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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for PRKX

check button Gene summary
Gene informationGene symbol

PRKX

Gene ID

5613

Gene nameprotein kinase X-linked
SynonymsPKX1
Cytomap

Xp22.33

Type of geneprotein-coding
DescriptioncAMP-dependent protein kinase catalytic subunit PRKXprotein kinase PKX1protein kinase Xserine/threonine-protein kinase PRKX
Modification date20200313
UniProtAcc

P51817,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
PRKX

GO:0018105

peptidyl-serine phosphorylation

16491121

PRKX

GO:0030099

myeloid cell differentiation

9860982

PRKX

GO:0030155

regulation of cell adhesion

17980165

PRKX

GO:0030334

regulation of cell migration

17980165

PRKX

GO:0046777

protein autophosphorylation

10026146|16491121

PRKX

GO:0060562

epithelial tube morphogenesis

17980165

PRKX

GO:0060993

kidney morphogenesis

17980165

PRKX

GO:2000696

regulation of epithelial cell differentiation involved in kidney development

17980165


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RNA A-to-I events for PRKX

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_1499701(3606446, -), ADediting_1499702(3609191, -), ADediting_1499703(3609222, -), ADediting_1499704(3609224, -), ADediting_1499705(3609285, -), ADediting_1499706(3609289, -), ADediting_1499707(3609298, -), ADediting_1499708(3609299, -), ADediting_1499709(3609362, -), ADediting_1499710(3609364, -), ADediting_1499711(3609365, -), ADediting_1499712(3609374, -), ADediting_1499713(3609433, -), ADediting_1499714(3609434, -), ADediting_1499715(3609643, -), ADediting_1499716(3609654, -), ADediting_1499717(3609706, -), ADediting_1499718(3609735, -), ADediting_1499719(3610236, -), ADediting_1499720(3610289, -), ADediting_1499721(3610298, -), ADediting_1499722(3610314, -), ADediting_1499723(3610317, -), ADediting_1499724(3610339, -), ADediting_1499725(3610342, -), ADediting_1499726(3610360, -), ADediting_1499727(3610370, -), ADediting_1499728(3610382, -), ADediting_1499729(3610399, -), ADediting_1499730(3610419, -), ADediting_1499731(3610430, -), ADediting_1499732(3610435, -), ADediting_1499733(3610476, -), ADediting_1499734(3615128, -), ADediting_1499735(3635648, -), ADediting_1499736(3635712, -), ADediting_1499737(3635817, -), ADediting_1499738(3636657, -), ADediting_1499739(3636675, -), ADediting_1499740(3636784, -), ADediting_1499741(3638041, -), ADediting_1499742(3654599, -), ADediting_1499743(3654613, -), ADediting_1499744(3658129, -), ADediting_1499745(3658173, -), ADediting_1499746(3658194, -), ADediting_1499747(3658209, -), ADediting_1499748(3658218, -), ADediting_1499749(3658223, -), ADediting_1499750(3684169, -), ADediting_1499751(3695654, -), ADediting_1499752(3697097, -), ADediting_1499753(3697109, -), ADediting_1499754(3697110, -), ADediting_1499755(3697133, -), ADediting_1499756(3697135, -), ADediting_1499757(3697151, -), ADediting_1499758(3697161, -), ADediting_1499759(3697169, -), ADediting_1499760(3697366, -), ADediting_1499761(3698685, -), ADediting_1499762(3698696, -), ADediting_1499763(3701233, -), ADediting_1499764(3701324, -), ADediting_1499765(3704421, -), ADediting_1499766(3704591, -), ADediting_1499767(3705182, -), ADediting_1499768(3705253, -), ADediting_1499769(3706313, -), ADediting_1499770(3706388, -), ADediting_1499771(3706408, -), ADediting_1499772(3706415, -), ADediting_1499773(3706921, -), ADediting_1499774(3707032, -), ADediting_1499775(3707065, -), ADediting_1499776(3707070, -), ADediting_1499777(3707075, -), ADediting_1499778(3707081, -), ADediting_1499779(3707114, -), ADediting_1499780(3708764, -), ADediting_1499781(3710653, -), ADediting_1595173(3609595, -), ADediting_1595174(3609609, -), ADediting_1595175(3609728, -), ADediting_1595176(3609729, -), ADediting_1595177(3610224, -), ADediting_1595178(3658185, -),

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RNA editing positional annotations for PRKX using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_1499701chrX_3606446_-UTR3
ADediting_1499702chrX_3609191_-intronic
ADediting_1499703chrX_3609222_-intronic
ADediting_1499704chrX_3609224_-intronic
ADediting_1499705chrX_3609285_-intronic
ADediting_1499706chrX_3609289_-intronic
ADediting_1499707chrX_3609298_-intronic
ADediting_1499708chrX_3609299_-intronic
ADediting_1499709chrX_3609362_-intronic
ADediting_1499710chrX_3609364_-intronic
ADediting_1499711chrX_3609365_-intronic
ADediting_1499712chrX_3609374_-intronic
ADediting_1499713chrX_3609433_-intronic
ADediting_1499714chrX_3609434_-intronic
ADediting_1499715chrX_3609643_-intronic
ADediting_1499716chrX_3609654_-intronic
ADediting_1499717chrX_3609706_-intronic
ADediting_1499718chrX_3609735_-intronic
ADediting_1499719chrX_3610236_-intronic
ADediting_1499720chrX_3610289_-intronic
ADediting_1499721chrX_3610298_-intronic
ADediting_1499722chrX_3610314_-intronic
ADediting_1499723chrX_3610317_-intronic
ADediting_1499724chrX_3610339_-intronic
ADediting_1499725chrX_3610342_-intronic
ADediting_1499726chrX_3610360_-intronic
ADediting_1499727chrX_3610370_-intronic
ADediting_1499728chrX_3610382_-intronic
ADediting_1499729chrX_3610399_-intronic
ADediting_1499730chrX_3610419_-intronic
ADediting_1499731chrX_3610430_-intronic
ADediting_1499732chrX_3610435_-intronic
ADediting_1499733chrX_3610476_-intronic
ADediting_1499734chrX_3615128_-intronic
ADediting_1499735chrX_3635648_-intronic
ADediting_1499736chrX_3635712_-intronic
ADediting_1499737chrX_3635817_-intronic
ADediting_1499738chrX_3636657_-intronic
ADediting_1499739chrX_3636675_-intronic
ADediting_1499740chrX_3636784_-intronic
ADediting_1499741chrX_3638041_-intronic
ADediting_1499742chrX_3654599_-intronic
ADediting_1499743chrX_3654613_-intronic
ADediting_1499744chrX_3658129_-intronic
ADediting_1499745chrX_3658173_-intronic
ADediting_1499746chrX_3658194_-intronic
ADediting_1499747chrX_3658209_-intronic
ADediting_1499748chrX_3658218_-intronic
ADediting_1499749chrX_3658223_-intronic
ADediting_1499750chrX_3684169_-intronic
ADediting_1499751chrX_3695654_-intronic
ADediting_1499752chrX_3697097_-intronic
ADediting_1499753chrX_3697109_-intronic
ADediting_1499754chrX_3697110_-intronic
ADediting_1499755chrX_3697133_-intronic
ADediting_1499756chrX_3697135_-intronic
ADediting_1499757chrX_3697151_-intronic
ADediting_1499758chrX_3697161_-intronic
ADediting_1499759chrX_3697169_-intronic
ADediting_1499760chrX_3697366_-intronic
ADediting_1499761chrX_3698685_-intronic
ADediting_1499762chrX_3698696_-intronic
ADediting_1499763chrX_3701233_-intronic
ADediting_1499764chrX_3701324_-intronic
ADediting_1499765chrX_3704421_-intronic
ADediting_1499766chrX_3704591_-intronic
ADediting_1499767chrX_3705182_-intronic
ADediting_1499768chrX_3705253_-intronic
ADediting_1499769chrX_3706313_-intronic
ADediting_1499770chrX_3706388_-intronic
ADediting_1499771chrX_3706408_-intronic
ADediting_1499772chrX_3706415_-intronic
ADediting_1499773chrX_3706921_-intronic
ADediting_1499774chrX_3707032_-intronic
ADediting_1499775chrX_3707065_-intronic
ADediting_1499776chrX_3707070_-intronic
ADediting_1499777chrX_3707075_-intronic
ADediting_1499778chrX_3707081_-intronic
ADediting_1499779chrX_3707114_-intronic
ADediting_1499780chrX_3708764_-intronic
ADediting_1499781chrX_3710653_-intronic
ADediting_1595173chrX_3609595_-intronic
ADediting_1595174chrX_3609609_-intronic
ADediting_1595175chrX_3609728_-intronic
ADediting_1595176chrX_3609729_-intronic
ADediting_1595177chrX_3610224_-intronic
ADediting_1595178chrX_3658185_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_1499701chrX_3606446_-SINEAluName=AluSx1
ADediting_1499702chrX_3609191_-SINEAluName=AluSq
ADediting_1499703chrX_3609222_-SINEAluName=AluSq
ADediting_1499704chrX_3609224_-SINEAluName=AluSq
ADediting_1499705chrX_3609285_-SINEAluName=AluSq
ADediting_1499706chrX_3609289_-SINEAluName=AluSq
ADediting_1499707chrX_3609298_-SINEAluName=AluSq
ADediting_1499708chrX_3609299_-SINEAluName=AluSq
ADediting_1499709chrX_3609362_-SINEAluName=AluSq
ADediting_1499710chrX_3609364_-SINEAluName=AluSq
ADediting_1499711chrX_3609365_-SINEAluName=AluSq
ADediting_1499712chrX_3609374_-SINEAluName=AluSq
ADediting_1499713chrX_3609433_-SINEAluName=AluSq
ADediting_1499714chrX_3609434_-SINEAluName=AluSq
ADediting_1499715chrX_3609643_-SINEAluName=AluJb
ADediting_1499716chrX_3609654_-SINEAluName=AluJb
ADediting_1499717chrX_3609706_-SINEAluName=AluJb
ADediting_1499718chrX_3609735_-SINEAluName=AluJb
ADediting_1499719chrX_3610236_-SINEAluName=AluSx1
ADediting_1499720chrX_3610289_-SINEAluName=AluSx1
ADediting_1499721chrX_3610298_-SINEAluName=AluSx1
ADediting_1499722chrX_3610314_-SINEAluName=AluSx1
ADediting_1499723chrX_3610317_-SINEAluName=AluSx1
ADediting_1499724chrX_3610339_-SINEAluName=AluSx1
ADediting_1499725chrX_3610342_-SINEAluName=AluSx1
ADediting_1499726chrX_3610360_-SINEAluName=AluSx1
ADediting_1499727chrX_3610370_-SINEAluName=AluSx1
ADediting_1499728chrX_3610382_-SINEAluName=AluSx1
ADediting_1499729chrX_3610399_-SINEAluName=AluSx1
ADediting_1499730chrX_3610419_-SINEAluName=AluSx1
ADediting_1499731chrX_3610430_-SINEAluName=AluSx1
ADediting_1499732chrX_3610435_-SINEAluName=AluSx1
ADediting_1499733chrX_3610476_-SINEAluName=AluSx1
ADediting_1499734chrX_3615128_-SINEAluName=AluJb
ADediting_1499735chrX_3635648_-SINEAluName=AluJo
ADediting_1499736chrX_3635712_-SINEAluName=AluJo
ADediting_1499737chrX_3635817_-SINEAluName=AluJo
ADediting_1499738chrX_3636657_-SINEAluName=AluSz
ADediting_1499739chrX_3636675_-SINEAluName=AluSz
ADediting_1499740chrX_3636784_-SINEAluName=AluSz
ADediting_1499741chrX_3638041_-SINEAluName=AluSx1
ADediting_1499742chrX_3654599_-SINEAluName=AluJb
ADediting_1499743chrX_3654613_-SINEAluName=AluJb
ADediting_1499744chrX_3658129_-SINEAluName=AluSq2
ADediting_1499745chrX_3658173_-SINEAluName=AluSq2
ADediting_1499746chrX_3658194_-SINEAluName=AluSq2
ADediting_1499747chrX_3658209_-SINEAluName=AluSq2
ADediting_1499748chrX_3658218_-SINEAluName=AluSq2
ADediting_1499749chrX_3658223_-SINEAluName=AluSq2
ADediting_1499750chrX_3684169_-SINEAluName=AluSg
ADediting_1499751chrX_3695654_-SINEAluName=AluJo
ADediting_1499752chrX_3697097_-SINEAluName=AluJb
ADediting_1499753chrX_3697109_-SINEAluName=AluJb
ADediting_1499754chrX_3697110_-SINEAluName=AluJb
ADediting_1499755chrX_3697133_-SINEAluName=AluJb
ADediting_1499756chrX_3697135_-SINEAluName=AluJb
ADediting_1499757chrX_3697151_-SINEAluName=AluJb
ADediting_1499758chrX_3697161_-SINEAluName=AluJb
ADediting_1499759chrX_3697169_-SINEAluName=AluJb
ADediting_1499760chrX_3697366_-SINEAluName=AluJb
ADediting_1499761chrX_3698685_-SINEAluName=AluSx1
ADediting_1499762chrX_3698696_-SINEAluName=AluSx1
ADediting_1499763chrX_3701233_-SINEAluName=AluJr
ADediting_1499764chrX_3701324_-SINEAluName=AluJr
ADediting_1499765chrX_3704421_-SINEAluName=AluJb
ADediting_1499766chrX_3704591_-SINEAluName=AluJb
ADediting_1499767chrX_3705182_-LTRERVL-MaLRName=MLT1A0
ADediting_1499768chrX_3705253_-LTRERVL-MaLRName=MLT1A0
ADediting_1499769chrX_3706313_-SINEAluName=AluJo
ADediting_1499770chrX_3706388_-SINEAluName=AluJo
ADediting_1499771chrX_3706408_-SINEAluName=AluJo
ADediting_1499772chrX_3706415_-SINEAluName=AluJo
ADediting_1499773chrX_3706921_-SINEAluName=AluJb
ADediting_1499774chrX_3707032_-SINEAluName=AluJb
ADediting_1499775chrX_3707065_-SINEAluName=AluJb
ADediting_1499776chrX_3707070_-SINEAluName=AluJb
ADediting_1499777chrX_3707075_-SINEAluName=AluJb
ADediting_1499778chrX_3707081_-SINEAluName=AluJb
ADediting_1499779chrX_3707114_-SINEAluName=AluJb
ADediting_1499780chrX_3708764_-SINEAluName=AluSp
ADediting_1499781chrX_3710653_-SINEAluName=AluSx1
ADediting_1595173chrX_3609595_-SINEAluName=AluJb
ADediting_1595174chrX_3609609_-SINEAluName=AluJb
ADediting_1595175chrX_3609728_-SINEAluName=AluJb
ADediting_1595176chrX_3609729_-SINEAluName=AluJb
ADediting_1595177chrX_3610224_-SINEAluName=AluSx1
ADediting_1595178chrX_3658185_-SINEAluName=AluSq2

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RNA A-to-I editing events in the alternative splicing sites for PRKX

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for PRKX

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
Soverview
Soverview
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

Soverview
Soverview
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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for PRKX

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


Top

The effects of the RNA editing to the miRNA binding sites for PRKX

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1499701chrX_3606446_-ENSG00000183943.6ENST00000262848.6PRKX-201hsa-miR-4638-5pchrX360644436064518mer-1a36064443606465148-18.05

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337757chr7_5495852_-ENSG00000183943.6ENST00000262848.6PRKX-201hsa-miR-589-3pchrX360474136047488mer-1a36047413604765152-14.6
ADediting_1337757chr7_5495852_-ENSG00000183943.6ENST00000262848.6PRKX-201hsa-miR-589-3pchrX360489536049017mer-m836048943604915147-16.2
ADediting_1596844chr1_162342605_+ENSG00000183943.6ENST00000262848.6PRKX-201hsa-miR-556-3pchrX360613036061367mer-m836061293606147146-13.94
ADediting_527135chr16_24203190_+ENSG00000183943.6ENST00000262848.6PRKX-201hsa-miR-1273h-3pchrX360629636063027mer-m836062953606320144-17.99
ADediting_527135chr16_24203190_+ENSG00000183943.6ENST00000262848.6PRKX-201hsa-miR-1273h-3pchrX360633536063417mer-m836063343606359142-20.54
ADediting_843620chr2_207754818_+ENSG00000183943.6ENST00000262848.6PRKX-201hsa-miR-4775chrX360560236056087mer-m836056013605622160-8.76
ADediting_843620chr2_207754818_+ENSG00000183943.6ENST00000262848.6PRKX-201hsa-miR-4775chrX360840736084137mer-m836084063608427152-6.55
ADediting_98289chr1_32086992_+ENSG00000183943.6ENST00000262848.6PRKX-201hsa-miR-5585-3pchrX360572236057287mer-m836057213605739148-17.17

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_107020chr1_37500952_-ENSG00000183943.6ENST00000262848.6PRKX-201hsa-miR-5581-3pchrX360629236062987mer-m836062913606312140-11.33
ADediting_107020chr1_37500952_-ENSG00000183943.6ENST00000262848.6PRKX-201hsa-miR-5581-3pchrX360633136063377mer-m836063303606351140-9.15
ADediting_1097295chr3_85385762_+ENSG00000183943.6ENST00000262848.6PRKX-201hsa-miR-5688chrX360449036044967mer-m836044893604514148-11.04
ADediting_1337757chr7_5495852_-ENSG00000183943.6ENST00000262848.6PRKX-201hsa-miR-589-3pchrX360481236048187mer-m836048113604833154-21.57
ADediting_1556067chr19_40282625_-ENSG00000183943.6ENST00000262848.6PRKX-201hsa-miR-641chrX360887836088847mer-m836088773608900140-9.63
ADediting_1631458chr19_40282624_-ENSG00000183943.6ENST00000262848.6PRKX-201hsa-miR-641chrX360887836088847mer-m836088773608900140-9.63
ADediting_843620chr2_207754818_+ENSG00000183943.6ENST00000262848.6PRKX-201hsa-miR-4775chrX360713536071417mer-m836071343607155145-4.12

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for PRKX

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000262848.6protein_codingSoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_1499701ENST00000262848.6chrX_3606446_-3996-1995.70-1995.70-1995.70

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for PRKX

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_1499704chrX_3609224_-0.008185202485761740.1499437657513490.3857753727583280.04942913078177296.54332530416142e-130.393304935225657
TCXADediting_1499716chrX_3609654_-0.6145522594372540.04144667830303350.433736926940371-0.06438869254787947.48431184476426e-050.31760425123728
TCXADediting_1499718chrX_3609735_-0.05177276432254310.1591278377997630.523777580844459-0.05245734152448349.03214289939031e-090.447959751392342
DLPFCADediting_1499723chrX_3610317_-0.0261879572922370.1262855574156580.982946398892530.001218950586673933.72234612064672e-200.490326570595514
DLPFCADediting_1499726chrX_3610360_-0.007152965736905160.1524828402386030.571358839576816-0.03227155318118182.00463763177195e-270.563949923729548
DLPFCADediting_1499727chrX_3610370_-0.00607913813403110.1554985767509340.8239337335833610.01268723444280374.1127379893706e-240.53261406911247
DLPFCADediting_1499728chrX_3610382_-0.04940360239239690.1117114299772790.781097717958773-0.01584604668748712.53786748892072e-140.414805995052707
DLPFCADediting_1499733chrX_3610476_-0.0424297021672410.1153364357469130.581179195945532-0.03145166295955373.84035585555287e-170.453654063116414
TCXADediting_1499733chrX_3610476_-0.6926427610459850.0325373994991430.0118730607423354-0.2049510149270911.02072924103492e-080.446518149658166

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC0.0792698063118090.09982797627880530.760425800635211-0.01738731911488529.93611060486085e-250.538705353440436
AC3.06637280257026e-270.6134708795219262.75445137170478e-140.4567169369111251.03418999295395e-250.598766101427974
PCC0.1082922231160290.1165687541944430.3316822339059430.0706154445669528.85397599897119e-110.447188355672206
CER6.4764452585055e-080.42388398155678.3861019816651e-070.3894791291748472.56584588031654e-210.675380823084684
TCX0.05053087858022850.1599696722311850.00141377652238242-0.2583340298759241.47721655449389e-240.712702300290575
FP0.004750717093616360.210730763253530.1025517917301080.1227706132430391.12883898397807e-210.637318925268332
IFG0.883748633811250.03081449151771610.5784834225487480.1167146760477580.004347592823304670.550549275495962
PG1.23005142162211e-100.4494838199552282.78405811389388e-060.3358359617873250.0001052940557873820.280513506685864
STG0.9988701110427990.0001568602687237350.143602064197464-0.1609419632007336.39310101196529e-130.68538557929755

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Relation with AD stages for PRKX

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
CER5.70469113042494e-090.524411671169853
TCX2.57389322500973e-100.565981931757004
PG3.25821605675848e-130.501031066531414

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RelatedDrugs for PRKX

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for PRKX

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource