|
||||||
|
 | |
| |
| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
| |
| |
| The effects of the RNA editing to the stability of the RNA structures |
| |
| |
| |
|
Gene summary for MRPS17 |
 Gene summary |
| Gene information | Gene symbol | MRPS17 | Gene ID | 51373 |
| Gene name | mitochondrial ribosomal protein S17 | |
| Synonyms | HSPC011|MRP-S17|RPMS17|S17mt | |
| Cytomap | 7p11.2 | |
| Type of gene | protein-coding | |
| Description | 28S ribosomal protein S17, mitochondrialmitochondrial small ribosomal subunit protein uS17m | |
| Modification date | 20200313 | |
| UniProtAcc | Q9Y2R5, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
RNA A-to-I events for MRPS17 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_1339142(55952579, +), ADediting_1339143(55952614, +), ADediting_1339144(55952676, +), ADediting_1339145(55955465, +), ADediting_1339146(55955498, +), ADediting_1339147(55955514, +), ADediting_1339148(55955563, +), ADediting_1339149(55956192, +), ADediting_1339150(55956200, +), ADediting_1339151(55956216, +), ADediting_1339152(55956223, +), ADediting_1339153(55956253, +), ADediting_1339154(55956259, +), ADediting_1339155(55956261, +), ADediting_1339156(55956299, +), ADediting_1339157(55956302, +), ADediting_1339158(55956319, +), ADediting_1339159(55956333, +), ADediting_1339160(55956380, +), ADediting_1339161(55956381, +), ADediting_1587826(55956179, +), ADediting_1587827(55956237, +), ADediting_1587828(55956249, +), ADediting_1587829(55956281, +), ADediting_1587830(55956353, +), |
Top |
RNA editing positional annotations for MRPS17 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_1339142 | chr7_55952579_+ | intronic |
| ADediting_1339143 | chr7_55952614_+ | intronic |
| ADediting_1339144 | chr7_55952676_+ | intronic |
| ADediting_1339145 | chr7_55955465_+ | UTR3 |
| ADediting_1339146 | chr7_55955498_+ | UTR3 |
| ADediting_1339147 | chr7_55955514_+ | UTR3 |
| ADediting_1339148 | chr7_55955563_+ | UTR3 |
| ADediting_1339149 | chr7_55956192_+ | UTR3 |
| ADediting_1339150 | chr7_55956200_+ | UTR3 |
| ADediting_1339151 | chr7_55956216_+ | UTR3 |
| ADediting_1339152 | chr7_55956223_+ | UTR3 |
| ADediting_1339153 | chr7_55956253_+ | UTR3 |
| ADediting_1339154 | chr7_55956259_+ | UTR3 |
| ADediting_1339155 | chr7_55956261_+ | UTR3 |
| ADediting_1339156 | chr7_55956299_+ | UTR3 |
| ADediting_1339157 | chr7_55956302_+ | UTR3 |
| ADediting_1339158 | chr7_55956319_+ | UTR3 |
| ADediting_1339159 | chr7_55956333_+ | UTR3 |
| ADediting_1339160 | chr7_55956380_+ | UTR3 |
| ADediting_1339161 | chr7_55956381_+ | UTR3 |
| ADediting_1587826 | chr7_55956179_+ | UTR3 |
| ADediting_1587827 | chr7_55956237_+ | UTR3 |
| ADediting_1587828 | chr7_55956249_+ | UTR3 |
| ADediting_1587829 | chr7_55956281_+ | UTR3 |
| ADediting_1587830 | chr7_55956353_+ | UTR3 |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_1339142 | chr7_55952579_+ | SINE | Alu | Name=AluSx |
| ADediting_1339143 | chr7_55952614_+ | SINE | Alu | Name=AluSx |
| ADediting_1339144 | chr7_55952676_+ | SINE | Alu | Name=AluSx |
| ADediting_1339145 | chr7_55955465_+ | SINE | Alu | Name=AluY |
| ADediting_1339146 | chr7_55955498_+ | SINE | Alu | Name=AluY |
| ADediting_1339147 | chr7_55955514_+ | SINE | Alu | Name=AluY |
| ADediting_1339148 | chr7_55955563_+ | SINE | Alu | Name=AluY |
| ADediting_1339149 | chr7_55956192_+ | SINE | Alu | Name=AluSp |
| ADediting_1339150 | chr7_55956200_+ | SINE | Alu | Name=AluSp |
| ADediting_1339151 | chr7_55956216_+ | SINE | Alu | Name=AluSp |
| ADediting_1339152 | chr7_55956223_+ | SINE | Alu | Name=AluSp |
| ADediting_1339153 | chr7_55956253_+ | SINE | Alu | Name=AluSp |
| ADediting_1339154 | chr7_55956259_+ | SINE | Alu | Name=AluSp |
| ADediting_1339155 | chr7_55956261_+ | SINE | Alu | Name=AluSp |
| ADediting_1339156 | chr7_55956299_+ | SINE | Alu | Name=AluSp |
| ADediting_1339157 | chr7_55956302_+ | SINE | Alu | Name=AluSp |
| ADediting_1339158 | chr7_55956319_+ | SINE | Alu | Name=AluSp |
| ADediting_1339159 | chr7_55956333_+ | SINE | Alu | Name=AluSp |
| ADediting_1339160 | chr7_55956380_+ | SINE | Alu | Name=AluSp |
| ADediting_1339161 | chr7_55956381_+ | SINE | Alu | Name=AluSp |
| ADediting_1587826 | chr7_55956179_+ | SINE | Alu | Name=AluSp |
| ADediting_1587827 | chr7_55956237_+ | SINE | Alu | Name=AluSp |
| ADediting_1587828 | chr7_55956249_+ | SINE | Alu | Name=AluSp |
| ADediting_1587829 | chr7_55956281_+ | SINE | Alu | Name=AluSp |
| ADediting_1587830 | chr7_55956353_+ | SINE | Alu | Name=AluSp |
Top |
RNA A-to-I editing events in the alternative splicing sites for MRPS17 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for MRPS17 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for MRPS17 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for MRPS17 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1339146 | chr7_55955498_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-3130-3p | chr7 | 55955491 | 55955497 | 7mer-m8 | 55955477 | 55955498 | 146 | -18.52 |
| ADediting_1339147 | chr7_55955514_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-17-3p | chr7 | 55955507 | 55955513 | 7mer-m8 | 55955494 | 55955514 | 153 | -18.97 |
| ADediting_1339147 | chr7_55955514_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-596 | chr7 | 55955510 | 55955516 | 7mer-m8 | 55955497 | 55955517 | 140 | -17.7 |
| ADediting_1339148 | chr7_55955563_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-4691-3p | chr7 | 55955560 | 55955566 | 7mer-m8 | 55955540 | 55955567 | 150 | -26.36 |
| ADediting_1339149 | chr7_55956192_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-6877-5p | chr7 | 55956189 | 55956196 | 8mer-1a | 55956174 | 55956196 | 141 | -18.96 |
| ADediting_1339150 | chr7_55956200_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-6786-5p | chr7 | 55956193 | 55956199 | 7mer-m8 | 55956182 | 55956200 | 145 | -26.19 |
| ADediting_1339151 | chr7_55956216_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-1247-3p | chr7 | 55956211 | 55956217 | 7mer-m8 | 55956196 | 55956218 | 146 | -23.6 |
| ADediting_1339152 | chr7_55956223_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-3622a-3p | chr7 | 55956219 | 55956226 | 8mer-1a | 55956204 | 55956226 | 149 | -18.21 |
| ADediting_1339152 | chr7_55956223_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-3622b-3p | chr7 | 55956219 | 55956226 | 8mer-1a | 55956206 | 55956226 | 147 | -18.77 |
| ADediting_1339153 | chr7_55956253_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-5690 | chr7 | 55956246 | 55956252 | 7mer-m8 | 55956233 | 55956253 | 145 | -17.72 |
| ADediting_1339153 | chr7_55956253_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-7977 | chr7 | 55956249 | 55956255 | 7mer-m8 | 55956240 | 55956256 | 145 | -13.47 |
| ADediting_1339157 | chr7_55956302_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-4286 | chr7 | 55956298 | 55956305 | 8mer-1a | 55956289 | 55956305 | 143 | -17.17 |
| ADediting_1339157 | chr7_55956302_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-4301 | chr7 | 55956297 | 55956303 | 7mer-m8 | 55956285 | 55956304 | 140 | -12.73 |
| ADediting_1339159 | chr7_55956333_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-6849-3p | chr7 | 55956327 | 55956333 | 7mer-m8 | 55956313 | 55956334 | 145 | -17.87 |
| ADediting_1339160 | chr7_55956380_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-3921 | chr7 | 55956375 | 55956381 | 7mer-m8 | 55956360 | 55956382 | 146 | -19.12 |
| ADediting_1339160 | chr7_55956380_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-4653-5p | chr7 | 55956375 | 55956381 | 7mer-m8 | 55956363 | 55956382 | 154 | -20.06 |
| ADediting_1339160 | chr7_55956380_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-4714-5p | chr7 | 55956376 | 55956382 | 7mer-m8 | 55956361 | 55956383 | 147 | -17.55 |
| ADediting_1339160 | chr7_55956380_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-6761-5p | chr7 | 55956373 | 55956380 | 8mer-1a | 55956360 | 55956380 | 151 | -25.84 |
| ADediting_1587826 | chr7_55956179_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-324-3p | chr7 | 55956175 | 55956181 | 7mer-m8 | 55956160 | 55956182 | 148 | -24.15 |
| ADediting_1587826 | chr7_55956179_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-4252 | chr7 | 55956176 | 55956183 | 8mer-1a | 55956163 | 55956183 | 149 | -22.82 |
| ADediting_1587826 | chr7_55956179_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-4793-3p | chr7 | 55956172 | 55956178 | 7mer-m8 | 55956157 | 55956179 | 149 | -19.36 |
| ADediting_1587827 | chr7_55956237_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-6089 | chr7 | 55956235 | 55956241 | 7mer-m8 | 55956219 | 55956242 | 156 | -29.55 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1339145 | chr7_55955465_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-5586-3p | chr7 | 55955462 | 55955468 | 7mer-m8 | 55955448 | 55955469 | 148 | -14.42 |
| ADediting_1339145 | chr7_55955465_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-759 | chr7 | 55955463 | 55955469 | 7mer-m8 | 55955448 | 55955470 | 147 | -12.87 |
| ADediting_1339146 | chr7_55955498_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-25-3p | chr7 | 55955492 | 55955498 | 7mer-m8 | 55955474 | 55955499 | 153 | -24.46 |
| ADediting_1339146 | chr7_55955498_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-32-5p | chr7 | 55955492 | 55955498 | 7mer-m8 | 55955477 | 55955499 | 144 | -12.85 |
| ADediting_1339146 | chr7_55955498_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-363-3p | chr7 | 55955492 | 55955498 | 7mer-m8 | 55955473 | 55955499 | 149 | -19.28 |
| ADediting_1339146 | chr7_55955498_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-367-3p | chr7 | 55955492 | 55955498 | 7mer-m8 | 55955478 | 55955499 | 153 | -17.21 |
| ADediting_1339146 | chr7_55955498_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-92b-3p | chr7 | 55955492 | 55955498 | 7mer-m8 | 55955474 | 55955499 | 155 | -23.12 |
| ADediting_1339147 | chr7_55955514_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-4327 | chr7 | 55955509 | 55955515 | 7mer-m8 | 55955497 | 55955516 | 147 | -15.99 |
| ADediting_1339147 | chr7_55955514_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-6516-5p | chr7 | 55955507 | 55955513 | 7mer-m8 | 55955491 | 55955514 | 149 | -16.17 |
| ADediting_1339148 | chr7_55955563_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-5690 | chr7 | 55955560 | 55955566 | 7mer-m8 | 55955547 | 55955567 | 145 | -16.75 |
| ADediting_1339149 | chr7_55956192_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-1587 | chr7 | 55956190 | 55956196 | 7mer-m8 | 55956178 | 55956197 | 148 | -17.14 |
| ADediting_1339149 | chr7_55956192_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-3620-5p | chr7 | 55956190 | 55956196 | 7mer-m8 | 55956175 | 55956197 | 149 | -23.45 |
| ADediting_1339149 | chr7_55956192_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-4656 | chr7 | 55956189 | 55956196 | 8mer-1a | 55956174 | 55956196 | 155 | -26.46 |
| ADediting_1339150 | chr7_55956200_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-4440 | chr7 | 55956197 | 55956203 | 7mer-m8 | 55956182 | 55956204 | 149 | -21.27 |
| ADediting_1339151 | chr7_55956216_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-1273h-5p | chr7 | 55956209 | 55956215 | 7mer-m8 | 55956196 | 55956216 | 153 | -25.85 |
| ADediting_1339151 | chr7_55956216_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-490-3p | chr7 | 55956213 | 55956219 | 7mer-m8 | 55956198 | 55956220 | 146 | -16.49 |
| ADediting_1339151 | chr7_55956216_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-6779-5p | chr7 | 55956209 | 55956215 | 7mer-m8 | 55956196 | 55956216 | 151 | -30.58 |
| ADediting_1339151 | chr7_55956216_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-6780a-5p | chr7 | 55956209 | 55956215 | 7mer-m8 | 55956191 | 55956216 | 146 | -21.45 |
| ADediting_1339152 | chr7_55956223_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-3614-5p | chr7 | 55956220 | 55956226 | 7mer-1a | 55956203 | 55956226 | 155 | -24.76 |
| ADediting_1339153 | chr7_55956253_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-500a-5p | chr7 | 55956252 | 55956258 | 7mer-1a | 55956236 | 55956258 | 144 | -23.28 |
| ADediting_1339155 | chr7_55956261_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-6514-3p | chr7 | 55956258 | 55956264 | 7mer-m8 | 55956241 | 55956265 | 152 | -18.22 |
| ADediting_1339158 | chr7_55956319_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-4531 | chr7 | 55956312 | 55956318 | 7mer-m8 | 55956303 | 55956319 | 147 | -15.25 |
| ADediting_1587826 | chr7_55956179_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-32-5p | chr7 | 55956173 | 55956179 | 7mer-m8 | 55956159 | 55956180 | 144 | -12.53 |
| ADediting_1587826 | chr7_55956179_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-363-3p | chr7 | 55956173 | 55956179 | 7mer-m8 | 55956159 | 55956180 | 147 | -16.12 |
| ADediting_1587826 | chr7_55956179_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-92a-3p | chr7 | 55956173 | 55956179 | 7mer-m8 | 55956163 | 55956180 | 155 | -26.92 |
| ADediting_1587827 | chr7_55956237_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-3929 | chr7 | 55956234 | 55956240 | 7mer-m8 | 55956218 | 55956241 | 150 | -24.72 |
| ADediting_1587827 | chr7_55956237_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-4478 | chr7 | 55956234 | 55956240 | 7mer-m8 | 55956224 | 55956241 | 149 | -20.76 |
| ADediting_1587827 | chr7_55956237_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-485-5p | chr7 | 55956235 | 55956241 | 7mer-m8 | 55956220 | 55956242 | 147 | -15.93 |
| ADediting_1587827 | chr7_55956237_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-6884-5p | chr7 | 55956235 | 55956241 | 7mer-m8 | 55956219 | 55956242 | 150 | -19.35 |
| ADediting_1587829 | chr7_55956281_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-4486 | chr7 | 55956275 | 55956281 | 7mer-m8 | 55956267 | 55956282 | 153 | -28.71 |
| ADediting_1587830 | chr7_55956353_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-3622a-3p | chr7 | 55956350 | 55956357 | 8mer-1a | 55956336 | 55956357 | 149 | -17.25 |
| ADediting_1587830 | chr7_55956353_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-7162-3p | chr7 | 55956347 | 55956353 | 7mer-m8 | 55956334 | 55956354 | 142 | -17.7 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000239789.6 | ENST00000285298.9 | MRPS17-201 | hsa-miR-5688 | chr7 | 55956320 | 55956327 | 8mer-1a | 55956307 | 55956327 | 155 | -16.32 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| Differentially expressed gene-miRNA network |
Top |
The effects of the RNA editing to the stability of the RNA structures for MRPS17 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000285298.9 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_1339145 | ENST00000285298.9 | chr7_55955465_+ | 751 | -585.80 | -586.30 | -611.00 |
| ADediting_1339146 | ENST00000285298.9 | chr7_55955498_+ | 784 | -586.30 | -586.30 | -611.00 |
| ADediting_1339147 | ENST00000285298.9 | chr7_55955514_+ | 800 | -586.30 | -586.30 | -611.00 |
| ADediting_1339148 | ENST00000285298.9 | chr7_55955563_+ | 849 | -588.00 | -586.30 | -611.00 |
| ADediting_1587826 | ENST00000285298.9 | chr7_55956179_+ | 1465 | -591.90 | -586.30 | -611.00 |
| ADediting_1339149 | ENST00000285298.9 | chr7_55956192_+ | 1478 | -590.70 | -586.30 | -611.00 |
| ADediting_1339150 | ENST00000285298.9 | chr7_55956200_+ | 1486 | -588.20 | -586.30 | -611.00 |
| ADediting_1339151 | ENST00000285298.9 | chr7_55956216_+ | 1502 | -589.80 | -586.30 | -611.00 |
| ADediting_1339152 | ENST00000285298.9 | chr7_55956223_+ | 1509 | -588.20 | -586.30 | -611.00 |
| ADediting_1587827 | ENST00000285298.9 | chr7_55956237_+ | 1523 | -585.70 | -586.30 | -611.00 |
| ADediting_1587828 | ENST00000285298.9 | chr7_55956249_+ | 1535 | -586.80 | -586.30 | -611.00 |
| ADediting_1339153 | ENST00000285298.9 | chr7_55956253_+ | 1539 | -587.00 | -586.30 | -611.00 |
| ADediting_1339154 | ENST00000285298.9 | chr7_55956259_+ | 1545 | -585.90 | -586.30 | -611.00 |
| ADediting_1339155 | ENST00000285298.9 | chr7_55956261_+ | 1547 | -586.20 | -586.30 | -611.00 |
| ADediting_1587829 | ENST00000285298.9 | chr7_55956281_+ | 1567 | -587.30 | -586.30 | -611.00 |
| ADediting_1339156 | ENST00000285298.9 | chr7_55956299_+ | 1585 | -586.00 | -586.30 | -611.00 |
| ADediting_1339157 | ENST00000285298.9 | chr7_55956302_+ | 1588 | -588.60 | -586.30 | -611.00 |
| ADediting_1339158 | ENST00000285298.9 | chr7_55956319_+ | 1605 | -585.90 | -586.30 | -611.00 |
| ADediting_1339159 | ENST00000285298.9 | chr7_55956333_+ | 1619 | -589.50 | -586.30 | -611.00 |
| ADediting_1587830 | ENST00000285298.9 | chr7_55956353_+ | 1639 | -586.80 | -586.30 | -611.00 |
| ADediting_1339160 | ENST00000285298.9 | chr7_55956380_+ | 1666 | -588.30 | -586.30 | -611.00 |
| ADediting_1339161 | ENST00000285298.9 | chr7_55956381_+ | 1667 | -589.80 | -586.30 | -611.00 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
Top |
Relation with ADAR for MRPS17 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 3.84501372587586e-44 | 0.684256422443547 | 9.66100166522397e-31 | 0.592312190866603 | 1.15624206606675e-22 | 0.517804059949538 |
| AC | 5.78312379042193e-84 | 0.884224460387505 | 2.00764032453897e-68 | 0.842015892612659 | 9.35813482655408e-09 | 0.353155094823795 |
| PCC | 1.0756501106807e-33 | 0.73480110220257 | 1.41868899656859e-38 | 0.768970169765552 | 0.149713206918534 | 0.104634705622327 |
| CER | 1.12325242758598e-07 | 0.416805015846703 | 3.60344694684362e-06 | 0.368003044888072 | 0.160849818851695 | -0.115072650778271 |
| TCX | 5.93433240125346e-20 | 0.657839783369221 | 5.02583007691489e-30 | 0.7645571074008 | 0.00215561070758229 | -0.2486281961948 |
| FP | 1.07654183702457e-13 | 0.519559085578682 | 8.94034317947271e-26 | 0.682783217083832 | 0.824046874149018 | -0.0167823756501582 |
| IFG | 0.00537310331315879 | 0.539584430976877 | 0.0271749638680355 | 0.441424398070638 | 0.0671765244984808 | -0.371880284265162 |
| PG | 1.78274641159296e-41 | 0.793092630591841 | 1.51746052231107e-28 | 0.69851554271425 | 0.110300359676506 | -0.11747248040141 |
| STG | 5.7202636282604e-16 | 0.74319535746299 | 1.04880053337451e-14 | 0.720948467300134 | 0.698022162454893 | -0.0429574852748654 |
Top |
Relation with AD stages for MRPS17 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
Top |
RelatedDrugs for MRPS17 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for MRPS17 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|