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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

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Protein coding region RNA A-to-I editings

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The effects of the RNA editing to the miRNA binding sites

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The effects of the RNA editing to the stability of the RNA structures

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Relation with ADAR

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Relation with AD stages

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Related drugs with this gene

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Related diseases with this gene


Gene summary for HCG11

check button Gene summary
Gene informationGene symbol

HCG11

Gene ID

493812

Gene nameHLA complex group 11
SynonymsCTA-14H9.3|bK14H9.3
Cytomap

6p22.2

Type of genencRNA
DescriptionHLA complex group 11 (non-protein coding)
Modification date20200313
UniProtAcc

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for HCG11

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_1253581(26525384, +), ADediting_1253582(26525385, +), ADediting_1253583(26525415, +), ADediting_1253584(26525424, +), ADediting_1253585(26525429, +), ADediting_1253586(26525451, +), ADediting_1253587(26525452, +), ADediting_1253588(26525491, +), ADediting_1253589(26525527, +), ADediting_1253590(26525544, +), ADediting_1253591(26525582, +), ADediting_1253592(26525583, +), ADediting_1253593(26526353, +),

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RNA editing positional annotations for HCG11 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_1253581chr6_26525384_+ncRNA_exonic
ADediting_1253582chr6_26525385_+ncRNA_exonic
ADediting_1253583chr6_26525415_+ncRNA_exonic
ADediting_1253584chr6_26525424_+ncRNA_exonic
ADediting_1253585chr6_26525429_+ncRNA_exonic
ADediting_1253586chr6_26525451_+ncRNA_exonic
ADediting_1253587chr6_26525452_+ncRNA_exonic
ADediting_1253588chr6_26525491_+ncRNA_exonic
ADediting_1253589chr6_26525527_+ncRNA_exonic
ADediting_1253590chr6_26525544_+ncRNA_exonic
ADediting_1253591chr6_26525582_+ncRNA_exonic
ADediting_1253592chr6_26525583_+ncRNA_exonic
ADediting_1253593chr6_26526353_+ncRNA_exonic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_1253581chr6_26525384_+SINEAluName=AluSc
ADediting_1253582chr6_26525385_+SINEAluName=AluSc
ADediting_1253583chr6_26525415_+SINEAluName=AluSc
ADediting_1253584chr6_26525424_+SINEAluName=AluSc
ADediting_1253585chr6_26525429_+SINEAluName=AluSc
ADediting_1253586chr6_26525451_+SINEAluName=AluSc
ADediting_1253587chr6_26525452_+SINEAluName=AluSc
ADediting_1253588chr6_26525491_+SINEAluName=AluSc
ADediting_1253589chr6_26525527_+SINEAluName=AluSc
ADediting_1253590chr6_26525544_+SINEAluName=AluSc
ADediting_1253591chr6_26525582_+SINEAluName=AluSc
ADediting_1253592chr6_26525583_+SINEAluName=AluSc
ADediting_1253593chr6_26526353_+SINEAluName=AluSc

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RNA A-to-I editing events in the alternative splicing sites for HCG11

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for HCG11

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

ADeditome IDChrPositoingSkipped exonENSGENSTs