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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for TIGAR

check button Gene summary
Gene informationGene symbol

TIGAR

Gene ID

57103

Gene nameTP53 induced glycolysis regulatory phosphatase
SynonymsC12orf5|FR2BP
Cytomap

12p13.32

Type of geneprotein-coding
Descriptionfructose-2,6-bisphosphatase TIGARTP53-induced glycolysis and apoptosis regulatorfructose-2,6-bisphosphate 2-phosphataseprobable fructose-2,6-bisphosphatase TIGARtransactivated by NS3TP2 protein
Modification date20200313
UniProtAcc

Q9NQ88,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
TIGAR

GO:0006003

fructose 2,6-bisphosphate metabolic process

19015259

TIGAR

GO:0006974

cellular response to DNA damage stimulus

25928429

TIGAR

GO:0030388

fructose 1,6-bisphosphate metabolic process

19015259

TIGAR

GO:0043069

negative regulation of programmed cell death

23185017

TIGAR

GO:0071279

cellular response to cobalt ion

25928429

TIGAR

GO:0071456

cellular response to hypoxia

23185017

TIGAR

GO:1903301

positive regulation of hexokinase activity

23185017


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RNA A-to-I events for TIGAR

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_344621(4312583, +), ADediting_344622(4312621, +), ADediting_344623(4312729, +), ADediting_344624(4312781, +), ADediting_344625(4313393, +), ADediting_344626(4313414, +), ADediting_344627(4316105, +), ADediting_344628(4316131, +), ADediting_344629(4316132, +), ADediting_344630(4316135, +), ADediting_344631(4322097, +), ADediting_344632(4322126, +), ADediting_344633(4322210, +), ADediting_344634(4322271, +), ADediting_344635(4323011, +), ADediting_344636(4323034, +), ADediting_344637(4323065, +), ADediting_344638(4323119, +), ADediting_344639(4323155, +), ADediting_344640(4323176, +), ADediting_344641(4323204, +), ADediting_344642(4323208, +), ADediting_344643(4323220, +), ADediting_344644(4323250, +), ADediting_344645(4323251, +), ADediting_344646(4325020, +), ADediting_344647(4325023, +), ADediting_344648(4325072, +), ADediting_344649(4325540, +), ADediting_344650(4325545, +), ADediting_344651(4325554, +), ADediting_344652(4325565, +), ADediting_344653(4325621, +), ADediting_344654(4325622, +), ADediting_344655(4325683, +), ADediting_344656(4327137, +), ADediting_344657(4327140, +), ADediting_344658(4327147, +), ADediting_344659(4327151, +), ADediting_344660(4327153, +), ADediting_344661(4327206, +), ADediting_344662(4327244, +), ADediting_344663(4327247, +), ADediting_344664(4327248, +), ADediting_344665(4327259, +), ADediting_344666(4327262, +), ADediting_344667(4327267, +), ADediting_344668(4327288, +), ADediting_344669(4327289, +), ADediting_344670(4327312, +), ADediting_344671(4327329, +), ADediting_344672(4327354, +), ADediting_344673(4327366, +), ADediting_344674(4327747, +), ADediting_344675(4327767, +), ADediting_344676(4327768, +), ADediting_344677(4327785, +), ADediting_344678(4327807, +), ADediting_344679(4327823, +), ADediting_344680(4327851, +), ADediting_344681(4327865, +), ADediting_344682(4327868, +), ADediting_344683(4327870, +), ADediting_344684(4327928, +), ADediting_344685(4327940, +), ADediting_344686(4327946, +), ADediting_344687(4328248, +), ADediting_344688(4328253, +), ADediting_344689(4328292, +), ADediting_344690(4328375, +), ADediting_344691(4337241, +), ADediting_344692(4337247, +), ADediting_344693(4337266, +), ADediting_344694(4337284, +), ADediting_344695(4337327, +), ADediting_344696(4337349, +), ADediting_344697(4337380, +), ADediting_344698(4337388, +), ADediting_344699(4337389, +), ADediting_344700(4337394, +), ADediting_344701(4337399, +), ADediting_344702(4337412, +), ADediting_344703(4337421, +), ADediting_344704(4337422, +), ADediting_344705(4337857, +), ADediting_344706(4337898, +), ADediting_344707(4337902, +), ADediting_344708(4337929, +), ADediting_344709(4337966, +), ADediting_344710(4337972, +), ADediting_344711(4337973, +), ADediting_344712(4337975, +), ADediting_344713(4337978, +), ADediting_344714(4337980, +), ADediting_344715(4337981, +), ADediting_344716(4337984, +), ADediting_344717(4337988, +), ADediting_344718(4338009, +), ADediting_344719(4338055, +), ADediting_344721(4347864, +), ADediting_344722(4347904, +), ADediting_344723(4347911, +), ADediting_344724(4347954, +), ADediting_344725(4347985, +), ADediting_344726(4348015, +), ADediting_344727(4348025, +), ADediting_344728(4348051, +), ADediting_344729(4349487, +), ADediting_344730(4349521, +), ADediting_344731(4349522, +), ADediting_344732(4349557, +), ADediting_344733(4349669, +), ADediting_344734(4350790, +), ADediting_344735(4353565, +), ADediting_344736(4353582, +), ADediting_344737(4353625, +), ADediting_344738(4353634, +), ADediting_344739(4353671, +), ADediting_344740(4353700, +), ADediting_344741(4353713, +), ADediting_344742(4353714, +), ADediting_344743(4353740, +), ADediting_344744(4353755, +), ADediting_344745(4353809, +), ADediting_344746(4354788, +), ADediting_344747(4354796, +), ADediting_344748(4354806, +), ADediting_344749(4354812, +), ADediting_344750(4354831, +), ADediting_344751(4354832, +), ADediting_344752(4354835, +), ADediting_344753(4354849, +), ADediting_344754(4354861, +), ADediting_344755(4354871, +), ADediting_344756(4354914, +), ADediting_344757(4354940, +), ADediting_344758(4354974, +), ADediting_344759(4354992, +), ADediting_344760(4354993, +), ADediting_344761(4355011, +), ADediting_344762(4355014, +), ADediting_344763(4357871, +), ADediting_344764(4357879, +), ADediting_344765(4357920, +), ADediting_344766(4357983, +), ADediting_344767(4358054, +), ADediting_344768(4358188, +), ADediting_344769(4358211, +), ADediting_344770(4358220, +), ADediting_344771(4358235, +), ADediting_1613734(4334384, +), ADediting_1613735(4334404, +),

Top

RNA editing positional annotations for TIGAR using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_344621chr12_4312583_+intronic
ADediting_344622chr12_4312621_+intronic
ADediting_344623chr12_4312729_+intronic
ADediting_344624chr12_4312781_+intronic
ADediting_344625chr12_4313393_+intronic
ADediting_344626chr12_4313414_+intronic
ADediting_344627chr12_4316105_+intronic
ADediting_344628chr12_4316131_+intronic
ADediting_344629chr12_4316132_+intronic
ADediting_344630chr12_4316135_+intronic
ADediting_344631chr12_4322097_+intronic
ADediting_344632chr12_4322126_+intronic
ADediting_344633chr12_4322210_+intronic
ADediting_344634chr12_4322271_+intronic
ADediting_344635chr12_4323011_+intronic
ADediting_344636chr12_4323034_+intronic
ADediting_344637chr12_4323065_+intronic
ADediting_344638chr12_4323119_+intronic
ADediting_344639chr12_4323155_+intronic
ADediting_344640chr12_4323176_+intronic
ADediting_344641chr12_4323204_+intronic
ADediting_344642chr12_4323208_+intronic
ADediting_344643chr12_4323220_+intronic
ADediting_344644chr12_4323250_+intronic
ADediting_344645chr12_4323251_+intronic
ADediting_344646chr12_4325020_+intronic
ADediting_344647chr12_4325023_+intronic
ADediting_344648chr12_4325072_+intronic
ADediting_344649chr12_4325540_+intronic
ADediting_344650chr12_4325545_+intronic
ADediting_344651chr12_4325554_+intronic
ADediting_344652chr12_4325565_+intronic
ADediting_344653chr12_4325621_+intronic
ADediting_344654chr12_4325622_+intronic
ADediting_344655chr12_4325683_+intronic
ADediting_344656chr12_4327137_+intronic
ADediting_344657chr12_4327140_+intronic
ADediting_344658chr12_4327147_+intronic
ADediting_344659chr12_4327151_+intronic
ADediting_344660chr12_4327153_+intronic
ADediting_344661chr12_4327206_+intronic
ADediting_344662chr12_4327244_+intronic
ADediting_344663chr12_4327247_+intronic
ADediting_344664chr12_4327248_+intronic
ADediting_344665chr12_4327259_+intronic
ADediting_344666chr12_4327262_+intronic
ADediting_344667chr12_4327267_+intronic
ADediting_344668chr12_4327288_+intronic
ADediting_344669chr12_4327289_+intronic
ADediting_344670chr12_4327312_+intronic
ADediting_344671chr12_4327329_+intronic
ADediting_344672chr12_4327354_+intronic
ADediting_344673chr12_4327366_+intronic
ADediting_344674chr12_4327747_+intronic
ADediting_344675chr12_4327767_+intronic
ADediting_344676chr12_4327768_+intronic
ADediting_344677chr12_4327785_+intronic
ADediting_344678chr12_4327807_+intronic
ADediting_344679chr12_4327823_+intronic
ADediting_344680chr12_4327851_+intronic
ADediting_344681chr12_4327865_+intronic
ADediting_344682chr12_4327868_+intronic
ADediting_344683chr12_4327870_+intronic
ADediting_344684chr12_4327928_+intronic
ADediting_344685chr12_4327940_+intronic
ADediting_344686chr12_4327946_+intronic
ADediting_344687chr12_4328248_+intronic
ADediting_344688chr12_4328253_+intronic
ADediting_344689chr12_4328292_+intronic
ADediting_344690chr12_4328375_+intronic
ADediting_344691chr12_4337241_+intronic
ADediting_344692chr12_4337247_+intronic
ADediting_344693chr12_4337266_+intronic
ADediting_344694chr12_4337284_+intronic
ADediting_344695chr12_4337327_+intronic
ADediting_344696chr12_4337349_+intronic
ADediting_344697chr12_4337380_+intronic
ADediting_344698chr12_4337388_+intronic
ADediting_344699chr12_4337389_+intronic
ADediting_344700chr12_4337394_+intronic
ADediting_344701chr12_4337399_+intronic
ADediting_344702chr12_4337412_+intronic
ADediting_344703chr12_4337421_+intronic
ADediting_344704chr12_4337422_+intronic
ADediting_344705chr12_4337857_+intronic
ADediting_344706chr12_4337898_+intronic
ADediting_344707chr12_4337902_+intronic
ADediting_344708chr12_4337929_+intronic
ADediting_344709chr12_4337966_+intronic
ADediting_344710chr12_4337972_+intronic
ADediting_344711chr12_4337973_+intronic
ADediting_344712chr12_4337975_+intronic
ADediting_344713chr12_4337978_+intronic
ADediting_344714chr12_4337980_+intronic
ADediting_344715chr12_4337981_+intronic
ADediting_344716chr12_4337984_+intronic
ADediting_344717chr12_4337988_+intronic
ADediting_344718chr12_4338009_+intronic
ADediting_344719chr12_4338055_+intronic
ADediting_344721chr12_4347864_+intronic
ADediting_344722chr12_4347904_+intronic
ADediting_344723chr12_4347911_+intronic
ADediting_344724chr12_4347954_+intronic
ADediting_344725chr12_4347985_+intronic
ADediting_344726chr12_4348015_+intronic
ADediting_344727chr12_4348025_+intronic
ADediting_344728chr12_4348051_+intronic
ADediting_344729chr12_4349487_+intronic
ADediting_344730chr12_4349521_+intronic
ADediting_344731chr12_4349522_+intronic
ADediting_344732chr12_4349557_+intronic
ADediting_344733chr12_4349669_+intronic
ADediting_344734chr12_4350790_+intronic
ADediting_344735chr12_4353565_+UTR3
ADediting_344736chr12_4353582_+UTR3
ADediting_344737chr12_4353625_+UTR3
ADediting_344738chr12_4353634_+UTR3
ADediting_344739chr12_4353671_+UTR3
ADediting_344740chr12_4353700_+UTR3
ADediting_344741chr12_4353713_+UTR3
ADediting_344742chr12_4353714_+UTR3
ADediting_344743chr12_4353740_+UTR3
ADediting_344744chr12_4353755_+UTR3
ADediting_344745chr12_4353809_+UTR3
ADediting_344746chr12_4354788_+UTR3
ADediting_344747chr12_4354796_+UTR3
ADediting_344748chr12_4354806_+UTR3
ADediting_344749chr12_4354812_+UTR3
ADediting_344750chr12_4354831_+UTR3
ADediting_344751chr12_4354832_+UTR3
ADediting_344752chr12_4354835_+UTR3
ADediting_344753chr12_4354849_+UTR3
ADediting_344754chr12_4354861_+UTR3
ADediting_344755chr12_4354871_+UTR3
ADediting_344756chr12_4354914_+UTR3
ADediting_344757chr12_4354940_+UTR3
ADediting_344758chr12_4354974_+UTR3
ADediting_344759chr12_4354992_+UTR3
ADediting_344760chr12_4354993_+UTR3
ADediting_344761chr12_4355011_+UTR3
ADediting_344762chr12_4355014_+UTR3
ADediting_344763chr12_4357871_+UTR3
ADediting_344764chr12_4357879_+UTR3
ADediting_344765chr12_4357920_+UTR3
ADediting_344766chr12_4357983_+UTR3
ADediting_344767chr12_4358054_+UTR3
ADediting_344768chr12_4358188_+UTR3
ADediting_344769chr12_4358211_+UTR3
ADediting_344770chr12_4358220_+UTR3
ADediting_344771chr12_4358235_+UTR3
ADediting_1613734chr12_4334384_+intronic
ADediting_1613735chr12_4334404_+intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_344621chr12_4312583_+SINEAluName=AluSz
ADediting_344622chr12_4312621_+SINEAluName=AluSz
ADediting_344623chr12_4312729_+SINEAluName=AluSz
ADediting_344624chr12_4312781_+SINEAluName=AluSz
ADediting_344625chr12_4313393_+SINEAluName=AluSx
ADediting_344626chr12_4313414_+SINEAluName=AluSx
ADediting_344627chr12_4316105_+SINEAluName=AluSq
ADediting_344628chr12_4316131_+SINEAluName=AluSq
ADediting_344629chr12_4316132_+SINEAluName=AluSq
ADediting_344630chr12_4316135_+SINEAluName=AluSq
ADediting_344631chr12_4322097_+SINEAluName=AluSz
ADediting_344632chr12_4322126_+SINEAluName=AluSz
ADediting_344633chr12_4322210_+SINEAluName=AluSz
ADediting_344634chr12_4322271_+SINEAluName=AluSz
ADediting_344635chr12_4323011_+SINEAluName=AluJb
ADediting_344636chr12_4323034_+SINEAluName=AluJb
ADediting_344637chr12_4323065_+SINEAluName=AluJb
ADediting_344638chr12_4323119_+SINEAluName=AluJb
ADediting_344639chr12_4323155_+SINEAluName=AluJb
ADediting_344640chr12_4323176_+SINEAluName=AluJb
ADediting_344641chr12_4323204_+SINEAluName=AluJb
ADediting_344642chr12_4323208_+SINEAluName=AluJb
ADediting_344643chr12_4323220_+SINEAluName=AluJb
ADediting_344644chr12_4323250_+SINEAluName=AluJb
ADediting_344645chr12_4323251_+SINEAluName=AluJb
ADediting_344646chr12_4325020_+SINEAluName=AluSp
ADediting_344647chr12_4325023_+SINEAluName=AluSp
ADediting_344648chr12_4325072_+SINEAluName=AluSp
ADediting_344649chr12_4325540_+SINEAluName=AluSq2
ADediting_344650chr12_4325545_+SINEAluName=AluSq2
ADediting_344651chr12_4325554_+SINEAluName=AluSq2
ADediting_344652chr12_4325565_+SINEAluName=AluSq2
ADediting_344653chr12_4325621_+SINEAluName=AluSq2
ADediting_344654chr12_4325622_+SINEAluName=AluSq2
ADediting_344655chr12_4325683_+SINEAluName=AluSq2
ADediting_344656chr12_4327137_+SINEAluName=AluSx
ADediting_344657chr12_4327140_+SINEAluName=AluSx
ADediting_344658chr12_4327147_+SINEAluName=AluSx
ADediting_344659chr12_4327151_+SINEAluName=AluSx
ADediting_344660chr12_4327153_+SINEAluName=AluSx
ADediting_344661chr12_4327206_+SINEAluName=AluSx
ADediting_344662chr12_4327244_+SINEAluName=AluSx
ADediting_344663chr12_4327247_+SINEAluName=AluSx
ADediting_344664chr12_4327248_+SINEAluName=AluSx
ADediting_344665chr12_4327259_+SINEAluName=AluSx
ADediting_344666chr12_4327262_+SINEAluName=AluSx
ADediting_344667chr12_4327267_+SINEAluName=AluSx
ADediting_344668chr12_4327288_+SINEAluName=AluSx
ADediting_344669chr12_4327289_+SINEAluName=AluSx
ADediting_344670chr12_4327312_+SINEAluName=AluSx
ADediting_344671chr12_4327329_+SINEAluName=AluSx
ADediting_344672chr12_4327354_+SINEAluName=AluSx
ADediting_344673chr12_4327366_+SINEAluName=AluSx
ADediting_344674chr12_4327747_+SINEAluName=AluSx4
ADediting_344675chr12_4327767_+SINEAluName=AluSx4
ADediting_344676chr12_4327768_+SINEAluName=AluSx4
ADediting_344677chr12_4327785_+SINEAluName=AluSx4
ADediting_344678chr12_4327807_+SINEAluName=AluSx4
ADediting_344679chr12_4327823_+SINEAluName=AluSx4
ADediting_344680chr12_4327851_+SINEAluName=AluSx4
ADediting_344681chr12_4327865_+SINEAluName=AluSx4
ADediting_344682chr12_4327868_+SINEAluName=AluSx4
ADediting_344683chr12_4327870_+SINEAluName=AluSx4
ADediting_344684chr12_4327928_+SINEAluName=AluSx4
ADediting_344685chr12_4327940_+SINEAluName=AluSx4
ADediting_344686chr12_4327946_+SINEAluName=AluSx4
ADediting_344687chr12_4328248_+SINEAluName=AluSq2
ADediting_344688chr12_4328253_+SINEAluName=AluSq2
ADediting_344689chr12_4328292_+SINEAluName=AluSq2
ADediting_344690chr12_4328375_+SINEAluName=AluSq2
ADediting_344691chr12_4337241_+SINEAluName=AluSz6
ADediting_344692chr12_4337247_+SINEAluName=AluSz6
ADediting_344693chr12_4337266_+SINEAluName=AluSz6
ADediting_344694chr12_4337284_+SINEAluName=AluSz6
ADediting_344695chr12_4337327_+SINEAluName=AluSz6
ADediting_344696chr12_4337349_+SINEAluName=AluSz6
ADediting_344697chr12_4337380_+SINEAluName=AluSz6
ADediting_344698chr12_4337388_+SINEAluName=AluSz6
ADediting_344699chr12_4337389_+SINEAluName=AluSz6
ADediting_344700chr12_4337394_+SINEAluName=AluSz6
ADediting_344701chr12_4337399_+SINEAluName=AluSz6
ADediting_344702chr12_4337412_+SINEAluName=AluSz6
ADediting_344703chr12_4337421_+SINEAluName=AluSz6
ADediting_344704chr12_4337422_+SINEAluName=AluSz6
ADediting_344705chr12_4337857_+SINEAluName=AluSz
ADediting_344706chr12_4337898_+SINEAluName=AluSz
ADediting_344707chr12_4337902_+SINEAluName=AluSz
ADediting_344708chr12_4337929_+SINEAluName=AluSz
ADediting_344709chr12_4337966_+SINEAluName=AluSz
ADediting_344710chr12_4337972_+SINEAluName=AluSz
ADediting_344711chr12_4337973_+SINEAluName=AluSz
ADediting_344712chr12_4337975_+SINEAluName=AluSz
ADediting_344713chr12_4337978_+SINEAluName=AluSz
ADediting_344714chr12_4337980_+SINEAluName=AluSz
ADediting_344715chr12_4337981_+SINEAluName=AluSz
ADediting_344716chr12_4337984_+SINEAluName=AluSz
ADediting_344717chr12_4337988_+SINEAluName=AluSz
ADediting_344718chr12_4338009_+SINEAluName=AluSz
ADediting_344719chr12_4338055_+SINEAluName=AluSz
ADediting_344721chr12_4347864_+SINEAluName=AluJb
ADediting_344722chr12_4347904_+SINEAluName=AluJb
ADediting_344723chr12_4347911_+SINEAluName=AluJb
ADediting_344724chr12_4347954_+SINEAluName=AluJb
ADediting_344725chr12_4347985_+SINEAluName=AluJb
ADediting_344726chr12_4348015_+SINEAluName=AluJb
ADediting_344727chr12_4348025_+SINEAluName=AluJb
ADediting_344728chr12_4348051_+SINEAluName=AluJb
ADediting_344729chr12_4349487_+SINEAluName=AluSc8
ADediting_344730chr12_4349521_+SINEAluName=AluSc8
ADediting_344731chr12_4349522_+SINEAluName=AluSc8
ADediting_344732chr12_4349557_+SINEAluName=AluSc8
ADediting_344733chr12_4349669_+SINEAluName=AluSc8
ADediting_344734chr12_4350790_+SINEAluName=AluSc8
ADediting_344735chr12_4353565_+SINEAluName=AluSg
ADediting_344736chr12_4353582_+SINEAluName=AluSg
ADediting_344737chr12_4353625_+SINEAluName=AluSg
ADediting_344738chr12_4353634_+SINEAluName=AluSg
ADediting_344739chr12_4353671_+SINEAluName=AluSg
ADediting_344740chr12_4353700_+SINEAluName=AluSg
ADediting_344741chr12_4353713_+SINEAluName=AluSg
ADediting_344742chr12_4353714_+SINEAluName=AluSg
ADediting_344743chr12_4353740_+SINEAluName=AluSg
ADediting_344744chr12_4353755_+SINEAluName=AluSg
ADediting_344745chr12_4353809_+SINEAluName=AluSg
ADediting_344746chr12_4354788_+SINEAluName=AluSz6
ADediting_344747chr12_4354796_+SINEAluName=AluSz6
ADediting_344748chr12_4354806_+SINEAluName=AluSz6
ADediting_344749chr12_4354812_+SINEAluName=AluSz6
ADediting_344750chr12_4354831_+SINEAluName=AluSz6
ADediting_344751chr12_4354832_+SINEAluName=AluSz6
ADediting_344752chr12_4354835_+SINEAluName=AluSz6
ADediting_344753chr12_4354849_+SINEAluName=AluSz6
ADediting_344754chr12_4354861_+SINEAluName=AluSz6
ADediting_344755chr12_4354871_+SINEAluName=AluSz6
ADediting_344756chr12_4354914_+SINEAluName=AluSz6
ADediting_344757chr12_4354940_+SINEAluName=AluSz6
ADediting_344758chr12_4354974_+SINEAluName=AluSz6
ADediting_344759chr12_4354992_+SINEAluName=AluSz6
ADediting_344760chr12_4354993_+SINEAluName=AluSz6
ADediting_344761chr12_4355011_+SINEAluName=AluSz6
ADediting_344762chr12_4355014_+SINEAluName=AluSz6
ADediting_344763chr12_4357871_+SINEAluName=AluY
ADediting_344764chr12_4357879_+SINEAluName=AluY
ADediting_344765chr12_4357920_+SINEAluName=AluY
ADediting_344766chr12_4357983_+SINEAluName=AluY
ADediting_344767chr12_4358054_+SINEAluName=AluY
ADediting_344768chr12_4358188_+SINEAluName=AluSx
ADediting_344769chr12_4358211_+SINEAluName=AluSx
ADediting_344770chr12_4358220_+SINEAluName=AluSx
ADediting_344771chr12_4358235_+SINEAluName=AluSx
ADediting_1613734chr12_4334384_+LTRERVL-MaLRName=MLT1A0
ADediting_1613735chr12_4334404_+LTRERVL-MaLRName=MLT1A0

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RNA A-to-I editing events in the alternative splicing sites for TIGAR

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for TIGAR

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for TIGAR

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for TIGAR

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_344735chr12_4353565_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-181d-3pchr12435356143535677mer-m843535484353568140-22.36
ADediting_344735chr12_4353565_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-181d-3pchr12435356143535677mer-m843535484353568140-22.36
ADediting_344738chr12_4353634_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-198chr12435363043536367mer-m843536164353637141-18.93
ADediting_344738chr12_4353634_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-198chr12435363043536367mer-m843536164353637141-18.93
ADediting_344740chr12_4353700_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-4715-3pchr12435369643537027mer-m843536814353703147-17.52
ADediting_344740chr12_4353700_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-4722-3pchr12435369843537047mer-m843536864353705156-25.34
ADediting_344740chr12_4353700_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-6727-3pchr12435369843537047mer-m843536864353705157-23.87
ADediting_344740chr12_4353700_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-4715-3pchr12435369643537027mer-m843536814353703147-17.52
ADediting_344740chr12_4353700_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-4722-3pchr12435369843537047mer-m843536864353705156-25.34
ADediting_344740chr12_4353700_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-6727-3pchr12435369843537047mer-m843536864353705157-23.87
ADediting_344741chr12_4353713_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-513a-5pchr12435370743537137mer-m843536974353714140-14.36
ADediting_344741chr12_4353713_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-638chr12435371243537187mer-1a43536944353718154-32.42
ADediting_344741chr12_4353713_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-513a-5pchr12435370743537137mer-m843536974353714140-14.36
ADediting_344741chr12_4353713_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-638chr12435371243537187mer-1a43536944353718154-32.42
ADediting_344742chr12_4353714_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-8052chr12435371243537187mer-1a43536984353718145-22.32
ADediting_344742chr12_4353714_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-8052chr12435371243537187mer-1a43536984353718145-22.32
ADediting_344744chr12_4353755_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-4437chr12435375143537577mer-m843537384353758146-19.53
ADediting_344744chr12_4353755_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-4437chr12435375143537577mer-m843537384353758146-19.53
ADediting_344745chr12_4353809_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-500b-3pchr12435380643538138mer-1a43537954353813155-22.56
ADediting_344745chr12_4353809_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-500b-3pchr12435380643538138mer-1a43537954353813155-22.56
ADediting_344746chr12_4354788_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-324-3pchr12435478443547907mer-m843547694354791156-26.93
ADediting_344746chr12_4354788_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-4252chr12435478543547917mer-m843547724354792146-20.82
ADediting_344749chr12_4354812_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-17-3pchr12435480543548117mer-m843547924354812153-18.02
ADediting_344749chr12_4354812_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-485-5pchr12435480943548157mer-m843547964354816153-17.86
ADediting_344749chr12_4354812_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-6884-5pchr12435480943548157mer-m843547944354816146-20.16
ADediting_344753chr12_4354849_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-6089chr12435484743548537mer-m843548314354854153-31.53
ADediting_344754chr12_4354861_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-4691-3pchr12435485843548647mer-m843548394354865153-28.71
ADediting_344755chr12_4354871_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-17-3pchr12435486743548737mer-m843548524354874150-22.27
ADediting_344757chr12_4354940_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-3940-3pchr12435493743549437mer-m843549264354944144-24.53
ADediting_344758chr12_4354974_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-3937chr12435497143549777mer-m843549594354978144-23.68
ADediting_344759chr12_4354992_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-1299chr12435498643549927mer-m843549724354993152-17.3
ADediting_344759chr12_4354992_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-514a-5pchr12435498843549947mer-m843549754354995154-17.61
ADediting_344759chr12_4354992_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-518c-5pchr12435498743549937mer-m843549694354994154-21.04
ADediting_344760chr12_4354993_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-6813-3pchr12435498843549947mer-m843549754354995140-12.94
ADediting_344763chr12_4357871_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-3176chr12435786443578707mer-m843578534357871140-15.24
ADediting_344763chr12_4357871_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-3922-3pchr12435786443578707mer-m843578504357871141-19.73
ADediting_344766chr12_4357983_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-140-3pchr12435797843579847mer-m843579654357985152-22.25
ADediting_344767chr12_4358054_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-149-5pchr12435804743580537mer-m843580294358054155-28.43
ADediting_344767chr12_4358054_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-4725-5pchr12435805143580577mer-m843580384358058143-14.17
ADediting_344767chr12_4358054_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-504-5pchr12435805143580577mer-m843580324358058162-31.5
ADediting_344768chr12_4358188_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-3176chr12435818143581877mer-m843581704358188140-15.24
ADediting_344768chr12_4358188_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-3620-3pchr12435818543581917mer-m843581704358192156-24.24
ADediting_344768chr12_4358188_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-3922-3pchr12435818143581877mer-m843581674358188141-19.73
ADediting_344770chr12_4358220_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-12113chr12435821343582197mer-m843582004358220147-19.86
ADediting_344770chr12_4358220_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-4539chr12435821343582197mer-m843582014358220151-20
ADediting_344771chr12_4358235_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-3190-5pchr12435822843582347mer-m843582164358235152-19.64

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_344735chr12_4353565_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-4252chr12435356343535697mer-m843535524353570150-23.24
ADediting_344735chr12_4353565_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-6724-5pchr12435355843535647mer-m843535424353565150-30.21
ADediting_344735chr12_4353565_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-6773-5pchr12435355843535647mer-m843535434353565144-24.47
ADediting_344735chr12_4353565_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-4252chr12435356343535697mer-m843535524353570150-23.24
ADediting_344735chr12_4353565_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-6724-5pchr12435355843535647mer-m843535424353565150-30.21
ADediting_344735chr12_4353565_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-6773-5pchr12435355843535647mer-m843535434353565144-24.47
ADediting_344736chr12_4353582_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-10399-5pchr12435357643535827mer-m843535624353583148-10
ADediting_344736chr12_4353582_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-5089-5pchr12435358043535867mer-m843535654353587148-13.62
ADediting_344736chr12_4353582_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-6504-3pchr12435357643535827mer-m843535624353583149-15.11
ADediting_344736chr12_4353582_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-10399-5pchr12435357643535827mer-m843535624353583148-10
ADediting_344736chr12_4353582_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-5089-5pchr12435358043535867mer-m843535654353587148-13.62
ADediting_344736chr12_4353582_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-6504-3pchr12435357643535827mer-m843535624353583149-15.11
ADediting_344737chr12_4353625_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-378a-5pchr12435362143536288mer-1a43536064353628148-19.28
ADediting_344737chr12_4353625_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-378a-5pchr12435362143536288mer-1a43536064353628148-19.28
ADediting_344739chr12_4353671_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-6832-5pchr12435366543536717mer-m843536504353672140-18.87
ADediting_344739chr12_4353671_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-6832-5pchr12435366543536717mer-m843536504353672140-18.87
ADediting_344741chr12_4353713_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-10399-5pchr12435370843537147mer-m843536964353715145-11.92
ADediting_344741chr12_4353713_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-6504-3pchr12435370843537147mer-m843536964353715140-11.31
ADediting_344741chr12_4353713_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-7151-3pchr12435370643537138mer-1a43536934353713140-12.37
ADediting_344741chr12_4353713_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-10399-5pchr12435370843537147mer-m843536964353715145-11.92
ADediting_344741chr12_4353713_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-6504-3pchr12435370843537147mer-m843536964353715140-11.31
ADediting_344741chr12_4353713_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-7151-3pchr12435370643537138mer-1a43536934353713140-12.37
ADediting_344742chr12_4353714_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-10399-5pchr12435370843537147mer-m843536964353715145-11.92
ADediting_344742chr12_4353714_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-5089-5pchr12435371243537187mer-m843536994353719144-13.5
ADediting_344742chr12_4353714_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-6504-3pchr12435370843537147mer-m843536964353715140-11.31
ADediting_344742chr12_4353714_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-10399-5pchr12435370843537147mer-m843536964353715145-11.92
ADediting_344742chr12_4353714_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-5089-5pchr12435371243537187mer-m843536994353719144-13.5
ADediting_344742chr12_4353714_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-6504-3pchr12435370843537147mer-m843536964353715140-11.31
ADediting_344743chr12_4353740_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-1976chr12435373743537448mer-1a43537244353744149-21.88
ADediting_344743chr12_4353740_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-6747-3pchr12435373543537428mer-1a43537214353742150-24.42
ADediting_344743chr12_4353740_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-1976chr12435373743537448mer-1a43537244353744149-21.88
ADediting_344743chr12_4353740_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-6747-3pchr12435373543537428mer-1a43537214353742150-24.42
ADediting_344744chr12_4353755_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-498-5pchr12435374843537547mer-m843537334353755142-9.71
ADediting_344744chr12_4353755_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-498-5pchr12435374843537547mer-m843537334353755142-9.71
ADediting_344745chr12_4353809_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-645chr12435380343538097mer-m843537934353810153-20.7
ADediting_344745chr12_4353809_+ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-645chr12435380343538097mer-m843537934353810153-20.7
ADediting_344746chr12_4354788_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-25-3pchr12435478243547887mer-m843547664354789153-25.3
ADediting_344746chr12_4354788_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-32-5pchr12435478243547887mer-m843547684354789144-14.72
ADediting_344746chr12_4354788_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-363-3pchr12435478243547887mer-m843547684354789147-16.16
ADediting_344746chr12_4354788_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-92a-3pchr12435478243547887mer-m843547724354789155-28.32
ADediting_344746chr12_4354788_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-92b-3pchr12435478243547887mer-m843547724354789155-25.05
ADediting_344748chr12_4354806_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-6807-5pchr12435479943548057mer-m843547854354806144-19.38
ADediting_344749chr12_4354812_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-377-5pchr12435480943548157mer-m843547954354816155-17.55
ADediting_344749chr12_4354812_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-6086chr12435480943548157mer-m843547974354816148-21.93
ADediting_344749chr12_4354812_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-6516-5pchr12435480543548117mer-m843547894354812145-14.71
ADediting_344752chr12_4354835_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-219b-3pchr12435483243548387mer-m843548194354839153-15.53
ADediting_344752chr12_4354835_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-302fchr12435483143548377mer-m843548224354838145-8.14
ADediting_344753chr12_4354849_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-3929chr12435484643548527mer-m843548324354853148-17.12
ADediting_344753chr12_4354849_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-4478chr12435484643548527mer-m843548364354853146-20.98
ADediting_344753chr12_4354849_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-4649-3pchr12435484343548497mer-m843548304354850140-12.74
ADediting_344753chr12_4354849_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-6884-5pchr12435484743548537mer-m843548334354854150-19.28
ADediting_344753chr12_4354849_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-7160-5pchr12435484443548507mer-m843548314354851151-21.55
ADediting_344754chr12_4354861_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-5690chr12435485843548647mer-m843548454354865145-17.72
ADediting_344755chr12_4354871_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-20b-3pchr12435486743548737mer-m843548524354874153-18.04
ADediting_344756chr12_4354914_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-4684-5pchr12435491143549177mer-m843548974354918152-12.03
ADediting_344757chr12_4354940_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-3190-5pchr12435493443549407mer-m843549224354941146-20.24
ADediting_344757chr12_4354940_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-548schr12435493343549397mer-m843549184354940146-14.51
ADediting_344758chr12_4354974_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-12114chr12435497043549767mer-m843549584354977152-28.83
ADediting_344758chr12_4354974_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-3165chr12435496943549757mer-m843549574354976145-17.91
ADediting_344758chr12_4354974_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-3665chr12435497243549787mer-m843549624354979140-17.7
ADediting_344761chr12_4355011_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-4633-5pchr12435500643550138mer-1a43549954355013151-16.16
ADediting_344761chr12_4355011_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-6894-3pchr12435500443550107mer-m843549914355011146-19
ADediting_344765chr12_4357920_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-892achr12435791543579217mer-m843579024357922140-15.2
ADediting_344766chr12_4357983_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-7151-3pchr12435797643579827mer-m843579594357983145-24.14
ADediting_344767chr12_4358054_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-6813-3pchr12435805043580567mer-m843580364358057148-15.17
ADediting_344771chr12_4358235_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-4716-5pchr12435823343582397mer-m843582194358240140-11.3
ADediting_344771chr12_4358235_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-4781-3pchr12435823143582377mer-m843582204358238144-13.86

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337757chr7_5495852_-ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-589-3pchr12435354743535537mer-m843535314353554140-16.37
ADediting_1337757chr7_5495852_-ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-589-3pchr12435383343538397mer-m843538164353840148-21.67
ADediting_1337757chr7_5495852_-ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-589-3pchr12435387943538868mer-1a43538624353886156-24.59
ADediting_1337757chr7_5495852_-ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-589-3pchr12435586943558757mer-m843558564355876142-15.09
ADediting_1337757chr7_5495852_-ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-589-3pchr12435354743535537mer-m843535314353554140-16.37
ADediting_1337757chr7_5495852_-ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-589-3pchr12435383343538397mer-m843538164353840148-21.67
ADediting_1337757chr7_5495852_-ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-589-3pchr12435387943538868mer-1a43538624353886156-24.59
ADediting_1535953chr14_101045971_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-381-3pchr12435720843572147mer-m843571944357215140-12.36
ADediting_1631458chr19_40282624_-ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-641chr12435880343588097mer-m843587854358810156-15.77
ADediting_286380chr11_79422188_-ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-5579-3pchr12435501143550177mer-m843549934355018149-16.15
ADediting_843620chr2_207754818_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-4775chr12435811743581237mer-m843581034358124162-6.65
ADediting_843620chr2_207754818_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-4775chr12435831043583167mer-m843582964358317158-7.61
ADediting_98289chr1_32086992_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-5585-3pchr12435690043569067mer-m843568774356907141-21.88

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_107020chr1_37500952_-ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-5581-3pchr12435588843558958mer-1a43558724355895152-23.77
ADediting_1097295chr3_85385762_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-5688chr12435958643595927mer-m843595724359593147-9.4
ADediting_1337757chr7_5495852_-ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-589-3pchr12435932943593357mer-m843593114359336152-20.23
ADediting_1535951chr14_100874558_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-337-3pchr12435613143561377mer-m843561174356138155-18.41
ADediting_1556067chr19_40282625_-ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-641chr12435515243551587mer-m843551384355159147-12.84
ADediting_1631458chr19_40282624_-ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-641chr12435515243551587mer-m843551384355159147-12.84
ADediting_1643790chr3_121049689_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-5682chr12435612643561327mer-m843561104356133149-18.83
ADediting_291761chr11_93733708_-ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-1304-3pchr12435444943544557mer-m843544354354456151-21.69
ADediting_291761chr11_93733708_-ENSG00000078237.7ENST00000635110.1TIGAR-204hsa-miR-1304-3pchr12435444943544557mer-m843544354354456151-21.69
ADediting_843620chr2_207754818_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-4775chr12435954643595527mer-m843595324359553150-10.37
ADediting_98288chr1_32086990_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-5585-3pchr12435557843555858mer-1a43555644355585149-10.53
ADediting_98288chr1_32086990_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-5585-3pchr12435695043569567mer-m843569354356957147-14.45
ADediting_98289chr1_32086992_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-5585-3pchr12435557843555858mer-1a43555644355585149-10.53
ADediting_98289chr1_32086992_+ENSG00000078237.7ENST00000179259.6TIGAR-201hsa-miR-5585-3pchr12435695043569567mer-m843569354356957147-14.45

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for TIGAR

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000635110.1protein_codingSoverviewSoverview
ENST00000179259.6protein_codingSoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_344735ENST00000635110.1chr12_4353565_+2649-1072.80-1073.50-1083.90
ADediting_344736ENST00000635110.1chr12_4353582_+2666-1074.30-1073.50-1083.90
ADediting_344737ENST00000635110.1chr12_4353625_+2709-1072.80-1073.50-1083.90
ADediting_344738ENST00000635110.1chr12_4353634_+2718-1075.20-1073.50-1083.90
ADediting_344739ENST00000635110.1chr12_4353671_+2755-1075.80-1073.50-1083.90
ADediting_344740ENST00000635110.1chr12_4353700_+2784-1077.70-1073.50-1083.90
ADediting_344741ENST00000635110.1chr12_4353713_+2797-1074.00-1073.50-1083.90
ADediting_344742ENST00000635110.1chr12_4353714_+2798-1073.50-1073.50-1083.90
ADediting_344743ENST00000635110.1chr12_4353740_+2824-1077.80-1073.50-1083.90
ADediting_344744ENST00000635110.1chr12_4353755_+2839-1077.00-1073.50-1083.90
ADediting_344745ENST00000635110.1chr12_4353809_+2893-1074.50-1073.50-1083.90
ADediting_344735ENST00000179259.6chr12_4353565_+1746-2612.00-2609.00-2652.30
ADediting_344736ENST00000179259.6chr12_4353582_+1763-2609.00-2609.00-2652.30
ADediting_344737ENST00000179259.6chr12_4353625_+1806-2608.30-2609.00-2652.30
ADediting_344738ENST00000179259.6chr12_4353634_+1815-2609.70-2609.00-2652.30
ADediting_344739ENST00000179259.6chr12_4353671_+1852-2610.70-2609.00-2652.30
ADediting_344740ENST00000179259.6chr12_4353700_+1881-2610.00-2609.00-2652.30
ADediting_344741ENST00000179259.6chr12_4353713_+1894-2608.10-2609.00-2652.30
ADediting_344742ENST00000179259.6chr12_4353714_+1895-2612.00-2609.00-2652.30
ADediting_344743ENST00000179259.6chr12_4353740_+1921-2613.10-2609.00-2652.30
ADediting_344744ENST00000179259.6chr12_4353755_+1936-2610.10-2609.00-2652.30
ADediting_344745ENST00000179259.6chr12_4353809_+1990-2612.40-2609.00-2652.30
ADediting_344746ENST00000179259.6chr12_4354788_+2969-2615.20-2609.00-2652.30
ADediting_344747ENST00000179259.6chr12_4354796_+2977-2605.40-2609.00-2652.30
ADediting_344748ENST00000179259.6chr12_4354806_+2987-2608.60-2609.00-2652.30
ADediting_344749ENST00000179259.6chr12_4354812_+2993-2608.70-2609.00-2652.30
ADediting_344750ENST00000179259.6chr12_4354831_+3012-2609.70-2609.00-2652.30
ADediting_344751ENST00000179259.6chr12_4354832_+3013-2611.60-2609.00-2652.30
ADediting_344752ENST00000179259.6chr12_4354835_+3016-2611.80-2609.00-2652.30
ADediting_344753ENST00000179259.6chr12_4354849_+3030-2608.30-2609.00-2652.30
ADediting_344754ENST00000179259.6chr12_4354861_+3042-2608.70-2609.00-2652.30
ADediting_344755ENST00000179259.6chr12_4354871_+3052-2609.00-2609.00-2652.30
ADediting_344756ENST00000179259.6chr12_4354914_+3095-2615.60-2609.00-2652.30
ADediting_344757ENST00000179259.6chr12_4354940_+3121-2608.30-2609.00-2652.30
ADediting_344758ENST00000179259.6chr12_4354974_+3155-2612.90-2609.00-2652.30
ADediting_344759ENST00000179259.6chr12_4354992_+3173-2609.10-2609.00-2652.30
ADediting_344760ENST00000179259.6chr12_4354993_+3174-2608.70-2609.00-2652.30
ADediting_344761ENST00000179259.6chr12_4355011_+3192-2613.00-2609.00-2652.30
ADediting_344762ENST00000179259.6chr12_4355014_+3195-2609.00-2609.00-2652.30
ADediting_344763ENST00000179259.6chr12_4357871_+6052-2612.40-2609.00-2652.30
ADediting_344764ENST00000179259.6chr12_4357879_+6060-2613.70-2609.00-2652.30
ADediting_344765ENST00000179259.6chr12_4357920_+6101-2612.80-2609.00-2652.30
ADediting_344766ENST00000179259.6chr12_4357983_+6164-2608.70-2609.00-2652.30
ADediting_344767ENST00000179259.6chr12_4358054_+6235-2608.70-2609.00-2652.30
ADediting_344768ENST00000179259.6chr12_4358188_+6369-2609.00-2609.00-2652.30
ADediting_344769ENST00000179259.6chr12_4358211_+6392-2609.00-2609.00-2652.30
ADediting_344770ENST00000179259.6chr12_4358220_+6401-2609.00-2609.00-2652.30
ADediting_344771ENST00000179259.6chr12_4358235_+6416-2609.00-2609.00-2652.30

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for TIGAR

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_344666chr12_4327262_+0.0101022413887453-0.1459041772898722.72467979562944e-05-0.2358616170724581.53015611228049e-080.314443560225216
DLPFCADediting_344678chr12_4327807_+0.411921065458483-0.04676569052200110.0116534359059244-0.1431065683046346.3551523046133e-110.360099881834726
DLPFCADediting_344681chr12_4327865_+0.75094051529525-0.01809871578413440.0395895433960589-0.1169579329305942.08120234171925e-100.350832581946512
DLPFCADediting_344692chr12_4337247_+0.2946160675919670.05971327470515810.734929785153127-0.01930597689588172.06549189562639e-080.31171423925313
DLPFCADediting_344698chr12_4337388_+0.339672301949250.05440935105622590.0845233759220266-0.09813453402689746.79822571675758e-180.463225770490855
DLPFCADediting_344700chr12_4337394_+0.6559741305297380.02539999504382640.0233334346863119-0.1287931813007132.61018772526743e-200.492088983606393
DLPFCADediting_344702chr12_4337412_+0.482573459934091-0.04002625968482330.00735256558672774-0.1519674310727352.95961664679202e-090.328923537699998
DLPFCADediting_344708chr12_4337929_+0.1659228353131730.07888280413989540.412880431304751-0.04666990407877678.50976827113356e-160.435738094224481
DLPFCADediting_344714chr12_4337980_+0.7197426637864740.02045914288697660.293694219848724-0.05982719527720991.58458880673513e-090.334235852343087
DLPFCADediting_344717chr12_4337988_+0.4811368026133030.04015759477407370.456873646619306-0.04240893306773034.93497699301821e-090.324498671341892
DLPFCADediting_344722chr12_4347904_+0.3357437636896890.05485293934159680.127131256144162-0.08683035894427671.90748753776157e-230.525893318697021

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC2.94766694522927e-580.7544006512338855.77185318963103e-390.6523713944658858.88801332112634e-140.406695593738979
AC2.04044119277863e-540.7891379169090492.31534985800598e-370.6947664653128648.91521551400982e-180.507582152920696
PCC8.85344762297452e-320.7197604227563553.22070730082308e-450.8076017383264680.1849999447847960.0963201147738464
CER1.18693800583384e-160.6099280178201362.11049643778272e-090.4646016737767950.1481369268582160.118652178268228
TCX7.92669952874461e-370.8145647108396198.47941827258814e-120.5206963098156120.05936587623256360.154315757562608
FP1.09164104064547e-150.5536892209128896.46335731993782e-140.5235468999627440.2614271923524890.0846193259652807
IFG0.0003967423069327040.6534904707737164.76148438639761e-050.721112003385140.09396086587676320.342290925932648
PG7.03408356223062e-420.7954342934638181.83338816757181e-240.6581780672081470.448508448626439-0.055905614844954
STG5.23665097986176e-120.6650082701823691.92307420430615e-110.6515581218904880.600121577363695-0.0580188397268298

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Relation with AD stages for TIGAR

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
TCX0.001390465901277580.30660517702391

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RelatedDrugs for TIGAR

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for TIGAR

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource