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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for RRNAD1 |
 Gene summary |
| Gene information | Gene symbol | RRNAD1 | Gene ID | 51093 |
| Gene name | ribosomal RNA adenine dimethylase domain containing 1 | |
| Synonyms | C1orf66|CGI-41|METTL25B | |
| Cytomap | 1q23.1 | |
| Type of gene | protein-coding | |
| Description | protein RRNAD1ribosomal RNA adenine dimethylase domain-containing protein 1 | |
| Modification date | 20200313 | |
| UniProtAcc | Q96FB5, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
RNA A-to-I events for RRNAD1 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_35419(156729488, +), ADediting_35420(156730462, +), ADediting_35421(156730469, +), ADediting_35422(156730528, +), ADediting_35423(156730538, +), ADediting_35424(156730540, +), ADediting_35425(156730605, +), ADediting_35426(156730621, +), ADediting_35427(156730650, +), ADediting_35428(156730652, +), ADediting_35429(156730653, +), ADediting_35430(156730682, +), ADediting_35431(156730707, +), ADediting_35432(156731167, +), ADediting_35433(156731185, +), ADediting_35434(156731187, +), ADediting_35435(156731188, +), ADediting_35436(156731192, +), ADediting_35437(156731224, +), ADediting_35438(156731241, +), ADediting_35439(156731253, +), ADediting_35440(156731276, +), ADediting_35441(156731304, +), ADediting_35442(156731324, +), ADediting_35443(156731326, +), ADediting_35444(156731333, +), ADediting_35445(156731358, +), ADediting_35446(156731385, +), ADediting_35447(156731386, +), ADediting_35448(156731398, +), ADediting_35449(156734112, +), ADediting_35450(156734587, +), ADediting_35451(156734606, +), ADediting_35452(156734611, +), ADediting_35453(156734612, +), ADediting_35454(156734631, +), ADediting_35455(156734642, +), ADediting_35456(156734649, +), ADediting_35457(156734661, +), ADediting_35458(156734671, +), ADediting_35459(156734698, +), ADediting_35460(156734713, +), ADediting_35461(156734716, +), ADediting_35462(156734718, +), ADediting_35463(156734738, +), ADediting_35464(156734742, +), ADediting_35465(156734753, +), ADediting_35466(156734792, +), ADediting_35467(156734793, +), ADediting_35468(156734805, +), ADediting_35469(156734807, +), ADediting_35470(156734823, +), ADediting_35471(156734894, +), ADediting_35472(156735011, +), ADediting_35473(156735025, +), ADediting_35474(156735033, +), ADediting_35475(156735034, +), ADediting_35476(156735039, +), ADediting_35477(156735050, +), ADediting_35478(156735079, +), ADediting_35479(156735102, +), ADediting_35480(156735103, +), ADediting_35481(156735105, +), ADediting_35482(156735113, +), ADediting_35483(156735124, +), ADediting_35484(156735127, +), ADediting_35485(156735128, +), ADediting_35486(156735129, +), ADediting_35487(156735130, +), ADediting_35488(156735133, +), ADediting_35489(156735142, +), ADediting_35490(156735146, +), ADediting_35491(156735158, +), ADediting_35492(156735168, +), ADediting_35493(156735169, +), ADediting_35494(156735191, +), ADediting_35495(156735199, +), ADediting_35496(156735210, +), ADediting_35497(156735223, +), ADediting_35498(156735230, +), ADediting_35499(156735234, +), ADediting_35500(156735235, +), ADediting_35501(156735239, +), ADediting_35502(156735241, +), ADediting_35503(156735422, +), ADediting_35504(156735444, +), ADediting_35505(156735445, +), ADediting_35506(156735466, +), ADediting_35507(156736126, +), ADediting_35508(156736267, +), ADediting_1515845(156730460, +), ADediting_1515846(156730509, +), ADediting_1515847(156730589, +), ADediting_1515848(156730673, +), ADediting_1515849(156731263, +), ADediting_1515850(156735277, +), ADediting_1515851(156736221, +), |
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RNA editing positional annotations for RRNAD1 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| ADediting_35449 | chr1_156734112_+ | nonsynonymous SNV | ENST00000368216.9 | c.A740G | p.Q247R | 0.266 | 0.002 | -1.23 |
| ADediting_35449 | chr1_156734112_+ | nonsynonymous SNV | ENST00000519086.5 | c.A677G | p.Q226R | 0.266 | 0.002 | -1.23 |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_35419 | chr1_156729488_+ | intronic |
| ADediting_35420 | chr1_156730462_+ | intronic |
| ADediting_35421 | chr1_156730469_+ | intronic |
| ADediting_35422 | chr1_156730528_+ | intronic |
| ADediting_35423 | chr1_156730538_+ | intronic |
| ADediting_35424 | chr1_156730540_+ | intronic |
| ADediting_35425 | chr1_156730605_+ | intronic |
| ADediting_35426 | chr1_156730621_+ | intronic |
| ADediting_35427 | chr1_156730650_+ | intronic |
| ADediting_35428 | chr1_156730652_+ | intronic |
| ADediting_35429 | chr1_156730653_+ | intronic |
| ADediting_35430 | chr1_156730682_+ | intronic |
| ADediting_35431 | chr1_156730707_+ | intronic |
| ADediting_35432 | chr1_156731167_+ | intronic |
| ADediting_35433 | chr1_156731185_+ | intronic |
| ADediting_35434 | chr1_156731187_+ | intronic |
| ADediting_35435 | chr1_156731188_+ | intronic |
| ADediting_35436 | chr1_156731192_+ | intronic |
| ADediting_35437 | chr1_156731224_+ | intronic |
| ADediting_35438 | chr1_156731241_+ | intronic |
| ADediting_35439 | chr1_156731253_+ | intronic |
| ADediting_35440 | chr1_156731276_+ | intronic |
| ADediting_35441 | chr1_156731304_+ | intronic |
| ADediting_35442 | chr1_156731324_+ | intronic |
| ADediting_35443 | chr1_156731326_+ | intronic |
| ADediting_35444 | chr1_156731333_+ | intronic |
| ADediting_35445 | chr1_156731358_+ | intronic |
| ADediting_35446 | chr1_156731385_+ | intronic |
| ADediting_35447 | chr1_156731386_+ | intronic |
| ADediting_35448 | chr1_156731398_+ | intronic |
| ADediting_35449 | chr1_156734112_+ | exonic |
| ADediting_35450 | chr1_156734587_+ | intronic |
| ADediting_35451 | chr1_156734606_+ | intronic |
| ADediting_35452 | chr1_156734611_+ | intronic |
| ADediting_35453 | chr1_156734612_+ | intronic |
| ADediting_35454 | chr1_156734631_+ | intronic |
| ADediting_35455 | chr1_156734642_+ | intronic |
| ADediting_35456 | chr1_156734649_+ | intronic |
| ADediting_35457 | chr1_156734661_+ | intronic |
| ADediting_35458 | chr1_156734671_+ | intronic |
| ADediting_35459 | chr1_156734698_+ | intronic |
| ADediting_35460 | chr1_156734713_+ | intronic |
| ADediting_35461 | chr1_156734716_+ | intronic |
| ADediting_35462 | chr1_156734718_+ | intronic |
| ADediting_35463 | chr1_156734738_+ | intronic |
| ADediting_35464 | chr1_156734742_+ | intronic |
| ADediting_35465 | chr1_156734753_+ | intronic |
| ADediting_35466 | chr1_156734792_+ | intronic |
| ADediting_35467 | chr1_156734793_+ | intronic |
| ADediting_35468 | chr1_156734805_+ | intronic |
| ADediting_35469 | chr1_156734807_+ | intronic |
| ADediting_35470 | chr1_156734823_+ | intronic |
| ADediting_35471 | chr1_156734894_+ | intronic |
| ADediting_35472 | chr1_156735011_+ | intronic |
| ADediting_35473 | chr1_156735025_+ | intronic |
| ADediting_35474 | chr1_156735033_+ | intronic |
| ADediting_35475 | chr1_156735034_+ | intronic |
| ADediting_35476 | chr1_156735039_+ | intronic |
| ADediting_35477 | chr1_156735050_+ | intronic |
| ADediting_35478 | chr1_156735079_+ | intronic |
| ADediting_35479 | chr1_156735102_+ | intronic |
| ADediting_35480 | chr1_156735103_+ | intronic |
| ADediting_35481 | chr1_156735105_+ | intronic |
| ADediting_35482 | chr1_156735113_+ | intronic |
| ADediting_35483 | chr1_156735124_+ | intronic |
| ADediting_35484 | chr1_156735127_+ | intronic |
| ADediting_35485 | chr1_156735128_+ | intronic |
| ADediting_35486 | chr1_156735129_+ | intronic |
| ADediting_35487 | chr1_156735130_+ | intronic |
| ADediting_35488 | chr1_156735133_+ | intronic |
| ADediting_35489 | chr1_156735142_+ | intronic |
| ADediting_35490 | chr1_156735146_+ | intronic |
| ADediting_35491 | chr1_156735158_+ | intronic |
| ADediting_35492 | chr1_156735168_+ | intronic |
| ADediting_35493 | chr1_156735169_+ | intronic |
| ADediting_35494 | chr1_156735191_+ | intronic |
| ADediting_35495 | chr1_156735199_+ | intronic |
| ADediting_35496 | chr1_156735210_+ | intronic |
| ADediting_35497 | chr1_156735223_+ | intronic |
| ADediting_35498 | chr1_156735230_+ | intronic |
| ADediting_35499 | chr1_156735234_+ | intronic |
| ADediting_35500 | chr1_156735235_+ | intronic |
| ADediting_35501 | chr1_156735239_+ | intronic |
| ADediting_35502 | chr1_156735241_+ | intronic |
| ADediting_35503 | chr1_156735422_+ | intronic |
| ADediting_35504 | chr1_156735444_+ | intronic |
| ADediting_35505 | chr1_156735445_+ | intronic |
| ADediting_35506 | chr1_156735466_+ | intronic |
| ADediting_35507 | chr1_156736126_+ | intronic |
| ADediting_35508 | chr1_156736267_+ | intronic |
| ADediting_1515845 | chr1_156730460_+ | intronic |
| ADediting_1515846 | chr1_156730509_+ | intronic |
| ADediting_1515847 | chr1_156730589_+ | intronic |
| ADediting_1515848 | chr1_156730673_+ | intronic |
| ADediting_1515849 | chr1_156731263_+ | intronic |
| ADediting_1515850 | chr1_156735277_+ | intronic |
| ADediting_1515851 | chr1_156736221_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_35419 | chr1_156729488_+ | SINE | Alu | Name=AluYj4 |
| ADediting_35420 | chr1_156730462_+ | SINE | Alu | Name=AluSx |
| ADediting_35421 | chr1_156730469_+ | SINE | Alu | Name=AluSx |
| ADediting_35422 | chr1_156730528_+ | SINE | Alu | Name=AluSx |
| ADediting_35423 | chr1_156730538_+ | SINE | Alu | Name=AluSx |
| ADediting_35424 | chr1_156730540_+ | SINE | Alu | Name=AluSx |
| ADediting_35425 | chr1_156730605_+ | SINE | Alu | Name=AluSx |
| ADediting_35426 | chr1_156730621_+ | SINE | Alu | Name=AluSx |
| ADediting_35427 | chr1_156730650_+ | SINE | Alu | Name=AluSx |
| ADediting_35428 | chr1_156730652_+ | SINE | Alu | Name=AluSx |
| ADediting_35429 | chr1_156730653_+ | SINE | Alu | Name=AluSx |
| ADediting_35430 | chr1_156730682_+ | SINE | Alu | Name=AluSx |
| ADediting_35431 | chr1_156730707_+ | SINE | Alu | Name=AluSx |
| ADediting_35432 | chr1_156731167_+ | SINE | Alu | Name=AluSx |
| ADediting_35433 | chr1_156731185_+ | SINE | Alu | Name=AluSx |
| ADediting_35434 | chr1_156731187_+ | SINE | Alu | Name=AluSx |
| ADediting_35435 | chr1_156731188_+ | SINE | Alu | Name=AluSx |
| ADediting_35436 | chr1_156731192_+ | SINE | Alu | Name=AluSx |
| ADediting_35437 | chr1_156731224_+ | SINE | Alu | Name=AluSx |
| ADediting_35438 | chr1_156731241_+ | SINE | Alu | Name=AluSx |
| ADediting_35439 | chr1_156731253_+ | SINE | Alu | Name=AluSx |
| ADediting_35440 | chr1_156731276_+ | SINE | Alu | Name=AluSx |
| ADediting_35441 | chr1_156731304_+ | SINE | Alu | Name=AluSx |
| ADediting_35442 | chr1_156731324_+ | SINE | Alu | Name=AluSx |
| ADediting_35443 | chr1_156731326_+ | SINE | Alu | Name=AluSx |
| ADediting_35444 | chr1_156731333_+ | SINE | Alu | Name=AluSx |
| ADediting_35445 | chr1_156731358_+ | SINE | Alu | Name=AluSx |
| ADediting_35446 | chr1_156731385_+ | SINE | Alu | Name=AluSx |
| ADediting_35447 | chr1_156731386_+ | SINE | Alu | Name=AluSx |
| ADediting_35448 | chr1_156731398_+ | SINE | Alu | Name=AluSx |
| ADediting_35450 | chr1_156734587_+ | SINE | Alu | Name=AluY |
| ADediting_35451 | chr1_156734606_+ | SINE | Alu | Name=AluY |
| ADediting_35452 | chr1_156734611_+ | SINE | Alu | Name=AluY |
| ADediting_35453 | chr1_156734612_+ | SINE | Alu | Name=AluY |
| ADediting_35454 | chr1_156734631_+ | SINE | Alu | Name=AluY |
| ADediting_35455 | chr1_156734642_+ | SINE | Alu | Name=AluY |
| ADediting_35456 | chr1_156734649_+ | SINE | Alu | Name=AluY |
| ADediting_35457 | chr1_156734661_+ | SINE | Alu | Name=AluY |
| ADediting_35458 | chr1_156734671_+ | SINE | Alu | Name=AluY |
| ADediting_35459 | chr1_156734698_+ | SINE | Alu | Name=AluY |
| ADediting_35460 | chr1_156734713_+ | SINE | Alu | Name=AluY |
| ADediting_35461 | chr1_156734716_+ | SINE | Alu | Name=AluY |
| ADediting_35462 | chr1_156734718_+ | SINE | Alu | Name=AluY |
| ADediting_35463 | chr1_156734738_+ | SINE | Alu | Name=AluY |
| ADediting_35464 | chr1_156734742_+ | SINE | Alu | Name=AluY |
| ADediting_35465 | chr1_156734753_+ | SINE | Alu | Name=AluY |
| ADediting_35466 | chr1_156734792_+ | SINE | Alu | Name=AluY |
| ADediting_35467 | chr1_156734793_+ | SINE | Alu | Name=AluY |
| ADediting_35468 | chr1_156734805_+ | SINE | Alu | Name=AluY |
| ADediting_35469 | chr1_156734807_+ | SINE | Alu | Name=AluY |
| ADediting_35470 | chr1_156734823_+ | SINE | Alu | Name=AluY |
| ADediting_35472 | chr1_156735011_+ | SINE | Alu | Name=AluSx |
| ADediting_35473 | chr1_156735025_+ | SINE | Alu | Name=AluSx |
| ADediting_35474 | chr1_156735033_+ | SINE | Alu | Name=AluSx |
| ADediting_35475 | chr1_156735034_+ | SINE | Alu | Name=AluSx |
| ADediting_35476 | chr1_156735039_+ | SINE | Alu | Name=AluSx |
| ADediting_35477 | chr1_156735050_+ | SINE | Alu | Name=AluSx |
| ADediting_35478 | chr1_156735079_+ | SINE | Alu | Name=AluSx |
| ADediting_35479 | chr1_156735102_+ | SINE | Alu | Name=AluSx |
| ADediting_35480 | chr1_156735103_+ | SINE | Alu | Name=AluSx |
| ADediting_35481 | chr1_156735105_+ | SINE | Alu | Name=AluSx |
| ADediting_35482 | chr1_156735113_+ | SINE | Alu | Name=AluSx |
| ADediting_35483 | chr1_156735124_+ | SINE | Alu | Name=AluSx |
| ADediting_35484 | chr1_156735127_+ | SINE | Alu | Name=AluSx |
| ADediting_35485 | chr1_156735128_+ | SINE | Alu | Name=AluSx |
| ADediting_35486 | chr1_156735129_+ | SINE | Alu | Name=AluSx |
| ADediting_35487 | chr1_156735130_+ | SINE | Alu | Name=AluSx |
| ADediting_35488 | chr1_156735133_+ | SINE | Alu | Name=AluSx |
| ADediting_35489 | chr1_156735142_+ | SINE | Alu | Name=AluSx |
| ADediting_35490 | chr1_156735146_+ | SINE | Alu | Name=AluSx |
| ADediting_35491 | chr1_156735158_+ | SINE | Alu | Name=AluSx |
| ADediting_35492 | chr1_156735168_+ | SINE | Alu | Name=AluSx |
| ADediting_35493 | chr1_156735169_+ | SINE | Alu | Name=AluSx |
| ADediting_35494 | chr1_156735191_+ | SINE | Alu | Name=AluSx |
| ADediting_35495 | chr1_156735199_+ | SINE | Alu | Name=AluSx |
| ADediting_35496 | chr1_156735210_+ | SINE | Alu | Name=AluSx |
| ADediting_35497 | chr1_156735223_+ | SINE | Alu | Name=AluSx |
| ADediting_35498 | chr1_156735230_+ | SINE | Alu | Name=AluSx |
| ADediting_35499 | chr1_156735234_+ | SINE | Alu | Name=AluSx |
| ADediting_35500 | chr1_156735235_+ | SINE | Alu | Name=AluSx |
| ADediting_35501 | chr1_156735239_+ | SINE | Alu | Name=AluSx |
| ADediting_35502 | chr1_156735241_+ | SINE | Alu | Name=AluSx |
| ADediting_35503 | chr1_156735422_+ | SINE | Alu | Name=FLAM_C |
| ADediting_35504 | chr1_156735444_+ | SINE | Alu | Name=FLAM_C |
| ADediting_35505 | chr1_156735445_+ | SINE | Alu | Name=FLAM_C |
| ADediting_35506 | chr1_156735466_+ | SINE | Alu | Name=FLAM_C |
| ADediting_35507 | chr1_156736126_+ | SINE | Alu | Name=AluSz |
| ADediting_35508 | chr1_156736267_+ | SINE | Alu | Name=AluSz |
| ADediting_1515845 | chr1_156730460_+ | SINE | Alu | Name=AluSx |
| ADediting_1515846 | chr1_156730509_+ | SINE | Alu | Name=AluSx |
| ADediting_1515847 | chr1_156730589_+ | SINE | Alu | Name=AluSx |
| ADediting_1515848 | chr1_156730673_+ | SINE | Alu | Name=AluSx |
| ADediting_1515849 | chr1_156731263_+ | SINE | Alu | Name=AluSx |
| ADediting_1515850 | chr1_156735277_+ | SINE | Alu | Name=AluSx |
| ADediting_1515851 | chr1_156736221_+ | SINE | Alu | Name=AluSz |
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RNA A-to-I editing events in the alternative splicing sites for RRNAD1 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for RRNAD1 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for RRNAD1 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for RRNAD1 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_35508 | chr1_156736267_+ | ENSG00000143303.12 | ENST00000481920.1 | RRNAD1-205 | hsa-miR-4659a-3p | chr1 | 156736266 | 156736272 | 7mer-m8 | 156736254 | 156736273 | 141 | -10.75 |
| ADediting_35508 | chr1_156736267_+ | ENSG00000143303.12 | ENST00000481920.1 | RRNAD1-205 | hsa-miR-4659b-3p | chr1 | 156736266 | 156736272 | 7mer-m8 | 156736252 | 156736273 | 140 | -10.75 |
| ADediting_35508 | chr1_156736267_+ | ENSG00000143303.12 | ENST00000481920.1 | RRNAD1-205 | hsa-miR-5001-3p | chr1 | 156736262 | 156736269 | 8mer-1a | 156736245 | 156736269 | 153 | -23.63 |
| ADediting_35508 | chr1_156736267_+ | ENSG00000143303.12 | ENST00000481920.1 | RRNAD1-205 | hsa-miR-6738-3p | chr1 | 156736263 | 156736269 | 7mer-m8 | 156736249 | 156736270 | 156 | -26.49 |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_35449 | chr1_156734112_+ | ENSG00000143303.12 | ENST00000462397.1 | RRNAD1-203 | hsa-miR-3173-5p | chr1 | 156734111 | 156734117 | 7mer-1a | 156734095 | 156734122 | 149 | -24.88 |
| ADediting_35449 | chr1_156734112_+ | ENSG00000143303.12 | ENST00000462397.1 | RRNAD1-203 | hsa-miR-4732-3p | chr1 | 156734109 | 156734115 | 7mer-m8 | 156734096 | 156734116 | 147 | -22.9 |
| ADediting_35449 | chr1_156734112_+ | ENSG00000143303.12 | ENST00000462397.1 | RRNAD1-203 | hsa-miR-6730-3p | chr1 | 156734107 | 156734113 | 7mer-m8 | 156734093 | 156734114 | 145 | -18.88 |
| ADediting_35449 | chr1_156734112_+ | ENSG00000143303.12 | ENST00000462397.1 | RRNAD1-203 | hsa-miR-7976 | chr1 | 156734110 | 156734117 | 8mer-1a | 156734096 | 156734117 | 148 | -22.34 |
| ADediting_35449 | chr1_156734112_+ | ENSG00000143303.12 | ENST00000462397.1 | RRNAD1-203 | hsa-miR-874-3p | chr1 | 156734111 | 156734117 | 7mer-m8 | 156734097 | 156734118 | 155 | -30.59 |
| ADediting_35508 | chr1_156736267_+ | ENSG00000143303.12 | ENST00000481920.1 | RRNAD1-205 | hsa-miR-3152-5p | chr1 | 156736261 | 156736268 | 8mer-1a | 156736246 | 156736268 | 143 | -15.6 |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337757 | chr7_5495852_- | ENSG00000143303.12 | ENST00000368218.8 | RRNAD1-202 | hsa-miR-589-3p | chr1 | 156736728 | 156736734 | 7mer-m8 | 156736709 | 156736735 | 150 | -25.34 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000143303.12 | ENST00000476229.5 | RRNAD1-204 | hsa-miR-589-3p | chr1 | 156736728 | 156736734 | 7mer-m8 | 156736709 | 156736735 | 150 | -25.34 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for RRNAD1 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000368216.9 | protein_coding |  |  |
| ENST00000519086.5 | protein_coding |  |  |
| ENST00000462397.1 | lncRNA |  |  |
| ENST00000481920.1 | lncRNA |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_35449 | ENST00000368216.9 | chr1_156734112_+ | 1376 | -969.50 | -969.80 | -969.50 |
| ADediting_35449 | ENST00000519086.5 | chr1_156734112_+ | 833 | -509.20 | -509.50 | -509.20 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_35449 | ENST00000462397.1 | chr1_156734112_+ | 258 | -115.30 | -113.90 | -115.30 |
| ADediting_1515851 | ENST00000481920.1 | chr1_156736221_+ | 64 | -233.80 | -231.80 | -233.80 |
| ADediting_35508 | ENST00000481920.1 | chr1_156736267_+ | 110 | -231.00 | -231.80 | -233.80 |
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Relation with ADAR for RRNAD1 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_35420 | chr1_156730462_+ | 9.65452127784476e-09 | 0.44717518888431 | 1.46130153645543e-07 | 0.413364351101311 | 0.00193313513024033 | 0.251170232003253 |
| CER | ADediting_35421 | chr1_156730469_+ | 2.50769188838688e-07 | 0.406179039564443 | 6.78221012854139e-09 | 0.451310365011079 | 0.00286622275198487 | 0.241855714093177 |
| CER | ADediting_35422 | chr1_156730528_+ | 3.98303973512397e-06 | 0.366469788445882 | 9.3390063904434e-07 | 0.38794488823707 | 0.284712169819301 | 0.0879144846255496 |
| DLPFC | ADediting_35423 | chr1_156730538_+ | 0.119555151493909 | 0.0885953792653026 | 0.65311425456547 | -0.025625808349466 | 1.64975918796771e-10 | 0.352671307405352 |
| CER | ADediting_35423 | chr1_156730538_+ | 0.000294268889223178 | 0.291585015194712 | 2.01932899016996e-06 | 0.376718171460151 | 0.107486019142773 | 0.131951511756817 |
| DLPFC | ADediting_35424 | chr1_156730540_+ | 0.173662229954906 | 0.0774697026175313 | 0.844601495004609 | -0.0111774877208161 | 2.01409481180554e-08 | 0.31194455492595 |
| CER | ADediting_35424 | chr1_156730540_+ | 0.00746511551222228 | 0.217637275927739 | 7.01286819089521e-06 | 0.357658183828164 | 0.103638072598391 | 0.133403421937695 |
| DLPFC | ADediting_35426 | chr1_156730621_+ | 0.0203679228077802 | 0.131696498749377 | 0.863977103139636 | 0.009769197744222 | 2.23122986126975e-10 | 0.350279337858165 |
| CER | ADediting_35426 | chr1_156730621_+ | 0.00328318127615269 | 0.238561779562705 | 2.98273312977907e-05 | 0.333831073790639 | 0.773801879174542 | 0.0236612087172414 |
| DLPFC | ADediting_35427 | chr1_156730650_+ | 0.273565708175072 | 0.062376873100927 | 0.209677443419148 | -0.0714456775936167 | 3.01593688136895e-15 | 0.428106078562996 |
| DLPFC | ADediting_35429 | chr1_156730653_+ | 0.511863271079076 | 0.0373928675779124 | 0.157383017780109 | -0.080500537997431 | 1.92400902411958e-12 | 0.385810787136688 |
| CER | ADediting_35430 | chr1_156730682_+ | 4.97928262879328e-05 | 0.324905993980187 | 7.67643049487498e-08 | 0.421715995691183 | 0.00385027612620609 | 0.234640985279453 |
| DLPFC | ADediting_35431 | chr1_156730707_+ | 0.0715355283200893 | 0.102494639713669 | 0.974072389863171 | 0.0018534277456821 | 1.30542463161241e-11 | 0.372017160991928 |
| CER | ADediting_35431 | chr1_156730707_+ | 6.62604390110101e-05 | 0.319806292521063 | 6.79680503066316e-08 | 0.423269747470209 | 0.0747780150507526 | 0.145926213492691 |
| CER | ADediting_35432 | chr1_156731167_+ | 1.65540170800189e-14 | 0.573770554708835 | 6.06363077602777e-18 | 0.629683016977716 | 0.00246410715025223 | 0.245471548933139 |
| CER | ADediting_35433 | chr1_156731185_+ | 9.68469329540909e-12 | 0.519458204453104 | 2.28142099711773e-14 | 0.571259312985925 | 0.228477354237307 | 0.0989160311925681 |
| CER | ADediting_35434 | chr1_156731187_+ | 5.3706654981914e-09 | 0.454013066676999 | 1.21357994772087e-13 | 0.557818728410275 | 0.164872664615275 | 0.113984242438199 |
| CER | ADediting_35435 | chr1_156731188_+ | 0.000814720417893189 | 0.270491227315276 | 0.000146184970969403 | 0.305184214498366 | 0.114431911224057 | 0.129430680671802 |
| CER | ADediting_35436 | chr1_156731192_+ | 1.26809725992833e-08 | 0.443943947824133 | 6.07062501891022e-12 | 0.523787519944139 | 0.353058442156993 | 0.076353826666201 |
| CER | ADediting_35437 | chr1_156731224_+ | 1.98328129061884e-08 | 0.438570193892213 | 8.65367686910589e-10 | 0.47438259999211 | 0.15774393264852 | 0.115926977367989 |
| CER | ADediting_35438 | chr1_156731241_+ | 7.64179951647203e-08 | 0.421773861768329 | 1.20862529539069e-09 | 0.470753330943977 | 0.388835677210874 | 0.0708643276258177 |
| CER | ADediting_35439 | chr1_156731253_+ | 3.06515286031366e-07 | 0.403464705370201 | 1.64773290523398e-10 | 0.491797650104269 | 0.0241916971464459 | 0.184008999244182 |
| DLPFC | ADediting_35442 | chr1_156731324_+ | 0.0135995092589543 | 0.140028804265456 | 0.74955224656623 | 0.0182030689433284 | 2.23558809192616e-14 | 0.415614540634135 |
| CER | ADediting_35442 | chr1_156731324_+ | 3.80087885535687e-06 | 0.367187424054191 | 5.1898788380028e-08 | 0.42668588567735 | 0.501025545683993 | 0.0553611431691318 |
| DLPFC | ADediting_35443 | chr1_156731326_+ | 0.049633661925217 | 0.111599337973346 | 0.957547513511157 | -0.00303559819596785 | 8.96752419545263e-13 | 0.391134646893882 |
| CER | ADediting_35443 | chr1_156731326_+ | 3.448817687384e-05 | 0.331330288315333 | 1.38158054627984e-07 | 0.414101221641051 | 0.421895274709554 | 0.0660568323979268 |
| DLPFC | ADediting_35444 | chr1_156731333_+ | 0.0089634999410206 | 0.148211679177113 | 0.222767781518942 | 0.0694428941478212 | 6.09466203731158e-08 | 0.301632768433016 |
| CER | ADediting_35444 | chr1_156731333_+ | 5.37445121987373e-05 | 0.323551792179524 | 6.14046247479157e-08 | 0.424560294798135 | 0.123560384010949 | 0.126292942539418 |
| DLPFC | ADediting_35445 | chr1_156731358_+ | 0.000578170756563663 | 0.194390173596058 | 0.0738881165607422 | 0.101659674769499 | 8.80782981299263e-09 | 0.319397583907307 |
| CER | ADediting_35446 | chr1_156731385_+ | 3.3843645515942e-09 | 0.459293197188504 | 1.11744189745898e-09 | 0.471609284066392 | 0.0102752299364437 | 0.208977107820216 |
| TCX | ADediting_35446 | chr1_156731385_+ | 0.33669298633897 | 0.0789805468514995 | 0.631423658296118 | -0.0394843249395963 | 8.02419766829636e-05 | 0.31633727836697 |
| CER | ADediting_35447 | chr1_156731386_+ | 0.00496652082237492 | 0.228243687089087 | 0.000110470059141701 | 0.310448008009837 | 0.100145296893164 | 0.134758508115975 |
| CER | ADediting_35448 | chr1_156731398_+ | 3.17935218711442e-08 | 0.432796898760896 | 1.02796615677341e-08 | 0.44643467613288 | 0.0620366920633939 | 0.152743468857475 |
| DLPFC | ADediting_35449 | chr1_156734112_+ | 1.60609311416903e-06 | 0.268546455511562 | 1.03500683948658e-08 | 0.317959637006405 | 0.536033360351311 | 0.0352783243902363 |
| TCX | ADediting_35468 | chr1_156734805_+ | 0.22328066742415 | -0.100024272177427 | 0.000447357042381492 | -0.283108034982391 | 7.81494316412552e-06 | 0.355941168560996 |
| TCX | ADediting_35480 | chr1_156735103_+ | 0.832821895835999 | -0.0173790003653268 | 0.0562539496488078 | -0.156222782035788 | 4.27152512587805e-06 | 0.365394616000538 |
| TCX | ADediting_35483 | chr1_156735124_+ | 0.194393733580624 | -0.106545412314523 | 0.000301073283545034 | -0.29112912826463 | 7.50413056904423e-07 | 0.391055146179636 |
| TCX | ADediting_35484 | chr1_156735127_+ | 0.517771766111813 | -0.0532174381503029 | 0.00368499491063139 | -0.235726888842977 | 5.92310808703732e-07 | 0.39438370628305 |
| TCX | ADediting_35486 | chr1_156735129_+ | 0.310654150680494 | -0.0833335734027516 | 0.0956963085378742 | -0.136539693929202 | 4.70916412947891e-05 | 0.325890968084969 |
| TCX | ADediting_35490 | chr1_156735146_+ | 0.420478569008497 | -0.0662582082246666 | 0.0120645146109413 | -0.204501074981262 | 9.27410732718949e-05 | 0.313685737263116 |
| TCX | ADediting_35492 | chr1_156735168_+ | 0.137371836422566 | -0.121869654011106 | 0.00963140536131244 | -0.210757110674335 | 0.000128805351162622 | 0.307574821880453 |
| TCX | ADediting_35493 | chr1_156735169_+ | 0.0906957966663314 | -0.138621820306805 | 5.94258029919255e-06 | -0.360264834819542 | 1.17041825655192e-07 | 0.416269634799405 |
| TCX | ADediting_35500 | chr1_156735235_+ | 0.440500674505017 | -0.0634475793268067 | 0.0207097818511673 | -0.188752699148091 | 2.52992347143563e-05 | 0.336641112716591 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 3.67091400466533e-12 | 0.381228968360473 | 1.80286541277618e-16 | 0.444843726690495 | 4.44648550696109e-27 | 0.560826877581487 |
| AC | 1.91470546251111e-34 | 0.673821198072887 | 1.70879318237513e-19 | 0.529810904982526 | 6.98732414727325e-28 | 0.61943018931843 |
| PCC | 1.64516727259881e-08 | 0.394414767375336 | 7.01986292484975e-10 | 0.427350975650347 | 4.07804938545734e-05 | 0.292292673800891 |
| TCX | 0.00459441738399012 | 0.230218549936382 | 0.481200301940694 | -0.0579482528804635 | 4.39206510074568e-21 | 0.672462343690692 |
| FP | 2.53010270724515e-20 | 0.620482317682843 | 5.14767051832915e-16 | 0.55892661549384 | 6.75735075515502e-16 | 0.557041523972233 |
| IFG | 0.0198823672475456 | 0.462619440059629 | 0.00319139783824048 | 0.565924217615962 | 0.0254847031981136 | 0.445884573304704 |
| PG | 0.00310339755556451 | 0.215735235503495 | 0.00138053480383659 | 0.232876111633337 | 1.96681836560983e-09 | 0.422090558349374 |
| STG | 6.46950477755482e-07 | 0.511877721467517 | 0.0101999909381922 | 0.278891848677914 | 9.98238134796315e-09 | 0.575872335173878 |
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Relation with AD stages for RRNAD1 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_35436 | chr1_156731192_+ | 0.000247122806294044 | 0.345766675779216 |
| CER | ADediting_35439 | chr1_156731253_+ | 0.00114188370263215 | 0.308922595608755 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| TCX | 1.16754697466641e-06 | 0.451777412475911 |
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RelatedDrugs for RRNAD1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for RRNAD1 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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