7mer-m8 | 76982566 | 76982583 | 140 | -19.43 |
| ADediting_1421879 | chr8_76982568_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-514a-5p | chr8 | 76982565 | 76982571 | 7mer-m8 | 76982564 | 76982587 | 155 | -21.45 |
| ADediting_1421880 | chr8_76982577_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-6089 | chr8 | 76982572 | 76982578 | 7mer-m8 | 76982571 | 76982593 | 156 | -34.32 |
| ADediting_1421882 | chr8_76982622_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-3190-5p | chr8 | 76982617 | 76982623 | 7mer-m8 | 76982616 | 76982634 | 148 | -20.6 |
| ADediting_1421882 | chr8_76982622_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-548s | chr8 | 76982618 | 76982624 | 7mer-m8 | 76982617 | 76982639 | 149 | -16.48 |
| ADediting_1421885 | chr8_76982697_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-4691-3p | chr8 | 76982693 | 76982699 | 7mer-m8 | 76982692 | 76982719 | 150 | -26.36 |
| ADediting_1421886 | chr8_76982722_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-146a-5p | chr8 | 76982717 | 76982723 | 7mer-m8 | 76982716 | 76982738 | 147 | -21.66 |
| ADediting_1421886 | chr8_76982722_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-146b-5p | chr8 | 76982717 | 76982723 | 7mer-m8 | 76982716 | 76982742 | 152 | -20.63 |
| ADediting_1421886 | chr8_76982722_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-7153-5p | chr8 | 76982717 | 76982723 | 7mer-m8 | 76982716 | 76982739 | 148 | -22.32 |
| ADediting_1421889 | chr8_76982746_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-17-3p | chr8 | 76982746 | 76982752 | 7mer-m8 | 76982745 | 76982767 | 153 | -18.76 |
| ADediting_1591497 | chr8_76981589_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-4252 | chr8 | 76981585 | 76981591 | 7mer-m8 | 76981584 | 76981603 | 160 | -25.3 |
| ADediting_1591497 | chr8_76981589_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-5008-3p | chr8 | 76981589 | 76981595 | 7mer-m8 | 76981588 | 76981605 | 146 | -17.64 |
| ADediting_1591497 | chr8_76981589_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-7157-3p | chr8 | 76981589 | 76981595 | 7mer-m8 | 76981588 | 76981608 | 146 | -14.66 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1421879 | chr8_76982568_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-887-5p | chr8 | 76982567 | 76982574 | 8mer-1a | 76982567 | 76982586 | 143 | -15.14 |
| ADediting_1421880 | chr8_76982577_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-4478 | chr8 | 76982573 | 76982579 | 7mer-m8 | 76982572 | 76982587 | 145 | -20.53 |
| ADediting_1421881 | chr8_76982618_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-4794 | chr8 | 76982617 | 76982623 | 7mer-m8 | 76982616 | 76982637 | 152 | -19.2 |
| ADediting_1421881 | chr8_76982618_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-664a-5p | chr8 | 76982617 | 76982623 | 7mer-m8 | 76982616 | 76982638 | 148 | -14.15 |
| ADediting_1421882 | chr8_76982622_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-4794 | chr8 | 76982617 | 76982623 | 7mer-m8 | 76982616 | 76982637 | 152 | -19.2 |
| ADediting_1421882 | chr8_76982622_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-664a-5p | chr8 | 76982617 | 76982623 | 7mer-m8 | 76982616 | 76982638 | 148 | -14.15 |
| ADediting_1421883 | chr8_76982643_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-3675-3p | chr8 | 76982638 | 76982644 | 7mer-m8 | 76982637 | 76982658 | 145 | -12.58 |
| ADediting_1421885 | chr8_76982697_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-5690 | chr8 | 76982693 | 76982699 | 7mer-m8 | 76982692 | 76982712 | 145 | -16.75 |
| ADediting_1421886 | chr8_76982722_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-219b-3p | chr8 | 76982719 | 76982725 | 7mer-m8 | 76982718 | 76982738 | 153 | -15.53 |
| ADediting_1421886 | chr8_76982722_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-302f | chr8 | 76982720 | 76982726 | 7mer-m8 | 76982719 | 76982735 | 145 | -8.09 |
| ADediting_1421887 | chr8_76982723_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-219b-3p | chr8 | 76982719 | 76982725 | 7mer-m8 | 76982718 | 76982738 | 153 | -15.53 |
| ADediting_1421887 | chr8_76982723_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-302f | chr8 | 76982720 | 76982726 | 7mer-m8 | 76982719 | 76982735 | 145 | -8.09 |
| ADediting_1421889 | chr8_76982746_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-6516-5p | chr8 | 76982746 | 76982752 | 7mer-m8 | 76982745 | 76982767 | 152 | -16.77 |
| ADediting_1591497 | chr8_76981589_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-4289 | chr8 | 76981587 | 76981593 | 7mer-m8 | 76981586 | 76981604 | 153 | -15.56 |
| ADediting_1591498 | chr8_76982555_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-3686 | chr8 | 76982551 | 76982557 | 7mer-m8 | 76982550 | 76982571 | 140 | -11.18 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337757 | chr7_5495852_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-589-3p | chr8 | 76982790 | 76982796 | 7mer-m8 | 76982789 | 76982813 | 158 | -22.45 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-4775 | chr8 | 76981750 | 76981757 | 8mer-1a | 76981750 | 76981771 | 158 | -11.06 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-4775 | chr8 | 76981952 | 76981959 | 8mer-1a | 76981952 | 76981975 | 153 | -10.42 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337758 | chr7_5495892_- | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-589-5p | chr8 | 76980994 | 76981000 | 7mer-m8 | 76980993 | 76981012 | 152 | -20.32 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000164751.15 | ENST00000357039.9 | PEX2-201 | hsa-miR-4775 | chr8 | 76981662 | 76981668 | 7mer-m8 | 76981661 | 76981682 | 145 | -2 |
| Differentially expressed gene-miRNA network |
| Differentially expressed mRNA-miRNA network |
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Top |
The effects of the RNA editing to the stability of the RNA structures for PEX2 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000357039.9 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_1421877 | ENST00000357039.9 | chr8_76981214_- | 3213 | -1184.40 | -1182.80 | -1205.60 |
| ADediting_1591497 | ENST00000357039.9 | chr8_76981589_- | 2838 | -1188.40 | -1182.80 | -1205.60 |
| ADediting_1591498 | ENST00000357039.9 | chr8_76982555_- | 1872 | -1184.30 | -1182.80 | -1205.60 |
| ADediting_1421878 | ENST00000357039.9 | chr8_76982567_- | 1860 | -1184.30 | -1182.80 | -1205.60 |
| ADediting_1421879 | ENST00000357039.9 | chr8_76982568_- | 1859 | -1184.40 | -1182.80 | -1205.60 |
| ADediting_1421880 | ENST00000357039.9 | chr8_76982577_- | 1850 | -1182.10 | -1182.80 | -1205.60 |
| ADediting_1421881 | ENST00000357039.9 | chr8_76982618_- | 1809 | -1183.60 | -1182.80 | -1205.60 |
| ADediting_1421882 | ENST00000357039.9 | chr8_76982622_- | 1805 | -1187.30 | -1182.80 | -1205.60 |
| ADediting_1421883 | ENST00000357039.9 | chr8_76982643_- | 1784 | -1184.00 | -1182.80 | -1205.60 |
| ADediting_1421884 | ENST00000357039.9 | chr8_76982646_- | 1781 | -1184.60 | -1182.80 | -1205.60 |
| ADediting_1421885 | ENST00000357039.9 | chr8_76982697_- | 1730 | -1186.00 | -1182.80 | -1205.60 |
| ADediting_1421886 | ENST00000357039.9 | chr8_76982722_- | 1705 | -1186.30 | -1182.80 | -1205.60 |
| ADediting_1421887 | ENST00000357039.9 | chr8_76982723_- | 1704 | -1182.80 | -1182.80 | -1205.60 |
| ADediting_1421888 | ENST00000357039.9 | chr8_76982726_- | 1701 | -1185.80 | -1182.80 | -1205.60 |
| ADediting_1421889 | ENST00000357039.9 | chr8_76982746_- | 1681 | -1183.60 | -1182.80 | -1205.60 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
Top |
Relation with ADAR for PEX2 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_1421880 | chr8_76982577_- | 0.000678729722770137 | 0.274398326864006 | 9.74020253480564e-05 | 0.31278191634947 | 0.0194229408763316 | 0.190681445129825 |
| CER | ADediting_1421881 | chr8_76982618_- | 0.00678940271818851 | 0.22014893559405 | 7.21979128831025e-08 | 0.422499947057603 | 0.157013387737385 | 0.116129754722608 |
| CER | ADediting_1421882 | chr8_76982622_- | 0.00282147540235353 | 0.242234534919498 | 1.05084617867738e-06 | 0.386254040146596 | 0.10853966261235 | 0.131561073218434 |
| CER | ADediting_1421889 | chr8_76982746_- | 0.0224216329359188 | 0.186341241035699 | 6.7565869065172e-05 | 0.319454718650746 | 0.00209547608079953 | 0.249290904760674 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 4.39120779341651e-21 | 0.500788630474335 | 1.16155150927752e-09 | 0.336839434031732 | 4.2067064942696e-05 | 0.230420158698647 |
| AC | 6.63886396337806e-48 | 0.757878807744095 | 3.89336213102065e-26 | 0.602926269231234 | 1.38909023007753e-24 | 0.587401116474914 |
| PCC | 2.29625663478248e-10 | 0.43821633857435 | 1.13537174694983e-08 | 0.39847809861885 | 0.000159235937749254 | 0.269919345146743 |
| CER | 6.24474151013374e-25 | 0.71665966951364 | 5.14269006602057e-09 | 0.454512865652537 | 4.24566860914583e-09 | 0.456711906316712 |
| TCX | 1.06779308870428e-11 | 0.518545491717581 | 0.757597704788102 | 0.02540858719671 | 2.92332284754936e-13 | 0.550498562481451 |
| FP | 1.47250277905343e-12 | 0.49825522654604 | 3.61540102474294e-13 | 0.50987625514782 | 0.00642764121068377 | 0.203548239813114 |
| PG | 2.79568905875786e-51 | 0.842341782635561 | 2.19879408975179e-17 | 0.569530809643135 | 0.329784132073367 | 0.0718493401207214 |
| STG | 1.82563243611044e-15 | 0.734583426849912 | 3.82833081486635e-09 | 0.588845351735 | 0.0197867775379232 | 0.253886681449282 |
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Relation with AD stages for PEX2 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_1421882 | chr8_76982622_- | 8.15064847129555e-05 | 0.369886537590384 |
| IFG | ADediting_1421882 | chr8_76982622_- | 0.00679078035338057 | 0.527024363859863 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 0.000133458227772581 | 0.359399986360764 |
| TCX | 1.99256511383149e-08 | 0.512228853335936 |
| IFG | 0.0242891808127566 | -0.449185595620075 |
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RelatedDrugs for PEX2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PEX2 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| PEX2 | C1832200 | Peroxisome biogenesis disorders | 2 | CTD_human |
| PEX2 | C0043459 | Zellweger Syndrome | 1 | CTD_human;ORPHANET |
| PEX2 | C0282527 | Infantile Refsum Disease (disorder) | 1 | CTD_human;ORPHANET |
| PEX2 | C0751594 | Zellweger-Like Syndrome | 1 | CTD_human |
| PEX2 | C3542026 | PEROXISOME BIOGENESIS DISORDER 5B | 1 | CTD_human;UNIPROT |
| PEX2 | C3658299 | Zellweger Spectrum | 1 | CTD_human |
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