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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for SMPD4 |
 Gene summary |
| Gene information | Gene symbol | SMPD4 | Gene ID | 55627 |
| Gene name | sphingomyelin phosphodiesterase 4 | |
| Synonyms | NEDMABA|NEDMEBA|NET13|NSMASE-3|NSMASE3|SKNY | |
| Cytomap | 2q21.1 | |
| Type of gene | protein-coding | |
| Description | sphingomyelin phosphodiesterase 4neutral sphingomyelinase 3neutral sphingomyelinase IIIsphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) | |
| Modification date | 20200327 | |
| UniProtAcc | Q9NXE4, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| SMPD4 | GO:0006685 | sphingomyelin catabolic process | 16517606 |
| SMPD4 | GO:0046475 | glycerophospholipid catabolic process | 16517606 |
| SMPD4 | GO:0046513 | ceramide biosynthetic process | 16517606 |
| SMPD4 | GO:0071356 | cellular response to tumor necrosis factor | 16517606 |
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RNA A-to-I events for SMPD4 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_810673(130152066, -), ADediting_810674(130157896, -), ADediting_810675(130157897, -), ADediting_810676(130157941, -), ADediting_810677(130157966, -), ADediting_810678(130158000, -), ADediting_810679(130158008, -), ADediting_810680(130158016, -), ADediting_810681(130158021, -), ADediting_810682(130158024, -), ADediting_810683(130158031, -), ADediting_810684(130158058, -), ADediting_810685(130158071, -), ADediting_810686(130158072, -), ADediting_810687(130158078, -), ADediting_810688(130158088, -), ADediting_810689(130158096, -), ADediting_810690(130158118, -), ADediting_810691(130158385, -), ADediting_810692(130158390, -), ADediting_810693(130158394, -), ADediting_810694(130158413, -), ADediting_810695(130158414, -), ADediting_810696(130158428, -), ADediting_810697(130158438, -), ADediting_810698(130158441, -), ADediting_810699(130158449, -), ADediting_810700(130158461, -), ADediting_810701(130158465, -), ADediting_810702(130158473, -), ADediting_810703(130158481, -), ADediting_810704(130158484, -), ADediting_810705(130158485, -), ADediting_810706(130158486, -), ADediting_810707(130158487, -), ADediting_810708(130158491, -), ADediting_810709(130158492, -), ADediting_810710(130158503, -), ADediting_810711(130158508, -), ADediting_810712(130158516, -), ADediting_810713(130158552, -), ADediting_810714(130158560, -), ADediting_810715(130159010, -), ADediting_810716(130159027, -), ADediting_810717(130159029, -), ADediting_810718(130159033, -), ADediting_810719(130159035, -), ADediting_810720(130159078, -), ADediting_810721(130159080, -), ADediting_810722(130159084, -), ADediting_810723(130159092, -), ADediting_810724(130159093, -), ADediting_810725(130159110, -), ADediting_810726(130159123, -), ADediting_810727(130159127, -), ADediting_810728(130159161, -), ADediting_810729(130159164, -), ADediting_810730(130159165, -), ADediting_810731(130159166, -), ADediting_810732(130159167, -), ADediting_810733(130159170, -), ADediting_810734(130159173, -), ADediting_810735(130159176, -), ADediting_810736(130159188, -), ADediting_810737(130159196, -), ADediting_810738(130159208, -), ADediting_810739(130159211, -), ADediting_810740(130159213, -), ADediting_810741(130159219, -), ADediting_810742(130159222, -), ADediting_810743(130159227, -), ADediting_810744(130159241, -), ADediting_810745(130159262, -), ADediting_810746(130159267, -), ADediting_810747(130159268, -), ADediting_810748(130159382, -), ADediting_810749(130159394, -), ADediting_810750(130159395, -), ADediting_810751(130159421, -), ADediting_810752(130159422, -), ADediting_810753(130159447, -), ADediting_810754(130159454, -), ADediting_810755(130159459, -), ADediting_810756(130159473, -), ADediting_810757(130159482, -), ADediting_810758(130159490, -), ADediting_810759(130159491, -), ADediting_810760(130159510, -), ADediting_810761(130159514, -), ADediting_810762(130159516, -), ADediting_810763(130159526, -), ADediting_810764(130159529, -), ADediting_810765(130159538, -), ADediting_810766(130159555, -), ADediting_810767(130159556, -), ADediting_810768(130159562, -), ADediting_810769(130159569, -), ADediting_810770(130159575, -), ADediting_810771(130159594, -), ADediting_810772(130159596, -), ADediting_810773(130159612, -), ADediting_810774(130159624, -), ADediting_810775(130159636, -), ADediting_810776(130165768, -), ADediting_810777(130166065, -), ADediting_810778(130166077, -), ADediting_810779(130166129, -), ADediting_810780(130166146, -), ADediting_810781(130166161, -), ADediting_810782(130166187, -), ADediting_810783(130166193, -), ADediting_810784(130166197, -), ADediting_810785(130166227, -), ADediting_810786(130166233, -), ADediting_810787(130166246, -), ADediting_810788(130166262, -), ADediting_810789(130166263, -), ADediting_810790(130167153, -), ADediting_810791(130167213, -), ADediting_810792(130167253, -), ADediting_810793(130167258, -), ADediting_810794(130167269, -), ADediting_810795(130167285, -), ADediting_810796(130167289, -), ADediting_810797(130167294, -), ADediting_810798(130167363, -), ADediting_810799(130167371, -), ADediting_810800(130167397, -), ADediting_810801(130168562, -), ADediting_810802(130168695, -), ADediting_810803(130168784, -), ADediting_810804(130168845, -), ADediting_810805(130168850, -), ADediting_810806(130168854, -), ADediting_810807(130168859, -), ADediting_810808(130168860, -), ADediting_810809(130169775, -), ADediting_810810(130169803, -), ADediting_810811(130170663, -), ADediting_810812(130170840, -), ADediting_810813(130170844, -), ADediting_810814(130170856, -), ADediting_810815(130170858, -), ADediting_810816(130170869, -), ADediting_810817(130170898, -), ADediting_810818(130170939, -), ADediting_810819(130170961, -), ADediting_810820(130170966, -), ADediting_810821(130170978, -), ADediting_810822(130171201, -), ADediting_810823(130171242, -), ADediting_810824(130171281, -), ADediting_810825(130171282, -), ADediting_810826(130171283, -), ADediting_810827(130171284, -), ADediting_810828(130171311, -), ADediting_810829(130171326, -), ADediting_810830(130171395, -), ADediting_810831(130177633, -), ADediting_810832(130177639, -), ADediting_810833(130178702, -), ADediting_810834(130179737, -), ADediting_810835(130179792, -), ADediting_810836(130179793, -), ADediting_1560816(130158083, -), ADediting_1560817(130158131, -), ADediting_1560818(130158463, -), ADediting_1560819(130159116, -), ADediting_1560820(130159499, -), ADediting_1560821(130159604, -), ADediting_1560822(130165849, -), ADediting_1560823(130166152, -), ADediting_1560824(130166160, -), ADediting_1560825(130166594, -), ADediting_1560826(130167395, -), ADediting_1632717(130168084, -), ADediting_1632718(130168090, -), ADediting_1632719(130168094, -), ADediting_1632720(130168276, -), |
Top |
RNA editing positional annotations for SMPD4 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_810673 | chr2_130152066_- | UTR3 |
| ADediting_810674 | chr2_130157896_- | intronic |
| ADediting_810675 | chr2_130157897_- | intronic |
| ADediting_810676 | chr2_130157941_- | intronic |
| ADediting_810677 | chr2_130157966_- | intronic |
| ADediting_810678 | chr2_130158000_- | intronic |
| ADediting_810679 | chr2_130158008_- | intronic |
| ADediting_810680 | chr2_130158016_- | intronic |
| ADediting_810681 | chr2_130158021_- | intronic |
| ADediting_810682 | chr2_130158024_- | intronic |
| ADediting_810683 | chr2_130158031_- | intronic |
| ADediting_810684 | chr2_130158058_- | intronic |
| ADediting_810685 | chr2_130158071_- | intronic |
| ADediting_810686 | chr2_130158072_- | intronic |
| ADediting_810687 | chr2_130158078_- | intronic |
| ADediting_810688 | chr2_130158088_- | intronic |
| ADediting_810689 | chr2_130158096_- | intronic |
| ADediting_810690 | chr2_130158118_- | intronic |
| ADediting_810691 | chr2_130158385_- | intronic |
| ADediting_810692 | chr2_130158390_- | intronic |
| ADediting_810693 | chr2_130158394_- | intronic |
| ADediting_810694 | chr2_130158413_- | intronic |
| ADediting_810695 | chr2_130158414_- | intronic |
| ADediting_810696 | chr2_130158428_- | intronic |
| ADediting_810697 | chr2_130158438_- | intronic |
| ADediting_810698 | chr2_130158441_- | intronic |
| ADediting_810699 | chr2_130158449_- | intronic |
| ADediting_810700 | chr2_130158461_- | intronic |
| ADediting_810701 | chr2_130158465_- | intronic |
| ADediting_810702 | chr2_130158473_- | intronic |
| ADediting_810703 | chr2_130158481_- | intronic |
| ADediting_810704 | chr2_130158484_- | intronic |
| ADediting_810705 | chr2_130158485_- | intronic |
| ADediting_810706 | chr2_130158486_- | intronic |
| ADediting_810707 | chr2_130158487_- | intronic |
| ADediting_810708 | chr2_130158491_- | intronic |
| ADediting_810709 | chr2_130158492_- | intronic |
| ADediting_810710 | chr2_130158503_- | intronic |
| ADediting_810711 | chr2_130158508_- | intronic |
| ADediting_810712 | chr2_130158516_- | intronic |
| ADediting_810713 | chr2_130158552_- | intronic |
| ADediting_810714 | chr2_130158560_- | intronic |
| ADediting_810715 | chr2_130159010_- | intronic |
| ADediting_810716 | chr2_130159027_- | intronic |
| ADediting_810717 | chr2_130159029_- | intronic |
| ADediting_810718 | chr2_130159033_- | intronic |
| ADediting_810719 | chr2_130159035_- | intronic |
| ADediting_810720 | chr2_130159078_- | intronic |
| ADediting_810721 | chr2_130159080_- | intronic |
| ADediting_810722 | chr2_130159084_- | intronic |
| ADediting_810723 | chr2_130159092_- | intronic |
| ADediting_810724 | chr2_130159093_- | intronic |
| ADediting_810725 | chr2_130159110_- | intronic |
| ADediting_810726 | chr2_130159123_- | intronic |
| ADediting_810727 | chr2_130159127_- | intronic |
| ADediting_810728 | chr2_130159161_- | intronic |
| ADediting_810729 | chr2_130159164_- | intronic |
| ADediting_810730 | chr2_130159165_- | intronic |
| ADediting_810731 | chr2_130159166_- | intronic |
| ADediting_810732 | chr2_130159167_- | intronic |
| ADediting_810733 | chr2_130159170_- | intronic |
| ADediting_810734 | chr2_130159173_- | intronic |
| ADediting_810735 | chr2_130159176_- | intronic |
| ADediting_810736 | chr2_130159188_- | intronic |
| ADediting_810737 | chr2_130159196_- | intronic |
| ADediting_810738 | chr2_130159208_- | intronic |
| ADediting_810739 | chr2_130159211_- | intronic |
| ADediting_810740 | chr2_130159213_- | intronic |
| ADediting_810741 | chr2_130159219_- | intronic |
| ADediting_810742 | chr2_130159222_- | intronic |
| ADediting_810743 | chr2_130159227_- | intronic |
| ADediting_810744 | chr2_130159241_- | intronic |
| ADediting_810745 | chr2_130159262_- | intronic |
| ADediting_810746 | chr2_130159267_- | intronic |
| ADediting_810747 | chr2_130159268_- | intronic |
| ADediting_810748 | chr2_130159382_- | intronic |
| ADediting_810749 | chr2_130159394_- | intronic |
| ADediting_810750 | chr2_130159395_- | intronic |
| ADediting_810751 | chr2_130159421_- | intronic |
| ADediting_810752 | chr2_130159422_- | intronic |
| ADediting_810753 | chr2_130159447_- | intronic |
| ADediting_810754 | chr2_130159454_- | intronic |
| ADediting_810755 | chr2_130159459_- | intronic |
| ADediting_810756 | chr2_130159473_- | intronic |
| ADediting_810757 | chr2_130159482_- | intronic |
| ADediting_810758 | chr2_130159490_- | intronic |
| ADediting_810759 | chr2_130159491_- | intronic |
| ADediting_810760 | chr2_130159510_- | intronic |
| ADediting_810761 | chr2_130159514_- | UTR3 |
| ADediting_810762 | chr2_130159516_- | UTR3 |
| ADediting_810763 | chr2_130159526_- | UTR3 |
| ADediting_810764 | chr2_130159529_- | UTR3 |
| ADediting_810765 | chr2_130159538_- | UTR3 |
| ADediting_810766 | chr2_130159555_- | UTR3 |
| ADediting_810767 | chr2_130159556_- | UTR3 |
| ADediting_810768 | chr2_130159562_- | UTR3 |
| ADediting_810769 | chr2_130159569_- | UTR3 |
| ADediting_810770 | chr2_130159575_- | UTR3 |
| ADediting_810771 | chr2_130159594_- | UTR3 |
| ADediting_810772 | chr2_130159596_- | UTR3 |
| ADediting_810773 | chr2_130159612_- | UTR3 |
| ADediting_810774 | chr2_130159624_- | UTR3 |
| ADediting_810775 | chr2_130159636_- | splicing |
| ADediting_810776 | chr2_130165768_- | intronic |
| ADediting_810777 | chr2_130166065_- | intronic |
| ADediting_810778 | chr2_130166077_- | intronic |
| ADediting_810779 | chr2_130166129_- | intronic |
| ADediting_810780 | chr2_130166146_- | intronic |
| ADediting_810781 | chr2_130166161_- | intronic |
| ADediting_810782 | chr2_130166187_- | intronic |
| ADediting_810783 | chr2_130166193_- | intronic |
| ADediting_810784 | chr2_130166197_- | intronic |
| ADediting_810785 | chr2_130166227_- | intronic |
| ADediting_810786 | chr2_130166233_- | intronic |
| ADediting_810787 | chr2_130166246_- | intronic |
| ADediting_810788 | chr2_130166262_- | intronic |
| ADediting_810789 | chr2_130166263_- | intronic |
| ADediting_810790 | chr2_130167153_- | intronic |
| ADediting_810791 | chr2_130167213_- | intronic |
| ADediting_810792 | chr2_130167253_- | intronic |
| ADediting_810793 | chr2_130167258_- | intronic |
| ADediting_810794 | chr2_130167269_- | intronic |
| ADediting_810795 | chr2_130167285_- | intronic |
| ADediting_810796 | chr2_130167289_- | intronic |
| ADediting_810797 | chr2_130167294_- | intronic |
| ADediting_810798 | chr2_130167363_- | intronic |
| ADediting_810799 | chr2_130167371_- | intronic |
| ADediting_810800 | chr2_130167397_- | intronic |
| ADediting_810801 | chr2_130168562_- | intronic |
| ADediting_810802 | chr2_130168695_- | intronic |
| ADediting_810803 | chr2_130168784_- | intronic |
| ADediting_810804 | chr2_130168845_- | intronic |
| ADediting_810805 | chr2_130168850_- | intronic |
| ADediting_810806 | chr2_130168854_- | intronic |
| ADediting_810807 | chr2_130168859_- | intronic |
| ADediting_810808 | chr2_130168860_- | intronic |
| ADediting_810809 | chr2_130169775_- | intronic |
| ADediting_810810 | chr2_130169803_- | intronic |
| ADediting_810811 | chr2_130170663_- | intronic |
| ADediting_810812 | chr2_130170840_- | intronic |
| ADediting_810813 | chr2_130170844_- | intronic |
| ADediting_810814 | chr2_130170856_- | intronic |
| ADediting_810815 | chr2_130170858_- | intronic |
| ADediting_810816 | chr2_130170869_- | intronic |
| ADediting_810817 | chr2_130170898_- | intronic |
| ADediting_810818 | chr2_130170939_- | intronic |
| ADediting_810819 | chr2_130170961_- | intronic |
| ADediting_810820 | chr2_130170966_- | intronic |
| ADediting_810821 | chr2_130170978_- | intronic |
| ADediting_810822 | chr2_130171201_- | intronic |
| ADediting_810823 | chr2_130171242_- | intronic |
| ADediting_810824 | chr2_130171281_- | intronic |
| ADediting_810825 | chr2_130171282_- | intronic |
| ADediting_810826 | chr2_130171283_- | intronic |
| ADediting_810827 | chr2_130171284_- | intronic |
| ADediting_810828 | chr2_130171311_- | intronic |
| ADediting_810829 | chr2_130171326_- | intronic |
| ADediting_810830 | chr2_130171395_- | intronic |
| ADediting_810831 | chr2_130177633_- | intronic |
| ADediting_810832 | chr2_130177639_- | intronic |
| ADediting_810833 | chr2_130178702_- | intronic |
| ADediting_810834 | chr2_130179737_- | intronic |
| ADediting_810835 | chr2_130179792_- | intronic |
| ADediting_810836 | chr2_130179793_- | intronic |
| ADediting_1560816 | chr2_130158083_- | intronic |
| ADediting_1560817 | chr2_130158131_- | intronic |
| ADediting_1560818 | chr2_130158463_- | intronic |
| ADediting_1560819 | chr2_130159116_- | intronic |
| ADediting_1560820 | chr2_130159499_- | intronic |
| ADediting_1560821 | chr2_130159604_- | UTR3 |
| ADediting_1560822 | chr2_130165849_- | intronic |
| ADediting_1560823 | chr2_130166152_- | intronic |
| ADediting_1560824 | chr2_130166160_- | intronic |
| ADediting_1560825 | chr2_130166594_- | intronic |
| ADediting_1560826 | chr2_130167395_- | intronic |
| ADediting_1632717 | chr2_130168084_- | intronic |
| ADediting_1632718 | chr2_130168090_- | intronic |
| ADediting_1632719 | chr2_130168094_- | intronic |
| ADediting_1632720 | chr2_130168276_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_810674 | chr2_130157896_- | SINE | Alu | Name=AluJr |
| ADediting_810675 | chr2_130157897_- | SINE | Alu | Name=AluJr |
| ADediting_810676 | chr2_130157941_- | SINE | Alu | Name=AluJr |
| ADediting_810677 | chr2_130157966_- | SINE | Alu | Name=AluJr |
| ADediting_810678 | chr2_130158000_- | SINE | Alu | Name=AluJr |
| ADediting_810679 | chr2_130158008_- | SINE | Alu | Name=AluJr |
| ADediting_810680 | chr2_130158016_- | SINE | Alu | Name=AluJr |
| ADediting_810681 | chr2_130158021_- | SINE | Alu | Name=AluJr |
| ADediting_810682 | chr2_130158024_- | SINE | Alu | Name=AluJr |
| ADediting_810683 | chr2_130158031_- | SINE | Alu | Name=AluJr |
| ADediting_810684 | chr2_130158058_- | SINE | Alu | Name=AluJr |
| ADediting_810685 | chr2_130158071_- | SINE | Alu | Name=AluJr |
| ADediting_810686 | chr2_130158072_- | SINE | Alu | Name=AluJr |
| ADediting_810687 | chr2_130158078_- | SINE | Alu | Name=AluJr |
| ADediting_810688 | chr2_130158088_- | SINE | Alu | Name=AluJr |
| ADediting_810689 | chr2_130158096_- | SINE | Alu | Name=AluJr |
| ADediting_810690 | chr2_130158118_- | SINE | Alu | Name=AluJr |
| ADediting_810691 | chr2_130158385_- | SINE | Alu | Name=AluSx |
| ADediting_810692 | chr2_130158390_- | SINE | Alu | Name=AluSx |
| ADediting_810693 | chr2_130158394_- | SINE | Alu | Name=AluSx |
| ADediting_810694 | chr2_130158413_- | SINE | Alu | Name=AluSx |
| ADediting_810695 | chr2_130158414_- | SINE | Alu | Name=AluSx |
| ADediting_810696 | chr2_130158428_- | SINE | Alu | Name=AluSx |
| ADediting_810697 | chr2_130158438_- | SINE | Alu | Name=AluSx |
| ADediting_810698 | chr2_130158441_- | SINE | Alu | Name=AluSx |
| ADediting_810699 | chr2_130158449_- | SINE | Alu | Name=AluSx |
| ADediting_810700 | chr2_130158461_- | SINE | Alu | Name=AluSx |
| ADediting_810701 | chr2_130158465_- | SINE | Alu | Name=AluSx |
| ADediting_810702 | chr2_130158473_- | SINE | Alu | Name=AluSx |
| ADediting_810703 | chr2_130158481_- | SINE | Alu | Name=AluSx |
| ADediting_810704 | chr2_130158484_- | SINE | Alu | Name=AluSx |
| ADediting_810705 | chr2_130158485_- | SINE | Alu | Name=AluSx |
| ADediting_810706 | chr2_130158486_- | SINE | Alu | Name=AluSx |
| ADediting_810707 | chr2_130158487_- | SINE | Alu | Name=AluSx |
| ADediting_810708 | chr2_130158491_- | SINE | Alu | Name=AluSx |
| ADediting_810709 | chr2_130158492_- | SINE | Alu | Name=AluSx |
| ADediting_810710 | chr2_130158503_- | SINE | Alu | Name=AluSx |
| ADediting_810711 | chr2_130158508_- | SINE | Alu | Name=AluSx |
| ADediting_810712 | chr2_130158516_- | SINE | Alu | Name=AluSx |
| ADediting_810713 | chr2_130158552_- | SINE | Alu | Name=AluSx |
| ADediting_810714 | chr2_130158560_- | SINE | Alu | Name=AluSx |
| ADediting_810715 | chr2_130159010_- | SINE | Alu | Name=AluJb |
| ADediting_810716 | chr2_130159027_- | SINE | Alu | Name=AluJb |
| ADediting_810717 | chr2_130159029_- | SINE | Alu | Name=AluJb |
| ADediting_810718 | chr2_130159033_- | SINE | Alu | Name=AluJb |
| ADediting_810719 | chr2_130159035_- | SINE | Alu | Name=AluJb |
| ADediting_810720 | chr2_130159078_- | SINE | Alu | Name=AluJb |
| ADediting_810721 | chr2_130159080_- | SINE | Alu | Name=AluJb |
| ADediting_810722 | chr2_130159084_- | SINE | Alu | Name=AluJb |
| ADediting_810723 | chr2_130159092_- | SINE | Alu | Name=AluJb |
| ADediting_810724 | chr2_130159093_- | SINE | Alu | Name=AluJb |
| ADediting_810725 | chr2_130159110_- | SINE | Alu | Name=AluJb |
| ADediting_810726 | chr2_130159123_- | SINE | Alu | Name=AluJb |
| ADediting_810727 | chr2_130159127_- | SINE | Alu | Name=AluJb |
| ADediting_810728 | chr2_130159161_- | SINE | Alu | Name=AluJb |
| ADediting_810729 | chr2_130159164_- | SINE | Alu | Name=AluJb |
| ADediting_810730 | chr2_130159165_- | SINE | Alu | Name=AluJb |
| ADediting_810731 | chr2_130159166_- | SINE | Alu | Name=AluJb |
| ADediting_810732 | chr2_130159167_- | SINE | Alu | Name=AluJb |
| ADediting_810733 | chr2_130159170_- | SINE | Alu | Name=AluJb |
| ADediting_810734 | chr2_130159173_- | SINE | Alu | Name=AluJb |
| ADediting_810735 | chr2_130159176_- | SINE | Alu | Name=AluJb |
| ADediting_810736 | chr2_130159188_- | SINE | Alu | Name=AluJb |
| ADediting_810737 | chr2_130159196_- | SINE | Alu | Name=AluJb |
| ADediting_810738 | chr2_130159208_- | SINE | Alu | Name=AluJb |
| ADediting_810739 | chr2_130159211_- | SINE | Alu | Name=AluJb |
| ADediting_810740 | chr2_130159213_- | SINE | Alu | Name=AluJb |
| ADediting_810741 | chr2_130159219_- | SINE | Alu | Name=AluJb |
| ADediting_810742 | chr2_130159222_- | SINE | Alu | Name=AluJb |
| ADediting_810743 | chr2_130159227_- | SINE | Alu | Name=AluJb |
| ADediting_810744 | chr2_130159241_- | SINE | Alu | Name=AluJb |
| ADediting_810745 | chr2_130159262_- | SINE | Alu | Name=AluJb |
| ADediting_810746 | chr2_130159267_- | SINE | Alu | Name=AluJb |
| ADediting_810747 | chr2_130159268_- | SINE | Alu | Name=AluJb |
| ADediting_810748 | chr2_130159382_- | SINE | Alu | Name=AluSz |
| ADediting_810749 | chr2_130159394_- | SINE | Alu | Name=AluSz |
| ADediting_810750 | chr2_130159395_- | SINE | Alu | Name=AluSz |
| ADediting_810751 | chr2_130159421_- | SINE | Alu | Name=AluSz |
| ADediting_810752 | chr2_130159422_- | SINE | Alu | Name=AluSz |
| ADediting_810753 | chr2_130159447_- | SINE | Alu | Name=AluSz |
| ADediting_810754 | chr2_130159454_- | SINE | Alu | Name=AluSz |
| ADediting_810755 | chr2_130159459_- | SINE | Alu | Name=AluSz |
| ADediting_810756 | chr2_130159473_- | SINE | Alu | Name=AluSz |
| ADediting_810757 | chr2_130159482_- | SINE | Alu | Name=AluSz |
| ADediting_810758 | chr2_130159490_- | SINE | Alu | Name=AluSz |
| ADediting_810759 | chr2_130159491_- | SINE | Alu | Name=AluSz |
| ADediting_810760 | chr2_130159510_- | SINE | Alu | Name=AluSz |
| ADediting_810761 | chr2_130159514_- | SINE | Alu | Name=AluSz |
| ADediting_810762 | chr2_130159516_- | SINE | Alu | Name=AluSz |
| ADediting_810763 | chr2_130159526_- | SINE | Alu | Name=AluSz |
| ADediting_810764 | chr2_130159529_- | SINE | Alu | Name=AluSz |
| ADediting_810765 | chr2_130159538_- | SINE | Alu | Name=AluSz |
| ADediting_810766 | chr2_130159555_- | SINE | Alu | Name=AluSz |
| ADediting_810767 | chr2_130159556_- | SINE | Alu | Name=AluSz |
| ADediting_810768 | chr2_130159562_- | SINE | Alu | Name=AluSz |
| ADediting_810769 | chr2_130159569_- | SINE | Alu | Name=AluSz |
| ADediting_810770 | chr2_130159575_- | SINE | Alu | Name=AluSz |
| ADediting_810771 | chr2_130159594_- | SINE | Alu | Name=AluSz |
| ADediting_810772 | chr2_130159596_- | SINE | Alu | Name=AluSz |
| ADediting_810773 | chr2_130159612_- | SINE | Alu | Name=AluSz |
| ADediting_810774 | chr2_130159624_- | SINE | Alu | Name=AluSz |
| ADediting_810775 | chr2_130159636_- | SINE | Alu | Name=AluSz |
| ADediting_810776 | chr2_130165768_- | SINE | Alu | Name=AluJr4 |
| ADediting_810777 | chr2_130166065_- | SINE | Alu | Name=AluSx1 |
| ADediting_810778 | chr2_130166077_- | SINE | Alu | Name=AluSx1 |
| ADediting_810779 | chr2_130166129_- | SINE | Alu | Name=AluSx1 |
| ADediting_810780 | chr2_130166146_- | SINE | Alu | Name=AluSx1 |
| ADediting_810781 | chr2_130166161_- | SINE | Alu | Name=AluSx1 |
| ADediting_810782 | chr2_130166187_- | SINE | Alu | Name=AluSx1 |
| ADediting_810783 | chr2_130166193_- | SINE | Alu | Name=AluSx1 |
| ADediting_810784 | chr2_130166197_- | SINE | Alu | Name=AluSx1 |
| ADediting_810785 | chr2_130166227_- | SINE | Alu | Name=AluSx1 |
| ADediting_810786 | chr2_130166233_- | SINE | Alu | Name=AluSx1 |
| ADediting_810787 | chr2_130166246_- | SINE | Alu | Name=AluSx1 |
| ADediting_810788 | chr2_130166262_- | SINE | Alu | Name=AluSx1 |
| ADediting_810789 | chr2_130166263_- | SINE | Alu | Name=AluSx1 |
| ADediting_810790 | chr2_130167153_- | SINE | Alu | Name=AluSx1 |
| ADediting_810791 | chr2_130167213_- | SINE | Alu | Name=AluSx1 |
| ADediting_810792 | chr2_130167253_- | SINE | Alu | Name=AluSx1 |
| ADediting_810793 | chr2_130167258_- | SINE | Alu | Name=AluSx1 |
| ADediting_810794 | chr2_130167269_- | SINE | Alu | Name=AluSx1 |
| ADediting_810795 | chr2_130167285_- | SINE | Alu | Name=AluSx1 |
| ADediting_810796 | chr2_130167289_- | SINE | Alu | Name=AluSx1 |
| ADediting_810797 | chr2_130167294_- | SINE | Alu | Name=AluSx1 |
| ADediting_810798 | chr2_130167363_- | SINE | Alu | Name=AluSx1 |
| ADediting_810799 | chr2_130167371_- | SINE | Alu | Name=AluSx1 |
| ADediting_810800 | chr2_130167397_- | SINE | Alu | Name=AluSx1 |
| ADediting_810801 | chr2_130168562_- | SINE | Alu | Name=AluJo |
| ADediting_810802 | chr2_130168695_- | SINE | Alu | Name=AluJo |
| ADediting_810803 | chr2_130168784_- | SINE | Alu | Name=AluSz6 |
| ADediting_810804 | chr2_130168845_- | SINE | Alu | Name=AluSz6 |
| ADediting_810805 | chr2_130168850_- | SINE | Alu | Name=AluSz6 |
| ADediting_810806 | chr2_130168854_- | SINE | Alu | Name=AluSz6 |
| ADediting_810807 | chr2_130168859_- | SINE | Alu | Name=AluSz6 |
| ADediting_810808 | chr2_130168860_- | SINE | Alu | Name=AluSz6 |
| ADediting_810809 | chr2_130169775_- | SINE | Alu | Name=AluJr |
| ADediting_810810 | chr2_130169803_- | SINE | Alu | Name=AluJr |
| ADediting_810811 | chr2_130170663_- | SINE | Alu | Name=AluJr |
| ADediting_810812 | chr2_130170840_- | SINE | Alu | Name=AluSx |
| ADediting_810813 | chr2_130170844_- | SINE | Alu | Name=AluSx |
| ADediting_810814 | chr2_130170856_- | SINE | Alu | Name=AluSx |
| ADediting_810815 | chr2_130170858_- | SINE | Alu | Name=AluSx |
| ADediting_810816 | chr2_130170869_- | SINE | Alu | Name=AluSx |
| ADediting_810817 | chr2_130170898_- | SINE | Alu | Name=AluSx |
| ADediting_810818 | chr2_130170939_- | SINE | Alu | Name=AluSx |
| ADediting_810819 | chr2_130170961_- | SINE | Alu | Name=AluSx |
| ADediting_810820 | chr2_130170966_- | SINE | Alu | Name=AluSx |
| ADediting_810821 | chr2_130170978_- | SINE | Alu | Name=AluSx |
| ADediting_810822 | chr2_130171201_- | SINE | Alu | Name=AluSx |
| ADediting_810823 | chr2_130171242_- | SINE | Alu | Name=AluSx |
| ADediting_810824 | chr2_130171281_- | SINE | Alu | Name=AluSx |
| ADediting_810825 | chr2_130171282_- | SINE | Alu | Name=AluSx |
| ADediting_810826 | chr2_130171283_- | SINE | Alu | Name=AluSx |
| ADediting_810827 | chr2_130171284_- | SINE | Alu | Name=AluSx |
| ADediting_810828 | chr2_130171311_- | SINE | Alu | Name=AluSx |
| ADediting_810829 | chr2_130171326_- | SINE | Alu | Name=AluSx |
| ADediting_810830 | chr2_130171395_- | SINE | Alu | Name=AluSx |
| ADediting_810831 | chr2_130177633_- | SINE | Alu | Name=AluSx1 |
| ADediting_810832 | chr2_130177639_- | SINE | Alu | Name=AluSx1 |
| ADediting_810833 | chr2_130178702_- | SINE | Alu | Name=AluSz6 |
| ADediting_810834 | chr2_130179737_- | SINE | Alu | Name=AluSc5 |
| ADediting_810835 | chr2_130179792_- | SINE | Alu | Name=AluSc5 |
| ADediting_810836 | chr2_130179793_- | SINE | Alu | Name=AluSc5 |
| ADediting_1560816 | chr2_130158083_- | SINE | Alu | Name=AluJr |
| ADediting_1560817 | chr2_130158131_- | SINE | Alu | Name=AluJr |
| ADediting_1560818 | chr2_130158463_- | SINE | Alu | Name=AluSx |
| ADediting_1560819 | chr2_130159116_- | SINE | Alu | Name=AluJb |
| ADediting_1560820 | chr2_130159499_- | SINE | Alu | Name=AluSz |
| ADediting_1560821 | chr2_130159604_- | SINE | Alu | Name=AluSz |
| ADediting_1560822 | chr2_130165849_- | SINE | Alu | Name=AluJr4 |
| ADediting_1560823 | chr2_130166152_- | SINE | Alu | Name=AluSx1 |
| ADediting_1560824 | chr2_130166160_- | SINE | Alu | Name=AluSx1 |
| ADediting_1560826 | chr2_130167395_- | SINE | Alu | Name=AluSx1 |
| ADediting_1632717 | chr2_130168084_- | SINE | Alu | Name=AluJr |
| ADediting_1632718 | chr2_130168090_- | SINE | Alu | Name=AluJr |
| ADediting_1632719 | chr2_130168094_- | SINE | Alu | Name=AluJr |
| ADediting_1632720 | chr2_130168276_- | SINE | Alu | Name=AluJb |
Top |
RNA A-to-I editing events in the alternative splicing sites for SMPD4 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| A5SS | ADediting_810719 | chr2_130159035_- | 130159035:130159043 | 5ss | 6i | CGGGTGACA | 1.24 | CGGGTGACG | 3.42 |
| ES | ADediting_810775 | chr2_130159636_- | 130159632:130159654 | 3ss | 2i | TTTTTTTTTTTTTTTTTGAGATG | 4.74 | TTTTTTTTTTTTTTTTTGGGATG | -3.21 |
| ES | ADediting_810775 | chr2_130159636_- | 130159632:130159654 | 3ss | 2i | TTTTTTTTTTTTTTTTTGAGATG | 4.74 | TTTTTTTTTTTTTTTTTGGGATG | -3.21 |
| ES | ADediting_810760 | chr2_130159510_- | 130159507:130159515 | 5ss | 3i | CAGGCATGT | 2.05 | CAGGCGTGT | -0.76 |
| ES | ADediting_810761 | chr2_130159514_- | 130159507:130159515 | 5ss | 2e | CAGGCATGT | 2.05 | CGGGCATGT | 1.03 |
| ME1 | ADediting_810775 | chr2_130159636_- | 130159632:130159654 | 3ss | 2i | TTTTTTTTTTTTTTTTTGAGATG | 4.74 | TTTTTTTTTTTTTTTTTGGGATG | -3.21 |
| ME1 | ADediting_810760 | chr2_130159510_- | 130159507:130159515 | 5ss | 3i | CAGGCATGT | 2.05 | CAGGCGTGT | -0.76 |
| ME1 | ADediting_810761 | chr2_130159514_- | 130159507:130159515 | 5ss | 2e | CAGGCATGT | 2.05 | CGGGCATGT | 1.03 |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for SMPD4 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for SMPD4 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for SMPD4 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_810673 | chr2_130152066_- | ENSG00000136699.19 | ENST00000351288.10 | SMPD4-201 | hsa-miR-508-5p | chr2 | 130152062 | 130152068 | 7mer-m8 | 130152061 | 130152083 | 152 | -16.04 |
| ADediting_810673 | chr2_130152066_- | ENSG00000136699.19 | ENST00000351288.10 | SMPD4-201 | hsa-miR-9902 | chr2 | 130152064 | 130152071 | 8mer-1a | 130152064 | 130152086 | 149 | -14.04 |
| ADediting_810673 | chr2_130152066_- | ENSG00000136699.19 | ENST00000409031.5 | SMPD4-202 | hsa-miR-508-5p | chr2 | 130152062 | 130152068 | 7mer-m8 | 130152061 | 130152083 | 152 | -16.04 |
| ADediting_810673 | chr2_130152066_- | ENSG00000136699.19 | ENST00000409031.5 | SMPD4-202 | hsa-miR-9902 | chr2 | 130152064 | 130152071 | 8mer-1a | 130152064 | 130152086 | 149 | -14.04 |
| ADediting_810673 | chr2_130152066_- | ENSG00000136699.19 | ENST00000431183.6 | SMPD4-205 | hsa-miR-508-5p | chr2 | 130152062 | 130152068 | 7mer-m8 | 130152061 | 130152083 | 152 | -16.04 |
| ADediting_810673 | chr2_130152066_- | ENSG00000136699.19 | ENST00000431183.6 | SMPD4-205 | hsa-miR-9902 | chr2 | 130152064 | 130152071 | 8mer-1a | 130152064 | 130152086 | 149 | -14.04 |
| ADediting_810673 | chr2_130152066_- | ENSG00000136699.19 | ENST00000439886.5 | SMPD4-209 | hsa-miR-508-5p | chr2 | 130152062 | 130152068 | 7mer-m8 | 130152061 | 130152083 | 152 | -16.04 |
| ADediting_810673 | chr2_130152066_- | ENSG00000136699.19 | ENST00000439886.5 | SMPD4-209 | hsa-miR-9902 | chr2 | 130152064 | 130152071 | 8mer-1a | 130152064 | 130152086 | 149 | -14.04 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_810673 | chr2_130152066_- | ENSG00000136699.19 | ENST00000351288.10 | SMPD4-201 | hsa-miR-517-5p | chr2 | 130152063 | 130152069 | 7mer-m8 | 130152062 | 130152083 | 140 | -10.04 |
| ADediting_810673 | chr2_130152066_- | ENSG00000136699.19 | ENST00000351288.10 | SMPD4-201 | hsa-miR-5684 | chr2 | 130152062 | 130152068 | 7mer-m8 | 130152061 | 130152080 | 140 | -12.77 |
| ADediting_810673 | chr2_130152066_- | ENSG00000136699.19 | ENST00000351288.10 | SMPD4-201 | hsa-miR-618 | chr2 | 130152061 | 130152067 | 7mer-m8 | 130152060 | 130152085 | 144 | -10.27 |
| ADediting_810673 | chr2_130152066_- | ENSG00000136699.19 | ENST00000351288.10 | SMPD4-201 | hsa-miR-6508-5p | chr2 | 130152064 | 130152071 | 8mer-1a | 130152064 | 130152084 | 141 | -12.32 |
| ADediting_810673 | chr2_130152066_- | ENSG00000136699.19 | ENST00000409031.5 | SMPD4-202 | hsa-miR-517-5p | chr2 | 130152063 | 130152069 | 7mer-m8 | 130152062 | 130152083 | 140 | -10.04 |
| ADediting_810673 | chr2_130152066_- | ENSG00000136699.19 | ENST00000409031.5 | SMPD4-202 | hsa-miR-5684 | chr2 | 130152062 | 130152068 | 7mer-m8 | 130152061 | 130152080 | 140 | -12.77 |
| ADediting_810673 | chr2_130152066_- | ENSG00000136699.19 | ENST00000409031.5 | SMPD4-202 | hsa-miR-618 | chr2 | 130152061 | 130152067 | 7mer-m8 | 130152060 | 130152085 | 144 | -10.27 |
| ADediting_810673 | chr2_130152066_- | ENSG00000136699.19 | ENST00000409031.5 | SMPD4-202 | hsa-miR-6508-5p | chr2 | 130152064 | 130152071 | 8mer-1a | 130152064 | 130152084 | 141 | -12.32 |
| ADediting_810673 | chr2_130152066_- | ENSG00000136699.19 | ENST00000431183.6 | SMPD4-205 | hsa-miR-517-5p | chr2 | 130152063 | 130152069 | 7mer-m8 | 130152062 | 130152083 | 140 | -10.04 |
| ADediting_810673 | chr2_130152066_- | ENSG00000136699.19 | ENST00000431183.6 | SMPD4-205 | hsa-miR-5684 | chr2 | 130152062 | 130152068 | 7mer-m8 | 130152061 | 130152080 | 140 | -12.77 |
| ADediting_810673 | chr2_130152066_- | ENSG00000136699.19 | ENST00000431183.6 | SMPD4-205 | hsa-miR-618 | chr2 | 130152061 | 130152067 | 7mer-m8 | 130152060 | 130152085 | 144 | -10.27 |
| ADediting_810673 | chr2_130152066_- | ENSG00000136699.19 | ENST00000431183.6 | SMPD4-205 | hsa-miR-6508-5p | chr2 | 130152064 | 130152071 | 8mer-1a | 130152064 | 130152084 | 141 | -12.32 |
| ADediting_810673 | chr2_130152066_- | ENSG00000136699.19 | ENST00000439886.5 | SMPD4-209 | hsa-miR-517-5p | chr2 | 130152063 | 130152069 | 7mer-m8 | 130152062 | 130152083 | 140 | -10.04 |
| ADediting_810673 | chr2_130152066_- | ENSG00000136699.19 | ENST00000439886.5 | SMPD4-209 | hsa-miR-5684 | chr2 | 130152062 | 130152068 | 7mer-m8 | 130152061 | 130152080 | 140 | -12.77 |
| ADediting_810673 | chr2_130152066_- | ENSG00000136699.19 | ENST00000439886.5 | SMPD4-209 | hsa-miR-618 | chr2 | 130152061 | 130152067 | 7mer-m8 | 130152060 | 130152085 | 144 | -10.27 |
| ADediting_810673 | chr2_130152066_- | ENSG00000136699.19 | ENST00000439886.5 | SMPD4-209 | hsa-miR-6508-5p | chr2 | 130152064 | 130152071 | 8mer-1a | 130152064 | 130152084 | 141 | -12.32 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337757 | chr7_5495852_- | ENSG00000136699.19 | ENST00000351288.10 | SMPD4-201 | hsa-miR-589-3p | chr2 | 130151778 | 130151784 | 7mer-m8 | 130151777 | 130151800 | 153 | -17.27 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000136699.19 | ENST00000409031.5 | SMPD4-202 | hsa-miR-589-3p | chr2 | 130151778 | 130151784 | 7mer-m8 | 130151777 | 130151800 | 153 | -17.27 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000136699.19 | ENST00000431183.6 | SMPD4-205 | hsa-miR-589-3p | chr2 | 130151778 | 130151784 | 7mer-m8 | 130151777 | 130151800 | 153 | -17.27 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000136699.19 | ENST00000439886.5 | SMPD4-209 | hsa-miR-589-3p | chr2 | 130151778 | 130151784 | 7mer-m8 | 130151777 | 130151800 | 153 | -17.27 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000136699.19 | ENST00000351288.10 | SMPD4-201 | hsa-miR-641 | chr2 | 130151417 | 130151423 | 7mer-m8 | 130151416 | 130151442 | 142 | -15.54 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000136699.19 | ENST00000409031.5 | SMPD4-202 | hsa-miR-641 | chr2 | 130151417 | 130151423 | 7mer-m8 | 130151416 | 130151442 | 142 | -15.54 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000136699.19 | ENST00000431183.6 | SMPD4-205 | hsa-miR-641 | chr2 | 130151417 | 130151423 | 7mer-m8 | 130151416 | 130151442 | 142 | -15.54 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000136699.19 | ENST00000439886.5 | SMPD4-209 | hsa-miR-641 | chr2 | 130151417 | 130151423 | 7mer-m8 | 130151416 | 130151442 | 142 | -15.54 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| Differentially expressed gene-miRNA network |
Top |
The effects of the RNA editing to the stability of the RNA structures for SMPD4 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000431183.6 | protein_coding |  |  |
| ENST00000351288.10 | protein_coding |  |  |
| ENST00000439886.5 | protein_coding |  |  |
| ENST00000409031.5 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_810673 | ENST00000431183.6 | chr2_130152066_- | 2940 | -1402.50 | -1395.90 | -1402.50 |
| ADediting_810673 | ENST00000351288.10 | chr2_130152066_- | 3003 | -1409.80 | -1403.20 | -1409.80 |
| ADediting_810673 | ENST00000439886.5 | chr2_130152066_- | 2714 | -1307.10 | -1300.50 | -1307.10 |
| ADediting_810673 | ENST00000409031.5 | chr2_130152066_- | 4239 | -2025.40 | -2018.80 | -2025.40 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
Top |
Relation with ADAR for SMPD4 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_810674 | chr2_130157896_- | 5.73286312259471e-15 | 0.424156824846472 | 3.98327476688423e-13 | 0.396690946184842 | 0.00223356138307395 | 0.173029226374533 |
| CER | ADediting_810674 | chr2_130157896_- | 3.09376439378908e-08 | 0.433133685275939 | 2.39482149729687e-07 | 0.406798405834505 | 0.992608088583937 | -0.000762826170168612 |
| TCX | ADediting_810674 | chr2_130157896_- | 0.000256779741215343 | 0.294287075896476 | 1.7833075193921e-05 | 0.342520944566356 | 0.327706629512989 | -0.08045750903315 |
| DLPFC | ADediting_810677 | chr2_130157966_- | 5.85649252113305e-11 | 0.360727351585537 | 1.28082946143357e-10 | 0.354661289552183 | 0.00574374377936316 | 0.156538750920432 |
| CER | ADediting_810677 | chr2_130157966_- | 1.3142961777101e-13 | 0.557162204693482 | 1.45895113838841e-14 | 0.574753750163754 | 0.0854062798238416 | 0.140926266943334 |
| TCX | ADediting_810677 | chr2_130157966_- | 0.00196182507302867 | 0.25082792362311 | 0.000162159193436943 | 0.30321007778605 | 0.652892236490779 | 0.0370188495547493 |
| CER | ADediting_810678 | chr2_130158000_- | 1.81330244557065e-08 | 0.43965430408708 | 8.28531609574771e-12 | 0.520911524092257 | 0.211710902535515 | 0.102559031818187 |
| DLPFC | ADediting_810679 | chr2_130158008_- | 6.0669727614919e-08 | 0.301676003453349 | 2.06916100552003e-06 | 0.265794970354167 | 0.000964222672145155 | 0.186575653529149 |
| CER | ADediting_810679 | chr2_130158008_- | 4.2612195307179e-12 | 0.527027510619402 | 1.70378495011199e-15 | 0.590982282824028 | 0.0391518912647012 | 0.16861230728677 |
| DLPFC | ADediting_810682 | chr2_130158024_- | 1.00514271334598e-13 | 0.405887643676253 | 3.4947054933325e-11 | 0.364660606472713 | 3.78200542289847e-05 | 0.231765551956427 |
| CER | ADediting_810682 | chr2_130158024_- | 8.77847829556803e-11 | 0.498161187456667 | 1.07190807231559e-09 | 0.47206228659493 | 0.0086878625740767 | 0.213565546572285 |
| TCX | ADediting_810682 | chr2_130158024_- | 0.168219165948424 | 0.113093807473387 | 0.832196061702044 | 0.017445029439353 | 1.82871312017808e-05 | 0.342102156750676 |
| DLPFC | ADediting_810684 | chr2_130158058_- | 3.13106585328194e-11 | 0.365490777783713 | 2.36647615835346e-10 | 0.34981075873809 | 0.000574085684148508 | 0.194496417283395 |
| CER | ADediting_810684 | chr2_130158058_- | 3.95122313321315e-08 | 0.430101327703373 | 1.11547543578506e-06 | 0.385395056177492 | 0.657984331553599 | 0.0364389441352355 |
| CER | ADediting_810685 | chr2_130158071_- | 4.37018393485774e-06 | 0.365042678620039 | 3.91333474039548e-10 | 0.482837353291936 | 0.350209117675571 | 0.0768055531172735 |
| CER | ADediting_810686 | chr2_130158072_- | 0.00571773103287389 | 0.224630496174602 | 3.3124284765221e-05 | 0.332027452872578 | 0.134400997382252 | 0.122791290254021 |
| CER | ADediting_810687 | chr2_130158078_- | 0.000142669582535427 | 0.305645556577878 | 0.000216696829301719 | 0.297615507316126 | 0.0367318039606931 | 0.17071838730861 |
| DLPFC | ADediting_810688 | chr2_130158088_- | 3.0249755184353e-14 | 0.413682979904614 | 1.113041952133e-15 | 0.434134728222221 | 0.0337709735642453 | 0.120613461195291 |
| CER | ADediting_810688 | chr2_130158088_- | 1.06583216226632e-11 | 0.518562700382346 | 8.63750669311156e-15 | 0.578798823272594 | 0.0012163962938114 | 0.261707390854388 |
| TCX | ADediting_810688 | chr2_130158088_- | 0.126059387488308 | 0.12546536354817 | 9.87640094925827e-06 | 0.352194777270196 | 0.131915034099435 | -0.123574562142739 |
| DLPFC | ADediting_810689 | chr2_130158096_- | 3.01741746553453e-12 | 0.382626897651209 | 1.55272982398544e-08 | 0.314310963321802 | 2.02758484942912e-06 | 0.266016553430675 |
| CER | ADediting_810689 | chr2_130158096_- | 3.64001851001593e-12 | 0.528459047960335 | 1.40894917336164e-11 | 0.515938734476957 | 0.000188614773135815 | 0.300307876241011 |
| TCX | ADediting_810689 | chr2_130158096_- | 0.0285686820068045 | 0.178815271895662 | 0.545392306249434 | 0.0497574813668187 | 2.21848244232892e-05 | 0.338863720854191 |
| CER | ADediting_810691 | chr2_130158385_- | 3.79446584760411e-11 | 0.506439167716433 | 5.21881176665082e-13 | 0.545573703963003 | 0.000112614723500389 | 0.310089845947878 |
| TCX | ADediting_810691 | chr2_130158385_- | 0.0831982713843654 | 0.141922086170648 | 3.74710301204456e-06 | 0.36740552197241 | 0.520069482075611 | -0.0529261105450408 |
| CER | ADediting_810694 | chr2_130158413_- | 6.05344824608706e-08 | 0.424741234112782 | 1.34401815267326e-08 | 0.443250535475453 | 0.0689623574625461 | 0.148910150598072 |
| CER | ADediting_810695 | chr2_130158414_- | 2.83287124078108e-08 | 0.434218454005252 | 1.18052942415711e-07 | 0.416157556097491 | 0.810848094204577 | 0.0197043206639414 |
| CER | ADediting_810696 | chr2_130158428_- | 0.000479037503616563 | 0.281697735969851 | 1.73128353861898e-05 | 0.343013318195009 | 0.189901225029793 | 0.107621355147853 |
| CER | ADediting_810698 | chr2_130158441_- | 2.78079525700725e-06 | 0.371934321963561 | 0.000829180668760167 | 0.270111768263156 | 0.0212680269410368 | 0.187948018641241 |
| CER | ADediting_810699 | chr2_130158449_- | 5.79902318662424e-08 | 0.425284967973521 | 1.91782112509315e-07 | 0.409768173376164 | 0.0115270573774689 | 0.205780571849487 |
| TCX | ADediting_810699 | chr2_130158449_- | 0.00212627577032777 | 0.248949353906021 | 0.703465495920188 | 0.031334155597226 | 1.45552602976817e-05 | 0.345882081970955 |
| CER | ADediting_810701 | chr2_130158465_- | 9.96658238582295e-05 | 0.312357427941689 | 5.62406938610688e-08 | 0.425672303873801 | 0.00101497811149377 | 0.265711194407342 |
| CER | ADediting_810702 | chr2_130158473_- | 1.97613000840278e-05 | 0.340807021079698 | 2.06884774162269e-10 | 0.489465058867552 | 0.000960083701859357 | 0.266928746184028 |
| TCX | ADediting_810702 | chr2_130158473_- | 0.480239452549432 | 0.0580750739521094 | 4.09451912558951e-05 | 0.328346087295702 | 0.640244911866396 | -0.0384671567007167 |
| CER | ADediting_810703 | chr2_130158481_- | 3.55869881532466e-08 | 0.431401895020718 | 2.19776398941113e-10 | 0.488842555960949 | 0.0128946941458606 | 0.202619723116886 |
| TCX | ADediting_810703 | chr2_130158481_- | 0.00107196930618 | 0.264509374793828 | 0.183644638169138 | 0.109151174207487 | 0.000100790438167243 | 0.312149888555497 |
| CER | ADediting_810704 | chr2_130158484_- | 1.05566398156511e-06 | 0.386188294383678 | 7.60189794593552e-07 | 0.39087198017558 | 0.0153387695733415 | 0.197638440976737 |
| TCX | ADediting_810704 | chr2_130158484_- | 0.000943913618659356 | 0.267299571608541 | 0.501382112461341 | 0.0553151134415537 | 6.63727675415063e-06 | 0.358527154515308 |
| CER | ADediting_810705 | chr2_130158485_- | 2.78257993602787e-11 | 0.509444900149284 | 1.77012320506446e-09 | 0.466555724404823 | 0.00244725939557606 | 0.245634427784058 |
| TCX | ADediting_810705 | chr2_130158485_- | 0.00162067073434637 | 0.255231510758006 | 0.391974494484882 | 0.0703976841741278 | 2.43337847706056e-05 | 0.337301188939574 |
| CER | ADediting_810706 | chr2_130158486_- | 5.33054110632911e-06 | 0.361963307724888 | 0.00260232372288653 | 0.24417212573605 | 0.741126325247833 | -0.0271964783276303 |
| CER | ADediting_810710 | chr2_130158503_- | 2.40884541056e-11 | 0.510832680353476 | 1.1743982773511e-14 | 0.57643475318269 | 0.0675738920214737 | 0.14965264979945 |
| TCX | ADediting_810710 | chr2_130158503_- | 0.173485473269155 | 0.111718827931801 | 0.000106403782333349 | 0.311145279207727 | 0.182634798779122 | -0.109401655608894 |
| CER | ADediting_810711 | chr2_130158508_- | 0.000413762119997857 | 0.284708158978481 | 8.38162084190083e-07 | 0.389486729394951 | 0.193828614384593 | 0.106679755587889 |
| CER | ADediting_810717 | chr2_130159029_- | 0.00104785099412452 | 0.265010658666129 | 2.15324430981805e-05 | 0.339366360389225 | 0.201991089195895 | 0.10476622768304 |
| DLPFC | ADediting_810719 | chr2_130159035_- | 1.0289081397639e-10 | 0.356371977323778 | 2.05373633065616e-09 | 0.332042968029985 | 0.000323422114619747 | 0.202917589951134 |
| CER | ADediting_810719 | chr2_130159035_- | 3.54568264236014e-08 | 0.431447343446743 | 7.04023633080174e-09 | 0.450875712427308 | 0.00843387772483599 | 0.2143675464407 |
| TCX | ADediting_810719 | chr2_130159035_- | 5.75824622614155e-07 | 0.394778424949466 | 0.00244185599904435 | 0.24568688127527 | 6.12953686771528e-05 | 0.321205553428546 |
| DLPFC | ADediting_810721 | chr2_130159080_- | 7.70800260486305e-09 | 0.320580565915696 | 2.07943276261214e-09 | 0.331937389593718 | 0.00118395836695301 | 0.183350882948701 |
| CER | ADediting_810721 | chr2_130159080_- | 9.62869054340599e-07 | 0.387508001226671 | 8.32500195018865e-08 | 0.420676131365334 | 0.00976772640266348 | 0.210371644090656 |
| TCX | ADediting_810721 | chr2_130159080_- | 3.13873857316803e-06 | 0.370103939466148 | 0.0278033221116983 | 0.179671956877271 | 8.73798868505891e-06 | 0.354160519961119 |
| CER | ADediting_810723 | chr2_130159092_- | 1.44221782685925e-05 | 0.346033180407489 | 0.000212849682997861 | 0.29796447237977 | 0.0605478102289844 | 0.153612951427401 |
| TCX | ADediting_810723 | chr2_130159092_- | 9.57517350487687e-06 | 0.352693189557754 | 0.0239916631725419 | 0.184265073148934 | 0.000765456597039155 | 0.271832144934854 |
| CER | ADediting_810726 | chr2_130159123_- | 1.20495798940738e-07 | 0.415890522753815 | 2.33147477074276e-12 | 0.532470471788285 | 0.00163957439637313 | 0.254966344598452 |
| TCX | ADediting_810726 | chr2_130159123_- | 4.75897923402934e-06 | 0.363725397643864 | 0.00212375247917419 | 0.248977166293584 | 0.000288971142348031 | 0.291946776175487 |
| TCX | ADediting_810727 | chr2_130159127_- | 0.000116242350609735 | 0.309498276187031 | 0.175406764893701 | 0.111224892277466 | 0.000191853076672136 | 0.299979059245262 |
| CER | ADediting_810728 | chr2_130159161_- | 1.68953977369037e-07 | 0.411449836082286 | 4.37892921022287e-12 | 0.526779265535839 | 0.0032549372442848 | 0.238772622189954 |
| TCX | ADediting_810728 | chr2_130159161_- | 9.27591864491463e-06 | 0.353203239835481 | 0.00243748310760039 | 0.245729408163825 | 0.000442795020350005 | 0.283318673567766 |
| CER | ADediting_810729 | chr2_130159164_- | 0.000203887762033137 | 0.298800681792969 | 1.05588864370799e-06 | 0.386185235529048 | 0.0813702742981237 | 0.142762681466231 |
| CER | ADediting_810730 | chr2_130159165_- | 2.82218774478279e-07 | 0.404584334563397 | 2.7024200351508e-09 | 0.461833940114352 | 7.85046853817708e-05 | 0.316736037843071 |
| TCX | ADediting_810730 | chr2_130159165_- | 0.00740333827697702 | 0.217858324439033 | 0.426772324935772 | 0.0653665713286363 | 0.000168576276916484 | 0.30246768083697 |
| CER | ADediting_810731 | chr2_130159166_- | 0.000165488000694933 | 0.302821618506479 | 1.73850969295273e-07 | 0.411071508291382 | 0.0152441765949487 | 0.197817870968817 |
| TCX | ADediting_810731 | chr2_130159166_- | 0.322357259822703 | 0.0813490837983362 | 0.114900381630246 | -0.129265004892947 | 8.82891415564377e-06 | 0.353994865048483 |
| CER | ADediting_810733 | chr2_130159170_- | 2.23399347220616e-06 | 0.375215963211481 | 2.21729110171585e-07 | 0.407831468273829 | 0.0193729081266504 | 0.190758642096988 |
| TCX | ADediting_810733 | chr2_130159170_- | 0.000375589898637643 | 0.286679088279179 | 0.104198098635398 | 0.133189506932419 | 5.09204763118552e-07 | 0.396491742618685 |
| TCX | ADediting_810734 | chr2_130159173_- | 0.0135148528800859 | 0.201282359693277 | 0.921405830653657 | 0.00812362713064426 | 1.4997030216789e-05 | 0.34538968906168 |
| CER | ADediting_810735 | chr2_130159176_- | 3.40411361717623e-09 | 0.459227223511905 | 3.29411965923695e-06 | 0.369370401513387 | 0.0284760244669979 | 0.17891793669891 |
| TCX | ADediting_810735 | chr2_130159176_- | 0.000253509077586315 | 0.294539886441849 | 0.187475078447943 | 0.108210142768205 | 4.07417895193818e-06 | 0.366122347470332 |
| CER | ADediting_810737 | chr2_130159196_- | 1.6291924463106e-07 | 0.411930767102962 | 4.15595308458417e-06 | 0.36581682667407 | 0.552120275630088 | 0.0489279542021412 |
| CER | ADediting_810738 | chr2_130159208_- | 5.17296177760261e-09 | 0.454445285363391 | 3.43633959732584e-11 | 0.507403068544865 | 0.000106320324407395 | 0.311159849296722 |
| TCX | ADediting_810739 | chr2_130159211_- | 0.141218973782263 | 0.120698502397196 | 0.55772192687933 | -0.0482410397424927 | 1.8910127601338e-05 | 0.341543230284326 |
| CER | ADediting_810740 | chr2_130159213_- | 0.000195143905859043 | 0.299650155869868 | 6.60035994848625e-05 | 0.319876226700193 | 0.779633318332249 | -0.0230349889931589 |
| TCX | ADediting_810740 | chr2_130159213_- | 0.0604483464125932 | 0.153671658978673 | 0.775038348160905 | -0.0235283161750867 | 6.72382934925692e-07 | 0.392604366024163 |
| TCX | ADediting_810741 | chr2_130159219_- | 0.50568402537837 | 0.0547611175401039 | 0.0305535080326008 | -0.176681443741146 | 3.94635703979907e-07 | 0.400013169839494 |
| CER | ADediting_810742 | chr2_130159222_- | 1.64849384728778e-09 | 0.467343169372884 | 2.89735385098889e-10 | 0.485980584891684 | 0.094646825407028 | 0.136969392866956 |
| TCX | ADediting_810742 | chr2_130159222_- | 0.0457568674814419 | 0.163374865888867 | 0.416414231447509 | -0.0668381288616302 | 1.89989779330786e-08 | 0.439090352493997 |
| CER | ADediting_810743 | chr2_130159227_- | 3.25979700562065e-05 | 0.332303722431686 | 3.9220190581402e-06 | 0.366706651873445 | 0.000109766969905119 | 0.310566838993877 |
| TCX | ADediting_810743 | chr2_130159227_- | 0.234447147660218 | 0.0976646300402807 | 0.123131327634286 | -0.126436327786261 | 8.9263775694879e-05 | 0.314388124919491 |
| CER | ADediting_810744 | chr2_130159241_- | 1.63226313657871e-14 | 0.573880272347586 | 3.460959638535e-15 | 0.585725585719267 | 0.0270199400662196 | 0.180569917150234 |
| TCX | ADediting_810744 | chr2_130159241_- | 9.03740001176351e-07 | 0.388413697161982 | 0.000692537332946349 | 0.273970274162096 | 0.084382520113606 | 0.141385389742546 |
| CER | ADediting_810745 | chr2_130159262_- | 3.50954190010887e-05 | 0.33102819469397 | 3.73652742572804e-07 | 0.40076274734009 | 0.000250385246125018 | 0.29478419011626 |
| CER | ADediting_810746 | chr2_130159267_- | 1.25914370161467e-08 | 0.444028340898679 | 6.15056703805034e-12 | 0.523667088262289 | 0.00758397819111386 | 0.217216496098844 |
| CER | ADediting_810748 | chr2_130159382_- | 5.48228633685879e-10 | 0.479273723200875 | 2.00522389973342e-12 | 0.533815999769757 | 0.00051656460590122 | 0.280134549235329 |
| TCX | ADediting_810748 | chr2_130159382_- | 0.339492101616245 | 0.0785256400144261 | 0.000176599630484944 | 0.301575616940118 | 0.900383749686591 | -0.0103065738520312 |
| DLPFC | ADediting_810749 | chr2_130159394_- | 2.54597643411566e-08 | 0.30979499317359 | 8.98301671182926e-08 | 0.297923322925025 | 0.0809301227807218 | 0.0992832379292202 |
| DLPFC | ADediting_810751 | chr2_130159421_- | 5.23350122597032e-07 | 0.280374090308998 | 0.000395325649878757 | 0.200010214764388 | 2.90854817386964e-10 | 0.348162368445267 |
| CER | ADediting_810751 | chr2_130159421_- | 3.85830354220643e-10 | 0.48298616273282 | 2.79849324452843e-09 | 0.461440856812754 | 0.0143513716913793 | 0.199560990643337 |
| TCX | ADediting_810751 | chr2_130159421_- | 0.00419475699475048 | 0.232506260215627 | 0.864717999560717 | 0.0140274348935491 | 2.03159551143379e-08 | 0.438278337655938 |
| TCX | ADediting_810752 | chr2_130159422_- | 0.00448245828113877 | 0.23084082881082 | 0.83729830327468 | 0.0169070336818215 | 1.65123896172701e-05 | 0.343798837131189 |
| CER | ADediting_810753 | chr2_130159447_- | 1.11277492802805e-08 | 0.445496489029798 | 3.8567441296874e-11 | 0.506280592928441 | 0.0025403907095828 | 0.244746456633019 |
| CER | ADediting_810754 | chr2_130159454_- | 3.15871424003743e-10 | 0.485080716572542 | 1.60577145330488e-08 | 0.441118854939176 | 0.00244767665189517 | 0.245630381631269 |
| TCX | ADediting_810754 | chr2_130159454_- | 0.0314011230174752 | 0.175805973251992 | 0.672072323374868 | -0.0348437410096436 | 1.09939420114424e-09 | 0.471786666055026 |
| CER | ADediting_810755 | chr2_130159459_- | 5.01298462042863e-07 | 0.396709112251787 | 6.63801965543041e-06 | 0.358525390229467 | 0.0778420815167819 | 0.144428977695106 |
| TCX | ADediting_810755 | chr2_130159459_- | 0.00309460578723523 | 0.240001735162633 | 0.702979318113452 | -0.031388063713848 | 1.29994232370514e-10 | 0.494208956147254 |
| CER | ADediting_810756 | chr2_130159473_- | 2.25504385401233e-06 | 0.375076125296825 | 0.000169762250821083 | 0.302333362478998 | 0.234366547996433 | 0.0976813756013714 |
| CER | ADediting_810758 | chr2_130159490_- | 1.59249626561685e-05 | 0.34439850591023 | 9.65418232569786e-07 | 0.387470157503687 | 0.70221302657911 | 0.0314730583386217 |
| TCX | ADediting_810758 | chr2_130159490_- | 0.799073451059984 | -0.0209566570804823 | 0.354134981019412 | -0.0761837487899647 | 9.43229224420909e-05 | 0.313374328723742 |
| TCX | ADediting_810759 | chr2_130159491_- | 0.125901449375214 | 0.125517290357512 | 0.418115675572837 | -0.0665949584276752 | 2.76525712849995e-06 | 0.372018755414212 |
| DLPFC | ADediting_810763 | chr2_130159526_- | 4.68862082852226e-08 | 0.304111599340449 | 9.87935903171511e-10 | 0.338187076528232 | 0.0101955111650094 | 0.145725566151962 |
| CER | ADediting_810763 | chr2_130159526_- | 0.00014915026886196 | 0.304803033586989 | 2.01199503715611e-09 | 0.465133933430983 | 8.64661665840102e-05 | 0.314972045832848 |
| FP | ADediting_810763 | chr2_130159526_- | 0.930648274776142 | 0.00656932929884982 | 0.786034901017552 | -0.0204892330220859 | 2.75960791858936e-05 | 0.308702578359846 |
| DLPFC | ADediting_810765 | chr2_130159538_- | 2.60848129369579e-08 | 0.309571535518208 | 1.81941490547054e-14 | 0.416923217241539 | 0.00248827525293248 | 0.171216376167381 |
| CER | ADediting_810765 | chr2_130159538_- | 7.44879828173025e-05 | 0.31769056267753 | 2.08065053456934e-08 | 0.437988751609011 | 0.0380229276084748 | 0.169580730827479 |
| DLPFC | ADediting_810766 | chr2_130159555_- | 4.63216022904943e-07 | 0.281628796916548 | 4.1704495504739e-09 | 0.325963268082199 | 0.00733998803508159 | 0.151999537870033 |
| DLPFC | ADediting_810769 | chr2_130159569_- | 4.82345792844175e-09 | 0.324698008903655 | 6.27348479497165e-13 | 0.393593736930301 | 0.000503030642743149 | 0.196466152379732 |
| CER | ADediting_810769 | chr2_130159569_- | 6.10460011169842e-09 | 0.452532416301451 | 2.99320599163356e-08 | 0.433541003630631 | 0.006354506413579 | 0.221885828426516 |
| DLPFC | ADediting_810771 | chr2_130159594_- | 4.67540654332197e-07 | 0.281533486907698 | 8.82061936621403e-12 | 0.374894765999548 | 0.000114485402383419 | 0.217352511288319 |
| CER | ADediting_810771 | chr2_130159594_- | 3.88179080891404e-07 | 0.400239683343086 | 8.56447668864627e-09 | 0.448584301932233 | 0.0116074459859798 | 0.205585906228151 |
| TCX | ADediting_810771 | chr2_130159594_- | 7.72790544212097e-05 | 0.317022354783904 | 0.107430494160274 | 0.131972170172681 | 0.000698144950402986 | 0.273798669497331 |
| DLPFC | ADediting_810773 | chr2_130159612_- | 1.9985924915495e-08 | 0.312015137794523 | 3.80055034421861e-10 | 0.346010165451726 | 0.000219300480059006 | 0.208432504578182 |
| CER | ADediting_810773 | chr2_130159612_- | 9.56162297106877e-05 | 0.313123329577699 | 0.00109602550643526 | 0.264019564774029 | 0.746305029194044 | 0.0266330236694672 |
| CER | ADediting_810774 | chr2_130159624_- | 0.000242330589985513 | 0.295427416672907 | 1.99642954246563e-06 | 0.376887287827508 | 0.00199943980478419 | 0.250385957172575 |
| CER | ADediting_810775 | chr2_130159636_- | 9.48443434250214e-07 | 0.387723971733423 | 0.000182927590318958 | 0.300898276160764 | 0.0103407113709657 | 0.208801621018482 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 1.3076962977135e-34 | 0.622193426960673 | 5.83479488775137e-58 | 0.75313364137494 | 2.27796222032005e-09 | 0.331161914400137 |
| AC | 2.46959033474396e-59 | 0.809684417653991 | 1.67429204379471e-42 | 0.727753488961153 | 1.60459253494803e-26 | 0.60664897351601 |
| PCC | 9.91224194444864e-35 | 0.742527209919653 | 2.54653995671714e-35 | 0.746810745221314 | 2.69861712187485e-07 | 0.361847441836074 |
| CER | 1.02689907017511e-13 | 0.559189523837713 | 3.14012275443042e-33 | 0.789816508244827 | 9.67697806020785e-08 | 0.418737460496211 |
| TCX | 2.12178244029991e-11 | 0.512048465490208 | 0.00227532645399303 | 0.247357365909061 | 4.82072382653455e-19 | 0.645454693441993 |
| FP | 9.17267060923216e-24 | 0.661474076156836 | 5.1978758545581e-15 | 0.542515210840262 | 1.13648037806956e-16 | 0.569180645944088 |
| IFG | 6.57950034643528e-06 | 0.770616930992882 | 2.52201683773346e-05 | 0.738241859307049 | 0.000718744833611846 | 0.631040252339768 |
| PG | 0.0054976890955448 | 0.202817322248436 | 0.0129350660303682 | 0.181952183214705 | 5.19423626307216e-08 | 0.386216804134995 |
| STG | 1.22198558611897e-10 | 0.631205464341209 | 0.000180925905406607 | 0.397518209932755 | 2.39040754262741e-05 | 0.443473096920074 |
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Relation with AD stages for SMPD4 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_810678 | chr2_130158000_- | 9.77990850182419e-06 | 0.411302441277258 |
| CER | ADediting_810679 | chr2_130158008_- | 0.000379488475813529 | 0.335895732209575 |
| CER | ADediting_810688 | chr2_130158088_- | 0.000268491919748329 | 0.343883370438384 |
| CER | ADediting_810702 | chr2_130158473_- | 0.000336301496910595 | 0.338709192328661 |
| CER | ADediting_810726 | chr2_130159123_- | 0.000496648525119681 | 0.329532670111725 |
| CER | ADediting_810738 | chr2_130159208_- | 0.000164532467349917 | 0.354836754591877 |
| CER | ADediting_810743 | chr2_130159227_- | 0.00023210258697085 | 0.347182800471489 |
| CER | ADediting_810744 | chr2_130159241_- | 0.00140434548083457 | 0.303565677224504 |
| CER | ADediting_810745 | chr2_130159262_- | 0.000478141268979952 | 0.330439117073818 |
| CER | ADediting_810753 | chr2_130159447_- | 0.000794571559900994 | 0.318078969001563 |
| CER | ADediting_810758 | chr2_130159490_- | 0.000332690503897099 | 0.338959298144581 |
| CER | ADediting_810763 | chr2_130159526_- | 0.000894093990647457 | 0.315130862987018 |
| CER | ADediting_810765 | chr2_130159538_- | 0.000179742479013451 | 0.352888361871662 |
| TCX | ADediting_810674 | chr2_130157896_- | 0.00175562365209896 | 0.30040004614661 |
| TCX | ADediting_810679 | chr2_130158008_- | 0.000461481975924016 | 0.334284100617361 |
| TCX | ADediting_810721 | chr2_130159080_- | 0.00158694035396246 | 0.303104592495229 |
| TCX | ADediting_810723 | chr2_130159092_- | 0.000776440327008151 | 0.32155251680436 |
| TCX | ADediting_810734 | chr2_130159173_- | 0.00170719581350808 | 0.301151509619022 |
| TCX | ADediting_810735 | chr2_130159176_- | 0.000301346001172167 | 0.344321280745821 |
| TCX | ADediting_810742 | chr2_130159222_- | 0.000178388102598659 | 0.356225916042743 |
| TCX | ADediting_810752 | chr2_130159422_- | 0.00024115927365884 | 0.349437708708322 |
| TCX | ADediting_810753 | chr2_130159447_- | 0.000209478990930448 | 0.352627581094707 |
| TCX | ADediting_810754 | chr2_130159454_- | 0.000311761519222533 | 0.343533261919602 |
| TCX | ADediting_810755 | chr2_130159459_- | 0.000316434855768899 | 0.343187552586945 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 3.57031213820153e-08 | 0.500111020745195 |
| TCX | 2.38642606286212e-07 | 0.476757306226117 |
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RelatedDrugs for SMPD4 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for SMPD4 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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