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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for YAE1

check button Gene summary
Gene informationGene symbol

YAE1

Gene ID

57002

Gene nameYAE1 maturation factor of ABCE1
SynonymsC7orf36|CIAB2|GK003|YAE1D1
Cytomap

7p14.1

Type of geneprotein-coding
Descriptionprotein YAE1 homologYAE1, ABCE1 maturation factorYae1 domain containing 1yae1 domain-containing protein 1
Modification date20200313
UniProtAcc

Q9NRH1,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
YAE1

GO:0106035

protein maturation by [4Fe-4S] cluster transfer

26182403


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RNA A-to-I events for YAE1

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_1329256(39574336, +), ADediting_1329257(39574342, +), ADediting_1329258(39574343, +), ADediting_1329259(39574349, +), ADediting_1329260(39574369, +), ADediting_1329261(39574389, +), ADediting_1329262(39574396, +), ADediting_1329263(39574397, +), ADediting_1329264(39574416, +), ADediting_1329265(39574433, +), ADediting_1329266(39574437, +), ADediting_1329267(39574461, +), ADediting_1329268(39574477, +), ADediting_1329269(39574478, +), ADediting_1329270(39574484, +), ADediting_1329271(39574499, +), ADediting_1329272(39574500, +), ADediting_1329273(39574501, +), ADediting_1329274(39574504, +), ADediting_1329275(39574531, +), ADediting_1329276(39574532, +), ADediting_1329277(39574555, +), ADediting_1329278(39574557, +), ADediting_1329279(39574572, +), ADediting_1329280(39574581, +), ADediting_1329281(39574590, +), ADediting_1329282(39574613, +), ADediting_1329283(39574662, +), ADediting_1329284(39574674, +), ADediting_1329285(39574682, +), ADediting_1329286(39574683, +), ADediting_1329287(39574696, +), ADediting_1329288(39574721, +), ADediting_1329289(39574775, +), ADediting_1329290(39574784, +), ADediting_1329291(39574802, +), ADediting_1329292(39574820, +), ADediting_1329293(39574825, +), ADediting_1329294(39574860, +), ADediting_1329295(39576925, +), ADediting_1329296(39576939, +), ADediting_1329297(39576950, +), ADediting_1329298(39576951, +), ADediting_1329299(39576959, +), ADediting_1329300(39576969, +), ADediting_1329301(39576972, +), ADediting_1329302(39576975, +), ADediting_1329303(39576995, +), ADediting_1329304(39577012, +), ADediting_1329305(39577034, +), ADediting_1329306(39577036, +), ADediting_1329307(39577050, +), ADediting_1329308(39577076, +), ADediting_1329309(39577079, +), ADediting_1329310(39577081, +), ADediting_1329311(39577096, +), ADediting_1329312(39577116, +), ADediting_1329313(39577117, +), ADediting_1329314(39577130, +), ADediting_1329315(39577157, +), ADediting_1329316(39577158, +), ADediting_1329317(39577170, +), ADediting_1329318(39579468, +), ADediting_1329319(39579781, +), ADediting_1329320(39579804, +), ADediting_1329321(39579852, +), ADediting_1329322(39579924, +), ADediting_1329323(39579942, +), ADediting_1329324(39580020, +), ADediting_1329325(39580412, +), ADediting_1329326(39580415, +), ADediting_1329327(39580433, +), ADediting_1329328(39580439, +), ADediting_1329329(39580445, +), ADediting_1329330(39580446, +), ADediting_1329331(39580449, +), ADediting_1329332(39580452, +), ADediting_1329333(39580453, +), ADediting_1329334(39580456, +), ADediting_1329335(39580462, +), ADediting_1329336(39581608, +), ADediting_1329337(39581614, +), ADediting_1329338(39581616, +), ADediting_1329339(39581617, +), ADediting_1329340(39581625, +), ADediting_1329341(39581634, +), ADediting_1329342(39581652, +), ADediting_1329343(39581658, +), ADediting_1329344(39581663, +), ADediting_1329345(39581670, +), ADediting_1329346(39581671, +), ADediting_1329347(39581676, +), ADediting_1329348(39581686, +), ADediting_1329349(39581690, +), ADediting_1329350(39581724, +), ADediting_1329351(39581725, +), ADediting_1329352(39581748, +), ADediting_1329353(39581756, +), ADediting_1329354(39581757, +), ADediting_1329355(39581760, +), ADediting_1329356(39581774, +), ADediting_1329357(39581778, +), ADediting_1329358(39581780, +), ADediting_1329359(39581781, +), ADediting_1329360(39581791, +), ADediting_1329361(39581792, +), ADediting_1329362(39581797, +), ADediting_1329363(39581805, +), ADediting_1329364(39581806, +), ADediting_1329365(39581851, +), ADediting_1329366(39581852, +), ADediting_1329367(39581944, +), ADediting_1329368(39581959, +), ADediting_1329369(39581967, +), ADediting_1329370(39581971, +), ADediting_1329371(39581989, +), ADediting_1329372(39581992, +), ADediting_1329373(39581997, +), ADediting_1329374(39582013, +), ADediting_1329375(39582027, +), ADediting_1329376(39582028, +), ADediting_1329377(39582031, +), ADediting_1329378(39582032, +), ADediting_1329379(39582045, +), ADediting_1329380(39582054, +), ADediting_1329381(39582057, +), ADediting_1329382(39582069, +), ADediting_1329383(39582103, +), ADediting_1329384(39582107, +), ADediting_1329385(39582181, +), ADediting_1329386(39582222, +), ADediting_1329387(39582247, +), ADediting_1329388(39582252, +), ADediting_1329389(39582255, +), ADediting_1329390(39582268, +), ADediting_1329391(39582295, +), ADediting_1329392(39582313, +), ADediting_1329393(39598163, +), ADediting_1587402(39574402, +), ADediting_1587403(39574547, +), ADediting_1587404(39574556, +), ADediting_1587405(39574830, +), ADediting_1587406(39576913, +), ADediting_1587407(39576958, +), ADediting_1587408(39577105, +), ADediting_1587409(39579473, +), ADediting_1587410(39579965, +), ADediting_1587411(39580414, +), ADediting_1587412(39581622, +), ADediting_1587413(39581685, +), ADediting_1587414(39581688, +), ADediting_1587415(39581720, +), ADediting_1587416(39581721, +), ADediting_1587417(39581768, +), ADediting_1587418(39581832, +),

Top

RNA editing positional annotations for YAE1 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_1329256chr7_39574336_+intronic
ADediting_1329257chr7_39574342_+intronic
ADediting_1329258chr7_39574343_+intronic
ADediting_1329259chr7_39574349_+intronic
ADediting_1329260chr7_39574369_+intronic
ADediting_1329261chr7_39574389_+intronic
ADediting_1329262chr7_39574396_+intronic
ADediting_1329263chr7_39574397_+intronic
ADediting_1329264chr7_39574416_+intronic
ADediting_1329265chr7_39574433_+intronic
ADediting_1329266chr7_39574437_+intronic
ADediting_1329267chr7_39574461_+intronic
ADediting_1329268chr7_39574477_+intronic
ADediting_1329269chr7_39574478_+intronic
ADediting_1329270chr7_39574484_+intronic
ADediting_1329271chr7_39574499_+intronic
ADediting_1329272chr7_39574500_+intronic
ADediting_1329273chr7_39574501_+intronic
ADediting_1329274chr7_39574504_+intronic
ADediting_1329275chr7_39574531_+intronic
ADediting_1329276chr7_39574532_+intronic
ADediting_1329277chr7_39574555_+intronic
ADediting_1329278chr7_39574557_+intronic
ADediting_1329279chr7_39574572_+intronic
ADediting_1329280chr7_39574581_+intronic
ADediting_1329281chr7_39574590_+intronic
ADediting_1329282chr7_39574613_+intronic
ADediting_1329283chr7_39574662_+intronic
ADediting_1329284chr7_39574674_+intronic
ADediting_1329285chr7_39574682_+intronic
ADediting_1329286chr7_39574683_+intronic
ADediting_1329287chr7_39574696_+intronic
ADediting_1329288chr7_39574721_+intronic
ADediting_1329289chr7_39574775_+intronic
ADediting_1329290chr7_39574784_+intronic
ADediting_1329291chr7_39574802_+intronic
ADediting_1329292chr7_39574820_+intronic
ADediting_1329293chr7_39574825_+intronic
ADediting_1329294chr7_39574860_+intronic
ADediting_1329295chr7_39576925_+intronic
ADediting_1329296chr7_39576939_+intronic
ADediting_1329297chr7_39576950_+intronic
ADediting_1329298chr7_39576951_+intronic
ADediting_1329299chr7_39576959_+intronic
ADediting_1329300chr7_39576969_+intronic
ADediting_1329301chr7_39576972_+intronic
ADediting_1329302chr7_39576975_+intronic
ADediting_1329303chr7_39576995_+intronic
ADediting_1329304chr7_39577012_+intronic
ADediting_1329305chr7_39577034_+intronic
ADediting_1329306chr7_39577036_+intronic
ADediting_1329307chr7_39577050_+intronic
ADediting_1329308chr7_39577076_+intronic
ADediting_1329309chr7_39577079_+intronic
ADediting_1329310chr7_39577081_+intronic
ADediting_1329311chr7_39577096_+intronic
ADediting_1329312chr7_39577116_+intronic
ADediting_1329313chr7_39577117_+intronic
ADediting_1329314chr7_39577130_+intronic
ADediting_1329315chr7_39577157_+intronic
ADediting_1329316chr7_39577158_+intronic
ADediting_1329317chr7_39577170_+intronic
ADediting_1329318chr7_39579468_+intronic
ADediting_1329319chr7_39579781_+intronic
ADediting_1329320chr7_39579804_+intronic
ADediting_1329321chr7_39579852_+intronic
ADediting_1329322chr7_39579924_+intronic
ADediting_1329323chr7_39579942_+intronic
ADediting_1329324chr7_39580020_+intronic
ADediting_1329325chr7_39580412_+intronic
ADediting_1329326chr7_39580415_+intronic
ADediting_1329327chr7_39580433_+intronic
ADediting_1329328chr7_39580439_+intronic
ADediting_1329329chr7_39580445_+intronic
ADediting_1329330chr7_39580446_+intronic
ADediting_1329331chr7_39580449_+intronic
ADediting_1329332chr7_39580452_+intronic
ADediting_1329333chr7_39580453_+intronic
ADediting_1329334chr7_39580456_+intronic
ADediting_1329335chr7_39580462_+intronic
ADediting_1329336chr7_39581608_+intronic
ADediting_1329337chr7_39581614_+intronic
ADediting_1329338chr7_39581616_+intronic
ADediting_1329339chr7_39581617_+intronic
ADediting_1329340chr7_39581625_+intronic
ADediting_1329341chr7_39581634_+intronic
ADediting_1329342chr7_39581652_+intronic
ADediting_1329343chr7_39581658_+intronic
ADediting_1329344chr7_39581663_+intronic
ADediting_1329345chr7_39581670_+intronic
ADediting_1329346chr7_39581671_+intronic
ADediting_1329347chr7_39581676_+intronic
ADediting_1329348chr7_39581686_+intronic
ADediting_1329349chr7_39581690_+intronic
ADediting_1329350chr7_39581724_+intronic
ADediting_1329351chr7_39581725_+intronic
ADediting_1329352chr7_39581748_+intronic
ADediting_1329353chr7_39581756_+intronic
ADediting_1329354chr7_39581757_+intronic
ADediting_1329355chr7_39581760_+intronic
ADediting_1329356chr7_39581774_+intronic
ADediting_1329357chr7_39581778_+intronic
ADediting_1329358chr7_39581780_+intronic
ADediting_1329359chr7_39581781_+intronic
ADediting_1329360chr7_39581791_+intronic
ADediting_1329361chr7_39581792_+intronic
ADediting_1329362chr7_39581797_+intronic
ADediting_1329363chr7_39581805_+intronic
ADediting_1329364chr7_39581806_+intronic
ADediting_1329365chr7_39581851_+intronic
ADediting_1329366chr7_39581852_+intronic
ADediting_1329367chr7_39581944_+intronic
ADediting_1329368chr7_39581959_+intronic
ADediting_1329369chr7_39581967_+intronic
ADediting_1329370chr7_39581971_+intronic
ADediting_1329371chr7_39581989_+intronic
ADediting_1329372chr7_39581992_+intronic
ADediting_1329373chr7_39581997_+intronic
ADediting_1329374chr7_39582013_+intronic
ADediting_1329375chr7_39582027_+intronic
ADediting_1329376chr7_39582028_+intronic
ADediting_1329377chr7_39582031_+intronic
ADediting_1329378chr7_39582032_+intronic
ADediting_1329379chr7_39582045_+intronic
ADediting_1329380chr7_39582054_+intronic
ADediting_1329381chr7_39582057_+intronic
ADediting_1329382chr7_39582069_+intronic
ADediting_1329383chr7_39582103_+intronic
ADediting_1329384chr7_39582107_+intronic
ADediting_1329385chr7_39582181_+intronic
ADediting_1329386chr7_39582222_+intronic
ADediting_1329387chr7_39582247_+intronic
ADediting_1329388chr7_39582252_+intronic
ADediting_1329389chr7_39582255_+intronic
ADediting_1329390chr7_39582268_+intronic
ADediting_1329391chr7_39582295_+intronic
ADediting_1329392chr7_39582313_+intronic
ADediting_1329393chr7_39598163_+intronic
ADediting_1587402chr7_39574402_+intronic
ADediting_1587403chr7_39574547_+intronic
ADediting_1587404chr7_39574556_+intronic
ADediting_1587405chr7_39574830_+intronic
ADediting_1587406chr7_39576913_+intronic
ADediting_1587407chr7_39576958_+intronic
ADediting_1587408chr7_39577105_+intronic
ADediting_1587409chr7_39579473_+intronic
ADediting_1587410chr7_39579965_+intronic
ADediting_1587411chr7_39580414_+intronic
ADediting_1587412chr7_39581622_+intronic
ADediting_1587413chr7_39581685_+intronic
ADediting_1587414chr7_39581688_+intronic
ADediting_1587415chr7_39581720_+intronic
ADediting_1587416chr7_39581721_+intronic
ADediting_1587417chr7_39581768_+intronic
ADediting_1587418chr7_39581832_+intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_1329256chr7_39574336_+SINEAluName=AluJr
ADediting_1329257chr7_39574342_+SINEAluName=AluJr
ADediting_1329258chr7_39574343_+SINEAluName=AluJr
ADediting_1329259chr7_39574349_+SINEAluName=AluJr
ADediting_1329260chr7_39574369_+SINEAluName=AluJr
ADediting_1329261chr7_39574389_+SINEAluName=AluJr
ADediting_1329262chr7_39574396_+SINEAluName=AluJr
ADediting_1329263chr7_39574397_+SINEAluName=AluJr
ADediting_1329264chr7_39574416_+SINEAluName=AluJr
ADediting_1329265chr7_39574433_+SINEAluName=AluJr
ADediting_1329266chr7_39574437_+SINEAluName=AluJr
ADediting_1329267chr7_39574461_+SINEAluName=AluSx
ADediting_1329268chr7_39574477_+SINEAluName=AluSx
ADediting_1329269chr7_39574478_+SINEAluName=AluSx
ADediting_1329270chr7_39574484_+SINEAluName=AluSx
ADediting_1329271chr7_39574499_+SINEAluName=AluSx
ADediting_1329272chr7_39574500_+SINEAluName=AluSx
ADediting_1329273chr7_39574501_+SINEAluName=AluSx
ADediting_1329274chr7_39574504_+SINEAluName=AluSx
ADediting_1329275chr7_39574531_+SINEAluName=AluSx
ADediting_1329276chr7_39574532_+SINEAluName=AluSx
ADediting_1329277chr7_39574555_+SINEAluName=AluSx
ADediting_1329278chr7_39574557_+SINEAluName=AluSx
ADediting_1329279chr7_39574572_+SINEAluName=AluSx
ADediting_1329280chr7_39574581_+SINEAluName=AluSx
ADediting_1329281chr7_39574590_+SINEAluName=AluSx
ADediting_1329282chr7_39574613_+SINEAluName=AluSx
ADediting_1329283chr7_39574662_+SINEAluName=AluSx
ADediting_1329284chr7_39574674_+SINEAluName=AluSx
ADediting_1329285chr7_39574682_+SINEAluName=AluSx
ADediting_1329286chr7_39574683_+SINEAluName=AluSx
ADediting_1329287chr7_39574696_+SINEAluName=AluSx
ADediting_1329288chr7_39574721_+SINEAluName=AluSx
ADediting_1329289chr7_39574775_+SINEAluName=AluJr
ADediting_1329290chr7_39574784_+SINEAluName=AluJr
ADediting_1329291chr7_39574802_+SINEAluName=AluJr
ADediting_1329292chr7_39574820_+SINEAluName=AluJr
ADediting_1329293chr7_39574825_+SINEAluName=AluJr
ADediting_1329294chr7_39574860_+SINEAluName=AluJr
ADediting_1329295chr7_39576925_+SINEAluName=AluSq2
ADediting_1329296chr7_39576939_+SINEAluName=AluSq2
ADediting_1329297chr7_39576950_+SINEAluName=AluSq2
ADediting_1329298chr7_39576951_+SINEAluName=AluSq2
ADediting_1329299chr7_39576959_+SINEAluName=AluSq2
ADediting_1329300chr7_39576969_+SINEAluName=AluSq2
ADediting_1329301chr7_39576972_+SINEAluName=AluSq2
ADediting_1329302chr7_39576975_+SINEAluName=AluSq2
ADediting_1329303chr7_39576995_+SINEAluName=AluSq2
ADediting_1329304chr7_39577012_+SINEAluName=AluSq2
ADediting_1329305chr7_39577034_+SINEAluName=AluSq2
ADediting_1329306chr7_39577036_+SINEAluName=AluSq2
ADediting_1329307chr7_39577050_+SINEAluName=AluSq2
ADediting_1329308chr7_39577076_+SINEAluName=AluSq2
ADediting_1329309chr7_39577079_+SINEAluName=AluSq2
ADediting_1329310chr7_39577081_+SINEAluName=AluSq2
ADediting_1329311chr7_39577096_+SINEAluName=AluSq2
ADediting_1329312chr7_39577116_+SINEAluName=AluSq2
ADediting_1329313chr7_39577117_+SINEAluName=AluSq2
ADediting_1329314chr7_39577130_+SINEAluName=AluSq2
ADediting_1329315chr7_39577157_+SINEAluName=AluSq2
ADediting_1329316chr7_39577158_+SINEAluName=AluSq2
ADediting_1329317chr7_39577170_+SINEAluName=AluSq2
ADediting_1329318chr7_39579468_+SINEAluName=AluSx1
ADediting_1329319chr7_39579781_+SINEAluName=AluJb
ADediting_1329320chr7_39579804_+SINEAluName=AluJb
ADediting_1329321chr7_39579852_+SINEAluName=AluJb
ADediting_1329322chr7_39579924_+SINEAluName=AluJb
ADediting_1329323chr7_39579942_+SINEAluName=AluJb
ADediting_1329324chr7_39580020_+SINEAluName=AluJb
ADediting_1329336chr7_39581608_+SINEAluName=AluJo
ADediting_1329337chr7_39581614_+SINEAluName=AluJo
ADediting_1329338chr7_39581616_+SINEAluName=AluJo
ADediting_1329339chr7_39581617_+SINEAluName=AluJo
ADediting_1329340chr7_39581625_+SINEAluName=AluJo
ADediting_1329341chr7_39581634_+SINEAluName=AluJo
ADediting_1329342chr7_39581652_+SINEAluName=AluJo
ADediting_1329343chr7_39581658_+SINEAluName=AluJo
ADediting_1329344chr7_39581663_+SINEAluName=AluJo
ADediting_1329345chr7_39581670_+SINEAluName=AluJo
ADediting_1329346chr7_39581671_+SINEAluName=AluJo
ADediting_1329347chr7_39581676_+SINEAluName=AluJo
ADediting_1329348chr7_39581686_+SINEAluName=AluJo
ADediting_1329349chr7_39581690_+SINEAluName=AluJo
ADediting_1329350chr7_39581724_+SINEAluName=AluJo
ADediting_1329351chr7_39581725_+SINEAluName=AluJo
ADediting_1329352chr7_39581748_+SINEAluName=AluJo
ADediting_1329353chr7_39581756_+SINEAluName=AluJo
ADediting_1329354chr7_39581757_+SINEAluName=AluJo
ADediting_1329355chr7_39581760_+SINEAluName=AluJo
ADediting_1329356chr7_39581774_+SINEAluName=AluJo
ADediting_1329357chr7_39581778_+SINEAluName=AluJo
ADediting_1329358chr7_39581780_+SINEAluName=AluJo
ADediting_1329359chr7_39581781_+SINEAluName=AluJo
ADediting_1329360chr7_39581791_+SINEAluName=AluJo
ADediting_1329361chr7_39581792_+SINEAluName=AluJo
ADediting_1329362chr7_39581797_+SINEAluName=AluJo
ADediting_1329363chr7_39581805_+SINEAluName=AluJo
ADediting_1329364chr7_39581806_+SINEAluName=AluJo
ADediting_1329365chr7_39581851_+SINEAluName=AluJo
ADediting_1329366chr7_39581852_+SINEAluName=AluJo
ADediting_1329367chr7_39581944_+SINEAluName=AluJb
ADediting_1329368chr7_39581959_+SINEAluName=AluJb
ADediting_1329369chr7_39581967_+SINEAluName=AluJb
ADediting_1329370chr7_39581971_+SINEAluName=AluJb
ADediting_1329371chr7_39581989_+SINEAluName=AluJb
ADediting_1329372chr7_39581992_+SINEAluName=AluJb
ADediting_1329373chr7_39581997_+SINEAluName=AluJb
ADediting_1329374chr7_39582013_+SINEAluName=AluJb
ADediting_1329375chr7_39582027_+SINEAluName=AluJb
ADediting_1329376chr7_39582028_+SINEAluName=AluJb
ADediting_1329377chr7_39582031_+SINEAluName=AluJb
ADediting_1329378chr7_39582032_+SINEAluName=AluJb
ADediting_1329379chr7_39582045_+SINEAluName=AluJb
ADediting_1329380chr7_39582054_+SINEAluName=AluJb
ADediting_1329381chr7_39582057_+SINEAluName=AluJb
ADediting_1329382chr7_39582069_+SINEAluName=AluJb
ADediting_1329385chr7_39582181_+SINEAluName=AluJb
ADediting_1329386chr7_39582222_+SINEAluName=AluJb
ADediting_1329387chr7_39582247_+SINEAluName=AluJb
ADediting_1329388chr7_39582252_+SINEAluName=AluJb
ADediting_1329389chr7_39582255_+SINEAluName=AluJb
ADediting_1329390chr7_39582268_+SINEAluName=AluJb
ADediting_1329391chr7_39582295_+SINEAluName=AluJb
ADediting_1329392chr7_39582313_+SINEAluName=AluJb
ADediting_1329393chr7_39598163_+SINEAluName=AluSz
ADediting_1587402chr7_39574402_+SINEAluName=AluJr
ADediting_1587403chr7_39574547_+SINEAluName=AluSx
ADediting_1587404chr7_39574556_+SINEAluName=AluSx
ADediting_1587405chr7_39574830_+SINEAluName=AluJr
ADediting_1587406chr7_39576913_+SINEAluName=AluSq2
ADediting_1587407chr7_39576958_+SINEAluName=AluSq2
ADediting_1587408chr7_39577105_+SINEAluName=AluSq2
ADediting_1587409chr7_39579473_+SINEAluName=AluSx1
ADediting_1587410chr7_39579965_+SINEAluName=AluJb
ADediting_1587412chr7_39581622_+SINEAluName=AluJo
ADediting_1587413chr7_39581685_+SINEAluName=AluJo
ADediting_1587414chr7_39581688_+SINEAluName=AluJo
ADediting_1587415chr7_39581720_+SINEAluName=AluJo
ADediting_1587416chr7_39581721_+SINEAluName=AluJo
ADediting_1587417chr7_39581768_+SINEAluName=AluJo
ADediting_1587418chr7_39581832_+SINEAluName=AluJo

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RNA A-to-I editing events in the alternative splicing sites for YAE1

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for YAE1

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for YAE1

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for YAE1


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1471003chr9_63819626_+ENSG00000241127.8ENST00000432096.2YAE1-202hsa-miR-4477bchr739610176396101827mer-m83961016339610183152-11.39

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_843620chr2_207754818_+ENSG00000241127.8ENST00000223273.7YAE1-201hsa-miR-4775chr739572827395728337mer-1a3957281239572833140-9.19
ADediting_843620chr2_207754818_+ENSG00000241127.8ENST00000223273.7YAE1-201hsa-miR-4775chr739572847395728548mer-1a3957283339572854140-4.98

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for YAE1

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for YAE1

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
CERADediting_1329259chr7_39574349_+0.002419701344121070.2459030529146562.57640600083271e-060.3730826325051980.00174700106675990.25351030938205
CERADediting_1329260chr7_39574369_+4.8434282829166e-050.3253949369798239.8973326972016e-080.4184463468651030.2633748207797890.0918964384601739
CERADediting_1329261chr7_39574389_+0.0152643211301240.1977795783808317.89512878131375e-060.3557787956666130.8827788189873940.0121401521910256
CERADediting_1329263chr7_39574397_+0.01049606513928710.208389164909116.05898597425275e-070.3940661839222440.5786335329182040.0457053730790904
CERADediting_1329264chr7_39574416_+1.72169869733964e-060.3790740395594381.28994212989885e-080.4437404263327790.5926513855954830.0440295209450545
CERADediting_1329265chr7_39574433_+0.0002342171883811420.2960957260495472.25880931514648e-050.3385599340505640.5424660161124590.0501198440282878
CERADediting_1329270chr7_39574484_+0.0005938340728968890.2772211488042171.46128301228216e-050.3458171221065990.327638617034442-0.0804687856063659
CERADediting_1329271chr7_39574499_+0.0009035542637990960.2682511748171121.37424604476207e-060.3823732439202280.17895820044140.110322286033008
CERADediting_1329274chr7_39574504_+0.0003714277211113280.2869050789117888.76030393882547e-060.3541197138989720.5115034464231140.0540155891624849
CERADediting_1329275chr7_39574531_+9.50148707245359e-050.3132396413109473.299439381527e-050.3320952486787720.05032212696053120.160112858371397
CERADediting_1329278chr7_39574557_+0.0001306852430505690.3073021874208796.3845431842701e-060.3591384890559220.04274995907601380.165674889436088
CERADediting_1329283chr7_39574662_+1.23042687578271e-060.3839781728350446.66580298018855e-090.4515116913674540.09139040132561470.13832722573684
CERADediting_1329284chr7_39574674_+0.001521024181618670.2566776644611713.1621592451967e-070.4030412258984970.7571278484502210.0254594198807311
CERADediting_1329285chr7_39574682_+2.93955605294749e-060.3710964097131332.62249719863751e-090.4621713463684070.2959847958595480.0858913539120583
TCXADediting_1329285chr7_39574682_+0.2078678305363550.1034228444561130.0001293331951179990.3074978976224890.624813321347151-0.0402504813029821
CERADediting_1329287chr7_39574696_+3.90231579396729e-070.400167289206091.87203730751961e-100.490491761346970.09899731352056730.13521202678848
TCXADediting_1329287chr7_39574696_+0.002541411985053560.2447368836200787.37101758688969e-070.3913082240654930.998457495958298-0.000159180278134348
CERADediting_1329291chr7_39574802_+1.98301612400973e-060.3769872068110211.95444210499855e-080.4387476790315680.01839919421825980.192296460670294
CERADediting_1329292chr7_39574820_+0.01846250095169090.1921943618710345.65511060265966e-050.3226456010683130.06592380478207560.150551388821825
CERADediting_1329296chr7_39576939_+0.001844946785901380.2522521335606731.70296507116855e-050.343287231102920.05948254803716510.154245873300266
CERADediting_1329297chr7_39576950_+0.0004653958226246480.2822941248949881.98941450696411e-060.376939464204990.02113420691542310.188139238174782
CERADediting_1329298chr7_39576951_+0.002707667934788370.2432230462309814.73451315350277e-050.3257963098421890.04036201863283690.167599985737318
CERADediting_1329317chr7_39577170_+0.003012888000506890.24065046609724.55422066849935e-050.3264801686115630.04465900627184320.16419958610652
CERADediting_1329319chr7_39579781_+0.0001011276472153010.3120880806383783.36423506943424e-080.4320981483012370.01944584955299050.190646156059321
CERADediting_1329321chr7_39579852_+0.00253599589787470.2447876915714927.74591881825323e-070.3906062092454760.006539920210176330.221132768578676
CERADediting_1329323chr7_39579942_+0.002868064212744740.2418402394842972.51989719144774e-070.4061136686797215.07881904544613e-050.324555641406296
CERADediting_1329327chr7_39580433_+1.625161628625e-050.344062519063012.25030745365678e-090.4638859359432740.002356638574105410.24652834693352
CERADediting_1329328chr7_39580439_+1.24583062788775e-070.4154551190749352.69130166866866e-110.509766382083910.001634627945626150.255035459541209
CERADediting_1329329chr7_39580445_+0.0006289786749881750.2760101641235281.2421973146541e-070.4154932654448230.01430899033437870.199646066385334
CERADediting_1329330chr7_39580446_+8.32663129843265e-060.3549309420616694.02884526229805e-100.4825314687799890.0001969454633129410.299472277184944
CERADediting_1329331chr7_39580449_+1.76506961824732e-060.378707676785712.53348449804076e-130.5517025108032790.002617261264105530.244035456621075
CERADediting_1329341chr7_39581634_+0.05859643831825310.1547794838329344.77132858927802e-050.3256596773073027.85201468942918e-050.316732452701251
CERADediting_1329342chr7_39581652_+0.000459302550221330.2825657436549087.53356674550195e-070.3909997596092480.09728552587226890.135896060649764
CERADediting_1329344chr7_39581663_+0.03070738307653540.1765209913852139.45528005361824e-060.3528957013334680.0002003870554452460.299136634585639
CERADediting_1329345chr7_39581670_+0.02063183824674720.1888665353765261.23094818056077e-060.3839720392147587.09330266615535e-050.318576438740546
CERADediting_1329346chr7_39581671_+0.00900798461807380.2125837421784286.04728104206776e-080.4247541528123352.37804878013229e-050.33769068110756
CERADediting_1329347chr7_39581676_+0.01615846610584020.1961226962127181.09515854683437e-060.3856598626317640.000251548581617130.294692880892614
TCXADediting_1329350chr7_39581724_+0.820672830129977-0.01866282943046580.0233682262220445-0.1850751003049095.09667493921639e-050.324493473705496
CERADediting_1329352chr7_39581748_+0.04693051799602250.1625112640718672.1844116524922e-050.3391244617359840.0002588815204791880.294126188631742
CERADediting_1329354chr7_39581757_+0.008516679963293350.2141037634806034.76257047929176e-070.3974198443952880.0007516447584497980.272222326802226
CERADediting_1329355chr7_39581760_+0.0008896140046129180.2685889386694744.14839328005377e-090.4569767697706720.0001094454745524120.310621412757011
CERADediting_1329356chr7_39581774_+0.02884025198757830.1785159981804752.34444328214144e-060.3744957416031960.0059114375746690.2237678672169
CERADediting_1329357chr7_39581778_+0.03841829302126840.1692388675128461.16573238179162e-060.3847592522522470.02002184138994840.189770486140283
CERADediting_1329359chr7_39581781_+0.0161810105509330.1960819621770963.30506349039213e-080.432317684630070.0030524688580570.240334289010022
DLPFCADediting_1329360chr7_39581791_+0.5775169814855010.03175665128929970.132590827786652-0.08560832686275892.09921827559926e-120.385196816767009
CERADediting_1329360chr7_39581791_+0.001063507668896360.2646840576854651.00946440858574e-090.4727146885590260.003436294746153480.237446469923958
DLPFCADediting_1329361chr7_39581792_+0.01228494723285090.1420611612857920.895940881821980.007458439450407615.20086615241678e-090.324040464662453
CERADediting_1329361chr7_39581792_+0.002253622508608280.2475831888409676.37834691375699e-080.4240779028553590.1189773185717730.127844931569202
CERADediting_1329362chr7_39581797_+0.003248667258056250.2388196515337691.92001004646052e-080.4389629103352920.2039644571000860.104312027890719
DLPFCADediting_1329363chr7_39581805_+0.462263357695330.04190323221388410.235085755821297-0.06763348068882616.66835977760167e-080.300777161015446
CERADediting_1329363chr7_39581805_+0.02698091336780580.1806152307597353.73030853943613e-050.3299698214451710.08362333616345790.141728748368266
TCXADediting_1329363chr7_39581805_+0.9036523807536490.009966724348515070.108453024173601-0.1315930656749491.7082576337652e-060.379189361988713
CERADediting_1329364chr7_39581806_+0.001342646488536990.2594970464089583.9688596767262e-100.4826892438489150.02110426322718010.188182168523447
CERADediting_1329368chr7_39581959_+0.1998322291581620.1052668037490493.87518936214805e-050.3293067897165260.008031650206371290.215682499547963
DLPFCADediting_1329369chr7_39581967_+0.01872827786198040.1334632004010350.7113406052817170.02110068197834913.77368594207277e-090.326829451327867
CERADediting_1329370chr7_39581971_+0.05025518977154340.1601588760041461.73623016632047e-070.4110888916619790.07730782621026320.144686572865225
TCXADediting_1329370chr7_39581971_+0.8227823557430140.01843959552082390.0001430576225648390.3055941150612380.9937728281166340.000642625416400334
DLPFCADediting_1329373chr7_39581997_+0.009593128564929390.1469056931043070.5412859885428330.03482521477947893.71565982533123e-110.364196357663471
DLPFCADediting_1329374chr7_39582013_+0.1068405321813840.09176452088346110.5490683022405550.03415787914663787.39328451551985e-100.340583986395866
TCXADediting_1329374chr7_39582013_+0.432704477382391-0.06453308369377260.0112571750242528-0.2064429491487456.7492264143893e-050.319474371720379
DLPFCADediting_1329375chr7_39582027_+0.201401369483020.07275877586306240.8460025973764240.0110754328952131.17138537404674e-100.355360211436327
CERADediting_1329375chr7_39582027_+0.07195211780191730.147351700473827.36023978457555e-050.3179074828700830.04519846856354690.163792249918097
DLPFCADediting_1329376chr7_39582028_+0.0865646925903440.09749937846540820.7690154988927860.01674541032676693.4369625844542e-170.454276640818682
TCXADediting_1329376chr7_39582028_+0.240334155374643-0.09645227647645550.0642908498272331-0.1514590478786670.000148472116468270.304889581270976
CERADediting_1329377chr7_39582031_+0.01701995933761130.1946001234197381.47869847546784e-050.3456220721434880.002555106857631470.244608848888524
DLPFCADediting_1329378chr7_39582032_+0.2292951307068990.06847549512568990.7762255392583930.01620823244212554.36507898466437e-130.396069419028321
CERADediting_1329378chr7_39582032_+0.02352595898401650.1848684214094142.37695004489926e-060.3742899092338880.00543358516357490.225944313753657
DLPFCADediting_1329379chr7_39582045_+0.3013435831188880.05888899858289920.955674142649321-0.003169689495771883.10588586264799e-080.307958026219972
DLPFCADediting_1329382chr7_39582069_+0.1069050230973420.09174771605892830.868975408070320.009406896898826851.29172533905809e-140.419086866164518
TCXADediting_1329382chr7_39582069_+0.0292683219757595-0.1780490996954721.33675216950278e-05-0.3472794095384050.0001047754904326830.311431493372176
CERADediting_1329383chr7_39582103_+0.01009147375196840.209474880539022.51404912085118e-080.4356825667838730.0129982022523990.202392649104196
CERADediting_1329384chr7_39582107_+0.005518829376536730.2255438457491274.05628629074297e-080.4297742683855380.0669393984937740.149996094969504
ACADediting_1329385chr7_39582181_+0.003772796104631150.1825672908311150.213655189086470.07892351897704074.83024364557308e-070.3118980111829
CERADediting_1329387chr7_39582247_+0.3174239795505040.08217981697808520.0001181595848482830.3091925522901510.04018069981348760.167750028890187
CERADediting_1329388chr7_39582252_+0.4083407269132120.06799999837403720.0001673198945216370.3026109364942460.006606019948154970.22086889521094
CERADediting_1329392chr7_39582313_+0.004676421627591520.2297713300652191.2401532701757e-050.3485051815802980.0178753315861390.193153213582668
CERADediting_1587408chr7_39577105_+0.005161911118288240.227259188203634.74507966170541e-050.3257569928015230.0005633578105431890.278325975988167

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC3.08261497287473e-400.660581588280731.78899634559738e-510.7233643850889290.5207005769959890.0366139275628208
AC2.05038256923761e-700.8482546912033671.69791196217411e-440.7393683064782153.10184906974193e-200.538920414007849
PCC2.60208489880649e-360.7538116963881911.55536396687908e-320.7258113794259850.0008158043059056220.240227876598675
CER1.12955775453413e-190.6540952059047295.94558554490197e-070.3943307038459560.7608290383333630.025059255157322
TCX6.26089193160553e-270.7367263240327169.88064316701712e-080.4184681772120276.83986900505079e-060.358052818916214
FP1.87021884434277e-210.6346545952900065.06206835244931e-290.713744227358480.1656746584646540.104354125369876
IFG0.0004640666607886570.6477384041278660.004533982583988550.5484046727502380.930254044630463-0.0184480844263289
PG1.10793295005559e-520.8482534039558951.12482780885396e-310.7254773439970510.771785452153857-0.0214086667701551
STG3.24519565013037e-170.7631118068357548.46225129057757e-160.740326960602990.02608709422914330.242751765668558

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Relation with AD stages for YAE1

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
CERADediting_1329259chr7_39574349_+0.000344855373816650.338126473278859
CERADediting_1329283chr7_39574662_+0.001503007509243290.301785668433703
CERADediting_1329285chr7_39574682_+0.001576347273471770.300530018085224
CERADediting_1329287chr7_39574696_+0.0001150748726681470.362589905689123
CERADediting_1329291chr7_39574802_+0.0009552988893843430.313463523771275
CERADediting_1329319chr7_39579781_+0.000295692282690330.341677062341184
CERADediting_1329321chr7_39579852_+3.91823493279299e-050.384828653734944
CERADediting_1329328chr7_39580439_+0.000111761057001820.363214890716623
CERADediting_1329329chr7_39580445_+8.50236883080674e-050.369002081865591
CERADediting_1329330chr7_39580446_+4.65916653778903e-050.381360441011158
CERADediting_1329331chr7_39580449_+0.000110007219614590.363552670961992
CERADediting_1329341chr7_39581634_+0.0009938300139510060.312463220189656
CERADediting_1329344chr7_39581663_+0.0004924035729502970.329737800945766
CERADediting_1329345chr7_39581670_+0.0005400720276681060.327522092223182
CERADediting_1329346chr7_39581671_+1.33126569357587e-050.405611681141888
CERADediting_1329347chr7_39581676_+3.09137429703612e-050.389512785718859
CERADediting_1329352chr7_39581748_+6.06246445267131e-050.37601232268593
CERADediting_1329354chr7_39581757_+0.0002409303385928310.346340596921268
CERADediting_1329355chr7_39581760_+1.94660744602896e-060.439511935241495
CERADediting_1329356chr7_39581774_+7.50432153785876e-060.41610844448335
CERADediting_1329359chr7_39581781_+0.0001152816917250450.362551456615901
CERADediting_1329360chr7_39581791_+0.0002862678155979250.342419466588599
CERADediting_1329361chr7_39581792_+0.000385347012334750.335537064648309
CERADediting_1329364chr7_39581806_+8.45222779138641e-050.369126062665456
CERADediting_1329368chr7_39581959_+4.24427438083245e-050.383232919748887
CERADediting_1329370chr7_39581971_+3.01260650736191e-050.390018590918425
CERADediting_1329377chr7_39582031_+0.0001275677317939660.360375137819379
CERADediting_1329378chr7_39582032_+0.0001211498305279140.36148641223029
CERADediting_1329383chr7_39582103_+2.29402942795106e-060.436755186492037
CERADediting_1329384chr7_39582107_+0.0002328763851331020.347107802740783
CERADediting_1329392chr7_39582313_+0.001509359161433850.301674746512544
CERADediting_1587408chr7_39577105_+0.001336122653865590.304864250365793
TCXADediting_1329273chr7_39574501_+0.0008820671633680340.318345430100919

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
TCX0.0007294152143469990.323110727840149

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RelatedDrugs for YAE1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for YAE1

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource