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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for SELENON

check button Gene summary
Gene informationGene symbol

SELENON

Gene ID

57190

Gene nameselenoprotein N
SynonymsCFTD|MDRS1|RSMD1|RSS|SELN|SEPN1
Cytomap

1p36.11

Type of geneprotein-coding
Descriptionselenoprotein Nselenoprotein N, 1
Modification date20200328
UniProtAcc

Q9NZV5,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for SELENON

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_87998(25801394, +), ADediting_87999(25801398, +), ADediting_88000(25801403, +), ADediting_88001(25801411, +), ADediting_88002(25801446, +), ADediting_88003(25801451, +), ADediting_88004(25801459, +), ADediting_88005(25801460, +), ADediting_88006(25801465, +), ADediting_88007(25801475, +), ADediting_88008(25801477, +), ADediting_88009(25801482, +), ADediting_88010(25801483, +), ADediting_88011(25801484, +), ADediting_88012(25801485, +), ADediting_88013(25801490, +), ADediting_88014(25801496, +), ADediting_88015(25801499, +), ADediting_88016(25801500, +), ADediting_88017(25801501, +), ADediting_88018(25801502, +), ADediting_88019(25801504, +), ADediting_88020(25801509, +), ADediting_88021(25801510, +), ADediting_88022(25801513, +), ADediting_88023(25801533, +), ADediting_88024(25801539, +), ADediting_88025(25801545, +), ADediting_88026(25801549, +), ADediting_88027(25801575, +), ADediting_88028(25801578, +), ADediting_88029(25801592, +), ADediting_88030(25801642, +), ADediting_88031(25801644, +), ADediting_88032(25801826, +), ADediting_88033(25802030, +), ADediting_88034(25802076, +), ADediting_88035(25802077, +), ADediting_88036(25802108, +), ADediting_88037(25802120, +), ADediting_88038(25802121, +), ADediting_88039(25802130, +), ADediting_88040(25802136, +), ADediting_88041(25802146, +), ADediting_88042(25802152, +), ADediting_88043(25802187, +), ADediting_88044(25802210, +), ADediting_88045(25802211, +), ADediting_88046(25802226, +), ADediting_88047(25802264, +), ADediting_88048(25802396, +), ADediting_88049(25802460, +), ADediting_88050(25802461, +), ADediting_88051(25802474, +), ADediting_88052(25802496, +), ADediting_88053(25802561, +), ADediting_88054(25803584, +), ADediting_88055(25803585, +), ADediting_88056(25803593, +), ADediting_88057(25803597, +), ADediting_88058(25803639, +), ADediting_88059(25803651, +), ADediting_88060(25803664, +), ADediting_88061(25803729, +), ADediting_88062(25803801, +), ADediting_88063(25803802, +), ADediting_88064(25803842, +), ADediting_88065(25803864, +), ADediting_88066(25803886, +), ADediting_88067(25803888, +), ADediting_88068(25803913, +), ADediting_88069(25803923, +), ADediting_88070(25803924, +), ADediting_88071(25803931, +), ADediting_88072(25804880, +), ADediting_88073(25804884, +), ADediting_88074(25804898, +), ADediting_88075(25804917, +), ADediting_88076(25815332, +), ADediting_1518643(25801418, +), ADediting_1518644(25801508, +), ADediting_1518645(25801569, +), ADediting_1518646(25801588, +), ADediting_1518647(25801615, +), ADediting_1518648(25802010, +), ADediting_1518649(25802012, +), ADediting_1518650(25802132, +), ADediting_1518651(25802175, +), ADediting_1518652(25802225, +), ADediting_1518653(25802273, +), ADediting_1518654(25802426, +), ADediting_1518655(25802483, +), ADediting_1518656(25802486, +), ADediting_1518657(25802502, +), ADediting_1518658(25802530, +), ADediting_1518659(25802536, +), ADediting_1518660(25802539, +), ADediting_1518661(25802577, +), ADediting_1518662(25802578, +), ADediting_1518663(25802618, +), ADediting_1518664(25803629, +), ADediting_1518665(25803633, +), ADediting_1518666(25803653, +), ADediting_1518667(25803778, +), ADediting_1518668(25803791, +), ADediting_1518669(25803797, +), ADediting_1518670(25803798, +), ADediting_1518671(25803868, +), ADediting_1518672(25803912, +), ADediting_1600237(25801531, +),

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RNA editing positional annotations for SELENON using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_87998chr1_25801394_+intronic
ADediting_87999chr1_25801398_+intronic
ADediting_88000chr1_25801403_+intronic
ADediting_88001chr1_25801411_+intronic
ADediting_88002chr1_25801446_+intronic
ADediting_88003chr1_25801451_+intronic
ADediting_88004chr1_25801459_+intronic
ADediting_88005chr1_25801460_+intronic
ADediting_88006chr1_25801465_+intronic
ADediting_88007chr1_25801475_+intronic
ADediting_88008chr1_25801477_+intronic
ADediting_88009chr1_25801482_+intronic
ADediting_88010chr1_25801483_+intronic
ADediting_88011chr1_25801484_+intronic
ADediting_88012chr1_25801485_+intronic
ADediting_88013chr1_25801490_+intronic
ADediting_88014chr1_25801496_+intronic
ADediting_88015chr1_25801499_+intronic
ADediting_88016chr1_25801500_+intronic
ADediting_88017chr1_25801501_+intronic
ADediting_88018chr1_25801502_+intronic
ADediting_88019chr1_25801504_+intronic
ADediting_88020chr1_25801509_+intronic
ADediting_88021chr1_25801510_+intronic
ADediting_88022chr1_25801513_+intronic
ADediting_88023chr1_25801533_+intronic
ADediting_88024chr1_25801539_+intronic
ADediting_88025chr1_25801545_+intronic
ADediting_88026chr1_25801549_+intronic
ADediting_88027chr1_25801575_+intronic
ADediting_88028chr1_25801578_+intronic
ADediting_88029chr1_25801592_+intronic
ADediting_88030chr1_25801642_+intronic
ADediting_88031chr1_25801644_+intronic
ADediting_88032chr1_25801826_+intronic
ADediting_88033chr1_25802030_+exonic
ADediting_88034chr1_25802076_+exonic
ADediting_88035chr1_25802077_+exonic
ADediting_88036chr1_25802108_+exonic
ADediting_88037chr1_25802120_+intronic
ADediting_88038chr1_25802121_+intronic
ADediting_88039chr1_25802130_+intronic
ADediting_88040chr1_25802136_+intronic
ADediting_88041chr1_25802146_+intronic
ADediting_88042chr1_25802152_+intronic
ADediting_88043chr1_25802187_+intronic
ADediting_88044chr1_25802210_+intronic
ADediting_88045chr1_25802211_+intronic
ADediting_88046chr1_25802226_+intronic
ADediting_88047chr1_25802264_+intronic
ADediting_88048chr1_25802396_+intronic
ADediting_88049chr1_25802460_+intronic
ADediting_88050chr1_25802461_+intronic
ADediting_88051chr1_25802474_+intronic
ADediting_88052chr1_25802496_+intronic
ADediting_88053chr1_25802561_+intronic
ADediting_88054chr1_25803584_+intronic
ADediting_88055chr1_25803585_+intronic
ADediting_88056chr1_25803593_+intronic
ADediting_88057chr1_25803597_+intronic
ADediting_88058chr1_25803639_+intronic
ADediting_88059chr1_25803651_+intronic
ADediting_88060chr1_25803664_+intronic
ADediting_88061chr1_25803729_+intronic
ADediting_88062chr1_25803801_+intronic
ADediting_88063chr1_25803802_+intronic
ADediting_88064chr1_25803842_+intronic
ADediting_88065chr1_25803864_+intronic
ADediting_88066chr1_25803886_+intronic
ADediting_88067chr1_25803888_+intronic
ADediting_88068chr1_25803913_+intronic
ADediting_88069chr1_25803923_+intronic
ADediting_88070chr1_25803924_+intronic
ADediting_88071chr1_25803931_+intronic
ADediting_88072chr1_25804880_+intronic
ADediting_88073chr1_25804884_+intronic
ADediting_88074chr1_25804898_+intronic
ADediting_88075chr1_25804917_+intronic
ADediting_88076chr1_25815332_+intronic
ADediting_1518643chr1_25801418_+intronic
ADediting_1518644chr1_25801508_+intronic
ADediting_1518645chr1_25801569_+intronic
ADediting_1518646chr1_25801588_+intronic
ADediting_1518647chr1_25801615_+intronic
ADediting_1518648chr1_25802010_+intronic
ADediting_1518649chr1_25802012_+intronic
ADediting_1518650chr1_25802132_+intronic
ADediting_1518651chr1_25802175_+intronic
ADediting_1518652chr1_25802225_+intronic
ADediting_1518653chr1_25802273_+intronic
ADediting_1518654chr1_25802426_+intronic
ADediting_1518655chr1_25802483_+intronic
ADediting_1518656chr1_25802486_+intronic
ADediting_1518657chr1_25802502_+intronic
ADediting_1518658chr1_25802530_+intronic
ADediting_1518659chr1_25802536_+intronic
ADediting_1518660chr1_25802539_+intronic
ADediting_1518661chr1_25802577_+intronic
ADediting_1518662chr1_25802578_+intronic
ADediting_1518663chr1_25802618_+intronic
ADediting_1518664chr1_25803629_+intronic
ADediting_1518665chr1_25803633_+intronic
ADediting_1518666chr1_25803653_+intronic
ADediting_1518667chr1_25803778_+intronic
ADediting_1518668chr1_25803791_+intronic
ADediting_1518669chr1_25803797_+intronic
ADediting_1518670chr1_25803798_+intronic
ADediting_1518671chr1_25803868_+intronic
ADediting_1518672chr1_25803912_+intronic
ADediting_1600237chr1_25801531_+intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_87998chr1_25801394_+SINEAluName=AluJb
ADediting_87999chr1_25801398_+SINEAluName=AluJb
ADediting_88000chr1_25801403_+SINEAluName=AluJb
ADediting_88001chr1_25801411_+SINEAluName=AluJb
ADediting_88002chr1_25801446_+SINEAluName=AluJb
ADediting_88003chr1_25801451_+SINEAluName=AluJb
ADediting_88004chr1_25801459_+SINEAluName=AluJb
ADediting_88005chr1_25801460_+SINEAluName=AluJb
ADediting_88006chr1_25801465_+SINEAluName=AluJb
ADediting_88007chr1_25801475_+SINEAluName=AluJb
ADediting_88008chr1_25801477_+SINEAluName=AluJb
ADediting_88009chr1_25801482_+SINEAluName=AluJb
ADediting_88010chr1_25801483_+SINEAluName=AluJb
ADediting_88011chr1_25801484_+SINEAluName=AluJb
ADediting_88012chr1_25801485_+SINEAluName=AluJb
ADediting_88013chr1_25801490_+SINEAluName=AluJb
ADediting_88014chr1_25801496_+SINEAluName=AluJb
ADediting_88015chr1_25801499_+SINEAluName=AluJb
ADediting_88016chr1_25801500_+SINEAluName=AluJb
ADediting_88017chr1_25801501_+SINEAluName=AluJb
ADediting_88018chr1_25801502_+SINEAluName=AluJb
ADediting_88019chr1_25801504_+SINEAluName=AluJb
ADediting_88020chr1_25801509_+SINEAluName=AluJb
ADediting_88021chr1_25801510_+SINEAluName=AluJb
ADediting_88022chr1_25801513_+SINEAluName=AluJb
ADediting_88023chr1_25801533_+SINEAluName=AluJb
ADediting_88024chr1_25801539_+SINEAluName=AluJb
ADediting_88025chr1_25801545_+SINEAluName=AluJb
ADediting_88026chr1_25801549_+SINEAluName=AluJb
ADediting_88027chr1_25801575_+SINEAluName=AluJb
ADediting_88028chr1_25801578_+SINEAluName=AluJb
ADediting_88029chr1_25801592_+SINEAluName=AluJb
ADediting_88030chr1_25801642_+SINEAluName=AluJb
ADediting_88031chr1_25801644_+SINEAluName=AluJb
ADediting_88032chr1_25801826_+SINEMIRName=MIR
ADediting_88033chr1_25802030_+SINEAluName=AluJb
ADediting_88034chr1_25802076_+SINEAluName=AluJb
ADediting_88035chr1_25802077_+SINEAluName=AluJb
ADediting_88036chr1_25802108_+SINEAluName=AluJb
ADediting_88037chr1_25802120_+SINEAluName=AluJb
ADediting_88038chr1_25802121_+SINEAluName=AluJb
ADediting_88039chr1_25802130_+SINEAluName=AluJb
ADediting_88040chr1_25802136_+SINEAluName=AluJb
ADediting_88041chr1_25802146_+SINEAluName=AluJb
ADediting_88042chr1_25802152_+SINEAluName=AluJb
ADediting_88043chr1_25802187_+SINEAluName=AluJb
ADediting_88044chr1_25802210_+SINEAluName=AluJb
ADediting_88045chr1_25802211_+SINEAluName=AluJb
ADediting_88046chr1_25802226_+SINEAluName=AluJb
ADediting_88047chr1_25802264_+SINEAluName=AluJb
ADediting_88048chr1_25802396_+SINEAluName=AluSx1
ADediting_88049chr1_25802460_+SINEAluName=AluSx1
ADediting_88050chr1_25802461_+SINEAluName=AluSx1
ADediting_88051chr1_25802474_+SINEAluName=AluSx1
ADediting_88052chr1_25802496_+SINEAluName=AluSx1
ADediting_88053chr1_25802561_+SINEAluName=AluSx1
ADediting_88054chr1_25803584_+SINEMIRName=MIRc
ADediting_88055chr1_25803585_+SINEMIRName=MIRc
ADediting_88056chr1_25803593_+SINEMIRName=MIRc
ADediting_88057chr1_25803597_+SINEMIRName=MIRc
ADediting_88058chr1_25803639_+SINEMIRName=MIRc
ADediting_88059chr1_25803651_+SINEMIRName=MIRc
ADediting_88060chr1_25803664_+SINEMIRName=MIRc
ADediting_88061chr1_25803729_+SINEAluName=AluSx
ADediting_88062chr1_25803801_+SINEAluName=AluSx
ADediting_88063chr1_25803802_+SINEAluName=AluSx
ADediting_88064chr1_25803842_+SINEAluName=AluSx
ADediting_88065chr1_25803864_+SINEAluName=AluSx
ADediting_88066chr1_25803886_+SINEAluName=AluSx
ADediting_88067chr1_25803888_+SINEAluName=AluSx
ADediting_88068chr1_25803913_+SINEAluName=AluSx
ADediting_88069chr1_25803923_+SINEAluName=AluSx
ADediting_88070chr1_25803924_+SINEAluName=AluSx
ADediting_88071chr1_25803931_+SINEAluName=AluSx
ADediting_88072chr1_25804880_+SINEMIRName=MIRb
ADediting_88073chr1_25804884_+SINEMIRName=MIRb
ADediting_88074chr1_25804898_+SINEMIRName=MIRb
ADediting_88075chr1_25804917_+SINEMIRName=MIRb
ADediting_1518643chr1_25801418_+SINEAluName=AluJb
ADediting_1518644chr1_25801508_+SINEAluName=AluJb
ADediting_1518645chr1_25801569_+SINEAluName=AluJb
ADediting_1518646chr1_25801588_+SINEAluName=AluJb
ADediting_1518647chr1_25801615_+SINEAluName=AluJb
ADediting_1518648chr1_25802010_+SINEAluName=AluJb
ADediting_1518649chr1_25802012_+SINEAluName=AluJb
ADediting_1518650chr1_25802132_+SINEAluName=AluJb
ADediting_1518651chr1_25802175_+SINEAluName=AluJb
ADediting_1518652chr1_25802225_+SINEAluName=AluJb
ADediting_1518653chr1_25802273_+SINEAluName=AluJb
ADediting_1518654chr1_25802426_+SINEAluName=AluSx1
ADediting_1518655chr1_25802483_+SINEAluName=AluSx1
ADediting_1518656chr1_25802486_+SINEAluName=AluSx1
ADediting_1518657chr1_25802502_+SINEAluName=AluSx1
ADediting_1518658chr1_25802530_+SINEAluName=AluSx1
ADediting_1518659chr1_25802536_+SINEAluName=AluSx1
ADediting_1518660chr1_25802539_+SINEAluName=AluSx1
ADediting_1518661chr1_25802577_+SINEAluName=AluSx1
ADediting_1518662chr1_25802578_+SINEAluName=AluSx1
ADediting_1518663chr1_25802618_+SINEAluName=AluSx1
ADediting_1518664chr1_25803629_+SINEMIRName=MIRc
ADediting_1518665chr1_25803633_+SINEMIRName=MIRc
ADediting_1518666chr1_25803653_+SINEMIRName=MIRc
ADediting_1518667chr1_25803778_+SINEAluName=AluSx
ADediting_1518668chr1_25803791_+SINEAluName=AluSx
ADediting_1518669chr1_25803797_+SINEAluName=AluSx
ADediting_1518670chr1_25803798_+SINEAluName=AluSx
ADediting_1518671chr1_25803868_+SINEAluName=AluSx
ADediting_1518672chr1_25803912_+SINEAluName=AluSx
ADediting_1600237chr1_25801531_+SINEAluName=AluJb

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RNA A-to-I editing events in the alternative splicing sites for SELENON

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
ESADediting_1518648chr1_25802010_+25801992:258020143ss2iACTTTTTTTTTTTTTTTGAGACA1.95ACTTTTTTTTTTTTTTTGGGACA-6.01
ESADediting_1518648chr1_25802010_+25801992:258020143ss2iACTTTTTTTTTTTTTTTGAGACA1.95ACTTTTTTTTTTTTTTTGGGACA-6.01
ESADediting_1518648chr1_25802010_+25801996:258020183ss6iTTTTTTTTTTTTTGAGACAGGGT4.19TTTTTTTTTTTTTGGGACAGGGT8.29
ESADediting_1518649chr1_25802012_+25801992:258020143ss1eACTTTTTTTTTTTTTTTGAGACA1.95ACTTTTTTTTTTTTTTTGAGGCA3.48
ESADediting_1518649chr1_25802012_+25801996:258020183ss4iTTTTTTTTTTTTTGAGACAGGGT4.19TTTTTTTTTTTTTGAGGCAGGGT3.74
ESADediting_88037chr1_25802120_+25802115:258021235ss3iTGAGTAAGT8.82TGAGTGAGT6.51
ESADediting_88037chr1_25802120_+25802115:258021235ss3iTGAGTAAGT8.82TGAGTGAGT6.51
ESADediting_88037chr1_25802120_+25802115:258021235ss3iTGAGTAAGT8.82TGAGTGAGT6.51
ESADediting_88038chr1_25802121_+25802115:258021235ss4iTGAGTAAGT8.82TGAGTAGGT3.27
ESADediting_88038chr1_25802121_+25802115:258021235ss4iTGAGTAAGT8.82TGAGTAGGT3.27
ESADediting_88038chr1_25802121_+25802115:258021235ss4iTGAGTAAGT8.82TGAGTAGGT3.27
ESADediting_88038chr1_25802121_+25802115:258021235ss4iTGAGTAAGT8.82TGAGTAGGT3.27
ME2ADediting_88033chr1_25802030_+25802016:258020383ss6iGGTCTTGTTCTGTCACCCAGACT4.87GGTCTTGTTCTGTCGCCCAGACT4.07
ME2ADediting_88033chr1_25802030_+25802016:258020383ss6iGGTCTTGTTCTGTCACCCAGACT4.87GGTCTTGTTCTGTCGCCCAGACT4.07
ME2ADediting_88037chr1_25802120_+25802115:258021235ss3iTGAGTAAGT8.82TGAGTGAGT6.51
ME2ADediting_88038chr1_25802121_+25802115:258021235ss4iTGAGTAAGT8.82TGAGTAGGT3.27

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SELENON

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

Soverview
Soverview
Soverview
Soverview
Soverview
ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for SELENON

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for SELENON


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337757chr7_5495852_-ENSG00000162430.17ENST00000354177.8SELENON-201hsa-miR-589-3pchr125817244258172507mer-m82581722725817251162-21.55
ADediting_1337757chr7_5495852_-ENSG00000162430.17ENST00000354177.8SELENON-201hsa-miR-589-3pchr125818005258180117mer-m82581798525818012144-18.02
ADediting_1337757chr7_5495852_-ENSG00000162430.17ENST00000361547.7SELENON-202hsa-miR-589-3pchr125817244258172507mer-m82581722725817251162-21.55
ADediting_1337757chr7_5495852_-ENSG00000162430.17ENST00000361547.7SELENON-202hsa-miR-589-3pchr125818005258180117mer-m82581798525818012144-18.02
ADediting_1337757chr7_5495852_-ENSG00000162430.17ENST00000374315.1SELENON-203hsa-miR-589-3pchr125817244258172507mer-m82581722725817251162-21.55
ADediting_1337757chr7_5495852_-ENSG00000162430.17ENST00000374315.1SELENON-203hsa-miR-589-3pchr125818005258180117mer-m82581798525818012144-18.02
ADediting_1337757chr7_5495852_-ENSG00000162430.17ENST00000630065.2SELENON-205hsa-miR-589-3pchr125817244258172507mer-m82581722725817251162-21.55
ADediting_1337757chr7_5495852_-ENSG00000162430.17ENST00000630065.2SELENON-205hsa-miR-589-3pchr125818005258180117mer-m82581798525818012144-18.02
ADediting_1337758chr7_5495892_-ENSG00000162430.17ENST00000354177.8SELENON-201hsa-miR-589-5pchr125816421258164277mer-m82581640725816428144-20.59
ADediting_1337758chr7_5495892_-ENSG00000162430.17ENST00000361547.7SELENON-202hsa-miR-589-5pchr125816421258164277mer-m82581640725816428144-20.59
ADediting_1337758chr7_5495892_-ENSG00000162430.17ENST00000374315.1SELENON-203hsa-miR-589-5pchr125816421258164277mer-m82581640725816428144-20.59
ADediting_1337758chr7_5495892_-ENSG00000162430.17ENST00000630065.2SELENON-205hsa-miR-589-5pchr125816421258164277mer-m82581640725816428144-20.59
ADediting_1535953chr14_101045971_+ENSG00000162430.17ENST00000354177.8SELENON-201hsa-miR-381-3pchr125816527258165337mer-m82581651325816534147-14.81
ADediting_1535953chr14_101045971_+ENSG00000162430.17ENST00000361547.7SELENON-202hsa-miR-381-3pchr125816527258165337mer-m82581651325816534147-14.81
ADediting_1535953chr14_101045971_+ENSG00000162430.17ENST00000374315.1SELENON-203hsa-miR-381-3pchr125816527258165337mer-m82581651325816534147-14.81
ADediting_1535953chr14_101045971_+ENSG00000162430.17ENST00000630065.2SELENON-205hsa-miR-381-3pchr125816527258165337mer-m82581651325816534147-14.81
ADediting_496066chr15_66496985_-ENSG00000162430.17ENST00000354177.8SELENON-201hsa-miR-4512chr125815743258157497mer-m82581573125815750151-21.75
ADediting_496066chr15_66496985_-ENSG00000162430.17ENST00000361547.7SELENON-202hsa-miR-4512chr125815743258157497mer-m82581573125815750151-21.75
ADediting_496066chr15_66496985_-ENSG00000162430.17ENST00000374315.1SELENON-203hsa-miR-4512chr125815743258157497mer-m82581573125815750151-21.75
ADediting_496066chr15_66496985_-ENSG00000162430.17ENST00000630065.2SELENON-205hsa-miR-4512chr125815743258157497mer-m82581573125815750151-21.75

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1391023chr8_140732605_-ENSG00000162430.17ENST00000354177.8SELENON-201hsa-miR-151a-3pchr125816037258160437mer-m82581602525816044144-16
ADediting_1391023chr8_140732605_-ENSG00000162430.17ENST00000361547.7SELENON-202hsa-miR-151a-3pchr125816037258160437mer-m82581602525816044144-16
ADediting_1391023chr8_140732605_-ENSG00000162430.17ENST00000374315.1SELENON-203hsa-miR-151a-3pchr125816037258160437mer-m82581602525816044144-16
ADediting_1391023chr8_140732605_-ENSG00000162430.17ENST00000630065.2SELENON-205hsa-miR-151a-3pchr125816037258160437mer-m82581602525816044144-16
ADediting_527135chr16_24203190_+ENSG00000162430.17ENST00000354177.8SELENON-201hsa-miR-1273h-3pchr125817705258177117mer-m82581769125817712145-14.37
ADediting_527135chr16_24203190_+ENSG00000162430.17ENST00000361547.7SELENON-202hsa-miR-1273h-3pchr125817705258177117mer-m82581769125817712145-14.37
ADediting_527135chr16_24203190_+ENSG00000162430.17ENST00000374315.1SELENON-203hsa-miR-1273h-3pchr125817705258177117mer-m82581769125817712145-14.37
ADediting_527135chr16_24203190_+ENSG00000162430.17ENST00000630065.2SELENON-205hsa-miR-1273h-3pchr125817705258177117mer-m82581769125817712145-14.37
ADediting_843620chr2_207754818_+ENSG00000162430.17ENST00000354177.8SELENON-201hsa-miR-4775chr125818203258182097mer-m82581819025818210150-7.04
ADediting_843620chr2_207754818_+ENSG00000162430.17ENST00000361547.7SELENON-202hsa-miR-4775chr125818203258182097mer-m82581819025818210150-7.04
ADediting_843620chr2_207754818_+ENSG00000162430.17ENST00000374315.1SELENON-203hsa-miR-4775chr125818203258182097mer-m82581819025818210150-7.04
ADediting_843620chr2_207754818_+ENSG00000162430.17ENST00000630065.2SELENON-205hsa-miR-4775chr125818203258182097mer-m82581819025818210150-7.04

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for SELENON

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000361547.7protein_codingSoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_88033ENST00000361547.7chr1_25802030_+354-1706.90-1706.90-1709.60
ADediting_88034ENST00000361547.7chr1_25802076_+400-1706.90-1706.90-1709.60
ADediting_88035ENST00000361547.7chr1_25802077_+401-1707.00-1706.90-1709.60
ADediting_88036ENST00000361547.7chr1_25802108_+432-1706.70-1706.90-1709.60

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for SELENON

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
CERADediting_1518644chr1_25801508_+0.008407216395699580.2144529693773822.84949902564666e-050.3346137027871090.04990054790653450.160403535264231
CERADediting_1518664chr1_25803629_+9.22741119943749e-080.4193516240692149.20576932636969e-070.3881501823550520.04610790444954860.163114647411282
CERADediting_87998chr1_25801394_+0.0001803850555256390.301167766594730.0926054085206470.1378161744688530.577803553364966-0.0458051826938709
DLPFCADediting_88024chr1_25801539_+0.08328111276208180.09852713252654180.554568218413965-0.03368905996007947.07249159818749e-130.392770889138405
DLPFCADediting_88027chr1_25801575_+0.009600282969924510.1468912958432940.8120934073603320.01355608768684911.50491008681927e-170.45887015473665
DLPFCADediting_88028chr1_25801578_+0.02069525274746550.1313586825902220.6649548396633070.02469343706817171.39536878836319e-080.315276968507208
CERADediting_88033chr1_25802030_+0.0005588697780118630.278493309295151.41517613494461e-060.3819457103579960.230937344670272-0.09839760993947
CERADediting_88037chr1_25802120_+0.002167252951246030.2485018357355431.26956120160023e-060.3835244615622510.2181649891842670.101133224382316
DLPFCADediting_88040chr1_25802136_+0.0005435767979295130.1953127984266690.06773298542653810.1038928489490483.22571320872956e-090.328183400157897
TCXADediting_88045chr1_25802211_+0.5901057545143860.04433249315778221.85357956959723e-050.3418769438762730.9515388004336320.00500404725282875
CERADediting_88046chr1_25802226_+0.003036105195016160.2404645526986161.90578119061952e-050.3414132816163510.005061397637286290.22776139145715
CERADediting_88053chr1_25802561_+0.0001729443104319350.3019772463048563.20459289797139e-050.3325980398382180.1303853232041410.124062182164922
CERADediting_88054chr1_25803584_+2.44523578859457e-060.3738660970535160.01107325736443340.2069023848781170.559342508062321-0.0480429342755409
CERADediting_88055chr1_25803585_+7.65268017692646e-050.3172001987490640.004860272308404630.228793678171130.7334180206389160.0280375105700315
CERADediting_88059chr1_25803651_+8.60453841248315e-070.3891132665345591.31257734742837e-060.3830408583312410.2985545147566390.0854373511870551
TCXADediting_88059chr1_25803651_+0.921087439769493-0.008156643104273870.0001073175937527660.3109864404499760.295486647500213-0.0859796655013174
CERADediting_88060chr1_25803664_+1.64039905560582e-060.3797850900944432.08001791976578e-060.3762786408689160.3948424477033650.0699732676746248
DLPFCADediting_88068chr1_25803913_+1.86701629810082e-060.2669151742470120.003237491282484170.166723171634042.6758872309579e-080.309336278401707
CERADediting_88073chr1_25804884_+0.0001780675000340120.3014165082841894.1245676383184e-050.3282182528593580.9720047233759510.0028895863381783

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC1.94907821899068e-150.4307611104408267.89018551905072e-090.3203737480996555.93816753493476e-310.594028748366318
AC1.22905971784799e-480.7616521066791653.82478240618132e-260.6030013874249851.61565999385574e-310.650926463327238
PCC3.7271162883418e-060.3275961201471540.0004308317354373530.2522540043673949.89833077654538e-060.313724200438042
TCX0.004435506221511850.2311059494568290.465284116674742-0.06006704672160941.56119319906574e-090.467943707959667
FP0.01371152614258470.1844511359623790.0517580807832153-0.146040702412241.21866258002822e-090.435655471133332
IFG0.001860931212895720.5911000857931440.002350297958348760.5804479120980760.00070501722809920.631797030268275
PG0.0316377889100037-0.1576453095898638.06143166426959e-05-0.2849863930950476.83083577491031e-070.354619619648087
STG0.2300390320033430.1323651239230690.110621584785828-0.1753488089233881.70061309270168e-070.533857161786512

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Relation with AD stages for SELENON

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
TCX3.81952881232054e-100.561477015470482

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RelatedDrugs for SELENON

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for SELENON

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource
SELENONC0410180Eichsfeld type congenital muscular dystrophy6CTD_human;ORPHANET;UNIPROT
SELENONC0270960Congenital myopathy (disorder)2GENOMICS_ENGLAND
SELENONC0003886Arthrogryposis1GENOMICS_ENGLAND
SELENONC0026850Muscular Dystrophy1CTD_human
SELENONC0546264Congenital Fiber Type Disproportion1CTD_human;ORPHANET;UNIPROT