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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for ATP5PB |
 Gene summary |
| Gene information | Gene symbol | ATP5PB | Gene ID | 515 |
| Gene name | ATP synthase peripheral stalk-membrane subunit b | |
| Synonyms | ATP5F1|PIG47 | |
| Cytomap | 1p13.2 | |
| Type of gene | protein-coding | |
| Description | ATP synthase F(0) complex subunit B1, mitochondrialATP synthase B chain, mitochondrialATP synthase proton-transporting mitochondrial F(0) complex subunit B1ATP synthase subunit b, mitochondrialATP synthase, H+ transporting, mitochondrial F0 complex, s | |
| Modification date | 20200313 | |
| UniProtAcc | P24539, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| ATP5PB | GO:0042776 | mitochondrial ATP synthesis coupled proton transport | 12110673 |
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RNA A-to-I events for ATP5PB |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_7135(111452044, +), ADediting_7136(111454476, +), ADediting_7137(111454478, +), ADediting_7138(111454480, +), ADediting_7139(111454551, +), ADediting_7140(111461671, +), ADediting_7141(111461690, +), ADediting_7142(111461700, +), ADediting_7143(111461708, +), ADediting_7144(111461713, +), ADediting_7145(111461714, +), ADediting_7146(111461718, +), ADediting_7147(111461747, +), ADediting_7148(111461748, +), ADediting_7149(111461749, +), ADediting_7150(111461754, +), ADediting_7151(111461781, +), ADediting_7152(111461790, +), ADediting_7153(111461803, +), ADediting_7154(111461821, +), ADediting_7155(111461822, +), ADediting_7156(111461826, +), ADediting_7157(111461856, +), ADediting_7158(111461861, +), ADediting_7159(111461883, +), |
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RNA editing positional annotations for ATP5PB using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_7135 | chr1_111452044_+ | intronic |
| ADediting_7136 | chr1_111454476_+ | intronic |
| ADediting_7137 | chr1_111454478_+ | intronic |
| ADediting_7138 | chr1_111454480_+ | intronic |
| ADediting_7139 | chr1_111454551_+ | intronic |
| ADediting_7140 | chr1_111461671_+ | UTR3 |
| ADediting_7141 | chr1_111461690_+ | UTR3 |
| ADediting_7142 | chr1_111461700_+ | UTR3 |
| ADediting_7143 | chr1_111461708_+ | UTR3 |
| ADediting_7144 | chr1_111461713_+ | UTR3 |
| ADediting_7145 | chr1_111461714_+ | UTR3 |
| ADediting_7146 | chr1_111461718_+ | UTR3 |
| ADediting_7147 | chr1_111461747_+ | UTR3 |
| ADediting_7148 | chr1_111461748_+ | UTR3 |
| ADediting_7149 | chr1_111461749_+ | UTR3 |
| ADediting_7150 | chr1_111461754_+ | UTR3 |
| ADediting_7151 | chr1_111461781_+ | UTR3 |
| ADediting_7152 | chr1_111461790_+ | UTR3 |
| ADediting_7153 | chr1_111461803_+ | UTR3 |
| ADediting_7154 | chr1_111461821_+ | UTR3 |
| ADediting_7155 | chr1_111461822_+ | UTR3 |
| ADediting_7156 | chr1_111461826_+ | UTR3 |
| ADediting_7157 | chr1_111461856_+ | UTR3 |
| ADediting_7158 | chr1_111461861_+ | UTR3 |
| ADediting_7159 | chr1_111461883_+ | UTR3 |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_7135 | chr1_111452044_+ | SINE | Alu | Name=AluJr |
| ADediting_7136 | chr1_111454476_+ | SINE | Alu | Name=AluJb |
| ADediting_7137 | chr1_111454478_+ | SINE | Alu | Name=AluJb |
| ADediting_7138 | chr1_111454480_+ | SINE | Alu | Name=AluJb |
| ADediting_7139 | chr1_111454551_+ | SINE | Alu | Name=AluJb |
| ADediting_7140 | chr1_111461671_+ | SINE | Alu | Name=AluSx1 |
| ADediting_7141 | chr1_111461690_+ | SINE | Alu | Name=AluSx1 |
| ADediting_7142 | chr1_111461700_+ | SINE | Alu | Name=AluSx1 |
| ADediting_7143 | chr1_111461708_+ | SINE | Alu | Name=AluSx1 |
| ADediting_7144 | chr1_111461713_+ | SINE | Alu | Name=AluSx1 |
| ADediting_7145 | chr1_111461714_+ | SINE | Alu | Name=AluSx1 |
| ADediting_7146 | chr1_111461718_+ | SINE | Alu | Name=AluSx1 |
| ADediting_7147 | chr1_111461747_+ | SINE | Alu | Name=AluSx1 |
| ADediting_7148 | chr1_111461748_+ | SINE | Alu | Name=AluSx1 |
| ADediting_7149 | chr1_111461749_+ | SINE | Alu | Name=AluSx1 |
| ADediting_7150 | chr1_111461754_+ | SINE | Alu | Name=AluSx1 |
| ADediting_7151 | chr1_111461781_+ | SINE | Alu | Name=AluSx1 |
| ADediting_7152 | chr1_111461790_+ | SINE | Alu | Name=AluSx1 |
| ADediting_7153 | chr1_111461803_+ | SINE | Alu | Name=AluSx1 |
| ADediting_7154 | chr1_111461821_+ | SINE | Alu | Name=AluSx1 |
| ADediting_7155 | chr1_111461822_+ | SINE | Alu | Name=AluSx1 |
| ADediting_7156 | chr1_111461826_+ | SINE | Alu | Name=AluSx1 |
| ADediting_7157 | chr1_111461856_+ | SINE | Alu | Name=AluSx1 |
| ADediting_7158 | chr1_111461861_+ | SINE | Alu | Name=AluSx1 |
| ADediting_7159 | chr1_111461883_+ | SINE | Alu | Name=AluSx1 |
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RNA A-to-I editing events in the alternative splicing sites for ATP5PB |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ATP5PB |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for ATP5PB |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for ATP5PB |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_7140 | chr1_111461671_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-340-3p | chr1 | 111461665 | 111461671 | 7mer-m8 | 111461652 | 111461672 | 146 | -20.2 |
| ADediting_7140 | chr1_111461671_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-6827-3p | chr1 | 111461665 | 111461671 | 7mer-m8 | 111461653 | 111461672 | 151 | -19.6 |
| ADediting_7142 | chr1_111461700_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-3663-5p | chr1 | 111461698 | 111461704 | 7mer-m8 | 111461686 | 111461705 | 144 | -20.26 |
| ADediting_7142 | chr1_111461700_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-371a-5p | chr1 | 111461693 | 111461700 | 8mer-1a | 111461681 | 111461700 | 146 | -15.86 |
| ADediting_7142 | chr1_111461700_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-6843-3p | chr1 | 111461697 | 111461703 | 7mer-m8 | 111461685 | 111461704 | 152 | -20.48 |
| ADediting_7142 | chr1_111461700_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-6848-3p | chr1 | 111461697 | 111461703 | 7mer-m8 | 111461687 | 111461704 | 142 | -15.32 |
| ADediting_7143 | chr1_111461708_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-1538 | chr1 | 111461705 | 111461712 | 8mer-1a | 111461691 | 111461712 | 148 | -20.32 |
| ADediting_7143 | chr1_111461708_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-4745-3p | chr1 | 111461705 | 111461712 | 8mer-1a | 111461691 | 111461712 | 152 | -25.75 |
| ADediting_7144 | chr1_111461713_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-1234-3p | chr1 | 111461706 | 111461713 | 8mer-1a | 111461692 | 111461713 | 142 | -16.79 |
| ADediting_7144 | chr1_111461713_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-7107-5p | chr1 | 111461706 | 111461713 | 8mer-1a | 111461692 | 111461713 | 145 | -22.91 |
| ADediting_7145 | chr1_111461714_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-3176 | chr1 | 111461707 | 111461713 | 7mer-m8 | 111461696 | 111461714 | 150 | -20.56 |
| ADediting_7145 | chr1_111461714_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-3922-3p | chr1 | 111461707 | 111461713 | 7mer-m8 | 111461694 | 111461714 | 149 | -14.48 |
| ADediting_7145 | chr1_111461714_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-5008-3p | chr1 | 111461712 | 111461718 | 7mer-m8 | 111461699 | 111461719 | 148 | -20.17 |
| ADediting_7145 | chr1_111461714_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-6737-3p | chr1 | 111461712 | 111461718 | 7mer-m8 | 111461698 | 111461719 | 140 | -13.11 |
| ADediting_7145 | chr1_111461714_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-7157-3p | chr1 | 111461712 | 111461718 | 7mer-m8 | 111461696 | 111461719 | 151 | -19.82 |
| ADediting_7147 | chr1_111461747_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-1237-3p | chr1 | 111461744 | 111461750 | 7mer-m8 | 111461731 | 111461751 | 140 | -12.49 |
| ADediting_7147 | chr1_111461747_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-3182 | chr1 | 111461743 | 111461749 | 7mer-m8 | 111461733 | 111461750 | 150 | -14.77 |
| ADediting_7147 | chr1_111461747_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-4742-3p | chr1 | 111461740 | 111461747 | 8mer-1a | 111461725 | 111461747 | 142 | -10.99 |
| ADediting_7148 | chr1_111461748_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-643 | chr1 | 111461741 | 111461748 | 8mer-1a | 111461726 | 111461748 | 143 | -14.77 |
| ADediting_7150 | chr1_111461754_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-5189-3p | chr1 | 111461749 | 111461755 | 7mer-m8 | 111461736 | 111461756 | 142 | -11.58 |
| ADediting_7151 | chr1_111461781_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-8052 | chr1 | 111461779 | 111461785 | 7mer-1a | 111461765 | 111461785 | 145 | -22.32 |
| ADediting_7152 | chr1_111461790_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-1207-3p | chr1 | 111461783 | 111461789 | 7mer-m8 | 111461773 | 111461790 | 140 | -12.56 |
| ADediting_7152 | chr1_111461790_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-646 | chr1 | 111461785 | 111461791 | 7mer-m8 | 111461774 | 111461792 | 145 | -14.99 |
| ADediting_7153 | chr1_111461803_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-1913 | chr1 | 111461801 | 111461807 | 7mer-m8 | 111461789 | 111461808 | 148 | -25.01 |
| ADediting_7153 | chr1_111461803_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-6849-3p | chr1 | 111461796 | 111461802 | 7mer-m8 | 111461781 | 111461803 | 141 | -14.9 |
| ADediting_7155 | chr1_111461822_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-191-3p | chr1 | 111461820 | 111461826 | 7mer-m8 | 111461805 | 111461827 | 153 | -18.49 |
| ADediting_7156 | chr1_111461826_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-1471 | chr1 | 111461821 | 111461828 | 8mer-1a | 111461808 | 111461828 | 151 | -19.89 |
| ADediting_7157 | chr1_111461856_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-4634 | chr1 | 111461853 | 111461860 | 8mer-1a | 111461840 | 111461860 | 146 | -21.85 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_7140 | chr1_111461671_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-214-5p | chr1 | 111461667 | 111461673 | 7mer-m8 | 111461653 | 111461674 | 151 | -24.04 |
| ADediting_7140 | chr1_111461671_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-4421 | chr1 | 111461666 | 111461672 | 7mer-m8 | 111461653 | 111461673 | 142 | -16.68 |
| ADediting_7140 | chr1_111461671_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-4485-5p | chr1 | 111461669 | 111461676 | 8mer-1a | 111461661 | 111461676 | 142 | -15.86 |
| ADediting_7140 | chr1_111461671_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-5699-3p | chr1 | 111461666 | 111461672 | 7mer-m8 | 111461652 | 111461673 | 152 | -19.89 |
| ADediting_7142 | chr1_111461700_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-607 | chr1 | 111461694 | 111461700 | 7mer-1a | 111461679 | 111461700 | 143 | -14.77 |
| ADediting_7143 | chr1_111461708_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-3064-5p | chr1 | 111461702 | 111461708 | 7mer-m8 | 111461689 | 111461709 | 144 | -14.9 |
| ADediting_7143 | chr1_111461708_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-3085-3p | chr1 | 111461702 | 111461708 | 7mer-m8 | 111461688 | 111461709 | 146 | -17.05 |
| ADediting_7143 | chr1_111461708_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-6504-5p | chr1 | 111461702 | 111461708 | 7mer-m8 | 111461690 | 111461709 | 146 | -16.75 |
| ADediting_7146 | chr1_111461718_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-892a | chr1 | 111461713 | 111461719 | 7mer-m8 | 111461698 | 111461720 | 148 | -21.46 |
| ADediting_7151 | chr1_111461781_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-10399-5p | chr1 | 111461775 | 111461781 | 7mer-m8 | 111461763 | 111461782 | 145 | -12.94 |
| ADediting_7151 | chr1_111461781_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-5089-5p | chr1 | 111461779 | 111461785 | 7mer-m8 | 111461766 | 111461786 | 144 | -13.5 |
| ADediting_7151 | chr1_111461781_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-6504-3p | chr1 | 111461775 | 111461781 | 7mer-m8 | 111461761 | 111461782 | 148 | -14.15 |
| ADediting_7152 | chr1_111461790_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-6869-5p | chr1 | 111461787 | 111461793 | 7mer-m8 | 111461770 | 111461794 | 149 | -22.74 |
| ADediting_7154 | chr1_111461821_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-498-5p | chr1 | 111461815 | 111461821 | 7mer-m8 | 111461800 | 111461822 | 142 | -10.65 |
| ADediting_7155 | chr1_111461822_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-498-5p | chr1 | 111461815 | 111461821 | 7mer-m8 | 111461800 | 111461822 | 142 | -10.65 |
| ADediting_7156 | chr1_111461826_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-1976 | chr1 | 111461823 | 111461829 | 7mer-m8 | 111461811 | 111461830 | 144 | -18.68 |
| ADediting_7156 | chr1_111461826_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-3193 | chr1 | 111461821 | 111461828 | 8mer-1a | 111461807 | 111461828 | 142 | -18.54 |
| ADediting_7158 | chr1_111461861_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-5693 | chr1 | 111461857 | 111461863 | 7mer-m8 | 111461844 | 111461864 | 146 | -18.93 |
| ADediting_7159 | chr1_111461883_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-367-5p | chr1 | 111461877 | 111461884 | 8mer-1a | 111461863 | 111461884 | 143 | -12.17 |
| ADediting_7159 | chr1_111461883_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-7107-3p | chr1 | 111461880 | 111461886 | 7mer-m8 | 111461861 | 111461887 | 145 | -18.17 |
| ADediting_7159 | chr1_111461883_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-744-3p | chr1 | 111461876 | 111461882 | 7mer-m8 | 111461862 | 111461883 | 140 | -14.79 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337757 | chr7_5495852_- | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-589-3p | chr1 | 111461183 | 111461189 | 7mer-m8 | 111461167 | 111461190 | 145 | -12.61 |
| ADediting_1535951 | chr14_100874558_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-337-3p | chr1 | 111462328 | 111462334 | 7mer-m8 | 111462313 | 111462335 | 151 | -12.01 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-4775 | chr1 | 111461589 | 111461595 | 7mer-m8 | 111461571 | 111461596 | 150 | -12.44 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-5585-3p | chr1 | 111461427 | 111461433 | 7mer-m8 | 111461413 | 111461434 | 145 | -20.84 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-5688 | chr1 | 111461120 | 111461126 | 7mer-m8 | 111461106 | 111461127 | 140 | -9.4 |
| ADediting_291761 | chr11_93733708_- | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-1304-3p | chr1 | 111461133 | 111461139 | 7mer-1a | 111461117 | 111461139 | 142 | -20.34 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-4775 | chr1 | 111461386 | 111461393 | 8mer-1a | 111461372 | 111461393 | 145 | -8.1 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-4775 | chr1 | 111462052 | 111462059 | 8mer-1a | 111462038 | 111462059 | 147 | -12.2 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000116459.11 | ENST00000369722.8 | ATP5PB-202 | hsa-miR-4775 | chr1 | 111462108 | 111462115 | 8mer-1a | 111462094 | 111462115 | 150 | -5.64 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for ATP5PB |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000369722.8 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_7140 | ENST00000369722.8 | chr1_111461671_+ | 1526 | -701.70 | -702.40 | -724.80 |
| ADediting_7141 | ENST00000369722.8 | chr1_111461690_+ | 1545 | -702.80 | -702.40 | -724.80 |
| ADediting_7142 | ENST00000369722.8 | chr1_111461700_+ | 1555 | -702.80 | -702.40 | -724.80 |
| ADediting_7143 | ENST00000369722.8 | chr1_111461708_+ | 1563 | -703.10 | -702.40 | -724.80 |
| ADediting_7144 | ENST00000369722.8 | chr1_111461713_+ | 1568 | -703.70 | -702.40 | -724.80 |
| ADediting_7145 | ENST00000369722.8 | chr1_111461714_+ | 1569 | -702.80 | -702.40 | -724.80 |
| ADediting_7146 | ENST00000369722.8 | chr1_111461718_+ | 1573 | -702.10 | -702.40 | -724.80 |
| ADediting_7147 | ENST00000369722.8 | chr1_111461747_+ | 1602 | -702.80 | -702.40 | -724.80 |
| ADediting_7148 | ENST00000369722.8 | chr1_111461748_+ | 1603 | -704.50 | -702.40 | -724.80 |
| ADediting_7149 | ENST00000369722.8 | chr1_111461749_+ | 1604 | -703.40 | -702.40 | -724.80 |
| ADediting_7150 | ENST00000369722.8 | chr1_111461754_+ | 1609 | -707.80 | -702.40 | -724.80 |
| ADediting_7151 | ENST00000369722.8 | chr1_111461781_+ | 1636 | -704.10 | -702.40 | -724.80 |
| ADediting_7152 | ENST00000369722.8 | chr1_111461790_+ | 1645 | -702.70 | -702.40 | -724.80 |
| ADediting_7153 | ENST00000369722.8 | chr1_111461803_+ | 1658 | -704.20 | -702.40 | -724.80 |
| ADediting_7154 | ENST00000369722.8 | chr1_111461821_+ | 1676 | -703.60 | -702.40 | -724.80 |
| ADediting_7155 | ENST00000369722.8 | chr1_111461822_+ | 1677 | -703.00 | -702.40 | -724.80 |
| ADediting_7156 | ENST00000369722.8 | chr1_111461826_+ | 1681 | -703.90 | -702.40 | -724.80 |
| ADediting_7157 | ENST00000369722.8 | chr1_111461856_+ | 1711 | -701.70 | -702.40 | -724.80 |
| ADediting_7158 | ENST00000369722.8 | chr1_111461861_+ | 1716 | -702.00 | -702.40 | -724.80 |
| ADediting_7159 | ENST00000369722.8 | chr1_111461883_+ | 1738 | -703.70 | -702.40 | -724.80 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for ATP5PB |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_7141 | chr1_111461690_+ | 0.00786379561984078 | 0.216248571845894 | 8.95202288289602e-06 | 0.35377312912061 | 0.553550945620489 | 0.0487521956079941 |
| CER | ADediting_7143 | chr1_111461708_+ | 0.00126683564840413 | 0.260800250043285 | 7.02692008545044e-06 | 0.357626535446972 | 0.88754197541291 | -0.0116435120118899 |
| CER | ADediting_7145 | chr1_111461714_+ | 3.39934500815299e-09 | 0.459243119677246 | 1.77862443580375e-08 | 0.439887434420344 | 0.22404631031872 | 0.0998598544130573 |
| CER | ADediting_7146 | chr1_111461718_+ | 1.62406572293897e-09 | 0.467508059305269 | 1.48148157997579e-11 | 0.515464384096203 | 0.678323793009034 | 0.0341400440091386 |
| CER | ADediting_7150 | chr1_111461754_+ | 0.000368525358480139 | 0.287064057215256 | 6.38677513698495e-05 | 0.320467870011531 | 0.0327506261237832 | 0.174452663619921 |
| CER | ADediting_7156 | chr1_111461826_+ | 0.000337964209053054 | 0.288812284873292 | 4.66046247310432e-06 | 0.364049252559448 | 0.877384584686827 | 0.0127031224343774 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 1.43555591538179e-62 | 0.771988713881456 | 2.6896740821117e-50 | 0.717507159756184 | 0.199849129453508 | 0.0730093921651714 |
| AC | 9.14991764347252e-79 | 0.871647221993222 | 4.95087096535563e-49 | 0.763657583216401 | 5.36287343829559e-17 | 0.496934815460481 |
| PCC | 4.45738812436983e-33 | 0.730062017535328 | 5.90178255008126e-33 | 0.729114293577123 | 0.0248346251104725 | 0.162354603772626 |
| CER | 1.29979549882824e-16 | 0.609302326052746 | 1.04124116991303e-05 | 0.351342409298808 | 0.0200494109105806 | 0.189729121196073 |
| TCX | 4.53667571933485e-31 | 0.773157914203876 | 1.0437719915113e-14 | 0.577344339880713 | 0.896865601020802 | 0.0106725609509171 |
| FP | 6.33806129685871e-11 | 0.464774195724138 | 8.04844169648824e-18 | 0.586335195596312 | 0.134583323502693 | -0.11258649020508 |
| IFG | 0.0115747648951846 | 0.496550857909543 | 0.105599708076163 | 0.331402886707886 | 0.152154806932063 | -0.295076368369276 |
| PG | 1.08664782428677e-47 | 0.826016293436668 | 1.59408560711039e-23 | 0.647929637483682 | 0.189641120782443 | -0.0966003542570206 |
| STG | 5.1662004344117e-18 | 0.774920697050978 | 6.75684559143077e-15 | 0.724455183515619 | 0.570422044327209 | -0.0627914065052321 |
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Relation with AD stages for ATP5PB |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| STG | 0.00296539768758015 | -0.32040368615366 |
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RelatedDrugs for ATP5PB |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ATP5PB |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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