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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

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Differntial gene expression between RNA A-to-I edited versus non-edited samples

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Protein coding region RNA A-to-I editings

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The effects of the RNA editing to the miRNA binding sites

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The effects of the RNA editing to the stability of the RNA structures

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Relation with ADAR

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Relation with AD stages

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Related drugs with this gene

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Related diseases with this gene


Gene summary for AKIP1

check button Gene summary
Gene informationGene symbol

AKIP1

Gene ID

56672

Gene nameA-kinase interacting protein 1
SynonymsBCA3|C11orf17
Cytomap

11p15.4

Type of geneprotein-coding
DescriptionA-kinase-interacting protein 1A kinase (PRKA) interacting protein 1breast cancer associated gene 3koyt binding protein 1koyt binding protein 2koyt binding protein 3proline-rich protein BCA3
Modification date20200313
UniProtAcc

Q9NQ31,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for AKIP1

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_289848(8911942, +), ADediting_289849(8911943, +), ADediting_289850(8911999, +), ADediting_289851(8912033, +), ADediting_289852(8912037, +), ADediting_289853(8912050, +), ADediting_289854(8912076, +), ADediting_289855(8912077, +), ADediting_289856(8912089, +), ADediting_289857(8912142, +), ADediting_289858(8912188, +), ADediting_289859(8913001, +), ADediting_289860(8913014, +), ADediting_289861(8913244, +), ADediting_289862(8913327, +), ADediting_289863(8913362, +), ADediting_289864(8913368, +), ADediting_289865(8913371, +), ADediting_289866(8913377, +), ADediting_289867(8913397, +), ADediting_289868(8913450, +), ADediting_289869(8913462, +), ADediting_289871(8919687, +), ADediting_289872(8919754, +), ADediting_289873(8919802, +), ADediting_289874(8919819, +), ADediting_289875(8919822, +), ADediting_289876(8919836, +), ADediting_289877(8919839, +), ADediting_289878(8919884, +), ADediting_289879(8919898, +), ADediting_289880(8919899, +), ADediting_289881(8919911, +), ADediting_289882(8919913, +), ADediting_1529197(8912014, +), ADediting_1529198(8912040, +), ADediting_1611249(8912149, +), ADediting_1611250(8919782, +),

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RNA editing positional annotations for AKIP1 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_289848chr11_8911942_+intronic
ADediting_289849chr11_8911943_+intronic
ADediting_289850chr11_8911999_+intronic
ADediting_289851chr11_8912033_+intronic
ADediting_289852chr11_8912037_+intronic
ADediting_289853chr11_8912050_+intronic
ADediting_289854chr11_8912076_+intronic
ADediting_289855chr11_8912077_+intronic
ADediting_289856chr11_8912089_+intronic
ADediting_289857chr11_8912142_+intronic
ADediting_289858chr11_8912188_+intronic
ADediting_289859chr11_8913001_+intronic
ADediting_289860chr11_8913014_+intronic
ADediting_289861chr11_8913244_+intronic
ADediting_289862chr11_8913327_+intronic
ADediting_289863chr11_8913362_+intronic
ADediting_289864chr11_8913368_+intronic
ADediting_289865chr11_8913371_+intronic
ADediting_289866chr11_8913377_+intronic
ADediting_289867chr11_8913397_+intronic
ADediting_289868chr11_8913450_+intronic
ADediting_289869chr11_8913462_+intronic
ADediting_289871chr11_8919687_+UTR3
ADediting_289872chr11_8919754_+UTR3
ADediting_289873chr11_8919802_+UTR3
ADediting_289874chr11_8919819_+UTR3
ADediting_289875chr11_8919822_+UTR3
ADediting_289876chr11_8919836_+UTR3
ADediting_289877chr11_8919839_+UTR3
ADediting_289878chr11_8919884_+UTR3
ADediting_289879chr11_8919898_+UTR3
ADediting_289880chr11_8919899_+UTR3
ADediting_289881chr11_8919911_+UTR3
ADediting_289882chr11_8919913_+UTR3
ADediting_1529197chr11_8912014_+intronic
ADediting_1529198chr11_8912040_+intronic
ADediting_1611249chr11_8912149_+intronic
ADediting_1611250chr11_8919782_+UTR3

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_289848chr11_8911942_+SINEAluName=AluSp
ADediting_289849chr11_8911943_+SINEAluName=AluSp
ADediting_289850chr11_8911999_+SINEAluName=AluSp
ADediting_289851chr11_8912033_+SINEAluName=AluSp
ADediting_289852chr11_8912037_+SINEAluName=AluSp
ADediting_289853chr11_8912050_+SINEAluName=AluSp
ADediting_289854chr11_8912076_+SINEAluName=AluSp
ADediting_289855chr11_8912077_+SINEAluName=AluSp
ADediting_289856chr11_8912089_+SINEAluName=AluSp
ADediting_289857chr11_8912142_+SINEAluName=AluSp
ADediting_289858chr11_8912188_+SINEAluName=AluSp
ADediting_289859chr11_8913001_+SINEAluName=AluY
ADediting_289860chr11_8913014_+SINEAluName=AluY
ADediting_289861chr11_8913244_+SINEAluName=AluSz
ADediting_289862chr11_8913327_+SINEAluName=AluSz
ADediting_289863chr11_8913362_+SINEAluName=AluSz
ADediting_289864chr11_8913368_+SINEAluName=AluSz
ADediting_289865chr11_8913371_+SINEAluName=AluSz
ADediting_289866chr11_8913377_+SINEAluName=AluSz
ADediting_289867chr11_8913397_+SINEAluName=AluSz
ADediting_289868chr11_8913450_+SINEAluName=AluSz
ADediting_289869chr11_8913462_+SINEAluName=AluSz
ADediting_289871chr11_8919687_+SINEAluName=AluY
ADediting_289872chr11_8919754_+SINEAluName=AluY
ADediting_289873chr11_8919802_+SINEAluName=AluY
ADediting_289874chr11_8919819_+SINEAluName=AluY
ADediting_289875chr11_8919822_+SINEAluName=AluY
ADediting_289876chr11_8919836_+SINEAluName=AluY
ADediting_289877chr11_8919839_+SINEAluName=AluY
ADediting_289878chr11_8919884_+SINEAluName=AluY
ADediting_289879chr11_8919898_+SINEAluName=AluY
ADediting_289880chr11_8919899_+SINEAluName=AluY
ADediting_289881chr11_8919911_+SINEAluName=AluY
ADediting_289882chr11_8919913_+SINEAluName=AluY
ADediting_1529197chr11_8912014_+SINEAluName=AluSp
ADediting_1529198chr11_8912040_+SINEAluName=AluSp
ADediting_1611249chr11_8912149_+SINEAluName=AluSp
ADediting_1611250chr11_8919782_+SINEAluName=AluY

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RNA A-to-I editing events in the alternative splicing sites for AKIP1

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for AKIP1

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
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boxplot
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for AKIP1

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for AKIP1

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-4767chr11891978089197867mer-m889197668919787155-27.47
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-6499-5pchr11891977989197857mer-m889197648919786141-21.9
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-6720-3pchr11891977689197827mer-m889197628919783152-19.58
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-9899chr11891977889197847mer-m889197638919785146-26.17
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-4767chr11891978089197867mer-m889197668919787155-27.47
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-6499-5pchr11891977989197857mer-m889197648919786141-21.9
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-6720-3pchr11891977689197827mer-m889197628919783152-19.58
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-9899chr11891977889197847mer-m889197638919785146-26.17
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-4767chr11891978089197867mer-m889197668919787155-27.47
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-6499-5pchr11891977989197857mer-m889197648919786141-21.9
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-6720-3pchr11891977689197827mer-m889197628919783152-19.58
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-9899chr11891977889197847mer-m889197638919785146-26.17
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-4767chr11891978089197867mer-m889197668919787155-27.47
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-6499-5pchr11891977989197857mer-m889197648919786141-21.9
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-6720-3pchr11891977689197827mer-m889197628919783152-19.58
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-9899chr11891977889197847mer-m889197638919785146-26.17
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000534147.5AKIP1-210hsa-miR-4767chr11891978089197867mer-m889197668919787155-27.47
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000534147.5AKIP1-210hsa-miR-6499-5pchr11891977989197857mer-m889197648919786141-21.9
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000534147.5AKIP1-210hsa-miR-6720-3pchr11891977689197827mer-m889197628919783152-19.58
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000534147.5AKIP1-210hsa-miR-9899chr11891977889197847mer-m889197638919785146-26.17
ADediting_289872chr11_8919754_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-6089chr11891975289197587mer-m889197368919759165-39.43
ADediting_289872chr11_8919754_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-6089chr11891975289197587mer-m889197368919759165-39.43
ADediting_289872chr11_8919754_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-6089chr11891975289197587mer-m889197368919759165-39.43
ADediting_289872chr11_8919754_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-6089chr11891975289197587mer-m889197368919759165-39.43
ADediting_289872chr11_8919754_+ENSG00000166452.12ENST00000534147.5AKIP1-210hsa-miR-6089chr11891975289197587mer-m889197368919759165-39.43
ADediting_289877chr11_8919839_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-433-5pchr11891983389198397mer-m889198178919840163-28.05
ADediting_289877chr11_8919839_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-433-5pchr11891983389198397mer-m889198178919840163-28.05
ADediting_289877chr11_8919839_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-433-5pchr11891983389198397mer-m889198178919840163-28.05
ADediting_289877chr11_8919839_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-433-5pchr11891983389198397mer-m889198178919840163-28.05
ADediting_289877chr11_8919839_+ENSG00000166452.12ENST00000534147.5AKIP1-210hsa-miR-433-5pchr11891983389198397mer-m889198178919840163-28.05
ADediting_289879chr11_8919898_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-3192-5pchr11891989189198988mer-1a89198798919898156-25.88
ADediting_289879chr11_8919898_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-326chr11891989389198997mer-m889198818919900140-14.14
ADediting_289879chr11_8919898_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-330-5pchr11891989389198997mer-m889198798919900140-21.34
ADediting_289879chr11_8919898_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-4314chr11891989289198987mer-m889198828919899140-18.8
ADediting_289879chr11_8919898_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-514a-5pchr11891989489199007mer-m889198818919901154-19.44
ADediting_289879chr11_8919898_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-3192-5pchr11891989189198988mer-1a89198798919898156-25.88
ADediting_289879chr11_8919898_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-326chr11891989389198997mer-m889198818919900140-14.14
ADediting_289879chr11_8919898_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-330-5pchr11891989389198997mer-m889198798919900140-21.34
ADediting_289879chr11_8919898_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-4314chr11891989289198987mer-m889198828919899140-18.8
ADediting_289879chr11_8919898_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-514a-5pchr11891989489199007mer-m889198818919901154-19.44
ADediting_289879chr11_8919898_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-3192-5pchr11891989189198988mer-1a89198798919898156-25.88
ADediting_289879chr11_8919898_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-326chr11891989389198997mer-m889198818919900140-14.14
ADediting_289879chr11_8919898_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-330-5pchr11891989389198997mer-m889198798919900140-21.34
ADediting_289879chr11_8919898_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-4314chr11891989289198987mer-m889198828919899140-18.8
ADediting_289879chr11_8919898_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-514a-5pchr11891989489199007mer-m889198818919901154-19.44
ADediting_289879chr11_8919898_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-3192-5pchr11891989189198988mer-1a89198798919898156-25.88
ADediting_289879chr11_8919898_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-326chr11891989389198997mer-m889198818919899140-14.1
ADediting_289879chr11_8919898_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-330-5pchr11891989389198997mer-m889198798919899140-20.09
ADediting_289879chr11_8919898_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-4314chr11891989289198987mer-m889198828919899140-18.8
ADediting_289880chr11_8919899_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-3189-3pchr11891989389198997mer-m889198778919900149-20.43
ADediting_289880chr11_8919899_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-6813-3pchr11891989489199007mer-m889198818919901140-16.1
ADediting_289880chr11_8919899_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-3189-3pchr11891989389198997mer-m889198778919900149-20.43
ADediting_289880chr11_8919899_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-6813-3pchr11891989489199007mer-m889198818919901140-16.1
ADediting_289880chr11_8919899_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-3189-3pchr11891989389198997mer-m889198778919900149-20.43
ADediting_289880chr11_8919899_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-6813-3pchr11891989489199007mer-m889198818919901140-16.1
ADediting_289880chr11_8919899_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-3189-3pchr11891989389198997mer-m889198778919899149-20.39

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-550a-3-5pchr11891977689197827mer-m889197658919783144-15.9
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-550a-5pchr11891977689197827mer-m889197628919783144-18.24
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-6514-3pchr11891977589197817mer-m889197618919782154-15.57
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-550a-3-5pchr11891977689197827mer-m889197658919783144-15.9
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-550a-5pchr11891977689197827mer-m889197628919783144-18.24
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-6514-3pchr11891977589197817mer-m889197618919782154-15.57
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-550a-3-5pchr11891977689197827mer-m889197658919783144-15.9
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-550a-5pchr11891977689197827mer-m889197628919783144-18.24
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-6514-3pchr11891977589197817mer-m889197618919782154-15.57
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-550a-3-5pchr11891977689197827mer-m889197658919783144-15.9
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-550a-5pchr11891977689197827mer-m889197628919783144-18.24
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-6514-3pchr11891977589197817mer-m889197618919782154-15.57
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000534147.5AKIP1-210hsa-miR-550a-3-5pchr11891977689197827mer-m889197658919783144-15.9
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000534147.5AKIP1-210hsa-miR-550a-5pchr11891977689197827mer-m889197628919783144-18.24
ADediting_1611250chr11_8919782_+ENSG00000166452.12ENST00000534147.5AKIP1-210hsa-miR-6514-3pchr11891977589197817mer-m889197618919782154-15.57
ADediting_289871chr11_8919687_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-508-5pchr11891968289196887mer-m889196658919689152-24.47
ADediting_289871chr11_8919687_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-6512-3pchr11891968089196867mer-m889196668919687146-18.8
ADediting_289871chr11_8919687_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-6720-5pchr11891968089196867mer-m889196658919687151-22.61
ADediting_289871chr11_8919687_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-766-3pchr11891968189196877mer-m889196638919688147-23
ADediting_289871chr11_8919687_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-508-5pchr11891968289196887mer-m889196658919689152-24.47
ADediting_289871chr11_8919687_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-6512-3pchr11891968089196867mer-m889196668919687146-18.8
ADediting_289871chr11_8919687_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-6720-5pchr11891968089196867mer-m889196658919687151-22.61
ADediting_289871chr11_8919687_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-766-3pchr11891968189196877mer-m889196638919688147-23
ADediting_289871chr11_8919687_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-508-5pchr11891968289196887mer-m889196658919689152-24.47
ADediting_289871chr11_8919687_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-6512-3pchr11891968089196867mer-m889196668919687146-18.8
ADediting_289871chr11_8919687_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-6720-5pchr11891968089196867mer-m889196658919687151-22.61
ADediting_289871chr11_8919687_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-766-3pchr11891968189196877mer-m889196638919688147-23
ADediting_289871chr11_8919687_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-508-5pchr11891968289196887mer-m889196658919689152-24.47
ADediting_289871chr11_8919687_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-6512-3pchr11891968089196867mer-m889196668919687146-18.8
ADediting_289871chr11_8919687_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-6720-5pchr11891968089196867mer-m889196658919687151-22.61
ADediting_289871chr11_8919687_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-766-3pchr11891968189196877mer-m889196638919688147-23
ADediting_289871chr11_8919687_+ENSG00000166452.12ENST00000534147.5AKIP1-210hsa-miR-508-5pchr11891968289196887mer-m889196658919689152-24.47
ADediting_289871chr11_8919687_+ENSG00000166452.12ENST00000534147.5AKIP1-210hsa-miR-6512-3pchr11891968089196867mer-m889196668919687146-18.8
ADediting_289871chr11_8919687_+ENSG00000166452.12ENST00000534147.5AKIP1-210hsa-miR-6720-5pchr11891968089196867mer-m889196658919687151-22.61
ADediting_289871chr11_8919687_+ENSG00000166452.12ENST00000534147.5AKIP1-210hsa-miR-766-3pchr11891968189196877mer-m889196638919688147-23
ADediting_289872chr11_8919754_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-4478chr11891975189197577mer-m889197438919758149-25.05
ADediting_289872chr11_8919754_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-4649-3pchr11891974889197547mer-m889197358919755140-14.11
ADediting_289872chr11_8919754_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-7160-5pchr11891974989197557mer-m889197378919756149-18.69
ADediting_289872chr11_8919754_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-4478chr11891975189197577mer-m889197438919758149-25.05
ADediting_289872chr11_8919754_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-4649-3pchr11891974889197547mer-m889197358919755140-14.11
ADediting_289872chr11_8919754_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-7160-5pchr11891974989197557mer-m889197378919756149-18.69
ADediting_289872chr11_8919754_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-4478chr11891975189197577mer-m889197438919758149-25.05
ADediting_289872chr11_8919754_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-4649-3pchr11891974889197547mer-m889197358919755140-14.11
ADediting_289872chr11_8919754_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-7160-5pchr11891974989197557mer-m889197378919756149-18.69
ADediting_289872chr11_8919754_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-4478chr11891975189197577mer-m889197438919758149-25.05
ADediting_289872chr11_8919754_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-4649-3pchr11891974889197547mer-m889197358919755140-14.11
ADediting_289872chr11_8919754_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-7160-5pchr11891974989197557mer-m889197378919756149-18.69
ADediting_289872chr11_8919754_+ENSG00000166452.12ENST00000534147.5AKIP1-210hsa-miR-4478chr11891975189197577mer-m889197438919758149-25.05
ADediting_289872chr11_8919754_+ENSG00000166452.12ENST00000534147.5AKIP1-210hsa-miR-4649-3pchr11891974889197547mer-m889197358919755140-14.11
ADediting_289872chr11_8919754_+ENSG00000166452.12ENST00000534147.5AKIP1-210hsa-miR-7160-5pchr11891974989197557mer-m889197378919756149-18.69
ADediting_289878chr11_8919884_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-4761-5pchr11891988289198887mer-m889198688919889148-14.15
ADediting_289878chr11_8919884_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-6748-5pchr11891987889198847mer-m889198608919885150-20.38
ADediting_289878chr11_8919884_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-6769a-5pchr11891987989198857mer-m889198648919886142-20.99
ADediting_289878chr11_8919884_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-6769b-5pchr11891987989198857mer-m889198608919886159-30.18
ADediting_289878chr11_8919884_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-4761-5pchr11891988289198887mer-m889198688919889148-14.15
ADediting_289878chr11_8919884_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-6748-5pchr11891987889198847mer-m889198608919885150-20.38
ADediting_289878chr11_8919884_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-6769a-5pchr11891987989198857mer-m889198648919886142-20.99
ADediting_289878chr11_8919884_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-6769b-5pchr11891987989198857mer-m889198608919886159-30.18
ADediting_289878chr11_8919884_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-4761-5pchr11891988289198887mer-m889198688919889148-14.15
ADediting_289878chr11_8919884_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-6748-5pchr11891987889198847mer-m889198608919885150-20.38
ADediting_289878chr11_8919884_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-6769a-5pchr11891987989198857mer-m889198648919886142-20.99
ADediting_289878chr11_8919884_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-6769b-5pchr11891987989198857mer-m889198608919886159-30.18
ADediting_289878chr11_8919884_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-4761-5pchr11891988289198887mer-m889198688919889148-14.15
ADediting_289878chr11_8919884_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-6748-5pchr11891987889198847mer-m889198608919885150-20.38
ADediting_289878chr11_8919884_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-6769a-5pchr11891987989198857mer-m889198648919886142-20.99
ADediting_289878chr11_8919884_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-6769b-5pchr11891987989198857mer-m889198608919886159-30.18
ADediting_289879chr11_8919898_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-887-5pchr11891989189198988mer-1a89198788919898147-14
ADediting_289879chr11_8919898_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-887-5pchr11891989189198988mer-1a89198788919898147-14
ADediting_289879chr11_8919898_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-887-5pchr11891989189198988mer-1a89198788919898147-14
ADediting_289879chr11_8919898_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-887-5pchr11891989189198988mer-1a89198788919898147-14

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1097295chr3_85385762_+ENSG00000166452.12ENST00000299576.9AKIP1-201hsa-miR-5688chr11891963389196397mer-m889196228919640148-9.66
ADediting_1097295chr3_85385762_+ENSG00000166452.12ENST00000309357.8AKIP1-202hsa-miR-5688chr11891963389196397mer-m889196228919640148-9.66
ADediting_1097295chr3_85385762_+ENSG00000166452.12ENST00000309377.9AKIP1-203hsa-miR-5688chr11891963389196397mer-m889196228919640148-9.66
ADediting_1097295chr3_85385762_+ENSG00000166452.12ENST00000396648.6AKIP1-204hsa-miR-5688chr11891963389196397mer-m889196228919640148-9.66
ADediting_1097295chr3_85385762_+ENSG00000166452.12ENST00000534147.5AKIP1-210hsa-miR-5688chr11891963389196397mer-m889196228919640148-9.66
ADediting_843620chr2_207754818_+ENSG00000166452.12ENST00000525005.5AKIP1-206hsa-miR-4775chr11891752689175327mer-m889175138917533146-8.6
ADediting_843620chr2_207754818_+ENSG00000166452.12ENST00000529876.5AKIP1-207hsa-miR-4775chr11891752689175327mer-m889175138917533146-8.6

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for AKIP1

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000299576.9protein_codingSoverviewSoverview
ENST00000309357.8protein_codingSoverviewSoverview
ENST00000309377.9protein_codingSoverviewSoverview
ENST00000396648.6protein_codingSoverviewSoverview
ENST00000534147.5protein_codingSoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_289871ENST00000299576.9chr11_8919687_+850-434.00-432.50-451.70
ADediting_289872ENST00000299576.9chr11_8919754_+917-433.90-432.50-451.70
ADediting_1611250ENST00000299576.9chr11_8919782_+945-432.50-432.50-451.70
ADediting_289873ENST00000299576.9chr11_8919802_+965-432.60-432.50-451.70
ADediting_289874ENST00000299576.9chr11_8919819_+982-435.70-432.50-451.70
ADediting_289875ENST00000299576.9chr11_8919822_+985-436.80-432.50-451.70
ADediting_289876ENST00000299576.9chr11_8919836_+999-433.40-432.50-451.70
ADediting_289877ENST00000299576.9chr11_8919839_+1002-434.80-432.50-451.70
ADediting_289878ENST00000299576.9chr11_8919884_+1047-431.80-432.50-451.70
ADediting_289879ENST00000299576.9chr11_8919898_+1061-432.20-432.50-451.70
ADediting_289880ENST00000299576.9chr11_8919899_+1062-437.50-432.50-451.70
ADediting_289881ENST00000299576.9chr11_8919911_+1074-432.50-432.50-451.70
ADediting_289882ENST00000299576.9chr11_8919913_+1076-436.90-432.50-451.70
ADediting_289871ENST00000309357.8chr11_8919687_+835-426.70-423.90-442.30
ADediting_289872ENST00000309357.8chr11_8919754_+902-426.00-423.90-442.30
ADediting_1611250ENST00000309357.8chr11_8919782_+930-423.90-423.90-442.30
ADediting_289873ENST00000309357.8chr11_8919802_+950-422.50-423.90-442.30
ADediting_289874ENST00000309357.8chr11_8919819_+967-427.60-423.90-442.30
ADediting_289875ENST00000309357.8chr11_8919822_+970-429.70-423.90-442.30
ADediting_289876ENST00000309357.8chr11_8919836_+984-425.80-423.90-442.30
ADediting_289877ENST00000309357.8chr11_8919839_+987-426.70-423.90-442.30
ADediting_289878ENST00000309357.8chr11_8919884_+1032-423.90-423.90-442.30
ADediting_289879ENST00000309357.8chr11_8919898_+1046-423.60-423.90-442.30
ADediting_289880ENST00000309357.8chr11_8919899_+1047-430.10-423.90-442.30
ADediting_289881ENST00000309357.8chr11_8919911_+1059-423.90-423.90-442.30
ADediting_289882ENST00000309357.8chr11_8919913_+1061-427.80-423.90-442.30
ADediting_289871ENST00000309377.9chr11_8919687_+881-433.80-431.00-448.30
ADediting_289872ENST00000309377.9chr11_8919754_+948-434.40-431.00-448.30
ADediting_1611250ENST00000309377.9chr11_8919782_+976-431.00-431.00-448.30
ADediting_289873ENST00000309377.9chr11_8919802_+996-428.50-431.00-448.30
ADediting_289874ENST00000309377.9chr11_8919819_+1013-433.20-431.00-448.30
ADediting_289875ENST00000309377.9chr11_8919822_+1016-436.50-431.00-448.30
ADediting_289876ENST00000309377.9chr11_8919836_+1030-432.60-431.00-448.30
ADediting_289877ENST00000309377.9chr11_8919839_+1033-432.60-431.00-448.30
ADediting_289878ENST00000309377.9chr11_8919884_+1078-433.00-431.00-448.30
ADediting_289879ENST00000309377.9chr11_8919898_+1092-430.70-431.00-448.30
ADediting_289880ENST00000309377.9chr11_8919899_+1093-435.80-431.00-448.30
ADediting_289881ENST00000309377.9chr11_8919911_+1105-431.00-431.00-448.30
ADediting_289882ENST00000309377.9chr11_8919913_+1107-435.50-431.00-448.30
ADediting_289871ENST00000396648.6chr11_8919687_+871-395.50-394.00-411.70
ADediting_289872ENST00000396648.6chr11_8919754_+938-399.20-394.00-411.70
ADediting_1611250ENST00000396648.6chr11_8919782_+966-394.00-394.00-411.70
ADediting_289873ENST00000396648.6chr11_8919802_+986-392.50-394.00-411.70
ADediting_289874ENST00000396648.6chr11_8919819_+1003-395.70-394.00-411.70
ADediting_289875ENST00000396648.6chr11_8919822_+1006-397.50-394.00-411.70
ADediting_289876ENST00000396648.6chr11_8919836_+1020-394.60-394.00-411.70
ADediting_289877ENST00000396648.6chr11_8919839_+1023-395.50-394.00-411.70
ADediting_289878ENST00000396648.6chr11_8919884_+1068-394.60-394.00-411.70
ADediting_289879ENST00000396648.6chr11_8919898_+1082-394.00-394.00-411.70
ADediting_289880ENST00000396648.6chr11_8919899_+1083-396.10-394.00-411.70
ADediting_289871ENST00000534147.5chr11_8919687_+847-344.70-344.00-356.60
ADediting_289872ENST00000534147.5chr11_8919754_+914-346.60-344.00-356.60
ADediting_1611250ENST00000534147.5chr11_8919782_+942-344.20-344.00-356.60
ADediting_289873ENST00000534147.5chr11_8919802_+962-342.90-344.00-356.60
ADediting_289874ENST00000534147.5chr11_8919819_+979-346.30-344.00-356.60
ADediting_289875ENST00000534147.5chr11_8919822_+982-344.20-344.00-356.60
ADediting_289876ENST00000534147.5chr11_8919836_+996-348.30-344.00-356.60
ADediting_289877ENST00000534147.5chr11_8919839_+999-344.60-344.00-356.60

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for AKIP1

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_289854chr11_8912076_+0.292792316663303-0.05993888236362730.0199881784288741-0.1320943650698712.55036812340721e-080.309779120567633
DLPFCADediting_289855chr11_8912077_+0.527573899332117-0.03601277615706460.0116074916550194-0.1431845611230616.98436781198751e-150.422932278317373
DLPFCADediting_289861chr11_8913244_+0.3688867852823440.05120818655015660.218582353601416-0.0700738688642392.51480037891143e-180.468590433784667
DLPFCADediting_289864chr11_8913368_+0.07481428368175430.1013368947647410.375063322879171-0.05055185646997582.16023212955499e-220.514946907483859
DLPFCADediting_289865chr11_8913371_+0.03848101038372760.1176175570632690.347228482304526-0.0535652564090722.71691451902123e-230.524322458601304
DLPFCADediting_289866chr11_8913377_+0.01935436280130970.1327732961225930.243752689333858-0.06640008654955251.08898669138548e-240.538316023554159

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC3.62752859237084e-190.4787724958874852.77834411691722e-090.3294656381855396.27146920272799e-450.688774159030921
AC2.11333078758952e-690.8451142725121121.77395066499226e-480.7608370962608873.68544164431403e-170.499191568048559
PCC3.95619874525592e-220.6254485486234461.24740353026271e-220.6312836903582060.003655369519079220.209343350211182
CER8.45949325944347e-150.5789583805768978.99583809445405e-090.4480071079316420.05828485000869760.154968697114197
TCX7.82810054050211e-300.7629312128309536.31776229826595e-120.5234200436293880.004185357100667930.232562384748464
FP1.30028693128604e-180.5975849441796083.0345905909515e-240.6667270638270170.01692791912109260.178822901390953
IFG5.41121563816993e-050.7175074994484370.0002043360476734250.6765941658157470.903027312199005-0.0256782903107654
PG1.28643126176189e-560.8635919854002934.11805157991562e-250.6650288017578120.8285032220653230.0159902486414491
STG9.88803278897213e-190.784968783370394.35109915566275e-130.6889436534522150.09009560411260590.186097304168051

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Relation with AD stages for AKIP1

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
TCX0.001437056457717370.305736237351274

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RelatedDrugs for AKIP1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for AKIP1

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource