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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for PSMG2

check button Gene summary
Gene informationGene symbol

PSMG2

Gene ID

56984

Gene nameproteasome assembly chaperone 2
SynonymsCLAST3|HCCA3|HsT1707|MDS003|PAC2|TNFSF5IP1
Cytomap

18p11.21

Type of geneprotein-coding
Descriptionproteasome assembly chaperone 2CD40 ligand-activated specific transcript 3HDCMC29PHSPC260PAC-2hepatocellular carcinoma susceptibility proteinhepatocellular carcinoma-susceptibility protein 3likely ortholog of mouse CD40 ligand-activated specific tr
Modification date20200313
UniProtAcc

Q969U7,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
PSMG2

GO:0043248

proteasome assembly

16251969


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RNA A-to-I events for PSMG2

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_680393(12659412, +), ADediting_680394(12659413, +), ADediting_680395(12659443, +), ADediting_680396(12659457, +), ADediting_680397(12659481, +), ADediting_680398(12659483, +), ADediting_680399(12659491, +), ADediting_680400(12659523, +), ADediting_680401(12659549, +), ADediting_680402(12659550, +), ADediting_680403(12659559, +), ADediting_680404(12659576, +), ADediting_680405(12659591, +), ADediting_680406(12659605, +), ADediting_680407(12659612, +), ADediting_680408(12659619, +), ADediting_680409(12659620, +), ADediting_680410(12659625, +), ADediting_680411(12659627, +), ADediting_680412(12660346, +), ADediting_680413(12660371, +), ADediting_680414(12660386, +), ADediting_680415(12660391, +), ADediting_680416(12660421, +), ADediting_680417(12660461, +), ADediting_680418(12660519, +), ADediting_680419(12660573, +), ADediting_680420(12660595, +), ADediting_680421(12661030, +), ADediting_680422(12661098, +), ADediting_680423(12661161, +), ADediting_680424(12661210, +), ADediting_680425(12661214, +), ADediting_680426(12661249, +), ADediting_680427(12661263, +), ADediting_680428(12661304, +), ADediting_680429(12661510, +), ADediting_680430(12661534, +), ADediting_680431(12661547, +), ADediting_680432(12661585, +), ADediting_680433(12661586, +), ADediting_680434(12661596, +), ADediting_680435(12661607, +), ADediting_680436(12661628, +), ADediting_680437(12661646, +), ADediting_680438(12661654, +), ADediting_680439(12661655, +), ADediting_680440(12708458, +), ADediting_680441(12709252, +), ADediting_680442(12710845, +), ADediting_680443(12711025, +), ADediting_680444(12713829, +), ADediting_680445(12715635, +), ADediting_680446(12720904, +), ADediting_680447(12720910, +), ADediting_680448(12720911, +), ADediting_680449(12721000, +), ADediting_680450(12721001, +), ADediting_680451(12721003, +), ADediting_680452(12721004, +), ADediting_680453(12721014, +), ADediting_680454(12721017, +), ADediting_680455(12721018, +), ADediting_680456(12721020, +), ADediting_680457(12721021, +), ADediting_680458(12721025, +), ADediting_680459(12721026, +), ADediting_680460(12721029, +), ADediting_680461(12721030, +), ADediting_680462(12721033, +), ADediting_680463(12721059, +), ADediting_680464(12721069, +), ADediting_680465(12721187, +), ADediting_680466(12721190, +), ADediting_680467(12723479, +), ADediting_680468(12723515, +), ADediting_680469(12723531, +), ADediting_680470(12723533, +), ADediting_680471(12723557, +), ADediting_680472(12723564, +), ADediting_680473(12723572, +), ADediting_680474(12723575, +), ADediting_680475(12723579, +), ADediting_680476(12723589, +), ADediting_680477(12723666, +), ADediting_1550271(12659452, +), ADediting_1550272(12659502, +), ADediting_1550273(12659590, +), ADediting_1550274(12661291, +), ADediting_1550275(12713860, +), ADediting_1550276(12713891, +), ADediting_1550277(12713916, +), ADediting_1550278(12715623, +), ADediting_1550279(12715758, +), ADediting_1550280(12715768, +), ADediting_1550281(12721002, +), ADediting_1550282(12721019, +), ADediting_1550283(12721023, +), ADediting_1550284(12721027, +), ADediting_1550285(12721028, +), ADediting_1550286(12723553, +), ADediting_1550287(12723558, +), ADediting_1550288(12723592, +), ADediting_1550289(12723654, +), ADediting_1629044(12711152, +),

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RNA editing positional annotations for PSMG2 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_680393chr18_12659412_+intronic
ADediting_680394chr18_12659413_+intronic
ADediting_680395chr18_12659443_+intronic
ADediting_680396chr18_12659457_+intronic
ADediting_680397chr18_12659481_+intronic
ADediting_680398chr18_12659483_+intronic
ADediting_680399chr18_12659491_+intronic
ADediting_680400chr18_12659523_+intronic
ADediting_680401chr18_12659549_+intronic
ADediting_680402chr18_12659550_+intronic
ADediting_680403chr18_12659559_+intronic
ADediting_680404chr18_12659576_+intronic
ADediting_680405chr18_12659591_+intronic
ADediting_680406chr18_12659605_+intronic
ADediting_680407chr18_12659612_+intronic
ADediting_680408chr18_12659619_+intronic
ADediting_680409chr18_12659620_+intronic
ADediting_680410chr18_12659625_+intronic
ADediting_680411chr18_12659627_+intronic
ADediting_680412chr18_12660346_+intronic
ADediting_680413chr18_12660371_+intronic
ADediting_680414chr18_12660386_+intronic
ADediting_680415chr18_12660391_+intronic
ADediting_680416chr18_12660421_+intronic
ADediting_680417chr18_12660461_+intronic
ADediting_680418chr18_12660519_+intronic
ADediting_680419chr18_12660573_+intronic
ADediting_680420chr18_12660595_+intronic
ADediting_680421chr18_12661030_+intronic
ADediting_680422chr18_12661098_+intronic
ADediting_680423chr18_12661161_+intronic
ADediting_680424chr18_12661210_+intronic
ADediting_680425chr18_12661214_+intronic
ADediting_680426chr18_12661249_+intronic
ADediting_680427chr18_12661263_+intronic
ADediting_680428chr18_12661304_+intronic
ADediting_680429chr18_12661510_+intronic
ADediting_680430chr18_12661534_+intronic
ADediting_680431chr18_12661547_+intronic
ADediting_680432chr18_12661585_+intronic
ADediting_680433chr18_12661586_+intronic
ADediting_680434chr18_12661596_+intronic
ADediting_680435chr18_12661607_+intronic
ADediting_680436chr18_12661628_+intronic
ADediting_680437chr18_12661646_+intronic
ADediting_680438chr18_12661654_+intronic
ADediting_680439chr18_12661655_+intronic
ADediting_680440chr18_12708458_+intronic
ADediting_680441chr18_12709252_+intronic
ADediting_680442chr18_12710845_+intronic
ADediting_680443chr18_12711025_+intronic
ADediting_680444chr18_12713829_+intronic
ADediting_680445chr18_12715635_+intronic
ADediting_680446chr18_12720904_+intronic
ADediting_680447chr18_12720910_+intronic
ADediting_680448chr18_12720911_+intronic
ADediting_680449chr18_12721000_+intronic
ADediting_680450chr18_12721001_+intronic
ADediting_680451chr18_12721003_+intronic
ADediting_680452chr18_12721004_+intronic
ADediting_680453chr18_12721014_+intronic
ADediting_680454chr18_12721017_+intronic
ADediting_680455chr18_12721018_+intronic
ADediting_680456chr18_12721020_+intronic
ADediting_680457chr18_12721021_+intronic
ADediting_680458chr18_12721025_+intronic
ADediting_680459chr18_12721026_+intronic
ADediting_680460chr18_12721029_+intronic
ADediting_680461chr18_12721030_+intronic
ADediting_680462chr18_12721033_+intronic
ADediting_680463chr18_12721059_+intronic
ADediting_680464chr18_12721069_+intronic
ADediting_680465chr18_12721187_+intronic
ADediting_680466chr18_12721190_+intronic
ADediting_680467chr18_12723479_+intronic
ADediting_680468chr18_12723515_+intronic
ADediting_680469chr18_12723531_+intronic
ADediting_680470chr18_12723533_+intronic
ADediting_680471chr18_12723557_+intronic
ADediting_680472chr18_12723564_+intronic
ADediting_680473chr18_12723572_+intronic
ADediting_680474chr18_12723575_+intronic
ADediting_680475chr18_12723579_+intronic
ADediting_680476chr18_12723589_+intronic
ADediting_680477chr18_12723666_+intronic
ADediting_1550271chr18_12659452_+intronic
ADediting_1550272chr18_12659502_+intronic
ADediting_1550273chr18_12659590_+intronic
ADediting_1550274chr18_12661291_+intronic
ADediting_1550275chr18_12713860_+intronic
ADediting_1550276chr18_12713891_+intronic
ADediting_1550277chr18_12713916_+intronic
ADediting_1550278chr18_12715623_+intronic
ADediting_1550279chr18_12715758_+intronic
ADediting_1550280chr18_12715768_+intronic
ADediting_1550281chr18_12721002_+intronic
ADediting_1550282chr18_12721019_+intronic
ADediting_1550283chr18_12721023_+intronic
ADediting_1550284chr18_12721027_+intronic
ADediting_1550285chr18_12721028_+intronic
ADediting_1550286chr18_12723553_+intronic
ADediting_1550287chr18_12723558_+intronic
ADediting_1550288chr18_12723592_+intronic
ADediting_1550289chr18_12723654_+intronic
ADediting_1629044chr18_12711152_+intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_680393chr18_12659412_+SINEAluName=AluSx
ADediting_680394chr18_12659413_+SINEAluName=AluSx
ADediting_680395chr18_12659443_+SINEAluName=AluSx
ADediting_680396chr18_12659457_+SINEAluName=AluSx
ADediting_680397chr18_12659481_+SINEAluName=AluSx
ADediting_680398chr18_12659483_+SINEAluName=AluSx
ADediting_680399chr18_12659491_+SINEAluName=AluSx
ADediting_680400chr18_12659523_+SINEAluName=AluSx
ADediting_680401chr18_12659549_+SINEAluName=AluSx
ADediting_680402chr18_12659550_+SINEAluName=AluSx
ADediting_680403chr18_12659559_+SINEAluName=AluSx
ADediting_680404chr18_12659576_+SINEAluName=AluSx
ADediting_680405chr18_12659591_+SINEAluName=AluSx
ADediting_680406chr18_12659605_+SINEAluName=AluSx
ADediting_680407chr18_12659612_+SINEAluName=AluSx
ADediting_680408chr18_12659619_+SINEAluName=AluSx
ADediting_680409chr18_12659620_+SINEAluName=AluSx
ADediting_680410chr18_12659625_+SINEAluName=AluSx
ADediting_680411chr18_12659627_+SINEAluName=AluSx
ADediting_680412chr18_12660346_+SINEAluName=AluSz6
ADediting_680413chr18_12660371_+SINEAluName=AluSz6
ADediting_680414chr18_12660386_+SINEAluName=AluSz6
ADediting_680415chr18_12660391_+SINEAluName=AluSz6
ADediting_680416chr18_12660421_+SINEAluName=AluSz6
ADediting_680417chr18_12660461_+SINEAluName=AluSz6
ADediting_680418chr18_12660519_+SINEAluName=AluSz6
ADediting_680419chr18_12660573_+SINEAluName=AluSz6
ADediting_680420chr18_12660595_+SINEAluName=AluSz6
ADediting_680421chr18_12661030_+SINEAluName=AluSq2
ADediting_680422chr18_12661098_+SINEAluName=AluSq2
ADediting_680423chr18_12661161_+SINEAluName=AluSq2
ADediting_680424chr18_12661210_+SINEAluName=AluSq2
ADediting_680425chr18_12661214_+SINEAluName=AluSq2
ADediting_680426chr18_12661249_+SINEAluName=AluSq2
ADediting_680427chr18_12661263_+SINEAluName=AluSq2
ADediting_680428chr18_12661304_+SINEAluName=AluSq2
ADediting_680429chr18_12661510_+SINEAluName=AluSz
ADediting_680430chr18_12661534_+SINEAluName=AluSz
ADediting_680431chr18_12661547_+SINEAluName=AluSz
ADediting_680432chr18_12661585_+SINEAluName=AluSz
ADediting_680433chr18_12661586_+SINEAluName=AluSz
ADediting_680434chr18_12661596_+SINEAluName=AluSz
ADediting_680435chr18_12661607_+SINEAluName=AluSz
ADediting_680436chr18_12661628_+SINEAluName=AluSz
ADediting_680437chr18_12661646_+SINEAluName=AluSz
ADediting_680438chr18_12661654_+SINEAluName=AluSz
ADediting_680439chr18_12661655_+SINEAluName=AluSz
ADediting_680440chr18_12708458_+SINEAluName=AluSp
ADediting_680441chr18_12709252_+SINEAluName=AluSc8
ADediting_680442chr18_12710845_+SINEAluName=AluSx
ADediting_680443chr18_12711025_+SINEAluName=AluSx
ADediting_680444chr18_12713829_+SINEAluName=AluSz6
ADediting_680445chr18_12715635_+SINEAluName=AluSx1
ADediting_680446chr18_12720904_+SINEAluName=AluY
ADediting_680447chr18_12720910_+SINEAluName=AluY
ADediting_680448chr18_12720911_+SINEAluName=AluY
ADediting_680449chr18_12721000_+SINEAluName=AluY
ADediting_680450chr18_12721001_+SINEAluName=AluY
ADediting_680451chr18_12721003_+SINEAluName=AluY
ADediting_680452chr18_12721004_+SINEAluName=AluY
ADediting_680453chr18_12721014_+SINEAluName=AluY
ADediting_680454chr18_12721017_+SINEAluName=AluY
ADediting_680455chr18_12721018_+SINEAluName=AluY
ADediting_680456chr18_12721020_+SINEAluName=AluY
ADediting_680457chr18_12721021_+SINEAluName=AluY
ADediting_680458chr18_12721025_+SINEAluName=AluY
ADediting_680459chr18_12721026_+SINEAluName=AluY
ADediting_680460chr18_12721029_+SINEAluName=AluY
ADediting_680461chr18_12721030_+SINEAluName=AluY
ADediting_680462chr18_12721033_+SINEAluName=AluY
ADediting_680463chr18_12721059_+SINEAluName=AluY
ADediting_680464chr18_12721069_+SINEAluName=AluY
ADediting_680465chr18_12721187_+SINEAluName=AluY
ADediting_680466chr18_12721190_+SINEAluName=AluY
ADediting_680468chr18_12723515_+SINEAluName=AluSz
ADediting_680469chr18_12723531_+SINEAluName=AluSz
ADediting_680470chr18_12723533_+SINEAluName=AluSz
ADediting_680471chr18_12723557_+SINEAluName=AluSz
ADediting_680472chr18_12723564_+SINEAluName=AluSz
ADediting_680473chr18_12723572_+SINEAluName=AluSz
ADediting_680474chr18_12723575_+SINEAluName=AluSz
ADediting_680475chr18_12723579_+SINEAluName=AluSz
ADediting_680476chr18_12723589_+SINEAluName=AluSz
ADediting_680477chr18_12723666_+SINEAluName=AluSz
ADediting_1550271chr18_12659452_+SINEAluName=AluSx
ADediting_1550272chr18_12659502_+SINEAluName=AluSx
ADediting_1550273chr18_12659590_+SINEAluName=AluSx
ADediting_1550274chr18_12661291_+SINEAluName=AluSq2
ADediting_1550275chr18_12713860_+SINEAluName=AluSz6
ADediting_1550276chr18_12713891_+SINEAluName=AluSz6
ADediting_1550277chr18_12713916_+SINEAluName=AluSz6
ADediting_1550278chr18_12715623_+SINEAluName=AluSx1
ADediting_1550279chr18_12715758_+SINEAluName=AluSx1
ADediting_1550280chr18_12715768_+SINEAluName=AluSx1
ADediting_1550281chr18_12721002_+SINEAluName=AluY
ADediting_1550282chr18_12721019_+SINEAluName=AluY
ADediting_1550283chr18_12721023_+SINEAluName=AluY
ADediting_1550284chr18_12721027_+SINEAluName=AluY
ADediting_1550285chr18_12721028_+SINEAluName=AluY
ADediting_1550286chr18_12723553_+SINEAluName=AluSz
ADediting_1550287chr18_12723558_+SINEAluName=AluSz
ADediting_1550288chr18_12723592_+SINEAluName=AluSz
ADediting_1550289chr18_12723654_+SINEAluName=AluSz
ADediting_1629044chr18_12711152_+SINEAluName=AluSz6

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RNA A-to-I editing events in the alternative splicing sites for PSMG2

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for PSMG2

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for PSMG2

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for PSMG2


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_843620chr2_207754818_+ENSG00000128789.21ENST00000590217.5PSMG2-210hsa-miR-4775chr1812724769127247757mer-m81272475312724776145-9.6

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for PSMG2

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for PSMG2

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_680410chr18_12659625_+0.08986124262963440.0964986107261120.6868138375159890.02298908124313851.69394948506663e-090.333673182216245
DLPFCADediting_680417chr18_12660461_+0.03636214038200260.1189244345661140.3600347839789580.05216079874468075.88871869499893e-110.360685256821739
DLPFCADediting_680421chr18_12661030_+0.2457513508492440.06612002898083770.988821887063289-0.0007989502234620321.57365135611058e-090.334294183457947
DLPFCADediting_680435chr18_12661607_+0.880611790792070.008564872885567610.20992899952065-0.07140635601473547.94258863686261e-090.320315114374061
CERADediting_680444chr18_12713829_+0.008781062644409420.2132764478562510.0001194397490293510.3089909835648960.04638178688588350.162912766864894
CERADediting_680447chr18_12720910_+0.0001442100301661340.3054421063088520.0004757767105969170.2818388519312050.549424503000152-0.0492597342821931
CERADediting_680448chr18_12720911_+1.39471711248803e-060.3821579214462424.52807838168819e-070.3981185026852280.651410624360674-0.0371879217966731
DLPFCADediting_680449chr18_12721000_+0.09825193511346120.09407779930875610.8696231827924930.00935997107094762.87851022308788e-110.366124597305615
CERADediting_680449chr18_12721000_+8.21627850669714e-050.3159056917215051.91213565021484e-050.3413576600691110.3164304552880180.0823481306674224
CERADediting_680450chr18_12721001_+2.61690320666583e-050.3360664350676293.23718943710526e-060.3696352744479360.3819671438428230.0718934521451063
CERADediting_680451chr18_12721003_+2.24426150939671e-050.3386689308440269.28917283486461e-070.3880213440113340.09317214627830550.137579616651308
CERADediting_680455chr18_12721018_+2.04912748405085e-050.3401990722264481.61475048458944e-050.3441689081152950.7513139406531960.0260892158707343
DLPFCADediting_680462chr18_12721033_+0.07200679119771270.1023256089348150.7653162073553530.0170215950461814.96513968398908e-080.303571985147262
CERADediting_680462chr18_12721033_+2.09872536420382e-050.3397975418838981.72865529264593e-060.3790146888416510.912258716190399-0.00907268571341658
CERADediting_680464chr18_12721069_+0.0005171274574803240.2801119115986421.61770161105307e-060.3799895923148680.4321476142315960.0646110446010052
CERADediting_680467chr18_12723479_+2.35585820044642e-080.4364766117914251.08275643544193e-100.4960555431204770.6346363324947370.0391131914567588
CERADediting_680468chr18_12723515_+5.16527269445839e-060.3624536598901160.0001336001650186840.306886595085190.1402169605941060.121001172681951
CERADediting_680471chr18_12723557_+1.68364705833812e-050.3434765622543522.30238486379874e-070.4073267989915620.5462803634995180.0496477023791296
DLPFCADediting_680472chr18_12723564_+1.46167678001877e-060.2695620434052280.002796983732354980.169233236476041.24311745910723e-140.419328181636115
CERADediting_680472chr18_12723564_+1.19594039608822e-070.4159884870144791.10999812601322e-080.4455261012778140.3338155752691770.0794506947947099
CERADediting_680473chr18_12723572_+4.15825807730496e-080.4294645160520341.94322895712175e-080.4388173684512070.516343644248320.053398843428037
CERADediting_680474chr18_12723575_+8.33870655916808e-050.3156355068470020.0001480787898019280.304939947651160.06655723793912680.150204236764948
CERADediting_680475chr18_12723579_+0.0005064421983013470.2805456014326873.34744568933063e-050.3318459202475810.02745973026639210.180063107726709
CERADediting_680476chr18_12723589_+6.66613274768846e-070.3927256319671725.05748519626073e-070.3965863667123220.01343732957506420.201446564351215
CERADediting_680477chr18_12723666_+9.32457344065188e-100.47357511831437.02250863375488e-110.5003855992391050.1360167509185640.122288129781709

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC2.89355044274762e-420.6731508051311133.89878275508507e-450.6899448963097483.68705680764695e-080.306362733107707
AC1.41803792559349e-630.8256038330192811.28355326935734e-400.7161946514867687.79499261211773e-200.53403527329865
PCC4.79443208235876e-180.5728021750755436.51298308670874e-190.5848133312846530.006864492847251280.19500595119424
CER1.58610445291346e-090.4677691063455611.47571196945759e-080.4421325348715760.1222434605749010.126734272834772
TCX1.40435867755399e-220.690597398772523.53004612747476e-120.5287369859448510.02958929082877140.177702817456392
FP1.35041817037159e-170.5830601755537169.64169685752546e-280.7020100764525880.5471307038743270.0454234171641641
IFG0.0008031401602704610.626644805429090.0119252854289240.4947632937443690.85042040708067-0.0397359270529068
PG1.19173567699238e-530.8521946910820642.7653988212489e-290.7051680518811650.712757116495141-0.0271726815588735
STG5.31336961187573e-180.7747453919676248.70983920764777e-160.7401142289801910.695231790428916-0.0433748720976608

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Relation with AD stages for PSMG2

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
CERADediting_1550285chr18_12721028_+0.001349196188890420.304610806344752

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
IFG0.0411308732744888-0.411223450149529

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RelatedDrugs for PSMG2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for PSMG2

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource