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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for PFKP |
 Gene summary |
| Gene information | Gene symbol | PFKP | Gene ID | 5214 |
| Gene name | phosphofructokinase, platelet | |
| Synonyms | ATP-PFK|PFK-C|PFK-P|PFKF | |
| Cytomap | 10p15.2 | |
| Type of gene | protein-coding | |
| Description | ATP-dependent 6-phosphofructokinase, platelet type6-phosphofructokinase type C6-phosphofructokinase, platelet typephosphofructo-1-kinase isozyme Cphosphofructokinase 1phosphohexokinase | |
| Modification date | 20200313 | |
| UniProtAcc | Q01813, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for PFKP |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_192254(3069628, +), ADediting_192255(3069633, +), ADediting_192256(3069654, +), ADediting_192257(3070781, +), ADediting_192258(3070833, +), ADediting_192259(3070850, +), ADediting_192260(3070851, +), ADediting_192261(3070931, +), ADediting_192262(3070948, +), ADediting_192263(3071012, +), ADediting_192264(3071013, +), ADediting_192265(3071025, +), ADediting_192266(3071034, +), ADediting_192267(3073917, +), ADediting_192268(3073932, +), ADediting_192269(3073938, +), ADediting_192270(3073963, +), ADediting_192271(3073964, +), ADediting_192272(3074021, +), ADediting_192273(3074037, +), ADediting_192274(3074100, +), ADediting_192275(3075647, +), ADediting_192276(3075648, +), ADediting_192277(3075653, +), ADediting_192278(3075661, +), ADediting_192279(3075670, +), ADediting_192280(3075717, +), ADediting_192281(3075724, +), ADediting_192282(3075725, +), ADediting_192283(3075758, +), ADediting_192284(3075778, +), ADediting_192285(3075782, +), ADediting_192286(3075784, +), ADediting_192287(3075807, +), ADediting_192288(3075825, +), ADediting_192289(3075830, +), ADediting_192290(3075875, +), ADediting_192291(3075940, +), ADediting_192292(3077326, +), ADediting_192293(3077342, +), ADediting_192294(3077362, +), ADediting_192295(3077379, +), ADediting_192296(3079258, +), ADediting_192297(3080255, +), ADediting_192298(3080262, +), ADediting_192299(3080263, +), ADediting_192300(3080271, +), ADediting_192301(3082776, +), ADediting_192302(3082780, +), ADediting_192303(3082813, +), ADediting_192329(3091653, +), ADediting_192333(3093737, +), ADediting_192369(3098421, +), ADediting_192370(3098554, +), ADediting_192412(3102064, +), ADediting_192413(3102074, +), ADediting_192414(3102130, +), ADediting_192415(3102136, +), ADediting_192416(3102140, +), ADediting_192417(3102450, +), ADediting_192418(3102513, +), ADediting_192419(3102514, +), ADediting_192420(3102517, +), ADediting_192421(3102518, +), ADediting_192422(3102540, +), ADediting_192423(3102543, +), ADediting_192424(3102553, +), ADediting_192425(3102555, +), ADediting_192426(3102559, +), ADediting_192427(3102632, +), ADediting_192428(3102641, +), ADediting_192429(3102675, +), ADediting_192432(3120729, +), ADediting_192433(3120734, +), ADediting_192434(3120739, +), ADediting_192435(3120746, +), ADediting_192436(3121915, +), ADediting_192437(3121934, +), ADediting_192438(3125611, +), ADediting_192439(3125983, +), ADediting_192440(3125985, +), ADediting_192441(3125988, +), ADediting_192442(3125990, +), ADediting_192443(3125991, +), ADediting_192444(3126006, +), ADediting_192445(3126014, +), ADediting_192446(3126485, +), ADediting_192447(3126487, +), ADediting_192448(3126502, +), ADediting_192449(3126514, +), ADediting_192516(3136143, +), ADediting_1523291(3070870, +), ADediting_1523292(3070957, +), ADediting_1523294(3133524, +), ADediting_1605412(3133510, +), ADediting_1605413(3133511, +), |
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RNA editing positional annotations for PFKP using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_192254 | chr10_3069628_+ | intronic |
| ADediting_192255 | chr10_3069633_+ | intronic |
| ADediting_192256 | chr10_3069654_+ | intronic |
| ADediting_192257 | chr10_3070781_+ | intronic |
| ADediting_192258 | chr10_3070833_+ | intronic |
| ADediting_192259 | chr10_3070850_+ | intronic |
| ADediting_192260 | chr10_3070851_+ | intronic |
| ADediting_192261 | chr10_3070931_+ | intronic |
| ADediting_192262 | chr10_3070948_+ | intronic |
| ADediting_192263 | chr10_3071012_+ | intronic |
| ADediting_192264 | chr10_3071013_+ | intronic |
| ADediting_192265 | chr10_3071025_+ | intronic |
| ADediting_192266 | chr10_3071034_+ | intronic |
| ADediting_192267 | chr10_3073917_+ | intronic |
| ADediting_192268 | chr10_3073932_+ | intronic |
| ADediting_192269 | chr10_3073938_+ | intronic |
| ADediting_192270 | chr10_3073963_+ | intronic |
| ADediting_192271 | chr10_3073964_+ | intronic |
| ADediting_192272 | chr10_3074021_+ | intronic |
| ADediting_192273 | chr10_3074037_+ | intronic |
| ADediting_192274 | chr10_3074100_+ | intronic |
| ADediting_192275 | chr10_3075647_+ | intronic |
| ADediting_192276 | chr10_3075648_+ | intronic |
| ADediting_192277 | chr10_3075653_+ | intronic |
| ADediting_192278 | chr10_3075661_+ | intronic |
| ADediting_192279 | chr10_3075670_+ | intronic |
| ADediting_192280 | chr10_3075717_+ | intronic |
| ADediting_192281 | chr10_3075724_+ | intronic |
| ADediting_192282 | chr10_3075725_+ | intronic |
| ADediting_192283 | chr10_3075758_+ | intronic |
| ADediting_192284 | chr10_3075778_+ | intronic |
| ADediting_192285 | chr10_3075782_+ | intronic |
| ADediting_192286 | chr10_3075784_+ | intronic |
| ADediting_192287 | chr10_3075807_+ | intronic |
| ADediting_192288 | chr10_3075825_+ | intronic |
| ADediting_192289 | chr10_3075830_+ | intronic |
| ADediting_192290 | chr10_3075875_+ | intronic |
| ADediting_192291 | chr10_3075940_+ | intronic |
| ADediting_192292 | chr10_3077326_+ | intronic |
| ADediting_192293 | chr10_3077342_+ | intronic |
| ADediting_192294 | chr10_3077362_+ | intronic |
| ADediting_192295 | chr10_3077379_+ | intronic |
| ADediting_192296 | chr10_3079258_+ | intronic |
| ADediting_192297 | chr10_3080255_+ | intronic |
| ADediting_192298 | chr10_3080262_+ | intronic |
| ADediting_192299 | chr10_3080263_+ | intronic |
| ADediting_192300 | chr10_3080271_+ | intronic |
| ADediting_192301 | chr10_3082776_+ | intronic |
| ADediting_192302 | chr10_3082780_+ | intronic |
| ADediting_192303 | chr10_3082813_+ | intronic |
| ADediting_192329 | chr10_3091653_+ | intronic |
| ADediting_192333 | chr10_3093737_+ | intronic |
| ADediting_192369 | chr10_3098421_+ | intronic |
| ADediting_192370 | chr10_3098554_+ | intronic |
| ADediting_192412 | chr10_3102064_+ | intronic |
| ADediting_192413 | chr10_3102074_+ | intronic |
| ADediting_192414 | chr10_3102130_+ | intronic |
| ADediting_192415 | chr10_3102136_+ | intronic |
| ADediting_192416 | chr10_3102140_+ | intronic |
| ADediting_192417 | chr10_3102450_+ | intronic |
| ADediting_192418 | chr10_3102513_+ | intronic |
| ADediting_192419 | chr10_3102514_+ | intronic |
| ADediting_192420 | chr10_3102517_+ | intronic |
| ADediting_192421 | chr10_3102518_+ | intronic |
| ADediting_192422 | chr10_3102540_+ | intronic |
| ADediting_192423 | chr10_3102543_+ | intronic |
| ADediting_192424 | chr10_3102553_+ | intronic |
| ADediting_192425 | chr10_3102555_+ | intronic |
| ADediting_192426 | chr10_3102559_+ | intronic |
| ADediting_192427 | chr10_3102632_+ | intronic |
| ADediting_192428 | chr10_3102641_+ | intronic |
| ADediting_192429 | chr10_3102675_+ | intronic |
| ADediting_192432 | chr10_3120729_+ | intronic |
| ADediting_192433 | chr10_3120734_+ | intronic |
| ADediting_192434 | chr10_3120739_+ | intronic |
| ADediting_192435 | chr10_3120746_+ | intronic |
| ADediting_192436 | chr10_3121915_+ | intronic |
| ADediting_192437 | chr10_3121934_+ | intronic |
| ADediting_192438 | chr10_3125611_+ | intronic |
| ADediting_192439 | chr10_3125983_+ | intronic |
| ADediting_192440 | chr10_3125985_+ | intronic |
| ADediting_192441 | chr10_3125988_+ | intronic |
| ADediting_192442 | chr10_3125990_+ | intronic |
| ADediting_192443 | chr10_3125991_+ | intronic |
| ADediting_192444 | chr10_3126006_+ | intronic |
| ADediting_192445 | chr10_3126014_+ | intronic |
| ADediting_192446 | chr10_3126485_+ | intronic |
| ADediting_192447 | chr10_3126487_+ | intronic |
| ADediting_192448 | chr10_3126502_+ | intronic |
| ADediting_192449 | chr10_3126514_+ | intronic |
| ADediting_192516 | chr10_3136143_+ | ncRNA_intronic |
| ADediting_1523291 | chr10_3070870_+ | intronic |
| ADediting_1523292 | chr10_3070957_+ | intronic |
| ADediting_1523294 | chr10_3133524_+ | intronic |
| ADediting_1605412 | chr10_3133510_+ | intronic |
| ADediting_1605413 | chr10_3133511_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_192254 | chr10_3069628_+ | SINE | Alu | Name=FLAM_C |
| ADediting_192255 | chr10_3069633_+ | SINE | Alu | Name=FLAM_C |
| ADediting_192256 | chr10_3069654_+ | SINE | Alu | Name=FLAM_C |
| ADediting_192257 | chr10_3070781_+ | SINE | Alu | Name=AluJr |
| ADediting_192258 | chr10_3070833_+ | SINE | Alu | Name=AluJr |
| ADediting_192259 | chr10_3070850_+ | SINE | Alu | Name=AluJr |
| ADediting_192260 | chr10_3070851_+ | SINE | Alu | Name=AluJr |
| ADediting_192261 | chr10_3070931_+ | SINE | Alu | Name=AluJr |
| ADediting_192262 | chr10_3070948_+ | SINE | Alu | Name=AluJr |
| ADediting_192263 | chr10_3071012_+ | SINE | Alu | Name=AluJr |
| ADediting_192264 | chr10_3071013_+ | SINE | Alu | Name=AluJr |
| ADediting_192265 | chr10_3071025_+ | SINE | Alu | Name=AluJr |
| ADediting_192266 | chr10_3071034_+ | SINE | Alu | Name=AluJr |
| ADediting_192267 | chr10_3073917_+ | SINE | Alu | Name=AluSz |
| ADediting_192268 | chr10_3073932_+ | SINE | Alu | Name=AluSz |
| ADediting_192269 | chr10_3073938_+ | SINE | Alu | Name=AluSz |
| ADediting_192270 | chr10_3073963_+ | SINE | Alu | Name=AluSz |
| ADediting_192271 | chr10_3073964_+ | SINE | Alu | Name=AluSz |
| ADediting_192272 | chr10_3074021_+ | SINE | Alu | Name=AluSz |
| ADediting_192273 | chr10_3074037_+ | SINE | Alu | Name=AluSz |
| ADediting_192274 | chr10_3074100_+ | SINE | Alu | Name=AluSz |
| ADediting_192275 | chr10_3075647_+ | SINE | Alu | Name=AluJo |
| ADediting_192276 | chr10_3075648_+ | SINE | Alu | Name=AluJo |
| ADediting_192277 | chr10_3075653_+ | SINE | Alu | Name=AluJo |
| ADediting_192278 | chr10_3075661_+ | SINE | Alu | Name=AluJo |
| ADediting_192279 | chr10_3075670_+ | SINE | Alu | Name=AluJo |
| ADediting_192280 | chr10_3075717_+ | SINE | Alu | Name=AluJo |
| ADediting_192281 | chr10_3075724_+ | SINE | Alu | Name=AluJo |
| ADediting_192282 | chr10_3075725_+ | SINE | Alu | Name=AluJo |
| ADediting_192283 | chr10_3075758_+ | SINE | Alu | Name=AluJo |
| ADediting_192284 | chr10_3075778_+ | SINE | Alu | Name=AluJo |
| ADediting_192285 | chr10_3075782_+ | SINE | Alu | Name=AluJo |
| ADediting_192286 | chr10_3075784_+ | SINE | Alu | Name=AluJo |
| ADediting_192287 | chr10_3075807_+ | SINE | Alu | Name=AluJo |
| ADediting_192288 | chr10_3075825_+ | SINE | Alu | Name=AluJo |
| ADediting_192289 | chr10_3075830_+ | SINE | Alu | Name=AluJo |
| ADediting_192290 | chr10_3075875_+ | SINE | Alu | Name=AluJo |
| ADediting_192291 | chr10_3075940_+ | SINE | Alu | Name=AluYb8 |
| ADediting_192292 | chr10_3077326_+ | SINE | Alu | Name=AluSc8 |
| ADediting_192293 | chr10_3077342_+ | SINE | Alu | Name=AluSc8 |
| ADediting_192294 | chr10_3077362_+ | SINE | Alu | Name=AluSc8 |
| ADediting_192295 | chr10_3077379_+ | SINE | Alu | Name=AluSc8 |
| ADediting_192296 | chr10_3079258_+ | SINE | Alu | Name=AluY |
| ADediting_192297 | chr10_3080255_+ | SINE | Alu | Name=AluYm1 |
| ADediting_192298 | chr10_3080262_+ | SINE | Alu | Name=AluYm1 |
| ADediting_192299 | chr10_3080263_+ | SINE | Alu | Name=AluYm1 |
| ADediting_192300 | chr10_3080271_+ | SINE | Alu | Name=AluYm1 |
| ADediting_192301 | chr10_3082776_+ | SINE | Alu | Name=AluSx1 |
| ADediting_192302 | chr10_3082780_+ | SINE | Alu | Name=AluSx1 |
| ADediting_192303 | chr10_3082813_+ | SINE | Alu | Name=AluSx1 |
| ADediting_192329 | chr10_3091653_+ | SINE | Alu | Name=AluSz |
| ADediting_192333 | chr10_3093737_+ | SINE | Alu | Name=AluY |
| ADediting_192369 | chr10_3098421_+ | SINE | Alu | Name=AluSx1 |
| ADediting_192370 | chr10_3098554_+ | SINE | Alu | Name=AluSx1 |
| ADediting_192412 | chr10_3102064_+ | SINE | Alu | Name=AluYa5 |
| ADediting_192413 | chr10_3102074_+ | SINE | Alu | Name=AluYa5 |
| ADediting_192414 | chr10_3102130_+ | SINE | Alu | Name=AluYa5 |
| ADediting_192415 | chr10_3102136_+ | SINE | Alu | Name=AluYa5 |
| ADediting_192416 | chr10_3102140_+ | SINE | Alu | Name=AluYa5 |
| ADediting_192417 | chr10_3102450_+ | SINE | Alu | Name=AluSx |
| ADediting_192418 | chr10_3102513_+ | SINE | Alu | Name=AluSx |
| ADediting_192419 | chr10_3102514_+ | SINE | Alu | Name=AluSx |
| ADediting_192420 | chr10_3102517_+ | SINE | Alu | Name=AluSx |
| ADediting_192421 | chr10_3102518_+ | SINE | Alu | Name=AluSx |
| ADediting_192422 | chr10_3102540_+ | SINE | Alu | Name=AluSx |
| ADediting_192423 | chr10_3102543_+ | SINE | Alu | Name=AluSx |
| ADediting_192424 | chr10_3102553_+ | SINE | Alu | Name=AluSx |
| ADediting_192425 | chr10_3102555_+ | SINE | Alu | Name=AluSx |
| ADediting_192426 | chr10_3102559_+ | SINE | Alu | Name=AluSx |
| ADediting_192427 | chr10_3102632_+ | SINE | Alu | Name=AluSx |
| ADediting_192428 | chr10_3102641_+ | SINE | Alu | Name=AluSx |
| ADediting_192429 | chr10_3102675_+ | SINE | Alu | Name=AluSx |
| ADediting_192432 | chr10_3120729_+ | SINE | Alu | Name=AluJb |
| ADediting_192433 | chr10_3120734_+ | SINE | Alu | Name=AluJb |
| ADediting_192434 | chr10_3120739_+ | SINE | Alu | Name=AluJb |
| ADediting_192435 | chr10_3120746_+ | SINE | Alu | Name=AluJb |
| ADediting_192436 | chr10_3121915_+ | SINE | Alu | Name=AluJb |
| ADediting_192437 | chr10_3121934_+ | SINE | Alu | Name=AluJb |
| ADediting_192516 | chr10_3136143_+ | SINE | Alu | Name=AluSc |
| ADediting_1523291 | chr10_3070870_+ | SINE | Alu | Name=AluJr |
| ADediting_1523292 | chr10_3070957_+ | SINE | Alu | Name=AluJr |
| ADediting_1523294 | chr10_3133524_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1605412 | chr10_3133510_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1605413 | chr10_3133511_+ | SINE | Alu | Name=AluSx1 |
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RNA A-to-I editing events in the alternative splicing sites for PFKP |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| ME2 | ADediting_192438 | chr10_3125611_+ | 3125606:3125614 | 5ss | 3i | CCGGTAAGT | 10.91 | CCGGTGAGT | 10.90 |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for PFKP |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for PFKP |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for PFKP |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1556067 | chr19_40282625_- | ENSG00000067057.17 | ENST00000381075.6 | PFKP-202 | hsa-miR-641 | chr10 | 3136740 | 3136746 | 7mer-1a | 3136723 | 3136746 | 142 | -15.51 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000067057.17 | ENST00000381125.9 | PFKP-203 | hsa-miR-641 | chr10 | 3136740 | 3136746 | 7mer-1a | 3136723 | 3136746 | 142 | -15.51 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000067057.17 | ENST00000415005.6 | PFKP-206 | hsa-miR-641 | chr10 | 3136740 | 3136746 | 7mer-1a | 3136723 | 3136746 | 142 | -15.51 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_496066 | chr15_66496985_- | ENSG00000067057.17 | ENST00000415005.6 | PFKP-206 | hsa-miR-4512 | chr10 | 3137687 | 3137694 | 8mer-1a | 3137673 | 3137694 | 143 | -12.67 |
| ADediting_496066 | chr15_66496985_- | ENSG00000067057.17 | ENST00000433193.2 | PFKP-208 | hsa-miR-4512 | chr10 | 3137687 | 3137694 | 8mer-1a | 3137673 | 3137694 | 143 | -12.67 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for PFKP |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for PFKP |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| PCC | ADediting_192262 | chr10_3070948_+ | 1.44629291230398e-05 | 0.308146429803769 | 0.000252575611557872 | 0.261884311856107 | 0.308226987917687 | 0.074113644086476 |
| DLPFC | ADediting_192264 | chr10_3071013_+ | 6.4505023415887e-05 | 0.224933983876162 | 2.07631264056952e-08 | 0.311666456530559 | 0.320353032341635 | 0.0566236743820647 |
| DLPFC | ADediting_192267 | chr10_3073917_+ | 0.0825825312918815 | 0.0987499864137521 | 0.527635785267281 | -0.0360073816896564 | 7.52338839080452e-30 | 0.584958259147091 |
| DLPFC | ADediting_192273 | chr10_3074037_+ | 0.91467090132295 | 0.00611027240816665 | 0.165967149659024 | -0.0788745742054274 | 4.07902814545014e-10 | 0.345438473014206 |
| DLPFC | ADediting_192299 | chr10_3080263_+ | 0.837909153493455 | -0.0116654486304534 | 0.0707003507799405 | -0.102796441836726 | 2.84076983377273e-09 | 0.329275180542533 |
| CER | ADediting_192432 | chr10_3120729_+ | 0.00205499156256334 | 0.249746854842924 | 8.08649681143927e-07 | 0.389996000744724 | 0.0565117733426723 | 0.156061529435327 |
| CER | ADediting_192440 | chr10_3125985_+ | 0.0273303899066811 | 0.180211434171249 | 6.89080457826861e-07 | 0.392258931118366 | 0.000833410100271812 | 0.270001929961004 |
| CER | ADediting_192441 | chr10_3125988_+ | 0.0250236316957747 | 0.182963106963265 | 1.04666642343717e-06 | 0.386311311868157 | 0.0432835016079909 | 0.165257112641982 |
| TCX | ADediting_192442 | chr10_3125990_+ | 2.11598034442481e-05 | 0.339659944662684 | 0.00699516584304514 | 0.219361420154374 | 0.12134534209404 | 0.127037366052103 |
| CER | ADediting_192443 | chr10_3125991_+ | 0.00160346860270417 | 0.255475269179797 | 4.43249724254971e-08 | 0.428666302004197 | 0.000429283583479807 | 0.283954502714783 |
| CER | ADediting_192444 | chr10_3126006_+ | 1.39701776177136e-05 | 0.346556385704402 | 1.00770371494708e-09 | 0.472733643347673 | 7.59384816097649e-05 | 0.31734043040444 |
| CER | ADediting_192445 | chr10_3126014_+ | 0.00022493485055765 | 0.296887219730374 | 8.06908115021947e-08 | 0.421076853757353 | 0.00307313246289001 | 0.240170693074995 |
| DLPFC | ADediting_192448 | chr10_3126502_+ | 0.0003813176195929 | 0.200535698903433 | 2.86529948241693e-08 | 0.30870460849678 | 0.322844696581606 | 0.0563333258703558 |
| CER | ADediting_192448 | chr10_3126502_+ | 4.05525798106228e-05 | 0.328514448989829 | 1.10143239351159e-08 | 0.445617898552206 | 0.0445121903265056 | 0.164311154495044 |
| TCX | ADediting_192448 | chr10_3126502_+ | 0.00453961678087735 | 0.230521417178015 | 3.46904039455198e-05 | 0.331229131981768 | 0.241758753340756 | 0.0961620218506298 |
| CER | ADediting_192449 | chr10_3126514_+ | 0.001192117754578 | 0.262156361005505 | 1.0054624756521e-06 | 0.386887854970697 | 0.0115239657458453 | 0.205788082196788 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 1.01608313009786e-50 | 0.719628144365805 | 8.8148390064588e-70 | 0.798241050016335 | 0.0121504092523912 | 0.142279835394337 |
| AC | 1.54407988499042e-39 | 0.70929824857498 | 2.01757375552877e-29 | 0.633212805450451 | 1.54766362255118e-08 | 0.348215821765905 |
| PCC | 9.16612783412367e-50 | 0.829817211509488 | 6.38388698259605e-60 | 0.86991324345911 | 0.843232374462361 | 0.0144032597374782 |
| CER | 4.05876769412399e-08 | 0.429766642512274 | 4.79869096310349e-25 | 0.71785697798406 | 5.59020024866379e-05 | 0.322851372414048 |
| TCX | 1.69299046586603e-18 | 0.637744095723953 | 2.38788464505357e-16 | 0.605076806652277 | 0.762387772033162 | -0.0248909040233096 |
| FP | 9.92633004837009e-13 | 0.501563165315872 | 4.96489504872749e-19 | 0.60335373606555 | 0.0321464898211055 | 0.16068055564768 |
| IFG | 0.000449930397084461 | 0.648883013870836 | 4.53804786043803e-05 | 0.722452384720433 | 0.887662616907174 | 0.0297704424824834 |
| PG | 8.47424880546278e-18 | 0.575549513420684 | 6.91703770351624e-17 | 0.562130075402016 | 0.664269807456416 | -0.0320320744594855 |
| STG | 3.23958940166632e-12 | 0.669805337326848 | 1.89556926155243e-14 | 0.716142309760558 | 0.582807419524207 | -0.0607876646581586 |
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Relation with AD stages for PFKP |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_192440 | chr10_3125985_+ | 0.000417426739306344 | 0.333657892380025 |
| CER | ADediting_192441 | chr10_3125988_+ | 4.83336804215087e-05 | 0.380620350022839 |
| CER | ADediting_192442 | chr10_3125990_+ | 0.000997437180736742 | 0.312371395538598 |
| CER | ADediting_192443 | chr10_3125991_+ | 3.91902376293502e-07 | 0.465221390508864 |
| CER | ADediting_192444 | chr10_3126006_+ | 4.30552187991401e-05 | 0.382946007772612 |
| CER | ADediting_192449 | chr10_3126514_+ | 8.63375517616333e-06 | 0.413573562673397 |
| TCX | ADediting_192442 | chr10_3125990_+ | 0.000155358155547073 | 0.359287984831169 |
| TCX | ADediting_192446 | chr10_3126485_+ | 0.00021260755400811 | 0.352293389786584 |
| TCX | ADediting_192447 | chr10_3126487_+ | 2.63430993162397e-05 | 0.396098394891283 |
| IFG | ADediting_192448 | chr10_3126502_+ | 0.029793784342784 | 0.434935925909225 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 8.47497917759228e-10 | 0.547799461891857 |
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RelatedDrugs for PFKP |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PFKP |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| PFKP | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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