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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for PMS2 |
 Gene summary |
| Gene information | Gene symbol | PMS2 | Gene ID | 5395 |
| Gene name | PMS1 homolog 2, mismatch repair system component | |
| Synonyms | HNPCC4|MLH4|PMS2CL|PMSL2 | |
| Cytomap | 7p22.1 | |
| Type of gene | protein-coding | |
| Description | mismatch repair endonuclease PMS2DNA mismatch repair protein PMS2PMS1 homolog 2, mismatch repair proteinPMS1 protein homolog 2PMS2 postmeiotic segregation increased 2postmeiotic segregation increased 2 nirs variant 6 | |
| Modification date | 20200327 | |
| UniProtAcc | P54278, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| PMS2 | GO:0006298 | mismatch repair | 10871409|23709753 |
Top |
RNA A-to-I events for PMS2 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_1341799(5971772, -), ADediting_1341800(5971814, -), ADediting_1341801(5971826, -), ADediting_1341802(5971839, -), ADediting_1341803(5971868, -), ADediting_1341804(5971930, -), ADediting_1341805(5971935, -), ADediting_1341806(5971947, -), ADediting_1341807(5971948, -), ADediting_1341808(5971954, -), ADediting_1341809(5971978, -), ADediting_1341810(5971989, -), ADediting_1341811(5972915, -), ADediting_1341812(5972940, -), ADediting_1341813(5972941, -), ADediting_1341814(5972949, -), ADediting_1341815(5972955, -), ADediting_1341816(5972968, -), ADediting_1341817(5973019, -), ADediting_1341818(5973020, -), ADediting_1341819(5973021, -), ADediting_1341820(5973022, -), ADediting_1341821(5973025, -), ADediting_1341822(5973036, -), ADediting_1341823(5973037, -), ADediting_1341824(5973040, -), ADediting_1341825(5973044, -), ADediting_1341826(5973046, -), ADediting_1341827(5973050, -), ADediting_1341828(5973056, -), ADediting_1341829(5973061, -), ADediting_1341830(5973067, -), ADediting_1341831(5973068, -), ADediting_1341832(5973070, -), ADediting_1341833(5973075, -), ADediting_1341834(5973080, -), ADediting_1341835(5975996, -), ADediting_1341836(5977193, -), ADediting_1341837(5977195, -), ADediting_1341838(5977863, -), ADediting_1341839(5977876, -), ADediting_1341840(5977885, -), ADediting_1341841(5977930, -), ADediting_1341842(5978936, -), ADediting_1341843(5978938, -), ADediting_1341844(5978950, -), ADediting_1341845(5978977, -), ADediting_1341846(5978978, -), ADediting_1341847(5978990, -), ADediting_1341848(5978992, -), ADediting_1341849(5979003, -), ADediting_1341850(5979040, -), ADediting_1341851(5979112, -), ADediting_1341852(5979263, -), ADediting_1341853(5982344, -), ADediting_1341854(5982370, -), ADediting_1341855(5982476, -), ADediting_1341856(5982609, -), ADediting_1341857(5982616, -), ADediting_1341858(5984555, -), ADediting_1341859(5984566, -), ADediting_1341860(5984676, -), ADediting_1341861(5984703, -), ADediting_1341862(5984722, -), ADediting_1341863(5984733, -), ADediting_1341864(5984741, -), ADediting_1341865(5984771, -), ADediting_1341866(5985333, -), ADediting_1341867(5986658, -), ADediting_1341868(5988924, -), ADediting_1341869(5990110, -), ADediting_1341870(5990172, -), ADediting_1341871(5990281, -), ADediting_1341872(5990779, -), ADediting_1341873(5992204, -), ADediting_1341874(5992270, -), ADediting_1341875(5992348, -), ADediting_1341876(5992374, -), ADediting_1341877(5992387, -), ADediting_1341878(5992388, -), ADediting_1341879(5992405, -), ADediting_1341880(5992417, -), ADediting_1341881(5992422, -), ADediting_1341882(5992457, -), ADediting_1341883(5992458, -), ADediting_1341884(5992508, -), ADediting_1341885(5992513, -), ADediting_1341886(5992521, -), ADediting_1341887(5992533, -), ADediting_1341888(5992592, -), ADediting_1341889(5992593, -), ADediting_1341890(5992595, -), ADediting_1341891(5993174, -), ADediting_1341892(5993213, -), ADediting_1341893(5993285, -), ADediting_1341894(5993288, -), ADediting_1341895(5993333, -), ADediting_1341896(5993340, -), ADediting_1341897(5993745, -), ADediting_1341898(5993823, -), ADediting_1341899(5994124, -), ADediting_1341900(5994126, -), ADediting_1341901(5994200, -), ADediting_1341902(5994214, -), ADediting_1341903(5994217, -), ADediting_1341904(5994259, -), ADediting_1341906(5994269, -), ADediting_1341907(5994272, -), ADediting_1341908(5994281, -), ADediting_1341909(5994298, -), ADediting_1341910(5994304, -), ADediting_1341911(5994324, -), ADediting_1341912(5994544, -), ADediting_1341913(5994584, -), ADediting_1341914(5994609, -), ADediting_1341915(5994615, -), ADediting_1341916(5994654, -), ADediting_1341917(5994664, -), ADediting_1341918(5994719, -), ADediting_1341919(5994754, -), ADediting_1341920(5994773, -), ADediting_1341921(5995071, -), ADediting_1341922(5995095, -), ADediting_1341923(5995110, -), ADediting_1341924(5995111, -), ADediting_1341925(5995114, -), ADediting_1341926(5995134, -), ADediting_1341927(5995135, -), ADediting_1341928(5995140, -), ADediting_1341929(5995146, -), ADediting_1341930(5995149, -), ADediting_1341931(5995166, -), ADediting_1341932(5995170, -), ADediting_1341933(5995175, -), ADediting_1341934(5995176, -), ADediting_1341935(5995194, -), ADediting_1341936(5995198, -), ADediting_1341937(5995201, -), ADediting_1341938(5995219, -), ADediting_1341939(5995240, -), ADediting_1341940(5995241, -), ADediting_1341941(5995269, -), ADediting_1341942(5995304, -), ADediting_1341943(5995309, -), ADediting_1341944(5995310, -), ADediting_1341945(5995326, -), ADediting_1341946(5996324, -), ADediting_1341947(5996433, -), ADediting_1341948(5998142, -), ADediting_1341949(5998277, -), ADediting_1341950(5998317, -), ADediting_1341951(5998448, -), ADediting_1341952(5998582, -), ADediting_1341953(5998599, -), ADediting_1341954(5998608, -), ADediting_1341955(5998810, -), ADediting_1341956(5998904, -), ADediting_1341957(5998907, -), ADediting_1341958(6001433, -), ADediting_1341959(6001482, -), ADediting_1341960(6001486, -), ADediting_1341961(6001509, -), ADediting_1341962(6001597, -), ADediting_1341963(6001727, -), ADediting_1341964(6001739, -), ADediting_1341965(6001754, -), ADediting_1341966(6001844, -), ADediting_1341967(6001893, -), ADediting_1341968(6001910, -), ADediting_1341969(6001930, -), ADediting_1341970(6004471, -), ADediting_1341971(6005278, -), ADediting_1341972(6006407, -), ADediting_1341973(6006434, -), ADediting_1341974(6006486, -), ADediting_1341975(6006531, -), ADediting_1341976(6006537, -), ADediting_1341977(6006541, -), ADediting_1341978(6006570, -), ADediting_1341979(6006606, -), ADediting_1341980(6008024, -), ADediting_1587918(5971882, -), ADediting_1587919(5995153, -), ADediting_1666269(5990201, -), |
Top |
RNA editing positional annotations for PMS2 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_1341799 | chr7_5971772_- | UTR3 |
| ADediting_1341800 | chr7_5971814_- | UTR3 |
| ADediting_1341801 | chr7_5971826_- | UTR3 |
| ADediting_1341802 | chr7_5971839_- | UTR3 |
| ADediting_1341803 | chr7_5971868_- | UTR3 |
| ADediting_1341804 | chr7_5971930_- | UTR3 |
| ADediting_1341805 | chr7_5971935_- | UTR3 |
| ADediting_1341806 | chr7_5971947_- | UTR3 |
| ADediting_1341807 | chr7_5971948_- | UTR3 |
| ADediting_1341808 | chr7_5971954_- | UTR3 |
| ADediting_1341809 | chr7_5971978_- | UTR3 |
| ADediting_1341810 | chr7_5971989_- | UTR3 |
| ADediting_1341811 | chr7_5972915_- | UTR3 |
| ADediting_1341812 | chr7_5972940_- | UTR3 |
| ADediting_1341813 | chr7_5972941_- | UTR3 |
| ADediting_1341814 | chr7_5972949_- | UTR3 |
| ADediting_1341815 | chr7_5972955_- | UTR3 |
| ADediting_1341816 | chr7_5972968_- | UTR3 |
| ADediting_1341817 | chr7_5973019_- | UTR3 |
| ADediting_1341818 | chr7_5973020_- | UTR3 |
| ADediting_1341819 | chr7_5973021_- | UTR3 |
| ADediting_1341820 | chr7_5973022_- | UTR3 |
| ADediting_1341821 | chr7_5973025_- | UTR3 |
| ADediting_1341822 | chr7_5973036_- | UTR3 |
| ADediting_1341823 | chr7_5973037_- | UTR3 |
| ADediting_1341824 | chr7_5973040_- | UTR3 |
| ADediting_1341825 | chr7_5973044_- | UTR3 |
| ADediting_1341826 | chr7_5973046_- | UTR3 |
| ADediting_1341827 | chr7_5973050_- | UTR3 |
| ADediting_1341828 | chr7_5973056_- | UTR3 |
| ADediting_1341829 | chr7_5973061_- | UTR3 |
| ADediting_1341830 | chr7_5973067_- | UTR3 |
| ADediting_1341831 | chr7_5973068_- | UTR3 |
| ADediting_1341832 | chr7_5973070_- | UTR3 |
| ADediting_1341833 | chr7_5973075_- | UTR3 |
| ADediting_1341834 | chr7_5973080_- | UTR3 |
| ADediting_1341835 | chr7_5975996_- | intronic |
| ADediting_1341836 | chr7_5977193_- | intronic |
| ADediting_1341837 | chr7_5977195_- | intronic |
| ADediting_1341838 | chr7_5977863_- | intronic |
| ADediting_1341839 | chr7_5977876_- | intronic |
| ADediting_1341840 | chr7_5977885_- | intronic |
| ADediting_1341841 | chr7_5977930_- | intronic |
| ADediting_1341842 | chr7_5978936_- | intronic |
| ADediting_1341843 | chr7_5978938_- | intronic |
| ADediting_1341844 | chr7_5978950_- | intronic |
| ADediting_1341845 | chr7_5978977_- | intronic |
| ADediting_1341846 | chr7_5978978_- | intronic |
| ADediting_1341847 | chr7_5978990_- | intronic |
| ADediting_1341848 | chr7_5978992_- | intronic |
| ADediting_1341849 | chr7_5979003_- | intronic |
| ADediting_1341850 | chr7_5979040_- | intronic |
| ADediting_1341851 | chr7_5979112_- | intronic |
| ADediting_1341852 | chr7_5979263_- | intronic |
| ADediting_1341853 | chr7_5982344_- | intronic |
| ADediting_1341854 | chr7_5982370_- | intronic |
| ADediting_1341855 | chr7_5982476_- | intronic |
| ADediting_1341856 | chr7_5982609_- | intronic |
| ADediting_1341857 | chr7_5982616_- | intronic |
| ADediting_1341858 | chr7_5984555_- | intronic |
| ADediting_1341859 | chr7_5984566_- | intronic |
| ADediting_1341860 | chr7_5984676_- | intronic |
| ADediting_1341861 | chr7_5984703_- | intronic |
| ADediting_1341862 | chr7_5984722_- | intronic |
| ADediting_1341863 | chr7_5984733_- | intronic |
| ADediting_1341864 | chr7_5984741_- | intronic |
| ADediting_1341865 | chr7_5984771_- | intronic |
| ADediting_1341866 | chr7_5985333_- | intronic |
| ADediting_1341867 | chr7_5986658_- | intronic |
| ADediting_1341868 | chr7_5988924_- | intronic |
| ADediting_1341869 | chr7_5990110_- | intronic |
| ADediting_1341870 | chr7_5990172_- | intronic |
| ADediting_1341871 | chr7_5990281_- | intronic |
| ADediting_1341872 | chr7_5990779_- | intronic |
| ADediting_1341873 | chr7_5992204_- | intronic |
| ADediting_1341874 | chr7_5992270_- | intronic |
| ADediting_1341875 | chr7_5992348_- | intronic |
| ADediting_1341876 | chr7_5992374_- | intronic |
| ADediting_1341877 | chr7_5992387_- | intronic |
| ADediting_1341878 | chr7_5992388_- | intronic |
| ADediting_1341879 | chr7_5992405_- | intronic |
| ADediting_1341880 | chr7_5992417_- | intronic |
| ADediting_1341881 | chr7_5992422_- | intronic |
| ADediting_1341882 | chr7_5992457_- | intronic |
| ADediting_1341883 | chr7_5992458_- | intronic |
| ADediting_1341884 | chr7_5992508_- | intronic |
| ADediting_1341885 | chr7_5992513_- | intronic |
| ADediting_1341886 | chr7_5992521_- | intronic |
| ADediting_1341887 | chr7_5992533_- | intronic |
| ADediting_1341888 | chr7_5992592_- | intronic |
| ADediting_1341889 | chr7_5992593_- | intronic |
| ADediting_1341890 | chr7_5992595_- | intronic |
| ADediting_1341891 | chr7_5993174_- | intronic |
| ADediting_1341892 | chr7_5993213_- | intronic |
| ADediting_1341893 | chr7_5993285_- | intronic |
| ADediting_1341894 | chr7_5993288_- | intronic |
| ADediting_1341895 | chr7_5993333_- | intronic |
| ADediting_1341896 | chr7_5993340_- | intronic |
| ADediting_1341897 | chr7_5993745_- | intronic |
| ADediting_1341898 | chr7_5993823_- | intronic |
| ADediting_1341899 | chr7_5994124_- | intronic |
| ADediting_1341900 | chr7_5994126_- | intronic |
| ADediting_1341901 | chr7_5994200_- | intronic |
| ADediting_1341902 | chr7_5994214_- | intronic |
| ADediting_1341903 | chr7_5994217_- | intronic |
| ADediting_1341904 | chr7_5994259_- | intronic |
| ADediting_1341906 | chr7_5994269_- | intronic |
| ADediting_1341907 | chr7_5994272_- | intronic |
| ADediting_1341908 | chr7_5994281_- | intronic |
| ADediting_1341909 | chr7_5994298_- | intronic |
| ADediting_1341910 | chr7_5994304_- | intronic |
| ADediting_1341911 | chr7_5994324_- | intronic |
| ADediting_1341912 | chr7_5994544_- | intronic |
| ADediting_1341913 | chr7_5994584_- | intronic |
| ADediting_1341914 | chr7_5994609_- | intronic |
| ADediting_1341915 | chr7_5994615_- | intronic |
| ADediting_1341916 | chr7_5994654_- | intronic |
| ADediting_1341917 | chr7_5994664_- | intronic |
| ADediting_1341918 | chr7_5994719_- | intronic |
| ADediting_1341919 | chr7_5994754_- | intronic |
| ADediting_1341920 | chr7_5994773_- | intronic |
| ADediting_1341921 | chr7_5995071_- | intronic |
| ADediting_1341922 | chr7_5995095_- | intronic |
| ADediting_1341923 | chr7_5995110_- | intronic |
| ADediting_1341924 | chr7_5995111_- | intronic |
| ADediting_1341925 | chr7_5995114_- | intronic |
| ADediting_1341926 | chr7_5995134_- | intronic |
| ADediting_1341927 | chr7_5995135_- | intronic |
| ADediting_1341928 | chr7_5995140_- | intronic |
| ADediting_1341929 | chr7_5995146_- | intronic |
| ADediting_1341930 | chr7_5995149_- | intronic |
| ADediting_1341931 | chr7_5995166_- | intronic |
| ADediting_1341932 | chr7_5995170_- | intronic |
| ADediting_1341933 | chr7_5995175_- | intronic |
| ADediting_1341934 | chr7_5995176_- | intronic |
| ADediting_1341935 | chr7_5995194_- | intronic |
| ADediting_1341936 | chr7_5995198_- | intronic |
| ADediting_1341937 | chr7_5995201_- | intronic |
| ADediting_1341938 | chr7_5995219_- | intronic |
| ADediting_1341939 | chr7_5995240_- | intronic |
| ADediting_1341940 | chr7_5995241_- | intronic |
| ADediting_1341941 | chr7_5995269_- | intronic |
| ADediting_1341942 | chr7_5995304_- | intronic |
| ADediting_1341943 | chr7_5995309_- | intronic |
| ADediting_1341944 | chr7_5995310_- | intronic |
| ADediting_1341945 | chr7_5995326_- | intronic |
| ADediting_1341946 | chr7_5996324_- | intronic |
| ADediting_1341947 | chr7_5996433_- | intronic |
| ADediting_1341948 | chr7_5998142_- | intronic |
| ADediting_1341949 | chr7_5998277_- | intronic |
| ADediting_1341950 | chr7_5998317_- | intronic |
| ADediting_1341951 | chr7_5998448_- | intronic |
| ADediting_1341952 | chr7_5998582_- | intronic |
| ADediting_1341953 | chr7_5998599_- | intronic |
| ADediting_1341954 | chr7_5998608_- | intronic |
| ADediting_1341955 | chr7_5998810_- | intronic |
| ADediting_1341956 | chr7_5998904_- | intronic |
| ADediting_1341957 | chr7_5998907_- | intronic |
| ADediting_1341958 | chr7_6001433_- | intronic |
| ADediting_1341959 | chr7_6001482_- | intronic |
| ADediting_1341960 | chr7_6001486_- | intronic |
| ADediting_1341961 | chr7_6001509_- | intronic |
| ADediting_1341962 | chr7_6001597_- | intronic |
| ADediting_1341963 | chr7_6001727_- | intronic |
| ADediting_1341964 | chr7_6001739_- | intronic |
| ADediting_1341965 | chr7_6001754_- | intronic |
| ADediting_1341966 | chr7_6001844_- | intronic |
| ADediting_1341967 | chr7_6001893_- | intronic |
| ADediting_1341968 | chr7_6001910_- | intronic |
| ADediting_1341969 | chr7_6001930_- | intronic |
| ADediting_1341970 | chr7_6004471_- | intronic |
| ADediting_1341971 | chr7_6005278_- | intronic |
| ADediting_1341972 | chr7_6006407_- | intronic |
| ADediting_1341973 | chr7_6006434_- | intronic |
| ADediting_1341974 | chr7_6006486_- | intronic |
| ADediting_1341975 | chr7_6006531_- | intronic |
| ADediting_1341976 | chr7_6006537_- | intronic |
| ADediting_1341977 | chr7_6006541_- | intronic |
| ADediting_1341978 | chr7_6006570_- | intronic |
| ADediting_1341979 | chr7_6006606_- | intronic |
| ADediting_1341980 | chr7_6008024_- | intronic |
| ADediting_1587918 | chr7_5971882_- | UTR3 |
| ADediting_1587919 | chr7_5995153_- | intronic |
| ADediting_1666269 | chr7_5990201_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_1341799 | chr7_5971772_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341800 | chr7_5971814_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341801 | chr7_5971826_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341802 | chr7_5971839_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341803 | chr7_5971868_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341804 | chr7_5971930_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341805 | chr7_5971935_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341806 | chr7_5971947_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341807 | chr7_5971948_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341808 | chr7_5971954_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341809 | chr7_5971978_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341810 | chr7_5971989_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341811 | chr7_5972915_- | SINE | Alu | Name=AluSx |
| ADediting_1341812 | chr7_5972940_- | SINE | Alu | Name=AluSx |
| ADediting_1341813 | chr7_5972941_- | SINE | Alu | Name=AluSx |
| ADediting_1341814 | chr7_5972949_- | SINE | Alu | Name=AluSx |
| ADediting_1341815 | chr7_5972955_- | SINE | Alu | Name=AluSx |
| ADediting_1341816 | chr7_5972968_- | SINE | Alu | Name=AluSx |
| ADediting_1341817 | chr7_5973019_- | SINE | Alu | Name=AluSx |
| ADediting_1341818 | chr7_5973020_- | SINE | Alu | Name=AluSx |
| ADediting_1341819 | chr7_5973021_- | SINE | Alu | Name=AluSx |
| ADediting_1341820 | chr7_5973022_- | SINE | Alu | Name=AluSx |
| ADediting_1341821 | chr7_5973025_- | SINE | Alu | Name=AluSx |
| ADediting_1341822 | chr7_5973036_- | SINE | Alu | Name=AluSx |
| ADediting_1341823 | chr7_5973037_- | SINE | Alu | Name=AluSx |
| ADediting_1341824 | chr7_5973040_- | SINE | Alu | Name=AluSx |
| ADediting_1341825 | chr7_5973044_- | SINE | Alu | Name=AluSx |
| ADediting_1341826 | chr7_5973046_- | SINE | Alu | Name=AluSx |
| ADediting_1341827 | chr7_5973050_- | SINE | Alu | Name=AluSx |
| ADediting_1341828 | chr7_5973056_- | SINE | Alu | Name=AluSx |
| ADediting_1341829 | chr7_5973061_- | SINE | Alu | Name=AluSx |
| ADediting_1341830 | chr7_5973067_- | SINE | Alu | Name=AluSx |
| ADediting_1341831 | chr7_5973068_- | SINE | Alu | Name=AluSx |
| ADediting_1341832 | chr7_5973070_- | SINE | Alu | Name=AluSx |
| ADediting_1341833 | chr7_5973075_- | SINE | Alu | Name=AluSx |
| ADediting_1341834 | chr7_5973080_- | SINE | Alu | Name=AluSx |
| ADediting_1341835 | chr7_5975996_- | SINE | Alu | Name=AluSg |
| ADediting_1341836 | chr7_5977193_- | SINE | Alu | Name=AluYm1 |
| ADediting_1341837 | chr7_5977195_- | SINE | Alu | Name=AluYm1 |
| ADediting_1341838 | chr7_5977863_- | SINE | Alu | Name=AluY |
| ADediting_1341839 | chr7_5977876_- | SINE | Alu | Name=AluY |
| ADediting_1341840 | chr7_5977885_- | SINE | Alu | Name=AluY |
| ADediting_1341841 | chr7_5977930_- | SINE | Alu | Name=AluY |
| ADediting_1341842 | chr7_5978936_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341843 | chr7_5978938_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341844 | chr7_5978950_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341845 | chr7_5978977_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341846 | chr7_5978978_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341847 | chr7_5978990_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341848 | chr7_5978992_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341849 | chr7_5979003_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341850 | chr7_5979040_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341851 | chr7_5979112_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341852 | chr7_5979263_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341853 | chr7_5982344_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341854 | chr7_5982370_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341855 | chr7_5982476_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341856 | chr7_5982609_- | SINE | Alu | Name=AluSx |
| ADediting_1341857 | chr7_5982616_- | SINE | Alu | Name=AluSx |
| ADediting_1341858 | chr7_5984555_- | SINE | Alu | Name=AluSx1 |
| ADediting_1341859 | chr7_5984566_- | SINE | Alu | Name=AluSx1 |
| ADediting_1341860 | chr7_5984676_- | SINE | Alu | Name=AluSx1 |
| ADediting_1341861 | chr7_5984703_- | SINE | Alu | Name=AluSx1 |
| ADediting_1341862 | chr7_5984722_- | SINE | Alu | Name=AluSx1 |
| ADediting_1341863 | chr7_5984733_- | SINE | Alu | Name=AluSx1 |
| ADediting_1341864 | chr7_5984741_- | SINE | Alu | Name=AluSx1 |
| ADediting_1341865 | chr7_5984771_- | SINE | Alu | Name=AluSx1 |
| ADediting_1341866 | chr7_5985333_- | SINE | Alu | Name=AluJr |
| ADediting_1341867 | chr7_5986658_- | SINE | Alu | Name=AluSx |
| ADediting_1341868 | chr7_5988924_- | SINE | Alu | Name=AluY |
| ADediting_1341869 | chr7_5990110_- | SINE | Alu | Name=AluSz |
| ADediting_1341870 | chr7_5990172_- | SINE | Alu | Name=AluSz |
| ADediting_1341871 | chr7_5990281_- | SINE | Alu | Name=AluSz |
| ADediting_1341872 | chr7_5990779_- | SINE | Alu | Name=AluSx1 |
| ADediting_1341873 | chr7_5992204_- | SINE | Alu | Name=AluJb |
| ADediting_1341874 | chr7_5992270_- | SINE | Alu | Name=AluJb |
| ADediting_1341875 | chr7_5992348_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341876 | chr7_5992374_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341877 | chr7_5992387_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341878 | chr7_5992388_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341879 | chr7_5992405_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341880 | chr7_5992417_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341881 | chr7_5992422_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341882 | chr7_5992457_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341883 | chr7_5992458_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341884 | chr7_5992508_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341885 | chr7_5992513_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341886 | chr7_5992521_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341887 | chr7_5992533_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341888 | chr7_5992592_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341889 | chr7_5992593_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341890 | chr7_5992595_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341891 | chr7_5993174_- | SINE | Alu | Name=AluSx |
| ADediting_1341892 | chr7_5993213_- | SINE | Alu | Name=AluSx |
| ADediting_1341893 | chr7_5993285_- | SINE | Alu | Name=AluSx |
| ADediting_1341894 | chr7_5993288_- | SINE | Alu | Name=AluSx |
| ADediting_1341895 | chr7_5993333_- | SINE | Alu | Name=AluSx |
| ADediting_1341896 | chr7_5993340_- | SINE | Alu | Name=AluSx |
| ADediting_1341897 | chr7_5993745_- | SINE | Alu | Name=AluSx4 |
| ADediting_1341898 | chr7_5993823_- | SINE | Alu | Name=AluSx4 |
| ADediting_1341899 | chr7_5994124_- | SINE | Alu | Name=AluSg |
| ADediting_1341900 | chr7_5994126_- | SINE | Alu | Name=AluSg |
| ADediting_1341901 | chr7_5994200_- | SINE | Alu | Name=AluSg |
| ADediting_1341902 | chr7_5994214_- | SINE | Alu | Name=AluSg |
| ADediting_1341903 | chr7_5994217_- | SINE | Alu | Name=AluSg |
| ADediting_1341904 | chr7_5994259_- | SINE | Alu | Name=AluSg |
| ADediting_1341906 | chr7_5994269_- | SINE | Alu | Name=AluSg |
| ADediting_1341907 | chr7_5994272_- | SINE | Alu | Name=AluSg |
| ADediting_1341908 | chr7_5994281_- | SINE | Alu | Name=AluSg |
| ADediting_1341909 | chr7_5994298_- | SINE | Alu | Name=AluSg |
| ADediting_1341910 | chr7_5994304_- | SINE | Alu | Name=AluSg |
| ADediting_1341911 | chr7_5994324_- | SINE | Alu | Name=AluSg |
| ADediting_1341912 | chr7_5994544_- | SINE | Alu | Name=AluY |
| ADediting_1341913 | chr7_5994584_- | SINE | Alu | Name=AluY |
| ADediting_1341914 | chr7_5994609_- | SINE | Alu | Name=AluY |
| ADediting_1341915 | chr7_5994615_- | SINE | Alu | Name=AluY |
| ADediting_1341916 | chr7_5994654_- | SINE | Alu | Name=AluY |
| ADediting_1341917 | chr7_5994664_- | SINE | Alu | Name=AluY |
| ADediting_1341918 | chr7_5994719_- | SINE | Alu | Name=AluY |
| ADediting_1341919 | chr7_5994754_- | SINE | Alu | Name=AluY |
| ADediting_1341920 | chr7_5994773_- | SINE | Alu | Name=AluY |
| ADediting_1341921 | chr7_5995071_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341922 | chr7_5995095_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341923 | chr7_5995110_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341924 | chr7_5995111_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341925 | chr7_5995114_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341926 | chr7_5995134_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341927 | chr7_5995135_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341928 | chr7_5995140_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341929 | chr7_5995146_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341930 | chr7_5995149_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341931 | chr7_5995166_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341932 | chr7_5995170_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341933 | chr7_5995175_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341934 | chr7_5995176_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341935 | chr7_5995194_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341936 | chr7_5995198_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341937 | chr7_5995201_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341938 | chr7_5995219_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341939 | chr7_5995240_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341940 | chr7_5995241_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341941 | chr7_5995269_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341942 | chr7_5995304_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341943 | chr7_5995309_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341944 | chr7_5995310_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341945 | chr7_5995326_- | SINE | Alu | Name=AluSz6 |
| ADediting_1341946 | chr7_5996324_- | SINE | Alu | Name=AluSx1 |
| ADediting_1341947 | chr7_5996433_- | SINE | Alu | Name=AluSx1 |
| ADediting_1341948 | chr7_5998142_- | SINE | Alu | Name=AluSg |
| ADediting_1341949 | chr7_5998277_- | SINE | Alu | Name=AluSg |
| ADediting_1341950 | chr7_5998317_- | SINE | Alu | Name=AluSg |
| ADediting_1341951 | chr7_5998448_- | SINE | Alu | Name=AluSz |
| ADediting_1341952 | chr7_5998582_- | SINE | Alu | Name=AluSz |
| ADediting_1341953 | chr7_5998599_- | SINE | Alu | Name=AluSz |
| ADediting_1341954 | chr7_5998608_- | SINE | Alu | Name=AluSz |
| ADediting_1341955 | chr7_5998810_- | SINE | Alu | Name=AluSx3 |
| ADediting_1341956 | chr7_5998904_- | SINE | Alu | Name=AluSx3 |
| ADediting_1341957 | chr7_5998907_- | SINE | Alu | Name=AluSx3 |
| ADediting_1341958 | chr7_6001433_- | SINE | Alu | Name=AluSc |
| ADediting_1341959 | chr7_6001482_- | SINE | Alu | Name=AluSc |
| ADediting_1341960 | chr7_6001486_- | SINE | Alu | Name=AluSc |
| ADediting_1341961 | chr7_6001509_- | SINE | Alu | Name=AluSc |
| ADediting_1341962 | chr7_6001597_- | SINE | Alu | Name=AluSc |
| ADediting_1341963 | chr7_6001727_- | SINE | Alu | Name=AluSx |
| ADediting_1341964 | chr7_6001739_- | SINE | Alu | Name=AluSx |
| ADediting_1341965 | chr7_6001754_- | SINE | Alu | Name=AluSx |
| ADediting_1341966 | chr7_6001844_- | SINE | Alu | Name=AluSx |
| ADediting_1341967 | chr7_6001893_- | SINE | Alu | Name=AluSx |
| ADediting_1341968 | chr7_6001910_- | SINE | Alu | Name=AluSx |
| ADediting_1341969 | chr7_6001930_- | SINE | Alu | Name=AluSx |
| ADediting_1341970 | chr7_6004471_- | SINE | Alu | Name=AluSp |
| ADediting_1341971 | chr7_6005278_- | SINE | Alu | Name=AluSx1 |
| ADediting_1341972 | chr7_6006407_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341973 | chr7_6006434_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341974 | chr7_6006486_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341975 | chr7_6006531_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341976 | chr7_6006537_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341977 | chr7_6006541_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341978 | chr7_6006570_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341979 | chr7_6006606_- | SINE | Alu | Name=AluSq2 |
| ADediting_1341980 | chr7_6008024_- | SINE | Alu | Name=AluSx1 |
| ADediting_1587918 | chr7_5971882_- | SINE | Alu | Name=AluSq2 |
| ADediting_1587919 | chr7_5995153_- | SINE | Alu | Name=AluSz6 |
| ADediting_1666269 | chr7_5990201_- | SINE | Alu | Name=AluSz |
Top |
RNA A-to-I editing events in the alternative splicing sites for PMS2 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for PMS2 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for PMS2 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for PMS2 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1341799 | chr7_5971772_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-100-5p | chr7 | 5971769 | 5971775 | 7mer-m8 | 5971768 | 5971790 | 162 | -22.89 |
| ADediting_1341799 | chr7_5971772_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-99a-5p | chr7 | 5971769 | 5971775 | 7mer-m8 | 5971768 | 5971791 | 155 | -21.46 |
| ADediting_1341799 | chr7_5971772_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-99b-5p | chr7 | 5971769 | 5971775 | 7mer-m8 | 5971768 | 5971791 | 155 | -25.13 |
| ADediting_1341801 | chr7_5971826_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-28-5p | chr7 | 5971821 | 5971827 | 7mer-m8 | 5971820 | 5971840 | 151 | -22.03 |
| ADediting_1341801 | chr7_5971826_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-3139 | chr7 | 5971821 | 5971827 | 7mer-m8 | 5971820 | 5971842 | 165 | -26.52 |
| ADediting_1341801 | chr7_5971826_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-708-5p | chr7 | 5971821 | 5971827 | 7mer-m8 | 5971820 | 5971841 | 150 | -22.21 |
| ADediting_1341802 | chr7_5971839_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-3940-3p | chr7 | 5971835 | 5971841 | 7mer-m8 | 5971834 | 5971855 | 142 | -21.28 |
| ADediting_1341805 | chr7_5971935_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-6746-5p | chr7 | 5971935 | 5971941 | 7mer-m8 | 5971934 | 5971956 | 155 | -26.81 |
| ADediting_1341805 | chr7_5971935_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-6765-5p | chr7 | 5971930 | 5971936 | 7mer-m8 | 5971929 | 5971953 | 151 | -23.05 |
| ADediting_1341806 | chr7_5971947_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-3622a-3p | chr7 | 5971943 | 5971950 | 8mer-1a | 5971943 | 5971965 | 149 | -18.21 |
| ADediting_1341806 | chr7_5971947_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-3622b-3p | chr7 | 5971943 | 5971950 | 8mer-1a | 5971943 | 5971963 | 147 | -18.77 |
| ADediting_1341808 | chr7_5971954_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-1247-3p | chr7 | 5971952 | 5971958 | 7mer-m8 | 5971951 | 5971973 | 160 | -27.6 |
| ADediting_1341809 | chr7_5971978_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-4537 | chr7 | 5971973 | 5971980 | 8mer-1a | 5971973 | 5971995 | 155 | -20.83 |
| ADediting_1341811 | chr7_5972915_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-4284 | chr7 | 5972913 | 5972919 | 7mer-m8 | 5972912 | 5972929 | 151 | -17.62 |
| ADediting_1341811 | chr7_5972915_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-4638-5p | chr7 | 5972909 | 5972916 | 8mer-1a | 5972909 | 5972928 | 146 | -20.28 |
| ADediting_1341812 | chr7_5972940_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-4437 | chr7 | 5972937 | 5972943 | 7mer-m8 | 5972936 | 5972956 | 146 | -19.53 |
| ADediting_1341814 | chr7_5972949_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-4431 | chr7 | 5972946 | 5972952 | 7mer-m8 | 5972945 | 5972966 | 140 | -17.94 |
| ADediting_1341818 | chr7_5973020_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-630 | chr7 | 5973014 | 5973021 | 8mer-1a | 5973014 | 5973035 | 153 | -14.84 |
| ADediting_1341819 | chr7_5973021_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-325 | chr7 | 5973020 | 5973027 | 8mer-1a | 5973020 | 5973042 | 145 | -12.55 |
| ADediting_1341820 | chr7_5973022_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-222-5p | chr7 | 5973020 | 5973027 | 8mer-1a | 5973020 | 5973043 | 147 | -16.62 |
| ADediting_1341820 | chr7_5973022_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-30a-3p | chr7 | 5973018 | 5973025 | 8mer-1a | 5973018 | 5973038 | 145 | -11.99 |
| ADediting_1341820 | chr7_5973022_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-30d-3p | chr7 | 5973018 | 5973025 | 8mer-1a | 5973018 | 5973038 | 150 | -10.09 |
| ADediting_1341820 | chr7_5973022_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-30e-3p | chr7 | 5973018 | 5973025 | 8mer-1a | 5973018 | 5973038 | 145 | -9.7 |
| ADediting_1341821 | chr7_5973025_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-2467-3p | chr7 | 5973024 | 5973030 | 7mer-m8 | 5973023 | 5973044 | 163 | -27.26 |
| ADediting_1341821 | chr7_5973025_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-374b-3p | chr7 | 5973020 | 5973027 | 8mer-1a | 5973020 | 5973041 | 141 | -8.96 |
| ADediting_1341822 | chr7_5973036_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-3158-3p | chr7 | 5973032 | 5973038 | 7mer-m8 | 5973031 | 5973051 | 158 | -21.39 |
| ADediting_1341822 | chr7_5973036_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-6815-3p | chr7 | 5973034 | 5973040 | 7mer-m8 | 5973033 | 5973054 | 147 | -16.85 |
| ADediting_1341823 | chr7_5973037_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-1182 | chr7 | 5973032 | 5973038 | 7mer-m8 | 5973031 | 5973053 | 141 | -16.04 |
| ADediting_1341823 | chr7_5973037_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-6895-3p | chr7 | 5973035 | 5973041 | 7mer-m8 | 5973034 | 5973055 | 150 | -15.95 |
| ADediting_1341826 | chr7_5973046_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-6131 | chr7 | 5973044 | 5973051 | 8mer-1a | 5973044 | 5973062 | 155 | -22.81 |
| ADediting_1341827 | chr7_5973050_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-4435 | chr7 | 5973046 | 5973053 | 8mer-1a | 5973046 | 5973066 | 146 | -18.85 |
| ADediting_1341827 | chr7_5973050_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-4755-3p | chr7 | 5973049 | 5973055 | 7mer-m8 | 5973048 | 5973069 | 145 | -16.93 |
| ADediting_1341829 | chr7_5973061_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-4281 | chr7 | 5973056 | 5973063 | 8mer-1a | 5973056 | 5973073 | 142 | -19.49 |
| ADediting_1341829 | chr7_5973061_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-6716-3p | chr7 | 5973061 | 5973067 | 7mer-m8 | 5973060 | 5973081 | 145 | -16.24 |
| ADediting_1341833 | chr7_5973075_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-4726-3p | chr7 | 5973073 | 5973080 | 8mer-1a | 5973073 | 5973095 | 158 | -29.47 |
| ADediting_1587918 | chr7_5971882_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-548ae-3p | chr7 | 5971877 | 5971883 | 7mer-m8 | 5971876 | 5971897 | 150 | -10.87 |
| ADediting_1587918 | chr7_5971882_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-548ah-3p | chr7 | 5971877 | 5971883 | 7mer-m8 | 5971876 | 5971900 | 154 | -16.71 |
| ADediting_1587918 | chr7_5971882_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-548aj-3p | chr7 | 5971877 | 5971883 | 7mer-m8 | 5971876 | 5971897 | 150 | -8.76 |
| ADediting_1587918 | chr7_5971882_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-548am-3p | chr7 | 5971877 | 5971883 | 7mer-m8 | 5971876 | 5971900 | 154 | -16.44 |
| ADediting_1587918 | chr7_5971882_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-548aq-3p | chr7 | 5971877 | 5971883 | 7mer-m8 | 5971876 | 5971898 | 151 | -11.25 |
| ADediting_1587918 | chr7_5971882_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-548j-3p | chr7 | 5971877 | 5971883 | 7mer-m8 | 5971876 | 5971898 | 146 | -10.87 |
| ADediting_1587918 | chr7_5971882_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-548x-3p | chr7 | 5971877 | 5971883 | 7mer-m8 | 5971876 | 5971896 | 150 | -8.76 |
| ADediting_1587918 | chr7_5971882_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-7844-5p | chr7 | 5971879 | 5971885 | 7mer-m8 | 5971878 | 5971898 | 161 | -20.59 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1341800 | chr7_5971814_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-3622a-3p | chr7 | 5971809 | 5971816 | 8mer-1a | 5971809 | 5971830 | 144 | -13.89 |
| ADediting_1341800 | chr7_5971814_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-3622b-3p | chr7 | 5971809 | 5971816 | 8mer-1a | 5971809 | 5971829 | 153 | -19.33 |
| ADediting_1341800 | chr7_5971814_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-7162-3p | chr7 | 5971813 | 5971819 | 7mer-m8 | 5971812 | 5971832 | 142 | -17.47 |
| ADediting_1341804 | chr7_5971930_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-4478 | chr7 | 5971926 | 5971932 | 7mer-m8 | 5971925 | 5971941 | 155 | -27.56 |
| ADediting_1341804 | chr7_5971930_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-485-5p | chr7 | 5971925 | 5971931 | 7mer-m8 | 5971924 | 5971945 | 153 | -19.61 |
| ADediting_1341804 | chr7_5971930_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-6884-5p | chr7 | 5971925 | 5971931 | 7mer-m8 | 5971924 | 5971944 | 155 | -21.16 |
| ADediting_1341804 | chr7_5971930_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-7160-5p | chr7 | 5971928 | 5971934 | 7mer-m8 | 5971927 | 5971947 | 150 | -18.56 |
| ADediting_1341805 | chr7_5971935_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-1233-5p | chr7 | 5971934 | 5971940 | 7mer-m8 | 5971933 | 5971954 | 141 | -16.98 |
| ADediting_1341805 | chr7_5971935_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-30c-1-3p | chr7 | 5971935 | 5971941 | 7mer-m8 | 5971934 | 5971953 | 146 | -14.98 |
| ADediting_1341805 | chr7_5971935_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-30c-2-3p | chr7 | 5971935 | 5971941 | 7mer-m8 | 5971934 | 5971955 | 145 | -16.5 |
| ADediting_1341805 | chr7_5971935_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-6778-5p | chr7 | 5971934 | 5971940 | 7mer-m8 | 5971933 | 5971955 | 147 | -20.68 |
| ADediting_1341805 | chr7_5971935_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-6788-5p | chr7 | 5971935 | 5971941 | 7mer-m8 | 5971934 | 5971953 | 149 | -16.14 |
| ADediting_1341806 | chr7_5971947_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-3614-5p | chr7 | 5971943 | 5971949 | 7mer-1a | 5971943 | 5971966 | 155 | -25.83 |
| ADediting_1341807 | chr7_5971948_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-3614-5p | chr7 | 5971943 | 5971949 | 7mer-1a | 5971943 | 5971966 | 155 | -25.83 |
| ADediting_1341808 | chr7_5971954_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-3689a-3p | chr7 | 5971954 | 5971960 | 7mer-m8 | 5971953 | 5971976 | 143 | -22.1 |
| ADediting_1341808 | chr7_5971954_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-3689b-3p | chr7 | 5971954 | 5971960 | 7mer-m8 | 5971953 | 5971973 | 150 | -24.19 |
| ADediting_1341808 | chr7_5971954_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-3689c | chr7 | 5971954 | 5971960 | 7mer-m8 | 5971953 | 5971973 | 150 | -24.19 |
| ADediting_1341808 | chr7_5971954_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-490-3p | chr7 | 5971950 | 5971956 | 7mer-m8 | 5971949 | 5971971 | 146 | -21.32 |
| ADediting_1341808 | chr7_5971954_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-6779-5p | chr7 | 5971954 | 5971960 | 7mer-m8 | 5971953 | 5971971 | 148 | -26.05 |
| ADediting_1341808 | chr7_5971954_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-6780a-5p | chr7 | 5971954 | 5971960 | 7mer-m8 | 5971953 | 5971977 | 155 | -28.51 |
| ADediting_1341809 | chr7_5971978_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-3160-3p | chr7 | 5971973 | 5971980 | 8mer-1a | 5971973 | 5971994 | 153 | -16.09 |
| ADediting_1341812 | chr7_5972940_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-498-5p | chr7 | 5972940 | 5972946 | 7mer-m8 | 5972939 | 5972961 | 142 | -9.71 |
| ADediting_1341813 | chr7_5972941_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-498-5p | chr7 | 5972940 | 5972946 | 7mer-m8 | 5972939 | 5972961 | 142 | -9.71 |
| ADediting_1341815 | chr7_5972955_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-1976 | chr7 | 5972950 | 5972957 | 8mer-1a | 5972950 | 5972970 | 153 | -24.57 |
| ADediting_1341815 | chr7_5972955_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-6747-3p | chr7 | 5972952 | 5972959 | 8mer-1a | 5972952 | 5972974 | 149 | -22.95 |
| ADediting_1341816 | chr7_5972968_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-1229-5p | chr7 | 5972968 | 5972974 | 7mer-m8 | 5972967 | 5972993 | 149 | -25.41 |
| ADediting_1341816 | chr7_5972968_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-1343-3p | chr7 | 5972965 | 5972971 | 7mer-m8 | 5972964 | 5972985 | 141 | -20.73 |
| ADediting_1341816 | chr7_5972968_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-6742-3p | chr7 | 5972965 | 5972972 | 8mer-1a | 5972965 | 5972984 | 143 | -14.18 |
| ADediting_1341816 | chr7_5972968_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-6783-3p | chr7 | 5972965 | 5972971 | 7mer-m8 | 5972964 | 5972985 | 140 | -16.28 |
| ADediting_1341821 | chr7_5973025_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-6866-5p | chr7 | 5973025 | 5973031 | 7mer-m8 | 5973024 | 5973046 | 147 | -14.07 |
| ADediting_1341822 | chr7_5973036_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-6823-5p | chr7 | 5973031 | 5973037 | 7mer-m8 | 5973030 | 5973050 | 151 | -16.46 |
| ADediting_1341825 | chr7_5973044_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-4716-5p | chr7 | 5973040 | 5973047 | 8mer-1a | 5973040 | 5973061 | 140 | -10.67 |
| ADediting_1341825 | chr7_5973044_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-4781-3p | chr7 | 5973043 | 5973049 | 7mer-m8 | 5973042 | 5973065 | 142 | -13.55 |
| ADediting_1341826 | chr7_5973046_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-4716-5p | chr7 | 5973040 | 5973047 | 8mer-1a | 5973040 | 5973061 | 140 | -10.67 |
| ADediting_1341826 | chr7_5973046_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-4781-3p | chr7 | 5973043 | 5973049 | 7mer-m8 | 5973042 | 5973065 | 142 | -13.55 |
| ADediting_1341828 | chr7_5973056_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-3663-5p | chr7 | 5973055 | 5973061 | 7mer-m8 | 5973054 | 5973073 | 148 | -19.95 |
| ADediting_1341828 | chr7_5973056_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-6131 | chr7 | 5973054 | 5973060 | 7mer-m8 | 5973053 | 5973071 | 140 | -18.33 |
| ADediting_1341828 | chr7_5973056_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-6843-3p | chr7 | 5973056 | 5973062 | 7mer-m8 | 5973055 | 5973074 | 152 | -16.98 |
| ADediting_1341828 | chr7_5973056_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-6848-3p | chr7 | 5973056 | 5973062 | 7mer-m8 | 5973055 | 5973073 | 140 | -12.07 |
| ADediting_1341829 | chr7_5973061_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-6843-3p | chr7 | 5973056 | 5973062 | 7mer-m8 | 5973055 | 5973074 | 152 | -16.98 |
| ADediting_1341829 | chr7_5973061_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-6848-3p | chr7 | 5973056 | 5973062 | 7mer-m8 | 5973055 | 5973073 | 140 | -12.07 |
| ADediting_1341830 | chr7_5973067_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-4762-3p | chr7 | 5973067 | 5973073 | 7mer-m8 | 5973066 | 5973091 | 146 | -22.77 |
| ADediting_1341831 | chr7_5973068_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-3192-3p | chr7 | 5973067 | 5973074 | 8mer-1a | 5973067 | 5973087 | 142 | -11.66 |
| ADediting_1341831 | chr7_5973068_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-4762-3p | chr7 | 5973067 | 5973073 | 7mer-m8 | 5973066 | 5973091 | 146 | -22.77 |
| ADediting_1341832 | chr7_5973070_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-3192-3p | chr7 | 5973067 | 5973074 | 8mer-1a | 5973067 | 5973087 | 142 | -11.66 |
| ADediting_1341832 | chr7_5973070_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-4762-3p | chr7 | 5973067 | 5973073 | 7mer-m8 | 5973066 | 5973091 | 146 | -22.77 |
| ADediting_1341833 | chr7_5973075_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-4695-3p | chr7 | 5973070 | 5973077 | 8mer-1a | 5973070 | 5973098 | 148 | -28.09 |
| ADediting_1341834 | chr7_5973080_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-125a-3p | chr7 | 5973075 | 5973082 | 8mer-1a | 5973075 | 5973094 | 143 | -17.92 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337757 | chr7_5495852_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-589-3p | chr7 | 5972788 | 5972794 | 7mer-m8 | 5972787 | 5972810 | 156 | -18.37 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-151a-3p | chr7 | 5971691 | 5971697 | 7mer-m8 | 5971690 | 5971711 | 146 | -20.69 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1596844 | chr1_162342605_+ | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-556-3p | chr7 | 5970950 | 5970957 | 8mer-1a | 5970950 | 5970972 | 144 | -10.54 |
| ADediting_527135 | chr16_24203190_+ | ENSG00000122512.16 | ENST00000265849.12 | PMS2-201 | hsa-miR-1273h-3p | chr7 | 5972192 | 5972198 | 7mer-m8 | 5972191 | 5972213 | 155 | -26.6 |
| Differentially expressed gene-miRNA network |
| Differentially expressed lncRNA-miRNA network |
 |
Top |
The effects of the RNA editing to the stability of the RNA structures for PMS2 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000265849.12 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_1341799 | ENST00000265849.12 | chr7_5971772_- | 4246 | -1821.30 | -1822.00 | -1862.00 |
| ADediting_1341800 | ENST00000265849.12 | chr7_5971814_- | 4204 | -1821.30 | -1822.00 | -1862.00 |
| ADediting_1341801 | ENST00000265849.12 | chr7_5971826_- | 4192 | -1822.00 | -1822.00 | -1862.00 |
| ADediting_1341802 | ENST00000265849.12 | chr7_5971839_- | 4179 | -1821.30 | -1822.00 | -1862.00 |
| ADediting_1341803 | ENST00000265849.12 | chr7_5971868_- | 4150 | -1821.70 | -1822.00 | -1862.00 |
| ADediting_1587918 | ENST00000265849.12 | chr7_5971882_- | 4136 | -1822.00 | -1822.00 | -1862.00 |
| ADediting_1341804 | ENST00000265849.12 | chr7_5971930_- | 4088 | -1821.30 | -1822.00 | -1862.00 |
| ADediting_1341805 | ENST00000265849.12 | chr7_5971935_- | 4083 | -1825.90 | -1822.00 | -1862.00 |
| ADediting_1341806 | ENST00000265849.12 | chr7_5971947_- | 4071 | -1821.70 | -1822.00 | -1862.00 |
| ADediting_1341807 | ENST00000265849.12 | chr7_5971948_- | 4070 | -1821.70 | -1822.00 | -1862.00 |
| ADediting_1341808 | ENST00000265849.12 | chr7_5971954_- | 4064 | -1828.20 | -1822.00 | -1862.00 |
| ADediting_1341809 | ENST00000265849.12 | chr7_5971978_- | 4040 | -1828.20 | -1822.00 | -1862.00 |
| ADediting_1341810 | ENST00000265849.12 | chr7_5971989_- | 4029 | -1828.20 | -1822.00 | -1862.00 |
| ADediting_1341811 | ENST00000265849.12 | chr7_5972915_- | 3103 | -1828.70 | -1822.00 | -1862.00 |
| ADediting_1341812 | ENST00000265849.12 | chr7_5972940_- | 3078 | -1822.00 | -1822.00 | -1862.00 |
| ADediting_1341813 | ENST00000265849.12 | chr7_5972941_- | 3077 | -1821.50 | -1822.00 | -1862.00 |
| ADediting_1341814 | ENST00000265849.12 | chr7_5972949_- | 3069 | -1822.00 | -1822.00 | -1862.00 |
| ADediting_1341815 | ENST00000265849.12 | chr7_5972955_- | 3063 | -1826.70 | -1822.00 | -1862.00 |
| ADediting_1341816 | ENST00000265849.12 | chr7_5972968_- | 3050 | -1828.20 | -1822.00 | -1862.00 |
| ADediting_1341817 | ENST00000265849.12 | chr7_5973019_- | 2999 | -1822.10 | -1822.00 | -1862.00 |
| ADediting_1341818 | ENST00000265849.12 | chr7_5973020_- | 2998 | -1822.10 | -1822.00 | -1862.00 |
| ADediting_1341819 | ENST00000265849.12 | chr7_5973021_- | 2997 | -1822.10 | -1822.00 | -1862.00 |
| ADediting_1341820 | ENST00000265849.12 | chr7_5973022_- | 2996 | -1822.10 | -1822.00 | -1862.00 |
| ADediting_1341821 | ENST00000265849.12 | chr7_5973025_- | 2993 | -1822.00 | -1822.00 | -1862.00 |
| ADediting_1341822 | ENST00000265849.12 | chr7_5973036_- | 2982 | -1822.00 | -1822.00 | -1862.00 |
| ADediting_1341823 | ENST00000265849.12 | chr7_5973037_- | 2981 | -1822.10 | -1822.00 | -1862.00 |
| ADediting_1341824 | ENST00000265849.12 | chr7_5973040_- | 2978 | -1822.40 | -1822.00 | -1862.00 |
| ADediting_1341825 | ENST00000265849.12 | chr7_5973044_- | 2974 | -1821.60 | -1822.00 | -1862.00 |
| ADediting_1341826 | ENST00000265849.12 | chr7_5973046_- | 2972 | -1822.00 | -1822.00 | -1862.00 |
| ADediting_1341827 | ENST00000265849.12 | chr7_5973050_- | 2968 | -1825.70 | -1822.00 | -1862.00 |
| ADediting_1341828 | ENST00000265849.12 | chr7_5973056_- | 2962 | -1821.30 | -1822.00 | -1862.00 |
| ADediting_1341829 | ENST00000265849.12 | chr7_5973061_- | 2957 | -1821.10 | -1822.00 | -1862.00 |
| ADediting_1341830 | ENST00000265849.12 | chr7_5973067_- | 2951 | -1822.00 | -1822.00 | -1862.00 |
| ADediting_1341831 | ENST00000265849.12 | chr7_5973068_- | 2950 | -1828.90 | -1822.00 | -1862.00 |
| ADediting_1341832 | ENST00000265849.12 | chr7_5973070_- | 2948 | -1821.30 | -1822.00 | -1862.00 |
| ADediting_1341833 | ENST00000265849.12 | chr7_5973075_- | 2943 | -1821.10 | -1822.00 | -1862.00 |
| ADediting_1341834 | ENST00000265849.12 | chr7_5973080_- | 2938 | -1821.60 | -1822.00 | -1862.00 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for PMS2 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_1341803 | chr7_5971868_- | 0.000222157129276134 | 0.208251085973449 | 0.130392182071527 | 0.0860956948526969 | 1.67251132144184e-19 | 0.482750757863558 |
| DLPFC | ADediting_1341805 | chr7_5971935_- | 5.54827550441771e-09 | 0.323474812034281 | 7.40207971273941e-07 | 0.276776194301344 | 1.92628330486256e-10 | 0.351446133901937 |
| DLPFC | ADediting_1341806 | chr7_5971947_- | 0.00038255067878878 | 0.200488728620029 | 0.00139035293400091 | 0.180789314998515 | 4.28842135154521e-09 | 0.325721092068524 |
| DLPFC | ADediting_1341807 | chr7_5971948_- | 4.00247931737672e-05 | 0.231050273923694 | 0.00220596847360328 | 0.173236788096899 | 2.01274410139193e-13 | 0.401285491557337 |
| DLPFC | ADediting_1341808 | chr7_5971954_- | 7.97139544447629e-08 | 0.299071359619648 | 2.73036537376973e-06 | 0.26274777964664 | 4.62446480060421e-09 | 0.325065054277612 |
| DLPFC | ADediting_1341809 | chr7_5971978_- | 2.29166034118602e-06 | 0.264676996577586 | 4.23283382037538e-05 | 0.230341640104239 | 4.81056956307259e-08 | 0.303869937735622 |
| DLPFC | ADediting_1341810 | chr7_5971989_- | 0.00104927909384369 | 0.185254128974969 | 0.013862973400007 | 0.139642409497756 | 2.99267145622115e-09 | 0.328828166637481 |
| TCX | ADediting_1341811 | chr7_5972915_- | 0.000516775752151898 | 0.280126054362489 | 4.98748681814263e-05 | 0.324876869191738 | 0.222503078744368 | -0.100191664394212 |
| TCX | ADediting_1341812 | chr7_5972940_- | 0.00466635248493663 | 0.229825863054943 | 9.25791619034669e-06 | 0.353234417251003 | 0.0276649991130541 | -0.179828927216179 |
| TCX | ADediting_1341814 | chr7_5972949_- | 0.0829375018449061 | 0.142041087737574 | 1.76929969955139e-08 | 0.439950867257582 | 0.36181049446496 | -0.0749803737718065 |
| TCX | ADediting_1341815 | chr7_5972955_- | 0.000411189694713575 | 0.284835582813484 | 4.37668756204815e-08 | 0.428824828779947 | 0.373783301474551 | -0.0731344366625509 |
| TCX | ADediting_1341816 | chr7_5972968_- | 0.0547280641931918 | 0.157189801088945 | 5.35633459540251e-06 | 0.361888081111645 | 0.292131962077743 | -0.0865769707939499 |
| CER | ADediting_1341822 | chr7_5973036_- | 0.0787921757344641 | 0.143974381887552 | 4.43624685061248e-05 | 0.326941541170791 | 0.362224882124729 | -0.0749158593106284 |
| DLPFC | ADediting_1341843 | chr7_5978938_- | 0.054835035791619 | 0.109173799195554 | 0.99070676539928 | -0.00066422277701225 | 4.81936967366731e-09 | 0.32470540106626 |
| DLPFC | ADediting_1341845 | chr7_5978977_- | 0.0950254644943019 | 0.0949884053575144 | 0.879946184047181 | -0.00861298525865278 | 9.94306883626075e-13 | 0.390420057846423 |
| DLPFC | ADediting_1341876 | chr7_5992374_- | 0.352077848960839 | 0.0530296550443725 | 0.52568242506548 | -0.0361778073145907 | 3.76508517443124e-09 | 0.326849189275198 |
| DLPFC | ADediting_1341918 | chr7_5994719_- | 0.000155463888183918 | 0.213199516686875 | 0.0985943324175208 | 0.0939825672210318 | 1.08176606491733e-13 | 0.405404071064712 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 2.49347087385578e-33 | 0.61265091820163 | 2.3645823038492e-19 | 0.480977870369154 | 8.55099126925244e-17 | 0.449125292216375 |
| AC | 2.82815076500284e-93 | 0.903579928180815 | 4.6423901290328e-63 | 0.823752276981073 | 1.95923879927976e-08 | 0.34587098060402 |
| PCC | 2.88186348456696e-78 | 0.918880811249623 | 2.39930007425235e-67 | 0.892721225365212 | 0.0508580328188416 | 0.141507750209011 |
| CER | 1.08508564159884e-18 | 0.640499768443814 | 4.57042910335236e-06 | 0.364350947130867 | 0.650218930662161 | -0.0373240232058968 |
| TCX | 7.54564187422159e-39 | 0.827021398484676 | 3.7678665933806e-24 | 0.708321472294026 | 0.629560026397223 | -0.03969997935552 |
| FP | 2.28868816035004e-27 | 0.698455572971978 | 3.27889602489542e-31 | 0.732530374108296 | 0.437375713485314 | 0.0585737214658544 |
| IFG | 1.3531614695207e-05 | 0.753852841559169 | 0.000778353392074214 | 0.627892605831516 | 0.865799036424058 | -0.0356119531409622 |
| PG | 1.02169668756969e-58 | 0.871082719116646 | 2.14510763296752e-40 | 0.786676831979032 | 0.20637076714096 | -0.0930784280742656 |
| STG | 1.33083679860438e-27 | 0.875317105443371 | 6.31982605519229e-19 | 0.787600095132315 | 0.729671835236286 | 0.0382634379813172 |
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Relation with AD stages for PMS2 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
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RelatedDrugs for PMS2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PMS2 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| PMS2 | C1838333 | COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 4 | 17 | CLINGEN;CTD_human;UNIPROT |
| PMS2 | C0265325 | Turcot syndrome (disorder) | 6 | CTD_human;ORPHANET;UNIPROT |
| PMS2 | C0346153 | Breast Cancer, Familial | 4 | CLINGEN;GENOMICS_ENGLAND |
| PMS2 | C0009405 | Hereditary Nonpolyposis Colorectal Neoplasms | 3 | CTD_human |
| PMS2 | C1333990 | Hereditary Nonpolyposis Colorectal Cancer | 3 | CTD_human;ORPHANET |
| PMS2 | C0376545 | Hematologic Neoplasms | 2 | GENOMICS_ENGLAND |
| PMS2 | C0017185 | Gastrointestinal Neoplasms | 1 | GENOMICS_ENGLAND |
| PMS2 | C0027627 | Neoplasm Metastasis | 1 | CTD_human |
| PMS2 | C0027831 | Neurofibromatosis 1 | 1 | GENOMICS_ENGLAND |
| PMS2 | C0035412 | Rhabdomyosarcoma | 1 | CTD_human |
| PMS2 | C0038874 | Supratentorial Neoplasms | 1 | CTD_human |
| PMS2 | C0206663 | Neuroectodermal Tumor, Primitive | 1 | CTD_human |
| PMS2 | C0221263 | Cafe-au-Lait Spots | 1 | CTD_human |
| PMS2 | C0334584 | Spongioblastoma | 1 | CTD_human |
| PMS2 | C0334596 | Medulloepithelioma | 1 | CTD_human |
| PMS2 | C0700367 | Ependymoblastoma | 1 | CTD_human |
| PMS2 | C0751588 | Benign Supratentorial Neoplasms | 1 | CTD_human |
| PMS2 | C0751589 | Cancer, Supratentorial | 1 | CTD_human |
| PMS2 | C0751590 | Primary Supratentorial Neoplasms | 1 | CTD_human |
| PMS2 | C0751675 | Cerebral Primitive Neuroectodermal Tumor | 1 | CTD_human |
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