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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for ATP6V1E1 |
 Gene summary |
| Gene information | Gene symbol | ATP6V1E1 | Gene ID | 529 |
| Gene name | ATPase H+ transporting V1 subunit E1 | |
| Synonyms | ARCL2C|ATP6E|ATP6E2|ATP6V1E|P31|Vma4 | |
| Cytomap | 22q11.21 | |
| Type of gene | protein-coding | |
| Description | V-type proton ATPase subunit E 1ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1H(+)-transporting two-sector ATPase, 31kDa subunitH+-transporting ATP synthase chain E, vacuolarV-ATPase 31 kDa subunitV-ATPase subunit E 1V-ATPase, subunit Evac | |
| Modification date | 20200313 | |
| UniProtAcc | P36543, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
RNA A-to-I events for ATP6V1E1 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_965226(17592877, -), ADediting_965227(17592909, -), ADediting_965228(17592916, -), ADediting_965229(17592926, -), ADediting_965230(17592932, -), ADediting_965231(17592935, -), ADediting_965232(17592948, -), ADediting_965233(17592952, -), ADediting_965234(17592983, -), ADediting_965235(17592993, -), ADediting_965236(17594040, -), ADediting_965237(17594080, -), ADediting_965238(17594090, -), ADediting_965239(17594182, -), ADediting_965240(17595108, -), ADediting_965241(17595113, -), ADediting_965242(17595115, -), ADediting_965243(17595116, -), ADediting_965244(17595133, -), ADediting_965245(17595144, -), ADediting_965246(17595153, -), ADediting_965247(17595159, -), ADediting_965248(17595180, -), ADediting_965249(17595185, -), ADediting_965250(17595186, -), ADediting_965251(17595196, -), ADediting_965252(17595212, -), ADediting_965253(17595216, -), ADediting_965254(17595221, -), ADediting_965255(17595250, -), ADediting_965256(17595251, -), ADediting_965257(17595263, -), ADediting_965258(17595265, -), ADediting_965259(17595266, -), ADediting_965260(17595313, -), ADediting_965261(17595314, -), ADediting_965262(17595319, -), ADediting_965263(17595320, -), ADediting_965264(17595573, -), ADediting_965265(17595649, -), ADediting_965266(17595699, -), ADediting_965267(17595794, -), ADediting_965268(17595874, -), ADediting_965269(17595887, -), ADediting_965270(17595925, -), ADediting_965271(17595926, -), ADediting_965272(17595937, -), ADediting_965273(17595941, -), ADediting_965274(17595949, -), ADediting_965275(17595963, -), ADediting_965276(17596010, -), ADediting_965277(17596020, -), ADediting_965278(17596056, -), ADediting_965279(17596063, -), ADediting_965280(17596088, -), ADediting_965281(17596116, -), ADediting_965282(17596986, -), ADediting_965283(17596998, -), ADediting_965284(17597048, -), ADediting_965285(17597052, -), ADediting_965286(17597120, -), ADediting_965287(17597130, -), ADediting_965288(17597159, -), ADediting_965289(17597160, -), ADediting_965290(17597166, -), ADediting_965291(17597198, -), ADediting_965292(17597243, -), ADediting_965293(17597383, -), ADediting_965294(17597657, -), ADediting_965295(17597658, -), ADediting_965296(17597723, -), ADediting_965297(17597742, -), ADediting_965298(17597769, -), ADediting_965299(17597795, -), ADediting_965300(17597804, -), ADediting_965301(17597810, -), ADediting_965302(17597813, -), ADediting_965303(17597905, -), ADediting_965304(17597906, -), ADediting_965305(17597911, -), ADediting_965306(17597912, -), ADediting_965307(17597914, -), ADediting_965308(17597923, -), ADediting_965309(17597950, -), ADediting_965310(17603169, -), ADediting_965311(17603196, -), ADediting_965312(17603621, -), ADediting_965313(17603647, -), ADediting_965314(17604553, -), ADediting_965315(17604554, -), ADediting_965316(17604625, -), ADediting_965317(17604657, -), ADediting_965318(17604687, -), ADediting_965319(17604701, -), ADediting_965320(17604732, -), ADediting_965321(17604789, -), ADediting_965322(17604790, -), ADediting_965323(17605023, -), ADediting_965324(17605050, -), ADediting_965325(17605054, -), ADediting_965326(17605069, -), ADediting_965327(17605072, -), ADediting_965328(17605093, -), ADediting_965329(17605122, -), ADediting_965330(17605123, -), ADediting_965331(17605153, -), ADediting_965332(17605368, -), ADediting_965333(17605491, -), ADediting_965334(17605728, -), ADediting_965335(17605797, -), ADediting_965336(17605859, -), ADediting_965337(17605868, -), ADediting_965338(17605873, -), ADediting_965339(17605898, -), ADediting_965340(17605933, -), ADediting_965341(17605935, -), ADediting_965342(17607243, -), ADediting_965343(17607402, -), ADediting_965344(17608687, -), ADediting_965345(17608893, -), ADediting_965346(17608897, -), ADediting_965347(17608919, -), ADediting_965348(17608937, -), ADediting_965349(17608938, -), ADediting_965350(17608974, -), ADediting_965351(17609074, -), ADediting_965352(17609196, -), ADediting_965353(17609272, -), ADediting_965354(17609299, -), ADediting_965355(17609325, -), ADediting_965356(17610031, -), ADediting_965357(17610036, -), ADediting_965358(17614188, -), ADediting_965359(17614319, -), ADediting_965360(17617895, -), ADediting_965361(17617902, -), ADediting_965362(17618029, -), ADediting_965363(17618056, -), ADediting_965364(17618082, -), ADediting_965365(17618606, -), ADediting_965366(17619718, -), ADediting_965367(17620414, -), ADediting_965368(17620419, -), ADediting_965369(17625328, -), ADediting_965370(17625396, -), ADediting_965371(17625397, -), ADediting_965372(17626117, -), ADediting_965373(17626245, -), ADediting_965374(17626264, -), ADediting_965375(17626466, -), ADediting_965376(17627402, -), ADediting_965377(17627634, -), ADediting_965378(17627656, -), ADediting_965379(17627697, -), ADediting_965380(17627699, -), ADediting_965381(17627721, -), ADediting_965382(17627739, -), ADediting_965383(17627756, -), ADediting_965384(17627780, -), ADediting_965385(17627805, -), ADediting_965386(17628103, -), ADediting_965387(17628104, -), ADediting_965388(17628130, -), ADediting_965389(17628138, -), ADediting_965390(17628168, -), ADediting_965391(17628239, -), ADediting_1569462(17595260, -), ADediting_1569463(17595901, -), ADediting_1569464(17597763, -), ADediting_1569465(17597800, -), ADediting_1642046(17608517, -), ADediting_1642047(17608541, -), ADediting_1642048(17626610, -), ADediting_1642049(17626656, -), |
Top |
RNA editing positional annotations for ATP6V1E1 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_965226 | chr22_17592877_- | intronic |
| ADediting_965227 | chr22_17592909_- | intronic |
| ADediting_965228 | chr22_17592916_- | intronic |
| ADediting_965229 | chr22_17592926_- | intronic |
| ADediting_965230 | chr22_17592932_- | intronic |
| ADediting_965231 | chr22_17592935_- | intronic |
| ADediting_965232 | chr22_17592948_- | intronic |
| ADediting_965233 | chr22_17592952_- | intronic |
| ADediting_965234 | chr22_17592983_- | intronic |
| ADediting_965235 | chr22_17592993_- | intronic |
| ADediting_965236 | chr22_17594040_- | intronic |
| ADediting_965237 | chr22_17594080_- | intronic |
| ADediting_965238 | chr22_17594090_- | intronic |
| ADediting_965239 | chr22_17594182_- | intronic |
| ADediting_965240 | chr22_17595108_- | intronic |
| ADediting_965241 | chr22_17595113_- | intronic |
| ADediting_965242 | chr22_17595115_- | intronic |
| ADediting_965243 | chr22_17595116_- | intronic |
| ADediting_965244 | chr22_17595133_- | intronic |
| ADediting_965245 | chr22_17595144_- | intronic |
| ADediting_965246 | chr22_17595153_- | intronic |
| ADediting_965247 | chr22_17595159_- | intronic |
| ADediting_965248 | chr22_17595180_- | intronic |
| ADediting_965249 | chr22_17595185_- | intronic |
| ADediting_965250 | chr22_17595186_- | intronic |
| ADediting_965251 | chr22_17595196_- | intronic |
| ADediting_965252 | chr22_17595212_- | intronic |
| ADediting_965253 | chr22_17595216_- | intronic |
| ADediting_965254 | chr22_17595221_- | intronic |
| ADediting_965255 | chr22_17595250_- | intronic |
| ADediting_965256 | chr22_17595251_- | intronic |
| ADediting_965257 | chr22_17595263_- | intronic |
| ADediting_965258 | chr22_17595265_- | intronic |
| ADediting_965259 | chr22_17595266_- | intronic |
| ADediting_965260 | chr22_17595313_- | intronic |
| ADediting_965261 | chr22_17595314_- | intronic |
| ADediting_965262 | chr22_17595319_- | intronic |
| ADediting_965263 | chr22_17595320_- | intronic |
| ADediting_965264 | chr22_17595573_- | intronic |
| ADediting_965265 | chr22_17595649_- | intronic |
| ADediting_965266 | chr22_17595699_- | intronic |
| ADediting_965267 | chr22_17595794_- | intronic |
| ADediting_965268 | chr22_17595874_- | intronic |
| ADediting_965269 | chr22_17595887_- | intronic |
| ADediting_965270 | chr22_17595925_- | intronic |
| ADediting_965271 | chr22_17595926_- | intronic |
| ADediting_965272 | chr22_17595937_- | intronic |
| ADediting_965273 | chr22_17595941_- | intronic |
| ADediting_965274 | chr22_17595949_- | intronic |
| ADediting_965275 | chr22_17595963_- | intronic |
| ADediting_965276 | chr22_17596010_- | intronic |
| ADediting_965277 | chr22_17596020_- | intronic |
| ADediting_965278 | chr22_17596056_- | intronic |
| ADediting_965279 | chr22_17596063_- | intronic |
| ADediting_965280 | chr22_17596088_- | intronic |
| ADediting_965281 | chr22_17596116_- | intronic |
| ADediting_965282 | chr22_17596986_- | intronic |
| ADediting_965283 | chr22_17596998_- | intronic |
| ADediting_965284 | chr22_17597048_- | intronic |
| ADediting_965285 | chr22_17597052_- | intronic |
| ADediting_965286 | chr22_17597120_- | intronic |
| ADediting_965287 | chr22_17597130_- | intronic |
| ADediting_965288 | chr22_17597159_- | intronic |
| ADediting_965289 | chr22_17597160_- | intronic |
| ADediting_965290 | chr22_17597166_- | intronic |
| ADediting_965291 | chr22_17597198_- | intronic |
| ADediting_965292 | chr22_17597243_- | intronic |
| ADediting_965293 | chr22_17597383_- | intronic |
| ADediting_965294 | chr22_17597657_- | intronic |
| ADediting_965295 | chr22_17597658_- | intronic |
| ADediting_965296 | chr22_17597723_- | intronic |
| ADediting_965297 | chr22_17597742_- | intronic |
| ADediting_965298 | chr22_17597769_- | intronic |
| ADediting_965299 | chr22_17597795_- | intronic |
| ADediting_965300 | chr22_17597804_- | intronic |
| ADediting_965301 | chr22_17597810_- | intronic |
| ADediting_965302 | chr22_17597813_- | intronic |
| ADediting_965303 | chr22_17597905_- | intronic |
| ADediting_965304 | chr22_17597906_- | intronic |
| ADediting_965305 | chr22_17597911_- | intronic |
| ADediting_965306 | chr22_17597912_- | intronic |
| ADediting_965307 | chr22_17597914_- | intronic |
| ADediting_965308 | chr22_17597923_- | intronic |
| ADediting_965309 | chr22_17597950_- | intronic |
| ADediting_965310 | chr22_17603169_- | intronic |
| ADediting_965311 | chr22_17603196_- | intronic |
| ADediting_965312 | chr22_17603621_- | intronic |
| ADediting_965313 | chr22_17603647_- | intronic |
| ADediting_965314 | chr22_17604553_- | intronic |
| ADediting_965315 | chr22_17604554_- | intronic |
| ADediting_965316 | chr22_17604625_- | intronic |
| ADediting_965317 | chr22_17604657_- | intronic |
| ADediting_965318 | chr22_17604687_- | intronic |
| ADediting_965319 | chr22_17604701_- | intronic |
| ADediting_965320 | chr22_17604732_- | intronic |
| ADediting_965321 | chr22_17604789_- | intronic |
| ADediting_965322 | chr22_17604790_- | intronic |
| ADediting_965323 | chr22_17605023_- | intronic |
| ADediting_965324 | chr22_17605050_- | intronic |
| ADediting_965325 | chr22_17605054_- | intronic |
| ADediting_965326 | chr22_17605069_- | intronic |
| ADediting_965327 | chr22_17605072_- | intronic |
| ADediting_965328 | chr22_17605093_- | intronic |
| ADediting_965329 | chr22_17605122_- | intronic |
| ADediting_965330 | chr22_17605123_- | intronic |
| ADediting_965331 | chr22_17605153_- | intronic |
| ADediting_965332 | chr22_17605368_- | intronic |
| ADediting_965333 | chr22_17605491_- | intronic |
| ADediting_965334 | chr22_17605728_- | intronic |
| ADediting_965335 | chr22_17605797_- | intronic |
| ADediting_965336 | chr22_17605859_- | intronic |
| ADediting_965337 | chr22_17605868_- | intronic |
| ADediting_965338 | chr22_17605873_- | intronic |
| ADediting_965339 | chr22_17605898_- | intronic |
| ADediting_965340 | chr22_17605933_- | intronic |
| ADediting_965341 | chr22_17605935_- | intronic |
| ADediting_965342 | chr22_17607243_- | intronic |
| ADediting_965343 | chr22_17607402_- | intronic |
| ADediting_965344 | chr22_17608687_- | intronic |
| ADediting_965345 | chr22_17608893_- | intronic |
| ADediting_965346 | chr22_17608897_- | intronic |
| ADediting_965347 | chr22_17608919_- | intronic |
| ADediting_965348 | chr22_17608937_- | intronic |
| ADediting_965349 | chr22_17608938_- | intronic |
| ADediting_965350 | chr22_17608974_- | intronic |
| ADediting_965351 | chr22_17609074_- | intronic |
| ADediting_965352 | chr22_17609196_- | intronic |
| ADediting_965353 | chr22_17609272_- | intronic |
| ADediting_965354 | chr22_17609299_- | intronic |
| ADediting_965355 | chr22_17609325_- | intronic |
| ADediting_965356 | chr22_17610031_- | intronic |
| ADediting_965357 | chr22_17610036_- | intronic |
| ADediting_965358 | chr22_17614188_- | intronic |
| ADediting_965359 | chr22_17614319_- | intronic |
| ADediting_965360 | chr22_17617895_- | intronic |
| ADediting_965361 | chr22_17617902_- | intronic |
| ADediting_965362 | chr22_17618029_- | intronic |
| ADediting_965363 | chr22_17618056_- | intronic |
| ADediting_965364 | chr22_17618082_- | intronic |
| ADediting_965365 | chr22_17618606_- | intronic |
| ADediting_965366 | chr22_17619718_- | intronic |
| ADediting_965367 | chr22_17620414_- | intronic |
| ADediting_965368 | chr22_17620419_- | intronic |
| ADediting_965369 | chr22_17625328_- | intronic |
| ADediting_965370 | chr22_17625396_- | intronic |
| ADediting_965371 | chr22_17625397_- | intronic |
| ADediting_965372 | chr22_17626117_- | intronic |
| ADediting_965373 | chr22_17626245_- | intronic |
| ADediting_965374 | chr22_17626264_- | intronic |
| ADediting_965375 | chr22_17626466_- | intronic |
| ADediting_965376 | chr22_17627402_- | intronic |
| ADediting_965377 | chr22_17627634_- | intronic |
| ADediting_965378 | chr22_17627656_- | intronic |
| ADediting_965379 | chr22_17627697_- | intronic |
| ADediting_965380 | chr22_17627699_- | intronic |
| ADediting_965381 | chr22_17627721_- | intronic |
| ADediting_965382 | chr22_17627739_- | intronic |
| ADediting_965383 | chr22_17627756_- | intronic |
| ADediting_965384 | chr22_17627780_- | intronic |
| ADediting_965385 | chr22_17627805_- | intronic |
| ADediting_965386 | chr22_17628103_- | intronic |
| ADediting_965387 | chr22_17628104_- | intronic |
| ADediting_965388 | chr22_17628130_- | intronic |
| ADediting_965389 | chr22_17628138_- | intronic |
| ADediting_965390 | chr22_17628168_- | intronic |
| ADediting_965391 | chr22_17628239_- | intronic |
| ADediting_1569462 | chr22_17595260_- | intronic |
| ADediting_1569463 | chr22_17595901_- | intronic |
| ADediting_1569464 | chr22_17597763_- | intronic |
| ADediting_1569465 | chr22_17597800_- | intronic |
| ADediting_1642046 | chr22_17608517_- | intronic |
| ADediting_1642047 | chr22_17608541_- | intronic |
| ADediting_1642048 | chr22_17626610_- | intronic |
| ADediting_1642049 | chr22_17626656_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_965226 | chr22_17592877_- | SINE | Alu | Name=AluY |
| ADediting_965227 | chr22_17592909_- | SINE | Alu | Name=AluY |
| ADediting_965228 | chr22_17592916_- | SINE | Alu | Name=AluY |
| ADediting_965229 | chr22_17592926_- | SINE | Alu | Name=AluY |
| ADediting_965230 | chr22_17592932_- | SINE | Alu | Name=AluY |
| ADediting_965231 | chr22_17592935_- | SINE | Alu | Name=AluY |
| ADediting_965232 | chr22_17592948_- | SINE | Alu | Name=AluY |
| ADediting_965233 | chr22_17592952_- | SINE | Alu | Name=AluY |
| ADediting_965234 | chr22_17592983_- | SINE | Alu | Name=AluY |
| ADediting_965235 | chr22_17592993_- | SINE | Alu | Name=AluY |
| ADediting_965236 | chr22_17594040_- | SINE | Alu | Name=AluSq |
| ADediting_965237 | chr22_17594080_- | SINE | Alu | Name=AluSq |
| ADediting_965238 | chr22_17594090_- | SINE | Alu | Name=AluSq |
| ADediting_965239 | chr22_17594182_- | SINE | Alu | Name=AluSq |
| ADediting_965240 | chr22_17595108_- | SINE | Alu | Name=AluSx1 |
| ADediting_965241 | chr22_17595113_- | SINE | Alu | Name=AluSx1 |
| ADediting_965242 | chr22_17595115_- | SINE | Alu | Name=AluSx1 |
| ADediting_965243 | chr22_17595116_- | SINE | Alu | Name=AluSx1 |
| ADediting_965244 | chr22_17595133_- | SINE | Alu | Name=AluSx1 |
| ADediting_965245 | chr22_17595144_- | SINE | Alu | Name=AluSx1 |
| ADediting_965246 | chr22_17595153_- | SINE | Alu | Name=AluSx1 |
| ADediting_965247 | chr22_17595159_- | SINE | Alu | Name=AluSx1 |
| ADediting_965248 | chr22_17595180_- | SINE | Alu | Name=AluSx1 |
| ADediting_965249 | chr22_17595185_- | SINE | Alu | Name=AluSx1 |
| ADediting_965250 | chr22_17595186_- | SINE | Alu | Name=AluSx1 |
| ADediting_965251 | chr22_17595196_- | SINE | Alu | Name=AluSx1 |
| ADediting_965252 | chr22_17595212_- | SINE | Alu | Name=AluSx1 |
| ADediting_965253 | chr22_17595216_- | SINE | Alu | Name=AluSx1 |
| ADediting_965254 | chr22_17595221_- | SINE | Alu | Name=AluSx1 |
| ADediting_965255 | chr22_17595250_- | SINE | Alu | Name=AluSx1 |
| ADediting_965256 | chr22_17595251_- | SINE | Alu | Name=AluSx1 |
| ADediting_965257 | chr22_17595263_- | SINE | Alu | Name=AluSx1 |
| ADediting_965258 | chr22_17595265_- | SINE | Alu | Name=AluSx1 |
| ADediting_965259 | chr22_17595266_- | SINE | Alu | Name=AluSx1 |
| ADediting_965260 | chr22_17595313_- | SINE | Alu | Name=AluSx1 |
| ADediting_965261 | chr22_17595314_- | SINE | Alu | Name=AluSx1 |
| ADediting_965262 | chr22_17595319_- | SINE | Alu | Name=AluSx1 |
| ADediting_965263 | chr22_17595320_- | SINE | Alu | Name=AluSx1 |
| ADediting_965264 | chr22_17595573_- | SINE | Alu | Name=AluSg |
| ADediting_965265 | chr22_17595649_- | SINE | Alu | Name=AluSg |
| ADediting_965266 | chr22_17595699_- | SINE | Alu | Name=AluSg |
| ADediting_965267 | chr22_17595794_- | SINE | Alu | Name=AluSg |
| ADediting_965268 | chr22_17595874_- | SINE | Alu | Name=AluY |
| ADediting_965269 | chr22_17595887_- | SINE | Alu | Name=AluY |
| ADediting_965270 | chr22_17595925_- | SINE | Alu | Name=AluY |
| ADediting_965271 | chr22_17595926_- | SINE | Alu | Name=AluY |
| ADediting_965272 | chr22_17595937_- | SINE | Alu | Name=AluY |
| ADediting_965273 | chr22_17595941_- | SINE | Alu | Name=AluY |
| ADediting_965274 | chr22_17595949_- | SINE | Alu | Name=AluY |
| ADediting_965275 | chr22_17595963_- | SINE | Alu | Name=AluY |
| ADediting_965276 | chr22_17596010_- | SINE | Alu | Name=AluY |
| ADediting_965277 | chr22_17596020_- | SINE | Alu | Name=AluY |
| ADediting_965278 | chr22_17596056_- | SINE | Alu | Name=AluY |
| ADediting_965279 | chr22_17596063_- | SINE | Alu | Name=AluY |
| ADediting_965280 | chr22_17596088_- | SINE | Alu | Name=AluY |
| ADediting_965281 | chr22_17596116_- | SINE | Alu | Name=AluY |
| ADediting_965282 | chr22_17596986_- | SINE | Alu | Name=AluSc8 |
| ADediting_965283 | chr22_17596998_- | SINE | Alu | Name=AluSc8 |
| ADediting_965284 | chr22_17597048_- | SINE | Alu | Name=AluSc8 |
| ADediting_965285 | chr22_17597052_- | SINE | Alu | Name=AluSc8 |
| ADediting_965286 | chr22_17597120_- | SINE | Alu | Name=AluSc8 |
| ADediting_965287 | chr22_17597130_- | SINE | Alu | Name=AluSc8 |
| ADediting_965288 | chr22_17597159_- | SINE | Alu | Name=AluSc8 |
| ADediting_965289 | chr22_17597160_- | SINE | Alu | Name=AluSc8 |
| ADediting_965290 | chr22_17597166_- | SINE | Alu | Name=AluSc8 |
| ADediting_965291 | chr22_17597198_- | SINE | Alu | Name=AluSc8 |
| ADediting_965292 | chr22_17597243_- | SINE | Alu | Name=AluSc8 |
| ADediting_965294 | chr22_17597657_- | SINE | Alu | Name=AluSc |
| ADediting_965295 | chr22_17597658_- | SINE | Alu | Name=AluSc |
| ADediting_965296 | chr22_17597723_- | SINE | Alu | Name=AluSc |
| ADediting_965297 | chr22_17597742_- | SINE | Alu | Name=AluSc |
| ADediting_965298 | chr22_17597769_- | SINE | Alu | Name=AluSc |
| ADediting_965299 | chr22_17597795_- | SINE | Alu | Name=AluSc |
| ADediting_965300 | chr22_17597804_- | SINE | Alu | Name=AluSc |
| ADediting_965301 | chr22_17597810_- | SINE | Alu | Name=AluSc |
| ADediting_965302 | chr22_17597813_- | SINE | Alu | Name=AluSc |
| ADediting_965303 | chr22_17597905_- | SINE | Alu | Name=AluSc |
| ADediting_965304 | chr22_17597906_- | SINE | Alu | Name=AluSc |
| ADediting_965305 | chr22_17597911_- | SINE | Alu | Name=AluSc |
| ADediting_965306 | chr22_17597912_- | SINE | Alu | Name=AluSc |
| ADediting_965307 | chr22_17597914_- | SINE | Alu | Name=AluSc |
| ADediting_965308 | chr22_17597923_- | SINE | Alu | Name=AluSc |
| ADediting_965309 | chr22_17597950_- | SINE | Alu | Name=AluSc |
| ADediting_965310 | chr22_17603169_- | SINE | Alu | Name=AluSz |
| ADediting_965311 | chr22_17603196_- | SINE | Alu | Name=AluSz |
| ADediting_965312 | chr22_17603621_- | SINE | Alu | Name=AluJb |
| ADediting_965313 | chr22_17603647_- | SINE | Alu | Name=AluJb |
| ADediting_965314 | chr22_17604553_- | SINE | Alu | Name=AluSx3 |
| ADediting_965315 | chr22_17604554_- | SINE | Alu | Name=AluSx3 |
| ADediting_965316 | chr22_17604625_- | SINE | Alu | Name=AluSx3 |
| ADediting_965317 | chr22_17604657_- | SINE | Alu | Name=AluSx3 |
| ADediting_965318 | chr22_17604687_- | SINE | Alu | Name=AluSx3 |
| ADediting_965319 | chr22_17604701_- | SINE | Alu | Name=AluSx3 |
| ADediting_965320 | chr22_17604732_- | SINE | Alu | Name=AluSx3 |
| ADediting_965321 | chr22_17604789_- | SINE | Alu | Name=AluSx3 |
| ADediting_965322 | chr22_17604790_- | SINE | Alu | Name=AluSx3 |
| ADediting_965323 | chr22_17605023_- | SINE | Alu | Name=AluSq10 |
| ADediting_965324 | chr22_17605050_- | SINE | Alu | Name=AluSq10 |
| ADediting_965325 | chr22_17605054_- | SINE | Alu | Name=AluSq10 |
| ADediting_965326 | chr22_17605069_- | SINE | Alu | Name=AluSq10 |
| ADediting_965327 | chr22_17605072_- | SINE | Alu | Name=AluSq10 |
| ADediting_965328 | chr22_17605093_- | SINE | Alu | Name=AluSq10 |
| ADediting_965329 | chr22_17605122_- | SINE | Alu | Name=AluSq10 |
| ADediting_965330 | chr22_17605123_- | SINE | Alu | Name=AluSq10 |
| ADediting_965331 | chr22_17605153_- | SINE | Alu | Name=AluSq10 |
| ADediting_965332 | chr22_17605368_- | SINE | Alu | Name=AluSp |
| ADediting_965333 | chr22_17605491_- | SINE | Alu | Name=AluSp |
| ADediting_965334 | chr22_17605728_- | SINE | Alu | Name=AluJo |
| ADediting_965335 | chr22_17605797_- | SINE | Alu | Name=AluJo |
| ADediting_965336 | chr22_17605859_- | SINE | Alu | Name=AluJo |
| ADediting_965337 | chr22_17605868_- | SINE | Alu | Name=AluJo |
| ADediting_965338 | chr22_17605873_- | SINE | Alu | Name=AluJo |
| ADediting_965339 | chr22_17605898_- | SINE | Alu | Name=AluJo |
| ADediting_965340 | chr22_17605933_- | SINE | Alu | Name=AluJo |
| ADediting_965341 | chr22_17605935_- | SINE | Alu | Name=AluJo |
| ADediting_965342 | chr22_17607243_- | SINE | Alu | Name=AluSc5 |
| ADediting_965343 | chr22_17607402_- | SINE | Alu | Name=AluSc5 |
| ADediting_965344 | chr22_17608687_- | SINE | Alu | Name=AluJr |
| ADediting_965345 | chr22_17608893_- | SINE | Alu | Name=AluY |
| ADediting_965346 | chr22_17608897_- | SINE | Alu | Name=AluY |
| ADediting_965347 | chr22_17608919_- | SINE | Alu | Name=AluY |
| ADediting_965348 | chr22_17608937_- | SINE | Alu | Name=AluY |
| ADediting_965349 | chr22_17608938_- | SINE | Alu | Name=AluY |
| ADediting_965350 | chr22_17608974_- | SINE | Alu | Name=AluY |
| ADediting_965351 | chr22_17609074_- | SINE | Alu | Name=AluY |
| ADediting_965352 | chr22_17609196_- | SINE | Alu | Name=AluSx1 |
| ADediting_965353 | chr22_17609272_- | SINE | Alu | Name=AluSx1 |
| ADediting_965354 | chr22_17609299_- | SINE | Alu | Name=AluSx1 |
| ADediting_965355 | chr22_17609325_- | SINE | Alu | Name=AluSx1 |
| ADediting_965356 | chr22_17610031_- | SINE | Alu | Name=AluJr |
| ADediting_965357 | chr22_17610036_- | SINE | Alu | Name=AluJr |
| ADediting_965358 | chr22_17614188_- | SINE | Alu | Name=AluSp |
| ADediting_965359 | chr22_17614319_- | SINE | Alu | Name=AluSp |
| ADediting_965360 | chr22_17617895_- | SINE | Alu | Name=AluSx |
| ADediting_965361 | chr22_17617902_- | SINE | Alu | Name=AluSx |
| ADediting_965362 | chr22_17618029_- | SINE | Alu | Name=AluSx |
| ADediting_965363 | chr22_17618056_- | SINE | Alu | Name=AluSx |
| ADediting_965364 | chr22_17618082_- | SINE | Alu | Name=AluSx |
| ADediting_965365 | chr22_17618606_- | SINE | Alu | Name=AluY |
| ADediting_965366 | chr22_17619718_- | SINE | Alu | Name=AluJr4 |
| ADediting_965367 | chr22_17620414_- | SINE | Alu | Name=AluY |
| ADediting_965368 | chr22_17620419_- | SINE | Alu | Name=AluY |
| ADediting_965369 | chr22_17625328_- | SINE | Alu | Name=AluSp |
| ADediting_965370 | chr22_17625396_- | SINE | Alu | Name=AluSp |
| ADediting_965371 | chr22_17625397_- | SINE | Alu | Name=AluSp |
| ADediting_965372 | chr22_17626117_- | SINE | Alu | Name=AluY |
| ADediting_965373 | chr22_17626245_- | SINE | Alu | Name=AluY |
| ADediting_965374 | chr22_17626264_- | SINE | Alu | Name=AluY |
| ADediting_965375 | chr22_17626466_- | SINE | Alu | Name=AluJr |
| ADediting_965376 | chr22_17627402_- | SINE | Alu | Name=AluSx1 |
| ADediting_965377 | chr22_17627634_- | SINE | Alu | Name=AluSx |
| ADediting_965378 | chr22_17627656_- | SINE | Alu | Name=AluSx |
| ADediting_965379 | chr22_17627697_- | SINE | Alu | Name=AluSx |
| ADediting_965380 | chr22_17627699_- | SINE | Alu | Name=AluSx |
| ADediting_965381 | chr22_17627721_- | SINE | Alu | Name=AluSx |
| ADediting_965382 | chr22_17627739_- | SINE | Alu | Name=AluSx |
| ADediting_965383 | chr22_17627756_- | SINE | Alu | Name=AluSx |
| ADediting_965384 | chr22_17627780_- | SINE | Alu | Name=AluSx |
| ADediting_965385 | chr22_17627805_- | SINE | Alu | Name=AluSx |
| ADediting_965386 | chr22_17628103_- | SINE | Alu | Name=AluSx |
| ADediting_965387 | chr22_17628104_- | SINE | Alu | Name=AluSx |
| ADediting_965388 | chr22_17628130_- | SINE | Alu | Name=AluSx |
| ADediting_965389 | chr22_17628138_- | SINE | Alu | Name=AluSx |
| ADediting_965390 | chr22_17628168_- | SINE | Alu | Name=AluSx |
| ADediting_965391 | chr22_17628239_- | SINE | Alu | Name=AluSx |
| ADediting_1569462 | chr22_17595260_- | SINE | Alu | Name=AluSx1 |
| ADediting_1569463 | chr22_17595901_- | SINE | Alu | Name=AluY |
| ADediting_1569464 | chr22_17597763_- | SINE | Alu | Name=AluSc |
| ADediting_1569465 | chr22_17597800_- | SINE | Alu | Name=AluSc |
| ADediting_1642046 | chr22_17608517_- | SINE | Alu | Name=AluJr |
| ADediting_1642047 | chr22_17608541_- | SINE | Alu | Name=AluJr |
| ADediting_1642048 | chr22_17626610_- | SINE | Alu | Name=AluSx |
| ADediting_1642049 | chr22_17626656_- | SINE | Alu | Name=AluSx |
Top |
RNA A-to-I editing events in the alternative splicing sites for ATP6V1E1 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for ATP6V1E1 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for ATP6V1E1 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for ATP6V1E1 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337757 | chr7_5495852_- | ENSG00000131100.13 | ENST00000253413.10 | ATP6V1E1-201 | hsa-miR-589-3p | chr22 | 17592558 | 17592564 | 7mer-m8 | 17592557 | 17592579 | 154 | -20.18 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000131100.13 | ENST00000399796.6 | ATP6V1E1-202 | hsa-miR-589-3p | chr22 | 17592558 | 17592564 | 7mer-m8 | 17592557 | 17592579 | 154 | -20.18 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000131100.13 | ENST00000399798.6 | ATP6V1E1-203 | hsa-miR-589-3p | chr22 | 17592558 | 17592564 | 7mer-m8 | 17592557 | 17592579 | 154 | -20.18 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000131100.13 | ENST00000253413.10 | ATP6V1E1-201 | hsa-miR-641 | chr22 | 17592593 | 17592599 | 7mer-m8 | 17592592 | 17592615 | 140 | -12.8 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000131100.13 | ENST00000399796.6 | ATP6V1E1-202 | hsa-miR-641 | chr22 | 17592593 | 17592599 | 7mer-m8 | 17592592 | 17592615 | 140 | -12.8 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000131100.13 | ENST00000399798.6 | ATP6V1E1-203 | hsa-miR-641 | chr22 | 17592593 | 17592599 | 7mer-m8 | 17592592 | 17592615 | 140 | -12.8 |
| ADediting_286380 | chr11_79422188_- | ENSG00000131100.13 | ENST00000253413.10 | ATP6V1E1-201 | hsa-miR-5579-3p | chr22 | 17592204 | 17592210 | 7mer-m8 | 17592203 | 17592224 | 140 | -11.26 |
| ADediting_286380 | chr11_79422188_- | ENSG00000131100.13 | ENST00000399796.6 | ATP6V1E1-202 | hsa-miR-5579-3p | chr22 | 17592204 | 17592210 | 7mer-m8 | 17592203 | 17592224 | 140 | -11.26 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| Differentially expressed gene-miRNA network |
Top |
The effects of the RNA editing to the stability of the RNA structures for ATP6V1E1 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
Top |
Relation with ADAR for ATP6V1E1 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_965239 | chr22_17594182_- | 0.0053470414882975 | 0.157841882083982 | 0.444637233728575 | 0.043569599350662 | 1.01964681782065e-10 | 0.356442384086809 |
| DLPFC | ADediting_965265 | chr22_17595649_- | 0.0672369609477269 | 0.104079941269681 | 0.735227856721197 | 0.0192834241448684 | 9.81022047052381e-11 | 0.356742887477437 |
| DLPFC | ADediting_965278 | chr22_17596056_- | 0.000561077956283416 | 0.19483944931147 | 0.0781438042932939 | 0.100202686621143 | 8.15803727725984e-12 | 0.375464591816598 |
| DLPFC | ADediting_965279 | chr22_17596063_- | 0.0116232456794602 | 0.143157787168112 | 0.359080058257713 | 0.0522644102857755 | 5.09236501234548e-10 | 0.343637061463633 |
| DLPFC | ADediting_965285 | chr22_17597052_- | 0.348269346587484 | 0.0534498988574867 | 0.491491332007994 | -0.0392156865437896 | 1.42088890590348e-08 | 0.315113365905126 |
| DLPFC | ADediting_965302 | chr22_17597813_- | 0.350605131784901 | 0.0531918180795048 | 0.212635466358095 | -0.0709854295051827 | 6.80853539377626e-10 | 0.341261571404005 |
| DLPFC | ADediting_965305 | chr22_17597911_- | 0.148907183249629 | 0.0821729986745281 | 0.537621920097082 | 0.0351410568942662 | 1.36596562205319e-08 | 0.315469089335609 |
| DLPFC | ADediting_965321 | chr22_17604789_- | 0.67793708636153 | 0.0236786563545043 | 0.326482809732325 | -0.0559119832371801 | 1.87481446131049e-12 | 0.385993006880446 |
| DLPFC | ADediting_965322 | chr22_17604790_- | 0.182210920335956 | 0.0759622439421184 | 0.790119080117059 | -0.0151770851194302 | 1.7307055586283e-14 | 0.417239926580267 |
| DLPFC | ADediting_965329 | chr22_17605122_- | 0.15318377179985 | 0.0813203807383017 | 0.918025110978535 | 0.00586921994026624 | 4.22123255553867e-14 | 0.411540030883871 |
| DLPFC | ADediting_965345 | chr22_17608893_- | 0.140337820008994 | 0.0839391466456678 | 0.603307377965873 | -0.0296273574157914 | 3.27202299965777e-17 | 0.454552131313602 |
| DLPFC | ADediting_965346 | chr22_17608897_- | 0.0530286247132982 | 0.109993600372444 | 0.643684865089303 | -0.0263732113356733 | 8.10076964300293e-13 | 0.391836374593514 |
| DLPFC | ADediting_965350 | chr22_17608974_- | 0.637717661757051 | 0.0268485238861032 | 0.0473014218346126 | -0.112756397708944 | 5.26336653520224e-24 | 0.531543571391652 |
| DLPFC | ADediting_965351 | chr22_17609074_- | 0.217290745762512 | 0.0702703267092768 | 0.269250848770969 | -0.0629398527105332 | 4.20034997749226e-10 | 0.345201178399436 |
| DLPFC | ADediting_965355 | chr22_17609325_- | 0.372840746654109 | 0.0507872581904163 | 0.0379569396415446 | -0.117935011509594 | 5.73419210632782e-19 | 0.476395029467863 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 5.5312516100031e-80 | 0.829723812512987 | 1.86812060520171e-95 | 0.867590621138599 | 0.935764163310273 | 0.00459602244752836 |
| AC | 2.56253826198577e-101 | 0.917551411515392 | 3.53777221892184e-81 | 0.877656837611872 | 9.77851897677596e-07 | 0.303824677089128 |
| PCC | 8.02069140668372e-48 | 0.820697624909871 | 1.96503670710314e-52 | 0.841522224967367 | 0.27719853372684 | 0.0790217874006932 |
| CER | 6.43365269711427e-20 | 0.657372689060391 | 5.12394536904277e-09 | 0.454554904677969 | 0.712540757389159 | -0.0303302875608815 |
| TCX | 7.71637102044295e-28 | 0.745286822928 | 2.98068123417779e-22 | 0.68674368306239 | 0.0985640367399597 | -0.135384275799779 |
| FP | 7.71045826906926e-11 | 0.46292633631497 | 6.59360666006687e-16 | 0.557211966764006 | 0.0267606197762663 | -0.166036333948105 |
| IFG | 0.0329435894107386 | 0.427711776929665 | 0.301713696789661 | 0.215135948535402 | 0.0536820980864005 | -0.390394403829826 |
| PG | 2.45819180736275e-34 | 0.746122321669807 | 1.4073244702074e-23 | 0.648530973069076 | 0.023649448751418 | -0.16588193008679 |
| STG | 6.84941260866028e-19 | 0.787129786078384 | 2.89737212306875e-14 | 0.712635131883385 | 0.225401040320021 | -0.133680204342391 |
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Relation with AD stages for ATP6V1E1 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
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RelatedDrugs for ATP6V1E1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ATP6V1E1 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| ATP6V1E1 | C4479387 | CUTIS LAXA, AUTOSOMAL RECESSIVE, TYPE IIC | 1 | CTD_human;ORPHANET;UNIPROT |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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