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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for ZNF415 |
 Gene summary |
| Gene information | Gene symbol | ZNF415 | Gene ID | 55786 |
| Gene name | zinc finger protein 415 | |
| Synonyms | Pact|ZfLp | |
| Cytomap | 19q13.42 | |
| Type of gene | protein-coding | |
| Description | zinc finger protein 415 | |
| Modification date | 20200313 | |
| UniProtAcc | Q09FC8, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for ZNF415 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_780790(53111435, -), ADediting_780791(53111525, -), ADediting_780792(53111632, -), ADediting_780793(53112052, -), ADediting_780794(53112147, -), ADediting_780796(53113034, -), ADediting_780797(53114237, -), ADediting_780798(53114269, -), ADediting_780799(53115235, -), ADediting_780800(53115272, -), ADediting_780801(53115288, -), ADediting_780802(53116692, -), ADediting_780803(53116718, -), ADediting_780804(53117358, -), ADediting_780805(53117378, -), ADediting_780806(53117402, -), ADediting_780807(53121322, -), ADediting_780808(53121506, -), ADediting_780809(53121512, -), ADediting_780810(53121552, -), ADediting_780811(53121592, -), ADediting_780812(53121650, -), ADediting_780813(53121668, -), ADediting_780814(53121697, -), ADediting_780815(53122002, -), ADediting_780816(53122021, -), ADediting_780817(53123981, -), ADediting_780823(53125181, -), ADediting_780824(53125208, -), ADediting_780825(53125217, -), ADediting_780826(53125367, -), ADediting_780827(53125403, -), ADediting_780828(53125458, -), ADediting_780829(53125473, -), ADediting_780830(53125514, -), ADediting_780831(53125537, -), ADediting_780832(53125546, -), ADediting_780833(53125735, -), ADediting_780835(53125750, -), ADediting_780836(53125755, -), ADediting_780837(53125772, -), ADediting_780838(53125775, -), ADediting_780840(53125789, -), ADediting_780841(53125816, -), ADediting_780842(53125886, -), ADediting_780843(53125922, -), ADediting_780844(53127644, -), ADediting_780845(53127755, -), ADediting_780846(53127765, -), ADediting_780847(53129828, -), ADediting_780848(53129891, -), ADediting_780849(53129894, -), ADediting_780850(53129943, -), ADediting_780851(53129953, -), ADediting_780852(53130018, -), ADediting_780853(53130778, -), ADediting_780854(53130783, -), ADediting_780855(53130784, -), ADediting_780856(53130802, -), ADediting_780857(53130819, -), ADediting_780858(53130916, -), ADediting_780859(53130925, -), ADediting_1558748(53115213, -), ADediting_1558749(53120829, -), ADediting_1558750(53125513, -), ADediting_1558751(53127777, -), ADediting_1558752(53130849, -), ADediting_1631664(53116731, -), ADediting_1631665(53116732, -), ADediting_1631666(53116736, -), |
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RNA editing positional annotations for ZNF415 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| ADediting_780799 | chr19_53115235_- | nonsynonymous SNV | ENST00000599261.5 | c.A317G | p.Q106R | . | . | . |
| ADediting_780799 | chr19_53115235_- | nonsynonymous SNV | ENST00000597748.5 | c.A209G | p.Q70R | . | . | . |
| ADediting_780799 | chr19_53115235_- | nonsynonymous SNV | ENST00000595193.5 | c.A317G | p.Q106R | . | . | . |
| ADediting_780799 | chr19_53115235_- | nonsynonymous SNV | ENST00000597503.5 | c.A209G | p.Q70R | . | . | . |
| ADediting_780799 | chr19_53115235_- | nonsynonymous SNV | ENST00000595813.5 | c.A209G | p.Q70R | . | . | . |
| ADediting_780799 | chr19_53115235_- | nonsynonymous SNV | ENST00000594011.5 | c.A317G | p.Q106R | . | . | . |
| ADediting_780800 | chr19_53115272_- | nonsynonymous SNV | ENST00000599261.5 | c.A280G | p.T94A | . | . | . |
| ADediting_780800 | chr19_53115272_- | nonsynonymous SNV | ENST00000597748.5 | c.A172G | p.T58A | . | . | . |
| ADediting_780800 | chr19_53115272_- | nonsynonymous SNV | ENST00000595193.5 | c.A280G | p.T94A | . | . | . |
| ADediting_780800 | chr19_53115272_- | nonsynonymous SNV | ENST00000597503.5 | c.A172G | p.T58A | . | . | . |
| ADediting_780800 | chr19_53115272_- | nonsynonymous SNV | ENST00000595813.5 | c.A172G | p.T58A | . | . | . |
| ADediting_780800 | chr19_53115272_- | nonsynonymous SNV | ENST00000594011.5 | c.A280G | p.T94A | . | . | . |
| ADediting_780801 | chr19_53115288_- | synonymous SNV | ENST00000599261.5 | c.A264G | p.Q88Q | . | . | . |
| ADediting_780801 | chr19_53115288_- | synonymous SNV | ENST00000597748.5 | c.A156G | p.Q52Q | . | . | . |
| ADediting_780801 | chr19_53115288_- | synonymous SNV | ENST00000595193.5 | c.A264G | p.Q88Q | . | . | . |
| ADediting_780801 | chr19_53115288_- | synonymous SNV | ENST00000597503.5 | c.A156G | p.Q52Q | . | . | . |
| ADediting_780801 | chr19_53115288_- | synonymous SNV | ENST00000595813.5 | c.A156G | p.Q52Q | . | . | . |
| ADediting_780801 | chr19_53115288_- | synonymous SNV | ENST00000594011.5 | c.A264G | p.Q88Q | . | . | . |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_780790 | chr19_53111435_- | intronic |
| ADediting_780791 | chr19_53111525_- | intronic |
| ADediting_780792 | chr19_53111632_- | intronic |
| ADediting_780793 | chr19_53112052_- | intronic |
| ADediting_780794 | chr19_53112147_- | intronic |
| ADediting_780796 | chr19_53113034_- | intronic |
| ADediting_780797 | chr19_53114237_- | intronic |
| ADediting_780798 | chr19_53114269_- | intronic |
| ADediting_780799 | chr19_53115235_- | exonic |
| ADediting_780800 | chr19_53115272_- | exonic |
| ADediting_780801 | chr19_53115288_- | exonic |
| ADediting_780802 | chr19_53116692_- | intronic |
| ADediting_780803 | chr19_53116718_- | intronic |
| ADediting_780804 | chr19_53117358_- | intronic |
| ADediting_780805 | chr19_53117378_- | intronic |
| ADediting_780806 | chr19_53117402_- | intronic |
| ADediting_780807 | chr19_53121322_- | intronic |
| ADediting_780808 | chr19_53121506_- | intronic |
| ADediting_780809 | chr19_53121512_- | intronic |
| ADediting_780810 | chr19_53121552_- | intronic |
| ADediting_780811 | chr19_53121592_- | intronic |
| ADediting_780812 | chr19_53121650_- | intronic |
| ADediting_780813 | chr19_53121668_- | intronic |
| ADediting_780814 | chr19_53121697_- | intronic |
| ADediting_780815 | chr19_53122002_- | intronic |
| ADediting_780816 | chr19_53122021_- | intronic |
| ADediting_780817 | chr19_53123981_- | intronic |
| ADediting_780823 | chr19_53125181_- | intronic |
| ADediting_780824 | chr19_53125208_- | intronic |
| ADediting_780825 | chr19_53125217_- | intronic |
| ADediting_780826 | chr19_53125367_- | intronic |
| ADediting_780827 | chr19_53125403_- | intronic |
| ADediting_780828 | chr19_53125458_- | intronic |
| ADediting_780829 | chr19_53125473_- | intronic |
| ADediting_780830 | chr19_53125514_- | intronic |
| ADediting_780831 | chr19_53125537_- | intronic |
| ADediting_780832 | chr19_53125546_- | intronic |
| ADediting_780833 | chr19_53125735_- | intronic |
| ADediting_780835 | chr19_53125750_- | intronic |
| ADediting_780836 | chr19_53125755_- | intronic |
| ADediting_780837 | chr19_53125772_- | intronic |
| ADediting_780838 | chr19_53125775_- | intronic |
| ADediting_780840 | chr19_53125789_- | intronic |
| ADediting_780841 | chr19_53125816_- | intronic |
| ADediting_780842 | chr19_53125886_- | intronic |
| ADediting_780843 | chr19_53125922_- | intronic |
| ADediting_780844 | chr19_53127644_- | intronic |
| ADediting_780845 | chr19_53127755_- | intronic |
| ADediting_780846 | chr19_53127765_- | intronic |
| ADediting_780847 | chr19_53129828_- | intronic |
| ADediting_780848 | chr19_53129891_- | intronic |
| ADediting_780849 | chr19_53129894_- | intronic |
| ADediting_780850 | chr19_53129943_- | intronic |
| ADediting_780851 | chr19_53129953_- | intronic |
| ADediting_780852 | chr19_53130018_- | intronic |
| ADediting_780853 | chr19_53130778_- | intronic |
| ADediting_780854 | chr19_53130783_- | intronic |
| ADediting_780855 | chr19_53130784_- | intronic |
| ADediting_780856 | chr19_53130802_- | intronic |
| ADediting_780857 | chr19_53130819_- | intronic |
| ADediting_780858 | chr19_53130916_- | intronic |
| ADediting_780859 | chr19_53130925_- | intronic |
| ADediting_1558748 | chr19_53115213_- | UTR3 |
| ADediting_1558749 | chr19_53120829_- | intronic |
| ADediting_1558750 | chr19_53125513_- | intronic |
| ADediting_1558751 | chr19_53127777_- | intronic |
| ADediting_1558752 | chr19_53130849_- | intronic |
| ADediting_1631664 | chr19_53116731_- | intronic |
| ADediting_1631665 | chr19_53116732_- | intronic |
| ADediting_1631666 | chr19_53116736_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_780790 | chr19_53111435_- | SINE | Alu | Name=AluSq2 |
| ADediting_780791 | chr19_53111525_- | SINE | Alu | Name=AluSq2 |
| ADediting_780792 | chr19_53111632_- | SINE | Alu | Name=AluSq2 |
| ADediting_780793 | chr19_53112052_- | SINE | Alu | Name=AluSx1 |
| ADediting_780794 | chr19_53112147_- | SINE | Alu | Name=AluSx1 |
| ADediting_780796 | chr19_53113034_- | SINE | Alu | Name=AluSp |
| ADediting_780797 | chr19_53114237_- | SINE | Alu | Name=AluSx |
| ADediting_780798 | chr19_53114269_- | SINE | Alu | Name=AluSx |
| ADediting_780799 | chr19_53115235_- | SINE | Alu | Name=AluSq2 |
| ADediting_780800 | chr19_53115272_- | SINE | Alu | Name=AluSq2 |
| ADediting_780801 | chr19_53115288_- | SINE | Alu | Name=AluSq2 |
| ADediting_780802 | chr19_53116692_- | SINE | Alu | Name=AluJb |
| ADediting_780803 | chr19_53116718_- | SINE | Alu | Name=AluJb |
| ADediting_780804 | chr19_53117358_- | SINE | Alu | Name=AluSp |
| ADediting_780805 | chr19_53117378_- | SINE | Alu | Name=AluSp |
| ADediting_780806 | chr19_53117402_- | SINE | Alu | Name=AluSp |
| ADediting_780807 | chr19_53121322_- | SINE | Alu | Name=AluSx3 |
| ADediting_780808 | chr19_53121506_- | SINE | Alu | Name=AluSz |
| ADediting_780809 | chr19_53121512_- | SINE | Alu | Name=AluSz |
| ADediting_780810 | chr19_53121552_- | SINE | Alu | Name=AluSz |
| ADediting_780811 | chr19_53121592_- | SINE | Alu | Name=AluSz |
| ADediting_780812 | chr19_53121650_- | SINE | Alu | Name=AluSz |
| ADediting_780813 | chr19_53121668_- | SINE | Alu | Name=AluSz |
| ADediting_780814 | chr19_53121697_- | SINE | Alu | Name=AluSz |
| ADediting_780815 | chr19_53122002_- | SINE | Alu | Name=AluSp |
| ADediting_780816 | chr19_53122021_- | SINE | Alu | Name=AluSp |
| ADediting_780817 | chr19_53123981_- | SINE | Alu | Name=AluSq |
| ADediting_780823 | chr19_53125181_- | SINE | Alu | Name=AluSc |
| ADediting_780824 | chr19_53125208_- | SINE | Alu | Name=AluSc |
| ADediting_780825 | chr19_53125217_- | SINE | Alu | Name=AluSc |
| ADediting_780826 | chr19_53125367_- | SINE | Alu | Name=AluJb |
| ADediting_780827 | chr19_53125403_- | SINE | Alu | Name=AluJb |
| ADediting_780828 | chr19_53125458_- | SINE | Alu | Name=AluJb |
| ADediting_780829 | chr19_53125473_- | SINE | Alu | Name=AluJb |
| ADediting_780830 | chr19_53125514_- | SINE | Alu | Name=AluJb |
| ADediting_780831 | chr19_53125537_- | SINE | Alu | Name=AluJb |
| ADediting_780832 | chr19_53125546_- | SINE | Alu | Name=AluJb |
| ADediting_780833 | chr19_53125735_- | SINE | Alu | Name=AluSg |
| ADediting_780835 | chr19_53125750_- | SINE | Alu | Name=AluSg |
| ADediting_780836 | chr19_53125755_- | SINE | Alu | Name=AluSg |
| ADediting_780837 | chr19_53125772_- | SINE | Alu | Name=AluSg |
| ADediting_780838 | chr19_53125775_- | SINE | Alu | Name=AluSg |
| ADediting_780840 | chr19_53125789_- | SINE | Alu | Name=AluSg |
| ADediting_780841 | chr19_53125816_- | SINE | Alu | Name=AluSg |
| ADediting_780842 | chr19_53125886_- | SINE | Alu | Name=AluSg |
| ADediting_780843 | chr19_53125922_- | SINE | Alu | Name=AluSg |
| ADediting_780844 | chr19_53127644_- | SINE | Alu | Name=AluSc |
| ADediting_780845 | chr19_53127755_- | SINE | Alu | Name=AluSc |
| ADediting_780846 | chr19_53127765_- | SINE | Alu | Name=AluSc |
| ADediting_780847 | chr19_53129828_- | SINE | Alu | Name=AluSz |
| ADediting_780848 | chr19_53129891_- | SINE | Alu | Name=AluSz |
| ADediting_780849 | chr19_53129894_- | SINE | Alu | Name=AluSz |
| ADediting_780850 | chr19_53129943_- | SINE | Alu | Name=AluSz |
| ADediting_780851 | chr19_53129953_- | SINE | Alu | Name=AluSz |
| ADediting_780852 | chr19_53130018_- | SINE | Alu | Name=AluSz |
| ADediting_780853 | chr19_53130778_- | SINE | Alu | Name=AluSg7 |
| ADediting_780854 | chr19_53130783_- | SINE | Alu | Name=AluSg7 |
| ADediting_780855 | chr19_53130784_- | SINE | Alu | Name=AluSg7 |
| ADediting_780856 | chr19_53130802_- | SINE | Alu | Name=AluSg7 |
| ADediting_780857 | chr19_53130819_- | SINE | Alu | Name=AluSg7 |
| ADediting_780858 | chr19_53130916_- | SINE | Alu | Name=AluSg7 |
| ADediting_780859 | chr19_53130925_- | SINE | Alu | Name=AluSg7 |
| ADediting_1558748 | chr19_53115213_- | SINE | Alu | Name=AluSq2 |
| ADediting_1558749 | chr19_53120829_- | SINE | Alu | Name=AluSg |
| ADediting_1558750 | chr19_53125513_- | SINE | Alu | Name=AluJb |
| ADediting_1558751 | chr19_53127777_- | SINE | Alu | Name=AluSc |
| ADediting_1558752 | chr19_53130849_- | SINE | Alu | Name=AluSg7 |
| ADediting_1631664 | chr19_53116731_- | SINE | Alu | Name=AluJb |
| ADediting_1631665 | chr19_53116732_- | SINE | Alu | Name=AluJb |
| ADediting_1631666 | chr19_53116736_- | SINE | Alu | Name=AluJb |
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RNA A-to-I editing events in the alternative splicing sites for ZNF415 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ZNF415 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for ZNF415 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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Top |
The effects of the RNA editing to the miRNA binding sites for ZNF415 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_780800 | chr19_53115272_- | ENSG00000170954.11 | ENST00000602110.5 | ZNF415-226 | hsa-miR-17-3p | chr19 | 53115272 | 53115278 | 7mer-m8 | 53115271 | 53115292 | 150 | -18.24 |
| ADediting_780801 | chr19_53115288_- | ENSG00000170954.11 | ENST00000602110.5 | ZNF415-226 | hsa-miR-3130-3p | chr19 | 53115288 | 53115294 | 7mer-m8 | 53115287 | 53115308 | 146 | -18.92 |
| ADediting_780801 | chr19_53115288_- | ENSG00000170954.11 | ENST00000602110.5 | ZNF415-226 | hsa-miR-873-3p | chr19 | 53115284 | 53115290 | 7mer-m8 | 53115283 | 53115305 | 145 | -15.62 |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_780800 | chr19_53115272_- | ENSG00000170954.11 | ENST00000602110.5 | ZNF415-226 | hsa-miR-6516-5p | chr19 | 53115272 | 53115278 | 7mer-m8 | 53115271 | 53115293 | 144 | -14.25 |
| ADediting_780801 | chr19_53115288_- | ENSG00000170954.11 | ENST00000602110.5 | ZNF415-226 | hsa-miR-32-5p | chr19 | 53115287 | 53115293 | 7mer-m8 | 53115286 | 53115308 | 148 | -12.8 |
| ADediting_780801 | chr19_53115288_- | ENSG00000170954.11 | ENST00000602110.5 | ZNF415-226 | hsa-miR-363-3p | chr19 | 53115287 | 53115293 | 7mer-m8 | 53115286 | 53115312 | 149 | -19.28 |
| ADediting_780801 | chr19_53115288_- | ENSG00000170954.11 | ENST00000602110.5 | ZNF415-226 | hsa-miR-5186 | chr19 | 53115284 | 53115290 | 7mer-m8 | 53115283 | 53115303 | 140 | -9.9 |
| ADediting_780801 | chr19_53115288_- | ENSG00000170954.11 | ENST00000602110.5 | ZNF415-226 | hsa-miR-92a-3p | chr19 | 53115287 | 53115293 | 7mer-m8 | 53115286 | 53115311 | 161 | -26.35 |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_843620 | chr2_207754818_+ | ENSG00000170954.11 | ENST00000594011.5 | ZNF415-204 | hsa-miR-4775 | chr19 | 53109273 | 53109280 | 8mer-1a | 53109273 | 53109294 | 151 | -10.58 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000170954.11 | ENST00000595193.5 | ZNF415-207 | hsa-miR-4775 | chr19 | 53109273 | 53109280 | 8mer-1a | 53109273 | 53109294 | 151 | -10.58 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000170954.11 | ENST00000597503.5 | ZNF415-213 | hsa-miR-4775 | chr19 | 53109273 | 53109280 | 8mer-1a | 53109273 | 53109294 | 151 | -10.58 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000170954.11 | ENST00000597748.5 | ZNF415-214 | hsa-miR-4775 | chr19 | 53109273 | 53109280 | 8mer-1a | 53109273 | 53109294 | 151 | -10.58 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1535951 | chr14_100874558_+ | ENSG00000170954.11 | ENST00000594011.5 | ZNF415-204 | hsa-miR-337-3p | chr19 | 53109651 | 53109658 | 8mer-1a | 53109651 | 53109672 | 147 | -13.11 |
| ADediting_1535951 | chr14_100874558_+ | ENSG00000170954.11 | ENST00000595193.5 | ZNF415-207 | hsa-miR-337-3p | chr19 | 53109651 | 53109658 | 8mer-1a | 53109651 | 53109672 | 147 | -13.11 |
| ADediting_1535951 | chr14_100874558_+ | ENSG00000170954.11 | ENST00000597503.5 | ZNF415-213 | hsa-miR-337-3p | chr19 | 53109651 | 53109658 | 8mer-1a | 53109651 | 53109672 | 147 | -13.11 |
| ADediting_1535951 | chr14_100874558_+ | ENSG00000170954.11 | ENST00000597748.5 | ZNF415-214 | hsa-miR-337-3p | chr19 | 53109651 | 53109658 | 8mer-1a | 53109651 | 53109672 | 147 | -13.11 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000170954.11 | ENST00000594011.5 | ZNF415-204 | hsa-miR-4775 | chr19 | 53108377 | 53108383 | 7mer-1a | 53108377 | 53108398 | 141 | -9.09 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000170954.11 | ENST00000595193.5 | ZNF415-207 | hsa-miR-4775 | chr19 | 53108377 | 53108383 | 7mer-1a | 53108377 | 53108398 | 141 | -9.09 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000170954.11 | ENST00000597503.5 | ZNF415-213 | hsa-miR-4775 | chr19 | 53108377 | 53108383 | 7mer-1a | 53108377 | 53108398 | 141 | -9.09 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000170954.11 | ENST00000597748.5 | ZNF415-214 | hsa-miR-4775 | chr19 | 53108377 | 53108383 | 7mer-1a | 53108377 | 53108398 | 141 | -9.09 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for ZNF415 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000597503.5 | protein_coding |  |  |
| ENST00000595193.5 | protein_coding |  |  |
| ENST00000594011.5 | protein_coding |  |  |
| ENST00000597748.5 | protein_coding |  |  |
| ENST00000595813.5 | protein_coding |  |  |
| ENST00000599261.5 | protein_coding |  |  |
| ENST00000602110.5 | lncRNA |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_1558748 | ENST00000597503.5 | chr19_53115213_- | 436 | -623.50 | -623.50 | -629.70 |
| ADediting_780799 | ENST00000597503.5 | chr19_53115235_- | 414 | -626.50 | -623.50 | -629.70 |
| ADediting_780800 | ENST00000597503.5 | chr19_53115272_- | 377 | -624.10 | -623.50 | -629.70 |
| ADediting_780801 | ENST00000597503.5 | chr19_53115288_- | 361 | -626.10 | -623.50 | -629.70 |
| ADediting_1558748 | ENST00000595193.5 | chr19_53115213_- | 446 | -616.20 | -613.10 | -618.60 |
| ADediting_780799 | ENST00000595193.5 | chr19_53115235_- | 424 | -615.50 | -613.10 | -618.60 |
| ADediting_780800 | ENST00000595193.5 | chr19_53115272_- | 387 | -615.60 | -613.10 | -618.60 |
| ADediting_780801 | ENST00000595193.5 | chr19_53115288_- | 371 | -616.30 | -613.10 | -618.60 |
| ADediting_1558748 | ENST00000594011.5 | chr19_53115213_- | 598 | -675.90 | -672.80 | -678.10 |
| ADediting_780799 | ENST00000594011.5 | chr19_53115235_- | 576 | -674.50 | -672.80 | -678.10 |
| ADediting_780800 | ENST00000594011.5 | chr19_53115272_- | 539 | -675.30 | -672.80 | -678.10 |
| ADediting_780801 | ENST00000594011.5 | chr19_53115288_- | 523 | -676.00 | -672.80 | -678.10 |
| ADediting_1558748 | ENST00000597748.5 | chr19_53115213_- | 447 | -621.60 | -619.30 | -626.10 |
| ADediting_780799 | ENST00000597748.5 | chr19_53115235_- | 425 | -621.50 | -619.30 | -626.10 |
| ADediting_780800 | ENST00000597748.5 | chr19_53115272_- | 388 | -621.70 | -619.30 | -626.10 |
| ADediting_780801 | ENST00000597748.5 | chr19_53115288_- | 372 | -621.80 | -619.30 | -626.10 |
| ADediting_1558748 | ENST00000595813.5 | chr19_53115213_- | 474 | -177.30 | -176.60 | -181.00 |
| ADediting_780799 | ENST00000595813.5 | chr19_53115235_- | 452 | -177.70 | -176.60 | -181.00 |
| ADediting_780800 | ENST00000595813.5 | chr19_53115272_- | 415 | -177.40 | -176.60 | -181.00 |
| ADediting_780801 | ENST00000595813.5 | chr19_53115288_- | 399 | -180.20 | -176.60 | -181.00 |
| ADediting_1558748 | ENST00000599261.5 | chr19_53115213_- | 566 | -186.40 | -183.80 | -192.40 |
| ADediting_780799 | ENST00000599261.5 | chr19_53115235_- | 544 | -187.30 | -183.80 | -192.40 |
| ADediting_780800 | ENST00000599261.5 | chr19_53115272_- | 507 | -186.30 | -183.80 | -192.40 |
| ADediting_780801 | ENST00000599261.5 | chr19_53115288_- | 491 | -187.60 | -183.80 | -192.40 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_780800 | ENST00000602110.5 | chr19_53115272_- | 531 | -164.80 | -164.20 | -167.40 |
| ADediting_780801 | ENST00000602110.5 | chr19_53115288_- | 515 | -166.80 | -164.20 | -167.40 |
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Relation with ADAR for ZNF415 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_780790 | chr19_53111435_- | 0.0182445461858256 | -0.134010126712496 | 0.000289595940816217 | -0.204500430168814 | 5.3886945503883e-08 | 0.30279919884523 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 1.6111566740133e-65 | 0.78317554686106 | 8.19619053980982e-55 | 0.739195325999795 | 0.0740651624500186 | 0.101597718841165 |
| AC | 9.68054731571366e-81 | 0.87659075213159 | 7.25086475398814e-53 | 0.782141387355468 | 1.5031170112329e-16 | 0.490647187361798 |
| PCC | 6.70212595632292e-34 | 0.736355923648496 | 2.39775831284183e-31 | 0.716220603030105 | 0.0014020596808631 | 0.22953897977044 |
| CER | 4.79277469683125e-45 | 0.859799674298785 | 7.72199478546474e-26 | 0.725994045953371 | 0.00400063283725234 | 0.233688955486507 |
| TCX | 1.75523264870973e-18 | 0.6375192045802 | 0.00945960151214208 | 0.211249826626557 | 1.34986572102867e-15 | 0.592688854116201 |
| FP | 3.30043511295803e-27 | 0.696934463664983 | 3.17091757231362e-27 | 0.697101274031989 | 0.0144962587791725 | 0.182979265424154 |
| IFG | 1.02866535933464e-06 | 0.808151349048714 | 0.00176266637893658 | 0.593524145556797 | 0.191067293418719 | 0.270426592509536 |
| PG | 1.1469350307776e-48 | 0.830635411643944 | 2.72453187177027e-26 | 0.677039964812948 | 0.591515195113045 | 0.0395999880832927 |
| STG | 6.10509724237649e-19 | 0.787801759533973 | 1.15607779827702e-13 | 0.700822787865871 | 0.0209937453049939 | 0.251539343831844 |
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Relation with AD stages for ZNF415 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 1.56043817742201e-05 | 0.402639582728089 |
| TCX | 6.93904683227382e-06 | 0.421152207073447 |
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RelatedDrugs for ZNF415 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ZNF415 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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