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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for FIS1 |
 Gene summary |
| Gene information | Gene symbol | FIS1 | Gene ID | 51024 |
| Gene name | fission, mitochondrial 1 | |
| Synonyms | CGI-135|TTC11 | |
| Cytomap | 7q22.1 | |
| Type of gene | protein-coding | |
| Description | mitochondrial fission 1 proteinFIS1 homologH_NH0132A01.6TPR repeat protein 11fission 1 (mitochondrial outer membrane) homologhFis1mitochondrial fission moleculetetratricopeptide repeat domain 11tetratricopeptide repeat protein 11 | |
| Modification date | 20200327 | |
| UniProtAcc | Q9Y3D6, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| FIS1 | GO:0000266 | mitochondrial fission | 16118244|18845145 |
| FIS1 | GO:0000422 | autophagy of mitochondrion | 18515060 |
| FIS1 | GO:0016559 | peroxisome fission | 16107562|17408615 |
| FIS1 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process | 16118244|17545159 |
| FIS1 | GO:0090141 | positive regulation of mitochondrial fission | 23283981 |
| FIS1 | GO:0090314 | positive regulation of protein targeting to membrane | 23283981 |
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RNA A-to-I events for FIS1 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_1286496(101241283, -), ADediting_1286497(101241297, -), ADediting_1286498(101241341, -), ADediting_1286499(101241381, -), ADediting_1286500(101241385, -), ADediting_1286501(101241389, -), ADediting_1286502(101241396, -), ADediting_1286503(101241715, -), ADediting_1286504(101241725, -), ADediting_1286505(101241743, -), ADediting_1286506(101241757, -), ADediting_1286507(101241768, -), ADediting_1286508(101241794, -), ADediting_1286509(101241831, -), ADediting_1286510(101241835, -), ADediting_1286511(101241837, -), ADediting_1286512(101241847, -), ADediting_1286513(101241872, -), ADediting_1286514(101241873, -), ADediting_1286515(101241876, -), ADediting_1286516(101241896, -), ADediting_1286517(101241912, -), ADediting_1286518(101241913, -), ADediting_1286519(101241920, -), ADediting_1286520(101242017, -), ADediting_1286521(101242042, -), ADediting_1286522(101242068, -), ADediting_1286523(101242078, -), ADediting_1286524(101242080, -), ADediting_1286525(101242100, -), ADediting_1286526(101242104, -), ADediting_1286527(101242157, -), ADediting_1286528(101242198, -), ADediting_1286529(101242207, -), ADediting_1286530(101242221, -), ADediting_1286531(101242557, -), ADediting_1286532(101242565, -), ADediting_1286533(101242574, -), ADediting_1286534(101242576, -), ADediting_1286535(101242585, -), ADediting_1286536(101242591, -), ADediting_1286537(101242594, -), ADediting_1286538(101242613, -), ADediting_1286539(101242621, -), ADediting_1286540(101242653, -), ADediting_1286541(101242656, -), ADediting_1286542(101242662, -), ADediting_1286543(101242668, -), ADediting_1286544(101242671, -), ADediting_1286545(101242682, -), ADediting_1286546(101242697, -), ADediting_1286547(101242716, -), ADediting_1286548(101242733, -), ADediting_1286549(101242738, -), ADediting_1286550(101242766, -), ADediting_1286551(101242782, -), ADediting_1286552(101243297, -), ADediting_1286553(101243319, -), ADediting_1286554(101243346, -), ADediting_1286555(101243384, -), ADediting_1286556(101243393, -), ADediting_1286557(101243410, -), ADediting_1286558(101243444, -), ADediting_1286559(101243489, -), ADediting_1286560(101243490, -), ADediting_1286561(101243506, -), ADediting_1286562(101243509, -), ADediting_1286563(101243512, -), ADediting_1286564(101243523, -), ADediting_1286565(101243539, -), ADediting_1286566(101243542, -), ADediting_1286567(101245548, -), ADediting_1286568(101245568, -), ADediting_1286569(101245574, -), ADediting_1286570(101245629, -), ADediting_1286571(101245641, -), ADediting_1286572(101245658, -), ADediting_1286573(101245659, -), ADediting_1286574(101245672, -), ADediting_1286575(101245711, -), ADediting_1286576(101245727, -), ADediting_1286577(101245728, -), ADediting_1286578(101246395, -), ADediting_1286579(101246396, -), ADediting_1286580(101246399, -), ADediting_1286581(101246415, -), ADediting_1286582(101246434, -), ADediting_1286583(101246438, -), ADediting_1286584(101246439, -), ADediting_1286585(101246455, -), ADediting_1286586(101246461, -), ADediting_1286587(101246467, -), ADediting_1286588(101246590, -), ADediting_1286589(101246594, -), ADediting_1286590(101246608, -), ADediting_1286591(101246612, -), ADediting_1286592(101246626, -), ADediting_1286593(101246635, -), ADediting_1286594(101246636, -), ADediting_1286595(101246662, -), ADediting_1286596(101246686, -), ADediting_1286597(101246691, -), ADediting_1286598(101246693, -), ADediting_1286599(101246694, -), ADediting_1286600(101246706, -), ADediting_1286601(101246724, -), ADediting_1286602(101246744, -), ADediting_1286603(101246770, -), ADediting_1286604(101246779, -), ADediting_1286605(101247370, -), ADediting_1286606(101247374, -), ADediting_1286607(101247382, -), ADediting_1286608(101247399, -), ADediting_1286609(101247899, -), ADediting_1286610(101247911, -), ADediting_1286611(101247974, -), ADediting_1286612(101247997, -), ADediting_1286613(101248035, -), ADediting_1286614(101248047, -), ADediting_1286615(101248665, -), ADediting_1286616(101248702, -), ADediting_1286617(101248726, -), ADediting_1286618(101248743, -), ADediting_1286619(101248769, -), ADediting_1286620(101248781, -), ADediting_1286621(101248798, -), ADediting_1286622(101248818, -), ADediting_1286623(101249086, -), ADediting_1286624(101249094, -), ADediting_1286625(101249122, -), ADediting_1286626(101249133, -), ADediting_1286627(101249145, -), ADediting_1286628(101249149, -), ADediting_1286629(101249171, -), ADediting_1286630(101249181, -), ADediting_1286631(101249186, -), ADediting_1286632(101249187, -), ADediting_1286633(101249190, -), ADediting_1286634(101249192, -), ADediting_1286635(101249193, -), ADediting_1286636(101249200, -), ADediting_1286637(101249213, -), ADediting_1286638(101249214, -), ADediting_1286639(101249262, -), ADediting_1286640(101249267, -), ADediting_1286641(101249285, -), ADediting_1286642(101249286, -), ADediting_1286643(101249293, -), ADediting_1286644(101249308, -), ADediting_1286645(101249314, -), ADediting_1286646(101249635, -), ADediting_1286647(101249648, -), ADediting_1286648(101249649, -), ADediting_1286649(101249666, -), ADediting_1286650(101249673, -), ADediting_1286651(101249707, -), ADediting_1286652(101249712, -), ADediting_1286653(101249720, -), ADediting_1286654(101249726, -), ADediting_1286655(101249735, -), ADediting_1286656(101249743, -), ADediting_1286657(101249744, -), ADediting_1286658(101249780, -), ADediting_1286659(101249792, -), ADediting_1286660(101249809, -), ADediting_1286661(101249816, -), ADediting_1286662(101249830, -), ADediting_1286663(101249845, -), ADediting_1286664(101249943, -), ADediting_1286665(101249971, -), ADediting_1286666(101250087, -), ADediting_1286667(101250104, -), ADediting_1286668(101250105, -), ADediting_1286669(101250111, -), ADediting_1286670(101250127, -), ADediting_1286671(101250140, -), ADediting_1286672(101250148, -), ADediting_1286673(101251539, -), ADediting_1286674(101251663, -), ADediting_1286675(101251673, -), ADediting_1286676(101251685, -), ADediting_1286677(101251702, -), ADediting_1585151(101241359, -), ADediting_1585152(101242176, -), ADediting_1585153(101243419, -), ADediting_1585154(101243432, -), ADediting_1585155(101243454, -), ADediting_1585156(101245688, -), ADediting_1585157(101249194, -), ADediting_1585158(101249613, -), |
Top |
RNA editing positional annotations for FIS1 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_1286496 | chr7_101241283_- | intronic |
| ADediting_1286497 | chr7_101241297_- | intronic |
| ADediting_1286498 | chr7_101241341_- | intronic |
| ADediting_1286499 | chr7_101241381_- | intronic |
| ADediting_1286500 | chr7_101241385_- | intronic |
| ADediting_1286501 | chr7_101241389_- | intronic |
| ADediting_1286502 | chr7_101241396_- | intronic |
| ADediting_1286503 | chr7_101241715_- | intronic |
| ADediting_1286504 | chr7_101241725_- | intronic |
| ADediting_1286505 | chr7_101241743_- | intronic |
| ADediting_1286506 | chr7_101241757_- | intronic |
| ADediting_1286507 | chr7_101241768_- | intronic |
| ADediting_1286508 | chr7_101241794_- | intronic |
| ADediting_1286509 | chr7_101241831_- | intronic |
| ADediting_1286510 | chr7_101241835_- | intronic |
| ADediting_1286511 | chr7_101241837_- | intronic |
| ADediting_1286512 | chr7_101241847_- | intronic |
| ADediting_1286513 | chr7_101241872_- | intronic |
| ADediting_1286514 | chr7_101241873_- | intronic |
| ADediting_1286515 | chr7_101241876_- | intronic |
| ADediting_1286516 | chr7_101241896_- | intronic |
| ADediting_1286517 | chr7_101241912_- | intronic |
| ADediting_1286518 | chr7_101241913_- | intronic |
| ADediting_1286519 | chr7_101241920_- | intronic |
| ADediting_1286520 | chr7_101242017_- | intronic |
| ADediting_1286521 | chr7_101242042_- | intronic |
| ADediting_1286522 | chr7_101242068_- | intronic |
| ADediting_1286523 | chr7_101242078_- | intronic |
| ADediting_1286524 | chr7_101242080_- | intronic |
| ADediting_1286525 | chr7_101242100_- | intronic |
| ADediting_1286526 | chr7_101242104_- | intronic |
| ADediting_1286527 | chr7_101242157_- | intronic |
| ADediting_1286528 | chr7_101242198_- | intronic |
| ADediting_1286529 | chr7_101242207_- | intronic |
| ADediting_1286530 | chr7_101242221_- | intronic |
| ADediting_1286531 | chr7_101242557_- | intronic |
| ADediting_1286532 | chr7_101242565_- | intronic |
| ADediting_1286533 | chr7_101242574_- | intronic |
| ADediting_1286534 | chr7_101242576_- | intronic |
| ADediting_1286535 | chr7_101242585_- | intronic |
| ADediting_1286536 | chr7_101242591_- | intronic |
| ADediting_1286537 | chr7_101242594_- | intronic |
| ADediting_1286538 | chr7_101242613_- | intronic |
| ADediting_1286539 | chr7_101242621_- | intronic |
| ADediting_1286540 | chr7_101242653_- | intronic |
| ADediting_1286541 | chr7_101242656_- | intronic |
| ADediting_1286542 | chr7_101242662_- | intronic |
| ADediting_1286543 | chr7_101242668_- | intronic |
| ADediting_1286544 | chr7_101242671_- | intronic |
| ADediting_1286545 | chr7_101242682_- | intronic |
| ADediting_1286546 | chr7_101242697_- | intronic |
| ADediting_1286547 | chr7_101242716_- | intronic |
| ADediting_1286548 | chr7_101242733_- | intronic |
| ADediting_1286549 | chr7_101242738_- | intronic |
| ADediting_1286550 | chr7_101242766_- | intronic |
| ADediting_1286551 | chr7_101242782_- | intronic |
| ADediting_1286552 | chr7_101243297_- | intronic |
| ADediting_1286553 | chr7_101243319_- | intronic |
| ADediting_1286554 | chr7_101243346_- | intronic |
| ADediting_1286555 | chr7_101243384_- | intronic |
| ADediting_1286556 | chr7_101243393_- | intronic |
| ADediting_1286557 | chr7_101243410_- | intronic |
| ADediting_1286558 | chr7_101243444_- | intronic |
| ADediting_1286559 | chr7_101243489_- | intronic |
| ADediting_1286560 | chr7_101243490_- | intronic |
| ADediting_1286561 | chr7_101243506_- | intronic |
| ADediting_1286562 | chr7_101243509_- | intronic |
| ADediting_1286563 | chr7_101243512_- | intronic |
| ADediting_1286564 | chr7_101243523_- | intronic |
| ADediting_1286565 | chr7_101243539_- | intronic |
| ADediting_1286566 | chr7_101243542_- | intronic |
| ADediting_1286567 | chr7_101245548_- | intronic |
| ADediting_1286568 | chr7_101245568_- | intronic |
| ADediting_1286569 | chr7_101245574_- | intronic |
| ADediting_1286570 | chr7_101245629_- | intronic |
| ADediting_1286571 | chr7_101245641_- | intronic |
| ADediting_1286572 | chr7_101245658_- | intronic |
| ADediting_1286573 | chr7_101245659_- | intronic |
| ADediting_1286574 | chr7_101245672_- | intronic |
| ADediting_1286575 | chr7_101245711_- | intronic |
| ADediting_1286576 | chr7_101245727_- | intronic |
| ADediting_1286577 | chr7_101245728_- | intronic |
| ADediting_1286578 | chr7_101246395_- | intronic |
| ADediting_1286579 | chr7_101246396_- | intronic |
| ADediting_1286580 | chr7_101246399_- | intronic |
| ADediting_1286581 | chr7_101246415_- | intronic |
| ADediting_1286582 | chr7_101246434_- | intronic |
| ADediting_1286583 | chr7_101246438_- | intronic |
| ADediting_1286584 | chr7_101246439_- | intronic |
| ADediting_1286585 | chr7_101246455_- | intronic |
| ADediting_1286586 | chr7_101246461_- | intronic |
| ADediting_1286587 | chr7_101246467_- | intronic |
| ADediting_1286588 | chr7_101246590_- | intronic |
| ADediting_1286589 | chr7_101246594_- | intronic |
| ADediting_1286590 | chr7_101246608_- | intronic |
| ADediting_1286591 | chr7_101246612_- | intronic |
| ADediting_1286592 | chr7_101246626_- | intronic |
| ADediting_1286593 | chr7_101246635_- | intronic |
| ADediting_1286594 | chr7_101246636_- | intronic |
| ADediting_1286595 | chr7_101246662_- | intronic |
| ADediting_1286596 | chr7_101246686_- | intronic |
| ADediting_1286597 | chr7_101246691_- | intronic |
| ADediting_1286598 | chr7_101246693_- | intronic |
| ADediting_1286599 | chr7_101246694_- | intronic |
| ADediting_1286600 | chr7_101246706_- | intronic |
| ADediting_1286601 | chr7_101246724_- | intronic |
| ADediting_1286602 | chr7_101246744_- | intronic |
| ADediting_1286603 | chr7_101246770_- | intronic |
| ADediting_1286604 | chr7_101246779_- | intronic |
| ADediting_1286605 | chr7_101247370_- | intronic |
| ADediting_1286606 | chr7_101247374_- | intronic |
| ADediting_1286607 | chr7_101247382_- | intronic |
| ADediting_1286608 | chr7_101247399_- | intronic |
| ADediting_1286609 | chr7_101247899_- | intronic |
| ADediting_1286610 | chr7_101247911_- | intronic |
| ADediting_1286611 | chr7_101247974_- | intronic |
| ADediting_1286612 | chr7_101247997_- | intronic |
| ADediting_1286613 | chr7_101248035_- | intronic |
| ADediting_1286614 | chr7_101248047_- | intronic |
| ADediting_1286615 | chr7_101248665_- | intronic |
| ADediting_1286616 | chr7_101248702_- | intronic |
| ADediting_1286617 | chr7_101248726_- | intronic |
| ADediting_1286618 | chr7_101248743_- | intronic |
| ADediting_1286619 | chr7_101248769_- | intronic |
| ADediting_1286620 | chr7_101248781_- | intronic |
| ADediting_1286621 | chr7_101248798_- | intronic |
| ADediting_1286622 | chr7_101248818_- | intronic |
| ADediting_1286623 | chr7_101249086_- | intronic |
| ADediting_1286624 | chr7_101249094_- | intronic |
| ADediting_1286625 | chr7_101249122_- | intronic |
| ADediting_1286626 | chr7_101249133_- | intronic |
| ADediting_1286627 | chr7_101249145_- | intronic |
| ADediting_1286628 | chr7_101249149_- | intronic |
| ADediting_1286629 | chr7_101249171_- | intronic |
| ADediting_1286630 | chr7_101249181_- | intronic |
| ADediting_1286631 | chr7_101249186_- | intronic |
| ADediting_1286632 | chr7_101249187_- | intronic |
| ADediting_1286633 | chr7_101249190_- | intronic |
| ADediting_1286634 | chr7_101249192_- | intronic |
| ADediting_1286635 | chr7_101249193_- | intronic |
| ADediting_1286636 | chr7_101249200_- | intronic |
| ADediting_1286637 | chr7_101249213_- | intronic |
| ADediting_1286638 | chr7_101249214_- | intronic |
| ADediting_1286639 | chr7_101249262_- | intronic |
| ADediting_1286640 | chr7_101249267_- | intronic |
| ADediting_1286641 | chr7_101249285_- | intronic |
| ADediting_1286642 | chr7_101249286_- | intronic |
| ADediting_1286643 | chr7_101249293_- | intronic |
| ADediting_1286644 | chr7_101249308_- | intronic |
| ADediting_1286645 | chr7_101249314_- | intronic |
| ADediting_1286646 | chr7_101249635_- | intronic |
| ADediting_1286647 | chr7_101249648_- | intronic |
| ADediting_1286648 | chr7_101249649_- | intronic |
| ADediting_1286649 | chr7_101249666_- | intronic |
| ADediting_1286650 | chr7_101249673_- | intronic |
| ADediting_1286651 | chr7_101249707_- | intronic |
| ADediting_1286652 | chr7_101249712_- | intronic |
| ADediting_1286653 | chr7_101249720_- | intronic |
| ADediting_1286654 | chr7_101249726_- | intronic |
| ADediting_1286655 | chr7_101249735_- | intronic |
| ADediting_1286656 | chr7_101249743_- | intronic |
| ADediting_1286657 | chr7_101249744_- | intronic |
| ADediting_1286658 | chr7_101249780_- | intronic |
| ADediting_1286659 | chr7_101249792_- | intronic |
| ADediting_1286660 | chr7_101249809_- | intronic |
| ADediting_1286661 | chr7_101249816_- | intronic |
| ADediting_1286662 | chr7_101249830_- | intronic |
| ADediting_1286663 | chr7_101249845_- | intronic |
| ADediting_1286664 | chr7_101249943_- | intronic |
| ADediting_1286665 | chr7_101249971_- | intronic |
| ADediting_1286666 | chr7_101250087_- | intronic |
| ADediting_1286667 | chr7_101250104_- | intronic |
| ADediting_1286668 | chr7_101250105_- | intronic |
| ADediting_1286669 | chr7_101250111_- | intronic |
| ADediting_1286670 | chr7_101250127_- | intronic |
| ADediting_1286671 | chr7_101250140_- | intronic |
| ADediting_1286672 | chr7_101250148_- | intronic |
| ADediting_1286673 | chr7_101251539_- | intronic |
| ADediting_1286674 | chr7_101251663_- | intronic |
| ADediting_1286675 | chr7_101251673_- | intronic |
| ADediting_1286676 | chr7_101251685_- | intronic |
| ADediting_1286677 | chr7_101251702_- | intronic |
| ADediting_1585151 | chr7_101241359_- | intronic |
| ADediting_1585152 | chr7_101242176_- | intronic |
| ADediting_1585153 | chr7_101243419_- | intronic |
| ADediting_1585154 | chr7_101243432_- | intronic |
| ADediting_1585155 | chr7_101243454_- | intronic |
| ADediting_1585156 | chr7_101245688_- | intronic |
| ADediting_1585157 | chr7_101249194_- | intronic |
| ADediting_1585158 | chr7_101249613_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_1286496 | chr7_101241283_- | SINE | Alu | Name=AluSq2 |
| ADediting_1286497 | chr7_101241297_- | SINE | Alu | Name=AluSq2 |
| ADediting_1286498 | chr7_101241341_- | SINE | Alu | Name=AluSq2 |
| ADediting_1286499 | chr7_101241381_- | SINE | Alu | Name=AluSq2 |
| ADediting_1286500 | chr7_101241385_- | SINE | Alu | Name=AluSq2 |
| ADediting_1286501 | chr7_101241389_- | SINE | Alu | Name=AluSq2 |
| ADediting_1286502 | chr7_101241396_- | SINE | Alu | Name=AluSq2 |
| ADediting_1286503 | chr7_101241715_- | SINE | Alu | Name=AluSp |
| ADediting_1286504 | chr7_101241725_- | SINE | Alu | Name=AluSp |
| ADediting_1286505 | chr7_101241743_- | SINE | Alu | Name=AluSp |
| ADediting_1286506 | chr7_101241757_- | SINE | Alu | Name=AluSp |
| ADediting_1286507 | chr7_101241768_- | SINE | Alu | Name=AluSp |
| ADediting_1286508 | chr7_101241794_- | SINE | Alu | Name=AluSp |
| ADediting_1286509 | chr7_101241831_- | SINE | Alu | Name=AluSp |
| ADediting_1286510 | chr7_101241835_- | SINE | Alu | Name=AluSp |
| ADediting_1286511 | chr7_101241837_- | SINE | Alu | Name=AluSp |
| ADediting_1286512 | chr7_101241847_- | SINE | Alu | Name=AluSp |
| ADediting_1286513 | chr7_101241872_- | SINE | Alu | Name=AluSp |
| ADediting_1286514 | chr7_101241873_- | SINE | Alu | Name=AluSp |
| ADediting_1286515 | chr7_101241876_- | SINE | Alu | Name=AluSp |
| ADediting_1286516 | chr7_101241896_- | SINE | Alu | Name=AluSp |
| ADediting_1286517 | chr7_101241912_- | SINE | Alu | Name=AluSp |
| ADediting_1286518 | chr7_101241913_- | SINE | Alu | Name=AluSp |
| ADediting_1286519 | chr7_101241920_- | SINE | Alu | Name=AluSp |
| ADediting_1286520 | chr7_101242017_- | SINE | Alu | Name=AluJr |
| ADediting_1286521 | chr7_101242042_- | SINE | Alu | Name=AluJr |
| ADediting_1286522 | chr7_101242068_- | SINE | Alu | Name=AluJr |
| ADediting_1286523 | chr7_101242078_- | SINE | Alu | Name=AluJr |
| ADediting_1286524 | chr7_101242080_- | SINE | Alu | Name=AluJr |
| ADediting_1286525 | chr7_101242100_- | SINE | Alu | Name=AluJr |
| ADediting_1286526 | chr7_101242104_- | SINE | Alu | Name=AluJr |
| ADediting_1286527 | chr7_101242157_- | SINE | Alu | Name=AluJr |
| ADediting_1286528 | chr7_101242198_- | SINE | Alu | Name=AluJr |
| ADediting_1286529 | chr7_101242207_- | SINE | Alu | Name=AluJr |
| ADediting_1286530 | chr7_101242221_- | SINE | Alu | Name=AluJr |
| ADediting_1286531 | chr7_101242557_- | SINE | Alu | Name=AluSg |
| ADediting_1286532 | chr7_101242565_- | SINE | Alu | Name=AluSg |
| ADediting_1286533 | chr7_101242574_- | SINE | Alu | Name=AluSg |
| ADediting_1286534 | chr7_101242576_- | SINE | Alu | Name=AluSg |
| ADediting_1286535 | chr7_101242585_- | SINE | Alu | Name=AluSg |
| ADediting_1286536 | chr7_101242591_- | SINE | Alu | Name=AluSg |
| ADediting_1286537 | chr7_101242594_- | SINE | Alu | Name=AluSg |
| ADediting_1286538 | chr7_101242613_- | SINE | Alu | Name=AluSg |
| ADediting_1286539 | chr7_101242621_- | SINE | Alu | Name=AluSg |
| ADediting_1286540 | chr7_101242653_- | SINE | Alu | Name=AluSg |
| ADediting_1286541 | chr7_101242656_- | SINE | Alu | Name=AluSg |
| ADediting_1286542 | chr7_101242662_- | SINE | Alu | Name=AluSg |
| ADediting_1286543 | chr7_101242668_- | SINE | Alu | Name=AluSg |
| ADediting_1286544 | chr7_101242671_- | SINE | Alu | Name=AluSg |
| ADediting_1286545 | chr7_101242682_- | SINE | Alu | Name=AluSg |
| ADediting_1286546 | chr7_101242697_- | SINE | Alu | Name=AluSg |
| ADediting_1286547 | chr7_101242716_- | SINE | Alu | Name=AluSg |
| ADediting_1286548 | chr7_101242733_- | SINE | Alu | Name=AluSg |
| ADediting_1286549 | chr7_101242738_- | SINE | Alu | Name=AluSg |
| ADediting_1286550 | chr7_101242766_- | SINE | Alu | Name=AluSg |
| ADediting_1286551 | chr7_101242782_- | SINE | Alu | Name=AluSg |
| ADediting_1286552 | chr7_101243297_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286553 | chr7_101243319_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286554 | chr7_101243346_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286555 | chr7_101243384_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286556 | chr7_101243393_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286557 | chr7_101243410_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286558 | chr7_101243444_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286559 | chr7_101243489_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286560 | chr7_101243490_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286561 | chr7_101243506_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286562 | chr7_101243509_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286563 | chr7_101243512_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286564 | chr7_101243523_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286565 | chr7_101243539_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286566 | chr7_101243542_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286567 | chr7_101245548_- | SINE | Alu | Name=AluJr |
| ADediting_1286568 | chr7_101245568_- | SINE | Alu | Name=AluJr |
| ADediting_1286569 | chr7_101245574_- | SINE | Alu | Name=AluJr |
| ADediting_1286570 | chr7_101245629_- | SINE | Alu | Name=AluJr |
| ADediting_1286571 | chr7_101245641_- | SINE | Alu | Name=AluJr |
| ADediting_1286572 | chr7_101245658_- | SINE | Alu | Name=AluJr |
| ADediting_1286573 | chr7_101245659_- | SINE | Alu | Name=AluJr |
| ADediting_1286574 | chr7_101245672_- | SINE | Alu | Name=AluJr |
| ADediting_1286575 | chr7_101245711_- | SINE | Alu | Name=AluJr |
| ADediting_1286576 | chr7_101245727_- | SINE | Alu | Name=AluJr |
| ADediting_1286577 | chr7_101245728_- | SINE | Alu | Name=AluJr |
| ADediting_1286578 | chr7_101246395_- | SINE | Alu | Name=AluJb |
| ADediting_1286579 | chr7_101246396_- | SINE | Alu | Name=AluJb |
| ADediting_1286580 | chr7_101246399_- | SINE | Alu | Name=AluJb |
| ADediting_1286581 | chr7_101246415_- | SINE | Alu | Name=AluJb |
| ADediting_1286582 | chr7_101246434_- | SINE | Alu | Name=AluJb |
| ADediting_1286583 | chr7_101246438_- | SINE | Alu | Name=AluJb |
| ADediting_1286584 | chr7_101246439_- | SINE | Alu | Name=AluJb |
| ADediting_1286585 | chr7_101246455_- | SINE | Alu | Name=AluJb |
| ADediting_1286586 | chr7_101246461_- | SINE | Alu | Name=AluJb |
| ADediting_1286587 | chr7_101246467_- | SINE | Alu | Name=AluJb |
| ADediting_1286588 | chr7_101246590_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286589 | chr7_101246594_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286590 | chr7_101246608_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286591 | chr7_101246612_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286592 | chr7_101246626_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286593 | chr7_101246635_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286594 | chr7_101246636_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286595 | chr7_101246662_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286596 | chr7_101246686_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286597 | chr7_101246691_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286598 | chr7_101246693_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286599 | chr7_101246694_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286600 | chr7_101246706_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286601 | chr7_101246724_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286602 | chr7_101246744_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286603 | chr7_101246770_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286604 | chr7_101246779_- | SINE | Alu | Name=AluSx1 |
| ADediting_1286605 | chr7_101247370_- | SINE | Alu | Name=AluSx |
| ADediting_1286606 | chr7_101247374_- | SINE | Alu | Name=AluSx |
| ADediting_1286607 | chr7_101247382_- | SINE | Alu | Name=AluSx |
| ADediting_1286608 | chr7_101247399_- | SINE | Alu | Name=AluSx |
| ADediting_1286609 | chr7_101247899_- | SINE | Alu | Name=AluY |
| ADediting_1286610 | chr7_101247911_- | SINE | Alu | Name=AluY |
| ADediting_1286611 | chr7_101247974_- | SINE | Alu | Name=AluY |
| ADediting_1286612 | chr7_101247997_- | SINE | Alu | Name=AluY |
| ADediting_1286613 | chr7_101248035_- | SINE | Alu | Name=AluY |
| ADediting_1286614 | chr7_101248047_- | SINE | Alu | Name=AluY |
| ADediting_1286615 | chr7_101248665_- | SINE | Alu | Name=AluSp |
| ADediting_1286616 | chr7_101248702_- | SINE | Alu | Name=AluSp |
| ADediting_1286617 | chr7_101248726_- | SINE | Alu | Name=AluSp |
| ADediting_1286618 | chr7_101248743_- | SINE | Alu | Name=AluSp |
| ADediting_1286619 | chr7_101248769_- | SINE | Alu | Name=AluSp |
| ADediting_1286620 | chr7_101248781_- | SINE | Alu | Name=AluSp |
| ADediting_1286621 | chr7_101248798_- | SINE | Alu | Name=AluSp |
| ADediting_1286622 | chr7_101248818_- | SINE | Alu | Name=AluSp |
| ADediting_1286623 | chr7_101249086_- | SINE | Alu | Name=AluJb |
| ADediting_1286624 | chr7_101249094_- | SINE | Alu | Name=AluJb |
| ADediting_1286625 | chr7_101249122_- | SINE | Alu | Name=AluJb |
| ADediting_1286626 | chr7_101249133_- | SINE | Alu | Name=AluJb |
| ADediting_1286627 | chr7_101249145_- | SINE | Alu | Name=AluJb |
| ADediting_1286628 | chr7_101249149_- | SINE | Alu | Name=AluJb |
| ADediting_1286629 | chr7_101249171_- | SINE | Alu | Name=AluJb |
| ADediting_1286630 | chr7_101249181_- | SINE | Alu | Name=AluJb |
| ADediting_1286631 | chr7_101249186_- | SINE | Alu | Name=AluJb |
| ADediting_1286632 | chr7_101249187_- | SINE | Alu | Name=AluJb |
| ADediting_1286633 | chr7_101249190_- | SINE | Alu | Name=AluJb |
| ADediting_1286634 | chr7_101249192_- | SINE | Alu | Name=AluJb |
| ADediting_1286635 | chr7_101249193_- | SINE | Alu | Name=AluJb |
| ADediting_1286636 | chr7_101249200_- | SINE | Alu | Name=AluJb |
| ADediting_1286637 | chr7_101249213_- | SINE | Alu | Name=AluJb |
| ADediting_1286638 | chr7_101249214_- | SINE | Alu | Name=AluJb |
| ADediting_1286639 | chr7_101249262_- | SINE | Alu | Name=AluJb |
| ADediting_1286640 | chr7_101249267_- | SINE | Alu | Name=AluJb |
| ADediting_1286641 | chr7_101249285_- | SINE | Alu | Name=AluJb |
| ADediting_1286642 | chr7_101249286_- | SINE | Alu | Name=AluJb |
| ADediting_1286643 | chr7_101249293_- | SINE | Alu | Name=AluJb |
| ADediting_1286644 | chr7_101249308_- | SINE | Alu | Name=AluJb |
| ADediting_1286645 | chr7_101249314_- | SINE | Alu | Name=AluJb |
| ADediting_1286646 | chr7_101249635_- | SINE | Alu | Name=AluSz |
| ADediting_1286647 | chr7_101249648_- | SINE | Alu | Name=AluSz |
| ADediting_1286648 | chr7_101249649_- | SINE | Alu | Name=AluSz |
| ADediting_1286649 | chr7_101249666_- | SINE | Alu | Name=AluSz |
| ADediting_1286650 | chr7_101249673_- | SINE | Alu | Name=AluSz |
| ADediting_1286651 | chr7_101249707_- | SINE | Alu | Name=AluSz |
| ADediting_1286652 | chr7_101249712_- | SINE | Alu | Name=AluSz |
| ADediting_1286653 | chr7_101249720_- | SINE | Alu | Name=AluSz |
| ADediting_1286654 | chr7_101249726_- | SINE | Alu | Name=AluSz |
| ADediting_1286655 | chr7_101249735_- | SINE | Alu | Name=AluSz |
| ADediting_1286656 | chr7_101249743_- | SINE | Alu | Name=AluSz |
| ADediting_1286657 | chr7_101249744_- | SINE | Alu | Name=AluSz |
| ADediting_1286658 | chr7_101249780_- | SINE | Alu | Name=AluSz |
| ADediting_1286659 | chr7_101249792_- | SINE | Alu | Name=AluSz |
| ADediting_1286660 | chr7_101249809_- | SINE | Alu | Name=AluSz |
| ADediting_1286661 | chr7_101249816_- | SINE | Alu | Name=AluSz |
| ADediting_1286662 | chr7_101249830_- | SINE | Alu | Name=AluSz |
| ADediting_1286663 | chr7_101249845_- | SINE | Alu | Name=AluSz |
| ADediting_1286664 | chr7_101249943_- | SINE | Alu | Name=AluSp |
| ADediting_1286665 | chr7_101249971_- | SINE | Alu | Name=AluSp |
| ADediting_1286666 | chr7_101250087_- | SINE | Alu | Name=AluSp |
| ADediting_1286667 | chr7_101250104_- | SINE | Alu | Name=AluSp |
| ADediting_1286668 | chr7_101250105_- | SINE | Alu | Name=AluSp |
| ADediting_1286669 | chr7_101250111_- | SINE | Alu | Name=AluSp |
| ADediting_1286670 | chr7_101250127_- | SINE | Alu | Name=AluSp |
| ADediting_1286671 | chr7_101250140_- | SINE | Alu | Name=AluSp |
| ADediting_1286672 | chr7_101250148_- | SINE | Alu | Name=AluSp |
| ADediting_1286673 | chr7_101251539_- | SINE | Alu | Name=AluSz |
| ADediting_1286674 | chr7_101251663_- | SINE | Alu | Name=AluSz |
| ADediting_1286675 | chr7_101251673_- | SINE | Alu | Name=AluSz |
| ADediting_1286676 | chr7_101251685_- | SINE | Alu | Name=AluSz |
| ADediting_1286677 | chr7_101251702_- | SINE | Alu | Name=AluSz |
| ADediting_1585151 | chr7_101241359_- | SINE | Alu | Name=AluSq2 |
| ADediting_1585152 | chr7_101242176_- | SINE | Alu | Name=AluJr |
| ADediting_1585153 | chr7_101243419_- | SINE | Alu | Name=AluSx1 |
| ADediting_1585154 | chr7_101243432_- | SINE | Alu | Name=AluSx1 |
| ADediting_1585155 | chr7_101243454_- | SINE | Alu | Name=AluSx1 |
| ADediting_1585156 | chr7_101245688_- | SINE | Alu | Name=AluJr |
| ADediting_1585157 | chr7_101249194_- | SINE | Alu | Name=AluJb |
| ADediting_1585158 | chr7_101249613_- | SINE | Alu | Name=AluSz |
Top |
RNA A-to-I editing events in the alternative splicing sites for FIS1 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for FIS1 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for FIS1 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for FIS1 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1286503 | chr7_101241715_- | ENSG00000214253.9 | ENST00000482199.5 | FIS1-209 | hsa-miR-3189-3p | chr7 | 101241714 | 101241720 | 7mer-m8 | 101241713 | 101241736 | 149 | -24.98 |
| ADediting_1286503 | chr7_101241715_- | ENSG00000214253.9 | ENST00000482199.5 | FIS1-209 | hsa-miR-6813-3p | chr7 | 101241713 | 101241719 | 7mer-m8 | 101241712 | 101241732 | 140 | -11.43 |
| ADediting_1286504 | chr7_101241725_- | ENSG00000214253.9 | ENST00000482199.5 | FIS1-209 | hsa-miR-615-3p | chr7 | 101241724 | 101241730 | 7mer-m8 | 101241723 | 101241746 | 153 | -27.06 |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1286504 | chr7_101241725_- | ENSG00000214253.9 | ENST00000482199.5 | FIS1-209 | hsa-miR-1199-5p | chr7 | 101241724 | 101241730 | 7mer-m8 | 101241723 | 101241741 | 153 | -23.49 |
| ADediting_1286504 | chr7_101241725_- | ENSG00000214253.9 | ENST00000482199.5 | FIS1-209 | hsa-miR-4663 | chr7 | 101241723 | 101241729 | 7mer-m8 | 101241722 | 101241745 | 148 | -21.18 |
| ADediting_1286504 | chr7_101241725_- | ENSG00000214253.9 | ENST00000482199.5 | FIS1-209 | hsa-miR-6751-3p | chr7 | 101241724 | 101241730 | 7mer-m8 | 101241723 | 101241743 | 140 | -15.57 |
| ADediting_1286505 | chr7_101241743_- | ENSG00000214253.9 | ENST00000482199.5 | FIS1-209 | hsa-miR-3622a-3p | chr7 | 101241738 | 101241745 | 8mer-1a | 101241738 | 101241759 | 144 | -13.51 |
| ADediting_1286505 | chr7_101241743_- | ENSG00000214253.9 | ENST00000482199.5 | FIS1-209 | hsa-miR-3622b-3p | chr7 | 101241738 | 101241745 | 8mer-1a | 101241738 | 101241758 | 153 | -18.32 |
| ADediting_1286505 | chr7_101241743_- | ENSG00000214253.9 | ENST00000482199.5 | FIS1-209 | hsa-miR-7162-3p | chr7 | 101241742 | 101241748 | 7mer-m8 | 101241741 | 101241760 | 143 | -16.6 |
| ADediting_1286507 | chr7_101241768_- | ENSG00000214253.9 | ENST00000482199.5 | FIS1-209 | hsa-miR-4293 | chr7 | 101241764 | 101241770 | 7mer-m8 | 101241763 | 101241779 | 146 | -21.19 |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for FIS1 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000482199.5 | lncRNA |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_1286503 | ENST00000482199.5 | chr7_101241715_- | 71 | -280.60 | -280.60 | -285.90 |
| ADediting_1286504 | ENST00000482199.5 | chr7_101241725_- | 61 | -279.90 | -280.60 | -285.90 |
| ADediting_1286505 | ENST00000482199.5 | chr7_101241743_- | 43 | -281.10 | -280.60 | -285.90 |
| ADediting_1286506 | ENST00000482199.5 | chr7_101241757_- | 29 | -280.60 | -280.60 | -285.90 |
| ADediting_1286507 | ENST00000482199.5 | chr7_101241768_- | 18 | -286.50 | -280.60 | -285.90 |
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Relation with ADAR for FIS1 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_1286503 | chr7_101241715_- | 0.0899574088813954 | 0.0964698614831839 | 0.956200172942345 | -0.00313203580604687 | 6.56380266491261e-12 | 0.377045408981011 |
| DLPFC | ADediting_1286506 | chr7_101241757_- | 0.118760393673832 | 0.088785535463712 | 0.872776315349345 | -0.00913164260069571 | 2.05269858544604e-11 | 0.368658885760423 |
| DLPFC | ADediting_1286507 | chr7_101241768_- | 0.0584396109186426 | 0.107602721589563 | 0.59626954470469 | -0.0302042183320369 | 1.04257409889762e-14 | 0.420432551689265 |
| DLPFC | ADediting_1286514 | chr7_101241873_- | 0.237492708014543 | 0.067287787470813 | 0.769017011513658 | -0.0167452974766524 | 2.0072953756431e-08 | 0.311975448263904 |
| DLPFC | ADediting_1286516 | chr7_101241896_- | 0.00168446791192895 | 0.177685625246941 | 0.289302758347548 | 0.0603731913041778 | 5.65650223190069e-08 | 0.302340264374508 |
| DLPFC | ADediting_1286517 | chr7_101241912_- | 0.039799606902887 | 0.116834698937455 | 0.603481124726517 | 0.0296131545050601 | 1.58690059085011e-09 | 0.334223573237759 |
| DLPFC | ADediting_1286518 | chr7_101241913_- | 0.0170605572949167 | 0.135404107566408 | 0.570704186986896 | 0.0323264444699422 | 6.8386716654081e-14 | 0.408409914386042 |
| DLPFC | ADediting_1286536 | chr7_101242591_- | 0.975434236562159 | 0.00175604505058511 | 0.0151335830025154 | -0.137864896882413 | 7.99784077641568e-21 | 0.497889867911 |
| DLPFC | ADediting_1286540 | chr7_101242653_- | 0.0744359129108738 | 0.101468366641229 | 0.25532511185636 | -0.0648000854027694 | 2.28981119381405e-16 | 0.443458481080017 |
| DLPFC | ADediting_1286547 | chr7_101242716_- | 0.63602589404988 | -0.0269836174219162 | 0.0182281568156759 | -0.134028877442753 | 1.60471141931082e-09 | 0.33412954808348 |
| DLPFC | ADediting_1286548 | chr7_101242733_- | 0.750644933844512 | 0.0181209289365972 | 0.144792554656713 | -0.0830110707706596 | 1.01358879202049e-12 | 0.390286959223356 |
| DLPFC | ADediting_1286551 | chr7_101242782_- | 0.0966991304874612 | 0.0945130272201479 | 0.996370831528045 | -0.000259385509649163 | 2.65993359192553e-16 | 0.442587161253044 |
| DLPFC | ADediting_1286554 | chr7_101243346_- | 0.00775480038768201 | 0.150965641231192 | 0.0465864688607366 | 0.113120651056 | 3.52262139472399e-09 | 0.327424381329032 |
| DLPFC | ADediting_1286555 | chr7_101243384_- | 0.0567580394142028 | 0.108325352685139 | 0.251427904332748 | 0.0653331772225357 | 1.22864597978827e-08 | 0.316422832161502 |
| DLPFC | ADediting_1286556 | chr7_101243393_- | 0.101033935889069 | 0.0933115283591678 | 0.480519926733345 | 0.0402140529713123 | 3.02975043155969e-13 | 0.398541212046374 |
| DLPFC | ADediting_1286561 | chr7_101243506_- | 0.0353492947573021 | 0.119572086862439 | 0.244839012766455 | 0.0662476700284966 | 4.8736684963894e-10 | 0.343994349821006 |
| DLPFC | ADediting_1286564 | chr7_101243523_- | 5.4628585645276e-06 | 0.25495596858917 | 0.000612316061335374 | 0.193528372113334 | 2.42350624758896e-09 | 0.330633968795271 |
| DLPFC | ADediting_1286565 | chr7_101243539_- | 4.32434074419896e-07 | 0.282332957151041 | 0.000290765474684034 | 0.204442891908089 | 2.28235494484294e-10 | 0.350099042648523 |
| DLPFC | ADediting_1286571 | chr7_101245641_- | 0.112782201839286 | 0.090248708177484 | 0.662599717272864 | -0.0248783572882632 | 9.45351656348296e-18 | 0.461426045917589 |
| DLPFC | ADediting_1286584 | chr7_101246439_- | 0.210988757291675 | 0.0712410733570302 | 0.845584852381219 | -0.0111058572938263 | 2.41741045520531e-14 | 0.415116277507823 |
| DLPFC | ADediting_1286588 | chr7_101246590_- | 0.34936282575859 | 0.0533289447070263 | 0.441184902118736 | -0.0439003250606027 | 2.85115774701515e-14 | 0.414061955197159 |
| DLPFC | ADediting_1286593 | chr7_101246635_- | 0.0511306868091594 | 0.110880346733737 | 0.651254169210442 | 0.0257728938825677 | 3.30179056144976e-17 | 0.454501418258485 |
| DLPFC | ADediting_1286609 | chr7_101247899_- | 0.00710332119441299 | 0.152613026353766 | 0.217317767129714 | 0.0702662081244151 | 9.30530544896953e-11 | 0.357153562704215 |
| DLPFC | ADediting_1286624 | chr7_101249094_- | 0.218756717202016 | -0.0700474112342487 | 0.00952617616821406 | -0.147040889365216 | 5.52368209343602e-11 | 0.361175767075608 |
| DLPFC | ADediting_1286627 | chr7_101249145_- | 0.882163843575312 | 0.00845270861003708 | 0.125053226928587 | -0.0873061688191899 | 3.88278270480304e-13 | 0.396864220563525 |
| DLPFC | ADediting_1286629 | chr7_101249171_- | 0.994987291526279 | 0.000358271599228769 | 0.0338108361601431 | -0.120586655291714 | 1.54453267575769e-19 | 0.483156874044148 |
| DLPFC | ADediting_1286630 | chr7_101249181_- | 0.399199252869903 | 0.0480485899015531 | 0.137866464601115 | -0.0844637734891484 | 1.1914820094894e-21 | 0.507001342367954 |
| DLPFC | ADediting_1286642 | chr7_101249286_- | 0.725265367455337 | 0.0200388616162953 | 0.343284605943136 | -0.0540043503576635 | 2.83091109257648e-08 | 0.30881623514527 |
| DLPFC | ADediting_1286649 | chr7_101249666_- | 0.0545638559240587 | 0.109295423997313 | 0.801407885143079 | -0.0143428927482447 | 1.69533951230762e-19 | 0.482681542265152 |
| DLPFC | ADediting_1286659 | chr7_101249792_- | 0.924825476089886 | 0.00538082280741164 | 0.0919843935087683 | -0.0958695366684278 | 5.50396770932757e-10 | 0.343003287937734 |
| DLPFC | ADediting_1286660 | chr7_101249809_- | 0.842299580190262 | 0.0113452343195033 | 0.28344601524544 | -0.0611100865950324 | 5.37909210645019e-08 | 0.302816059800936 |
| DLPFC | ADediting_1286661 | chr7_101249816_- | 0.108701797883018 | 0.0912826993326208 | 0.534367513097002 | -0.0354224894159204 | 4.32437541456591e-09 | 0.325648566401025 |
| DLPFC | ADediting_1286666 | chr7_101250087_- | 0.710208981265882 | 0.0211872888368251 | 0.473782450087533 | -0.0408332691417167 | 2.77836830649177e-09 | 0.329465563584352 |
| DLPFC | ADediting_1286667 | chr7_101250104_- | 0.101646041494813 | 0.0931451817523667 | 0.986896487646627 | 0.000936578625618587 | 8.30041513578669e-10 | 0.339629470118703 |
| DLPFC | ADediting_1286670 | chr7_101250127_- | 0.494927043374662 | 0.0389055080015126 | 0.431828420638074 | -0.0448041610482389 | 1.33276655381057e-10 | 0.354349708800386 |
| DLPFC | ADediting_1286675 | chr7_101251673_- | 0.0384087914366543 | 0.117661085382839 | 0.293489983153441 | 0.0598524668259295 | 1.69253946388728e-08 | 0.313529030289728 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 4.7133936286738e-31 | 0.594839865409577 | 3.76597323328022e-42 | 0.672457455252893 | 1.61607142792404e-08 | 0.31394861244371 |
| AC | 3.01184751939155e-54 | 0.788387577021337 | 4.79584146311116e-37 | 0.692579729808328 | 3.4015841337117e-21 | 0.550324181151788 |
| PCC | 3.95613995653314e-16 | 0.544379224991549 | 2.72505584699433e-17 | 0.56193236150149 | 0.016231295525658 | 0.173739318905332 |
| TCX | 1.54565707830451e-05 | 0.344891806464345 | 0.634847163423557 | 0.0390888635206631 | 1.30033682847005e-08 | 0.443644743373216 |
| FP | 9.3590218024201e-07 | 0.357890863379816 | 2.77660464402456e-10 | 0.450567242964141 | 0.891909943004856 | 0.0102572218124886 |
| IFG | 0.00415128961564898 | 0.552893625693361 | 0.0734616570502005 | 0.364225198443783 | 0.743064396145459 | 0.0690146690950879 |
| STG | 7.53890515547413e-12 | 0.661308832900071 | 3.81181514522474e-08 | 0.556737867288278 | 0.333409070679949 | 0.106836184281375 |
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Relation with AD stages for FIS1 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| PG | 5.70246148328542e-07 | -0.356947523231529 |
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RelatedDrugs for FIS1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for FIS1 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| FIS1 | C2931673 | Ceroid lipofuscinosis, neuronal 1, infantile | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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