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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for NCKIPSD

check button Gene summary
Gene informationGene symbol

NCKIPSD

Gene ID

51517

Gene nameNCK interacting protein with SH3 domain
SynonymsAF3P21|DIP|DIP1|ORF1|SPIN90|VIP54|WASLBP|WISH
Cytomap

3p21.31

Type of geneprotein-coding
DescriptionNCK-interacting protein with SH3 domain54 kDa VacA-interacting protein54 kDa vimentin-interacting protein90 kDa SH3 protein interacting with NckSH3 adapter protein SPIN90SH3 protein interacting with Nck, 90 kDaWASP-interacting SH3-domain proteindia
Modification date20200313
UniProtAcc

Q9NZQ3,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for NCKIPSD

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_1071405(48675653, -), ADediting_1071406(48675679, -), ADediting_1071407(48675680, -), ADediting_1071408(48675702, -), ADediting_1071409(48675706, -), ADediting_1071410(48675709, -), ADediting_1071411(48675749, -), ADediting_1071412(48675759, -), ADediting_1071413(48675762, -), ADediting_1071414(48675763, -), ADediting_1071415(48675777, -), ADediting_1071416(48675783, -), ADediting_1071417(48675810, -), ADediting_1071418(48675819, -), ADediting_1071419(48676515, -), ADediting_1071420(48676564, -), ADediting_1071421(48676565, -), ADediting_1071422(48676573, -), ADediting_1071423(48676578, -), ADediting_1071424(48676588, -), ADediting_1071425(48676595, -), ADediting_1071426(48676602, -), ADediting_1071427(48676609, -), ADediting_1071428(48676612, -), ADediting_1071429(48676613, -), ADediting_1071430(48676618, -), ADediting_1071431(48676619, -), ADediting_1071432(48676625, -), ADediting_1071433(48676629, -), ADediting_1071434(48676692, -), ADediting_1071435(48676711, -), ADediting_1071436(48676712, -), ADediting_1071437(48676730, -), ADediting_1071438(48676742, -), ADediting_1071439(48676765, -), ADediting_1071440(48676766, -), ADediting_1071441(48676768, -), ADediting_1071442(48676774, -), ADediting_1071443(48676782, -), ADediting_1071444(48676831, -), ADediting_1071445(48676833, -), ADediting_1071446(48676838, -), ADediting_1071447(48676839, -), ADediting_1071448(48676843, -), ADediting_1071449(48676867, -), ADediting_1071450(48676868, -), ADediting_1071451(48676876, -), ADediting_1071452(48676882, -), ADediting_1071453(48676886, -), ADediting_1071454(48676892, -), ADediting_1071455(48676899, -), ADediting_1071456(48676908, -), ADediting_1071457(48676909, -), ADediting_1071458(48676927, -), ADediting_1071459(48676935, -), ADediting_1071460(48676938, -), ADediting_1071461(48676939, -), ADediting_1071462(48676941, -), ADediting_1071463(48676942, -), ADediting_1071464(48676946, -), ADediting_1071465(48676965, -), ADediting_1071466(48676969, -), ADediting_1071467(48676990, -), ADediting_1071468(48676993, -), ADediting_1071469(48677000, -), ADediting_1071470(48677001, -), ADediting_1071471(48677004, -), ADediting_1071472(48677009, -), ADediting_1071473(48677014, -), ADediting_1071474(48677033, -), ADediting_1071475(48677044, -), ADediting_1071476(48677049, -), ADediting_1071477(48677050, -), ADediting_1071478(48677119, -), ADediting_1071479(48677123, -), ADediting_1071480(48677130, -), ADediting_1071481(48677132, -), ADediting_1071482(48677144, -), ADediting_1071483(48677145, -), ADediting_1071484(48677154, -), ADediting_1071485(48677163, -), ADediting_1071486(48677167, -), ADediting_1071487(48677168, -), ADediting_1071488(48677172, -), ADediting_1071489(48677197, -), ADediting_1071490(48677217, -), ADediting_1071491(48677223, -), ADediting_1071492(48677226, -), ADediting_1071493(48677233, -), ADediting_1071494(48677240, -), ADediting_1071495(48677248, -), ADediting_1071496(48677260, -), ADediting_1071497(48677264, -), ADediting_1071498(48677266, -), ADediting_1071499(48677279, -), ADediting_1071500(48677288, -), ADediting_1071501(48677305, -), ADediting_1071502(48677306, -), ADediting_1071503(48677325, -), ADediting_1071504(48677331, -), ADediting_1071505(48677341, -), ADediting_1071506(48677344, -), ADediting_1071507(48677362, -), ADediting_1071508(48677363, -), ADediting_1574675(48677372, -),

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RNA editing positional annotations for NCKIPSD using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_1071405chr3_48675653_-intronic
ADediting_1071406chr3_48675679_-intronic
ADediting_1071407chr3_48675680_-intronic
ADediting_1071408chr3_48675702_-intronic
ADediting_1071409chr3_48675706_-intronic
ADediting_1071410chr3_48675709_-intronic
ADediting_1071411chr3_48675749_-intronic
ADediting_1071412chr3_48675759_-intronic
ADediting_1071413chr3_48675762_-intronic
ADediting_1071414chr3_48675763_-intronic
ADediting_1071415chr3_48675777_-intronic
ADediting_1071416chr3_48675783_-intronic
ADediting_1071417chr3_48675810_-intronic
ADediting_1071418chr3_48675819_-intronic
ADediting_1071419chr3_48676515_-intronic
ADediting_1071420chr3_48676564_-intronic
ADediting_1071421chr3_48676565_-intronic
ADediting_1071422chr3_48676573_-intronic
ADediting_1071423chr3_48676578_-intronic
ADediting_1071424chr3_48676588_-intronic
ADediting_1071425chr3_48676595_-intronic
ADediting_1071426chr3_48676602_-intronic
ADediting_1071427chr3_48676609_-intronic
ADediting_1071428chr3_48676612_-intronic
ADediting_1071429chr3_48676613_-intronic
ADediting_1071430chr3_48676618_-intronic
ADediting_1071431chr3_48676619_-intronic
ADediting_1071432chr3_48676625_-intronic
ADediting_1071433chr3_48676629_-intronic
ADediting_1071434chr3_48676692_-intronic
ADediting_1071435chr3_48676711_-intronic
ADediting_1071436chr3_48676712_-intronic
ADediting_1071437chr3_48676730_-intronic
ADediting_1071438chr3_48676742_-intronic
ADediting_1071439chr3_48676765_-intronic
ADediting_1071440chr3_48676766_-intronic
ADediting_1071441chr3_48676768_-intronic
ADediting_1071442chr3_48676774_-intronic
ADediting_1071443chr3_48676782_-intronic
ADediting_1071444chr3_48676831_-intronic
ADediting_1071445chr3_48676833_-intronic
ADediting_1071446chr3_48676838_-intronic
ADediting_1071447chr3_48676839_-intronic
ADediting_1071448chr3_48676843_-intronic
ADediting_1071449chr3_48676867_-intronic
ADediting_1071450chr3_48676868_-intronic
ADediting_1071451chr3_48676876_-intronic
ADediting_1071452chr3_48676882_-intronic
ADediting_1071453chr3_48676886_-intronic
ADediting_1071454chr3_48676892_-intronic
ADediting_1071455chr3_48676899_-intronic
ADediting_1071456chr3_48676908_-intronic
ADediting_1071457chr3_48676909_-intronic
ADediting_1071458chr3_48676927_-intronic
ADediting_1071459chr3_48676935_-intronic
ADediting_1071460chr3_48676938_-intronic
ADediting_1071461chr3_48676939_-intronic
ADediting_1071462chr3_48676941_-intronic
ADediting_1071463chr3_48676942_-intronic
ADediting_1071464chr3_48676946_-intronic
ADediting_1071465chr3_48676965_-intronic
ADediting_1071466chr3_48676969_-intronic
ADediting_1071467chr3_48676990_-intronic
ADediting_1071468chr3_48676993_-intronic
ADediting_1071469chr3_48677000_-intronic
ADediting_1071470chr3_48677001_-intronic
ADediting_1071471chr3_48677004_-intronic
ADediting_1071472chr3_48677009_-intronic
ADediting_1071473chr3_48677014_-intronic
ADediting_1071474chr3_48677033_-intronic
ADediting_1071475chr3_48677044_-intronic
ADediting_1071476chr3_48677049_-intronic
ADediting_1071477chr3_48677050_-intronic
ADediting_1071478chr3_48677119_-intronic
ADediting_1071479chr3_48677123_-intronic
ADediting_1071480chr3_48677130_-intronic
ADediting_1071481chr3_48677132_-intronic
ADediting_1071482chr3_48677144_-intronic
ADediting_1071483chr3_48677145_-intronic
ADediting_1071484chr3_48677154_-intronic
ADediting_1071485chr3_48677163_-intronic
ADediting_1071486chr3_48677167_-intronic
ADediting_1071487chr3_48677168_-intronic
ADediting_1071488chr3_48677172_-intronic
ADediting_1071489chr3_48677197_-intronic
ADediting_1071490chr3_48677217_-intronic
ADediting_1071491chr3_48677223_-intronic
ADediting_1071492chr3_48677226_-intronic
ADediting_1071493chr3_48677233_-intronic
ADediting_1071494chr3_48677240_-intronic
ADediting_1071495chr3_48677248_-intronic
ADediting_1071496chr3_48677260_-intronic
ADediting_1071497chr3_48677264_-intronic
ADediting_1071498chr3_48677266_-intronic
ADediting_1071499chr3_48677279_-intronic
ADediting_1071500chr3_48677288_-intronic
ADediting_1071501chr3_48677305_-intronic
ADediting_1071502chr3_48677306_-intronic
ADediting_1071503chr3_48677325_-intronic
ADediting_1071504chr3_48677331_-intronic
ADediting_1071505chr3_48677341_-intronic
ADediting_1071506chr3_48677344_-intronic
ADediting_1071507chr3_48677362_-intronic
ADediting_1071508chr3_48677363_-intronic
ADediting_1574675chr3_48677372_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_1071405chr3_48675653_-SINEAluName=AluSz
ADediting_1071406chr3_48675679_-SINEAluName=AluSz
ADediting_1071407chr3_48675680_-SINEAluName=AluSz
ADediting_1071408chr3_48675702_-SINEAluName=AluSz
ADediting_1071409chr3_48675706_-SINEAluName=AluSz
ADediting_1071410chr3_48675709_-SINEAluName=AluSz
ADediting_1071411chr3_48675749_-SINEAluName=AluSz
ADediting_1071412chr3_48675759_-SINEAluName=AluSz
ADediting_1071413chr3_48675762_-SINEAluName=AluSz
ADediting_1071414chr3_48675763_-SINEAluName=AluSz
ADediting_1071415chr3_48675777_-SINEAluName=AluSz
ADediting_1071416chr3_48675783_-SINEAluName=AluSz
ADediting_1071417chr3_48675810_-SINEAluName=AluSz
ADediting_1071418chr3_48675819_-SINEAluName=AluSz
ADediting_1071419chr3_48676515_-SINEAluName=AluJb
ADediting_1071420chr3_48676564_-SINEAluName=AluJb
ADediting_1071421chr3_48676565_-SINEAluName=AluJb
ADediting_1071422chr3_48676573_-SINEAluName=AluJb
ADediting_1071423chr3_48676578_-SINEAluName=AluJb
ADediting_1071424chr3_48676588_-SINEAluName=AluJb
ADediting_1071425chr3_48676595_-SINEAluName=AluJb
ADediting_1071426chr3_48676602_-SINEAluName=AluJb
ADediting_1071427chr3_48676609_-SINEAluName=AluJb
ADediting_1071428chr3_48676612_-SINEAluName=AluJb
ADediting_1071429chr3_48676613_-SINEAluName=AluJb
ADediting_1071430chr3_48676618_-SINEAluName=AluJb
ADediting_1071431chr3_48676619_-SINEAluName=AluJb
ADediting_1071432chr3_48676625_-SINEAluName=AluJb
ADediting_1071433chr3_48676629_-SINEAluName=AluJb
ADediting_1071434chr3_48676692_-SINEAluName=AluJb
ADediting_1071435chr3_48676711_-SINEAluName=AluJb
ADediting_1071436chr3_48676712_-SINEAluName=AluJb
ADediting_1071437chr3_48676730_-SINEAluName=AluJb
ADediting_1071438chr3_48676742_-SINEAluName=AluJb
ADediting_1071439chr3_48676765_-SINEAluName=AluJb
ADediting_1071440chr3_48676766_-SINEAluName=AluJb
ADediting_1071441chr3_48676768_-SINEAluName=AluJb
ADediting_1071442chr3_48676774_-SINEAluName=AluJb
ADediting_1071443chr3_48676782_-SINEAluName=AluJb
ADediting_1071444chr3_48676831_-SINEAluName=AluSx1
ADediting_1071445chr3_48676833_-SINEAluName=AluSx1
ADediting_1071446chr3_48676838_-SINEAluName=AluSx1
ADediting_1071447chr3_48676839_-SINEAluName=AluSx1
ADediting_1071448chr3_48676843_-SINEAluName=AluSx1
ADediting_1071449chr3_48676867_-SINEAluName=AluSx1
ADediting_1071450chr3_48676868_-SINEAluName=AluSx1
ADediting_1071451chr3_48676876_-SINEAluName=AluSx1
ADediting_1071452chr3_48676882_-SINEAluName=AluSx1
ADediting_1071453chr3_48676886_-SINEAluName=AluSx1
ADediting_1071454chr3_48676892_-SINEAluName=AluSx1
ADediting_1071455chr3_48676899_-SINEAluName=AluSx1
ADediting_1071456chr3_48676908_-SINEAluName=AluSx1
ADediting_1071457chr3_48676909_-SINEAluName=AluSx1
ADediting_1071458chr3_48676927_-SINEAluName=AluSx1
ADediting_1071459chr3_48676935_-SINEAluName=AluSx1
ADediting_1071460chr3_48676938_-SINEAluName=AluSx1
ADediting_1071461chr3_48676939_-SINEAluName=AluSx1
ADediting_1071462chr3_48676941_-SINEAluName=AluSx1
ADediting_1071463chr3_48676942_-SINEAluName=AluSx1
ADediting_1071464chr3_48676946_-SINEAluName=AluSx1
ADediting_1071465chr3_48676965_-SINEAluName=AluSx1
ADediting_1071466chr3_48676969_-SINEAluName=AluSx1
ADediting_1071467chr3_48676990_-SINEAluName=AluSx1
ADediting_1071468chr3_48676993_-SINEAluName=AluSx1
ADediting_1071469chr3_48677000_-SINEAluName=AluSx1
ADediting_1071470chr3_48677001_-SINEAluName=AluSx1
ADediting_1071471chr3_48677004_-SINEAluName=AluSx1
ADediting_1071472chr3_48677009_-SINEAluName=AluSx1
ADediting_1071473chr3_48677014_-SINEAluName=AluSx1
ADediting_1071474chr3_48677033_-SINEAluName=AluSx1
ADediting_1071475chr3_48677044_-SINEAluName=AluSx1
ADediting_1071476chr3_48677049_-SINEAluName=AluSx1
ADediting_1071477chr3_48677050_-SINEAluName=AluSx1
ADediting_1071478chr3_48677119_-SINEAluName=AluSx1
ADediting_1071479chr3_48677123_-SINEAluName=AluSx1
ADediting_1071480chr3_48677130_-SINEAluName=AluSx1
ADediting_1071481chr3_48677132_-SINEAluName=AluSx1
ADediting_1071482chr3_48677144_-SINEAluName=AluSx1
ADediting_1071483chr3_48677145_-SINEAluName=AluSx1
ADediting_1071484chr3_48677154_-SINEAluName=AluSx1
ADediting_1071485chr3_48677163_-SINEAluName=AluSx1
ADediting_1071486chr3_48677167_-SINEAluName=AluSx1
ADediting_1071487chr3_48677168_-SINEAluName=AluSx1
ADediting_1071488chr3_48677172_-SINEAluName=AluSx1
ADediting_1071489chr3_48677197_-SINEAluName=AluSx1
ADediting_1071490chr3_48677217_-SINEAluName=AluSx1
ADediting_1071491chr3_48677223_-SINEAluName=AluSx1
ADediting_1071492chr3_48677226_-SINEAluName=AluSx1
ADediting_1071493chr3_48677233_-SINEAluName=AluSx1
ADediting_1071494chr3_48677240_-SINEAluName=AluSx1
ADediting_1071495chr3_48677248_-SINEAluName=AluSx1
ADediting_1071496chr3_48677260_-SINEAluName=AluSx1
ADediting_1071497chr3_48677264_-SINEAluName=AluSx1
ADediting_1071498chr3_48677266_-SINEAluName=AluSx1
ADediting_1071499chr3_48677279_-SINEAluName=AluSx1
ADediting_1071500chr3_48677288_-SINEAluName=AluSx1
ADediting_1071501chr3_48677305_-SINEAluName=AluSx1
ADediting_1071502chr3_48677306_-SINEAluName=AluSx1
ADediting_1071503chr3_48677325_-SINEAluName=AluSx1
ADediting_1071504chr3_48677331_-SINEAluName=AluSx1
ADediting_1071505chr3_48677341_-SINEAluName=AluSx1
ADediting_1071506chr3_48677344_-SINEAluName=AluSx1
ADediting_1071507chr3_48677362_-SINEAluName=AluSx1
ADediting_1071508chr3_48677363_-SINEAluName=AluSx1
ADediting_1574675chr3_48677372_-SINEAluName=AluSx1

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RNA A-to-I editing events in the alternative splicing sites for NCKIPSD

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for NCKIPSD

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for NCKIPSD

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for NCKIPSD


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1631458chr19_40282624_-ENSG00000213672.8ENST00000294129.7NCKIPSD-201hsa-miR-641chr348674093486740997mer-m84867409248674115158-20.19
ADediting_1631458chr19_40282624_-ENSG00000213672.8ENST00000416649.6NCKIPSD-204hsa-miR-641chr348674093486740997mer-m84867409248674115158-20.19

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337757chr7_5495852_-ENSG00000213672.8ENST00000294129.7NCKIPSD-201hsa-miR-589-3pchr348674348486743547mer-m84867434748674370155-25.06
ADediting_1337757chr7_5495852_-ENSG00000213672.8ENST00000416649.6NCKIPSD-204hsa-miR-589-3pchr348674348486743547mer-m84867434748674370155-25.06
ADediting_291761chr11_93733708_-ENSG00000213672.8ENST00000294129.7NCKIPSD-201hsa-miR-1304-3pchr348674108486741147mer-m84867410748674128147-15.41
ADediting_291761chr11_93733708_-ENSG00000213672.8ENST00000416649.6NCKIPSD-204hsa-miR-1304-3pchr348674108486741147mer-m84867410748674128147-15.41

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for NCKIPSD

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for NCKIPSD

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
TCXADediting_1071424chr3_48676588_-0.003068917337882530.2402039838794590.0001272418936486320.3078044069010730.7412510256707490.0271828959122575
DLPFCADediting_1071444chr3_48676831_-2.23642188154633e-050.2382936277471374.19583172449719e-090.3259106075354110.02452474309499540.127716148731595
DLPFCADediting_1071445chr3_48676833_-1.22112542336482e-070.294949973821675.98897094679379e-090.3228046855824770.01130539800920890.143704278711855
CERADediting_1071446chr3_48676838_-0.005382826809844070.2261854456074076.2001844482389e-050.3210001097753570.001780616311179930.253071424674074
CERADediting_1071447chr3_48676839_-0.08827184423176760.1396641501970468.37302992250526e-050.3155604250134240.007775430017032110.216550893535634
CERADediting_1071449chr3_48676867_-0.009080889745907680.2123644637251285.55541870930394e-060.3613187405051990.0004494201952781710.283013425580025
CERADediting_1071452chr3_48676882_-0.001022496445082990.2655491613766782.54780457489611e-080.4355193580470280.03555906017750630.171781341110926
TCXADediting_1071452chr3_48676882_-0.3293837188808860.08017991907870929.21740746184422e-060.3533047821509670.435125253855460.0641948405551297
CERADediting_1071456chr3_48676908_-0.007035238810754140.2192104499093150.000162349904676810.3031876228387940.1376774032300950.121775725092956
CERADediting_1071457chr3_48676909_-5.79943100730266e-050.3221959151615442.6478809181071e-060.3726715311645610.3235716001243130.0811458591017047
CERADediting_1071458chr3_48676927_-0.0005737774058125540.2779421775783382.02208133338619e-060.3766979678120180.5940241137024350.043866388884232
TCXADediting_1071458chr3_48676927_-0.003578084562570590.2364528819687143.57278042836646e-060.3681335228987240.896415084079662-0.0107194424016067
TCXADediting_1071461chr3_48676939_-0.0001760181575751770.301638985867730.02585495231413070.1819473409772550.3027724557978930.0846977133377136
CERADediting_1071469chr3_48677000_-0.0002836113046280270.2923190902152592.62071132284389e-060.3728265458651710.2529034217994420.0939313658318709
CERADediting_1071471chr3_48677004_-3.71132991661377e-070.400855450729851.43949912974448e-110.5157361223499760.05307049209967650.158265832895698
TCXADediting_1071471chr3_48677004_-8.61589893031066e-050.315037233101666.03375223753545e-050.321487668381670.06783079655466590.149514336579695
CERADediting_1071473chr3_48677014_-5.02365267827497e-050.3247490141954551.00305917099362e-050.3519451876250690.6275110926728530.0399373884589107
CERADediting_1071474chr3_48677033_-2.74768980479205e-070.4049461415204855.05108494818835e-120.5254750176740310.001193588959936830.262128917872097
CERADediting_1071475chr3_48677044_-0.003110288249395340.2398790085865162.24579516607998e-070.4076603854543940.05428112449645840.157477256719386
CERADediting_1071476chr3_48677049_-0.0002781793777845620.2927031297258821.44314011707174e-060.3816603290429130.3069390394324920.0839737109742406
CERADediting_1071477chr3_48677050_-0.0004050936709939090.2851405139385262.04187515595363e-050.3402585510409190.27803748062270.0891377712102507
CERADediting_1071482chr3_48677144_-0.000646295495185640.2754362254492269.46494231967675e-060.3528792911278560.4019078822176080.0689354828708151
CERADediting_1071484chr3_48677154_-8.46994609590652e-050.3153499660439263.6324925926583e-090.4584899952507720.006665245739476110.220634451548743
TCXADediting_1071484chr3_48677154_-0.01570354450291370.1969554175890151.39908143081445e-050.3465321522245930.411359502696553-0.0675639969929884
CERADediting_1071485chr3_48677163_-0.09914420675609720.135153764641369.38736999030512e-050.3134622649625670.002832264696207740.242142701100802
CERADediting_1071486chr3_48677167_-3.05865450395954e-050.3333996923310523.42353293728128e-070.4019591582141350.147882396752820.118726170885023
CERADediting_1071487chr3_48677168_-0.0001019449871061440.3119390635948789.37381656166942e-060.3530346911858710.1362549909460090.122214326776219
CERADediting_1071489chr3_48677197_-0.0005848810994221660.2775401872109242.96617988185474e-070.4039101804417470.006276701210460320.222207678164953
CERADediting_1071500chr3_48677288_-0.0001600501669395520.3034600547369582.09903995810935e-070.4085644416923320.001920682956604450.251320241485221
CERADediting_1071503chr3_48677325_-1.32116455300636e-050.3474714270505055.06011412771134e-080.4270046349697870.03589809293411630.171471044496339
TCXADediting_1071503chr3_48677325_-0.001074309876035230.2644612787505849.62399975869045e-100.4732326846922710.35706762998065-0.0757220646427424
CERADediting_1071507chr3_48677362_-0.0007644724194972970.2718597327879072.87329344499063e-080.4340442546776090.02097495400181820.188368164891079
TCXADediting_1071507chr3_48677362_-0.0105143455633170.2083409854579261.3040335968829e-080.4436108919171450.307082479450105-0.083948901456306

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC6.68509369269002e-660.7845774098512271.27517307661306e-1140.9023750650446920.05625386913415140.108545464620413
AC5.67490413932745e-880.8930195443314863.79882210056347e-760.864763875449462.80613478491926e-080.342261152523732
PCC2.76696339510216e-650.8868505970191241.45203976010777e-880.9374746389085350.03187159367316590.155356130120125
CER6.51750649267529e-160.5979611146014051.89571247895803e-150.5901965806310690.0118574777156790.204987916542865
TCX2.00435799065404e-300.7678886896790893.80207547806507e-330.7892023277101030.539678237728136-0.0504659529295612
FP6.15704773249626e-470.8321575453648131.1792610465535e-240.6711327391994720.001012628456293160.244346785327297
IFG8.63229903453702e-070.8113284510436595.98237925519351e-060.7727304065513070.4443432333106110.160184935627588
PG0.007829399563007570.1944384402618894.80372974795462e-070.3591417984597880.417371759888757-0.0598145893658894
STG7.948428485921e-250.8525839343681061.12125872480252e-130.7010901967251760.6580705837875880.0489943886899202

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Relation with AD stages for NCKIPSD

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
CERADediting_1071449chr3_48676867_-0.0001735706403546490.353659824934098
CERADediting_1071471chr3_48677004_-3.69346682935915e-050.386002776822826
CERADediting_1071474chr3_48677033_-2.92451404485656e-050.390599163259321

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
CER0.00102495264062040.311680762975548
PG2.03429062606241e-05-0.306932646255156

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RelatedDrugs for NCKIPSD

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for NCKIPSD

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource