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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for LURAP1 |
 Gene summary |
| Gene information | Gene symbol | LURAP1 | Gene ID | 541468 |
| Gene name | leucine rich adaptor protein 1 | |
| Synonyms | C1orf190|LRAP35a|LRP35A | |
| Cytomap | 1p34.1 | |
| Type of gene | protein-coding | |
| Description | leucine rich adaptor protein 1NF-kappa-B activator C1orf190leucine repeat adapter protein 35Aleucine repeat adaptor protein 35a | |
| Modification date | 20200313 | |
| UniProtAcc | Q96LR2, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| LURAP1 | GO:0001819 | positive regulation of cytokine production | 21048106 |
| LURAP1 | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling | 21048106 |
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RNA A-to-I events for LURAP1 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_120240(46220453, +), ADediting_120241(46220469, +), ADediting_120242(46220474, +), ADediting_120243(46220478, +), ADediting_120244(46220491, +), ADediting_120245(46220494, +), ADediting_120246(46220499, +), ADediting_120247(46220504, +), ADediting_120248(46220509, +), ADediting_120249(46220516, +), ADediting_120250(46220529, +), ADediting_120251(46220530, +), ADediting_120252(46220563, +), ADediting_120253(46220569, +), ADediting_120254(46220630, +), ADediting_120255(46220650, +), ADediting_120256(46220661, +), ADediting_120257(46220675, +), ADediting_120258(46220676, +), |
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RNA editing positional annotations for LURAP1 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_120240 | chr1_46220453_+ | UTR3 |
| ADediting_120241 | chr1_46220469_+ | UTR3 |
| ADediting_120242 | chr1_46220474_+ | UTR3 |
| ADediting_120243 | chr1_46220478_+ | UTR3 |
| ADediting_120244 | chr1_46220491_+ | UTR3 |
| ADediting_120245 | chr1_46220494_+ | UTR3 |
| ADediting_120246 | chr1_46220499_+ | UTR3 |
| ADediting_120247 | chr1_46220504_+ | UTR3 |
| ADediting_120248 | chr1_46220509_+ | UTR3 |
| ADediting_120249 | chr1_46220516_+ | UTR3 |
| ADediting_120250 | chr1_46220529_+ | UTR3 |
| ADediting_120251 | chr1_46220530_+ | UTR3 |
| ADediting_120252 | chr1_46220563_+ | UTR3 |
| ADediting_120253 | chr1_46220569_+ | UTR3 |
| ADediting_120254 | chr1_46220630_+ | UTR3 |
| ADediting_120255 | chr1_46220650_+ | UTR3 |
| ADediting_120256 | chr1_46220661_+ | UTR3 |
| ADediting_120257 | chr1_46220675_+ | UTR3 |
| ADediting_120258 | chr1_46220676_+ | UTR3 |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_120240 | chr1_46220453_+ | SINE | Alu | Name=AluJb |
| ADediting_120241 | chr1_46220469_+ | SINE | Alu | Name=AluJb |
| ADediting_120242 | chr1_46220474_+ | SINE | Alu | Name=AluJb |
| ADediting_120243 | chr1_46220478_+ | SINE | Alu | Name=AluJb |
| ADediting_120244 | chr1_46220491_+ | SINE | Alu | Name=AluJb |
| ADediting_120245 | chr1_46220494_+ | SINE | Alu | Name=AluJb |
| ADediting_120246 | chr1_46220499_+ | SINE | Alu | Name=AluJb |
| ADediting_120247 | chr1_46220504_+ | SINE | Alu | Name=AluJb |
| ADediting_120248 | chr1_46220509_+ | SINE | Alu | Name=AluJb |
| ADediting_120249 | chr1_46220516_+ | SINE | Alu | Name=AluJb |
| ADediting_120250 | chr1_46220529_+ | SINE | Alu | Name=AluJb |
| ADediting_120251 | chr1_46220530_+ | SINE | Alu | Name=AluJb |
| ADediting_120252 | chr1_46220563_+ | SINE | Alu | Name=AluJb |
| ADediting_120253 | chr1_46220569_+ | SINE | Alu | Name=AluJb |
| ADediting_120254 | chr1_46220630_+ | SINE | Alu | Name=AluJb |
| ADediting_120255 | chr1_46220650_+ | SINE | Alu | Name=AluJb |
| ADediting_120256 | chr1_46220661_+ | SINE | Alu | Name=AluJb |
| ADediting_120257 | chr1_46220675_+ | SINE | Alu | Name=AluJb |
| ADediting_120258 | chr1_46220676_+ | SINE | Alu | Name=AluJb |
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RNA A-to-I editing events in the alternative splicing sites for LURAP1 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for LURAP1 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |