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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for OPRM1 |
 Gene summary |
| Gene information | Gene symbol | OPRM1 | Gene ID | 4988 |
| Gene name | opioid receptor mu 1 | |
| Synonyms | LMOR|M-OR-1|MOP|MOR|MOR1|OPRM | |
| Cytomap | 6q25.2 | |
| Type of gene | protein-coding | |
| Description | mu-type opioid receptormu opiate receptormu opioid receptor hMOR-1a | |
| Modification date | 20200322 | |
| UniProtAcc | P35372, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for OPRM1 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_1241664(154055133, +), ADediting_1241665(154074559, +), ADediting_1241666(154074716, +), ADediting_1241667(154074718, +), ADediting_1241668(154074748, +), ADediting_1241669(154074749, +), ADediting_1241670(154075532, +), ADediting_1241671(154075552, +), ADediting_1241672(154075555, +), ADediting_1241673(154075613, +), ADediting_1241674(154075626, +), ADediting_1241675(154075627, +), ADediting_1241676(154075632, +), ADediting_1241677(154075635, +), ADediting_1241678(154075638, +), ADediting_1241679(154078613, +), ADediting_1241680(154078638, +), ADediting_1241681(154078785, +), ADediting_1241682(154083709, +), ADediting_1241683(154083723, +), ADediting_1241684(154083797, +), ADediting_1241685(154095058, +), ADediting_1241686(154095171, +), ADediting_1241687(154096127, +), ADediting_1241688(154096158, +), ADediting_1241689(154096196, +), ADediting_1241690(154099078, +), ADediting_1241691(154099079, +), ADediting_1241692(154099094, +), ADediting_1241693(154099186, +), ADediting_1241694(154099206, +), ADediting_1241695(154110677, +), ADediting_1241696(154110711, +), ADediting_1241702(154126856, +), ADediting_1241703(154126895, +), ADediting_1241704(154126908, +), ADediting_1241705(154126923, +), ADediting_1241706(154126931, +), ADediting_1241707(154126932, +), ADediting_1241708(154126934, +), ADediting_1241709(154126962, +), ADediting_1241710(154126988, +), ADediting_1241711(154126989, +), ADediting_1241712(154126998, +), ADediting_1241713(154127015, +), ADediting_1241714(154127030, +), ADediting_1241715(154127037, +), ADediting_1241716(154127044, +), ADediting_1241717(154127094, +), ADediting_1241718(154130232, +), ADediting_1241719(154130308, +), ADediting_1241720(154130353, +), ADediting_1241721(154130375, +), ADediting_1582916(154073787, +), ADediting_1582917(154075673, +), ADediting_1582918(154077303, +), ADediting_1582919(154077307, +), ADediting_1582920(154077338, +), ADediting_1582921(154077339, +), ADediting_1582922(154077354, +), ADediting_1582923(154077476, +), ADediting_1582924(154077529, +), ADediting_1582925(154078806, +), ADediting_1582926(154078813, +), ADediting_1582927(154078830, +), ADediting_1582928(154079727, +), ADediting_1582929(154079753, +), ADediting_1582930(154079779, +), ADediting_1582931(154079837, +), ADediting_1582932(154079844, +), ADediting_1582933(154083833, +), ADediting_1582934(154086028, +), ADediting_1582935(154086090, +), ADediting_1582936(154126958, +), |
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RNA editing positional annotations for OPRM1 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_1241664 | chr6_154055133_+ | intronic |
| ADediting_1241665 | chr6_154074559_+ | intronic |
| ADediting_1241666 | chr6_154074716_+ | intronic |
| ADediting_1241667 | chr6_154074718_+ | intronic |
| ADediting_1241668 | chr6_154074748_+ | intronic |
| ADediting_1241669 | chr6_154074749_+ | intronic |
| ADediting_1241670 | chr6_154075532_+ | intronic |
| ADediting_1241671 | chr6_154075552_+ | intronic |
| ADediting_1241672 | chr6_154075555_+ | intronic |
| ADediting_1241673 | chr6_154075613_+ | intronic |
| ADediting_1241674 | chr6_154075626_+ | intronic |
| ADediting_1241675 | chr6_154075627_+ | intronic |
| ADediting_1241676 | chr6_154075632_+ | intronic |
| ADediting_1241677 | chr6_154075635_+ | intronic |
| ADediting_1241678 | chr6_154075638_+ | intronic |
| ADediting_1241679 | chr6_154078613_+ | intronic |
| ADediting_1241680 | chr6_154078638_+ | intronic |
| ADediting_1241681 | chr6_154078785_+ | intronic |
| ADediting_1241682 | chr6_154083709_+ | intronic |
| ADediting_1241683 | chr6_154083723_+ | intronic |
| ADediting_1241684 | chr6_154083797_+ | intronic |
| ADediting_1241685 | chr6_154095058_+ | intronic |
| ADediting_1241686 | chr6_154095171_+ | intronic |
| ADediting_1241687 | chr6_154096127_+ | intronic |
| ADediting_1241688 | chr6_154096158_+ | intronic |
| ADediting_1241689 | chr6_154096196_+ | intronic |
| ADediting_1241690 | chr6_154099078_+ | intronic |
| ADediting_1241691 | chr6_154099079_+ | intronic |
| ADediting_1241692 | chr6_154099094_+ | intronic |
| ADediting_1241693 | chr6_154099186_+ | intronic |
| ADediting_1241694 | chr6_154099206_+ | intronic |
| ADediting_1241695 | chr6_154110677_+ | intronic |
| ADediting_1241696 | chr6_154110711_+ | intronic |
| ADediting_1241702 | chr6_154126856_+ | UTR3 |
| ADediting_1241703 | chr6_154126895_+ | UTR3 |
| ADediting_1241704 | chr6_154126908_+ | UTR3 |
| ADediting_1241705 | chr6_154126923_+ | UTR3 |
| ADediting_1241706 | chr6_154126931_+ | UTR3 |
| ADediting_1241707 | chr6_154126932_+ | UTR3 |
| ADediting_1241708 | chr6_154126934_+ | UTR3 |
| ADediting_1241709 | chr6_154126962_+ | UTR3 |
| ADediting_1241710 | chr6_154126988_+ | UTR3 |
| ADediting_1241711 | chr6_154126989_+ | UTR3 |
| ADediting_1241712 | chr6_154126998_+ | UTR3 |
| ADediting_1241713 | chr6_154127015_+ | UTR3 |
| ADediting_1241714 | chr6_154127030_+ | UTR3 |
| ADediting_1241715 | chr6_154127037_+ | UTR3 |
| ADediting_1241716 | chr6_154127044_+ | UTR3 |
| ADediting_1241717 | chr6_154127094_+ | UTR3 |
| ADediting_1241718 | chr6_154130232_+ | UTR3 |
| ADediting_1241719 | chr6_154130308_+ | UTR3 |
| ADediting_1241720 | chr6_154130353_+ | UTR3 |
| ADediting_1241721 | chr6_154130375_+ | UTR3 |
| ADediting_1582916 | chr6_154073787_+ | intronic |
| ADediting_1582917 | chr6_154075673_+ | intronic |
| ADediting_1582918 | chr6_154077303_+ | intronic |
| ADediting_1582919 | chr6_154077307_+ | intronic |
| ADediting_1582920 | chr6_154077338_+ | intronic |
| ADediting_1582921 | chr6_154077339_+ | intronic |
| ADediting_1582922 | chr6_154077354_+ | intronic |
| ADediting_1582923 | chr6_154077476_+ | intronic |
| ADediting_1582924 | chr6_154077529_+ | intronic |
| ADediting_1582925 | chr6_154078806_+ | intronic |
| ADediting_1582926 | chr6_154078813_+ | intronic |
| ADediting_1582927 | chr6_154078830_+ | intronic |
| ADediting_1582928 | chr6_154079727_+ | intronic |
| ADediting_1582929 | chr6_154079753_+ | intronic |
| ADediting_1582930 | chr6_154079779_+ | intronic |
| ADediting_1582931 | chr6_154079837_+ | intronic |
| ADediting_1582932 | chr6_154079844_+ | intronic |
| ADediting_1582933 | chr6_154083833_+ | intronic |
| ADediting_1582934 | chr6_154086028_+ | intronic |
| ADediting_1582935 | chr6_154086090_+ | intronic |
| ADediting_1582936 | chr6_154126958_+ | UTR3 |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_1241664 | chr6_154055133_+ | SINE | Alu | Name=AluSz |
| ADediting_1241665 | chr6_154074559_+ | SINE | Alu | Name=AluSx |
| ADediting_1241666 | chr6_154074716_+ | SINE | Alu | Name=AluSx |
| ADediting_1241667 | chr6_154074718_+ | SINE | Alu | Name=AluSx |
| ADediting_1241668 | chr6_154074748_+ | SINE | Alu | Name=AluSx |
| ADediting_1241669 | chr6_154074749_+ | SINE | Alu | Name=AluSx |
| ADediting_1241670 | chr6_154075532_+ | SINE | Alu | Name=AluSz |
| ADediting_1241671 | chr6_154075552_+ | SINE | Alu | Name=AluSz |
| ADediting_1241672 | chr6_154075555_+ | SINE | Alu | Name=AluSz |
| ADediting_1241673 | chr6_154075613_+ | SINE | Alu | Name=AluSz |
| ADediting_1241674 | chr6_154075626_+ | SINE | Alu | Name=AluSz |
| ADediting_1241675 | chr6_154075627_+ | SINE | Alu | Name=AluSz |
| ADediting_1241676 | chr6_154075632_+ | SINE | Alu | Name=AluSz |
| ADediting_1241677 | chr6_154075635_+ | SINE | Alu | Name=AluSz |
| ADediting_1241678 | chr6_154075638_+ | SINE | Alu | Name=AluSz |
| ADediting_1241679 | chr6_154078613_+ | SINE | Alu | Name=AluJb |
| ADediting_1241680 | chr6_154078638_+ | SINE | Alu | Name=AluJb |
| ADediting_1241681 | chr6_154078785_+ | SINE | Alu | Name=AluJb |
| ADediting_1241682 | chr6_154083709_+ | SINE | Alu | Name=AluY |
| ADediting_1241683 | chr6_154083723_+ | SINE | Alu | Name=AluY |
| ADediting_1241684 | chr6_154083797_+ | SINE | Alu | Name=AluY |
| ADediting_1241685 | chr6_154095058_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1241686 | chr6_154095171_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1241687 | chr6_154096127_+ | SINE | Alu | Name=AluSz |
| ADediting_1241688 | chr6_154096158_+ | SINE | Alu | Name=AluSz |
| ADediting_1241689 | chr6_154096196_+ | SINE | Alu | Name=AluSz |
| ADediting_1241690 | chr6_154099078_+ | SINE | Alu | Name=AluJb |
| ADediting_1241691 | chr6_154099079_+ | SINE | Alu | Name=AluJb |
| ADediting_1241692 | chr6_154099094_+ | SINE | Alu | Name=AluJb |
| ADediting_1241693 | chr6_154099186_+ | SINE | Alu | Name=AluJb |
| ADediting_1241694 | chr6_154099206_+ | SINE | Alu | Name=AluJb |
| ADediting_1241695 | chr6_154110677_+ | SINE | Alu | Name=AluYm1 |
| ADediting_1241696 | chr6_154110711_+ | SINE | Alu | Name=AluYm1 |
| ADediting_1241702 | chr6_154126856_+ | SINE | Alu | Name=AluSg |
| ADediting_1241703 | chr6_154126895_+ | SINE | Alu | Name=AluSg |
| ADediting_1241704 | chr6_154126908_+ | SINE | Alu | Name=AluSg |
| ADediting_1241705 | chr6_154126923_+ | SINE | Alu | Name=AluSg |
| ADediting_1241706 | chr6_154126931_+ | SINE | Alu | Name=AluSg |
| ADediting_1241707 | chr6_154126932_+ | SINE | Alu | Name=AluSg |
| ADediting_1241708 | chr6_154126934_+ | SINE | Alu | Name=AluSg |
| ADediting_1241709 | chr6_154126962_+ | SINE | Alu | Name=AluSg |
| ADediting_1241710 | chr6_154126988_+ | SINE | Alu | Name=AluSg |
| ADediting_1241711 | chr6_154126989_+ | SINE | Alu | Name=AluSg |
| ADediting_1241712 | chr6_154126998_+ | SINE | Alu | Name=AluSg |
| ADediting_1241713 | chr6_154127015_+ | SINE | Alu | Name=AluSg |
| ADediting_1241714 | chr6_154127030_+ | SINE | Alu | Name=AluSg |
| ADediting_1241715 | chr6_154127037_+ | SINE | Alu | Name=AluSg |
| ADediting_1241716 | chr6_154127044_+ | SINE | Alu | Name=AluSg |
| ADediting_1241717 | chr6_154127094_+ | SINE | Alu | Name=AluSg |
| ADediting_1241718 | chr6_154130232_+ | SINE | Alu | Name=AluY |
| ADediting_1241719 | chr6_154130308_+ | SINE | Alu | Name=AluY |
| ADediting_1241720 | chr6_154130353_+ | SINE | Alu | Name=AluY |
| ADediting_1241721 | chr6_154130375_+ | SINE | Alu | Name=AluY |
| ADediting_1582916 | chr6_154073787_+ | SINE | Alu | Name=AluSz6 |
| ADediting_1582917 | chr6_154075673_+ | SINE | Alu | Name=AluSz |
| ADediting_1582918 | chr6_154077303_+ | SINE | Alu | Name=AluSz |
| ADediting_1582919 | chr6_154077307_+ | SINE | Alu | Name=AluSz |
| ADediting_1582920 | chr6_154077338_+ | SINE | Alu | Name=AluSz |
| ADediting_1582921 | chr6_154077339_+ | SINE | Alu | Name=AluSz |
| ADediting_1582922 | chr6_154077354_+ | SINE | Alu | Name=AluSz |
| ADediting_1582923 | chr6_154077476_+ | SINE | Alu | Name=AluSz |
| ADediting_1582924 | chr6_154077529_+ | SINE | Alu | Name=AluSz |
| ADediting_1582925 | chr6_154078806_+ | SINE | Alu | Name=AluJb |
| ADediting_1582926 | chr6_154078813_+ | SINE | Alu | Name=AluJb |
| ADediting_1582927 | chr6_154078830_+ | SINE | Alu | Name=AluJb |
| ADediting_1582928 | chr6_154079727_+ | SINE | Alu | Name=FRAM |
| ADediting_1582929 | chr6_154079753_+ | SINE | Alu | Name=FRAM |
| ADediting_1582930 | chr6_154079779_+ | SINE | Alu | Name=FRAM |
| ADediting_1582931 | chr6_154079837_+ | SINE | Alu | Name=FRAM |
| ADediting_1582932 | chr6_154079844_+ | SINE | Alu | Name=FRAM |
| ADediting_1582933 | chr6_154083833_+ | SINE | Alu | Name=AluY |
| ADediting_1582934 | chr6_154086028_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1582935 | chr6_154086090_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1582936 | chr6_154126958_+ | SINE | Alu | Name=AluSg |
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RNA A-to-I editing events in the alternative splicing sites for OPRM1 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| ES | ADediting_1241682 | chr6_154083709_+ | 154083709:154083717 | 5ss | 3e | AAGGTGGGT | 8.23 | GAGGTGGGT | 7.07 |
| ES | ADediting_1241682 | chr6_154083709_+ | 154083709:154083717 | 5ss | 3e | AAGGTGGGT | 8.23 | GAGGTGGGT | 7.07 |
| ME2 | ADediting_1241682 | chr6_154083709_+ | 154083709:154083717 | 5ss | 3e | AAGGTGGGT | 8.23 | GAGGTGGGT | 7.07 |
| ME2 | ADediting_1241682 | chr6_154083709_+ | 154083709:154083717 | 5ss | 3e | AAGGTGGGT | 8.23 | GAGGTGGGT | 7.07 |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for OPRM1 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for OPRM1 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for OPRM1 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1241702 | chr6_154126856_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-513a-5p | chr6 | 154126850 | 154126856 | 7mer-m8 | 154126840 | 154126857 | 144 | -16.68 |
| ADediting_1241703 | chr6_154126895_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-10a-5p | chr6 | 154126891 | 154126897 | 7mer-m8 | 154126877 | 154126898 | 153 | -21.49 |
| ADediting_1241703 | chr6_154126895_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-10b-5p | chr6 | 154126891 | 154126897 | 7mer-m8 | 154126877 | 154126898 | 145 | -19.48 |
| ADediting_1241703 | chr6_154126895_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-146b-3p | chr6 | 154126890 | 154126896 | 7mer-m8 | 154126878 | 154126897 | 143 | -20.35 |
| ADediting_1241703 | chr6_154126895_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-4725-5p | chr6 | 154126892 | 154126899 | 8mer-1a | 154126879 | 154126899 | 146 | -23 |
| ADediting_1241703 | chr6_154126895_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-504-5p | chr6 | 154126892 | 154126899 | 8mer-1a | 154126876 | 154126899 | 153 | -24.75 |
| ADediting_1241707 | chr6_154126932_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-182-3p | chr6 | 154126929 | 154126935 | 7mer-m8 | 154126913 | 154126936 | 144 | -11.84 |
| ADediting_1241710 | chr6_154126988_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-513a-5p | chr6 | 154126982 | 154126988 | 7mer-m8 | 154126972 | 154126989 | 144 | -17.35 |
| ADediting_1241710 | chr6_154126988_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-638 | chr6 | 154126987 | 154126993 | 7mer-1a | 154126969 | 154126993 | 159 | -33.51 |
| ADediting_1241711 | chr6_154126989_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-8052 | chr6 | 154126987 | 154126993 | 7mer-1a | 154126971 | 154126993 | 143 | -21.76 |
| ADediting_1241712 | chr6_154126998_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-1207-3p | chr6 | 154126991 | 154126997 | 7mer-m8 | 154126981 | 154126998 | 140 | -14.34 |
| ADediting_1241714 | chr6_154127030_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-4267 | chr6 | 154127027 | 154127033 | 7mer-m8 | 154127019 | 154127034 | 142 | -18.58 |
| ADediting_1241715 | chr6_154127037_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-361-3p | chr6 | 154127030 | 154127036 | 7mer-m8 | 154127012 | 154127037 | 157 | -23.85 |
| ADediting_1241717 | chr6_154127094_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-3664-5p | chr6 | 154127088 | 154127094 | 7mer-m8 | 154127073 | 154127095 | 143 | -15.23 |
| ADediting_1241717 | chr6_154127094_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-6794-3p | chr6 | 154127090 | 154127096 | 7mer-m8 | 154127078 | 154127097 | 143 | -18.56 |
| ADediting_1241719 | chr6_154130308_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-17-3p | chr6 | 154130304 | 154130310 | 7mer-m8 | 154130289 | 154130311 | 150 | -22.27 |
| ADediting_1241721 | chr6_154130375_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-3190-5p | chr6 | 154130373 | 154130379 | 7mer-m8 | 154130361 | 154130380 | 147 | -18.19 |
| ADediting_1241721 | chr6_154130375_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-548s | chr6 | 154130372 | 154130378 | 7mer-m8 | 154130357 | 154130379 | 140 | -12.59 |
| ADediting_1582936 | chr6_154126958_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-643 | chr6 | 154126951 | 154126958 | 8mer-1a | 154126936 | 154126958 | 147 | -12.1 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1241702 | chr6_154126856_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-10399-5p | chr6 | 154126851 | 154126857 | 7mer-m8 | 154126837 | 154126858 | 144 | -12.45 |
| ADediting_1241702 | chr6_154126856_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-6504-3p | chr6 | 154126851 | 154126857 | 7mer-m8 | 154126837 | 154126858 | 148 | -14.35 |
| ADediting_1241702 | chr6_154126856_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-7151-3p | chr6 | 154126849 | 154126856 | 8mer-1a | 154126836 | 154126856 | 144 | -16.51 |
| ADediting_1241703 | chr6_154126895_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-581 | chr6 | 154126889 | 154126895 | 7mer-m8 | 154126876 | 154126896 | 151 | -17.32 |
| ADediting_1241705 | chr6_154126923_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-1279 | chr6 | 154126921 | 154126927 | 7mer-m8 | 154126912 | 154126928 | 140 | -8.19 |
| ADediting_1241705 | chr6_154126923_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-4435 | chr6 | 154126916 | 154126923 | 8mer-1a | 154126902 | 154126923 | 140 | -15.03 |
| ADediting_1241708 | chr6_154126934_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-193b-5p | chr6 | 154126931 | 154126938 | 8mer-1a | 154126917 | 154126938 | 146 | -17.17 |
| ADediting_1241708 | chr6_154126934_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-3170 | chr6 | 154126932 | 154126938 | 7mer-m8 | 154126918 | 154126939 | 144 | -13.93 |
| ADediting_1241708 | chr6_154126934_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-6855-5p | chr6 | 154126932 | 154126938 | 7mer-m8 | 154126915 | 154126939 | 145 | -17.81 |
| ADediting_1241709 | chr6_154126962_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-4735-5p | chr6 | 154126956 | 154126962 | 7mer-m8 | 154126942 | 154126963 | 140 | -9.99 |
| ADediting_1241710 | chr6_154126988_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-10399-5p | chr6 | 154126983 | 154126989 | 7mer-m8 | 154126969 | 154126990 | 148 | -10.28 |
| ADediting_1241710 | chr6_154126988_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-6504-3p | chr6 | 154126983 | 154126989 | 7mer-m8 | 154126966 | 154126990 | 144 | -14.13 |
| ADediting_1241710 | chr6_154126988_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-7151-3p | chr6 | 154126981 | 154126988 | 8mer-1a | 154126967 | 154126988 | 143 | -13.09 |
| ADediting_1241711 | chr6_154126989_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-10399-5p | chr6 | 154126983 | 154126989 | 7mer-m8 | 154126969 | 154126990 | 148 | -10.28 |
| ADediting_1241711 | chr6_154126989_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-5089-5p | chr6 | 154126987 | 154126993 | 7mer-m8 | 154126974 | 154126994 | 148 | -16.53 |
| ADediting_1241711 | chr6_154126989_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-6504-3p | chr6 | 154126983 | 154126989 | 7mer-m8 | 154126966 | 154126990 | 144 | -14.13 |
| ADediting_1241712 | chr6_154126998_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-4661-5p | chr6 | 154126993 | 154126999 | 7mer-m8 | 154126982 | 154127000 | 143 | -12.9 |
| ADediting_1241713 | chr6_154127015_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-1976 | chr6 | 154127012 | 154127019 | 8mer-1a | 154126999 | 154127019 | 149 | -24.39 |
| ADediting_1241713 | chr6_154127015_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-6747-3p | chr6 | 154127010 | 154127017 | 8mer-1a | 154126995 | 154127017 | 153 | -23.85 |
| ADediting_1241714 | chr6_154127030_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-498-5p | chr6 | 154127023 | 154127029 | 7mer-m8 | 154127008 | 154127030 | 142 | -10.65 |
| ADediting_1241715 | chr6_154127037_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-1281 | chr6 | 154127034 | 154127040 | 7mer-m8 | 154127025 | 154127041 | 147 | -20.07 |
| ADediting_1241715 | chr6_154127037_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-2355-5p | chr6 | 154127030 | 154127036 | 7mer-m8 | 154127018 | 154127037 | 148 | -14.91 |
| ADediting_1241715 | chr6_154127037_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-6778-3p | chr6 | 154127033 | 154127039 | 7mer-m8 | 154127022 | 154127040 | 143 | -18.25 |
| ADediting_1241716 | chr6_154127044_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-718 | chr6 | 154127037 | 154127043 | 7mer-m8 | 154127024 | 154127044 | 155 | -30.09 |
| ADediting_1241716 | chr6_154127044_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-891b | chr6 | 154127042 | 154127049 | 8mer-1a | 154127027 | 154127049 | 143 | -16.45 |
| ADediting_1241717 | chr6_154127094_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-4652-3p | chr6 | 154127087 | 154127093 | 7mer-m8 | 154127074 | 154127094 | 148 | -13.88 |
| ADediting_1241717 | chr6_154127094_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-4778-5p | chr6 | 154127088 | 154127094 | 7mer-m8 | 154127074 | 154127095 | 140 | -11.98 |
| ADediting_1241717 | chr6_154127094_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-6758-3p | chr6 | 154127091 | 154127098 | 8mer-1a | 154127081 | 154127098 | 150 | -20.74 |
| ADediting_1241718 | chr6_154130232_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-6807-5p | chr6 | 154130225 | 154130232 | 8mer-1a | 154130211 | 154130232 | 155 | -17.17 |
| ADediting_1241719 | chr6_154130308_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-20b-3p | chr6 | 154130304 | 154130310 | 7mer-m8 | 154130289 | 154130311 | 153 | -18.04 |
| ADediting_1241720 | chr6_154130353_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-3675-3p | chr6 | 154130351 | 154130357 | 7mer-m8 | 154130337 | 154130358 | 145 | -12.58 |
| ADediting_1241721 | chr6_154130375_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-4794 | chr6 | 154130373 | 154130379 | 7mer-m8 | 154130358 | 154130380 | 151 | -18.08 |
| ADediting_1241721 | chr6_154130375_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-664a-5p | chr6 | 154130373 | 154130379 | 7mer-m8 | 154130357 | 154130380 | 143 | -16.43 |
| ADediting_1582936 | chr6_154126958_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-4735-5p | chr6 | 154126956 | 154126962 | 7mer-m8 | 154126942 | 154126963 | 140 | -9.99 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1241682 | chr6_154083709_+ | ENSG00000112038.18 | ENST00000519613.5 | OPRM1-213 | hsa-miR-6878-3p | chr6 | 154083703 | 154083710 | 8mer-1a | 154083690 | 154083710 | 142 | -16.41 |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-5688 | chr6 | 154127493 | 154127500 | 8mer-1a | 154127479 | 154127500 | 145 | -14.21 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-589-3p | chr6 | 154118869 | 154118875 | 7mer-m8 | 154118851 | 154118876 | 150 | -18.32 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-589-3p | chr6 | 154126693 | 154126699 | 7mer-m8 | 154126677 | 154126700 | 140 | -14.41 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-589-3p | chr6 | 154127892 | 154127898 | 7mer-m8 | 154127876 | 154127899 | 140 | -17.56 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-589-3p | chr6 | 154131063 | 154131069 | 7mer-m8 | 154131047 | 154131070 | 140 | -14.41 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-589-3p | chr6 | 154131531 | 154131537 | 7mer-m8 | 154131515 | 154131538 | 140 | -13.65 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000112038.18 | ENST00000522236.1 | OPRM1-217 | hsa-miR-589-3p | chr6 | 154118869 | 154118875 | 7mer-m8 | 154118851 | 154118876 | 150 | -18.32 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000112038.18 | ENST00000522555.5 | OPRM1-219 | hsa-miR-589-3p | chr6 | 154118869 | 154118875 | 7mer-m8 | 154118851 | 154118876 | 150 | -18.32 |
| ADediting_1337758 | chr7_5495892_- | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-589-5p | chr6 | 154126520 | 154126526 | 7mer-m8 | 154126506 | 154126527 | 147 | -17.16 |
| ADediting_1337758 | chr7_5495892_- | ENSG00000112038.18 | ENST00000414028.6 | OPRM1-205 | hsa-miR-589-5p | chr6 | 154108082 | 154108088 | 7mer-m8 | 154108065 | 154108089 | 151 | -21.38 |
| ADediting_1337758 | chr7_5495892_- | ENSG00000112038.18 | ENST00000435918.6 | OPRM1-209 | hsa-miR-589-5p | chr6 | 154108082 | 154108088 | 7mer-m8 | 154108065 | 154108089 | 151 | -21.38 |
| ADediting_1535951 | chr14_100874558_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-337-3p | chr6 | 154124983 | 154124989 | 7mer-m8 | 154124969 | 154124990 | 144 | -11.65 |
| ADediting_1535953 | chr14_101045971_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-381-3p | chr6 | 154128854 | 154128860 | 7mer-1a | 154128838 | 154128860 | 147 | -18.54 |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-381-3p | chr6 | 154129414 | 154129420 | 7mer-m8 | 154129398 | 154129421 | 148 | -19.85 |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-381-3p | chr6 | 154131812 | 154131818 | 7mer-m8 | 154131798 | 154131819 | 140 | -15.8 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-641 | chr6 | 154126496 | 154126503 | 8mer-1a | 154126480 | 154126503 | 144 | -12.03 |
| ADediting_1596844 | chr1_162342605_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-556-3p | chr6 | 154130859 | 154130865 | 7mer-m8 | 154130845 | 154130866 | 145 | -8.56 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-641 | chr6 | 154131150 | 154131156 | 7mer-m8 | 154131134 | 154131157 | 140 | -11.21 |
| ADediting_286380 | chr11_79422188_- | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-5579-3p | chr6 | 154123263 | 154123269 | 7mer-m8 | 154123249 | 154123270 | 147 | -15.29 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-4775 | chr6 | 154124445 | 154124451 | 7mer-m8 | 154124427 | 154124452 | 154 | -7.28 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-4775 | chr6 | 154129561 | 154129567 | 7mer-m8 | 154129547 | 154129568 | 166 | -17.47 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-4775 | chr6 | 154131238 | 154131245 | 8mer-1a | 154131223 | 154131245 | 160 | -16.92 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-5585-3p | chr6 | 154121586 | 154121592 | 7mer-m8 | 154121572 | 154121593 | 144 | -10.78 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000112038.18 | ENST00000414028.6 | OPRM1-205 | hsa-miR-5585-3p | chr6 | 154107991 | 154107997 | 7mer-m8 | 154107976 | 154107998 | 151 | -10.55 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-5688 | chr6 | 154123251 | 154123257 | 7mer-m8 | 154123236 | 154123258 | 155 | -13.15 |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-5688 | chr6 | 154127455 | 154127461 | 7mer-m8 | 154127440 | 154127462 | 155 | -13.68 |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-5688 | chr6 | 154131847 | 154131853 | 7mer-m8 | 154131834 | 154131854 | 149 | -11.07 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-589-3p | chr6 | 154127235 | 154127242 | 8mer-1a | 154127220 | 154127242 | 143 | -13.55 |
| ADediting_1337758 | chr7_5495892_- | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-589-5p | chr6 | 154126749 | 154126755 | 7mer-m8 | 154126735 | 154126756 | 140 | -12.55 |
| ADediting_1535951 | chr14_100874558_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-337-3p | chr6 | 154126181 | 154126187 | 7mer-m8 | 154126167 | 154126188 | 145 | -14.87 |
| ADediting_1535951 | chr14_100874558_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-337-3p | chr6 | 154128995 | 154129002 | 8mer-1a | 154128981 | 154129002 | 141 | -8.17 |
| ADediting_1596844 | chr1_162342605_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-556-3p | chr6 | 154119507 | 154119513 | 7mer-m8 | 154119493 | 154119514 | 149 | -7.25 |
| ADediting_1596844 | chr1_162342605_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-556-3p | chr6 | 154128790 | 154128796 | 7mer-m8 | 154128773 | 154128797 | 146 | -12.31 |
| ADediting_291761 | chr11_93733708_- | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-1304-3p | chr6 | 154131733 | 154131739 | 7mer-m8 | 154131719 | 154131740 | 148 | -14.22 |
| ADediting_291761 | chr11_93733708_- | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-1304-3p | chr6 | 154132153 | 154132159 | 7mer-m8 | 154132139 | 154132160 | 145 | -12.85 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-4775 | chr6 | 154119220 | 154119226 | 7mer-m8 | 154119206 | 154119227 | 148 | -4.93 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-4775 | chr6 | 154122977 | 154122984 | 8mer-1a | 154122960 | 154122984 | 154 | -8.22 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-4775 | chr6 | 154124219 | 154124226 | 8mer-1a | 154124203 | 154124226 | 152 | -10.43 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-4775 | chr6 | 154128889 | 154128895 | 7mer-1a | 154128874 | 154128895 | 150 | -12.08 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000112038.18 | ENST00000414028.6 | OPRM1-205 | hsa-miR-4775 | chr6 | 154108869 | 154108876 | 8mer-1a | 154108855 | 154108876 | 140 | -7.94 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000112038.18 | ENST00000428397.6 | OPRM1-207 | hsa-miR-4775 | chr6 | 154091516 | 154091522 | 7mer-m8 | 154091500 | 154091523 | 153 | -9.81 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000112038.18 | ENST00000435918.6 | OPRM1-209 | hsa-miR-4775 | chr6 | 154108869 | 154108876 | 8mer-1a | 154108855 | 154108876 | 140 | -7.94 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-5585-3p | chr6 | 154124015 | 154124022 | 8mer-1a | 154123998 | 154124022 | 148 | -16.12 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-5585-3p | chr6 | 154124940 | 154124947 | 8mer-1a | 154124928 | 154124947 | 151 | -11.51 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-5585-3p | chr6 | 154124015 | 154124022 | 8mer-1a | 154123998 | 154124022 | 148 | -16.12 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000112038.18 | ENST00000330432.12 | OPRM1-202 | hsa-miR-5585-3p | chr6 | 154124940 | 154124947 | 8mer-1a | 154124928 | 154124947 | 151 | -11.51 |
| Differentially expressed gene-miRNA network |
| Differentially expressed mRNA-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for OPRM1 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000330432.12 | protein_coding |  |  |
| ENST00000523520.1 | lncRNA |  |  |
| ENST00000519613.5 | lncRNA |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_1241702 | ENST00000330432.12 | chr6_154126856_+ | 9643 | -4231.47 | -4231.37 | -4263.20 |
| ADediting_1241703 | ENST00000330432.12 | chr6_154126895_+ | 9682 | -4231.27 | -4231.37 | -4263.20 |
| ADediting_1241704 | ENST00000330432.12 | chr6_154126908_+ | 9695 | -4237.37 | -4231.37 | -4263.20 |
| ADediting_1241705 | ENST00000330432.12 | chr6_154126923_+ | 9710 | -4231.77 | -4231.37 | -4263.20 |
| ADediting_1241706 | ENST00000330432.12 | chr6_154126931_+ | 9718 | -4237.77 | -4231.37 | -4263.20 |
| ADediting_1241707 | ENST00000330432.12 | chr6_154126932_+ | 9719 | -4231.77 | -4231.37 | -4263.20 |
| ADediting_1241708 | ENST00000330432.12 | chr6_154126934_+ | 9721 | -4231.37 | -4231.37 | -4263.20 |
| ADediting_1582936 | ENST00000330432.12 | chr6_154126958_+ | 9745 | -4231.77 | -4231.37 | -4263.20 |
| ADediting_1241709 | ENST00000330432.12 | chr6_154126962_+ | 9749 | -4231.07 | -4231.37 | -4263.20 |
| ADediting_1241710 | ENST00000330432.12 | chr6_154126988_+ | 9775 | -4231.07 | -4231.37 | -4263.20 |
| ADediting_1241711 | ENST00000330432.12 | chr6_154126989_+ | 9776 | -4237.57 | -4231.37 | -4263.20 |
| ADediting_1241712 | ENST00000330432.12 | chr6_154126998_+ | 9785 | -4231.07 | -4231.37 | -4263.20 |
| ADediting_1241713 | ENST00000330432.12 | chr6_154127015_+ | 9802 | -4230.67 | -4231.37 | -4263.20 |
| ADediting_1241714 | ENST00000330432.12 | chr6_154127030_+ | 9817 | -4231.37 | -4231.37 | -4263.20 |
| ADediting_1241715 | ENST00000330432.12 | chr6_154127037_+ | 9824 | -4230.47 | -4231.37 | -4263.20 |
| ADediting_1241716 | ENST00000330432.12 | chr6_154127044_+ | 9831 | -4235.77 | -4231.37 | -4263.20 |
| ADediting_1241717 | ENST00000330432.12 | chr6_154127094_+ | 9881 | -4237.87 | -4231.37 | -4263.20 |
| ADediting_1241718 | ENST00000330432.12 | chr6_154130232_+ | 13019 | -4230.97 | -4231.37 | -4263.20 |
| ADediting_1241719 | ENST00000330432.12 | chr6_154130308_+ | 13095 | -4231.37 | -4231.37 | -4263.20 |
| ADediting_1241720 | ENST00000330432.12 | chr6_154130353_+ | 13140 | -4231.07 | -4231.37 | -4263.20 |
| ADediting_1241721 | ENST00000330432.12 | chr6_154130375_+ | 13162 | -4235.17 | -4231.37 | -4263.20 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_1582916 | ENST00000523520.1 | chr6_154073787_+ | 866 | -481.60 | -481.60 | -481.60 |
| ADediting_1241682 | ENST00000519613.5 | chr6_154083709_+ | 220 | -309.50 | -310.20 | -309.50 |
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Relation with ADAR for OPRM1 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_1241681 | chr6_154078785_+ | 8.3532658178588e-05 | 0.315603623452359 | 0.000369133951328313 | 0.287030625487996 | 0.607569293179367 | -0.0422656998062782 |
| CER | ADediting_1241703 | chr6_154126895_+ | 0.000325686116234495 | 0.289556186498359 | 6.3154235536688e-07 | 0.39348501839422 | 0.0995578841879848 | 0.134990053668253 |
| CER | ADediting_1241704 | chr6_154126908_+ | 3.51210313241903e-05 | 0.331015561223068 | 4.77735298496238e-08 | 0.427727267079278 | 0.0216407465633647 | 0.187420843000239 |
| CER | ADediting_1241706 | chr6_154126931_+ | 7.56537432438172e-05 | 0.317408666007856 | 2.61812103873394e-06 | 0.372841404211884 | 0.00150797222924385 | 0.256873442645827 |
| CER | ADediting_1241707 | chr6_154126932_+ | 9.88880977431741e-05 | 0.312502235349065 | 8.56581069787085e-07 | 0.389177481766337 | 0.0244884719866598 | 0.183632409630942 |
| CER | ADediting_1241708 | chr6_154126934_+ | 0.00285378421309219 | 0.241960476546372 | 1.24146528329188e-05 | 0.348487937412744 | 0.0137541936741071 | 0.200780549747862 |
| CER | ADediting_1241711 | chr6_154126989_+ | 5.57989968937876e-09 | 0.453572017251185 | 6.14202432000569e-15 | 0.581400378247139 | 0.000156500614982696 | 0.30388778433834 |
| TCX | ADediting_1241711 | chr6_154126989_+ | 0.00114178100937628 | 0.263114492711581 | 7.67476571803111e-07 | 0.39073691829924 | 0.484772104049412 | -0.0574780072073764 |
| CER | ADediting_1241712 | chr6_154126998_+ | 4.10563065009151e-05 | 0.328298713537262 | 4.01252220647775e-10 | 0.482574176009198 | 0.000456682513415704 | 0.282683561029925 |
| CER | ADediting_1241716 | chr6_154127044_+ | 0.00330100018814066 | 0.238429600605054 | 1.95866012821604e-05 | 0.34095565321292 | 0.0349184337183976 | 0.172374553596727 |
| CER | ADediting_1241717 | chr6_154127094_+ | 0.000153854332951381 | 0.304212588765889 | 4.5180146070938e-06 | 0.364529189499952 | 0.0627870312414454 | 0.152311745424703 |
| CER | ADediting_1241718 | chr6_154130232_+ | 0.000141707280249751 | 0.305773691572371 | 2.15260635742283e-08 | 0.437575629771484 | 0.00542128658567284 | 0.226002553825526 |
| TCX | ADediting_1241718 | chr6_154130232_+ | 0.104501214381552 | 0.133074101645601 | 3.10894442161456e-07 | 0.403271971475975 | 0.129409055865334 | -0.124375684274072 |
| CER | ADediting_1241719 | chr6_154130308_+ | 6.7941542168491e-05 | 0.319354722379684 | 2.35287425973652e-08 | 0.436492076806956 | 0.00489007403460623 | 0.228638333017317 |
| CER | ADediting_1241720 | chr6_154130353_+ | 0.00156685408472765 | 0.256002140670598 | 4.65615640105449e-05 | 0.326090464713011 | 0.2778477339032 | 0.0891728338332803 |
| CER | ADediting_1241721 | chr6_154130375_+ | 1.92542477409666e-05 | 0.341241899410541 | 1.35939538287859e-09 | 0.469466125122174 | 0.0157433904986875 | 0.196881647376912 |
| TCX | ADediting_1241721 | chr6_154130375_+ | 0.184495972630525 | 0.108940791887315 | 6.45877295347361e-07 | 0.393169880674944 | 0.144290781550176 | -0.119780687596379 |
| CER | ADediting_1582926 | chr6_154078813_+ | 6.00652962587073e-05 | 0.321568613296819 | 0.00116869805440792 | 0.262597443410671 | 0.142206162791142 | -0.120401903453871 |
| CER | ADediting_1582927 | chr6_154078830_+ | 1.32774064041396e-05 | 0.347390159416306 | 0.000862245346019456 | 0.269266434260524 | 0.85724063327022 | -0.0148108737960236 |
| CER | ADediting_1582930 | chr6_154079779_+ | 0.000147185956924276 | 0.30505474123534 | 0.00699489827483249 | 0.219362430767524 | 0.513242688170225 | 0.0537936275488437 |
| CER | ADediting_1582932 | chr6_154079844_+ | 0.000110408668861826 | 0.310458355563586 | 0.0230763978471949 | 0.185460667206601 | 0.681187818270707 | -0.0338184814686375 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 7.067424315248e-14 | 0.408195254610041 | 6.87873992134885e-06 | 0.252310222626461 | 0.00116352452896153 | 0.183626404282425 |
| AC | 0.564725849146176 | 0.0365902590930569 | 0.487146887126422 | 0.0441462269754701 | 3.87249539090729e-08 | -0.338985239502088 |
| CER | 5.00891189206369e-18 | 0.630905566183893 | 1.39508067734363e-23 | 0.702058260229102 | 0.0037708793246984 | 0.235157279218529 |
| TCX | 1.20394878102696e-17 | 0.625249812028302 | 5.04231401330835e-49 | 0.877240565947756 | 0.00202085235727244 | -0.25013772593578 |
| FP | 1.37658279718644e-25 | 0.680870775900245 | 1.70141894068236e-37 | 0.778846348111299 | 0.186127584928588 | 0.0995522354826572 |
| IFG | 5.71412925597646e-06 | 0.773741641645759 | 2.12400129945435e-05 | 0.742659563027025 | 0.588588614979354 | 0.113643093038819 |
| PG | 1.27916714009478e-46 | 0.820789459796066 | 5.61247463316795e-38 | 0.771472483064821 | 0.134510384568465 | -0.110140738112286 |
| STG | 5.03320900706177e-09 | 0.585199012133137 | 3.30905545371885e-11 | 0.645740183535629 | 0.461123918402029 | -0.0815002901718516 |
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Relation with AD stages for OPRM1 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_1241711 | chr6_154126989_+ | 3.97474011319814e-07 | 0.465003881862113 |
| CER | ADediting_1241712 | chr6_154126998_+ | 0.000320603685668641 | 0.339815076367951 |
| CER | ADediting_1241716 | chr6_154127044_+ | 0.000207902750978603 | 0.349653422456809 |
| CER | ADediting_1241718 | chr6_154130232_+ | 0.00107419558569443 | 0.310485942454562 |
| CER | ADediting_1241719 | chr6_154130308_+ | 0.000595609817827189 | 0.32515668649319 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 0.000257677439611588 | 0.344818430198165 |
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RelatedDrugs for OPRM1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| OPRM1 | P35372 | DB00321 | Amitriptyline | Mu-type opioid receptor | small molecule | approved |
| OPRM1 | P35372 | DB00333 | Methadone | Mu-type opioid receptor | small molecule | approved |
| OPRM1 | P35372 | DB00454 | Meperidine | Mu-type opioid receptor | small molecule | approved |
| OPRM1 | P35372 | DB00514 | Dextromethorphan | Mu-type opioid receptor | small molecule | approved |
| OPRM1 | P35372 | DB00836 | Loperamide | Mu-type opioid receptor | small molecule | approved |
| OPRM1 | P35372 | DB00844 | Nalbuphine | Mu-type opioid receptor | small molecule | approved |
| OPRM1 | P35372 | DB00899 | Remifentanil | Mu-type opioid receptor | small molecule | approved |
| OPRM1 | P35372 | DB00904 | Ondansetron | Mu-type opioid receptor | small molecule | approved |
| OPRM1 | P35372 | DB06204 | Tapentadol | Mu-type opioid receptor | small molecule | approved |
| OPRM1 | P35372 | DB06800 | Methylnaltrexone | Mu-type opioid receptor | small molecule | approved |
| OPRM1 | P35372 | DB09049 | Naloxegol | Mu-type opioid receptor | small molecule | approved |
| OPRM1 | P35372 | DB09089 | Trimebutine | Mu-type opioid receptor | small molecule | approved |
| OPRM1 | P35372 | DB00318 | Codeine | Mu-type opioid receptor | small molecule | approved|illicit |
| OPRM1 | P35372 | DB00327 | Hydromorphone | Mu-type opioid receptor | small molecule | approved|illicit |
| OPRM1 | P35372 | DB00802 | Alfentanil | Mu-type opioid receptor | small molecule | approved|illicit |
| OPRM1 | P35372 | DB00913 | Anileridine | Mu-type opioid receptor | small molecule | approved|illicit |
| OPRM1 | P35372 | DB01081 | Diphenoxylate | Mu-type opioid receptor | small molecule | approved|illicit |
| OPRM1 | P35372 | DB09209 | Pholcodine | Mu-type opioid receptor | small molecule | approved|illicit |
| OPRM1 | P35372 | DB11130 | Opium | Mu-type opioid receptor | small molecule | approved|illicit |
| OPRM1 | P35372 | DB00497 | Oxycodone | Mu-type opioid receptor | small molecule | approved|illicit|investigational |
| OPRM1 | P35372 | DB00956 | Hydrocodone | Mu-type opioid receptor | small molecule | approved|illicit|investigational |
| OPRM1 | P35372 | DB01452 | Diamorphine | Mu-type opioid receptor | small molecule | approved|illicit|investigational |
| OPRM1 | P35372 | DB00813 | Fentanyl | Mu-type opioid receptor | small molecule | approved|illicit|investigational|vet_approved |
| OPRM1 | P35372 | DB00921 | Buprenorphine | Mu-type opioid receptor | small molecule | approved|illicit|investigational|vet_approved |
| OPRM1 | P35372 | DB00647 | Dextropropoxyphene | Mu-type opioid receptor | small molecule | approved|illicit|investigational|withdrawn |
| OPRM1 | P35372 | DB00611 | Butorphanol | Mu-type opioid receptor | small molecule | approved|illicit|vet_approved |
| OPRM1 | P35372 | DB00193 | Tramadol | Mu-type opioid receptor | small molecule | approved|investigational |
| OPRM1 | P35372 | DB00295 | Morphine | Mu-type opioid receptor | small molecule | approved|investigational |
| OPRM1 | P35372 | DB00708 | Sufentanil | Mu-type opioid receptor | small molecule | approved|investigational |
| OPRM1 | P35372 | DB01209 | Dezocine | Mu-type opioid receptor | small molecule | approved|investigational |
| OPRM1 | P35372 | DB01227 | Levacetylmethadol | Mu-type opioid receptor | small molecule | approved|investigational |
| OPRM1 | P35372 | DB06274 | Alvimopan | Mu-type opioid receptor | small molecule | approved|investigational |
| OPRM1 | P35372 | DB09061 | Cannabidiol | Mu-type opioid receptor | small molecule | approved|investigational |
| OPRM1 | P35372 | DB09272 | Eluxadoline | Mu-type opioid receptor | small molecule | approved|investigational |
| OPRM1 | P35372 | DB11186 | Pentoxyverine | Mu-type opioid receptor | small molecule | approved|investigational |
| OPRM1 | P35372 | DB11691 | Naldemedine | Mu-type opioid receptor | small molecule | approved|investigational |
| OPRM1 | P35372 | DB00704 | Naltrexone | Mu-type opioid receptor | small molecule | approved|investigational|vet_approved |
| OPRM1 | P35372 | DB06230 | Nalmefene | Mu-type opioid receptor | small molecule | approved|investigational|withdrawn |
| OPRM1 | P35372 | DB00652 | Pentazocine | Mu-type opioid receptor | small molecule | approved|vet_approved |
| OPRM1 | P35372 | DB01183 | Naloxone | Mu-type opioid receptor | small molecule | approved|vet_approved |
| OPRM1 | P35372 | DB01221 | Ketamine | Mu-type opioid receptor | small molecule | approved|vet_approved |
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RelatedDiseases for OPRM1 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| OPRM1 | C0001973 | Alcoholic Intoxication, Chronic | 6 | CTD_human;PSYGENET |
| OPRM1 | C0600427 | Cocaine Dependence | 6 | CTD_human;PSYGENET |
| OPRM1 | C0001969 | Alcoholic Intoxication | 5 | PSYGENET |
| OPRM1 | C0011570 | Mental Depression | 4 | PSYGENET |
| OPRM1 | C0011581 | Depressive disorder | 4 | PSYGENET |
| OPRM1 | C0009171 | Cocaine Abuse | 3 | CTD_human |
| OPRM1 | C0036341 | Schizophrenia | 3 | PSYGENET |
| OPRM1 | C0085762 | Alcohol abuse | 3 | CTD_human;PSYGENET |
| OPRM1 | C0236736 | Cocaine-Related Disorders | 3 | CTD_human |
| OPRM1 | C0019196 | Hepatitis C | 2 | CTD_human |
| OPRM1 | C0022333 | Jacksonian Seizure | 2 | CTD_human |
| OPRM1 | C0027796 | Neuralgia | 2 | CTD_human |
| OPRM1 | C0033975 | Psychotic Disorders | 2 | PSYGENET |
| OPRM1 | C0036572 | Seizures | 2 | CTD_human |
| OPRM1 | C0038870 | Neuralgia, Supraorbital | 2 | CTD_human |
| OPRM1 | C0042656 | Neuralgia, Vidian | 2 | CTD_human |
| OPRM1 | C0149958 | Complex partial seizures | 2 | CTD_human |
| OPRM1 | C0234247 | Neuralgia, Atypical | 2 | CTD_human |
| OPRM1 | C0234249 | Neuralgia, Stump | 2 | CTD_human |
| OPRM1 | C0234533 | Generalized seizures | 2 | CTD_human |
| OPRM1 | C0234535 | Seizures, Clonic | 2 | CTD_human |
| OPRM1 | C0270824 | Visual seizure | 2 | CTD_human |
| OPRM1 | C0270844 | Tonic Seizures | 2 | CTD_human |
| OPRM1 | C0270846 | Epileptic drop attack | 2 | CTD_human |
| OPRM1 | C0349204 | Nonorganic psychosis | 2 | PSYGENET |
| OPRM1 | C0422850 | Seizures, Somatosensory | 2 | CTD_human |
| OPRM1 | C0422852 | Seizures, Auditory | 2 | CTD_human |
| OPRM1 | C0422853 | Olfactory seizure | 2 | CTD_human |
| OPRM1 | C0422854 | Gustatory seizure | 2 | CTD_human |
| OPRM1 | C0422855 | Vertiginous seizure | 2 | CTD_human |
| OPRM1 | C0423711 | Neuralgia, Perineal | 2 | CTD_human |
| OPRM1 | C0423712 | Neuralgia, Iliohypogastric Nerve | 2 | CTD_human |
| OPRM1 | C0494475 | Tonic - clonic seizures | 2 | CTD_human |
| OPRM1 | C0751056 | Non-epileptic convulsion | 2 | CTD_human |
| OPRM1 | C0751110 | Single Seizure | 2 | CTD_human |
| OPRM1 | C0751123 | Atonic Absence Seizures | 2 | CTD_human |
| OPRM1 | C0751371 | Neuralgia, Ilioinguinal | 2 | CTD_human |
| OPRM1 | C0751372 | Nerve Pain | 2 | CTD_human |
| OPRM1 | C0751373 | Paroxysmal Nerve Pain | 2 | CTD_human |
| OPRM1 | C0751494 | Convulsive Seizures | 2 | CTD_human |
| OPRM1 | C0751495 | Seizures, Focal | 2 | CTD_human |
| OPRM1 | C0751496 | Seizures, Sensory | 2 | CTD_human |
| OPRM1 | C3495874 | Nonepileptic Seizures | 2 | CTD_human |
| OPRM1 | C4048158 | Convulsions | 2 | CTD_human |
| OPRM1 | C4316903 | Absence Seizures | 2 | CTD_human |
| OPRM1 | C4317109 | Epileptic Seizures | 2 | CTD_human |
| OPRM1 | C4317123 | Myoclonic Seizures | 2 | CTD_human |
| OPRM1 | C4505436 | Generalized Absence Seizures | 2 | CTD_human |
| OPRM1 | C0001849 | AIDS Dementia Complex | 1 | CTD_human |
| OPRM1 | C0001956 | Alcohol Use Disorder | 1 | CTD_human |
| OPRM1 | C0009806 | Constipation | 1 | CTD_human |
| OPRM1 | C0013146 | Drug abuse | 1 | CTD_human |
| OPRM1 | C0013170 | Drug habituation | 1 | CTD_human |
| OPRM1 | C0013222 | Drug Use Disorders | 1 | CTD_human |
| OPRM1 | C0013384 | Dyskinetic syndrome | 1 | CTD_human |
| OPRM1 | C0014544 | Epilepsy | 1 | CTD_human |
| OPRM1 | C0019147 | Hepatic Coma | 1 | CTD_human |
| OPRM1 | C0019151 | Hepatic Encephalopathy | 1 | CTD_human |
| OPRM1 | C0019337 | Heroin Dependence | 1 | CTD_human |
| OPRM1 | C0020429 | Hyperalgesia | 1 | CTD_human |
| OPRM1 | C0020651 | Hypotension, Orthostatic | 1 | CTD_human |
| OPRM1 | C0026552 | Morphine Dependence | 1 | CTD_human |
| OPRM1 | C0026650 | Movement Disorders | 1 | CTD_human |
| OPRM1 | C0027497 | Nausea | 1 | CTD_human |
| OPRM1 | C0029231 | Organic Mental Disorders, Substance-Induced | 1 | CTD_human |
| OPRM1 | C0033774 | Pruritus | 1 | CTD_human |
| OPRM1 | C0033937 | Psychoses, Drug | 1 | CTD_human |
| OPRM1 | C0033941 | Psychoses, Substance-Induced | 1 | CTD_human |
| OPRM1 | C0035229 | Respiratory Insufficiency | 1 | CTD_human |
| OPRM1 | C0038580 | Substance Dependence | 1 | CTD_human |
| OPRM1 | C0038586 | Substance Use Disorders | 1 | CTD_human |
| OPRM1 | C0086237 | Epilepsy, Cryptogenic | 1 | CTD_human |
| OPRM1 | C0152115 | Lingual-Facial-Buccal Dyskinesia | 1 | CTD_human |
| OPRM1 | C0206019 | HIV Encephalopathy | 1 | CTD_human |
| OPRM1 | C0221074 | Depression, Postpartum | 1 | PSYGENET |
| OPRM1 | C0221169 | Hemiballismus | 1 | CTD_human |
| OPRM1 | C0232766 | Asterixis | 1 | CTD_human |
| OPRM1 | C0233477 | Dysphoric mood | 1 | PSYGENET |
| OPRM1 | C0235063 | Respiratory Depression | 1 | CTD_human |
| OPRM1 | C0236018 | Aura | 1 | CTD_human |
| OPRM1 | C0236733 | Amphetamine-Related Disorders | 1 | CTD_human |
| OPRM1 | C0236804 | Amphetamine Addiction | 1 | CTD_human |
| OPRM1 | C0236807 | Amphetamine Abuse | 1 | CTD_human |
| OPRM1 | C0236969 | Substance-Related Disorders | 1 | CTD_human |
| OPRM1 | C0237326 | Dyschezia | 1 | CTD_human |
| OPRM1 | C0243010 | Viral Encephalitis | 1 | CTD_human |
| OPRM1 | C0266487 | Etat Marbre | 1 | CTD_human |
| OPRM1 | C0427086 | Involuntary Movements | 1 | CTD_human |
| OPRM1 | C0454606 | Oral Dyskinesia | 1 | CTD_human |
| OPRM1 | C0458247 | Allodynia | 1 | CTD_human |
| OPRM1 | C0600272 | Morphine Abuse | 1 | CTD_human |
| OPRM1 | C0740858 | Substance abuse problem | 1 | CTD_human |
| OPRM1 | C0751111 | Awakening Epilepsy | 1 | CTD_human |
| OPRM1 | C0751197 | Fulminant Hepatic Failure with Cerebral Edema | 1 | CTD_human |
| OPRM1 | C0751198 | Hepatic Stupor | 1 | CTD_human |
| OPRM1 | C0751211 | Hyperalgesia, Primary | 1 | CTD_human |
| OPRM1 | C0751212 | Hyperalgesia, Secondary | 1 | CTD_human |
| OPRM1 | C0751213 | Tactile Allodynia | 1 | CTD_human |
| OPRM1 | C0751214 | Hyperalgesia, Thermal | 1 | CTD_human |
| OPRM1 | C0752196 | Ballismus | 1 | CTD_human |
| OPRM1 | C0936243 | HIV-1-Associated Cognitive Motor Complex | 1 | CTD_human |
| OPRM1 | C1145670 | Respiratory Failure | 1 | CTD_human |
| OPRM1 | C1257861 | Colonic Inertia | 1 | CTD_human |
| OPRM1 | C1510472 | Drug Dependence | 1 | CTD_human |
| OPRM1 | C1837893 | SCHIZOPHRENIA 12 | 1 | PSYGENET |
| OPRM1 | C2936719 | Mechanical Allodynia | 1 | CTD_human |
| OPRM1 | C4316881 | Prescription Drug Abuse | 1 | CTD_human |
| OPRM1 | C4505390 | Heroin Smoking | 1 | CTD_human |
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