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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for TMED5 |
 Gene summary |
| Gene information | Gene symbol | TMED5 | Gene ID | 50999 |
| Gene name | transmembrane p24 trafficking protein 5 | |
| Synonyms | CGI-100|p24g2|p28 | |
| Cytomap | 1p22.1 | |
| Type of gene | protein-coding | |
| Description | transmembrane emp24 domain-containing protein 5p24 family protein gamma-2p24gamma2transmembrane emp24 protein transport domain containing 5 | |
| Modification date | 20200313 | |
| UniProtAcc | Q9Y3A6, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for TMED5 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_150103(93155021, -), ADediting_150104(93155114, -), ADediting_150105(93155117, -), ADediting_150106(93155118, -), ADediting_150107(93155143, -), ADediting_150108(93155163, -), ADediting_150109(93155573, -), ADediting_150110(93155661, -), ADediting_150111(93155729, -), ADediting_150112(93155734, -), ADediting_150113(93155735, -), ADediting_150114(93155737, -), ADediting_150115(93155741, -), ADediting_150116(93155750, -), ADediting_150117(93155751, -), ADediting_150118(93155764, -), ADediting_150119(93157935, -), ADediting_150120(93157957, -), ADediting_150121(93157960, -), ADediting_150122(93158002, -), ADediting_150123(93158012, -), ADediting_150124(93158077, -), ADediting_150125(93158667, -), ADediting_150126(93158668, -), ADediting_150127(93158706, -), ADediting_150128(93158716, -), ADediting_150129(93158732, -), ADediting_150130(93158747, -), ADediting_150131(93158761, -), ADediting_150132(93158762, -), ADediting_150133(93158771, -), ADediting_150134(93158791, -), ADediting_150135(93158794, -), ADediting_150136(93158833, -), ADediting_150137(93158838, -), ADediting_150138(93158841, -), ADediting_150139(93158861, -), ADediting_150140(93163711, -), ADediting_150141(93163719, -), ADediting_150142(93168601, -), ADediting_150143(93168759, -), ADediting_150144(93174096, -), ADediting_150145(93174242, -), ADediting_150146(93174385, -), ADediting_150149(93176730, -), ADediting_150150(93176782, -), ADediting_1521817(93155164, -), ADediting_1603221(93163482, -), ADediting_1603222(93163485, -), ADediting_1603223(93163509, -), ADediting_1603224(93163615, -), ADediting_1603225(93163624, -), ADediting_1603226(93163731, -), ADediting_1603227(93163732, -), ADediting_1603228(93163758, -), ADediting_1603229(93163759, -), ADediting_1603230(93163771, -), ADediting_1603231(93176727, -), ADediting_1603232(93176826, -), ADediting_1603233(93179199, -), |
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RNA editing positional annotations for TMED5 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| ADediting_150136 | chr1_93158833_- | nonsynonymous SNV | ENST00000370290.7 | c.A340G | p.S114G | . | . | . |
| ADediting_150137 | chr1_93158838_- | nonsynonymous SNV | ENST00000370290.7 | c.A335G | p.N112S | . | . | . |
| ADediting_150138 | chr1_93158841_- | nonsynonymous SNV | ENST00000370290.7 | c.A332G | p.Y111C | . | . | . |
| ADediting_150139 | chr1_93158861_- | synonymous SNV | ENST00000370290.7 | c.A312G | p.P104P | . | . | . |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_150103 | chr1_93155021_- | intronic |
| ADediting_150104 | chr1_93155114_- | intronic |
| ADediting_150105 | chr1_93155117_- | intronic |
| ADediting_150106 | chr1_93155118_- | intronic |
| ADediting_150107 | chr1_93155143_- | intronic |
| ADediting_150108 | chr1_93155163_- | intronic |
| ADediting_150109 | chr1_93155573_- | intronic |
| ADediting_150110 | chr1_93155661_- | intronic |
| ADediting_150111 | chr1_93155729_- | intronic |
| ADediting_150112 | chr1_93155734_- | intronic |
| ADediting_150113 | chr1_93155735_- | intronic |
| ADediting_150114 | chr1_93155737_- | intronic |
| ADediting_150115 | chr1_93155741_- | intronic |
| ADediting_150116 | chr1_93155750_- | intronic |
| ADediting_150117 | chr1_93155751_- | intronic |
| ADediting_150118 | chr1_93155764_- | intronic |
| ADediting_150119 | chr1_93157935_- | intronic |
| ADediting_150120 | chr1_93157957_- | intronic |
| ADediting_150121 | chr1_93157960_- | intronic |
| ADediting_150122 | chr1_93158002_- | intronic |
| ADediting_150123 | chr1_93158012_- | intronic |
| ADediting_150124 | chr1_93158077_- | intronic |
| ADediting_150125 | chr1_93158667_- | intronic |
| ADediting_150126 | chr1_93158668_- | intronic |
| ADediting_150127 | chr1_93158706_- | intronic |
| ADediting_150128 | chr1_93158716_- | intronic |
| ADediting_150129 | chr1_93158732_- | intronic |
| ADediting_150130 | chr1_93158747_- | intronic |
| ADediting_150131 | chr1_93158761_- | intronic |
| ADediting_150132 | chr1_93158762_- | intronic |
| ADediting_150133 | chr1_93158771_- | intronic |
| ADediting_150134 | chr1_93158791_- | intronic |
| ADediting_150135 | chr1_93158794_- | intronic |
| ADediting_150136 | chr1_93158833_- | exonic |
| ADediting_150137 | chr1_93158838_- | exonic |
| ADediting_150138 | chr1_93158841_- | exonic |
| ADediting_150139 | chr1_93158861_- | exonic |
| ADediting_150140 | chr1_93163711_- | intronic |
| ADediting_150141 | chr1_93163719_- | intronic |
| ADediting_150142 | chr1_93168601_- | intronic |
| ADediting_150143 | chr1_93168759_- | intronic |
| ADediting_150144 | chr1_93174096_- | intronic |
| ADediting_150145 | chr1_93174242_- | intronic |
| ADediting_150146 | chr1_93174385_- | intronic |
| ADediting_150149 | chr1_93176730_- | intronic |
| ADediting_150150 | chr1_93176782_- | intronic |
| ADediting_1521817 | chr1_93155164_- | intronic |
| ADediting_1603221 | chr1_93163482_- | intronic |
| ADediting_1603222 | chr1_93163485_- | intronic |
| ADediting_1603223 | chr1_93163509_- | intronic |
| ADediting_1603224 | chr1_93163615_- | intronic |
| ADediting_1603225 | chr1_93163624_- | intronic |
| ADediting_1603226 | chr1_93163731_- | intronic |
| ADediting_1603227 | chr1_93163732_- | intronic |
| ADediting_1603228 | chr1_93163758_- | intronic |
| ADediting_1603229 | chr1_93163759_- | intronic |
| ADediting_1603230 | chr1_93163771_- | intronic |
| ADediting_1603231 | chr1_93176727_- | intronic |
| ADediting_1603232 | chr1_93176826_- | intronic |
| ADediting_1603233 | chr1_93179199_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_150103 | chr1_93155021_- | SINE | Alu | Name=AluJo |
| ADediting_150104 | chr1_93155114_- | SINE | Alu | Name=AluJo |
| ADediting_150105 | chr1_93155117_- | SINE | Alu | Name=AluJo |
| ADediting_150106 | chr1_93155118_- | SINE | Alu | Name=AluJo |
| ADediting_150107 | chr1_93155143_- | SINE | Alu | Name=AluJo |
| ADediting_150108 | chr1_93155163_- | SINE | Alu | Name=AluJo |
| ADediting_150109 | chr1_93155573_- | SINE | Alu | Name=AluSc5 |
| ADediting_150110 | chr1_93155661_- | SINE | Alu | Name=AluJr |
| ADediting_150111 | chr1_93155729_- | SINE | Alu | Name=AluJr |
| ADediting_150112 | chr1_93155734_- | SINE | Alu | Name=AluJr |
| ADediting_150113 | chr1_93155735_- | SINE | Alu | Name=AluJr |
| ADediting_150114 | chr1_93155737_- | SINE | Alu | Name=AluJr |
| ADediting_150115 | chr1_93155741_- | SINE | Alu | Name=AluJr |
| ADediting_150116 | chr1_93155750_- | SINE | Alu | Name=AluJr |
| ADediting_150117 | chr1_93155751_- | SINE | Alu | Name=AluJr |
| ADediting_150118 | chr1_93155764_- | SINE | Alu | Name=AluJr |
| ADediting_150119 | chr1_93157935_- | SINE | Alu | Name=AluY |
| ADediting_150120 | chr1_93157957_- | SINE | Alu | Name=AluY |
| ADediting_150121 | chr1_93157960_- | SINE | Alu | Name=AluY |
| ADediting_150122 | chr1_93158002_- | SINE | Alu | Name=AluY |
| ADediting_150123 | chr1_93158012_- | SINE | Alu | Name=AluY |
| ADediting_150124 | chr1_93158077_- | SINE | Alu | Name=AluY |
| ADediting_150125 | chr1_93158667_- | SINE | Alu | Name=AluSc |
| ADediting_150126 | chr1_93158668_- | SINE | Alu | Name=AluSc |
| ADediting_150127 | chr1_93158706_- | SINE | Alu | Name=AluSc |
| ADediting_150128 | chr1_93158716_- | SINE | Alu | Name=AluSc |
| ADediting_150129 | chr1_93158732_- | SINE | Alu | Name=AluSc |
| ADediting_150130 | chr1_93158747_- | SINE | Alu | Name=AluSc |
| ADediting_150131 | chr1_93158761_- | SINE | Alu | Name=AluSc |
| ADediting_150132 | chr1_93158762_- | SINE | Alu | Name=AluSc |
| ADediting_150133 | chr1_93158771_- | SINE | Alu | Name=AluSc |
| ADediting_150134 | chr1_93158791_- | SINE | Alu | Name=AluSc |
| ADediting_150135 | chr1_93158794_- | SINE | Alu | Name=AluSc |
| ADediting_150136 | chr1_93158833_- | SINE | Alu | Name=AluSc |
| ADediting_150137 | chr1_93158838_- | SINE | Alu | Name=AluSc |
| ADediting_150138 | chr1_93158841_- | SINE | Alu | Name=AluSc |
| ADediting_150139 | chr1_93158861_- | SINE | Alu | Name=AluSc |
| ADediting_150140 | chr1_93163711_- | SINE | Alu | Name=AluSz |
| ADediting_150141 | chr1_93163719_- | SINE | Alu | Name=AluSz |
| ADediting_150142 | chr1_93168601_- | SINE | Alu | Name=AluSc8 |
| ADediting_150143 | chr1_93168759_- | SINE | Alu | Name=AluSc8 |
| ADediting_150144 | chr1_93174096_- | SINE | Alu | Name=AluSx3 |
| ADediting_150145 | chr1_93174242_- | SINE | Alu | Name=AluSx3 |
| ADediting_150146 | chr1_93174385_- | SINE | Alu | Name=FLAM_A |
| ADediting_150149 | chr1_93176730_- | SINE | Alu | Name=AluJo |
| ADediting_150150 | chr1_93176782_- | SINE | Alu | Name=AluJo |
| ADediting_1521817 | chr1_93155164_- | SINE | Alu | Name=AluJo |
| ADediting_1603221 | chr1_93163482_- | SINE | Alu | Name=AluSz |
| ADediting_1603222 | chr1_93163485_- | SINE | Alu | Name=AluSz |
| ADediting_1603223 | chr1_93163509_- | SINE | Alu | Name=AluSz |
| ADediting_1603224 | chr1_93163615_- | SINE | Alu | Name=AluSz |
| ADediting_1603225 | chr1_93163624_- | SINE | Alu | Name=AluSz |
| ADediting_1603226 | chr1_93163731_- | SINE | Alu | Name=AluSz |
| ADediting_1603227 | chr1_93163732_- | SINE | Alu | Name=AluSz |
| ADediting_1603228 | chr1_93163758_- | SINE | Alu | Name=AluSz |
| ADediting_1603229 | chr1_93163759_- | SINE | Alu | Name=AluSz |
| ADediting_1603230 | chr1_93163771_- | SINE | Alu | Name=AluSz |
| ADediting_1603231 | chr1_93176727_- | SINE | Alu | Name=AluJo |
| ADediting_1603232 | chr1_93176826_- | SINE | Alu | Name=AluJo |
| ADediting_1603233 | chr1_93179199_- | SINE | Alu | Name=AluSx |
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RNA A-to-I editing events in the alternative splicing sites for TMED5 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for TMED5 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for TMED5 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for TMED5 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337757 | chr7_5495852_- | ENSG00000117500.13 | ENST00000370282.8 | TMED5-202 | hsa-miR-589-3p | chr1 | 93152186 | 93152193 | 8mer-1a | 93152186 | 93152209 | 159 | -21 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000117500.13 | ENST00000370282.8 | TMED5-202 | hsa-miR-4477b | chr1 | 93152030 | 93152037 | 8mer-1a | 93152030 | 93152051 | 168 | -16.07 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000117500.13 | ENST00000370282.8 | TMED5-202 | hsa-miR-4477b | chr1 | 93150797 | 93150803 | 7mer-m8 | 93150796 | 93150817 | 143 | -11.77 |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000117500.13 | ENST00000370282.8 | TMED5-202 | hsa-miR-381-3p | chr1 | 93152679 | 93152685 | 7mer-m8 | 93152678 | 93152699 | 146 | -15.42 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000117500.13 | ENST00000370282.8 | TMED5-202 | hsa-miR-641 | chr1 | 93152036 | 93152042 | 7mer-m8 | 93152035 | 93152060 | 157 | -16.65 |
| ADediting_1596844 | chr1_162342605_+ | ENSG00000117500.13 | ENST00000370282.8 | TMED5-202 | hsa-miR-556-3p | chr1 | 93150772 | 93150779 | 8mer-1a | 93150772 | 93150794 | 167 | -15.71 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000117500.13 | ENST00000370282.8 | TMED5-202 | hsa-miR-641 | chr1 | 93150369 | 93150375 | 7mer-m8 | 93150368 | 93150393 | 144 | -16.49 |
| ADediting_496066 | chr15_66496985_- | ENSG00000117500.13 | ENST00000370282.8 | TMED5-202 | hsa-miR-4512 | chr1 | 93152980 | 93152986 | 7mer-m8 | 93152979 | 93153000 | 142 | -13.73 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000117500.13 | ENST00000370282.8 | TMED5-202 | hsa-miR-4775 | chr1 | 93151429 | 93151436 | 8mer-1a | 93151429 | 93151450 | 140 | -15.83 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000117500.13 | ENST00000370282.8 | TMED5-202 | hsa-miR-5585-3p | chr1 | 93153560 | 93153566 | 7mer-m8 | 93153559 | 93153580 | 140 | -9.59 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_107020 | chr1_37500952_- | ENSG00000117500.13 | ENST00000370282.8 | TMED5-202 | hsa-miR-5581-3p | chr1 | 93150273 | 93150279 | 7mer-m8 | 93150272 | 93150293 | 140 | -9.36 |
| ADediting_1535951 | chr14_100874558_+ | ENSG00000117500.13 | ENST00000370282.8 | TMED5-202 | hsa-miR-337-3p | chr1 | 93151348 | 93151355 | 8mer-1a | 93151348 | 93151369 | 155 | -12.38 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000117500.13 | ENST00000370282.8 | TMED5-202 | hsa-miR-641 | chr1 | 93154381 | 93154388 | 8mer-1a | 93154381 | 93154403 | 148 | -10.95 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000117500.13 | ENST00000479918.5 | TMED5-204 | hsa-miR-641 | chr1 | 93154381 | 93154388 | 8mer-1a | 93154381 | 93154403 | 148 | -10.95 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000117500.13 | ENST00000370282.8 | TMED5-202 | hsa-miR-641 | chr1 | 93154381 | 93154388 | 8mer-1a | 93154381 | 93154403 | 148 | -10.95 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000117500.13 | ENST00000479918.5 | TMED5-204 | hsa-miR-641 | chr1 | 93154381 | 93154388 | 8mer-1a | 93154381 | 93154403 | 148 | -10.95 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000117500.13 | ENST00000370282.8 | TMED5-202 | hsa-miR-4775 | chr1 | 93151846 | 93151853 | 8mer-1a | 93151846 | 93151867 | 148 | -5.86 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000117500.13 | ENST00000370282.8 | TMED5-202 | hsa-miR-4775 | chr1 | 93151860 | 93151866 | 7mer-m8 | 93151846 | 93151867 | 148 | -5.86 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000117500.13 | ENST00000370282.8 | TMED5-202 | hsa-miR-4775 | chr1 | 93151860 | 93151866 | 7mer-m8 | 93151859 | 93151884 | 149 | -5.56 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000117500.13 | ENST00000370282.8 | TMED5-202 | hsa-miR-4775 | chr1 | 93152100 | 93152107 | 8mer-1a | 93152100 | 93152121 | 140 | -5.03 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000117500.13 | ENST00000370282.8 | TMED5-202 | hsa-miR-4775 | chr1 | 93153878 | 93153885 | 8mer-1a | 93153878 | 93153899 | 143 | -11.4 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000117500.13 | ENST00000370282.8 | TMED5-202 | hsa-miR-4775 | chr1 | 93153983 | 93153989 | 7mer-m8 | 93153982 | 93154003 | 140 | -8.63 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000117500.13 | ENST00000370282.8 | TMED5-202 | hsa-miR-4775 | chr1 | 93154527 | 93154534 | 8mer-1a | 93154527 | 93154549 | 147 | -4.15 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000117500.13 | ENST00000479918.5 | TMED5-204 | hsa-miR-4775 | chr1 | 93154527 | 93154534 | 8mer-1a | 93154527 | 93154549 | 147 | -4.15 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for TMED5 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for TMED5 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_150106 | chr1_93155118_- | 1.60823281248737e-06 | 0.380075713496383 | 8.06196477135513e-05 | 0.31625166154026 | 0.377832954278278 | -0.0725183051862493 |
| CER | ADediting_150114 | chr1_93155737_- | 9.42661143690555e-08 | 0.419076032524394 | 9.70305706630237e-08 | 0.418702677691645 | 0.408210948937695 | 0.0680187846765708 |
| CER | ADediting_150117 | chr1_93155751_- | 2.22087148556195e-08 | 0.437195783448478 | 1.84688269260101e-10 | 0.490630443223712 | 0.349468170413749 | 0.0769233990072116 |
| CER | ADediting_150118 | chr1_93155764_- | 1.97167754347939e-07 | 0.409399451096237 | 4.05188266062902e-07 | 0.399650471726823 | 0.427885562725671 | 0.0652096518604996 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 9.52174007647799e-29 | 0.575598096033442 | 1.17545884853181e-11 | 0.372789739863778 | 0.742287797266751 | 0.0187501216191623 |
| AC | 6.03734955490342e-62 | 0.819671718665463 | 1.21161157824783e-32 | 0.659967888129441 | 3.44250750836139e-18 | 0.513081334145519 |
| PCC | 3.48945796988919e-28 | 0.68859827036849 | 2.31941395885523e-21 | 0.616262047323224 | 6.63835863794035e-06 | 0.319481404551797 |
| CER | 1.9637483827489e-22 | 0.688887942389811 | 1.05827893590142e-15 | 0.59446179823533 | 2.01562379114116e-06 | 0.376745410956244 |
| TCX | 2.38662084739063e-20 | 0.663049562920023 | 0.0525426393767009 | 0.158614326969294 | 4.80240660900981e-11 | 0.504136544691483 |
| FP | 1.25798102903108e-10 | 0.458262530745621 | 2.94455871502145e-08 | 0.40085604676976 | 5.41046597103006e-05 | 0.297800688156634 |
| IFG | 0.0372328558992112 | 0.418713048082138 | 0.280718657364729 | 0.224465077575276 | 0.186495114262823 | 0.27313023552872 |
| PG | 4.26832257692716e-39 | 0.778659334006054 | 3.73956526340167e-14 | 0.517877448307331 | 0.193244846919912 | 0.0958231637233328 |
| STG | 0.00203864793124026 | 0.331928319919238 | 0.0266710020849749 | 0.241840113407489 | 0.726785309678603 | -0.0386886338308568 |
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Relation with AD stages for TMED5 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 2.32158056889615e-07 | 0.47318441548256 |
| TCX | 7.56585002377613e-09 | 0.525038219459905 |
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RelatedDrugs for TMED5 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for TMED5 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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