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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for LURAP1 |
 Gene summary |
| Gene information | Gene symbol | LURAP1 | Gene ID | 541468 |
| Gene name | leucine rich adaptor protein 1 | |
| Synonyms | C1orf190|LRAP35a|LRP35A | |
| Cytomap | 1p34.1 | |
| Type of gene | protein-coding | |
| Description | leucine rich adaptor protein 1NF-kappa-B activator C1orf190leucine repeat adapter protein 35Aleucine repeat adaptor protein 35a | |
| Modification date | 20200313 | |
| UniProtAcc | Q96LR2, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| LURAP1 | GO:0001819 | positive regulation of cytokine production | 21048106 |
| LURAP1 | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling | 21048106 |
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RNA A-to-I events for LURAP1 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_120240(46220453, +), ADediting_120241(46220469, +), ADediting_120242(46220474, +), ADediting_120243(46220478, +), ADediting_120244(46220491, +), ADediting_120245(46220494, +), ADediting_120246(46220499, +), ADediting_120247(46220504, +), ADediting_120248(46220509, +), ADediting_120249(46220516, +), ADediting_120250(46220529, +), ADediting_120251(46220530, +), ADediting_120252(46220563, +), ADediting_120253(46220569, +), ADediting_120254(46220630, +), ADediting_120255(46220650, +), ADediting_120256(46220661, +), ADediting_120257(46220675, +), ADediting_120258(46220676, +), |
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RNA editing positional annotations for LURAP1 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_120240 | chr1_46220453_+ | UTR3 |
| ADediting_120241 | chr1_46220469_+ | UTR3 |
| ADediting_120242 | chr1_46220474_+ | UTR3 |
| ADediting_120243 | chr1_46220478_+ | UTR3 |
| ADediting_120244 | chr1_46220491_+ | UTR3 |
| ADediting_120245 | chr1_46220494_+ | UTR3 |
| ADediting_120246 | chr1_46220499_+ | UTR3 |
| ADediting_120247 | chr1_46220504_+ | UTR3 |
| ADediting_120248 | chr1_46220509_+ | UTR3 |
| ADediting_120249 | chr1_46220516_+ | UTR3 |
| ADediting_120250 | chr1_46220529_+ | UTR3 |
| ADediting_120251 | chr1_46220530_+ | UTR3 |
| ADediting_120252 | chr1_46220563_+ | UTR3 |
| ADediting_120253 | chr1_46220569_+ | UTR3 |
| ADediting_120254 | chr1_46220630_+ | UTR3 |
| ADediting_120255 | chr1_46220650_+ | UTR3 |
| ADediting_120256 | chr1_46220661_+ | UTR3 |
| ADediting_120257 | chr1_46220675_+ | UTR3 |
| ADediting_120258 | chr1_46220676_+ | UTR3 |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_120240 | chr1_46220453_+ | SINE | Alu | Name=AluJb |
| ADediting_120241 | chr1_46220469_+ | SINE | Alu | Name=AluJb |
| ADediting_120242 | chr1_46220474_+ | SINE | Alu | Name=AluJb |
| ADediting_120243 | chr1_46220478_+ | SINE | Alu | Name=AluJb |
| ADediting_120244 | chr1_46220491_+ | SINE | Alu | Name=AluJb |
| ADediting_120245 | chr1_46220494_+ | SINE | Alu | Name=AluJb |
| ADediting_120246 | chr1_46220499_+ | SINE | Alu | Name=AluJb |
| ADediting_120247 | chr1_46220504_+ | SINE | Alu | Name=AluJb |
| ADediting_120248 | chr1_46220509_+ | SINE | Alu | Name=AluJb |
| ADediting_120249 | chr1_46220516_+ | SINE | Alu | Name=AluJb |
| ADediting_120250 | chr1_46220529_+ | SINE | Alu | Name=AluJb |
| ADediting_120251 | chr1_46220530_+ | SINE | Alu | Name=AluJb |
| ADediting_120252 | chr1_46220563_+ | SINE | Alu | Name=AluJb |
| ADediting_120253 | chr1_46220569_+ | SINE | Alu | Name=AluJb |
| ADediting_120254 | chr1_46220630_+ | SINE | Alu | Name=AluJb |
| ADediting_120255 | chr1_46220650_+ | SINE | Alu | Name=AluJb |
| ADediting_120256 | chr1_46220661_+ | SINE | Alu | Name=AluJb |
| ADediting_120257 | chr1_46220675_+ | SINE | Alu | Name=AluJb |
| ADediting_120258 | chr1_46220676_+ | SINE | Alu | Name=AluJb |
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RNA A-to-I editing events in the alternative splicing sites for LURAP1 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for LURAP1 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for LURAP1 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for LURAP1 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_120240 | chr1_46220453_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-340-3p | chr1 | 46220447 | 46220453 | 7mer-m8 | 46220433 | 46220454 | 146 | -18.54 |
| ADediting_120240 | chr1_46220453_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-6827-3p | chr1 | 46220447 | 46220453 | 7mer-m8 | 46220434 | 46220454 | 140 | -14.58 |
| ADediting_120241 | chr1_46220469_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-196a-3p | chr1 | 46220464 | 46220470 | 7mer-m8 | 46220449 | 46220471 | 151 | -16.17 |
| ADediting_120242 | chr1_46220474_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-1343-3p | chr1 | 46220469 | 46220475 | 7mer-m8 | 46220454 | 46220476 | 146 | -16.62 |
| ADediting_120242 | chr1_46220474_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-6742-3p | chr1 | 46220468 | 46220475 | 8mer-1a | 46220456 | 46220475 | 140 | -14.83 |
| ADediting_120242 | chr1_46220474_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-6783-3p | chr1 | 46220469 | 46220475 | 7mer-m8 | 46220455 | 46220476 | 140 | -14.55 |
| ADediting_120242 | chr1_46220474_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-6861-5p | chr1 | 46220467 | 46220473 | 7mer-m8 | 46220449 | 46220474 | 145 | -22.37 |
| ADediting_120245 | chr1_46220494_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-591 | chr1 | 46220489 | 46220496 | 8mer-1a | 46220475 | 46220496 | 145 | -18.83 |
| ADediting_120245 | chr1_46220494_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-6808-3p | chr1 | 46220492 | 46220498 | 7mer-m8 | 46220480 | 46220499 | 157 | -20.96 |
| ADediting_120245 | chr1_46220494_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-6872-3p | chr1 | 46220487 | 46220493 | 7mer-m8 | 46220475 | 46220494 | 148 | -18.7 |
| ADediting_120251 | chr1_46220530_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-1199-5p | chr1 | 46220523 | 46220529 | 7mer-m8 | 46220511 | 46220530 | 156 | -29.47 |
| ADediting_120251 | chr1_46220530_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-6078 | chr1 | 46220526 | 46220533 | 8mer-1a | 46220514 | 46220533 | 152 | -22.59 |
| ADediting_120251 | chr1_46220530_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-6751-3p | chr1 | 46220523 | 46220529 | 7mer-m8 | 46220510 | 46220530 | 141 | -13.5 |
| ADediting_120255 | chr1_46220650_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-3940-3p | chr1 | 46220647 | 46220653 | 7mer-m8 | 46220631 | 46220654 | 146 | -22.05 |
| ADediting_120258 | chr1_46220676_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-1199-5p | chr1 | 46220669 | 46220675 | 7mer-m8 | 46220657 | 46220676 | 156 | -28.57 |
| ADediting_120258 | chr1_46220676_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-125a-5p | chr1 | 46220671 | 46220677 | 7mer-m8 | 46220655 | 46220678 | 147 | -22.65 |
| ADediting_120258 | chr1_46220676_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-125b-5p | chr1 | 46220671 | 46220677 | 7mer-m8 | 46220657 | 46220678 | 150 | -22.71 |
| ADediting_120258 | chr1_46220676_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-331-3p | chr1 | 46220673 | 46220679 | 7mer-1a | 46220659 | 46220679 | 145 | -25.53 |
| ADediting_120258 | chr1_46220676_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-4319 | chr1 | 46220671 | 46220677 | 7mer-m8 | 46220662 | 46220678 | 149 | -21.73 |
| ADediting_120258 | chr1_46220676_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-6751-3p | chr1 | 46220669 | 46220675 | 7mer-m8 | 46220656 | 46220676 | 141 | -13.15 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_120240 | chr1_46220453_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-10a-5p | chr1 | 46220450 | 46220456 | 7mer-m8 | 46220437 | 46220457 | 142 | -12.48 |
| ADediting_120240 | chr1_46220453_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-10b-5p | chr1 | 46220450 | 46220456 | 7mer-m8 | 46220431 | 46220457 | 144 | -12.24 |
| ADediting_120240 | chr1_46220453_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-339-5p | chr1 | 46220449 | 46220455 | 7mer-m8 | 46220435 | 46220456 | 151 | -17.78 |
| ADediting_120240 | chr1_46220453_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-4725-5p | chr1 | 46220451 | 46220457 | 7mer-m8 | 46220438 | 46220458 | 140 | -16.24 |
| ADediting_120240 | chr1_46220453_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-504-5p | chr1 | 46220451 | 46220457 | 7mer-m8 | 46220439 | 46220458 | 147 | -18.15 |
| ADediting_120240 | chr1_46220453_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-5699-3p | chr1 | 46220448 | 46220454 | 7mer-m8 | 46220434 | 46220455 | 141 | -16.39 |
| ADediting_120242 | chr1_46220474_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-6774-5p | chr1 | 46220469 | 46220475 | 7mer-1a | 46220447 | 46220475 | 141 | -31.28 |
| ADediting_120246 | chr1_46220499_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-4679 | chr1 | 46220493 | 46220499 | 7mer-m8 | 46220479 | 46220500 | 145 | -15.98 |
| ADediting_120248 | chr1_46220509_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-17-3p | chr1 | 46220503 | 46220509 | 7mer-m8 | 46220489 | 46220510 | 150 | -16.44 |
| ADediting_120253 | chr1_46220569_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-6811-3p | chr1 | 46220567 | 46220574 | 8mer-1a | 46220554 | 46220574 | 150 | -18.56 |
| ADediting_120254 | chr1_46220630_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-454-5p | chr1 | 46220626 | 46220632 | 7mer-m8 | 46220612 | 46220633 | 145 | -15.63 |
| ADediting_120254 | chr1_46220630_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-652-5p | chr1 | 46220628 | 46220634 | 7mer-m8 | 46220611 | 46220635 | 140 | -11.21 |
| ADediting_120255 | chr1_46220650_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-5189-5p | chr1 | 46220644 | 46220650 | 7mer-m8 | 46220627 | 46220651 | 151 | -22.48 |
| ADediting_120255 | chr1_46220650_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-612 | chr1 | 46220644 | 46220650 | 7mer-m8 | 46220627 | 46220651 | 150 | -25.24 |
| ADediting_120255 | chr1_46220650_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-661 | chr1 | 46220646 | 46220652 | 7mer-m8 | 46220628 | 46220653 | 142 | -20.62 |
| ADediting_120255 | chr1_46220650_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-6860 | chr1 | 46220644 | 46220650 | 7mer-m8 | 46220631 | 46220651 | 150 | -21.8 |
| ADediting_120255 | chr1_46220650_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-939-3p | chr1 | 46220645 | 46220651 | 7mer-m8 | 46220632 | 46220652 | 140 | -15.63 |
| ADediting_120257 | chr1_46220675_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-623 | chr1 | 46220673 | 46220679 | 7mer-m8 | 46220656 | 46220680 | 148 | -27.2 |
| ADediting_120258 | chr1_46220676_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-188-5p | chr1 | 46220674 | 46220680 | 7mer-m8 | 46220661 | 46220681 | 151 | -19.52 |
| ADediting_120258 | chr1_46220676_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-623 | chr1 | 46220673 | 46220679 | 7mer-m8 | 46220656 | 46220680 | 148 | -27.2 |
| ADediting_120258 | chr1_46220676_+ | ENSG00000171357.6 | ENST00000371980.4 | LURAP1-201 | hsa-miR-6866-3p | chr1 | 46220674 | 46220680 | 7mer-m8 | 46220660 | 46220681 | 145 | -19.09 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for LURAP1 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000371980.4 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_120240 | ENST00000371980.4 | chr1_46220453_+ | 1046 | -696.50 | -697.20 | -714.50 |
| ADediting_120241 | ENST00000371980.4 | chr1_46220469_+ | 1062 | -697.50 | -697.20 | -714.50 |
| ADediting_120242 | ENST00000371980.4 | chr1_46220474_+ | 1067 | -699.10 | -697.20 | -714.50 |
| ADediting_120243 | ENST00000371980.4 | chr1_46220478_+ | 1071 | -697.10 | -697.20 | -714.50 |
| ADediting_120244 | ENST00000371980.4 | chr1_46220491_+ | 1084 | -698.70 | -697.20 | -714.50 |
| ADediting_120245 | ENST00000371980.4 | chr1_46220494_+ | 1087 | -698.60 | -697.20 | -714.50 |
| ADediting_120246 | ENST00000371980.4 | chr1_46220499_+ | 1092 | -696.50 | -697.20 | -714.50 |
| ADediting_120247 | ENST00000371980.4 | chr1_46220504_+ | 1097 | -699.50 | -697.20 | -714.50 |
| ADediting_120248 | ENST00000371980.4 | chr1_46220509_+ | 1102 | -697.10 | -697.20 | -714.50 |
| ADediting_120249 | ENST00000371980.4 | chr1_46220516_+ | 1109 | -699.00 | -697.20 | -714.50 |
| ADediting_120250 | ENST00000371980.4 | chr1_46220529_+ | 1122 | -697.90 | -697.20 | -714.50 |
| ADediting_120251 | ENST00000371980.4 | chr1_46220530_+ | 1123 | -703.30 | -697.20 | -714.50 |
| ADediting_120252 | ENST00000371980.4 | chr1_46220563_+ | 1156 | -700.40 | -697.20 | -714.50 |
| ADediting_120253 | ENST00000371980.4 | chr1_46220569_+ | 1162 | -696.90 | -697.20 | -714.50 |
| ADediting_120254 | ENST00000371980.4 | chr1_46220630_+ | 1223 | -697.40 | -697.20 | -714.50 |
| ADediting_120255 | ENST00000371980.4 | chr1_46220650_+ | 1243 | -696.50 | -697.20 | -714.50 |
| ADediting_120256 | ENST00000371980.4 | chr1_46220661_+ | 1254 | -697.20 | -697.20 | -714.50 |
| ADediting_120257 | ENST00000371980.4 | chr1_46220675_+ | 1268 | -700.60 | -697.20 | -714.50 |
| ADediting_120258 | ENST00000371980.4 | chr1_46220676_+ | 1269 | -699.10 | -697.20 | -714.50 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for LURAP1 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_120243 | chr1_46220478_+ | 0.182424234276853 | 0.109454012162718 | 0.000112608137536235 | 0.31009093603152 | 0.0152586329594207 | 0.197790386515414 |
| CER | ADediting_120252 | chr1_46220563_+ | 0.000332659738253578 | 0.289130547687316 | 5.71388240601706e-10 | 0.47883352393193 | 0.00161258545785064 | 0.255345786019546 |
| CER | ADediting_120253 | chr1_46220569_+ | 0.0266983036497879 | 0.180945048668658 | 4.67688399854047e-07 | 0.397671256445882 | 0.0175128269503267 | 0.193758910815906 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 7.25772572523219e-48 | 0.704920568553874 | 3.33948854534297e-33 | 0.611687271989336 | 1.91221325881772e-17 | 0.457544977343634 |
| AC | 4.41688826355377e-11 | 0.401126286384958 | 7.71533661541464e-13 | 0.43286342469451 | 0.178356779462879 | 0.085390268935994 |
| PCC | 2.83261027319811e-20 | 0.602727911766899 | 2.68078759233792e-21 | 0.615496396441006 | 0.000342835615439433 | 0.256419409384654 |
| CER | 4.71660751839175e-52 | 0.8889554646692 | 1.26694471540984e-32 | 0.785290177517276 | 0.00855698690282603 | 0.213976178162217 |
| TCX | 1.05035825319498e-19 | 0.654520784100522 | 0.0015076049057943 | 0.256878974788083 | 1.58702305267446e-15 | 0.59150366129722 |
| FP | 4.02080318518906e-35 | 0.762557475922865 | 1.21343978915432e-20 | 0.62455433733012 | 6.66035359605781e-12 | 0.48525711557133 |
| IFG | 8.28772077639786e-05 | 0.70509169738089 | 0.00178084374333022 | 0.593067156882151 | 0.00413927220615915 | 0.553040165673004 |
| PG | 3.21764859864391e-30 | 0.71331651349096 | 4.21624405859283e-25 | 0.664922087411368 | 0.019178429913726 | 0.171607973693088 |
| STG | 4.28396376955712e-17 | 0.76126537968338 | 1.97821819779522e-11 | 0.651258139604815 | 0.000279589733396797 | 0.386702233676023 |
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Relation with AD stages for LURAP1 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_120252 | chr1_46220563_+ | 0.00013705105125726 | 0.358824653861745 |
| CER | ADediting_120253 | chr1_46220569_+ | 0.00134940512597681 | 0.304606774043601 |
| TCX | ADediting_120252 | chr1_46220563_+ | 0.000772167459207462 | 0.32169048169233 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 0.000231004460506591 | 0.34728963058556 |
| TCX | 7.12926919697342e-07 | 0.459752651147605 |
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RelatedDrugs for LURAP1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for LURAP1 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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