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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for AZGP1 |
 Gene summary |
| Gene information | Gene symbol | AZGP1 | Gene ID | 563 |
| Gene name | alpha-2-glycoprotein 1, zinc-binding | |
| Synonyms | ZA2G|ZAG | |
| Cytomap | 7q22.1 | |
| Type of gene | protein-coding | |
| Description | zinc-alpha-2-glycoproteinAlpha-2-glycoprotein, zincZn-alpha2-glycoproteintesticular tissue protein Li 227zn-alpha-2-GPzn-alpha-2-glycoprotein | |
| Modification date | 20200313 | |
| UniProtAcc | P25311, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| AZGP1 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste | 24248522 |
| AZGP1 | GO:0007155 | cell adhesion | 9813179 |
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RNA A-to-I events for AZGP1 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_1377682(99968718, -), ADediting_1377683(99968719, -), ADediting_1377684(99968728, -), ADediting_1377685(99968737, -), ADediting_1377686(99968741, -), ADediting_1377687(99968745, -), ADediting_1377688(99968746, -), ADediting_1377689(99968778, -), ADediting_1377690(99968780, -), ADediting_1377691(99968806, -), ADediting_1377692(99968808, -), ADediting_1377693(99968831, -), ADediting_1377694(99968839, -), ADediting_1377695(99968851, -), ADediting_1377696(99968854, -), ADediting_1377697(99968863, -), ADediting_1377698(99968868, -), ADediting_1377699(99968880, -), ADediting_1377700(99968881, -), ADediting_1377701(99968887, -), ADediting_1377702(99968901, -), ADediting_1377703(99968922, -), ADediting_1377704(99968925, -), ADediting_1377705(99968929, -), ADediting_1377706(99968930, -), ADediting_1377707(99968931, -), ADediting_1377708(99968937, -), ADediting_1377709(99969082, -), ADediting_1377710(99969206, -), ADediting_1377711(99969217, -), ADediting_1377712(99969229, -), ADediting_1377713(99969243, -), ADediting_1377714(99969297, -), ADediting_1377715(99969309, -), ADediting_1377716(99969326, -), ADediting_1377717(99969327, -), ADediting_1377718(99969333, -), ADediting_1377719(99969346, -), ADediting_1377720(99969347, -), ADediting_1377721(99969349, -), ADediting_1377722(99969352, -), ADediting_1377723(99969517, -), ADediting_1377724(99970293, -), ADediting_1377725(99970309, -), ADediting_1377726(99970310, -), ADediting_1377727(99970322, -), ADediting_1377728(99970329, -), ADediting_1377729(99970333, -), ADediting_1377730(99970336, -), ADediting_1377731(99970340, -), ADediting_1377732(99970341, -), ADediting_1377733(99970349, -), ADediting_1377734(99970355, -), ADediting_1377735(99970365, -), ADediting_1377736(99970368, -), ADediting_1377737(99970372, -), ADediting_1377738(99970376, -), ADediting_1377739(99970392, -), ADediting_1377740(99970408, -), ADediting_1377741(99970411, -), ADediting_1377742(99970413, -), ADediting_1377743(99970414, -), ADediting_1377744(99970416, -), ADediting_1377745(99970470, -), ADediting_1377746(99970475, -), ADediting_1377747(99970476, -), ADediting_1377748(99970480, -), ADediting_1377749(99970485, -), ADediting_1377750(99970489, -), ADediting_1377751(99970493, -), ADediting_1377752(99970516, -), ADediting_1377753(99971443, -), ADediting_1589288(99968835, -), ADediting_1589289(99969236, -), ADediting_1589290(99969246, -), ADediting_1589291(99969523, -), ADediting_1589292(99970359, -), ADediting_1589293(99970410, -), ADediting_1589294(99970412, -), ADediting_1589295(99970418, -), ADediting_1589296(99970425, -), ADediting_1589297(99970436, -), ADediting_1589298(99970461, -), ADediting_1589299(99970524, -), |
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RNA editing positional annotations for AZGP1 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_1377682 | chr7_99968718_- | intronic |
| ADediting_1377683 | chr7_99968719_- | intronic |
| ADediting_1377684 | chr7_99968728_- | intronic |
| ADediting_1377685 | chr7_99968737_- | intronic |
| ADediting_1377686 | chr7_99968741_- | intronic |
| ADediting_1377687 | chr7_99968745_- | intronic |
| ADediting_1377688 | chr7_99968746_- | intronic |
| ADediting_1377689 | chr7_99968778_- | intronic |
| ADediting_1377690 | chr7_99968780_- | intronic |
| ADediting_1377691 | chr7_99968806_- | intronic |
| ADediting_1377692 | chr7_99968808_- | intronic |
| ADediting_1377693 | chr7_99968831_- | intronic |
| ADediting_1377694 | chr7_99968839_- | intronic |
| ADediting_1377695 | chr7_99968851_- | intronic |
| ADediting_1377696 | chr7_99968854_- | intronic |
| ADediting_1377697 | chr7_99968863_- | intronic |
| ADediting_1377698 | chr7_99968868_- | intronic |
| ADediting_1377699 | chr7_99968880_- | intronic |
| ADediting_1377700 | chr7_99968881_- | intronic |
| ADediting_1377701 | chr7_99968887_- | intronic |
| ADediting_1377702 | chr7_99968901_- | intronic |
| ADediting_1377703 | chr7_99968922_- | intronic |
| ADediting_1377704 | chr7_99968925_- | intronic |
| ADediting_1377705 | chr7_99968929_- | intronic |
| ADediting_1377706 | chr7_99968930_- | intronic |
| ADediting_1377707 | chr7_99968931_- | intronic |
| ADediting_1377708 | chr7_99968937_- | intronic |
| ADediting_1377709 | chr7_99969082_- | intronic |
| ADediting_1377710 | chr7_99969206_- | intronic |
| ADediting_1377711 | chr7_99969217_- | intronic |
| ADediting_1377712 | chr7_99969229_- | intronic |
| ADediting_1377713 | chr7_99969243_- | intronic |
| ADediting_1377714 | chr7_99969297_- | intronic |
| ADediting_1377715 | chr7_99969309_- | intronic |
| ADediting_1377716 | chr7_99969326_- | intronic |
| ADediting_1377717 | chr7_99969327_- | intronic |
| ADediting_1377718 | chr7_99969333_- | intronic |
| ADediting_1377719 | chr7_99969346_- | intronic |
| ADediting_1377720 | chr7_99969347_- | intronic |
| ADediting_1377721 | chr7_99969349_- | intronic |
| ADediting_1377722 | chr7_99969352_- | intronic |
| ADediting_1377723 | chr7_99969517_- | intronic |
| ADediting_1377724 | chr7_99970293_- | intronic |
| ADediting_1377725 | chr7_99970309_- | intronic |
| ADediting_1377726 | chr7_99970310_- | intronic |
| ADediting_1377727 | chr7_99970322_- | intronic |
| ADediting_1377728 | chr7_99970329_- | intronic |
| ADediting_1377729 | chr7_99970333_- | intronic |
| ADediting_1377730 | chr7_99970336_- | intronic |
| ADediting_1377731 | chr7_99970340_- | intronic |
| ADediting_1377732 | chr7_99970341_- | intronic |
| ADediting_1377733 | chr7_99970349_- | intronic |
| ADediting_1377734 | chr7_99970355_- | intronic |
| ADediting_1377735 | chr7_99970365_- | intronic |
| ADediting_1377736 | chr7_99970368_- | intronic |
| ADediting_1377737 | chr7_99970372_- | intronic |
| ADediting_1377738 | chr7_99970376_- | intronic |
| ADediting_1377739 | chr7_99970392_- | intronic |
| ADediting_1377740 | chr7_99970408_- | intronic |
| ADediting_1377741 | chr7_99970411_- | intronic |
| ADediting_1377742 | chr7_99970413_- | intronic |
| ADediting_1377743 | chr7_99970414_- | intronic |
| ADediting_1377744 | chr7_99970416_- | intronic |
| ADediting_1377745 | chr7_99970470_- | intronic |
| ADediting_1377746 | chr7_99970475_- | intronic |
| ADediting_1377747 | chr7_99970476_- | intronic |
| ADediting_1377748 | chr7_99970480_- | intronic |
| ADediting_1377749 | chr7_99970485_- | intronic |
| ADediting_1377750 | chr7_99970489_- | intronic |
| ADediting_1377751 | chr7_99970493_- | intronic |
| ADediting_1377752 | chr7_99970516_- | intronic |
| ADediting_1377753 | chr7_99971443_- | intronic |
| ADediting_1589288 | chr7_99968835_- | intronic |
| ADediting_1589289 | chr7_99969236_- | intronic |
| ADediting_1589290 | chr7_99969246_- | intronic |
| ADediting_1589291 | chr7_99969523_- | intronic |
| ADediting_1589292 | chr7_99970359_- | intronic |
| ADediting_1589293 | chr7_99970410_- | intronic |
| ADediting_1589294 | chr7_99970412_- | intronic |
| ADediting_1589295 | chr7_99970418_- | intronic |
| ADediting_1589296 | chr7_99970425_- | intronic |
| ADediting_1589297 | chr7_99970436_- | intronic |
| ADediting_1589298 | chr7_99970461_- | intronic |
| ADediting_1589299 | chr7_99970524_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_1377682 | chr7_99968718_- | SINE | Alu | Name=AluJb |
| ADediting_1377683 | chr7_99968719_- | SINE | Alu | Name=AluJb |
| ADediting_1377684 | chr7_99968728_- | SINE | Alu | Name=AluJb |
| ADediting_1377685 | chr7_99968737_- | SINE | Alu | Name=AluJb |
| ADediting_1377686 | chr7_99968741_- | SINE | Alu | Name=AluJb |
| ADediting_1377687 | chr7_99968745_- | SINE | Alu | Name=AluJb |
| ADediting_1377688 | chr7_99968746_- | SINE | Alu | Name=AluJb |
| ADediting_1377689 | chr7_99968778_- | SINE | Alu | Name=AluJb |
| ADediting_1377690 | chr7_99968780_- | SINE | Alu | Name=AluJb |
| ADediting_1377691 | chr7_99968806_- | SINE | Alu | Name=AluJb |
| ADediting_1377692 | chr7_99968808_- | SINE | Alu | Name=AluJb |
| ADediting_1377693 | chr7_99968831_- | SINE | Alu | Name=AluJb |
| ADediting_1377694 | chr7_99968839_- | SINE | Alu | Name=AluJb |
| ADediting_1377695 | chr7_99968851_- | SINE | Alu | Name=AluJb |
| ADediting_1377696 | chr7_99968854_- | SINE | Alu | Name=AluJb |
| ADediting_1377697 | chr7_99968863_- | SINE | Alu | Name=AluJb |
| ADediting_1377698 | chr7_99968868_- | SINE | Alu | Name=AluJb |
| ADediting_1377699 | chr7_99968880_- | SINE | Alu | Name=AluJb |
| ADediting_1377700 | chr7_99968881_- | SINE | Alu | Name=AluJb |
| ADediting_1377701 | chr7_99968887_- | SINE | Alu | Name=AluJb |
| ADediting_1377702 | chr7_99968901_- | SINE | Alu | Name=AluJb |
| ADediting_1377703 | chr7_99968922_- | SINE | Alu | Name=AluJb |
| ADediting_1377704 | chr7_99968925_- | SINE | Alu | Name=AluJb |
| ADediting_1377705 | chr7_99968929_- | SINE | Alu | Name=AluJb |
| ADediting_1377706 | chr7_99968930_- | SINE | Alu | Name=AluJb |
| ADediting_1377707 | chr7_99968931_- | SINE | Alu | Name=AluJb |
| ADediting_1377708 | chr7_99968937_- | SINE | Alu | Name=AluJb |
| ADediting_1377709 | chr7_99969082_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377710 | chr7_99969206_- | SINE | Alu | Name=AluSx |
| ADediting_1377711 | chr7_99969217_- | SINE | Alu | Name=AluSx |
| ADediting_1377712 | chr7_99969229_- | SINE | Alu | Name=AluSx |
| ADediting_1377713 | chr7_99969243_- | SINE | Alu | Name=AluSx |
| ADediting_1377714 | chr7_99969297_- | SINE | Alu | Name=AluSx |
| ADediting_1377715 | chr7_99969309_- | SINE | Alu | Name=AluSx |
| ADediting_1377716 | chr7_99969326_- | SINE | Alu | Name=AluSx |
| ADediting_1377717 | chr7_99969327_- | SINE | Alu | Name=AluSx |
| ADediting_1377718 | chr7_99969333_- | SINE | Alu | Name=AluSx |
| ADediting_1377719 | chr7_99969346_- | SINE | Alu | Name=AluSx |
| ADediting_1377720 | chr7_99969347_- | SINE | Alu | Name=AluSx |
| ADediting_1377721 | chr7_99969349_- | SINE | Alu | Name=AluSx |
| ADediting_1377722 | chr7_99969352_- | SINE | Alu | Name=AluSx |
| ADediting_1377723 | chr7_99969517_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377724 | chr7_99970293_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377725 | chr7_99970309_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377726 | chr7_99970310_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377727 | chr7_99970322_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377728 | chr7_99970329_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377729 | chr7_99970333_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377730 | chr7_99970336_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377731 | chr7_99970340_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377732 | chr7_99970341_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377733 | chr7_99970349_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377734 | chr7_99970355_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377735 | chr7_99970365_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377736 | chr7_99970368_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377737 | chr7_99970372_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377738 | chr7_99970376_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377739 | chr7_99970392_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377740 | chr7_99970408_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377741 | chr7_99970411_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377742 | chr7_99970413_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377743 | chr7_99970414_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377744 | chr7_99970416_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377745 | chr7_99970470_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377746 | chr7_99970475_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377747 | chr7_99970476_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377748 | chr7_99970480_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377749 | chr7_99970485_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377750 | chr7_99970489_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377751 | chr7_99970493_- | SINE | Alu | Name=AluSq2 |
| ADediting_1377752 | chr7_99970516_- | SINE | Alu | Name=AluSq2 |
| ADediting_1589288 | chr7_99968835_- | SINE | Alu | Name=AluJb |
| ADediting_1589289 | chr7_99969236_- | SINE | Alu | Name=AluSx |
| ADediting_1589290 | chr7_99969246_- | SINE | Alu | Name=AluSx |
| ADediting_1589291 | chr7_99969523_- | SINE | Alu | Name=AluSq2 |
| ADediting_1589292 | chr7_99970359_- | SINE | Alu | Name=AluSq2 |
| ADediting_1589293 | chr7_99970410_- | SINE | Alu | Name=AluSq2 |
| ADediting_1589294 | chr7_99970412_- | SINE | Alu | Name=AluSq2 |
| ADediting_1589295 | chr7_99970418_- | SINE | Alu | Name=AluSq2 |
| ADediting_1589296 | chr7_99970425_- | SINE | Alu | Name=AluSq2 |
| ADediting_1589297 | chr7_99970436_- | SINE | Alu | Name=AluSq2 |
| ADediting_1589298 | chr7_99970461_- | SINE | Alu | Name=AluSq2 |
| ADediting_1589299 | chr7_99970524_- | SINE | Alu | Name=AluSq2 |
Top |
RNA A-to-I editing events in the alternative splicing sites for AZGP1 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| A3SS | ADediting_1377691 | chr7_99968806_- | 99968793:99968815 | 3ss | 11i | AATTTTTATATTTTTTGTAGTGG | 4.90 | AATTTTTATGTTTTTTGTAGTGG | 5.86 |
| A3SS | ADediting_1377691 | chr7_99968806_- | 99968793:99968815 | 3ss | 11i | AATTTTTATATTTTTTGTAGTGG | 4.90 | AATTTTTATGTTTTTTGTAGTGG | 5.86 |
| A3SS | ADediting_1377692 | chr7_99968808_- | 99968793:99968815 | 3ss | 13i | AATTTTTATATTTTTTGTAGTGG | 4.90 | AATTTTTGTATTTTTTGTAGTGG | 5.32 |
| A3SS | ADediting_1377692 | chr7_99968808_- | 99968793:99968815 | 3ss | 13i | AATTTTTATATTTTTTGTAGTGG | 4.90 | AATTTTTGTATTTTTTGTAGTGG | 5.32 |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for AZGP1 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for AZGP1 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for AZGP1 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_496066 | chr15_66496985_- | ENSG00000160862.13 | ENST00000411734.1 | AZGP1-202 | hsa-miR-4512 | chr7 | 99967249 | 99967256 | 8mer-1a | 99967249 | 99967275 | 141 | -24.25 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000160862.13 | ENST00000292401.9 | AZGP1-201 | hsa-miR-4775 | chr7 | 99966806 | 99966812 | 7mer-m8 | 99966805 | 99966828 | 162 | -15.46 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000160862.13 | ENST00000411734.1 | AZGP1-202 | hsa-miR-4775 | chr7 | 99966806 | 99966812 | 7mer-m8 | 99966805 | 99966828 | 162 | -15.46 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000160862.13 | ENST00000419575.1 | AZGP1-203 | hsa-miR-4775 | chr7 | 99966806 | 99966812 | 7mer-m8 | 99966805 | 99966828 | 162 | -15.46 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_291761 | chr11_93733708_- | ENSG00000160862.13 | ENST00000411734.1 | AZGP1-202 | hsa-miR-1304-3p | chr7 | 99967653 | 99967659 | 7mer-1a | 99967653 | 99967673 | 142 | -19.92 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for AZGP1 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for AZGP1 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_1377685 | chr7_99968737_- | 0.473530811452411 | 0.0408564890705617 | 0.773167334048411 | 0.0164359038491657 | 1.54645396628259e-08 | 0.31434763944674 |
| TCX | ADediting_1377685 | chr7_99968737_- | 0.592113195888828 | -0.0440935250213352 | 0.00118235612996133 | -0.262339237949381 | 5.11690174377814e-10 | 0.480006134538327 |
| TCX | ADediting_1377687 | chr7_99968745_- | 0.828751549936859 | -0.0178086451716124 | 0.000667833313391561 | -0.274741823112819 | 1.32631710793279e-13 | 0.557087138630997 |
| TCX | ADediting_1377688 | chr7_99968746_- | 0.487488273784464 | -0.0571216527661822 | 0.000109741185832911 | -0.310571210325381 | 8.32642744288017e-13 | 0.541544559558709 |
| DLPFC | ADediting_1377689 | chr7_99968778_- | 0.796271065663934 | 0.0147220914110562 | 0.609588085668788 | -0.0291150940555916 | 1.20479040549056e-08 | 0.316598966765253 |
| TCX | ADediting_1377689 | chr7_99968778_- | 0.87962725223961 | -0.0124689961162091 | 0.00087787715701815 | -0.268877101967709 | 1.2969561094325e-09 | 0.469981618981603 |
| DLPFC | ADediting_1377691 | chr7_99968806_- | 0.243776700041447 | 0.0663967126044601 | 0.569904480628539 | 0.0323935387373499 | 1.46918077441325e-09 | 0.33487203786846 |
| TCX | ADediting_1377691 | chr7_99968806_- | 0.794829328337517 | 0.0214092212933789 | 0.0295198162338684 | -0.177777499031647 | 1.42915905677363e-09 | 0.468916512862571 |
| DLPFC | ADediting_1377692 | chr7_99968808_- | 0.243509393649659 | 0.0664342871704616 | 0.699919830228827 | 0.0219770161119758 | 8.0075736085976e-11 | 0.358317696555191 |
| TCX | ADediting_1377692 | chr7_99968808_- | 0.999332237278206 | 6.89104207534148e-05 | 0.0084819690365625 | -0.214214064474637 | 1.00205343354251e-10 | 0.496834652237065 |
| DLPFC | ADediting_1377693 | chr7_99968831_- | 0.135218648396789 | 0.0850339273499327 | 0.981151795472181 | -0.00134724716336768 | 3.3465766199723e-14 | 0.413034844125437 |
| TCX | ADediting_1377693 | chr7_99968831_- | 0.533884362277401 | -0.0511881256999727 | 0.000759112298954077 | -0.272010559766405 | 1.45025711876883e-11 | 0.515665764694201 |
| DLPFC | ADediting_1377694 | chr7_99968839_- | 0.415675722439482 | 0.0463915578348707 | 0.749664708472142 | -0.0181946131707106 | 6.22066082798082e-08 | 0.30143839103236 |
| TCX | ADediting_1377694 | chr7_99968839_- | 0.497235063041692 | -0.0558515298640417 | 0.00742539894067994 | -0.217779200638714 | 6.14525075647857e-07 | 0.393868105368269 |
| TCX | ADediting_1377695 | chr7_99968851_- | 0.272324229711223 | -0.0902006652615443 | 0.000302186354742021 | -0.291055464233735 | 2.71894189421278e-07 | 0.405088271479341 |
| TCX | ADediting_1377696 | chr7_99968854_- | 0.925191755778697 | 0.00773113810072764 | 0.182879714303688 | -0.109340813418696 | 0.000173864119839491 | 0.301875443278815 |
| TCX | ADediting_1377698 | chr7_99968868_- | 0.391065702473769 | -0.0705325611276683 | 0.00543127284121616 | -0.225955254787835 | 7.03602676614118e-07 | 0.391964928469216 |
| TCX | ADediting_1377701 | chr7_99968887_- | 0.457255618217011 | -0.0611509088879562 | 0.000305703731517413 | -0.290824323059453 | 1.85430934935435e-07 | 0.410215947365528 |
| TCX | ADediting_1377705 | chr7_99968929_- | 0.59414120856112 | -0.0438524814928847 | 0.0198537960533351 | -0.190023688607646 | 1.90694846624331e-05 | 0.341403051180782 |
| TCX | ADediting_1377709 | chr7_99969082_- | 0.917356484025973 | -0.00854362777837222 | 0.250514744793706 | -0.0944036519844427 | 0.000101710926329858 | 0.311981623066836 |
| TCX | ADediting_1377710 | chr7_99969206_- | 0.537266232868477 | 0.0507661241610076 | 0.168029583189399 | -0.113143897738206 | 1.39677335682551e-06 | 0.382136459607649 |
| TCX | ADediting_1377711 | chr7_99969217_- | 0.669795551755283 | -0.0351006510811111 | 0.00138942464251528 | -0.258726060039976 | 1.79132881462754e-13 | 0.554598552527429 |
| DLPFC | ADediting_1377714 | chr7_99969297_- | 0.038337898442446 | 0.117703881902356 | 0.595362443738246 | 0.0302787927055992 | 7.75896141406116e-15 | 0.42227800620157 |
| TCX | ADediting_1377714 | chr7_99969297_- | 0.886022626660273 | -0.0118018835977116 | 0.0387106071816019 | -0.168988008511051 | 4.93880359108681e-07 | 0.396916055862164 |
| TCX | ADediting_1377716 | chr7_99969326_- | 0.72374821828195 | 0.0290966814105624 | 0.0425612585045547 | -0.165823691297105 | 1.27907339406229e-06 | 0.383416192920158 |
| TCX | ADediting_1377717 | chr7_99969327_- | 0.123695830055892 | 0.12624775808 | 0.585169040308248 | -0.0449217495865286 | 1.78067984572504e-05 | 0.342545486996997 |
| TCX | ADediting_1377718 | chr7_99969333_- | 0.305987480821818 | -0.0841384862552382 | 0.000558474388521919 | -0.278508110444315 | 1.03391354344112e-09 | 0.47245472791138 |
| TCX | ADediting_1377721 | chr7_99969349_- | 0.250855511079018 | -0.094336086486184 | 0.00131339469098276 | -0.259991728766615 | 4.13311928207588e-08 | 0.429540195718598 |
| TCX | ADediting_1377724 | chr7_99970293_- | 0.828023631127284 | -0.0178855308406804 | 0.0016134800425539 | -0.255333116535578 | 5.16763498231153e-11 | 0.503416571573957 |
| TCX | ADediting_1377727 | chr7_99970322_- | 0.18575318250005 | -0.108631406075216 | 0.00257123609042515 | -0.244458849301174 | 8.20180049118274e-06 | 0.355171864529037 |
| TCX | ADediting_1377730 | chr7_99970336_- | 0.372937551650057 | -0.0732636275212367 | 0.00111267938580678 | -0.263686205989697 | 2.51104955249408e-10 | 0.487465803180211 |
| DLPFC | ADediting_1377734 | chr7_99970355_- | 0.717738948746164 | -0.0206118995993087 | 0.151077706844803 | -0.0817379767419384 | 5.0639476003343e-08 | 0.30338617335824 |
| TCX | ADediting_1377734 | chr7_99970355_- | 0.382063351341727 | -0.0718789601487313 | 0.00344011654688579 | -0.237419208410109 | 5.46154423925594e-09 | 0.45381950439363 |
| TCX | ADediting_1377736 | chr7_99970368_- | 0.330323826111256 | -0.0800247099685028 | 0.00241165824427837 | -0.245981976419397 | 1.51049694321118e-07 | 0.412928602025393 |
| TCX | ADediting_1377739 | chr7_99970392_- | 0.687193806812764 | -0.0331458000294665 | 0.00288656911168733 | -0.241685231059698 | 1.154039716464e-10 | 0.495412760134284 |
| TCX | ADediting_1377742 | chr7_99970413_- | 0.495349437473726 | -0.0560962127342013 | 0.00364182592669839 | -0.23601772358843 | 9.10322714861311e-06 | 0.353504702174244 |
| TCX | ADediting_1377744 | chr7_99970416_- | 0.602943180850359 | -0.0428105770420981 | 0.0379777393304482 | -0.169619994359555 | 3.16512088450697e-05 | 0.332811420338263 |
| DLPFC | ADediting_1377746 | chr7_99970475_- | 0.0332528419314086 | 0.120964355588577 | 0.788019033159914 | 0.0153326211286534 | 8.11770977134739e-13 | 0.391821970322989 |
| TCX | ADediting_1377746 | chr7_99970475_- | 0.0643070402456205 | -0.151449956685131 | 3.35162055429032e-05 | -0.331824396586066 | 1.0231339730345e-08 | 0.446490349521492 |
| DLPFC | ADediting_1377747 | chr7_99970476_- | 0.152873159061791 | 0.0813816953446522 | 0.757188016129459 | -0.0176298448470692 | 9.35927598646644e-13 | 0.390838973923991 |
| TCX | ADediting_1377747 | chr7_99970476_- | 0.123821308920544 | -0.126205932743379 | 0.000112692797735046 | -0.310076927931611 | 1.54270835379126e-09 | 0.468075012776008 |
| DLPFC | ADediting_1377748 | chr7_99970480_- | 0.276471078455519 | 0.0620011922660573 | 0.282553505730591 | -0.0612232793729808 | 4.96895137062809e-14 | 0.41048565365692 |
| TCX | ADediting_1377748 | chr7_99970480_- | 0.119235119295591 | -0.127756412727588 | 2.95509087806818e-05 | -0.333990704604006 | 5.89966125020374e-10 | 0.478492691841548 |
| DLPFC | ADediting_1377749 | chr7_99970485_- | 0.0812711314666534 | 0.0991724752486311 | 0.866996208739426 | 0.00955031265651541 | 1.48319894380332e-10 | 0.353509712111125 |
| TCX | ADediting_1377749 | chr7_99970485_- | 0.443466267531776 | -0.0630375351456026 | 0.00047258959162937 | -0.281977645093389 | 1.05776493797624e-08 | 0.446096817265843 |
| TCX | ADediting_1377750 | chr7_99970489_- | 0.207207137374393 | -0.103572500730089 | 0.00786232278172948 | -0.216253586067163 | 9.50878339476994e-05 | 0.313225492527494 |
| TCX | ADediting_1377753 | chr7_99971443_- | 0.760929025208609 | -0.0250484529608693 | 0.0104660408436822 | -0.208468456800631 | 1.17120373260192e-08 | 0.444889338206371 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| AC | 2.25105513751704e-15 | 0.473493524077305 | 1.75331059124484e-07 | 0.323095079892019 | 1.69311531188467e-41 | 0.721663235046882 |
| PCC | 0.843907100891863 | 0.0143404655571373 | 0.97938820993329 | 0.00188177257977497 | 7.78461404872678e-07 | 0.348511490340639 |
| TCX | 0.425819691604105 | 0.0655010399801721 | 0.000569298218420524 | -0.278106371494197 | 2.00553756621148e-22 | 0.688780184286223 |
| FP | 0.011169887827137 | 0.189786959344138 | 0.00732364409000196 | 0.200375224879814 | 4.25590563821763e-13 | 0.50854890521738 |
| IFG | 0.910677840345302 | -0.0236441435582157 | 0.773685883607684 | -0.0605590185342176 | 0.01512539105903 | 0.480181429756978 |
| PG | 0.00470220031034578 | 0.206422405302531 | 0.511447370382098 | 0.0484414810658369 | 1.60770647137068e-15 | 0.54081696806751 |
| STG | 0.331801320708163 | 0.107190003671987 | 0.7810459460275 | 0.0307815530493411 | 1.12539033012736e-05 | 0.459015517652019 |
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Relation with AD stages for AZGP1 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| TCX | ADediting_1377685 | chr7_99968737_- | 0.000290256909449685 | 0.345188381487155 |
| TCX | ADediting_1377687 | chr7_99968745_- | 5.14747525802835e-05 | 0.382714018613295 |
| TCX | ADediting_1377688 | chr7_99968746_- | 0.000541333330851201 | 0.330436720800484 |
| TCX | ADediting_1377689 | chr7_99968778_- | 0.000378167938615551 | 0.339015277297969 |
| TCX | ADediting_1377692 | chr7_99968808_- | 0.0014461444952924 | 0.305569729193794 |
| TCX | ADediting_1377694 | chr7_99968839_- | 0.00143966024213196 | 0.305688434098841 |
| TCX | ADediting_1377716 | chr7_99969326_- | 0.000301430731913354 | 0.3443147694169 |
| TCX | ADediting_1377717 | chr7_99969327_- | 0.000160098117806807 | 0.358624849920724 |
| TCX | ADediting_1377718 | chr7_99969333_- | 7.74910374688003e-05 | 0.374246129074684 |
| TCX | ADediting_1377721 | chr7_99969349_- | 0.00081330982690259 | 0.320390083154794 |
| TCX | ADediting_1377741 | chr7_99970411_- | 0.000304324704397621 | 0.344093383298852 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| TCX | 2.29568161221494e-06 | 0.440507297357267 |
| PG | 1.57368967554301e-05 | 0.310835980205725 |
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RelatedDrugs for AZGP1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for AZGP1 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| AZGP1 | C0001418 | Adenocarcinoma | 1 | CTD_human |
| AZGP1 | C0024121 | Lung Neoplasms | 1 | CTD_human |
| AZGP1 | C0032460 | Polycystic Ovary Syndrome | 1 | CTD_human |
| AZGP1 | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| AZGP1 | C0037199 | Sinusitis | 1 | CTD_human |
| AZGP1 | C0205641 | Adenocarcinoma, Basal Cell | 1 | CTD_human |
| AZGP1 | C0205642 | Adenocarcinoma, Oxyphilic | 1 | CTD_human |
| AZGP1 | C0205643 | Carcinoma, Cribriform | 1 | CTD_human |
| AZGP1 | C0205644 | Carcinoma, Granular Cell | 1 | CTD_human |
| AZGP1 | C0205645 | Adenocarcinoma, Tubular | 1 | CTD_human |
| AZGP1 | C0242379 | Malignant neoplasm of lung | 1 | CTD_human |
| AZGP1 | C0376358 | Malignant neoplasm of prostate | 1 | CTD_human |
| AZGP1 | C1136382 | Sclerocystic Ovaries | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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