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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for PIGH |
 Gene summary |
| Gene information | Gene symbol | PIGH | Gene ID | 5283 |
| Gene name | phosphatidylinositol glycan anchor biosynthesis class H | |
| Synonyms | GPI-H | |
| Cytomap | 14q24.1 | |
| Type of gene | protein-coding | |
| Description | phosphatidylinositol N-acetylglucosaminyltransferase subunit Hphosphatidylinositol-glycan biosynthesis, class H protein | |
| Modification date | 20200313 | |
| UniProtAcc | Q14442, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
RNA A-to-I events for PIGH |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_442797(67590349, -), ADediting_442798(67590367, -), ADediting_442799(67590390, -), ADediting_442800(67590391, -), ADediting_442801(67590614, -), ADediting_442802(67591624, -), ADediting_442803(67591629, -), ADediting_442804(67591652, -), ADediting_442805(67591691, -), ADediting_442806(67591696, -), ADediting_442807(67591727, -), ADediting_442808(67591760, -), ADediting_442809(67591807, -), ADediting_442810(67591808, -), ADediting_442811(67592175, -), ADediting_442812(67592178, -), ADediting_442813(67592217, -), ADediting_442814(67592223, -), ADediting_442815(67592237, -), ADediting_442816(67592262, -), ADediting_442817(67592272, -), ADediting_442818(67592316, -), ADediting_442819(67592318, -), ADediting_442820(67592354, -), ADediting_442821(67592357, -), ADediting_442822(67592358, -), ADediting_442823(67592364, -), ADediting_442824(67592371, -), ADediting_442825(67592378, -), ADediting_442826(67592387, -), ADediting_442827(67592416, -), ADediting_442828(67592424, -), ADediting_442829(67592430, -), ADediting_442830(67592432, -), ADediting_442831(67592823, -), ADediting_442832(67592824, -), ADediting_442833(67592853, -), ADediting_442834(67592871, -), ADediting_442835(67592882, -), ADediting_442836(67592897, -), ADediting_442837(67592923, -), ADediting_442838(67592933, -), ADediting_442839(67592965, -), ADediting_442840(67592966, -), ADediting_442841(67592969, -), ADediting_442842(67593000, -), ADediting_442843(67593020, -), ADediting_442844(67593054, -), ADediting_442845(67593060, -), ADediting_442846(67593233, -), ADediting_442847(67593238, -), ADediting_442848(67593245, -), ADediting_442849(67593268, -), ADediting_442850(67593272, -), ADediting_442851(67593273, -), ADediting_442852(67593324, -), ADediting_442853(67593363, -), ADediting_442854(67593369, -), ADediting_442855(67593379, -), ADediting_442856(67593396, -), ADediting_442857(67593408, -), ADediting_442858(67593429, -), ADediting_442859(67593439, -), ADediting_442860(67594266, -), ADediting_442861(67594318, -), ADediting_442862(67594398, -), ADediting_442863(67594481, -), ADediting_442864(67594525, -), ADediting_442865(67594564, -), ADediting_442866(67594615, -), ADediting_442867(67595015, -), ADediting_442868(67596191, -), ADediting_442869(67596225, -), ADediting_442870(67596231, -), ADediting_442871(67596244, -), ADediting_442872(67596257, -), ADediting_442873(67596266, -), ADediting_442874(67596267, -), ADediting_442875(67596340, -), ADediting_442876(67596344, -), ADediting_442877(67596350, -), ADediting_442878(67596420, -), ADediting_442879(67597215, -), ADediting_442880(67597312, -), ADediting_442881(67597330, -), ADediting_442882(67597354, -), ADediting_442883(67597366, -), ADediting_442884(67597395, -), ADediting_442885(67597396, -), ADediting_442886(67597416, -), ADediting_442887(67597418, -), ADediting_442888(67597464, -), ADediting_442889(67598947, -), ADediting_442890(67598965, -), ADediting_442891(67598996, -), ADediting_1537437(67590523, -), ADediting_1537438(67590532, -), ADediting_1537439(67590538, -), ADediting_1537440(67590541, -), ADediting_1537441(67590552, -), ADediting_1537442(67590632, -), ADediting_1537443(67590788, -), ADediting_1537444(67591640, -), ADediting_1537445(67591664, -), ADediting_1537446(67591688, -), ADediting_1537447(67591699, -), ADediting_1537448(67591728, -), ADediting_1537449(67591736, -), ADediting_1537450(67591746, -), ADediting_1537451(67591765, -), ADediting_1537452(67591770, -), ADediting_1537453(67592213, -), ADediting_1537454(67592214, -), ADediting_1537455(67592252, -), ADediting_1537456(67592269, -), ADediting_1537457(67592308, -), ADediting_1537458(67592328, -), ADediting_1537459(67592353, -), ADediting_1537460(67592355, -), ADediting_1537461(67592393, -), ADediting_1537462(67592405, -), ADediting_1537463(67592821, -), ADediting_1537464(67592858, -), ADediting_1537465(67592954, -), ADediting_1537466(67593059, -), ADediting_1537467(67593298, -), ADediting_1537468(67593316, -), ADediting_1537469(67593333, -), ADediting_1537470(67593367, -), ADediting_1537471(67593391, -), ADediting_1537472(67593415, -), ADediting_1537473(67593422, -), ADediting_1537474(67593434, -), ADediting_1537475(67593453, -), ADediting_1620008(67597350, -), |
Top |
RNA editing positional annotations for PIGH using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| ADediting_1537455 | chr14_67592252_- | nonsynonymous SNV | ENST00000559581.5 | c.A542G | p.H181R | 0.019 | . | -4.53 |
| ADediting_1537456 | chr14_67592269_- | synonymous SNV | ENST00000559581.5 | c.A525G | p.V175V | . | . | . |
| ADediting_1537457 | chr14_67592308_- | synonymous SNV | ENST00000559581.5 | c.A486G | p.A162A | . | . | . |
| ADediting_1537458 | chr14_67592328_- | nonsynonymous SNV | ENST00000559581.5 | c.A466G | p.T156A | 0.007 | . | -0.14 |
| ADediting_1537459 | chr14_67592353_- | synonymous SNV | ENST00000559581.5 | c.A441G | p.K147K | . | . | . |
| ADediting_1537460 | chr14_67592355_- | nonsynonymous SNV | ENST00000559581.5 | c.A439G | p.K147E | 0.129 | . | -0.72 |
| ADediting_1537461 | chr14_67592393_- | nonsynonymous SNV | ENST00000559581.5 | c.A401G | p.N134S | 0.527 | . | -0.6 |
| ADediting_1537462 | chr14_67592405_- | nonsynonymous SNV | ENST00000559581.5 | c.A389G | p.E130G | 0.082 | . | -0.24 |
| ADediting_1537462 | chr14_67592405_- | nonsynonymous SNV | ENST00000559415.1 | c.A410G | p.E137G | 0.082 | . | -0.24 |
| ADediting_442816 | chr14_67592262_- | nonsynonymous SNV | ENST00000559581.5 | c.A532G | p.R178G | 1.0 | . | 4.0 |
| ADediting_442817 | chr14_67592272_- | synonymous SNV | ENST00000559581.5 | c.A522G | p.L174L | . | . | . |
| ADediting_442818 | chr14_67592316_- | nonsynonymous SNV | ENST00000559581.5 | c.A478G | p.R160G | 0.004 | . | -4.7 |
| ADediting_442819 | chr14_67592318_- | nonsynonymous SNV | ENST00000559581.5 | c.A476G | p.Y159C | 0.0 | . | -6.01 |
| ADediting_442820 | chr14_67592354_- | nonsynonymous SNV | ENST00000559581.5 | c.A440G | p.K147R | 1.0 | . | 1.05 |
| ADediting_442821 | chr14_67592357_- | nonsynonymous SNV | ENST00000559581.5 | c.A437G | p.K146R | 0.051 | . | -2.01 |
| ADediting_442822 | chr14_67592358_- | nonsynonymous SNV | ENST00000559581.5 | c.A436G | p.K146E | 0.007 | . | -2.65 |
| ADediting_442823 | chr14_67592364_- | nonsynonymous SNV | ENST00000559581.5 | c.A430G | p.R144G | 0.18 | . | 0.25 |
| ADediting_442824 | chr14_67592371_- | synonymous SNV | ENST00000559581.5 | c.A423G | p.P141P | . | . | . |
| ADediting_442825 | chr14_67592378_- | nonsynonymous SNV | ENST00000559581.5 | c.A416G | p.Q139R | 0.015 | . | -2.96 |
| ADediting_442826 | chr14_67592387_- | nonsynonymous SNV | ENST00000559581.5 | c.A407G | p.H136R | 0.559 | . | 1.01 |
| ADediting_442827 | chr14_67592416_- | synonymous SNV | ENST00000559581.5 | c.A378G | p.S126S | . | . | . |
| ADediting_442827 | chr14_67592416_- | synonymous SNV | ENST00000559415.1 | c.A399G | p.S133S | . | . | . |
| ADediting_442828 | chr14_67592424_- | nonsynonymous SNV | ENST00000559581.5 | c.A370G | p.T124A | 0.176 | . | 0.47 |
| ADediting_442828 | chr14_67592424_- | nonsynonymous SNV | ENST00000559415.1 | c.A391G | p.T131A | 0.176 | . | 0.47 |
| ADediting_442829 | chr14_67592430_- | nonsynonymous SNV | ENST00000559581.5 | c.A364G | p.S122G | 0.22 | . | -1.0 |
| ADediting_442829 | chr14_67592430_- | nonsynonymous SNV | ENST00000559415.1 | c.A385G | p.S129G | 0.22 | . | -1.0 |
| ADediting_442830 | chr14_67592432_- | nonsynonymous SNV | ENST00000559581.5 | c.A362G | p.Q121R | 0.344 | . | -0.11 |
| ADediting_442830 | chr14_67592432_- | nonsynonymous SNV | ENST00000559415.1 | c.A383G | p.Q128R | 0.344 | . | -0.11 |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_442797 | chr14_67590349_- | intronic |
| ADediting_442798 | chr14_67590367_- | intronic |
| ADediting_442799 | chr14_67590390_- | intronic |
| ADediting_442800 | chr14_67590391_- | intronic |
| ADediting_442801 | chr14_67590614_- | intronic |
| ADediting_442802 | chr14_67591624_- | intronic |
| ADediting_442803 | chr14_67591629_- | intronic |
| ADediting_442804 | chr14_67591652_- | intronic |
| ADediting_442805 | chr14_67591691_- | intronic |
| ADediting_442806 | chr14_67591696_- | intronic |
| ADediting_442807 | chr14_67591727_- | intronic |
| ADediting_442808 | chr14_67591760_- | intronic |
| ADediting_442809 | chr14_67591807_- | intronic |
| ADediting_442810 | chr14_67591808_- | intronic |
| ADediting_442811 | chr14_67592175_- | UTR3 |
| ADediting_442812 | chr14_67592178_- | UTR3 |
| ADediting_442813 | chr14_67592217_- | UTR3 |
| ADediting_442814 | chr14_67592223_- | UTR3 |
| ADediting_442815 | chr14_67592237_- | UTR3 |
| ADediting_442816 | chr14_67592262_- | exonic |
| ADediting_442817 | chr14_67592272_- | exonic |
| ADediting_442818 | chr14_67592316_- | exonic |
| ADediting_442819 | chr14_67592318_- | exonic |
| ADediting_442820 | chr14_67592354_- | exonic |
| ADediting_442821 | chr14_67592357_- | exonic |
| ADediting_442822 | chr14_67592358_- | exonic |
| ADediting_442823 | chr14_67592364_- | exonic |
| ADediting_442824 | chr14_67592371_- | exonic |
| ADediting_442825 | chr14_67592378_- | exonic |
| ADediting_442826 | chr14_67592387_- | exonic |
| ADediting_442827 | chr14_67592416_- | exonic |
| ADediting_442828 | chr14_67592424_- | exonic |
| ADediting_442829 | chr14_67592430_- | exonic |
| ADediting_442830 | chr14_67592432_- | exonic |
| ADediting_442831 | chr14_67592823_- | intronic |
| ADediting_442832 | chr14_67592824_- | intronic |
| ADediting_442833 | chr14_67592853_- | intronic |
| ADediting_442834 | chr14_67592871_- | intronic |
| ADediting_442835 | chr14_67592882_- | intronic |
| ADediting_442836 | chr14_67592897_- | intronic |
| ADediting_442837 | chr14_67592923_- | intronic |
| ADediting_442838 | chr14_67592933_- | intronic |
| ADediting_442839 | chr14_67592965_- | intronic |
| ADediting_442840 | chr14_67592966_- | intronic |
| ADediting_442841 | chr14_67592969_- | intronic |
| ADediting_442842 | chr14_67593000_- | intronic |
| ADediting_442843 | chr14_67593020_- | intronic |
| ADediting_442844 | chr14_67593054_- | intronic |
| ADediting_442845 | chr14_67593060_- | intronic |
| ADediting_442846 | chr14_67593233_- | intronic |
| ADediting_442847 | chr14_67593238_- | intronic |
| ADediting_442848 | chr14_67593245_- | intronic |
| ADediting_442849 | chr14_67593268_- | intronic |
| ADediting_442850 | chr14_67593272_- | intronic |
| ADediting_442851 | chr14_67593273_- | intronic |
| ADediting_442852 | chr14_67593324_- | intronic |
| ADediting_442853 | chr14_67593363_- | intronic |
| ADediting_442854 | chr14_67593369_- | intronic |
| ADediting_442855 | chr14_67593379_- | intronic |
| ADediting_442856 | chr14_67593396_- | intronic |
| ADediting_442857 | chr14_67593408_- | intronic |
| ADediting_442858 | chr14_67593429_- | intronic |
| ADediting_442859 | chr14_67593439_- | intronic |
| ADediting_442860 | chr14_67594266_- | intronic |
| ADediting_442861 | chr14_67594318_- | intronic |
| ADediting_442862 | chr14_67594398_- | intronic |
| ADediting_442863 | chr14_67594481_- | intronic |
| ADediting_442864 | chr14_67594525_- | intronic |
| ADediting_442865 | chr14_67594564_- | intronic |
| ADediting_442866 | chr14_67594615_- | intronic |
| ADediting_442867 | chr14_67595015_- | intronic |
| ADediting_442868 | chr14_67596191_- | intronic |
| ADediting_442869 | chr14_67596225_- | intronic |
| ADediting_442870 | chr14_67596231_- | intronic |
| ADediting_442871 | chr14_67596244_- | intronic |
| ADediting_442872 | chr14_67596257_- | intronic |
| ADediting_442873 | chr14_67596266_- | intronic |
| ADediting_442874 | chr14_67596267_- | intronic |
| ADediting_442875 | chr14_67596340_- | intronic |
| ADediting_442876 | chr14_67596344_- | intronic |
| ADediting_442877 | chr14_67596350_- | intronic |
| ADediting_442878 | chr14_67596420_- | intronic |
| ADediting_442879 | chr14_67597215_- | intronic |
| ADediting_442880 | chr14_67597312_- | intronic |
| ADediting_442881 | chr14_67597330_- | intronic |
| ADediting_442882 | chr14_67597354_- | intronic |
| ADediting_442883 | chr14_67597366_- | intronic |
| ADediting_442884 | chr14_67597395_- | intronic |
| ADediting_442885 | chr14_67597396_- | intronic |
| ADediting_442886 | chr14_67597416_- | intronic |
| ADediting_442887 | chr14_67597418_- | intronic |
| ADediting_442888 | chr14_67597464_- | intronic |
| ADediting_442889 | chr14_67598947_- | intronic |
| ADediting_442890 | chr14_67598965_- | intronic |
| ADediting_442891 | chr14_67598996_- | intronic |
| ADediting_1537437 | chr14_67590523_- | intronic |
| ADediting_1537438 | chr14_67590532_- | intronic |
| ADediting_1537439 | chr14_67590538_- | intronic |
| ADediting_1537440 | chr14_67590541_- | intronic |
| ADediting_1537441 | chr14_67590552_- | intronic |
| ADediting_1537442 | chr14_67590632_- | intronic |
| ADediting_1537443 | chr14_67590788_- | intronic |
| ADediting_1537444 | chr14_67591640_- | intronic |
| ADediting_1537445 | chr14_67591664_- | intronic |
| ADediting_1537446 | chr14_67591688_- | intronic |
| ADediting_1537447 | chr14_67591699_- | intronic |
| ADediting_1537448 | chr14_67591728_- | intronic |
| ADediting_1537449 | chr14_67591736_- | intronic |
| ADediting_1537450 | chr14_67591746_- | intronic |
| ADediting_1537451 | chr14_67591765_- | intronic |
| ADediting_1537452 | chr14_67591770_- | intronic |
| ADediting_1537453 | chr14_67592213_- | UTR3 |
| ADediting_1537454 | chr14_67592214_- | UTR3 |
| ADediting_1537455 | chr14_67592252_- | exonic |
| ADediting_1537456 | chr14_67592269_- | exonic |
| ADediting_1537457 | chr14_67592308_- | exonic |
| ADediting_1537458 | chr14_67592328_- | exonic |
| ADediting_1537459 | chr14_67592353_- | exonic |
| ADediting_1537460 | chr14_67592355_- | exonic |
| ADediting_1537461 | chr14_67592393_- | exonic |
| ADediting_1537462 | chr14_67592405_- | exonic |
| ADediting_1537463 | chr14_67592821_- | intronic |
| ADediting_1537464 | chr14_67592858_- | intronic |
| ADediting_1537465 | chr14_67592954_- | intronic |
| ADediting_1537466 | chr14_67593059_- | intronic |
| ADediting_1537467 | chr14_67593298_- | intronic |
| ADediting_1537468 | chr14_67593316_- | intronic |
| ADediting_1537469 | chr14_67593333_- | intronic |
| ADediting_1537470 | chr14_67593367_- | intronic |
| ADediting_1537471 | chr14_67593391_- | intronic |
| ADediting_1537472 | chr14_67593415_- | intronic |
| ADediting_1537473 | chr14_67593422_- | intronic |
| ADediting_1537474 | chr14_67593434_- | intronic |
| ADediting_1537475 | chr14_67593453_- | intronic |
| ADediting_1620008 | chr14_67597350_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_442797 | chr14_67590349_- | SINE | Alu | Name=AluSx1 |
| ADediting_442798 | chr14_67590367_- | SINE | Alu | Name=AluSx1 |
| ADediting_442799 | chr14_67590390_- | SINE | Alu | Name=AluSx1 |
| ADediting_442800 | chr14_67590391_- | SINE | Alu | Name=AluSx1 |
| ADediting_442801 | chr14_67590614_- | SINE | Alu | Name=AluSz6 |
| ADediting_442802 | chr14_67591624_- | SINE | Alu | Name=AluJb |
| ADediting_442803 | chr14_67591629_- | SINE | Alu | Name=AluJb |
| ADediting_442804 | chr14_67591652_- | SINE | Alu | Name=AluJb |
| ADediting_442805 | chr14_67591691_- | SINE | Alu | Name=AluJb |
| ADediting_442806 | chr14_67591696_- | SINE | Alu | Name=AluJb |
| ADediting_442807 | chr14_67591727_- | SINE | Alu | Name=AluJb |
| ADediting_442808 | chr14_67591760_- | SINE | Alu | Name=AluJb |
| ADediting_442809 | chr14_67591807_- | SINE | Alu | Name=AluJb |
| ADediting_442810 | chr14_67591808_- | SINE | Alu | Name=AluJb |
| ADediting_442811 | chr14_67592175_- | SINE | Alu | Name=AluJb |
| ADediting_442812 | chr14_67592178_- | SINE | Alu | Name=AluJb |
| ADediting_442813 | chr14_67592217_- | SINE | Alu | Name=AluJb |
| ADediting_442814 | chr14_67592223_- | SINE | Alu | Name=AluJb |
| ADediting_442815 | chr14_67592237_- | SINE | Alu | Name=AluJb |
| ADediting_442816 | chr14_67592262_- | SINE | Alu | Name=AluJb |
| ADediting_442817 | chr14_67592272_- | SINE | Alu | Name=AluJb |
| ADediting_442818 | chr14_67592316_- | SINE | Alu | Name=AluJb |
| ADediting_442819 | chr14_67592318_- | SINE | Alu | Name=AluJb |
| ADediting_442820 | chr14_67592354_- | SINE | Alu | Name=AluJb |
| ADediting_442821 | chr14_67592357_- | SINE | Alu | Name=AluJb |
| ADediting_442822 | chr14_67592358_- | SINE | Alu | Name=AluJb |
| ADediting_442823 | chr14_67592364_- | SINE | Alu | Name=AluJb |
| ADediting_442824 | chr14_67592371_- | SINE | Alu | Name=AluJb |
| ADediting_442825 | chr14_67592378_- | SINE | Alu | Name=AluJb |
| ADediting_442826 | chr14_67592387_- | SINE | Alu | Name=AluJb |
| ADediting_442827 | chr14_67592416_- | SINE | Alu | Name=AluJb |
| ADediting_442828 | chr14_67592424_- | SINE | Alu | Name=AluJb |
| ADediting_442829 | chr14_67592430_- | SINE | Alu | Name=AluJb |
| ADediting_442830 | chr14_67592432_- | SINE | Alu | Name=AluJb |
| ADediting_442831 | chr14_67592823_- | SINE | Alu | Name=AluSx1 |
| ADediting_442832 | chr14_67592824_- | SINE | Alu | Name=AluSx1 |
| ADediting_442833 | chr14_67592853_- | SINE | Alu | Name=AluSx1 |
| ADediting_442834 | chr14_67592871_- | SINE | Alu | Name=AluSx1 |
| ADediting_442835 | chr14_67592882_- | SINE | Alu | Name=AluSx1 |
| ADediting_442836 | chr14_67592897_- | SINE | Alu | Name=AluSx1 |
| ADediting_442837 | chr14_67592923_- | SINE | Alu | Name=AluSx1 |
| ADediting_442838 | chr14_67592933_- | SINE | Alu | Name=AluSx1 |
| ADediting_442839 | chr14_67592965_- | SINE | Alu | Name=AluSx1 |
| ADediting_442840 | chr14_67592966_- | SINE | Alu | Name=AluSx1 |
| ADediting_442841 | chr14_67592969_- | SINE | Alu | Name=AluSx1 |
| ADediting_442842 | chr14_67593000_- | SINE | Alu | Name=AluSx1 |
| ADediting_442843 | chr14_67593020_- | SINE | Alu | Name=AluSx1 |
| ADediting_442844 | chr14_67593054_- | SINE | Alu | Name=AluSx1 |
| ADediting_442845 | chr14_67593060_- | SINE | Alu | Name=AluSx1 |
| ADediting_442846 | chr14_67593233_- | SINE | Alu | Name=AluJb |
| ADediting_442847 | chr14_67593238_- | SINE | Alu | Name=AluJb |
| ADediting_442848 | chr14_67593245_- | SINE | Alu | Name=AluJb |
| ADediting_442849 | chr14_67593268_- | SINE | Alu | Name=AluJb |
| ADediting_442850 | chr14_67593272_- | SINE | Alu | Name=AluJb |
| ADediting_442851 | chr14_67593273_- | SINE | Alu | Name=AluJb |
| ADediting_442852 | chr14_67593324_- | SINE | Alu | Name=AluJb |
| ADediting_442853 | chr14_67593363_- | SINE | Alu | Name=AluJb |
| ADediting_442854 | chr14_67593369_- | SINE | Alu | Name=AluJb |
| ADediting_442855 | chr14_67593379_- | SINE | Alu | Name=AluJb |
| ADediting_442856 | chr14_67593396_- | SINE | Alu | Name=AluJb |
| ADediting_442857 | chr14_67593408_- | SINE | Alu | Name=AluJb |
| ADediting_442858 | chr14_67593429_- | SINE | Alu | Name=AluJb |
| ADediting_442859 | chr14_67593439_- | SINE | Alu | Name=AluJb |
| ADediting_442860 | chr14_67594266_- | SINE | Alu | Name=AluJo |
| ADediting_442861 | chr14_67594318_- | SINE | Alu | Name=AluJo |
| ADediting_442862 | chr14_67594398_- | SINE | Alu | Name=AluSc |
| ADediting_442863 | chr14_67594481_- | SINE | Alu | Name=AluSc |
| ADediting_442864 | chr14_67594525_- | SINE | Alu | Name=AluSc |
| ADediting_442865 | chr14_67594564_- | SINE | Alu | Name=AluSc |
| ADediting_442866 | chr14_67594615_- | SINE | Alu | Name=AluSc |
| ADediting_442867 | chr14_67595015_- | SINE | Alu | Name=AluYc |
| ADediting_442868 | chr14_67596191_- | SINE | Alu | Name=AluSq2 |
| ADediting_442869 | chr14_67596225_- | SINE | Alu | Name=AluSq2 |
| ADediting_442870 | chr14_67596231_- | SINE | Alu | Name=AluSq2 |
| ADediting_442871 | chr14_67596244_- | SINE | Alu | Name=AluSq2 |
| ADediting_442872 | chr14_67596257_- | SINE | Alu | Name=AluSq2 |
| ADediting_442873 | chr14_67596266_- | SINE | Alu | Name=AluSq2 |
| ADediting_442874 | chr14_67596267_- | SINE | Alu | Name=AluSq2 |
| ADediting_442875 | chr14_67596340_- | SINE | Alu | Name=AluSq2 |
| ADediting_442876 | chr14_67596344_- | SINE | Alu | Name=AluSq2 |
| ADediting_442877 | chr14_67596350_- | SINE | Alu | Name=AluSq2 |
| ADediting_442878 | chr14_67596420_- | SINE | Alu | Name=AluSq2 |
| ADediting_442879 | chr14_67597215_- | SINE | Alu | Name=AluJo |
| ADediting_442880 | chr14_67597312_- | SINE | Alu | Name=AluJo |
| ADediting_442881 | chr14_67597330_- | SINE | Alu | Name=AluJo |
| ADediting_442882 | chr14_67597354_- | SINE | Alu | Name=AluJo |
| ADediting_442883 | chr14_67597366_- | SINE | Alu | Name=AluJo |
| ADediting_442884 | chr14_67597395_- | SINE | Alu | Name=AluJo |
| ADediting_442885 | chr14_67597396_- | SINE | Alu | Name=AluJo |
| ADediting_442886 | chr14_67597416_- | SINE | Alu | Name=AluJo |
| ADediting_442887 | chr14_67597418_- | SINE | Alu | Name=AluJo |
| ADediting_442888 | chr14_67597464_- | SINE | Alu | Name=AluJo |
| ADediting_442889 | chr14_67598947_- | SINE | Alu | Name=AluSz |
| ADediting_442890 | chr14_67598965_- | SINE | Alu | Name=AluSz |
| ADediting_442891 | chr14_67598996_- | SINE | Alu | Name=AluSz |
| ADediting_1537437 | chr14_67590523_- | SINE | Alu | Name=AluSz6 |
| ADediting_1537438 | chr14_67590532_- | SINE | Alu | Name=AluSz6 |
| ADediting_1537439 | chr14_67590538_- | SINE | Alu | Name=AluSz6 |
| ADediting_1537440 | chr14_67590541_- | SINE | Alu | Name=AluSz6 |
| ADediting_1537441 | chr14_67590552_- | SINE | Alu | Name=AluSz6 |
| ADediting_1537442 | chr14_67590632_- | SINE | Alu | Name=AluSz6 |
| ADediting_1537444 | chr14_67591640_- | SINE | Alu | Name=AluJb |
| ADediting_1537445 | chr14_67591664_- | SINE | Alu | Name=AluJb |
| ADediting_1537446 | chr14_67591688_- | SINE | Alu | Name=AluJb |
| ADediting_1537447 | chr14_67591699_- | SINE | Alu | Name=AluJb |
| ADediting_1537448 | chr14_67591728_- | SINE | Alu | Name=AluJb |
| ADediting_1537449 | chr14_67591736_- | SINE | Alu | Name=AluJb |
| ADediting_1537450 | chr14_67591746_- | SINE | Alu | Name=AluJb |
| ADediting_1537451 | chr14_67591765_- | SINE | Alu | Name=AluJb |
| ADediting_1537452 | chr14_67591770_- | SINE | Alu | Name=AluJb |
| ADediting_1537453 | chr14_67592213_- | SINE | Alu | Name=AluJb |
| ADediting_1537454 | chr14_67592214_- | SINE | Alu | Name=AluJb |
| ADediting_1537455 | chr14_67592252_- | SINE | Alu | Name=AluJb |
| ADediting_1537456 | chr14_67592269_- | SINE | Alu | Name=AluJb |
| ADediting_1537457 | chr14_67592308_- | SINE | Alu | Name=AluJb |
| ADediting_1537458 | chr14_67592328_- | SINE | Alu | Name=AluJb |
| ADediting_1537459 | chr14_67592353_- | SINE | Alu | Name=AluJb |
| ADediting_1537460 | chr14_67592355_- | SINE | Alu | Name=AluJb |
| ADediting_1537461 | chr14_67592393_- | SINE | Alu | Name=AluJb |
| ADediting_1537462 | chr14_67592405_- | SINE | Alu | Name=AluJb |
| ADediting_1537463 | chr14_67592821_- | SINE | Alu | Name=AluSx1 |
| ADediting_1537464 | chr14_67592858_- | SINE | Alu | Name=AluSx1 |
| ADediting_1537465 | chr14_67592954_- | SINE | Alu | Name=AluSx1 |
| ADediting_1537466 | chr14_67593059_- | SINE | Alu | Name=AluSx1 |
| ADediting_1537467 | chr14_67593298_- | SINE | Alu | Name=AluJb |
| ADediting_1537468 | chr14_67593316_- | SINE | Alu | Name=AluJb |
| ADediting_1537469 | chr14_67593333_- | SINE | Alu | Name=AluJb |
| ADediting_1537470 | chr14_67593367_- | SINE | Alu | Name=AluJb |
| ADediting_1537471 | chr14_67593391_- | SINE | Alu | Name=AluJb |
| ADediting_1537472 | chr14_67593415_- | SINE | Alu | Name=AluJb |
| ADediting_1537473 | chr14_67593422_- | SINE | Alu | Name=AluJb |
| ADediting_1537474 | chr14_67593434_- | SINE | Alu | Name=AluJb |
| ADediting_1537475 | chr14_67593453_- | SINE | Alu | Name=AluJb |
| ADediting_1620008 | chr14_67597350_- | SINE | Alu | Name=AluJo |
Top |
RNA A-to-I editing events in the alternative splicing sites for PIGH |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| ES | ADediting_442818 | chr14_67592316_- | 67592309:67592317 | 5ss | 2e | CAGGTGTGC | 6.46 | CGGGTGTGC | 4.15 |
| ES | ADediting_442818 | chr14_67592316_- | 67592309:67592317 | 5ss | 2e | CAGGTGTGC | 6.46 | CGGGTGTGC | 4.15 |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for PIGH |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for PIGH |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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Top |
The effects of the RNA editing to the miRNA binding sites for PIGH |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1537453 | chr14_67592213_- | ENSG00000100564.9 | ENST00000559581.5 | PIGH-209 | hsa-miR-146a-5p | chr14 | 67592208 | 67592214 | 7mer-m8 | 67592207 | 67592231 | 149 | -17.16 |
| ADediting_1537453 | chr14_67592213_- | ENSG00000100564.9 | ENST00000559581.5 | PIGH-209 | hsa-miR-146b-5p | chr14 | 67592208 | 67592214 | 7mer-m8 | 67592207 | 67592230 | 147 | -17.07 |
| ADediting_1537453 | chr14_67592213_- | ENSG00000100564.9 | ENST00000559581.5 | PIGH-209 | hsa-miR-7153-5p | chr14 | 67592208 | 67592214 | 7mer-m8 | 67592207 | 67592229 | 145 | -17.66 |
| ADediting_442811 | chr14_67592175_- | ENSG00000100564.9 | ENST00000559581.5 | PIGH-209 | hsa-miR-6514-3p | chr14 | 67592172 | 67592178 | 7mer-m8 | 67592171 | 67592191 | 155 | -17.54 |
| ADediting_442812 | chr14_67592178_- | ENSG00000100564.9 | ENST00000559581.5 | PIGH-209 | hsa-miR-4327 | chr14 | 67592172 | 67592179 | 8mer-1a | 67592172 | 67592190 | 140 | -11.95 |
| ADediting_442813 | chr14_67592217_- | ENSG00000100564.9 | ENST00000559581.5 | PIGH-209 | hsa-miR-12113 | chr14 | 67592217 | 67592223 | 7mer-m8 | 67592216 | 67592240 | 146 | -21.75 |
| ADediting_442813 | chr14_67592217_- | ENSG00000100564.9 | ENST00000559581.5 | PIGH-209 | hsa-miR-4539 | chr14 | 67592217 | 67592223 | 7mer-m8 | 67592216 | 67592235 | 147 | -15.09 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1537453 | chr14_67592213_- | ENSG00000100564.9 | ENST00000559581.5 | PIGH-209 | hsa-miR-219b-3p | chr14 | 67592210 | 67592216 | 7mer-m8 | 67592209 | 67592227 | 155 | -18.52 |
| ADediting_1537453 | chr14_67592213_- | ENSG00000100564.9 | ENST00000559581.5 | PIGH-209 | hsa-miR-302f | chr14 | 67592211 | 67592217 | 7mer-m8 | 67592210 | 67592226 | 145 | -6.24 |
| ADediting_1537454 | chr14_67592214_- | ENSG00000100564.9 | ENST00000559581.5 | PIGH-209 | hsa-miR-219b-3p | chr14 | 67592210 | 67592216 | 7mer-m8 | 67592209 | 67592227 | 155 | -18.52 |
| ADediting_1537454 | chr14_67592214_- | ENSG00000100564.9 | ENST00000559581.5 | PIGH-209 | hsa-miR-302f | chr14 | 67592211 | 67592217 | 7mer-m8 | 67592210 | 67592226 | 145 | -6.24 |
| ADediting_442814 | chr14_67592223_- | ENSG00000100564.9 | ENST00000559581.5 | PIGH-209 | hsa-miR-510-5p | chr14 | 67592221 | 67592227 | 7mer-m8 | 67592220 | 67592241 | 150 | -19.76 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1631458 | chr19_40282624_- | ENSG00000100564.9 | ENST00000216452.9 | PIGH-201 | hsa-miR-641 | chr14 | 67589626 | 67589633 | 8mer-1a | 67589626 | 67589649 | 140 | -12.03 |
| ADediting_286380 | chr11_79422188_- | ENSG00000100564.9 | ENST00000216452.9 | PIGH-201 | hsa-miR-5579-3p | chr14 | 67590025 | 67590031 | 7mer-m8 | 67590024 | 67590044 | 156 | -17.69 |
| ADediting_286380 | chr11_79422188_- | ENSG00000100564.9 | ENST00000558493.1 | PIGH-204 | hsa-miR-5579-3p | chr14 | 67590025 | 67590031 | 7mer-m8 | 67590024 | 67590044 | 156 | -17.69 |
| ADediting_286380 | chr11_79422188_- | ENSG00000100564.9 | ENST00000558987.5 | PIGH-205 | hsa-miR-5579-3p | chr14 | 67590025 | 67590031 | 7mer-m8 | 67590024 | 67590044 | 156 | -17.69 |
| ADediting_286380 | chr11_79422188_- | ENSG00000100564.9 | ENST00000560722.5 | PIGH-210 | hsa-miR-5579-3p | chr14 | 67590025 | 67590031 | 7mer-m8 | 67590024 | 67590044 | 156 | -17.69 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000100564.9 | ENST00000559581.5 | PIGH-209 | hsa-miR-4775 | chr14 | 67591883 | 67591889 | 7mer-m8 | 67591882 | 67591903 | 140 | -6.92 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000100564.9 | ENST00000559581.5 | PIGH-209 | hsa-miR-5585-3p | chr14 | 67592090 | 67592096 | 7mer-m8 | 67592089 | 67592108 | 144 | -15.55 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1391023 | chr8_140732605_- | ENSG00000100564.9 | ENST00000559581.5 | PIGH-209 | hsa-miR-151a-3p | chr14 | 67592067 | 67592073 | 7mer-m8 | 67592066 | 67592087 | 146 | -12.91 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000100564.9 | ENST00000216452.9 | PIGH-201 | hsa-miR-641 | chr14 | 67589716 | 67589722 | 7mer-m8 | 67589715 | 67589739 | 153 | -16.6 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000100564.9 | ENST00000558987.5 | PIGH-205 | hsa-miR-641 | chr14 | 67589716 | 67589722 | 7mer-m8 | 67589715 | 67589739 | 153 | -16.6 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000100564.9 | ENST00000216452.9 | PIGH-201 | hsa-miR-641 | chr14 | 67589716 | 67589722 | 7mer-m8 | 67589715 | 67589739 | 153 | -16.6 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000100564.9 | ENST00000558987.5 | PIGH-205 | hsa-miR-641 | chr14 | 67589716 | 67589722 | 7mer-m8 | 67589715 | 67589739 | 153 | -16.6 |
| Differentially expressed gene-miRNA network |
Top |
The effects of the RNA editing to the stability of the RNA structures for PIGH |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000558987.5 | protein_coding |  |  |
| ENST00000559581.5 | protein_coding |  |  |
| ENST00000559415.1 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_442818 | ENST00000558987.5 | chr14_67592316_- | 381 | -274.60 | -268.40 | -295.20 |
| ADediting_442819 | ENST00000558987.5 | chr14_67592318_- | 379 | -269.20 | -268.40 | -295.20 |
| ADediting_1537458 | ENST00000558987.5 | chr14_67592328_- | 369 | -271.30 | -268.40 | -295.20 |
| ADediting_1537459 | ENST00000558987.5 | chr14_67592353_- | 344 | -271.50 | -268.40 | -295.20 |
| ADediting_442820 | ENST00000558987.5 | chr14_67592354_- | 343 | -269.30 | -268.40 | -295.20 |
| ADediting_1537460 | ENST00000558987.5 | chr14_67592355_- | 342 | -272.40 | -268.40 | -295.20 |
| ADediting_442821 | ENST00000558987.5 | chr14_67592357_- | 340 | -272.00 | -268.40 | -295.20 |
| ADediting_442822 | ENST00000558987.5 | chr14_67592358_- | 339 | -270.80 | -268.40 | -295.20 |
| ADediting_442823 | ENST00000558987.5 | chr14_67592364_- | 333 | -268.40 | -268.40 | -295.20 |
| ADediting_442824 | ENST00000558987.5 | chr14_67592371_- | 326 | -269.30 | -268.40 | -295.20 |
| ADediting_442825 | ENST00000558987.5 | chr14_67592378_- | 319 | -267.70 | -268.40 | -295.20 |
| ADediting_442826 | ENST00000558987.5 | chr14_67592387_- | 310 | -268.00 | -268.40 | -295.20 |
| ADediting_1537461 | ENST00000558987.5 | chr14_67592393_- | 304 | -268.40 | -268.40 | -295.20 |
| ADediting_1537462 | ENST00000558987.5 | chr14_67592405_- | 292 | -268.30 | -268.40 | -295.20 |
| ADediting_442827 | ENST00000558987.5 | chr14_67592416_- | 281 | -268.70 | -268.40 | -295.20 |
| ADediting_442828 | ENST00000558987.5 | chr14_67592424_- | 273 | -268.70 | -268.40 | -295.20 |
| ADediting_442829 | ENST00000558987.5 | chr14_67592430_- | 267 | -269.90 | -268.40 | -295.20 |
| ADediting_442830 | ENST00000558987.5 | chr14_67592432_- | 265 | -269.90 | -268.40 | -295.20 |
| ADediting_442811 | ENST00000559581.5 | chr14_67592175_- | 683 | -344.20 | -343.10 | -374.70 |
| ADediting_442812 | ENST00000559581.5 | chr14_67592178_- | 680 | -343.10 | -343.10 | -374.70 |
| ADediting_1537453 | ENST00000559581.5 | chr14_67592213_- | 645 | -345.90 | -343.10 | -374.70 |
| ADediting_1537454 | ENST00000559581.5 | chr14_67592214_- | 644 | -344.00 | -343.10 | -374.70 |
| ADediting_442813 | ENST00000559581.5 | chr14_67592217_- | 641 | -342.80 | -343.10 | -374.70 |
| ADediting_442814 | ENST00000559581.5 | chr14_67592223_- | 635 | -343.10 | -343.10 | -374.70 |
| ADediting_442815 | ENST00000559581.5 | chr14_67592237_- | 621 | -342.40 | -343.10 | -374.70 |
| ADediting_1537455 | ENST00000559581.5 | chr14_67592252_- | 606 | -344.90 | -343.10 | -374.70 |
| ADediting_442816 | ENST00000559581.5 | chr14_67592262_- | 596 | -342.20 | -343.10 | -374.70 |
| ADediting_1537456 | ENST00000559581.5 | chr14_67592269_- | 589 | -342.80 | -343.10 | -374.70 |
| ADediting_442817 | ENST00000559581.5 | chr14_67592272_- | 586 | -343.10 | -343.10 | -374.70 |
| ADediting_1537457 | ENST00000559581.5 | chr14_67592308_- | 550 | -344.10 | -343.10 | -374.70 |
| ADediting_442818 | ENST00000559581.5 | chr14_67592316_- | 542 | -343.00 | -343.10 | -374.70 |
| ADediting_442819 | ENST00000559581.5 | chr14_67592318_- | 540 | -343.10 | -343.10 | -374.70 |
| ADediting_1537458 | ENST00000559581.5 | chr14_67592328_- | 530 | -346.00 | -343.10 | -374.70 |
| ADediting_1537459 | ENST00000559581.5 | chr14_67592353_- | 505 | -343.70 | -343.10 | -374.70 |
| ADediting_442820 | ENST00000559581.5 | chr14_67592354_- | 504 | -345.00 | -343.10 | -374.70 |
| ADediting_1537460 | ENST00000559581.5 | chr14_67592355_- | 503 | -347.50 | -343.10 | -374.70 |
| ADediting_442821 | ENST00000559581.5 | chr14_67592357_- | 501 | -349.70 | -343.10 | -374.70 |
| ADediting_442822 | ENST00000559581.5 | chr14_67592358_- | 500 | -346.70 | -343.10 | -374.70 |
| ADediting_442823 | ENST00000559581.5 | chr14_67592364_- | 494 | -343.10 | -343.10 | -374.70 |
| ADediting_442824 | ENST00000559581.5 | chr14_67592371_- | 487 | -343.50 | -343.10 | -374.70 |
| ADediting_442825 | ENST00000559581.5 | chr14_67592378_- | 480 | -342.40 | -343.10 | -374.70 |
| ADediting_442826 | ENST00000559581.5 | chr14_67592387_- | 471 | -342.70 | -343.10 | -374.70 |
| ADediting_1537461 | ENST00000559581.5 | chr14_67592393_- | 465 | -343.10 | -343.10 | -374.70 |
| ADediting_1537462 | ENST00000559581.5 | chr14_67592405_- | 453 | -345.70 | -343.10 | -374.70 |
| ADediting_442827 | ENST00000559581.5 | chr14_67592416_- | 442 | -343.00 | -343.10 | -374.70 |
| ADediting_442828 | ENST00000559581.5 | chr14_67592424_- | 434 | -343.40 | -343.10 | -374.70 |
| ADediting_442829 | ENST00000559581.5 | chr14_67592430_- | 428 | -342.90 | -343.10 | -374.70 |
| ADediting_442830 | ENST00000559581.5 | chr14_67592432_- | 426 | -342.90 | -343.10 | -374.70 |
| ADediting_1537462 | ENST00000559415.1 | chr14_67592405_- | 475 | -182.60 | -182.60 | -193.20 |
| ADediting_442827 | ENST00000559415.1 | chr14_67592416_- | 464 | -184.90 | -182.60 | -193.20 |
| ADediting_442828 | ENST00000559415.1 | chr14_67592424_- | 456 | -182.90 | -182.60 | -193.20 |
| ADediting_442829 | ENST00000559415.1 | chr14_67592430_- | 450 | -181.80 | -182.60 | -193.20 |
| ADediting_442830 | ENST00000559415.1 | chr14_67592432_- | 448 | -182.30 | -182.60 | -193.20 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for PIGH |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_1537450 | chr14_67591746_- | 1.9647135868478e-05 | 0.340904009971396 | 1.92083395853944e-07 | 0.409747286288396 | 0.738366682800491 | 0.0274972480190895 |
| DLPFC | ADediting_442802 | chr14_67591624_- | 2.46509514405781e-05 | 0.237097864602544 | 0.0059449596751235 | 0.155908380877204 | 3.96848550577911e-08 | 0.305675704150886 |
| CER | ADediting_442802 | chr14_67591624_- | 3.13850007343677e-09 | 0.460147114038691 | 1.63674550820317e-07 | 0.411869649213747 | 0.482653029950714 | 0.0577567682799047 |
| DLPFC | ADediting_442804 | chr14_67591652_- | 0.0140902673538952 | 0.139314211721465 | 0.513356418319826 | 0.0372607731622978 | 2.67238736400224e-11 | 0.366683406874942 |
| CER | ADediting_442804 | chr14_67591652_- | 7.37941290891727e-11 | 0.499892891451971 | 3.12753217260244e-08 | 0.432999753742264 | 0.882642522757874 | 0.0121543697457259 |
| CER | ADediting_442806 | chr14_67591696_- | 3.03807103335266e-07 | 0.403585218157326 | 1.10676696048824e-05 | 0.350355047114854 | 0.866233195314774 | -0.0138688360483398 |
| CER | ADediting_442810 | chr14_67591808_- | 2.86530327737043e-05 | 0.334519088344686 | 4.52147335494662e-05 | 0.32660710158164 | 0.595289443503765 | -0.0437161709201147 |
| CER | ADediting_442815 | chr14_67592237_- | 8.6520101174507e-06 | 0.354318668877712 | 1.68403222283948e-07 | 0.411493040424554 | 0.36138928468615 | 0.0750459973356876 |
| CER | ADediting_442817 | chr14_67592272_- | 1.30739513800591e-07 | 0.414824448480397 | 1.47676355403144e-06 | 0.381324078842514 | 0.371180945525027 | 0.0735325297411529 |
| CER | ADediting_442818 | chr14_67592316_- | 5.64541766522846e-05 | 0.322676187415556 | 6.54976955987202e-05 | 0.320014726724828 | 0.680695332068051 | 0.0338737395506276 |
| CER | ADediting_442819 | chr14_67592318_- | 0.000509404315530653 | 0.280424536489753 | 5.25867521488857e-05 | 0.32393860134167 | 0.187296976314965 | 0.108253584108305 |
| CER | ADediting_442821 | chr14_67592357_- | 0.00258256161688831 | 0.244354031630837 | 1.25980545728942e-05 | 0.348248672399682 | 0.315160398754334 | 0.0825637925843668 |
| CER | ADediting_442822 | chr14_67592358_- | 0.00284428668380208 | 0.242040746801008 | 9.17640864518194e-05 | 0.313880560136169 | 0.708370960446335 | 0.0307909697840446 |
| DLPFC | ADediting_442823 | chr14_67592364_- | 3.14822178702543e-11 | 0.365449548224875 | 5.34110451646359e-06 | 0.255213173145241 | 0.000170755953865673 | 0.211909933008451 |
| CER | ADediting_442823 | chr14_67592364_- | 3.2796756030084e-06 | 0.369437189960173 | 7.07013750809275e-07 | 0.391896710851724 | 0.186261443790832 | 0.108506763474533 |
| CER | ADediting_442824 | chr14_67592371_- | 9.71620791118007e-06 | 0.352458015222785 | 1.38342191269055e-07 | 0.41408374731575 | 0.002673990368462 | 0.243522770099014 |
| DLPFC | ADediting_442830 | chr14_67592432_- | 4.47520541946765e-09 | 0.325350545910319 | 0.000821885578734914 | 0.189048811141195 | 0.000416572431392218 | 0.199245327983324 |
| CER | ADediting_442830 | chr14_67592432_- | 1.58137792448149e-05 | 0.344514350671644 | 1.47938211812685e-05 | 0.345614459775663 | 0.71633146113529 | 0.0299123029172962 |
| DLPFC | ADediting_442845 | chr14_67593060_- | 0.00109283703729912 | 0.184615135927128 | 0.059080050204503 | 0.107332018851913 | 1.7702727198623e-14 | 0.41709674641059 |
| DLPFC | ADediting_442846 | chr14_67593233_- | 1.85260590943057e-05 | 0.240588913210763 | 0.0196271352685957 | 0.132478773743366 | 1.68575364808101e-09 | 0.333714111525453 |
| DLPFC | ADediting_442850 | chr14_67593272_- | 0.000622632182638706 | 0.193276750724884 | 0.375649264055842 | 0.0504899401971776 | 8.98787464691998e-18 | 0.46170243405902 |
| CER | ADediting_442850 | chr14_67593272_- | 3.5872100698836e-05 | 0.33064888883463 | 0.00431138075792543 | 0.231819159848431 | 0.0469018854364081 | -0.162532117366594 |
| DLPFC | ADediting_442851 | chr14_67593273_- | 0.00054561568572511 | 0.195256931991433 | 0.391625914980099 | 0.0488239404339973 | 2.0294052685559e-16 | 0.444158732517331 |
| CER | ADediting_442851 | chr14_67593273_- | 0.000156539807624454 | 0.303883012396529 | 0.00262547814276814 | 0.243960577976801 | 0.0969723494775133 | -0.136022235085557 |
| CER | ADediting_442854 | chr14_67593369_- | 3.92573894581293e-06 | 0.36669211268786 | 0.0128958531675631 | 0.202617171655891 | 0.449538908228802 | -0.0622026942797475 |
| CER | ADediting_442856 | chr14_67593396_- | 3.29498119549502e-05 | 0.332118575770692 | 0.0475089098434096 | 0.162092268775859 | 0.408996318476465 | -0.0679051504925296 |
| DLPFC | ADediting_442862 | chr14_67594398_- | 0.25850627564227 | 0.0643690981473688 | 0.334077687308522 | -0.0550420666752354 | 5.11557128935332e-19 | 0.476989489688147 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 3.31894447275704e-65 | 0.782015957540122 | 9.55701575735139e-41 | 0.663792543278618 | 9.31199380256001e-15 | 0.421139603539576 |
| AC | 1.79978595882933e-57 | 0.802181249878026 | 6.07942995389834e-36 | 0.68479706092366 | 1.67770606104407e-20 | 0.542134938938695 |
| PCC | 4.50297303649831e-24 | 0.647411454194894 | 1.28842978985603e-26 | 0.673663298623157 | 0.023805416440586 | 0.163517346893012 |
| CER | 1.24062704671084e-29 | 0.761227720146283 | 2.39916664632494e-16 | 0.605043812842391 | 0.179653900933416 | 0.110147020910097 |
| TCX | 2.82113038901643e-46 | 0.865462725985899 | 5.02038205008898e-15 | 0.582928178939357 | 0.00355826786615569 | 0.236589591898074 |
| FP | 5.72280832403949e-11 | 0.465732522819396 | 6.34952261084892e-21 | 0.628094587735428 | 0.782578069127429 | 0.0208286458665615 |
| IFG | 9.45945030662384e-05 | 0.701109593017373 | 0.000261481784643065 | 0.668234902382543 | 0.784841578783864 | -0.0575017549719734 |
| PG | 3.77203818960518e-32 | 0.729303343277141 | 2.59746206935224e-28 | 0.696376534838771 | 0.590122053426448 | -0.0397487505535372 |
| STG | 4.02270314748483e-14 | 0.709886393172771 | 1.99509452402605e-14 | 0.715722084202081 | 0.855915941432199 | 0.0201108394341339 |
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Relation with AD stages for PIGH |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
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RelatedDrugs for PIGH |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PIGH |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| PIGH | C3714756 | Intellectual Disability | 1 | GENOMICS_ENGLAND |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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