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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for STRIP2

check button Gene summary
Gene informationGene symbol

STRIP2

Gene ID

57464

Gene namestriatin interacting protein 2
SynonymsFAM40B|FAR11B
Cytomap

7q32.1

Type of geneprotein-coding
Descriptionstriatin-interacting protein 2FAR11 factor arrest 11 homolog Bfamily with sequence similarity 40, member Bhomolog of yeast FAR11 protein 2protein FAM40B
Modification date20200313
UniProtAcc

Q9ULQ0,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for STRIP2

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_1303197(129437180, +), ADediting_1303198(129437357, +), ADediting_1303199(129437423, +), ADediting_1303200(129437945, +), ADediting_1303201(129441589, +), ADediting_1303202(129441638, +), ADediting_1303203(129441661, +), ADediting_1303204(129441673, +), ADediting_1303205(129441802, +), ADediting_1303206(129441807, +), ADediting_1303207(129441876, +), ADediting_1303208(129441878, +), ADediting_1303209(129441890, +), ADediting_1303210(129441958, +), ADediting_1303211(129441972, +), ADediting_1303212(129441973, +), ADediting_1303213(129441981, +), ADediting_1303214(129441996, +), ADediting_1303215(129442029, +), ADediting_1303216(129442127, +), ADediting_1303217(129442174, +), ADediting_1303218(129442175, +), ADediting_1303219(129442208, +), ADediting_1303220(129443084, +), ADediting_1303221(129443102, +), ADediting_1303222(129443110, +), ADediting_1303223(129443118, +), ADediting_1303224(129443119, +), ADediting_1303225(129443120, +), ADediting_1303226(129443135, +), ADediting_1303227(129443141, +), ADediting_1303228(129443142, +), ADediting_1303229(129443157, +), ADediting_1303230(129443173, +), ADediting_1303231(129443179, +), ADediting_1303232(129443292, +), ADediting_1303233(129474274, +), ADediting_1303234(129478445, +), ADediting_1303235(129479073, +), ADediting_1303236(129479074, +), ADediting_1303237(129479085, +), ADediting_1303238(129479113, +), ADediting_1303239(129479151, +), ADediting_1303240(129479153, +), ADediting_1303241(129479167, +), ADediting_1303242(129479180, +), ADediting_1303243(129479186, +), ADediting_1303244(129479194, +), ADediting_1303245(129479258, +), ADediting_1303246(129479590, +), ADediting_1303247(129479607, +), ADediting_1303248(129479702, +), ADediting_1303249(129479713, +), ADediting_1303250(129479760, +), ADediting_1303251(129481230, +), ADediting_1303252(129482073, +), ADediting_1303253(129487036, +), ADediting_1303254(129487058, +), ADediting_1303255(129487069, +), ADediting_1303256(129487070, +), ADediting_1303257(129487075, +), ADediting_1303258(129487094, +), ADediting_1303259(129487153, +), ADediting_1303260(129487195, +), ADediting_1303261(129487201, +), ADediting_1303262(129487204, +), ADediting_1303263(129487220, +), ADediting_1303264(129488024, +), ADediting_1303265(129488107, +), ADediting_1303266(129488121, +), ADediting_1303267(129488131, +), ADediting_1303268(129488146, +), ADediting_1303269(129488148, +), ADediting_1303270(129488149, +), ADediting_1303271(129488151, +), ADediting_1303272(129488152, +), ADediting_1585875(129487143, +),

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RNA editing positional annotations for STRIP2 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_1303197chr7_129437180_+intronic
ADediting_1303198chr7_129437357_+intronic
ADediting_1303199chr7_129437423_+intronic
ADediting_1303200chr7_129437945_+intronic
ADediting_1303201chr7_129441589_+intronic
ADediting_1303202chr7_129441638_+intronic
ADediting_1303203chr7_129441661_+intronic
ADediting_1303204chr7_129441673_+intronic
ADediting_1303205chr7_129441802_+intronic
ADediting_1303206chr7_129441807_+intronic
ADediting_1303207chr7_129441876_+intronic
ADediting_1303208chr7_129441878_+intronic
ADediting_1303209chr7_129441890_+intronic
ADediting_1303210chr7_129441958_+intronic
ADediting_1303211chr7_129441972_+intronic
ADediting_1303212chr7_129441973_+intronic
ADediting_1303213chr7_129441981_+intronic
ADediting_1303214chr7_129441996_+intronic
ADediting_1303215chr7_129442029_+intronic
ADediting_1303216chr7_129442127_+intronic
ADediting_1303217chr7_129442174_+intronic
ADediting_1303218chr7_129442175_+intronic
ADediting_1303219chr7_129442208_+intronic
ADediting_1303220chr7_129443084_+intronic
ADediting_1303221chr7_129443102_+intronic
ADediting_1303222chr7_129443110_+intronic
ADediting_1303223chr7_129443118_+intronic
ADediting_1303224chr7_129443119_+intronic
ADediting_1303225chr7_129443120_+intronic
ADediting_1303226chr7_129443135_+intronic
ADediting_1303227chr7_129443141_+intronic
ADediting_1303228chr7_129443142_+intronic
ADediting_1303229chr7_129443157_+intronic
ADediting_1303230chr7_129443173_+intronic
ADediting_1303231chr7_129443179_+intronic
ADediting_1303232chr7_129443292_+intronic
ADediting_1303233chr7_129474274_+intronic
ADediting_1303234chr7_129478445_+intronic
ADediting_1303235chr7_129479073_+intronic
ADediting_1303236chr7_129479074_+intronic
ADediting_1303237chr7_129479085_+intronic
ADediting_1303238chr7_129479113_+intronic
ADediting_1303239chr7_129479151_+intronic
ADediting_1303240chr7_129479153_+intronic
ADediting_1303241chr7_129479167_+intronic
ADediting_1303242chr7_129479180_+intronic
ADediting_1303243chr7_129479186_+intronic
ADediting_1303244chr7_129479194_+intronic
ADediting_1303245chr7_129479258_+intronic
ADediting_1303246chr7_129479590_+intronic
ADediting_1303247chr7_129479607_+intronic
ADediting_1303248chr7_129479702_+intronic
ADediting_1303249chr7_129479713_+intronic
ADediting_1303250chr7_129479760_+intronic
ADediting_1303251chr7_129481230_+intronic
ADediting_1303252chr7_129482073_+intronic
ADediting_1303253chr7_129487036_+UTR3
ADediting_1303254chr7_129487058_+UTR3
ADediting_1303255chr7_129487069_+UTR3
ADediting_1303256chr7_129487070_+UTR3
ADediting_1303257chr7_129487075_+UTR3
ADediting_1303258chr7_129487094_+UTR3
ADediting_1303259chr7_129487153_+UTR3
ADediting_1303260chr7_129487195_+UTR3
ADediting_1303261chr7_129487201_+UTR3
ADediting_1303262chr7_129487204_+UTR3
ADediting_1303263chr7_129487220_+UTR3
ADediting_1303264chr7_129488024_+UTR3
ADediting_1303265chr7_129488107_+UTR3
ADediting_1303266chr7_129488121_+UTR3
ADediting_1303267chr7_129488131_+UTR3
ADediting_1303268chr7_129488146_+UTR3
ADediting_1303269chr7_129488148_+UTR3
ADediting_1303270chr7_129488149_+UTR3
ADediting_1303271chr7_129488151_+UTR3
ADediting_1303272chr7_129488152_+UTR3
ADediting_1585875chr7_129487143_+UTR3

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_1303197chr7_129437180_+SINEAluName=AluJr
ADediting_1303198chr7_129437357_+SINEAluName=AluJr
ADediting_1303199chr7_129437423_+SINEAluName=AluJr
ADediting_1303200chr7_129437945_+SINEAluName=AluY
ADediting_1303201chr7_129441589_+SINEAluName=AluJb
ADediting_1303202chr7_129441638_+SINEAluName=AluJb
ADediting_1303203chr7_129441661_+SINEAluName=AluJb
ADediting_1303204chr7_129441673_+SINEAluName=AluJb
ADediting_1303205chr7_129441802_+SINEAluName=AluJb
ADediting_1303206chr7_129441807_+SINEAluName=AluJb
ADediting_1303207chr7_129441876_+SINEAluName=AluJb
ADediting_1303208chr7_129441878_+SINEAluName=AluJb
ADediting_1303209chr7_129441890_+SINEAluName=AluJb
ADediting_1303210chr7_129441958_+SINEAluName=AluSx
ADediting_1303211chr7_129441972_+SINEAluName=AluSx
ADediting_1303212chr7_129441973_+SINEAluName=AluSx
ADediting_1303213chr7_129441981_+SINEAluName=AluSx
ADediting_1303214chr7_129441996_+SINEAluName=AluSx
ADediting_1303215chr7_129442029_+SINEAluName=AluSx
ADediting_1303216chr7_129442127_+SINEAluName=AluSx
ADediting_1303217chr7_129442174_+SINEAluName=AluSx
ADediting_1303218chr7_129442175_+SINEAluName=AluSx
ADediting_1303219chr7_129442208_+SINEAluName=AluSx
ADediting_1303220chr7_129443084_+SINEAluName=AluJr4
ADediting_1303221chr7_129443102_+SINEAluName=AluJr4
ADediting_1303222chr7_129443110_+SINEAluName=AluJr4
ADediting_1303223chr7_129443118_+SINEAluName=AluJr4
ADediting_1303224chr7_129443119_+SINEAluName=AluJr4
ADediting_1303225chr7_129443120_+SINEAluName=AluJr4
ADediting_1303226chr7_129443135_+SINEAluName=AluJr4
ADediting_1303227chr7_129443141_+SINEAluName=AluJr4
ADediting_1303228chr7_129443142_+SINEAluName=AluJr4
ADediting_1303229chr7_129443157_+SINEAluName=AluJr4
ADediting_1303230chr7_129443173_+SINEAluName=AluJr4
ADediting_1303231chr7_129443179_+SINEAluName=AluJr4
ADediting_1303232chr7_129443292_+SINEAluName=AluJr4
ADediting_1303233chr7_129474274_+SINEAluName=AluJb
ADediting_1303234chr7_129478445_+SINEAluName=AluSx1
ADediting_1303235chr7_129479073_+SINEAluName=AluSp
ADediting_1303236chr7_129479074_+SINEAluName=AluSp
ADediting_1303237chr7_129479085_+SINEAluName=AluSp
ADediting_1303238chr7_129479113_+SINEAluName=AluSp
ADediting_1303239chr7_129479151_+SINEAluName=AluSp
ADediting_1303240chr7_129479153_+SINEAluName=AluSp
ADediting_1303241chr7_129479167_+SINEAluName=AluSp
ADediting_1303242chr7_129479180_+SINEAluName=AluSp
ADediting_1303243chr7_129479186_+SINEAluName=AluSp
ADediting_1303244chr7_129479194_+SINEAluName=AluSp
ADediting_1303245chr7_129479258_+SINEAluName=AluSp
ADediting_1303246chr7_129479590_+SINEAluName=AluSq2
ADediting_1303247chr7_129479607_+SINEAluName=AluSq2
ADediting_1303248chr7_129479702_+SINEAluName=AluSq2
ADediting_1303249chr7_129479713_+SINEAluName=AluSq2
ADediting_1303250chr7_129479760_+SINEAluName=AluSq2
ADediting_1303251chr7_129481230_+SINEAluName=AluSg
ADediting_1303252chr7_129482073_+SINEAluName=AluSx1
ADediting_1303253chr7_129487036_+SINEAluName=AluSq2
ADediting_1303254chr7_129487058_+SINEAluName=AluSq2
ADediting_1303255chr7_129487069_+SINEAluName=AluSq2
ADediting_1303256chr7_129487070_+SINEAluName=AluSq2
ADediting_1303257chr7_129487075_+SINEAluName=AluSq2
ADediting_1303258chr7_129487094_+SINEAluName=AluSq2
ADediting_1303259chr7_129487153_+SINEAluName=AluSq2
ADediting_1303260chr7_129487195_+SINEAluName=AluSq2
ADediting_1303261chr7_129487201_+SINEAluName=AluSq2
ADediting_1303262chr7_129487204_+SINEAluName=AluSq2
ADediting_1303263chr7_129487220_+SINEAluName=AluSq2
ADediting_1303265chr7_129488107_+SINEAluName=AluSq
ADediting_1303266chr7_129488121_+SINEAluName=AluSq
ADediting_1303267chr7_129488131_+SINEAluName=AluSq
ADediting_1303268chr7_129488146_+SINEAluName=AluSq
ADediting_1303269chr7_129488148_+SINEAluName=AluSq
ADediting_1303270chr7_129488149_+SINEAluName=AluSq
ADediting_1303271chr7_129488151_+SINEAluName=AluSq
ADediting_1303272chr7_129488152_+SINEAluName=AluSq
ADediting_1585875chr7_129487143_+SINEAluName=AluSq2

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RNA A-to-I editing events in the alternative splicing sites for STRIP2

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for STRIP2

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for STRIP2

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for STRIP2

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1303253chr7_129487036_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-340-3pchr71294870301294870378mer-1a129487016129487037146-18.22
ADediting_1303253chr7_129487036_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-6827-3pchr71294870301294870378mer-1a129487017129487037140-14.67
ADediting_1303254chr7_129487058_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-3187-5pchr71294870511294870577mer-m8129487037129487058159-29.61
ADediting_1303254chr7_129487058_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-5189-5pchr71294870511294870577mer-m8129487033129487058150-22.93
ADediting_1303254chr7_129487058_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-612chr71294870511294870577mer-m8129487033129487058149-22.25
ADediting_1303254chr7_129487058_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-661chr71294870531294870597mer-m8129487037129487060143-21.35
ADediting_1303254chr7_129487058_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-6849-3pchr71294870561294870638mer-1a129487043129487063150-17.05
ADediting_1303254chr7_129487058_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-6860chr71294870511294870577mer-m8129487039129487058145-20.24
ADediting_1303254chr7_129487058_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-939-3pchr71294870521294870587mer-m8129487039129487059140-15.63
ADediting_1303256chr7_129487070_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-324-3pchr71294870661294870727mer-m8129487049129487073150-21.96
ADediting_1303256chr7_129487070_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-4252chr71294870671294870748mer-1a129487054129487074149-22.65
ADediting_1303256chr7_129487070_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-4793-3pchr71294870631294870697mer-m8129487048129487070153-19.63
ADediting_1303258chr7_129487094_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-17-3pchr71294870871294870937mer-m8129487073129487094150-17.84
ADediting_1303258chr7_129487094_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-485-5pchr71294870911294870977mer-m8129487078129487098153-19.07
ADediting_1303258chr7_129487094_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-6884-5pchr71294870911294870977mer-m8129487075129487098150-23.9
ADediting_1303261chr7_129487201_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-4421chr71294871991294872057mer-m8129487185129487206154-16.19
ADediting_1303261chr7_129487201_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-4684-5pchr71294871951294872017mer-m8129487180129487202159-15.66
ADediting_1303261chr7_129487201_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-5699-3pchr71294871991294872057mer-m8129487185129487206153-17.34
ADediting_1303261chr7_129487201_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-593-3pchr71294871971294872037mer-1a129487185129487203140-19.02
ADediting_1303261chr7_129487201_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-6818-3pchr71294871971294872037mer-m8129487183129487204140-12.56
ADediting_1303263chr7_129487220_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-3190-5pchr71294872181294872247mer-m8129487206129487225147-18.34
ADediting_1303263chr7_129487220_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-548schr71294872171294872237mer-m8129487200129487224143-15.64
ADediting_1303264chr7_129488024_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-4676-5pchr71294880201294880267mer-m8129488004129488027150-16.87
ADediting_1303264chr7_129488024_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-575chr71294880201294880267mer-m8129488008129488027147-19.19
ADediting_1303266chr7_129488121_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-564chr71294881191294881257mer-1a129488107129488125143-19.46
ADediting_1303270chr7_129488149_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-367-5pchr71294881421294881487mer-m8129488127129488149148-13.32
ADediting_1303270chr7_129488149_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-7152-5pchr71294881451294881517mer-m8129488131129488152150-14.04
ADediting_1303272chr7_129488152_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-6812-3pchr71294881471294881548mer-1a129488134129488154140-18.1
ADediting_1585875chr7_129487143_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-6769a-3pchr71294871391294871457mer-m8129487126129487146140-17.35

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1303253chr7_129487036_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-3664-5pchr71294870331294870397mer-m8129487019129487040153-16.53
ADediting_1303253chr7_129487036_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-6888-3pchr71294870311294870377mer-m8129487018129487038151-14.42
ADediting_1303254chr7_129487058_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-4453chr71294870541294870607mer-m8129487042129487061150-15.12
ADediting_1303254chr7_129487058_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-4538chr71294870541294870607mer-m8129487040129487061151-16.99
ADediting_1303254chr7_129487058_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-635chr71294870521294870587mer-m8129487037129487059151-18.79
ADediting_1303255chr7_129487069_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-25-3pchr71294870641294870707mer-m8129487049129487071154-18.76
ADediting_1303255chr7_129487069_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-32-5pchr71294870641294870707mer-m8129487049129487071145-12.44
ADediting_1303255chr7_129487069_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-363-3pchr71294870641294870707mer-m8129487054129487071146-12.63
ADediting_1303255chr7_129487069_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-7703chr71294870621294870698mer-1a129487047129487069154-19.44
ADediting_1303255chr7_129487069_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-92a-3pchr71294870641294870707mer-m8129487054129487071147-19.71
ADediting_1303255chr7_129487069_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-92b-3pchr71294870641294870707mer-m8129487050129487071150-18.96
ADediting_1303256chr7_129487070_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-25-3pchr71294870641294870707mer-m8129487049129487071154-18.76
ADediting_1303256chr7_129487070_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-32-5pchr71294870641294870707mer-m8129487049129487071145-12.44
ADediting_1303256chr7_129487070_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-363-3pchr71294870641294870707mer-m8129487054129487071146-12.63
ADediting_1303256chr7_129487070_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-92a-3pchr71294870641294870707mer-m8129487054129487071147-19.71
ADediting_1303256chr7_129487070_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-92b-3pchr71294870641294870707mer-m8129487050129487071150-18.96
ADediting_1303258chr7_129487094_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-377-5pchr71294870911294870977mer-m8129487075129487098150-17.59
ADediting_1303258chr7_129487094_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-6086chr71294870911294870977mer-m8129487079129487098150-23.99
ADediting_1303258chr7_129487094_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-6516-5pchr71294870871294870937mer-m8129487069129487094147-15.44
ADediting_1303262chr7_129487204_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-10a-5pchr71294872011294872077mer-m8129487186129487208145-12.2
ADediting_1303262chr7_129487204_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-10b-5pchr71294872011294872077mer-m8129487186129487208140-12.2
ADediting_1303262chr7_129487204_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-6732-3pchr71294872021294872087mer-m8129487188129487209150-14.93
ADediting_1303263chr7_129487220_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-4794chr71294872181294872247mer-m8129487203129487225151-18.19
ADediting_1303263chr7_129487220_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-664a-5pchr71294872181294872247mer-m8129487202129487225141-16.24
ADediting_1303264chr7_129488024_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-554chr71294880181294880247mer-m8129488005129488025144-20.85
ADediting_1303264chr7_129488024_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-8086chr71294880191294880257mer-m8129488005129488026148-14.74
ADediting_1303265chr7_129488107_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-4772-3pchr71294881011294881077mer-m8129488086129488108151-13.75
ADediting_1303268chr7_129488146_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-744-3pchr71294881411294881488mer-1a129488127129488148140-10.2
ADediting_1303269chr7_129488148_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-744-3pchr71294881411294881488mer-1a129488127129488148140-10.2
ADediting_1585875chr7_129487143_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-4267chr71294871411294871477mer-m8129487133129487148149-19.69
ADediting_1585875chr7_129487143_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-4448chr71294871381294871447mer-m8129487126129487145150-23.08
ADediting_1585875chr7_129487143_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-6736-3pchr71294871401294871467mer-m8129487127129487147145-16.09

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337757chr7_5495852_-ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-589-3pchr71294858811294858877mer-m8129485865129485888142-13.85
ADediting_1337757chr7_5495852_-ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-589-3pchr71294865051294865117mer-m8129486492129486512148-21.55
ADediting_1535951chr14_100874558_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-337-3pchr71294866651294866717mer-m8129486651129486672152-15.37

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_843620chr2_207754818_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-4775chr71294864671294864737mer-m8129486453129486474146-2.56
ADediting_843620chr2_207754818_+ENSG00000128578.10ENST00000249344.7STRIP2-201hsa-miR-4775chr71294866191294866257mer-m8129486603129486626155-12.24

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for STRIP2

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000249344.7protein_codingSoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_1303253ENST00000249344.7chr7_129487036_+3753-1663.70-1657.50-1706.00
ADediting_1303254ENST00000249344.7chr7_129487058_+3775-1664.10-1657.50-1706.00
ADediting_1303255ENST00000249344.7chr7_129487069_+3786-1656.80-1657.50-1706.00
ADediting_1303256ENST00000249344.7chr7_129487070_+3787-1663.70-1657.50-1706.00
ADediting_1303257ENST00000249344.7chr7_129487075_+3792-1657.50-1657.50-1706.00
ADediting_1303258ENST00000249344.7chr7_129487094_+3811-1657.50-1657.50-1706.00
ADediting_1585875ENST00000249344.7chr7_129487143_+3860-1663.90-1657.50-1706.00
ADediting_1303259ENST00000249344.7chr7_129487153_+3870-1660.70-1657.50-1706.00
ADediting_1303260ENST00000249344.7chr7_129487195_+3912-1661.80-1657.50-1706.00
ADediting_1303261ENST00000249344.7chr7_129487201_+3918-1657.60-1657.50-1706.00
ADediting_1303262ENST00000249344.7chr7_129487204_+3921-1657.40-1657.50-1706.00
ADediting_1303263ENST00000249344.7chr7_129487220_+3937-1657.20-1657.50-1706.00
ADediting_1303264ENST00000249344.7chr7_129488024_+4741-1664.10-1657.50-1706.00
ADediting_1303265ENST00000249344.7chr7_129488107_+4824-1656.80-1657.50-1706.00
ADediting_1303266ENST00000249344.7chr7_129488121_+4838-1663.30-1657.50-1706.00
ADediting_1303267ENST00000249344.7chr7_129488131_+4848-1657.10-1657.50-1706.00
ADediting_1303268ENST00000249344.7chr7_129488146_+4863-1657.50-1657.50-1706.00
ADediting_1303269ENST00000249344.7chr7_129488148_+4865-1657.20-1657.50-1706.00
ADediting_1303270ENST00000249344.7chr7_129488149_+4866-1657.20-1657.50-1706.00
ADediting_1303271ENST00000249344.7chr7_129488151_+4868-1656.60-1657.50-1706.00
ADediting_1303272ENST00000249344.7chr7_129488152_+4869-1664.20-1657.50-1706.00

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for STRIP2

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
CERADediting_1303257chr7_129487075_+0.0004555126981333010.2827363668066440.0001413092575016990.305826927411890.01517515038418150.1979494176694
CERADediting_1303263chr7_129487220_+0.0007191261271626840.2731676520836983.84849984219287e-060.366996718766780.02454322535159870.18356335903688
DLPFCADediting_1303264chr7_129488024_+1.26083451484202e-080.3161903420410886.9662805124775e-130.3928748753651340.27704634584559-0.0619271251997533

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC1.17730437404431e-750.8170960648855011.3363485169696e-850.8446926528821030.000653626906872920.192543323833918
AC2.80221912284352e-460.7492516841646752.78054689373911e-630.8245552118768690.273059446101958-0.0695845870913877
PCC7.66800329320072e-090.40271944732921.7587943841703e-080.393677209796240.3837306825738140.0633791034414497
CER3.28658197350418e-320.7821327498079281.63357629016665e-170.6232543746651440.4772675657669180.0584681985422256
TCX1.52198158586793e-180.6384062822010492.71850808562297e-350.8044314962060020.00011336007558445-0.309966861011974
FP7.19048497451884e-220.6396772209592651.86332276498057e-320.7425568181959960.2795125931210540.081494722262087
PG4.27985025530469e-180.5797870825980337.49375233198521e-200.6036867057971660.0292383979594799-0.159912034174063
STG0.000115456037904050.408306110514832.85260672430032e-070.5255311905487410.783281112989797-0.0304593847490763

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Relation with AD stages for STRIP2

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
IFGADediting_1303264chr7_129488024_+0.03547133699799280.422303326441651
IFGADediting_1303272chr7_129488152_+0.01130599370490140.497952103823781

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
CER0.001438352450300230.302939659111832

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RelatedDrugs for STRIP2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for STRIP2

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource