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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for FBRSL1 |
 Gene summary |
| Gene information | Gene symbol | FBRSL1 | Gene ID | 57666 |
| Gene name | fibrosin like 1 | |
| Synonyms | - | |
| Cytomap | 12q24.33 | |
| Type of gene | protein-coding | |
| Description | fibrosin-1-like proteinAUTS2-like proteinHBV X-transactivated gene 9 proteinHBV XAg-transactivated protein 9 | |
| Modification date | 20200313 | |
| UniProtAcc | Q9HCM7, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for FBRSL1 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_330348(132515622, +), ADediting_330349(132515666, +), ADediting_330350(132515667, +), ADediting_330351(132515670, +), ADediting_330352(132515685, +), ADediting_330353(132515690, +), ADediting_330354(132515698, +), ADediting_330355(132515699, +), ADediting_330356(132515704, +), ADediting_330357(132515714, +), ADediting_330358(132515724, +), ADediting_330359(132515737, +), ADediting_330360(132515738, +), ADediting_330361(132515753, +), ADediting_330362(132515757, +), ADediting_330363(132515779, +), ADediting_330364(132515802, +), ADediting_330365(132515811, +), ADediting_330366(132515815, +), ADediting_330367(132516227, +), ADediting_330368(132516230, +), ADediting_330369(132516288, +), ADediting_330370(132516302, +), ADediting_330371(132516324, +), ADediting_330372(132516326, +), ADediting_330373(132516331, +), ADediting_330374(132516340, +), ADediting_330375(132516350, +), ADediting_330376(132516351, +), ADediting_330377(132516359, +), ADediting_330378(132516365, +), ADediting_330379(132516368, +), ADediting_330380(132516382, +), ADediting_330381(132516407, +), ADediting_330382(132516447, +), ADediting_330383(132551285, +), ADediting_330384(132554707, +), ADediting_330385(132554733, +), ADediting_330386(132554746, +), ADediting_330387(132554797, +), ADediting_330388(132554800, +), ADediting_330389(132554824, +), ADediting_330390(132554826, +), ADediting_330391(132554827, +), ADediting_330392(132554867, +), ADediting_330393(132554868, +), ADediting_330394(132554888, +), ADediting_330395(132554912, +), ADediting_330396(132554930, +), ADediting_330397(132559431, +), ADediting_330398(132559455, +), ADediting_330399(132559456, +), ADediting_330400(132559466, +), ADediting_330401(132559491, +), ADediting_330402(132559521, +), ADediting_330403(132559533, +), ADediting_330404(132559547, +), ADediting_330405(132559557, +), ADediting_330406(132559558, +), ADediting_330407(132559602, +), ADediting_330408(132559636, +), ADediting_330409(132559637, +), ADediting_330410(132559649, +), ADediting_330411(132559663, +), ADediting_330412(132566811, +), ADediting_330413(132571792, +), ADediting_330414(132580213, +), ADediting_1531697(132516740, +), ADediting_1531698(132519788, +), ADediting_1531699(132547642, +), ADediting_1531700(132554715, +), ADediting_1531701(132554875, +), ADediting_1531702(132554881, +), ADediting_1531703(132578238, +), |
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RNA editing positional annotations for FBRSL1 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_330348 | chr12_132515622_+ | intronic |
| ADediting_330349 | chr12_132515666_+ | intronic |
| ADediting_330350 | chr12_132515667_+ | intronic |
| ADediting_330351 | chr12_132515670_+ | intronic |
| ADediting_330352 | chr12_132515685_+ | intronic |
| ADediting_330353 | chr12_132515690_+ | intronic |
| ADediting_330354 | chr12_132515698_+ | intronic |
| ADediting_330355 | chr12_132515699_+ | intronic |
| ADediting_330356 | chr12_132515704_+ | intronic |
| ADediting_330357 | chr12_132515714_+ | intronic |
| ADediting_330358 | chr12_132515724_+ | intronic |
| ADediting_330359 | chr12_132515737_+ | intronic |
| ADediting_330360 | chr12_132515738_+ | intronic |
| ADediting_330361 | chr12_132515753_+ | intronic |
| ADediting_330362 | chr12_132515757_+ | intronic |
| ADediting_330363 | chr12_132515779_+ | intronic |
| ADediting_330364 | chr12_132515802_+ | intronic |
| ADediting_330365 | chr12_132515811_+ | intronic |
| ADediting_330366 | chr12_132515815_+ | intronic |
| ADediting_330367 | chr12_132516227_+ | intronic |
| ADediting_330368 | chr12_132516230_+ | intronic |
| ADediting_330369 | chr12_132516288_+ | intronic |
| ADediting_330370 | chr12_132516302_+ | intronic |
| ADediting_330371 | chr12_132516324_+ | intronic |
| ADediting_330372 | chr12_132516326_+ | intronic |
| ADediting_330373 | chr12_132516331_+ | intronic |
| ADediting_330374 | chr12_132516340_+ | intronic |
| ADediting_330375 | chr12_132516350_+ | intronic |
| ADediting_330376 | chr12_132516351_+ | intronic |
| ADediting_330377 | chr12_132516359_+ | intronic |
| ADediting_330378 | chr12_132516365_+ | intronic |
| ADediting_330379 | chr12_132516368_+ | intronic |
| ADediting_330380 | chr12_132516382_+ | intronic |
| ADediting_330381 | chr12_132516407_+ | intronic |
| ADediting_330382 | chr12_132516447_+ | intronic |
| ADediting_330383 | chr12_132551285_+ | ncRNA_exonic |
| ADediting_330384 | chr12_132554707_+ | ncRNA_exonic |
| ADediting_330385 | chr12_132554733_+ | ncRNA_exonic |
| ADediting_330386 | chr12_132554746_+ | ncRNA_exonic |
| ADediting_330387 | chr12_132554797_+ | ncRNA_exonic |
| ADediting_330388 | chr12_132554800_+ | ncRNA_exonic |
| ADediting_330389 | chr12_132554824_+ | ncRNA_exonic |
| ADediting_330390 | chr12_132554826_+ | ncRNA_exonic |
| ADediting_330391 | chr12_132554827_+ | ncRNA_exonic |
| ADediting_330392 | chr12_132554867_+ | ncRNA_exonic |
| ADediting_330393 | chr12_132554868_+ | ncRNA_exonic |
| ADediting_330394 | chr12_132554888_+ | ncRNA_exonic |
| ADediting_330395 | chr12_132554912_+ | ncRNA_exonic |
| ADediting_330396 | chr12_132554930_+ | ncRNA_exonic |
| ADediting_330397 | chr12_132559431_+ | intronic |
| ADediting_330398 | chr12_132559455_+ | intronic |
| ADediting_330399 | chr12_132559456_+ | intronic |
| ADediting_330400 | chr12_132559466_+ | intronic |
| ADediting_330401 | chr12_132559491_+ | intronic |
| ADediting_330402 | chr12_132559521_+ | intronic |
| ADediting_330403 | chr12_132559533_+ | intronic |
| ADediting_330404 | chr12_132559547_+ | intronic |
| ADediting_330405 | chr12_132559557_+ | intronic |
| ADediting_330406 | chr12_132559558_+ | intronic |
| ADediting_330407 | chr12_132559602_+ | intronic |
| ADediting_330408 | chr12_132559636_+ | intronic |
| ADediting_330409 | chr12_132559637_+ | intronic |
| ADediting_330410 | chr12_132559649_+ | intronic |
| ADediting_330411 | chr12_132559663_+ | intronic |
| ADediting_330412 | chr12_132566811_+ | intronic |
| ADediting_330413 | chr12_132571792_+ | intronic |
| ADediting_330414 | chr12_132580213_+ | intronic |
| ADediting_1531697 | chr12_132516740_+ | intronic |
| ADediting_1531698 | chr12_132519788_+ | intronic |
| ADediting_1531699 | chr12_132547642_+ | intronic |
| ADediting_1531700 | chr12_132554715_+ | ncRNA_exonic |
| ADediting_1531701 | chr12_132554875_+ | ncRNA_exonic |
| ADediting_1531702 | chr12_132554881_+ | ncRNA_exonic |
| ADediting_1531703 | chr12_132578238_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_330348 | chr12_132515622_+ | SINE | Alu | Name=AluSz |
| ADediting_330349 | chr12_132515666_+ | SINE | Alu | Name=AluSz |
| ADediting_330350 | chr12_132515667_+ | SINE | Alu | Name=AluSz |
| ADediting_330351 | chr12_132515670_+ | SINE | Alu | Name=AluSz |
| ADediting_330352 | chr12_132515685_+ | SINE | Alu | Name=AluSz |
| ADediting_330353 | chr12_132515690_+ | SINE | Alu | Name=AluSz |
| ADediting_330354 | chr12_132515698_+ | SINE | Alu | Name=AluSz |
| ADediting_330355 | chr12_132515699_+ | SINE | Alu | Name=AluSz |
| ADediting_330356 | chr12_132515704_+ | SINE | Alu | Name=AluSz |
| ADediting_330357 | chr12_132515714_+ | SINE | Alu | Name=AluSz |
| ADediting_330358 | chr12_132515724_+ | SINE | Alu | Name=AluSz |
| ADediting_330359 | chr12_132515737_+ | SINE | Alu | Name=AluSz |
| ADediting_330360 | chr12_132515738_+ | SINE | Alu | Name=AluSz |
| ADediting_330361 | chr12_132515753_+ | SINE | Alu | Name=AluSz |
| ADediting_330362 | chr12_132515757_+ | SINE | Alu | Name=AluSz |
| ADediting_330363 | chr12_132515779_+ | SINE | Alu | Name=AluSz |
| ADediting_330364 | chr12_132515802_+ | SINE | Alu | Name=AluSz |
| ADediting_330365 | chr12_132515811_+ | SINE | Alu | Name=AluSz |
| ADediting_330366 | chr12_132515815_+ | SINE | Alu | Name=AluSz |
| ADediting_330367 | chr12_132516227_+ | SINE | Alu | Name=AluSx |
| ADediting_330368 | chr12_132516230_+ | SINE | Alu | Name=AluSx |
| ADediting_330369 | chr12_132516288_+ | SINE | Alu | Name=AluSx |
| ADediting_330370 | chr12_132516302_+ | SINE | Alu | Name=AluSx |
| ADediting_330371 | chr12_132516324_+ | SINE | Alu | Name=AluSx |
| ADediting_330372 | chr12_132516326_+ | SINE | Alu | Name=AluSx |
| ADediting_330373 | chr12_132516331_+ | SINE | Alu | Name=AluSx |
| ADediting_330374 | chr12_132516340_+ | SINE | Alu | Name=AluSx |
| ADediting_330375 | chr12_132516350_+ | SINE | Alu | Name=AluSx |
| ADediting_330376 | chr12_132516351_+ | SINE | Alu | Name=AluSx |
| ADediting_330377 | chr12_132516359_+ | SINE | Alu | Name=AluSx |
| ADediting_330378 | chr12_132516365_+ | SINE | Alu | Name=AluSx |
| ADediting_330379 | chr12_132516368_+ | SINE | Alu | Name=AluSx |
| ADediting_330380 | chr12_132516382_+ | SINE | Alu | Name=AluSx |
| ADediting_330381 | chr12_132516407_+ | SINE | Alu | Name=AluSx |
| ADediting_330382 | chr12_132516447_+ | SINE | Alu | Name=AluSx |
| ADediting_330384 | chr12_132554707_+ | SINE | Alu | Name=AluSx |
| ADediting_330385 | chr12_132554733_+ | SINE | Alu | Name=AluSx |
| ADediting_330386 | chr12_132554746_+ | SINE | Alu | Name=AluSx |
| ADediting_330387 | chr12_132554797_+ | SINE | Alu | Name=AluSx |
| ADediting_330388 | chr12_132554800_+ | SINE | Alu | Name=AluSx |
| ADediting_330389 | chr12_132554824_+ | SINE | Alu | Name=AluSx |
| ADediting_330390 | chr12_132554826_+ | SINE | Alu | Name=AluSx |
| ADediting_330391 | chr12_132554827_+ | SINE | Alu | Name=AluSx |
| ADediting_330392 | chr12_132554867_+ | SINE | Alu | Name=AluSx |
| ADediting_330393 | chr12_132554868_+ | SINE | Alu | Name=AluSx |
| ADediting_330394 | chr12_132554888_+ | SINE | Alu | Name=AluSx |
| ADediting_330395 | chr12_132554912_+ | SINE | Alu | Name=AluSx |
| ADediting_330396 | chr12_132554930_+ | SINE | Alu | Name=AluSx |
| ADediting_330397 | chr12_132559431_+ | SINE | Alu | Name=AluJb |
| ADediting_330398 | chr12_132559455_+ | SINE | Alu | Name=AluJb |
| ADediting_330399 | chr12_132559456_+ | SINE | Alu | Name=AluJb |
| ADediting_330400 | chr12_132559466_+ | SINE | Alu | Name=AluJb |
| ADediting_330401 | chr12_132559491_+ | SINE | Alu | Name=AluJb |
| ADediting_330402 | chr12_132559521_+ | SINE | Alu | Name=AluJb |
| ADediting_330403 | chr12_132559533_+ | SINE | Alu | Name=AluJb |
| ADediting_330404 | chr12_132559547_+ | SINE | Alu | Name=AluJb |
| ADediting_330405 | chr12_132559557_+ | SINE | Alu | Name=AluJb |
| ADediting_330406 | chr12_132559558_+ | SINE | Alu | Name=AluJb |
| ADediting_330407 | chr12_132559602_+ | SINE | Alu | Name=AluJb |
| ADediting_330408 | chr12_132559636_+ | SINE | Alu | Name=AluJb |
| ADediting_330409 | chr12_132559637_+ | SINE | Alu | Name=AluJb |
| ADediting_330410 | chr12_132559649_+ | SINE | Alu | Name=AluJb |
| ADediting_330411 | chr12_132559663_+ | SINE | Alu | Name=AluJb |
| ADediting_330414 | chr12_132580213_+ | SINE | Alu | Name=AluSx |
| ADediting_1531697 | chr12_132516740_+ | SINE | MIR | Name=MIR |
| ADediting_1531698 | chr12_132519788_+ | SINE | Alu | Name=AluSg7 |
| ADediting_1531700 | chr12_132554715_+ | SINE | Alu | Name=AluSx |
| ADediting_1531701 | chr12_132554875_+ | SINE | Alu | Name=AluSx |
| ADediting_1531702 | chr12_132554881_+ | SINE | Alu | Name=AluSx |
| ADediting_1531703 | chr12_132578238_+ | SINE | Alu | Name=AluJb |
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RNA A-to-I editing events in the alternative splicing sites for FBRSL1 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for FBRSL1 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for FBRSL1 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for FBRSL1 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000112787.13 | ENST00000434748.2 | FBRSL1-201 | hsa-miR-5688 | chr12 | 132584461 | 132584467 | 7mer-m8 | 132584447 | 132584468 | 151 | -13.15 |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000112787.13 | ENST00000542061.2 | FBRSL1-204 | hsa-miR-5688 | chr12 | 132510597 | 132510603 | 7mer-m8 | 132510583 | 132510604 | 152 | -17.7 |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000112787.13 | ENST00000650108.1 | FBRSL1-208 | hsa-miR-5688 | chr12 | 132584461 | 132584467 | 7mer-m8 | 132584447 | 132584468 | 151 | -13.15 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000112787.13 | ENST00000542061.2 | FBRSL1-204 | hsa-miR-151a-3p | chr12 | 132511065 | 132511071 | 7mer-m8 | 132511052 | 132511072 | 162 | -25.32 |
| ADediting_1535953 | chr14_101045971_+ | ENSG00000112787.13 | ENST00000542061.2 | FBRSL1-204 | hsa-miR-381-3p | chr12 | 132510868 | 132510874 | 7mer-m8 | 132510854 | 132510875 | 156 | -17.35 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000112787.13 | ENST00000434748.2 | FBRSL1-201 | hsa-miR-4775 | chr12 | 132584851 | 132584857 | 7mer-m8 | 132584837 | 132584858 | 158 | -6.74 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000112787.13 | ENST00000650108.1 | FBRSL1-208 | hsa-miR-4775 | chr12 | 132584851 | 132584857 | 7mer-m8 | 132584837 | 132584858 | 158 | -6.74 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000112787.13 | ENST00000434748.2 | FBRSL1-201 | hsa-miR-5688 | chr12 | 132584341 | 132584347 | 7mer-m8 | 132584330 | 132584348 | 144 | -9.57 |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000112787.13 | ENST00000434748.2 | FBRSL1-201 | hsa-miR-5688 | chr12 | 132585121 | 132585127 | 7mer-m8 | 132585107 | 132585128 | 145 | -10.22 |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000112787.13 | ENST00000650108.1 | FBRSL1-208 | hsa-miR-5688 | chr12 | 132584341 | 132584347 | 7mer-m8 | 132584330 | 132584348 | 144 | -9.57 |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000112787.13 | ENST00000650108.1 | FBRSL1-208 | hsa-miR-5688 | chr12 | 132585121 | 132585127 | 7mer-m8 | 132585107 | 132585128 | 145 | -10.22 |
| ADediting_496066 | chr15_66496985_- | ENSG00000112787.13 | ENST00000434748.2 | FBRSL1-201 | hsa-miR-4512 | chr12 | 132584919 | 132584925 | 7mer-m8 | 132584905 | 132584926 | 140 | -17.22 |
| ADediting_496066 | chr15_66496985_- | ENSG00000112787.13 | ENST00000542061.2 | FBRSL1-204 | hsa-miR-4512 | chr12 | 132511071 | 132511077 | 7mer-m8 | 132511056 | 132511078 | 154 | -24.44 |
| ADediting_496066 | chr15_66496985_- | ENSG00000112787.13 | ENST00000542061.2 | FBRSL1-204 | hsa-miR-4512 | chr12 | 132511769 | 132511775 | 7mer-m8 | 132511755 | 132511776 | 140 | -12.37 |
| ADediting_496066 | chr15_66496985_- | ENSG00000112787.13 | ENST00000650108.1 | FBRSL1-208 | hsa-miR-4512 | chr12 | 132584919 | 132584925 | 7mer-m8 | 132584905 | 132584926 | 140 | -17.22 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for FBRSL1 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for FBRSL1 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_1531702 | chr12_132554881_+ | 0.0305339411892401 | 0.17670189616019 | 4.92634193949849e-05 | 0.325095022687683 | 0.000340563646330576 | 0.288658006663657 |
| DLPFC | ADediting_330355 | chr12_132515699_+ | 0.343521249106315 | -0.0539779134959416 | 0.00416591842724198 | -0.162314261952677 | 7.07715308042464e-12 | 0.376498907887138 |
| DLPFC | ADediting_330366 | chr12_132515815_+ | 0.188172057168843 | -0.0749417135667319 | 0.0139043594299801 | -0.139582300475528 | 6.65506589569971e-09 | 0.321877370272563 |
| DLPFC | ADediting_330368 | chr12_132516230_+ | 0.59990306686211 | -0.0299060134996999 | 0.0233083143703054 | -0.12881639855315 | 5.29383513016906e-08 | 0.30296704871337 |
| DLPFC | ADediting_330378 | chr12_132516365_+ | 0.99086647604527 | -0.00065280714994183 | 0.140367967961282 | -0.0839327905902942 | 2.58450715856163e-08 | 0.309656626537946 |
| DLPFC | ADediting_330384 | chr12_132554707_+ | 0.419358394013984 | 0.0460265225902715 | 0.0879603263030216 | -0.0970720220508398 | 3.46445790561917e-10 | 0.34675698253176 |
| CER | ADediting_330384 | chr12_132554707_+ | 6.02944615510763e-06 | 0.360037328533176 | 3.00873422673864e-09 | 0.460624168013665 | 0.000604647520457562 | 0.2768416689903 |
| CER | ADediting_330385 | chr12_132554733_+ | 0.00478077595534349 | 0.229212274137632 | 0.000125822310590534 | 0.308015155758738 | 0.000394873737400746 | 0.285661378450434 |
| CER | ADediting_330386 | chr12_132554746_+ | 0.000201336653254312 | 0.299044968316452 | 2.11685388378134e-07 | 0.408451534211596 | 0.000140608445106535 | 0.305921002248479 |
| CER | ADediting_330388 | chr12_132554800_+ | 0.0033760887761404 | 0.237879573630037 | 4.51565280368261e-05 | 0.326629753098808 | 0.0109009924928268 | 0.207338837990887 |
| CER | ADediting_330389 | chr12_132554824_+ | 0.00365765252756669 | 0.235910739353134 | 5.08461656643843e-06 | 0.362698391036795 | 0.00545254407881868 | 0.225854763907953 |
| TCX | ADediting_330389 | chr12_132554824_+ | 0.0907600840030423 | 0.138594479601359 | 0.58510292743262 | -0.0449296563938063 | 6.06905270707908e-06 | 0.35993462558669 |
| CER | ADediting_330390 | chr12_132554826_+ | 0.00448458338780173 | 0.230828888144001 | 2.3241985768227e-05 | 0.338078041573421 | 0.00612017738220061 | 0.222866072846728 |
| TCX | ADediting_330390 | chr12_132554826_+ | 0.296864018343405 | 0.0857357255621668 | 0.56308187919835 | -0.0475868688023532 | 0.000110549309793795 | 0.310434657962533 |
| TCX | ADediting_330393 | chr12_132554868_+ | 0.144699363939607 | 0.119659729718129 | 0.212772455222314 | -0.102322406148379 | 3.67755359751102e-07 | 0.400980663727107 |
| CER | ADediting_330394 | chr12_132554888_+ | 0.00516880699818657 | 0.227225055344375 | 4.18321690562254e-06 | 0.365716231239254 | 0.0664981200355485 | 0.150236521981918 |
| CER | ADediting_330396 | chr12_132554930_+ | 0.00386042991468937 | 0.234575650216387 | 0.00014039113032154 | 0.305950262693005 | 0.00796841888561863 | 0.215894498546249 |
| TCX | ADediting_330396 | chr12_132554930_+ | 0.178422969708919 | 0.110457466315447 | 0.635797177332723 | 0.0389792826311022 | 0.00012896500105239 | 0.307551524659621 |
| DLPFC | ADediting_330397 | chr12_132559431_+ | 0.194704138006302 | 0.0738503369153574 | 0.409080107198136 | -0.0470501170216275 | 5.87863460337657e-12 | 0.377843677443928 |
| DLPFC | ADediting_330399 | chr12_132559456_+ | 0.545257367579612 | 0.0344840799778792 | 0.05910398634244 | -0.107321948543576 | 5.79123780228787e-21 | 0.499454078936086 |
| TCX | ADediting_330399 | chr12_132559456_+ | 0.519905253768371 | 0.0529469112140018 | 0.415435041115037 | -0.0669783378539513 | 0.000144575582352608 | 0.305394124502677 |
| CER | ADediting_330402 | chr12_132559521_+ | 0.0949476964225147 | 0.136845819953903 | 1.55912017257856e-05 | 0.344748587153954 | 0.0178386526929356 | 0.193214012176874 |
| CER | ADediting_330410 | chr12_132559649_+ | 0.00806469587748851 | 0.215572293434383 | 1.93463339782815e-06 | 0.377353037716882 | 0.00239902727579485 | 0.246106401339307 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 5.27568679809895e-16 | 0.438572663990496 | 1.04022369002274e-16 | 0.448006221538798 | 6.00872795424428e-21 | 0.49927585016428 |
| CER | 2.50582269997189e-07 | 0.406189077678082 | 1.3341657961714e-12 | 0.537423328512446 | 0.00891987899815762 | 0.212850842556369 |
| TCX | 5.43354024717846e-08 | 0.426107493984429 | 8.43694152566001e-10 | 0.474656418133836 | 0.00255454100657159 | 0.24461412676953 |
| FP | 0.969940846655197 | -0.00284445542891684 | 3.59486514172361e-05 | -0.304472308759749 | 2.89348380271e-06 | 0.342403289294872 |
| IFG | 0.00078081181575504 | 0.627767322844183 | 0.00161457673804194 | 0.597405646446471 | 9.15149531107378e-05 | 0.70211221116622 |
| STG | 0.73866913446178 | -0.0369416199327625 | 0.0108464795100381 | -0.276663682158174 | 0.000295498357848049 | 0.385299998438393 |
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Relation with AD stages for FBRSL1 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_330384 | chr12_132554707_+ | 4.08645493063753e-06 | 0.426866476414185 |
| CER | ADediting_330385 | chr12_132554733_+ | 2.15014184945774e-05 | 0.396553384344991 |
| CER | ADediting_330386 | chr12_132554746_+ | 5.02176522678361e-06 | 0.423259676786248 |
| CER | ADediting_330387 | chr12_132554797_+ | 0.000553139636412024 | 0.326946093758185 |
| CER | ADediting_330388 | chr12_132554800_+ | 2.26168995826827e-06 | 0.436994473714781 |
| CER | ADediting_330389 | chr12_132554824_+ | 1.1345588079816e-05 | 0.408575078978004 |
| CER | ADediting_330390 | chr12_132554826_+ | 6.05540099906604e-06 | 0.419947893755316 |
| CER | ADediting_330393 | chr12_132554868_+ | 1.84590498904907e-05 | 0.399464783831787 |
| CER | ADediting_330397 | chr12_132559431_+ | 6.81387103515825e-05 | 0.373608662458204 |
| CER | ADediting_330398 | chr12_132559455_+ | 1.44357406128974e-05 | 0.404099729333053 |
| CER | ADediting_330399 | chr12_132559456_+ | 7.70257875277943e-05 | 0.371066273320177 |
| CER | ADediting_330402 | chr12_132559521_+ | 0.000584597227339077 | 0.325609149886164 |
| CER | ADediting_330403 | chr12_132559533_+ | 0.000311122810958572 | 0.340507439326383 |
| CER | ADediting_330405 | chr12_132559557_+ | 4.06722793522592e-05 | 0.38408460727633 |
| CER | ADediting_330407 | chr12_132559602_+ | 0.000353964608518973 | 0.337520395767005 |
| CER | ADediting_330409 | chr12_132559637_+ | 0.000307303157590575 | 0.340791894141217 |
| CER | ADediting_330410 | chr12_132559649_+ | 3.40610272554366e-06 | 0.430019238728638 |
| CER | ADediting_1531702 | chr12_132554881_+ | 0.000331452395618811 | 0.339045629075741 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 0.000854019770016701 | 0.316280012412741 |
| TCX | 0.000456755113115298 | 0.334530599341244 |
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RelatedDrugs for FBRSL1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for FBRSL1 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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