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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for MRPL20

check button Gene summary
Gene informationGene symbol

MRPL20

Gene ID

55052

Gene namemitochondrial ribosomal protein L20
SynonymsL20mt|MRP-L20
Cytomap

1p36.33

Type of geneprotein-coding
Description39S ribosomal protein L20, mitochondrialmitochondrial large ribosomal subunit protein bL20m
Modification date20200313
UniProtAcc

Q9BYC9,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for MRPL20

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_13053(1402726, -), ADediting_13054(1402738, -), ADediting_13055(1402739, -), ADediting_13056(1402786, -), ADediting_13057(1402811, -), ADediting_13058(1402813, -), ADediting_13059(1402820, -), ADediting_13060(1402872, -), ADediting_13061(1402877, -), ADediting_13062(1402884, -), ADediting_13063(1402885, -), ADediting_13064(1402907, -), ADediting_13065(1402935, -), ADediting_13066(1402939, -), ADediting_13067(1402947, -), ADediting_13068(1402955, -), ADediting_13069(1402961, -), ADediting_13070(1402970, -), ADediting_13071(1402985, -), ADediting_13072(1403005, -), ADediting_13073(1403007, -), ADediting_13074(1403012, -), ADediting_13075(1403017, -), ADediting_13076(1403029, -), ADediting_13077(1403045, -), ADediting_13078(1403059, -), ADediting_13079(1403060, -), ADediting_13080(1403066, -), ADediting_13081(1403067, -), ADediting_13082(1403068, -), ADediting_13083(1403082, -), ADediting_13084(1403091, -), ADediting_13085(1403096, -), ADediting_13086(1403115, -), ADediting_13087(1403304, -), ADediting_13088(1403316, -), ADediting_13089(1403319, -), ADediting_13090(1403333, -), ADediting_13091(1403340, -), ADediting_13092(1403344, -), ADediting_13093(1403355, -), ADediting_13094(1403365, -), ADediting_13095(1403372, -), ADediting_13096(1403376, -), ADediting_13097(1403382, -), ADediting_13098(1403404, -), ADediting_13099(1403445, -), ADediting_13100(1403447, -), ADediting_13101(1403471, -), ADediting_13102(1403476, -), ADediting_13103(1403479, -), ADediting_13104(1403509, -), ADediting_13105(1403514, -), ADediting_13106(1403515, -), ADediting_13107(1403533, -), ADediting_13113(1403902, -), ADediting_13114(1403904, -), ADediting_13115(1403970, -), ADediting_13116(1404000, -), ADediting_13117(1404012, -), ADediting_13118(1404034, -), ADediting_13119(1404035, -), ADediting_13123(1404066, -), ADediting_13124(1404124, -), ADediting_13125(1404265, -), ADediting_13126(1404269, -), ADediting_13127(1404282, -), ADediting_13128(1404292, -), ADediting_13129(1404314, -), ADediting_13130(1404359, -), ADediting_13131(1404383, -), ADediting_13132(1404388, -), ADediting_13133(1404421, -), ADediting_13134(1404426, -), ADediting_13135(1404427, -), ADediting_13136(1404563, -), ADediting_13137(1404622, -), ADediting_13138(1404639, -), ADediting_13139(1404675, -), ADediting_13140(1404678, -), ADediting_13141(1404680, -), ADediting_13142(1404684, -), ADediting_13143(1404695, -), ADediting_13144(1404702, -), ADediting_13145(1404704, -), ADediting_13146(1404728, -), ADediting_13147(1404733, -), ADediting_13148(1404741, -), ADediting_13149(1404755, -), ADediting_13152(1404765, -), ADediting_13172(1405101, -), ADediting_13173(1405183, -), ADediting_13174(1405184, -), ADediting_13175(1405193, -), ADediting_13176(1405266, -), ADediting_13177(1405316, -), ADediting_13178(1405321, -), ADediting_13179(1405334, -), ADediting_13189(1406239, -), ADediting_1514276(1402719, -), ADediting_1514277(1402997, -), ADediting_1514278(1403042, -), ADediting_1514279(1403072, -), ADediting_1514280(1403349, -), ADediting_1514281(1403359, -), ADediting_1514282(1403411, -), ADediting_1514283(1403417, -), ADediting_1514284(1403432, -), ADediting_1514285(1403437, -), ADediting_1514286(1403438, -), ADediting_1514287(1403448, -), ADediting_1514288(1403953, -), ADediting_1514289(1404201, -), ADediting_1514290(1404259, -), ADediting_1514291(1404326, -), ADediting_1514292(1404668, -), ADediting_1514293(1404677, -), ADediting_1514294(1405130, -), ADediting_1514295(1405242, -), ADediting_1514296(1405256, -), ADediting_1514297(1406111, -), ADediting_1514298(1406190, -), ADediting_1514299(1406193, -), ADediting_1514300(1406238, -), ADediting_1514301(1406287, -), ADediting_1514302(1406311, -), ADediting_1514303(1406328, -), ADediting_1596299(1405020, -),

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RNA editing positional annotations for MRPL20 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_13053chr1_1402726_-intronic
ADediting_13054chr1_1402738_-intronic
ADediting_13055chr1_1402739_-intronic
ADediting_13056chr1_1402786_-intronic
ADediting_13057chr1_1402811_-intronic
ADediting_13058chr1_1402813_-intronic
ADediting_13059chr1_1402820_-intronic
ADediting_13060chr1_1402872_-intronic
ADediting_13061chr1_1402877_-intronic
ADediting_13062chr1_1402884_-intronic
ADediting_13063chr1_1402885_-intronic
ADediting_13064chr1_1402907_-intronic
ADediting_13065chr1_1402935_-intronic
ADediting_13066chr1_1402939_-intronic
ADediting_13067chr1_1402947_-intronic
ADediting_13068chr1_1402955_-intronic
ADediting_13069chr1_1402961_-intronic
ADediting_13070chr1_1402970_-intronic
ADediting_13071chr1_1402985_-intronic
ADediting_13072chr1_1403005_-intronic
ADediting_13073chr1_1403007_-intronic
ADediting_13074chr1_1403012_-intronic
ADediting_13075chr1_1403017_-intronic
ADediting_13076chr1_1403029_-intronic
ADediting_13077chr1_1403045_-intronic
ADediting_13078chr1_1403059_-intronic
ADediting_13079chr1_1403060_-intronic
ADediting_13080chr1_1403066_-intronic
ADediting_13081chr1_1403067_-intronic
ADediting_13082chr1_1403068_-intronic
ADediting_13083chr1_1403082_-intronic
ADediting_13084chr1_1403091_-intronic
ADediting_13085chr1_1403096_-intronic
ADediting_13086chr1_1403115_-intronic
ADediting_13087chr1_1403304_-intronic
ADediting_13088chr1_1403316_-intronic
ADediting_13089chr1_1403319_-intronic
ADediting_13090chr1_1403333_-intronic
ADediting_13091chr1_1403340_-intronic
ADediting_13092chr1_1403344_-intronic
ADediting_13093chr1_1403355_-intronic
ADediting_13094chr1_1403365_-intronic
ADediting_13095chr1_1403372_-intronic
ADediting_13096chr1_1403376_-intronic
ADediting_13097chr1_1403382_-intronic
ADediting_13098chr1_1403404_-intronic
ADediting_13099chr1_1403445_-intronic
ADediting_13100chr1_1403447_-intronic
ADediting_13101chr1_1403471_-intronic
ADediting_13102chr1_1403476_-intronic
ADediting_13103chr1_1403479_-intronic
ADediting_13104chr1_1403509_-intronic
ADediting_13105chr1_1403514_-intronic
ADediting_13106chr1_1403515_-intronic
ADediting_13107chr1_1403533_-intronic
ADediting_13113chr1_1403902_-intronic
ADediting_13114chr1_1403904_-intronic
ADediting_13115chr1_1403970_-intronic
ADediting_13116chr1_1404000_-intronic
ADediting_13117chr1_1404012_-intronic
ADediting_13118chr1_1404034_-intronic
ADediting_13119chr1_1404035_-intronic
ADediting_13123chr1_1404066_-intronic
ADediting_13124chr1_1404124_-intronic
ADediting_13125chr1_1404265_-intronic
ADediting_13126chr1_1404269_-intronic
ADediting_13127chr1_1404282_-intronic
ADediting_13128chr1_1404292_-intronic
ADediting_13129chr1_1404314_-intronic
ADediting_13130chr1_1404359_-intronic
ADediting_13131chr1_1404383_-intronic
ADediting_13132chr1_1404388_-intronic
ADediting_13133chr1_1404421_-intronic
ADediting_13134chr1_1404426_-intronic
ADediting_13135chr1_1404427_-intronic
ADediting_13136chr1_1404563_-intronic
ADediting_13137chr1_1404622_-intronic
ADediting_13138chr1_1404639_-intronic
ADediting_13139chr1_1404675_-intronic
ADediting_13140chr1_1404678_-intronic
ADediting_13141chr1_1404680_-intronic
ADediting_13142chr1_1404684_-intronic
ADediting_13143chr1_1404695_-intronic
ADediting_13144chr1_1404702_-intronic
ADediting_13145chr1_1404704_-intronic
ADediting_13146chr1_1404728_-intronic
ADediting_13147chr1_1404733_-intronic
ADediting_13148chr1_1404741_-intronic
ADediting_13149chr1_1404755_-intronic
ADediting_13152chr1_1404765_-intronic
ADediting_13172chr1_1405101_-intronic
ADediting_13173chr1_1405183_-UTR3
ADediting_13174chr1_1405184_-UTR3
ADediting_13175chr1_1405193_-UTR3
ADediting_13176chr1_1405266_-UTR3
ADediting_13177chr1_1405316_-UTR3
ADediting_13178chr1_1405321_-UTR3
ADediting_13179chr1_1405334_-UTR3
ADediting_13189chr1_1406239_-intronic
ADediting_1514276chr1_1402719_-intronic
ADediting_1514277chr1_1402997_-intronic
ADediting_1514278chr1_1403042_-intronic
ADediting_1514279chr1_1403072_-intronic
ADediting_1514280chr1_1403349_-intronic
ADediting_1514281chr1_1403359_-intronic
ADediting_1514282chr1_1403411_-intronic
ADediting_1514283chr1_1403417_-intronic
ADediting_1514284chr1_1403432_-intronic
ADediting_1514285chr1_1403437_-intronic
ADediting_1514286chr1_1403438_-intronic
ADediting_1514287chr1_1403448_-intronic
ADediting_1514288chr1_1403953_-intronic
ADediting_1514289chr1_1404201_-intronic
ADediting_1514290chr1_1404259_-intronic
ADediting_1514291chr1_1404326_-intronic
ADediting_1514292chr1_1404668_-intronic
ADediting_1514293chr1_1404677_-intronic
ADediting_1514294chr1_1405130_-UTR3
ADediting_1514295chr1_1405242_-UTR3
ADediting_1514296chr1_1405256_-UTR3
ADediting_1514297chr1_1406111_-intronic
ADediting_1514298chr1_1406190_-intronic
ADediting_1514299chr1_1406193_-intronic
ADediting_1514300chr1_1406238_-intronic
ADediting_1514301chr1_1406287_-intronic
ADediting_1514302chr1_1406311_-intronic
ADediting_1514303chr1_1406328_-intronic
ADediting_1596299chr1_1405020_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_13053chr1_1402726_-SINEAluName=AluSp
ADediting_13054chr1_1402738_-SINEAluName=AluSp
ADediting_13055chr1_1402739_-SINEAluName=AluSp
ADediting_13056chr1_1402786_-SINEAluName=AluSp
ADediting_13057chr1_1402811_-SINEAluName=AluSp
ADediting_13058chr1_1402813_-SINEAluName=AluSp
ADediting_13059chr1_1402820_-SINEAluName=AluSp
ADediting_13060chr1_1402872_-SINEAluName=AluY
ADediting_13061chr1_1402877_-SINEAluName=AluY
ADediting_13062chr1_1402884_-SINEAluName=AluY
ADediting_13063chr1_1402885_-SINEAluName=AluY
ADediting_13064chr1_1402907_-SINEAluName=AluY
ADediting_13065chr1_1402935_-SINEAluName=AluY
ADediting_13066chr1_1402939_-SINEAluName=AluY
ADediting_13067chr1_1402947_-SINEAluName=AluY
ADediting_13068chr1_1402955_-SINEAluName=AluY
ADediting_13069chr1_1402961_-SINEAluName=AluY
ADediting_13070chr1_1402970_-SINEAluName=AluY
ADediting_13071chr1_1402985_-SINEAluName=AluY
ADediting_13072chr1_1403005_-SINEAluName=AluY
ADediting_13073chr1_1403007_-SINEAluName=AluY
ADediting_13074chr1_1403012_-SINEAluName=AluY
ADediting_13075chr1_1403017_-SINEAluName=AluY
ADediting_13076chr1_1403029_-SINEAluName=AluY
ADediting_13077chr1_1403045_-SINEAluName=AluY
ADediting_13078chr1_1403059_-SINEAluName=AluY
ADediting_13079chr1_1403060_-SINEAluName=AluY
ADediting_13080chr1_1403066_-SINEAluName=AluY
ADediting_13081chr1_1403067_-SINEAluName=AluY
ADediting_13082chr1_1403068_-SINEAluName=AluY
ADediting_13083chr1_1403082_-SINEAluName=AluY
ADediting_13084chr1_1403091_-SINEAluName=AluY
ADediting_13085chr1_1403096_-SINEAluName=AluY
ADediting_13086chr1_1403115_-SINEAluName=AluY
ADediting_13087chr1_1403304_-SINEAluName=AluY
ADediting_13088chr1_1403316_-SINEAluName=AluY
ADediting_13089chr1_1403319_-SINEAluName=AluY
ADediting_13090chr1_1403333_-SINEAluName=AluY
ADediting_13091chr1_1403340_-SINEAluName=AluY
ADediting_13092chr1_1403344_-SINEAluName=AluY
ADediting_13093chr1_1403355_-SINEAluName=AluY
ADediting_13094chr1_1403365_-SINEAluName=AluY
ADediting_13095chr1_1403372_-SINEAluName=AluY
ADediting_13096chr1_1403376_-SINEAluName=AluY
ADediting_13097chr1_1403382_-SINEAluName=AluY
ADediting_13098chr1_1403404_-SINEAluName=AluY
ADediting_13099chr1_1403445_-SINEAluName=AluY
ADediting_13100chr1_1403447_-SINEAluName=AluY
ADediting_13101chr1_1403471_-SINEAluName=AluY
ADediting_13102chr1_1403476_-SINEAluName=AluY
ADediting_13103chr1_1403479_-SINEAluName=AluY
ADediting_13104chr1_1403509_-SINEAluName=AluY
ADediting_13105chr1_1403514_-SINEAluName=AluY
ADediting_13106chr1_1403515_-SINEAluName=AluY
ADediting_13107chr1_1403533_-SINEAluName=AluY
ADediting_13113chr1_1403902_-SINEAluName=AluSx
ADediting_13114chr1_1403904_-SINEAluName=AluSx
ADediting_13115chr1_1403970_-SINEAluName=AluSx
ADediting_13116chr1_1404000_-SINEAluName=AluSx
ADediting_13117chr1_1404012_-SINEAluName=AluSx
ADediting_13118chr1_1404034_-SINEAluName=AluSx
ADediting_13119chr1_1404035_-SINEAluName=AluSx
ADediting_13123chr1_1404066_-SINEAluName=AluSx
ADediting_13124chr1_1404124_-SINEAluName=AluSx
ADediting_13125chr1_1404265_-SINEAluName=AluY
ADediting_13126chr1_1404269_-SINEAluName=AluY
ADediting_13127chr1_1404282_-SINEAluName=AluY
ADediting_13128chr1_1404292_-SINEAluName=AluY
ADediting_13129chr1_1404314_-SINEAluName=AluY
ADediting_13130chr1_1404359_-SINEAluName=AluY
ADediting_13131chr1_1404383_-SINEAluName=AluY
ADediting_13132chr1_1404388_-SINEAluName=AluY
ADediting_13133chr1_1404421_-SINEAluName=AluY
ADediting_13134chr1_1404426_-SINEAluName=AluY
ADediting_13135chr1_1404427_-SINEAluName=AluY
ADediting_13136chr1_1404563_-SINEAluName=AluSc8
ADediting_13137chr1_1404622_-SINEAluName=AluSc8
ADediting_13138chr1_1404639_-SINEAluName=AluSc8
ADediting_13139chr1_1404675_-SINEAluName=AluSc8
ADediting_13140chr1_1404678_-SINEAluName=AluSc8
ADediting_13141chr1_1404680_-SINEAluName=AluSc8
ADediting_13142chr1_1404684_-SINEAluName=AluSc8
ADediting_13143chr1_1404695_-SINEAluName=AluSc8
ADediting_13144chr1_1404702_-SINEAluName=AluSc8
ADediting_13145chr1_1404704_-SINEAluName=AluSc8
ADediting_13146chr1_1404728_-SINEAluName=AluSc8
ADediting_13147chr1_1404733_-SINEAluName=AluSc8
ADediting_13148chr1_1404741_-SINEAluName=AluSc8
ADediting_13149chr1_1404755_-SINEAluName=AluSc8
ADediting_13152chr1_1404765_-SINEAluName=AluSc8
ADediting_13172chr1_1405101_-SINEAluName=AluSx1
ADediting_13173chr1_1405183_-SINEAluName=AluSx1
ADediting_13174chr1_1405184_-SINEAluName=AluSx1
ADediting_13175chr1_1405193_-SINEAluName=AluSx1
ADediting_13176chr1_1405266_-SINEAluName=AluSx1
ADediting_13177chr1_1405316_-SINEAluName=AluJo
ADediting_13178chr1_1405321_-SINEAluName=AluJo
ADediting_13179chr1_1405334_-SINEAluName=AluJo
ADediting_13189chr1_1406239_-SINEAluName=AluSz
ADediting_1514276chr1_1402719_-SINEAluName=AluSp
ADediting_1514277chr1_1402997_-SINEAluName=AluY
ADediting_1514278chr1_1403042_-SINEAluName=AluY
ADediting_1514279chr1_1403072_-SINEAluName=AluY
ADediting_1514280chr1_1403349_-SINEAluName=AluY
ADediting_1514281chr1_1403359_-SINEAluName=AluY
ADediting_1514282chr1_1403411_-SINEAluName=AluY
ADediting_1514283chr1_1403417_-SINEAluName=AluY
ADediting_1514284chr1_1403432_-SINEAluName=AluY
ADediting_1514285chr1_1403437_-SINEAluName=AluY
ADediting_1514286chr1_1403438_-SINEAluName=AluY
ADediting_1514287chr1_1403448_-SINEAluName=AluY
ADediting_1514288chr1_1403953_-SINEAluName=AluSx
ADediting_1514289chr1_1404201_-SINEAluName=AluY
ADediting_1514290chr1_1404259_-SINEAluName=AluY
ADediting_1514291chr1_1404326_-SINEAluName=AluY
ADediting_1514292chr1_1404668_-SINEAluName=AluSc8
ADediting_1514293chr1_1404677_-SINEAluName=AluSc8
ADediting_1514294chr1_1405130_-SINEAluName=AluSx1
ADediting_1514295chr1_1405242_-SINEAluName=AluSx1
ADediting_1514296chr1_1405256_-SINEAluName=AluSx1
ADediting_1514297chr1_1406111_-SINEAluName=AluSz
ADediting_1514298chr1_1406190_-SINEAluName=AluSz
ADediting_1514299chr1_1406193_-SINEAluName=AluSz
ADediting_1514300chr1_1406238_-SINEAluName=AluSz
ADediting_1514301chr1_1406287_-SINEAluName=AluSz
ADediting_1514302chr1_1406311_-SINEAluName=AluSz
ADediting_1514303chr1_1406328_-SINEAluName=AluSz
ADediting_1596299chr1_1405020_-SINEAluName=AluSx1

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RNA A-to-I editing events in the alternative splicing sites for MRPL20

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for MRPL20

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for MRPL20

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for MRPL20

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_13173chr1_1405183_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-3158-3pchr1140517914051857mer-m814051781405203154-23.05
ADediting_13173chr1_1405183_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-412-3pchr1140518314051897mer-m814051821405204153-17.3
ADediting_13173chr1_1405183_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-6754-3pchr1140518314051897mer-m814051821405202150-16.33
ADediting_13174chr1_1405184_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-1182chr1140517914051857mer-m814051781405200143-14.72
ADediting_13174chr1_1405184_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-1229-3pchr1140518314051897mer-m814051821405206154-17.99
ADediting_13174chr1_1405184_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-6511a-3pchr1140518314051908mer-1a14051831405201142-14.89
ADediting_13174chr1_1405184_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-6511b-3pchr1140518314051908mer-1a14051831405205145-17.85
ADediting_13175chr1_1405193_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-3190-5pchr1140519314051997mer-m814051921405211159-26.31
ADediting_13176chr1_1405266_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-7108-3pchr1140526414052707mer-m814052631405282144-20.51
ADediting_13177chr1_1405316_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-500b-3pchr1140531114053188mer-1a14053111405330162-22.75
ADediting_13178chr1_1405321_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-5704chr1140531614053227mer-m814053151405344141-18.53
ADediting_13178chr1_1405321_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-759chr1140532114053277mer-m814053201405341150-15.28
ADediting_13179chr1_1405334_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-593-5pchr1140533114053388mer-1a14053311405355156-23.6
ADediting_13179chr1_1405334_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-767-5pchr1140533314053397mer-m814053321405355152-18.37
ADediting_13179chr1_1405334_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-891a-3pchr1140533014053367mer-m814053291405351148-18.64
ADediting_13179chr1_1405334_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-9851-3pchr1140533114053388mer-1a14053311405351154-20.55
ADediting_1514294chr1_1405130_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-764chr1140513014051367mer-m814051291405150149-23.87
ADediting_1514295chr1_1405242_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-371a-3pchr1140523714052437mer-m814052361405258149-17.94
ADediting_1514296chr1_1405256_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-615-3pchr1140525514052617mer-m814052541405273144-23.99

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_13173chr1_1405183_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-6823-5pchr1140517814051847mer-m814051771405197143-16.64
ADediting_13175chr1_1405193_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-1306-3pchr1140519114051977mer-m814051901405207148-21
ADediting_13176chr1_1405266_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-3620-3pchr1140526114052677mer-m814052601405279149-23.95
ADediting_13176chr1_1405266_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-6752-3pchr1140526314052697mer-m814052621405284152-23.04
ADediting_13177chr1_1405316_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-645chr1140531514053217mer-m814053141405331154-21.34
ADediting_1514295chr1_1405242_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-450b-3pchr1140524214052487mer-m814052411405264149-21.74
ADediting_1514295chr1_1405242_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-6506-5pchr1140524114052477mer-m814052401405265147-17.33
ADediting_1514295chr1_1405242_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-769-3pchr1140524214052487mer-m814052411405261154-26.03
ADediting_1514296chr1_1405256_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-1199-5pchr1140525514052617mer-m814052541405275145-27.86
ADediting_1514296chr1_1405256_-ENSG00000242485.6ENST00000482352.1MRPL20-203hsa-miR-6807-5pchr1140525614052627mer-m814052551405276140-14.26

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_13189chr1_1406239_-ENSG00000242485.6ENST00000493287.5MRPL20-206hsa-miR-668-3pchr1140623714062437mer-m814062361406258150-19.86
ADediting_1514300chr1_1406238_-ENSG00000242485.6ENST00000493287.5MRPL20-206hsa-miR-5690chr1140623514062417mer-m814062341406254145-15.58
ADediting_1514301chr1_1406287_-ENSG00000242485.6ENST00000477686.1MRPL20-202hsa-miR-20a-3pchr1140628714062937mer-m814062861406304148-13.41
ADediting_1514301chr1_1406287_-ENSG00000242485.6ENST00000477686.1MRPL20-202hsa-miR-485-5pchr1140628314062897mer-m814062821406301142-14.37
ADediting_1514301chr1_1406287_-ENSG00000242485.6ENST00000477686.1MRPL20-202hsa-miR-6884-5pchr1140628314062897mer-m814062821406305143-17.08
ADediting_1514301chr1_1406287_-ENSG00000242485.6ENST00000493287.5MRPL20-206hsa-miR-20a-3pchr1140628714062937mer-m814062861406304148-13.41
ADediting_1514301chr1_1406287_-ENSG00000242485.6ENST00000493287.5MRPL20-206hsa-miR-485-5pchr1140628314062897mer-m814062821406301142-14.37
ADediting_1514301chr1_1406287_-ENSG00000242485.6ENST00000493287.5MRPL20-206hsa-miR-6884-5pchr1140628314062897mer-m814062821406305143-17.08
ADediting_1514302chr1_1406311_-ENSG00000242485.6ENST00000477686.1MRPL20-202hsa-miR-324-3pchr1140630814063147mer-m814063071406329148-24.16
ADediting_1514302chr1_1406311_-ENSG00000242485.6ENST00000477686.1MRPL20-202hsa-miR-4252chr1140630714063137mer-m814063061406326149-21.82
ADediting_1514302chr1_1406311_-ENSG00000242485.6ENST00000477686.1MRPL20-202hsa-miR-4793-3pchr1140631114063177mer-m814063101406332157-22.82
ADediting_1514303chr1_1406328_-ENSG00000242485.6ENST00000477686.1MRPL20-202hsa-miR-4486chr1140632314063297mer-m814063221406339147-21.03

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_13189chr1_1406239_-ENSG00000242485.6ENST00000493287.5MRPL20-206hsa-miR-935chr1140623514062417mer-m814062341406257141-11.47
ADediting_1514300chr1_1406238_-ENSG00000242485.6ENST00000493287.5MRPL20-206hsa-miR-935chr1140623514062417mer-m814062341406257141-11.47
ADediting_1514301chr1_1406287_-ENSG00000242485.6ENST00000477686.1MRPL20-202hsa-miR-377-5pchr1140628314062897mer-m814062821406303148-15.87
ADediting_1514301chr1_1406287_-ENSG00000242485.6ENST00000477686.1MRPL20-202hsa-miR-6086chr1140628314062897mer-m814062821406301144-16.83
ADediting_1514301chr1_1406287_-ENSG00000242485.6ENST00000493287.5MRPL20-206hsa-miR-377-5pchr1140628314062897mer-m814062821406303148-15.87
ADediting_1514301chr1_1406287_-ENSG00000242485.6ENST00000493287.5MRPL20-206hsa-miR-6086chr1140628314062897mer-m814062821406301144-16.83
ADediting_1514302chr1_1406311_-ENSG00000242485.6ENST00000477686.1MRPL20-202hsa-miR-32-5pchr1140631014063167mer-m814063091406331147-12.53
ADediting_1514302chr1_1406311_-ENSG00000242485.6ENST00000477686.1MRPL20-202hsa-miR-363-3pchr1140631014063167mer-m814063091406330147-16.12
ADediting_1514302chr1_1406311_-ENSG00000242485.6ENST00000477686.1MRPL20-202hsa-miR-92a-3pchr1140631014063167mer-m814063091406326155-26.92
ADediting_1514303chr1_1406328_-ENSG00000242485.6ENST00000477686.1MRPL20-202hsa-miR-1262chr1140632414063307mer-m814063231406345144-16.39
ADediting_1514303chr1_1406328_-ENSG00000242485.6ENST00000477686.1MRPL20-202hsa-miR-4701-3pchr1140632414063307mer-m814063231406343153-20.53
ADediting_1514303chr1_1406328_-ENSG00000242485.6ENST00000477686.1MRPL20-202hsa-miR-542-3pchr1140632714063337mer-m814063261406346148-15.88
ADediting_1514303chr1_1406328_-ENSG00000242485.6ENST00000477686.1MRPL20-202hsa-miR-6736-5pchr1140632414063307mer-m814063231406343148-22.44

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337758chr7_5495892_-ENSG00000242485.6ENST00000492508.1MRPL20-205hsa-miR-589-5pchr1140250914025157mer-m814025081402532154-19.51

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1097295chr3_85385762_+ENSG00000242485.6ENST00000344843.12MRPL20-201hsa-miR-5688chr1140203114020377mer-m814020301402048149-9.76

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for MRPL20

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000493287.5lncRNASoverviewSoverview
ENST00000482352.1protein_codingSoverviewSoverview
ENST00000477686.1lncRNASoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_1514294ENST00000482352.1chr1_1405130_-1028-394.20-392.00-403.00
ADediting_13173ENST00000482352.1chr1_1405183_-975-392.40-392.00-403.00
ADediting_13174ENST00000482352.1chr1_1405184_-974-397.80-392.00-403.00
ADediting_13175ENST00000482352.1chr1_1405193_-965-395.60-392.00-403.00
ADediting_1514295ENST00000482352.1chr1_1405242_-916-391.30-392.00-403.00
ADediting_1514296ENST00000482352.1chr1_1405256_-902-392.30-392.00-403.00
ADediting_13176ENST00000482352.1chr1_1405266_-892-391.30-392.00-403.00
ADediting_13177ENST00000482352.1chr1_1405316_-842-392.20-392.00-403.00
ADediting_13178ENST00000482352.1chr1_1405321_-837-390.70-392.00-403.00
ADediting_13179ENST00000482352.1chr1_1405334_-824-392.00-392.00-403.00

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_1514300ENST00000493287.5chr1_1406238_-70-158.10-156.30-158.80
ADediting_13189ENST00000493287.5chr1_1406239_-69-157.90-156.30-158.80
ADediting_1514301ENST00000493287.5chr1_1406287_-21-156.90-156.30-158.80
ADediting_1514301ENST00000477686.1chr1_1406287_-276-114.10-109.70-112.60
ADediting_1514302ENST00000477686.1chr1_1406311_-252-108.60-109.70-112.60
ADediting_1514303ENST00000477686.1chr1_1406328_-235-109.30-109.70-112.60

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Relation with ADAR for MRPL20

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_13067chr1_1402947_-0.3725825817588520.05081465741882610.990113625683468-0.000706618819923934.74976465330505e-090.324832197629947
DLPFCADediting_13071chr1_1402985_-0.9195322983668650.005760939163583540.365945120356256-0.05152316305797611.94961138462317e-080.312241679259034
TCXADediting_13138chr1_1404639_-0.1917708456515810.107171359426970.557014002189642-0.0483276658710334.75668785846895e-050.325713894329446

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC6.15012612358016e-410.6649909436699883.53491258650863e-560.7453530947998464.1415441269581e-070.282774256323929
AC1.68562578239091e-670.8390247551725888.58063253879648e-460.7466016938288331.42267510497333e-170.504844424899732
PCC4.32220273875613e-210.612955757980146.48518696505528e-220.6229117715114340.04174386461277670.147485957362957
TCX3.35200128811376e-140.5682185877294471.9472701518838e-090.465497536588740.6171427399458440.0411438800821151
FP4.21235424210477e-160.5603083031199735.33361542450466e-060.3336522430562760.5451722716917110.0456453646812778
IFG0.006261188250506330.5314332235814970.06548577666029880.3740329094503140.348714363541812-0.195612518649364
PG6.8616787396464e-320.7272161719452651.63323565762551e-150.5407063373532860.5920029119584620.0395479464576368
STG2.63359943956968e-130.6935112169706533.8604391266163e-070.5205558365621990.341466410101593-0.105079047543223

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Relation with AD stages for MRPL20

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
TCXADediting_13138chr1_1404639_-0.001596821697430090.302939134038667

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.

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RelatedDrugs for MRPL20

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for MRPL20

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource