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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for ABCD4 |
 Gene summary |
| Gene information | Gene symbol | ABCD4 | Gene ID | 5826 |
| Gene name | ATP binding cassette subfamily D member 4 | |
| Synonyms | ABC41|EST352188|MAHCJ|P70R|P79R|PMP69|PXMP1L | |
| Cytomap | 14q24.3 | |
| Type of gene | protein-coding | |
| Description | ATP-binding cassette sub-family D member 469 kDa peroxisomal ABC-transporterATP-binding cassette, sub-family D (ALD), member 4PMP70-related proteinPXMP1-Lperoxisomal membrane protein 69 | |
| Modification date | 20200313 | |
| UniProtAcc | O14678, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
RNA A-to-I events for ABCD4 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_450900(74288946, -), ADediting_450901(74289000, -), ADediting_450902(74289026, -), ADediting_450903(74289030, -), ADediting_450904(74289043, -), ADediting_450905(74289049, -), ADediting_450906(74290748, -), ADediting_450907(74290752, -), ADediting_450908(74290777, -), ADediting_450909(74290781, -), ADediting_450910(74290782, -), ADediting_450911(74290792, -), ADediting_450912(74290793, -), ADediting_450913(74290821, -), ADediting_450914(74290822, -), ADediting_450915(74290866, -), ADediting_450916(74290872, -), ADediting_450917(74290876, -), ADediting_450918(74290948, -), ADediting_450919(74294058, -), ADediting_450920(74294126, -), ADediting_450921(74295766, -), ADediting_450922(74296789, -), ADediting_450923(74296901, -), ADediting_450924(74297596, -), ADediting_450925(74297611, -), ADediting_450926(74297646, -), ADediting_450927(74297684, -), ADediting_450928(74297691, -), ADediting_450929(74297692, -), ADediting_450930(74297698, -), ADediting_450931(74297873, -), ADediting_450932(74298293, -), ADediting_450933(74298339, -), ADediting_450934(74298340, -), ADediting_450935(74298377, -), ADediting_450936(74298400, -), ADediting_450937(74298444, -), ADediting_450938(74298453, -), ADediting_450939(74298474, -), ADediting_450940(74298529, -), ADediting_450941(74299817, -), ADediting_450942(74299827, -), ADediting_450943(74299845, -), ADediting_450944(74299870, -), ADediting_450945(74299890, -), ADediting_450946(74299895, -), ADediting_450947(74299896, -), ADediting_450948(74299938, -), ADediting_450949(74299941, -), ADediting_450950(74299951, -), ADediting_450951(74299980, -), ADediting_450952(74299981, -), ADediting_450953(74300001, -), ADediting_450954(74300011, -), ADediting_450955(74300016, -), ADediting_450956(74300021, -), ADediting_450957(74300480, -), ADediting_450958(74300505, -), ADediting_450959(74300516, -), ADediting_450960(74300529, -), ADediting_450961(74300545, -), ADediting_450962(74300546, -), ADediting_450963(74300553, -), ADediting_450964(74300955, -), ADediting_450965(74300977, -), ADediting_450966(74300990, -), ADediting_450967(74300991, -), ADediting_450968(74301017, -), ADediting_450969(74301026, -), ADediting_450970(74301030, -), ADediting_450971(74301031, -), ADediting_450972(74301032, -), ADediting_450973(74301035, -), ADediting_450974(74301081, -), ADediting_450975(74301086, -), ADediting_450976(74301149, -), ADediting_450977(74301245, -), ADediting_450978(74301284, -), ADediting_450979(74301306, -), ADediting_450980(74301319, -), ADediting_450981(74301324, -), ADediting_450982(74301342, -), ADediting_450983(74301379, -), ADediting_450984(74301439, -), ADediting_450985(74301685, -), ADediting_450986(74301690, -), ADediting_450987(74301695, -), ADediting_450988(74301702, -), ADediting_450989(74301733, -), ADediting_450990(74301737, -), ADediting_450991(74301753, -), ADediting_450992(74301757, -), ADediting_450993(74301761, -), ADediting_450994(74301777, -), ADediting_450995(74301779, -), ADediting_450996(74301789, -), ADediting_450997(74301818, -), ADediting_450998(74301819, -), ADediting_450999(74301855, -), ADediting_451000(74301861, -), ADediting_451001(74301869, -), ADediting_1537824(74287459, -), ADediting_1537825(74287478, -), ADediting_1537826(74288949, -), ADediting_1537827(74289050, -), ADediting_1537828(74290790, -), ADediting_1537829(74298478, -), ADediting_1537830(74298521, -), ADediting_1537831(74298543, -), ADediting_1537832(74299853, -), ADediting_1537833(74299894, -), ADediting_1537834(74299925, -), ADediting_1537835(74300017, -), ADediting_1537836(74300470, -), ADediting_1537837(74300920, -), ADediting_1537838(74300958, -), ADediting_1537839(74301021, -), ADediting_1537840(74301028, -), ADediting_1537841(74301285, -), ADediting_1537842(74301378, -), ADediting_1537843(74301406, -), ADediting_1537844(74301801, -), ADediting_1537845(74301836, -), |
Top |
RNA editing positional annotations for ABCD4 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_450900 | chr14_74288946_- | intronic |
| ADediting_450901 | chr14_74289000_- | intronic |
| ADediting_450902 | chr14_74289026_- | intronic |
| ADediting_450903 | chr14_74289030_- | intronic |
| ADediting_450904 | chr14_74289043_- | intronic |
| ADediting_450905 | chr14_74289049_- | intronic |
| ADediting_450906 | chr14_74290748_- | ncRNA_intronic |
| ADediting_450907 | chr14_74290752_- | ncRNA_intronic |
| ADediting_450908 | chr14_74290777_- | ncRNA_intronic |
| ADediting_450909 | chr14_74290781_- | ncRNA_intronic |
| ADediting_450910 | chr14_74290782_- | ncRNA_intronic |
| ADediting_450911 | chr14_74290792_- | ncRNA_intronic |
| ADediting_450912 | chr14_74290793_- | ncRNA_intronic |
| ADediting_450913 | chr14_74290821_- | ncRNA_intronic |
| ADediting_450914 | chr14_74290822_- | ncRNA_intronic |
| ADediting_450915 | chr14_74290866_- | ncRNA_intronic |
| ADediting_450916 | chr14_74290872_- | ncRNA_intronic |
| ADediting_450917 | chr14_74290876_- | ncRNA_intronic |
| ADediting_450918 | chr14_74290948_- | ncRNA_intronic |
| ADediting_450919 | chr14_74294058_- | ncRNA_exonic |
| ADediting_450920 | chr14_74294126_- | ncRNA_exonic |
| ADediting_450921 | chr14_74295766_- | intronic |
| ADediting_450922 | chr14_74296789_- | intronic |
| ADediting_450923 | chr14_74296901_- | intronic |
| ADediting_450924 | chr14_74297596_- | intronic |
| ADediting_450925 | chr14_74297611_- | intronic |
| ADediting_450926 | chr14_74297646_- | UTR3 |
| ADediting_450927 | chr14_74297684_- | UTR3 |
| ADediting_450928 | chr14_74297691_- | UTR3 |
| ADediting_450929 | chr14_74297692_- | UTR3 |
| ADediting_450930 | chr14_74297698_- | UTR3 |
| ADediting_450931 | chr14_74297873_- | UTR3 |
| ADediting_450932 | chr14_74298293_- | intronic |
| ADediting_450933 | chr14_74298339_- | intronic |
| ADediting_450934 | chr14_74298340_- | intronic |
| ADediting_450935 | chr14_74298377_- | intronic |
| ADediting_450936 | chr14_74298400_- | intronic |
| ADediting_450937 | chr14_74298444_- | intronic |
| ADediting_450938 | chr14_74298453_- | intronic |
| ADediting_450939 | chr14_74298474_- | intronic |
| ADediting_450940 | chr14_74298529_- | intronic |
| ADediting_450941 | chr14_74299817_- | intronic |
| ADediting_450942 | chr14_74299827_- | intronic |
| ADediting_450943 | chr14_74299845_- | intronic |
| ADediting_450944 | chr14_74299870_- | intronic |
| ADediting_450945 | chr14_74299890_- | intronic |
| ADediting_450946 | chr14_74299895_- | intronic |
| ADediting_450947 | chr14_74299896_- | intronic |
| ADediting_450948 | chr14_74299938_- | intronic |
| ADediting_450949 | chr14_74299941_- | intronic |
| ADediting_450950 | chr14_74299951_- | intronic |
| ADediting_450951 | chr14_74299980_- | intronic |
| ADediting_450952 | chr14_74299981_- | intronic |
| ADediting_450953 | chr14_74300001_- | intronic |
| ADediting_450954 | chr14_74300011_- | intronic |
| ADediting_450955 | chr14_74300016_- | intronic |
| ADediting_450956 | chr14_74300021_- | intronic |
| ADediting_450957 | chr14_74300480_- | intronic |
| ADediting_450958 | chr14_74300505_- | intronic |
| ADediting_450959 | chr14_74300516_- | intronic |
| ADediting_450960 | chr14_74300529_- | intronic |
| ADediting_450961 | chr14_74300545_- | intronic |
| ADediting_450962 | chr14_74300546_- | intronic |
| ADediting_450963 | chr14_74300553_- | intronic |
| ADediting_450964 | chr14_74300955_- | intronic |
| ADediting_450965 | chr14_74300977_- | intronic |
| ADediting_450966 | chr14_74300990_- | intronic |
| ADediting_450967 | chr14_74300991_- | intronic |
| ADediting_450968 | chr14_74301017_- | intronic |
| ADediting_450969 | chr14_74301026_- | intronic |
| ADediting_450970 | chr14_74301030_- | intronic |
| ADediting_450971 | chr14_74301031_- | intronic |
| ADediting_450972 | chr14_74301032_- | intronic |
| ADediting_450973 | chr14_74301035_- | intronic |
| ADediting_450974 | chr14_74301081_- | intronic |
| ADediting_450975 | chr14_74301086_- | intronic |
| ADediting_450976 | chr14_74301149_- | intronic |
| ADediting_450977 | chr14_74301245_- | intronic |
| ADediting_450978 | chr14_74301284_- | intronic |
| ADediting_450979 | chr14_74301306_- | intronic |
| ADediting_450980 | chr14_74301319_- | intronic |
| ADediting_450981 | chr14_74301324_- | intronic |
| ADediting_450982 | chr14_74301342_- | intronic |
| ADediting_450983 | chr14_74301379_- | intronic |
| ADediting_450984 | chr14_74301439_- | intronic |
| ADediting_450985 | chr14_74301685_- | intronic |
| ADediting_450986 | chr14_74301690_- | intronic |
| ADediting_450987 | chr14_74301695_- | intronic |
| ADediting_450988 | chr14_74301702_- | intronic |
| ADediting_450989 | chr14_74301733_- | intronic |
| ADediting_450990 | chr14_74301737_- | intronic |
| ADediting_450991 | chr14_74301753_- | intronic |
| ADediting_450992 | chr14_74301757_- | intronic |
| ADediting_450993 | chr14_74301761_- | intronic |
| ADediting_450994 | chr14_74301777_- | intronic |
| ADediting_450995 | chr14_74301779_- | intronic |
| ADediting_450996 | chr14_74301789_- | intronic |
| ADediting_450997 | chr14_74301818_- | intronic |
| ADediting_450998 | chr14_74301819_- | intronic |
| ADediting_450999 | chr14_74301855_- | intronic |
| ADediting_451000 | chr14_74301861_- | intronic |
| ADediting_451001 | chr14_74301869_- | intronic |
| ADediting_1537824 | chr14_74287459_- | intronic |
| ADediting_1537825 | chr14_74287478_- | intronic |
| ADediting_1537826 | chr14_74288949_- | intronic |
| ADediting_1537827 | chr14_74289050_- | intronic |
| ADediting_1537828 | chr14_74290790_- | ncRNA_intronic |
| ADediting_1537829 | chr14_74298478_- | intronic |
| ADediting_1537830 | chr14_74298521_- | intronic |
| ADediting_1537831 | chr14_74298543_- | intronic |
| ADediting_1537832 | chr14_74299853_- | intronic |
| ADediting_1537833 | chr14_74299894_- | intronic |
| ADediting_1537834 | chr14_74299925_- | intronic |
| ADediting_1537835 | chr14_74300017_- | intronic |
| ADediting_1537836 | chr14_74300470_- | intronic |
| ADediting_1537837 | chr14_74300920_- | intronic |
| ADediting_1537838 | chr14_74300958_- | intronic |
| ADediting_1537839 | chr14_74301021_- | intronic |
| ADediting_1537840 | chr14_74301028_- | intronic |
| ADediting_1537841 | chr14_74301285_- | intronic |
| ADediting_1537842 | chr14_74301378_- | intronic |
| ADediting_1537843 | chr14_74301406_- | intronic |
| ADediting_1537844 | chr14_74301801_- | intronic |
| ADediting_1537845 | chr14_74301836_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_450900 | chr14_74288946_- | SINE | Alu | Name=AluSg |
| ADediting_450901 | chr14_74289000_- | SINE | Alu | Name=AluSg |
| ADediting_450902 | chr14_74289026_- | SINE | Alu | Name=AluSg |
| ADediting_450903 | chr14_74289030_- | SINE | Alu | Name=AluSg |
| ADediting_450904 | chr14_74289043_- | SINE | Alu | Name=AluSg |
| ADediting_450905 | chr14_74289049_- | SINE | Alu | Name=AluSg |
| ADediting_450906 | chr14_74290748_- | SINE | Alu | Name=AluSx1 |
| ADediting_450907 | chr14_74290752_- | SINE | Alu | Name=AluSx1 |
| ADediting_450908 | chr14_74290777_- | SINE | Alu | Name=AluSx1 |
| ADediting_450909 | chr14_74290781_- | SINE | Alu | Name=AluSx1 |
| ADediting_450910 | chr14_74290782_- | SINE | Alu | Name=AluSx1 |
| ADediting_450911 | chr14_74290792_- | SINE | Alu | Name=AluSx1 |
| ADediting_450912 | chr14_74290793_- | SINE | Alu | Name=AluSx1 |
| ADediting_450913 | chr14_74290821_- | SINE | Alu | Name=AluSx1 |
| ADediting_450914 | chr14_74290822_- | SINE | Alu | Name=AluSx1 |
| ADediting_450915 | chr14_74290866_- | SINE | Alu | Name=AluSx1 |
| ADediting_450916 | chr14_74290872_- | SINE | Alu | Name=AluSx1 |
| ADediting_450917 | chr14_74290876_- | SINE | Alu | Name=AluSx1 |
| ADediting_450918 | chr14_74290948_- | SINE | Alu | Name=AluSx1 |
| ADediting_450919 | chr14_74294058_- | SINE | Alu | Name=AluSx1 |
| ADediting_450920 | chr14_74294126_- | SINE | Alu | Name=AluSx1 |
| ADediting_450921 | chr14_74295766_- | SINE | MIR | Name=MIR |
| ADediting_450923 | chr14_74296901_- | SINE | Alu | Name=AluSx3 |
| ADediting_450924 | chr14_74297596_- | SINE | Alu | Name=FAM |
| ADediting_450925 | chr14_74297611_- | SINE | Alu | Name=FAM |
| ADediting_450926 | chr14_74297646_- | SINE | Alu | Name=FAM |
| ADediting_450927 | chr14_74297684_- | SINE | Alu | Name=FAM |
| ADediting_450928 | chr14_74297691_- | SINE | Alu | Name=FAM |
| ADediting_450929 | chr14_74297692_- | SINE | Alu | Name=FAM |
| ADediting_450930 | chr14_74297698_- | SINE | Alu | Name=FAM |
| ADediting_450932 | chr14_74298293_- | SINE | Alu | Name=AluSp |
| ADediting_450933 | chr14_74298339_- | SINE | Alu | Name=AluSp |
| ADediting_450934 | chr14_74298340_- | SINE | Alu | Name=AluSp |
| ADediting_450935 | chr14_74298377_- | SINE | Alu | Name=AluSp |
| ADediting_450936 | chr14_74298400_- | SINE | Alu | Name=AluSp |
| ADediting_450937 | chr14_74298444_- | SINE | Alu | Name=AluSp |
| ADediting_450938 | chr14_74298453_- | SINE | Alu | Name=AluSp |
| ADediting_450939 | chr14_74298474_- | SINE | Alu | Name=AluSp |
| ADediting_450940 | chr14_74298529_- | SINE | Alu | Name=AluSp |
| ADediting_450941 | chr14_74299817_- | SINE | Alu | Name=AluSq |
| ADediting_450942 | chr14_74299827_- | SINE | Alu | Name=AluSq |
| ADediting_450943 | chr14_74299845_- | SINE | Alu | Name=AluSq |
| ADediting_450944 | chr14_74299870_- | SINE | Alu | Name=AluSq |
| ADediting_450945 | chr14_74299890_- | SINE | Alu | Name=AluSq |
| ADediting_450946 | chr14_74299895_- | SINE | Alu | Name=AluSq |
| ADediting_450947 | chr14_74299896_- | SINE | Alu | Name=AluSq |
| ADediting_450948 | chr14_74299938_- | SINE | Alu | Name=AluSq |
| ADediting_450949 | chr14_74299941_- | SINE | Alu | Name=AluSq |
| ADediting_450950 | chr14_74299951_- | SINE | Alu | Name=AluSq |
| ADediting_450951 | chr14_74299980_- | SINE | Alu | Name=AluSq |
| ADediting_450952 | chr14_74299981_- | SINE | Alu | Name=AluSq |
| ADediting_450953 | chr14_74300001_- | SINE | Alu | Name=AluSq |
| ADediting_450954 | chr14_74300011_- | SINE | Alu | Name=AluSq |
| ADediting_450955 | chr14_74300016_- | SINE | Alu | Name=AluSq |
| ADediting_450956 | chr14_74300021_- | SINE | Alu | Name=AluSq |
| ADediting_450957 | chr14_74300480_- | SINE | Alu | Name=AluSp |
| ADediting_450958 | chr14_74300505_- | SINE | Alu | Name=AluSp |
| ADediting_450959 | chr14_74300516_- | SINE | Alu | Name=AluSp |
| ADediting_450960 | chr14_74300529_- | SINE | Alu | Name=AluSp |
| ADediting_450961 | chr14_74300545_- | SINE | Alu | Name=AluSp |
| ADediting_450962 | chr14_74300546_- | SINE | Alu | Name=AluSp |
| ADediting_450963 | chr14_74300553_- | SINE | Alu | Name=AluSp |
| ADediting_450964 | chr14_74300955_- | SINE | Alu | Name=AluSq2 |
| ADediting_450965 | chr14_74300977_- | SINE | Alu | Name=AluSq2 |
| ADediting_450966 | chr14_74300990_- | SINE | Alu | Name=AluSq2 |
| ADediting_450967 | chr14_74300991_- | SINE | Alu | Name=AluSq2 |
| ADediting_450968 | chr14_74301017_- | SINE | Alu | Name=AluSq2 |
| ADediting_450969 | chr14_74301026_- | SINE | Alu | Name=AluSq2 |
| ADediting_450970 | chr14_74301030_- | SINE | Alu | Name=AluSq2 |
| ADediting_450971 | chr14_74301031_- | SINE | Alu | Name=AluSq2 |
| ADediting_450972 | chr14_74301032_- | SINE | Alu | Name=AluSq2 |
| ADediting_450973 | chr14_74301035_- | SINE | Alu | Name=AluSq2 |
| ADediting_450974 | chr14_74301081_- | SINE | Alu | Name=AluSq2 |
| ADediting_450975 | chr14_74301086_- | SINE | Alu | Name=AluSq2 |
| ADediting_450976 | chr14_74301149_- | SINE | Alu | Name=AluSq2 |
| ADediting_450977 | chr14_74301245_- | SINE | Alu | Name=AluSz |
| ADediting_450978 | chr14_74301284_- | SINE | Alu | Name=AluSz |
| ADediting_450979 | chr14_74301306_- | SINE | Alu | Name=AluSz |
| ADediting_450980 | chr14_74301319_- | SINE | Alu | Name=AluSz |
| ADediting_450981 | chr14_74301324_- | SINE | Alu | Name=AluSz |
| ADediting_450982 | chr14_74301342_- | SINE | Alu | Name=AluSz |
| ADediting_450983 | chr14_74301379_- | SINE | Alu | Name=AluSz |
| ADediting_450984 | chr14_74301439_- | SINE | Alu | Name=AluSz |
| ADediting_450985 | chr14_74301685_- | SINE | Alu | Name=AluSq |
| ADediting_450986 | chr14_74301690_- | SINE | Alu | Name=AluSq |
| ADediting_450987 | chr14_74301695_- | SINE | Alu | Name=AluSq |
| ADediting_450988 | chr14_74301702_- | SINE | Alu | Name=AluSq |
| ADediting_450989 | chr14_74301733_- | SINE | Alu | Name=AluSq |
| ADediting_450990 | chr14_74301737_- | SINE | Alu | Name=AluSq |
| ADediting_450991 | chr14_74301753_- | SINE | Alu | Name=AluSq |
| ADediting_450992 | chr14_74301757_- | SINE | Alu | Name=AluSq |
| ADediting_450993 | chr14_74301761_- | SINE | Alu | Name=AluSq |
| ADediting_450994 | chr14_74301777_- | SINE | Alu | Name=AluSq |
| ADediting_450995 | chr14_74301779_- | SINE | Alu | Name=AluSq |
| ADediting_450996 | chr14_74301789_- | SINE | Alu | Name=AluSq |
| ADediting_450997 | chr14_74301818_- | SINE | Alu | Name=AluSq |
| ADediting_450998 | chr14_74301819_- | SINE | Alu | Name=AluSq |
| ADediting_450999 | chr14_74301855_- | SINE | Alu | Name=AluSq |
| ADediting_451000 | chr14_74301861_- | SINE | Alu | Name=AluSq |
| ADediting_451001 | chr14_74301869_- | SINE | Alu | Name=AluSq |
| ADediting_1537824 | chr14_74287459_- | SINE | Alu | Name=AluJr |
| ADediting_1537825 | chr14_74287478_- | SINE | Alu | Name=AluJr |
| ADediting_1537826 | chr14_74288949_- | SINE | Alu | Name=AluSg |
| ADediting_1537827 | chr14_74289050_- | SINE | Alu | Name=AluSg |
| ADediting_1537828 | chr14_74290790_- | SINE | Alu | Name=AluSx1 |
| ADediting_1537829 | chr14_74298478_- | SINE | Alu | Name=AluSp |
| ADediting_1537830 | chr14_74298521_- | SINE | Alu | Name=AluSp |
| ADediting_1537831 | chr14_74298543_- | SINE | Alu | Name=AluSp |
| ADediting_1537832 | chr14_74299853_- | SINE | Alu | Name=AluSq |
| ADediting_1537833 | chr14_74299894_- | SINE | Alu | Name=AluSq |
| ADediting_1537834 | chr14_74299925_- | SINE | Alu | Name=AluSq |
| ADediting_1537835 | chr14_74300017_- | SINE | Alu | Name=AluSq |
| ADediting_1537836 | chr14_74300470_- | SINE | Alu | Name=AluSp |
| ADediting_1537837 | chr14_74300920_- | SINE | Alu | Name=AluSq2 |
| ADediting_1537838 | chr14_74300958_- | SINE | Alu | Name=AluSq2 |
| ADediting_1537839 | chr14_74301021_- | SINE | Alu | Name=AluSq2 |
| ADediting_1537840 | chr14_74301028_- | SINE | Alu | Name=AluSq2 |
| ADediting_1537841 | chr14_74301285_- | SINE | Alu | Name=AluSz |
| ADediting_1537842 | chr14_74301378_- | SINE | Alu | Name=AluSz |
| ADediting_1537843 | chr14_74301406_- | SINE | Alu | Name=AluSz |
| ADediting_1537844 | chr14_74301801_- | SINE | Alu | Name=AluSq |
| ADediting_1537845 | chr14_74301836_- | SINE | Alu | Name=AluSq |
Top |
RNA A-to-I editing events in the alternative splicing sites for ABCD4 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| ES | ADediting_450943 | chr14_74299845_- | 74299838:74299846 | 5ss | 2e | CAGGTGATA | 4.58 | CGGGTGATA | 1.33 |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for ABCD4 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for ABCD4 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for ABCD4 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1537834 | chr14_74299925_- | ENSG00000119688.21 | ENST00000489207.1 | ABCD4-213 | hsa-miR-10394-3p | chr14 | 74299920 | 74299926 | 7mer-m8 | 74299919 | 74299942 | 145 | -25.02 |
| ADediting_1537834 | chr14_74299925_- | ENSG00000119688.21 | ENST00000489207.1 | ABCD4-213 | hsa-miR-3178 | chr14 | 74299920 | 74299926 | 7mer-m8 | 74299919 | 74299935 | 145 | -22.6 |
| ADediting_1537835 | chr14_74300017_- | ENSG00000119688.21 | ENST00000489207.1 | ABCD4-213 | hsa-miR-5694 | chr14 | 74300013 | 74300019 | 7mer-m8 | 74300012 | 74300033 | 166 | -23.19 |
| ADediting_1537835 | chr14_74300017_- | ENSG00000119688.21 | ENST00000489207.1 | ABCD4-213 | hsa-miR-96-3p | chr14 | 74300015 | 74300021 | 7mer-m8 | 74300014 | 74300034 | 153 | -14.54 |
| ADediting_450948 | chr14_74299938_- | ENSG00000119688.21 | ENST00000489207.1 | ABCD4-213 | hsa-miR-1271-3p | chr14 | 74299934 | 74299940 | 7mer-m8 | 74299933 | 74299952 | 155 | -21.49 |
| ADediting_450948 | chr14_74299938_- | ENSG00000119688.21 | ENST00000489207.1 | ABCD4-213 | hsa-miR-550a-3-5p | chr14 | 74299934 | 74299940 | 7mer-m8 | 74299933 | 74299952 | 140 | -14.45 |
| ADediting_450948 | chr14_74299938_- | ENSG00000119688.21 | ENST00000489207.1 | ABCD4-213 | hsa-miR-550a-5p | chr14 | 74299934 | 74299940 | 7mer-m8 | 74299933 | 74299955 | 140 | -18.24 |
| ADediting_450948 | chr14_74299938_- | ENSG00000119688.21 | ENST00000489207.1 | ABCD4-213 | hsa-miR-6514-3p | chr14 | 74299935 | 74299941 | 7mer-m8 | 74299934 | 74299955 | 158 | -19.3 |
| ADediting_450949 | chr14_74299941_- | ENSG00000119688.21 | ENST00000489207.1 | ABCD4-213 | hsa-miR-4327 | chr14 | 74299935 | 74299942 | 8mer-1a | 74299935 | 74299953 | 140 | -13.38 |
| ADediting_450950 | chr14_74299951_- | ENSG00000119688.21 | ENST00000489207.1 | ABCD4-213 | hsa-miR-4691-3p | chr14 | 74299947 | 74299953 | 7mer-m8 | 74299946 | 74299970 | 146 | -24.35 |
| ADediting_450951 | chr14_74299980_- | ENSG00000119688.21 | ENST00000489207.1 | ABCD4-213 | hsa-miR-3622a-3p | chr14 | 74299976 | 74299983 | 8mer-1a | 74299976 | 74299997 | 143 | -16.73 |
| ADediting_450951 | chr14_74299980_- | ENSG00000119688.21 | ENST00000489207.1 | ABCD4-213 | hsa-miR-3622b-3p | chr14 | 74299976 | 74299983 | 8mer-1a | 74299976 | 74299996 | 147 | -17.72 |
| ADediting_450954 | chr14_74300011_- | ENSG00000119688.21 | ENST00000489207.1 | ABCD4-213 | hsa-miR-4537 | chr14 | 74300006 | 74300013 | 8mer-1a | 74300006 | 74300027 | 154 | -22.63 |
| ADediting_450955 | chr14_74300016_- | ENSG00000119688.21 | ENST00000489207.1 | ABCD4-213 | hsa-miR-10525-3p | chr14 | 74300014 | 74300020 | 7mer-m8 | 74300013 | 74300034 | 155 | -16.23 |
| ADediting_450955 | chr14_74300016_- | ENSG00000119688.21 | ENST00000489207.1 | ABCD4-213 | hsa-miR-3672 | chr14 | 74300011 | 74300017 | 7mer-m8 | 74300010 | 74300031 | 153 | -15.12 |
| ADediting_450955 | chr14_74300016_- | ENSG00000119688.21 | ENST00000489207.1 | ABCD4-213 | hsa-miR-6864-3p | chr14 | 74300011 | 74300017 | 7mer-m8 | 74300010 | 74300033 | 150 | -16.78 |
| ADediting_450956 | chr14_74300021_- | ENSG00000119688.21 | ENST00000489207.1 | ABCD4-213 | hsa-miR-324-3p | chr14 | 74300021 | 74300027 | 7mer-m8 | 74300020 | 74300158 | 147 | -23.68 |
| ADediting_450956 | chr14_74300021_- | ENSG00000119688.21 | ENST00000489207.1 | ABCD4-213 | hsa-miR-4252 | chr14 | 74300019 | 74300026 | 8mer-1a | 74300019 | 74300153 | 151 | -26.21 |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_450950 | chr14_74299951_- | ENSG00000119688.21 | ENST00000489207.1 | ABCD4-213 | hsa-miR-5690 | chr14 | 74299947 | 74299953 | 7mer-m8 | 74299946 | 74299966 | 145 | -16.91 |
| ADediting_450951 | chr14_74299980_- | ENSG00000119688.21 | ENST00000489207.1 | ABCD4-213 | hsa-miR-3614-5p | chr14 | 74299976 | 74299982 | 7mer-1a | 74299976 | 74299999 | 147 | -21.49 |
| ADediting_450952 | chr14_74299981_- | ENSG00000119688.21 | ENST00000489207.1 | ABCD4-213 | hsa-miR-3614-5p | chr14 | 74299976 | 74299982 | 7mer-1a | 74299976 | 74299999 | 147 | -21.49 |
| ADediting_450953 | chr14_74300001_- | ENSG00000119688.21 | ENST00000489207.1 | ABCD4-213 | hsa-miR-377-5p | chr14 | 74299996 | 74300002 | 7mer-m8 | 74299995 | 74300018 | 154 | -19.16 |
| ADediting_450953 | chr14_74300001_- | ENSG00000119688.21 | ENST00000489207.1 | ABCD4-213 | hsa-miR-6086 | chr14 | 74299996 | 74300002 | 7mer-m8 | 74299995 | 74300014 | 150 | -20.67 |
| ADediting_450953 | chr14_74300001_- | ENSG00000119688.21 | ENST00000489207.1 | ABCD4-213 | hsa-miR-6516-5p | chr14 | 74300000 | 74300006 | 7mer-m8 | 74299999 | 74300018 | 148 | -12.72 |
| ADediting_450956 | chr14_74300021_- | ENSG00000119688.21 | ENST00000489207.1 | ABCD4-213 | hsa-miR-668-3p | chr14 | 74300019 | 74300025 | 7mer-1a | 74300019 | 74300156 | 140 | -27.89 |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_496066 | chr15_66496985_- | ENSG00000119688.21 | ENST00000556517.1 | ABCD4-225 | hsa-miR-4512 | chr14 | 74286626 | 74286632 | 7mer-m8 | 74286625 | 74286646 | 148 | -23.28 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000119688.21 | ENST00000356924.9 | ABCD4-201 | hsa-miR-4775 | chr14 | 74285286 | 74285292 | 7mer-m8 | 74285285 | 74285306 | 142 | -8.71 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337757 | chr7_5495852_- | ENSG00000119688.21 | ENST00000356924.9 | ABCD4-201 | hsa-miR-589-3p | chr14 | 74285890 | 74285896 | 7mer-m8 | 74285889 | 74285915 | 146 | -19.01 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000119688.21 | ENST00000356924.9 | ABCD4-201 | hsa-miR-4477b | chr14 | 74285294 | 74285300 | 7mer-m8 | 74285293 | 74285314 | 142 | -7.64 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000119688.21 | ENST00000356924.9 | ABCD4-201 | hsa-miR-4477b | chr14 | 74285294 | 74285300 | 7mer-m8 | 74285293 | 74285314 | 142 | -7.64 |
| Differentially expressed gene-miRNA network |
Top |
The effects of the RNA editing to the stability of the RNA structures for ABCD4 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000489207.1 | lncRNA |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_1537834 | ENST00000489207.1 | chr14_74299925_- | 353 | -130.90 | -131.60 | -147.90 |
| ADediting_450948 | ENST00000489207.1 | chr14_74299938_- | 340 | -131.60 | -131.60 | -147.90 |
| ADediting_450949 | ENST00000489207.1 | chr14_74299941_- | 337 | -131.30 | -131.60 | -147.90 |
| ADediting_450950 | ENST00000489207.1 | chr14_74299951_- | 327 | -134.20 | -131.60 | -147.90 |
| ADediting_450951 | ENST00000489207.1 | chr14_74299980_- | 298 | -134.20 | -131.60 | -147.90 |
| ADediting_450952 | ENST00000489207.1 | chr14_74299981_- | 297 | -132.70 | -131.60 | -147.90 |
| ADediting_450953 | ENST00000489207.1 | chr14_74300001_- | 277 | -132.00 | -131.60 | -147.90 |
| ADediting_450954 | ENST00000489207.1 | chr14_74300011_- | 267 | -130.90 | -131.60 | -147.90 |
| ADediting_450955 | ENST00000489207.1 | chr14_74300016_- | 262 | -131.60 | -131.60 | -147.90 |
| ADediting_1537835 | ENST00000489207.1 | chr14_74300017_- | 261 | -132.40 | -131.60 | -147.90 |
| ADediting_450956 | ENST00000489207.1 | chr14_74300021_- | 257 | -131.90 | -131.60 | -147.90 |
Top |
Relation with ADAR for ABCD4 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_1537826 | chr14_74288949_- | 0.0966651059717978 | 0.136146333055117 | 5.2529152747015e-05 | 0.323958053283938 | 0.394871663788675 | 0.0699689536277497 |
| CER | ADediting_1537828 | chr14_74290790_- | 0.0180983067418024 | 0.192785922609815 | 6.0141199301534e-05 | 0.32154600943945 | 0.235082503863896 | 0.0975327681477821 |
| CER | ADediting_1537832 | chr14_74299853_- | 1.7172664210603e-05 | 0.343148367529791 | 5.87513253662389e-09 | 0.452976042652931 | 0.09350541609322 | 0.137441042188878 |
| CER | ADediting_450900 | chr14_74288946_- | 0.0119160620681143 | 0.204849405055901 | 1.53499032845479e-07 | 0.412716692512158 | 0.00498645557724015 | 0.228141670847525 |
| CER | ADediting_450901 | chr14_74289000_- | 0.01056942188277 | 0.20819627214632 | 7.63541237003969e-08 | 0.421784561716151 | 0.00593704919339283 | 0.223655705771104 |
| CER | ADediting_450902 | chr14_74289026_- | 0.0436775843069845 | 0.164951293202027 | 3.83241348193839e-07 | 0.400415352048769 | 0.0162220877206526 | 0.19600786937431 |
| CER | ADediting_450904 | chr14_74289043_- | 0.0130602177532727 | 0.20225735805851 | 1.61430507104525e-08 | 0.441055133852544 | 0.00107302851409065 | 0.26448759738025 |
| CER | ADediting_450905 | chr14_74289049_- | 0.0229897041985907 | 0.185576015191599 | 1.50458265954607e-08 | 0.441900301212483 | 0.0101440775196033 | 0.209331572848051 |
| CER | ADediting_450906 | chr14_74290748_- | 0.0153080279740997 | 0.19769664758348 | 2.06763684077005e-07 | 0.408765730199318 | 0.0036577213377492 | 0.235910275122292 |
| CER | ADediting_450908 | chr14_74290777_- | 0.0535578271985451 | 0.157946624739293 | 4.2982903428691e-08 | 0.429050822853741 | 0.00428665002657744 | 0.231963457439063 |
| CER | ADediting_450909 | chr14_74290781_- | 0.0405912131507671 | 0.167411132361198 | 4.44075125980265e-06 | 0.364795541830301 | 0.00231196871404564 | 0.2469805093839 |
| CER | ADediting_450911 | chr14_74290792_- | 0.0221292722418686 | 0.186741591570223 | 3.68850085187866e-08 | 0.430957199243214 | 0.00105598124344966 | 0.264840506701395 |
| CER | ADediting_450912 | chr14_74290793_- | 0.0496029253661202 | 0.160609974400422 | 6.79260536666702e-06 | 0.358162277439373 | 0.00820569977080992 | 0.215106501222461 |
| CER | ADediting_450915 | chr14_74290866_- | 0.010124398191517 | 0.209385108111713 | 4.75263208099502e-07 | 0.397448782202239 | 0.00184122729707156 | 0.25229879048478 |
| CER | ADediting_450916 | chr14_74290872_- | 0.0107417991169457 | 0.207747600898914 | 3.23654786779314e-09 | 0.459799107377672 | 0.000329744462953092 | 0.289307468234535 |
| CER | ADediting_450918 | chr14_74290948_- | 0.00952121309790136 | 0.211072229235234 | 1.71779872650448e-09 | 0.466887877189398 | 0.000243586256325709 | 0.295325847892217 |
| CER | ADediting_450923 | chr14_74296901_- | 7.01147604133592e-07 | 0.39201422259874 | 7.18496725876817e-05 | 0.318344105435523 | 0.268227901832343 | 0.0909720762054677 |
| CER | ADediting_450928 | chr14_74297691_- | 1.40645425502204e-06 | 0.382035818586983 | 2.75001052285679e-06 | 0.37210204389083 | 0.0322409294622176 | 0.174958139358565 |
| CER | ADediting_450930 | chr14_74297698_- | 2.48113598864547e-08 | 0.435843742313142 | 1.19944498551555e-05 | 0.349048968969016 | 0.246151747349957 | 0.0952743998053567 |
| CER | ADediting_450934 | chr14_74298340_- | 2.88553306008755e-06 | 0.371376603826816 | 4.75119112421669e-06 | 0.363750767098021 | 0.0267495649776884 | 0.180885003627685 |
| CER | ADediting_450935 | chr14_74298377_- | 6.54886314454626e-05 | 0.320017217321328 | 1.10900477331061e-05 | 0.350322311769268 | 0.185528447575347 | 0.108686598147788 |
| CER | ADediting_450940 | chr14_74298529_- | 0.00557119236782489 | 0.225300581326553 | 0.000107152112902747 | 0.31101511044552 | 0.900506114602946 | -0.0102938481034396 |
| TCX | ADediting_450940 | chr14_74298529_- | 0.00144492090881717 | 0.257841533623435 | 2.57815300906806e-05 | 0.336320202843405 | 0.96206698664103 | 0.00391599437358675 |
| DLPFC | ADediting_450942 | chr14_74299827_- | 0.000973962023474022 | 0.186419005018172 | 0.527132331987656 | 0.0360512759829868 | 1.78946146463228e-13 | 0.40206982898596 |
| CER | ADediting_450944 | chr14_74299870_- | 0.00557772987029369 | 0.225270353383433 | 9.79147287723827e-05 | 0.312684977011708 | 0.107210431718544 | 0.132054128199588 |
| CER | ADediting_450945 | chr14_74299890_- | 0.00105548557602815 | 0.264850845758633 | 8.1828738383872e-06 | 0.355208695324938 | 0.352863528446287 | 0.0763846549569464 |
| CER | ADediting_450946 | chr14_74299895_- | 0.000940961492683198 | 0.267367900209143 | 7.82941722336604e-06 | 0.355911742878943 | 0.0357715706026618 | 0.171586552375796 |
| DLPFC | ADediting_450948 | chr14_74299938_- | 0.000170593933369941 | 0.211923019751087 | 0.0189447221007584 | 0.133222453713628 | 4.81132810100608e-09 | 0.324719959140465 |
| CER | ADediting_450948 | chr14_74299938_- | 7.06002350355548e-05 | 0.318661484260202 | 2.55160484046882e-08 | 0.435501113883292 | 0.0413053036114252 | 0.16682841150259 |
| CER | ADediting_450949 | chr14_74299941_- | 2.41748180301233e-05 | 0.33741223228261 | 8.82276617872066e-09 | 0.448235423799482 | 0.0164100852664001 | 0.195670837954994 |
| CER | ADediting_450950 | chr14_74299951_- | 3.37708490939136e-05 | 0.331693657404817 | 3.1892430005077e-08 | 0.432758541182625 | 0.00235861541189018 | 0.24650851678079 |
| CER | ADediting_450951 | chr14_74299980_- | 0.000340169323321057 | 0.288681339668638 | 2.28769814624049e-05 | 0.338345436161172 | 0.000294538934478318 | 0.291566737106551 |
| CER | ADediting_450952 | chr14_74299981_- | 0.00724230013895189 | 0.218442338142677 | 4.99649710361341e-05 | 0.324844934513587 | 0.0105479623026008 | 0.208252578178904 |
| DLPFC | ADediting_450954 | chr14_74300011_- | 8.77721335704805e-05 | 0.220896107127395 | 0.0143349410901308 | 0.138966074694037 | 8.25866419783488e-09 | 0.319969202897642 |
| CER | ADediting_450954 | chr14_74300011_- | 1.07085618520113e-05 | 0.350889096313207 | 1.41597142181279e-09 | 0.469018394604405 | 0.00442250689911125 | 0.231179796651789 |
| DLPFC | ADediting_450986 | chr14_74301690_- | 0.170331243188181 | 0.0780720135385018 | 0.368521442646648 | -0.0512472204709976 | 3.29425979707196e-12 | 0.382001772323485 |
| DLPFC | ADediting_450993 | chr14_74301761_- | 0.484436827086395 | 0.0398562305111285 | 0.139944643204631 | -0.0840221354812746 | 5.88835222364615e-17 | 0.451244342397452 |
| DLPFC | ADediting_450994 | chr14_74301777_- | 0.752276963372606 | 0.0179983148359992 | 0.109672480207357 | -0.0910339938572455 | 2.76135051749263e-12 | 0.38325709331845 |
| DLPFC | ADediting_450995 | chr14_74301779_- | 0.307510041942498 | 0.0581441115941617 | 0.663021442235863 | -0.0248452250630858 | 4.26430761047097e-11 | 0.363150714263649 |
| DLPFC | ADediting_450996 | chr14_74301789_- | 0.489862476444204 | 0.0393631452852203 | 0.383163549881789 | -0.0497011015905765 | 3.10061725892544e-11 | 0.36556449732344 |
| DLPFC | ADediting_450997 | chr14_74301818_- | 0.0158566698144725 | 0.136910984437681 | 0.326084506824999 | 0.0559579634296377 | 2.71373979333659e-08 | 0.309206664051455 |
| DLPFC | ADediting_450999 | chr14_74301855_- | 0.00838828570549748 | 0.149478126196462 | 0.419022757535895 | 0.0460597136757535 | 8.89654819631969e-10 | 0.339055878523277 |
| DLPFC | ADediting_451000 | chr14_74301861_- | 0.01226204448808 | 0.142098237129685 | 0.520459192381185 | 0.0366351129122549 | 1.06383022840221e-13 | 0.405514190490816 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 3.91506713906138e-17 | 0.453545843538124 | 1.54130656338455e-14 | 0.417972978716559 | 2.25320506233312e-39 | 0.655035412810083 |
| AC | 3.65458971419287e-42 | 0.725717078221503 | 6.40778627742671e-27 | 0.610453197897517 | 9.21476254823117e-25 | 0.589226920726559 |
| PCC | 1.43364127311356e-08 | 0.395928956555125 | 2.25822047551193e-06 | 0.334455822478491 | 1.97820321197001e-08 | 0.392374525039527 |
| CER | 7.30535902208837e-14 | 0.561964797300385 | 1.75773477292014e-33 | 0.79166706377533 | 2.88439034605828e-07 | 0.404289167287254 |
| TCX | 4.67295499479169e-05 | 0.326027012844545 | 0.718786456343018 | 0.0296420086757645 | 2.48110455129385e-22 | 0.687688602058164 |
| FP | 1.82467666299296e-13 | 0.51537930886088 | 1.30933037929885e-06 | 0.353369052021589 | 2.09693300106108e-15 | 0.549065524642593 |
| IFG | 0.000464694588222416 | 0.64768826727902 | 0.000361267452056366 | 0.656872314443162 | 0.000172472402144301 | 0.682192520434697 |
| PG | 2.35769631489201e-07 | 0.36807641114656 | 7.76503241592149e-08 | 0.381501723252749 | 1.63407291558162e-06 | 0.343103784105893 |
| STG | 0.000199738043542392 | 0.395092337085337 | 0.0512297828255389 | 0.213453299464083 | 2.31181916210823e-07 | 0.528941673964666 |
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Relation with AD stages for ABCD4 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_450904 | chr14_74289043_- | 0.00159142761729965 | 0.300278416939275 |
| CER | ADediting_450908 | chr14_74290777_- | 0.00122697536865287 | 0.307072921068445 |
| CER | ADediting_450911 | chr14_74290792_- | 0.000162178518903232 | 0.355153116244852 |
| CER | ADediting_450916 | chr14_74290872_- | 8.8806554377146e-05 | 0.368088075974044 |
| CER | ADediting_450918 | chr14_74290948_- | 1.82227326607501e-06 | 0.440613144194982 |
| CER | ADediting_450950 | chr14_74299951_- | 0.000946299327346543 | 0.313702460386559 |
| CER | ADediting_450954 | chr14_74300011_- | 3.34348292587883e-05 | 0.387971329390635 |
| TCX | ADediting_450930 | chr14_74297698_- | 2.56235477396802e-07 | 0.47567959278555 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 1.25299933163483e-09 | 0.543146934668923 |
| TCX | 1.9929121278202e-06 | 0.442898381696534 |
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RelatedDrugs for ABCD4 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ABCD4 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| ABCD4 | C0009402 | Colorectal Carcinoma | 1 | CTD_human |
| ABCD4 | C0009404 | Colorectal Neoplasms | 1 | CTD_human |
| ABCD4 | C0025521 | Inborn Errors of Metabolism | 1 | CTD_human |
| ABCD4 | C0042847 | Vitamin B 12 Deficiency | 1 | CTD_human |
| ABCD4 | C0235874 | Disease Exacerbation | 1 | CTD_human |
| ABCD4 | C1527249 | Colorectal Cancer | 1 | CTD_human |
| ABCD4 | C3553915 | METHYLMALONIC ACIDURIA AND HOMOCYSTINURIA, cblJ TYPE | 1 | CTD_human;ORPHANET;UNIPROT |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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