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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for DRG1 |
 Gene summary |
| Gene information | Gene symbol | DRG1 | Gene ID | 4733 |
| Gene name | developmentally regulated GTP binding protein 1 | |
| Synonyms | NEDD3 | |
| Cytomap | 22q12.2 | |
| Type of gene | protein-coding | |
| Description | developmentally-regulated GTP-binding protein 1DRG-1NEDD-3TRAFAC GTPase DRG1neural precursor cell expressed developmentally down-regulated protein 3neural precursor cell expressed, developmentally down-regulated 3translation factor GTPase DRG1 | |
| Modification date | 20200313 | |
| UniProtAcc | Q9Y295, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
RNA A-to-I events for DRG1 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_984092(31401641, +), ADediting_984093(31402621, +), ADediting_984094(31402626, +), ADediting_984095(31402638, +), ADediting_984096(31402643, +), ADediting_984097(31402649, +), ADediting_984098(31402657, +), ADediting_984099(31402684, +), ADediting_984100(31402699, +), ADediting_984101(31403482, +), ADediting_984102(31403670, +), ADediting_984103(31403744, +), ADediting_984104(31403745, +), ADediting_984105(31404670, +), ADediting_984106(31404725, +), ADediting_984107(31404783, +), ADediting_984108(31404858, +), ADediting_984109(31404859, +), ADediting_984110(31404871, +), ADediting_984111(31404885, +), ADediting_984112(31404892, +), ADediting_984113(31404897, +), ADediting_984114(31405268, +), ADediting_984115(31405280, +), ADediting_984116(31407863, +), ADediting_984117(31408354, +), ADediting_984118(31408391, +), ADediting_984119(31409184, +), ADediting_984120(31409214, +), ADediting_984121(31409320, +), ADediting_984122(31409913, +), ADediting_984123(31413882, +), ADediting_984124(31417249, +), ADediting_984125(31418608, +), ADediting_984126(31418746, +), ADediting_984127(31418782, +), ADediting_984128(31419067, +), ADediting_984129(31421968, +), ADediting_984130(31422004, +), ADediting_984131(31422176, +), ADediting_984132(31430581, +), ADediting_984133(31431152, +), ADediting_984134(31431210, +), ADediting_984135(31431216, +), ADediting_984136(31431236, +), ADediting_984137(31431398, +), ADediting_984138(31431431, +), ADediting_984139(31431474, +), ADediting_984140(31431483, +), ADediting_984141(31431531, +), ADediting_984142(31431558, +), ADediting_984143(31431582, +), ADediting_984144(31431587, +), ADediting_984145(31434900, +), ADediting_984146(31434918, +), ADediting_984147(31434924, +), ADediting_984148(31434944, +), ADediting_984149(31434973, +), ADediting_984150(31434983, +), ADediting_984151(31434985, +), ADediting_984152(31434989, +), ADediting_984153(31435023, +), ADediting_984154(31435026, +), ADediting_984155(31435043, +), ADediting_984156(31435052, +), ADediting_984157(31435095, +), ADediting_984158(31435117, +), ADediting_984159(31435479, +), ADediting_984160(31435486, +), ADediting_984161(31435493, +), ADediting_984162(31435514, +), ADediting_984163(31435515, +), ADediting_984164(31435519, +), ADediting_984165(31435523, +), ADediting_984166(31435533, +), ADediting_984167(31435538, +), ADediting_984168(31435541, +), ADediting_984169(31435552, +), ADediting_984170(31435562, +), ADediting_984171(31435566, +), ADediting_984172(31435600, +), ADediting_984173(31435603, +), ADediting_984174(31435629, +), ADediting_984175(31435635, +), ADediting_984176(31435668, +), ADediting_984177(31435682, +), ADediting_984178(31435689, +), ADediting_984179(31435693, +), ADediting_984180(31435697, +), ADediting_984181(31435698, +), ADediting_984182(31500132, +), ADediting_984183(31500133, +), ADediting_984184(31500172, +), ADediting_984185(31500194, +), ADediting_984186(31500195, +), ADediting_984187(31500877, +), ADediting_984188(31500893, +), ADediting_984189(31501378, +), ADediting_984190(31505181, +), ADediting_984191(31511710, +), ADediting_984192(31512234, +), ADediting_984193(31512235, +), ADediting_984194(31512299, +), ADediting_984195(31512300, +), ADediting_984196(31512619, +), ADediting_984197(31512893, +), ADediting_984198(31513647, +), ADediting_984199(31513678, +), ADediting_984200(31513717, +), ADediting_984201(31513719, +), ADediting_984202(31513778, +), ADediting_984203(31513955, +), ADediting_984204(31514011, +), ADediting_984205(31514023, +), ADediting_984206(31514049, +), ADediting_984207(31514458, +), ADediting_984208(31514836, +), ADediting_984209(31514969, +), ADediting_984210(31515838, +), ADediting_984211(31515841, +), ADediting_984212(31515842, +), ADediting_984213(31515877, +), ADediting_984214(31515921, +), ADediting_984215(31516272, +), ADediting_984216(31516337, +), ADediting_984217(31516546, +), ADediting_984218(31516563, +), ADediting_984219(31516564, +), ADediting_984220(31516700, +), ADediting_984221(31517014, +), ADediting_984222(31520738, +), ADediting_984223(31520806, +), ADediting_984224(31520817, +), ADediting_984225(31520870, +), ADediting_984226(31520897, +), ADediting_984227(31520905, +), ADediting_984228(31520906, +), ADediting_984229(31522725, +), ADediting_984230(31522756, +), ADediting_984231(31526589, +), ADediting_984232(31526773, +), ADediting_984233(31526783, +), ADediting_984234(31527859, +), ADediting_984235(31527980, +), ADediting_984236(31528020, +), ADediting_984237(31530379, +), ADediting_984238(31530415, +), ADediting_1570396(31434908, +), ADediting_1570397(31434996, +), ADediting_1570398(31435064, +), ADediting_1642554(31411669, +), ADediting_1642555(31515903, +), |
Top |
RNA editing positional annotations for DRG1 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_984092 | chr22_31401641_+ | intronic |
| ADediting_984093 | chr22_31402621_+ | intronic |
| ADediting_984094 | chr22_31402626_+ | intronic |
| ADediting_984095 | chr22_31402638_+ | intronic |
| ADediting_984096 | chr22_31402643_+ | intronic |
| ADediting_984097 | chr22_31402649_+ | intronic |
| ADediting_984098 | chr22_31402657_+ | intronic |
| ADediting_984099 | chr22_31402684_+ | intronic |
| ADediting_984100 | chr22_31402699_+ | intronic |
| ADediting_984101 | chr22_31403482_+ | intronic |
| ADediting_984102 | chr22_31403670_+ | intronic |
| ADediting_984103 | chr22_31403744_+ | intronic |
| ADediting_984104 | chr22_31403745_+ | intronic |
| ADediting_984105 | chr22_31404670_+ | intronic |
| ADediting_984106 | chr22_31404725_+ | intronic |
| ADediting_984107 | chr22_31404783_+ | intronic |
| ADediting_984108 | chr22_31404858_+ | intronic |
| ADediting_984109 | chr22_31404859_+ | intronic |
| ADediting_984110 | chr22_31404871_+ | intronic |
| ADediting_984111 | chr22_31404885_+ | intronic |
| ADediting_984112 | chr22_31404892_+ | intronic |
| ADediting_984113 | chr22_31404897_+ | intronic |
| ADediting_984114 | chr22_31405268_+ | intronic |
| ADediting_984115 | chr22_31405280_+ | intronic |
| ADediting_984116 | chr22_31407863_+ | intronic |
| ADediting_984117 | chr22_31408354_+ | intronic |
| ADediting_984118 | chr22_31408391_+ | intronic |
| ADediting_984119 | chr22_31409184_+ | intronic |
| ADediting_984120 | chr22_31409214_+ | intronic |
| ADediting_984121 | chr22_31409320_+ | intronic |
| ADediting_984122 | chr22_31409913_+ | intronic |
| ADediting_984123 | chr22_31413882_+ | intronic |
| ADediting_984124 | chr22_31417249_+ | intronic |
| ADediting_984125 | chr22_31418608_+ | intronic |
| ADediting_984126 | chr22_31418746_+ | intronic |
| ADediting_984127 | chr22_31418782_+ | intronic |
| ADediting_984128 | chr22_31419067_+ | intronic |
| ADediting_984129 | chr22_31421968_+ | intronic |
| ADediting_984130 | chr22_31422004_+ | intronic |
| ADediting_984131 | chr22_31422176_+ | intronic |
| ADediting_984132 | chr22_31430581_+ | intronic |
| ADediting_984133 | chr22_31431152_+ | intronic |
| ADediting_984134 | chr22_31431210_+ | intronic |
| ADediting_984135 | chr22_31431216_+ | intronic |
| ADediting_984136 | chr22_31431236_+ | intronic |
| ADediting_984137 | chr22_31431398_+ | intronic |
| ADediting_984138 | chr22_31431431_+ | intronic |
| ADediting_984139 | chr22_31431474_+ | intronic |
| ADediting_984140 | chr22_31431483_+ | intronic |
| ADediting_984141 | chr22_31431531_+ | intronic |
| ADediting_984142 | chr22_31431558_+ | intronic |
| ADediting_984143 | chr22_31431582_+ | intronic |
| ADediting_984144 | chr22_31431587_+ | intronic |
| ADediting_984145 | chr22_31434900_+ | intronic |
| ADediting_984146 | chr22_31434918_+ | intronic |
| ADediting_984147 | chr22_31434924_+ | intronic |
| ADediting_984148 | chr22_31434944_+ | intronic |
| ADediting_984149 | chr22_31434973_+ | intronic |
| ADediting_984150 | chr22_31434983_+ | intronic |
| ADediting_984151 | chr22_31434985_+ | intronic |
| ADediting_984152 | chr22_31434989_+ | intronic |
| ADediting_984153 | chr22_31435023_+ | intronic |
| ADediting_984154 | chr22_31435026_+ | intronic |
| ADediting_984155 | chr22_31435043_+ | intronic |
| ADediting_984156 | chr22_31435052_+ | intronic |
| ADediting_984157 | chr22_31435095_+ | intronic |
| ADediting_984158 | chr22_31435117_+ | intronic |
| ADediting_984159 | chr22_31435479_+ | intronic |
| ADediting_984160 | chr22_31435486_+ | intronic |
| ADediting_984161 | chr22_31435493_+ | intronic |
| ADediting_984162 | chr22_31435514_+ | intronic |
| ADediting_984163 | chr22_31435515_+ | intronic |
| ADediting_984164 | chr22_31435519_+ | intronic |
| ADediting_984165 | chr22_31435523_+ | intronic |
| ADediting_984166 | chr22_31435533_+ | intronic |
| ADediting_984167 | chr22_31435538_+ | intronic |
| ADediting_984168 | chr22_31435541_+ | intronic |
| ADediting_984169 | chr22_31435552_+ | intronic |
| ADediting_984170 | chr22_31435562_+ | intronic |
| ADediting_984171 | chr22_31435566_+ | intronic |
| ADediting_984172 | chr22_31435600_+ | intronic |
| ADediting_984173 | chr22_31435603_+ | intronic |
| ADediting_984174 | chr22_31435629_+ | intronic |
| ADediting_984175 | chr22_31435635_+ | intronic |
| ADediting_984176 | chr22_31435668_+ | intronic |
| ADediting_984177 | chr22_31435682_+ | intronic |
| ADediting_984178 | chr22_31435689_+ | intronic |
| ADediting_984179 | chr22_31435693_+ | intronic |
| ADediting_984180 | chr22_31435697_+ | intronic |
| ADediting_984181 | chr22_31435698_+ | intronic |
| ADediting_984182 | chr22_31500132_+ | intronic |
| ADediting_984183 | chr22_31500133_+ | intronic |
| ADediting_984184 | chr22_31500172_+ | intronic |
| ADediting_984185 | chr22_31500194_+ | intronic |
| ADediting_984186 | chr22_31500195_+ | intronic |
| ADediting_984187 | chr22_31500877_+ | intronic |
| ADediting_984188 | chr22_31500893_+ | intronic |
| ADediting_984189 | chr22_31501378_+ | intronic |
| ADediting_984190 | chr22_31505181_+ | intronic |
| ADediting_984191 | chr22_31511710_+ | intronic |
| ADediting_984192 | chr22_31512234_+ | intronic |
| ADediting_984193 | chr22_31512235_+ | intronic |
| ADediting_984194 | chr22_31512299_+ | intronic |
| ADediting_984195 | chr22_31512300_+ | intronic |
| ADediting_984196 | chr22_31512619_+ | intronic |
| ADediting_984197 | chr22_31512893_+ | intronic |
| ADediting_984198 | chr22_31513647_+ | intronic |
| ADediting_984199 | chr22_31513678_+ | intronic |
| ADediting_984200 | chr22_31513717_+ | intronic |
| ADediting_984201 | chr22_31513719_+ | intronic |
| ADediting_984202 | chr22_31513778_+ | intronic |
| ADediting_984203 | chr22_31513955_+ | intronic |
| ADediting_984204 | chr22_31514011_+ | intronic |
| ADediting_984205 | chr22_31514023_+ | intronic |
| ADediting_984206 | chr22_31514049_+ | intronic |
| ADediting_984207 | chr22_31514458_+ | intronic |
| ADediting_984208 | chr22_31514836_+ | intronic |
| ADediting_984209 | chr22_31514969_+ | intronic |
| ADediting_984210 | chr22_31515838_+ | intronic |
| ADediting_984211 | chr22_31515841_+ | intronic |
| ADediting_984212 | chr22_31515842_+ | intronic |
| ADediting_984213 | chr22_31515877_+ | intronic |
| ADediting_984214 | chr22_31515921_+ | intronic |
| ADediting_984215 | chr22_31516272_+ | intronic |
| ADediting_984216 | chr22_31516337_+ | intronic |
| ADediting_984217 | chr22_31516546_+ | intronic |
| ADediting_984218 | chr22_31516563_+ | intronic |
| ADediting_984219 | chr22_31516564_+ | intronic |
| ADediting_984220 | chr22_31516700_+ | intronic |
| ADediting_984221 | chr22_31517014_+ | intronic |
| ADediting_984222 | chr22_31520738_+ | intronic |
| ADediting_984223 | chr22_31520806_+ | intronic |
| ADediting_984224 | chr22_31520817_+ | intronic |
| ADediting_984225 | chr22_31520870_+ | intronic |
| ADediting_984226 | chr22_31520897_+ | intronic |
| ADediting_984227 | chr22_31520905_+ | intronic |
| ADediting_984228 | chr22_31520906_+ | intronic |
| ADediting_984229 | chr22_31522725_+ | intronic |
| ADediting_984230 | chr22_31522756_+ | intronic |
| ADediting_984231 | chr22_31526589_+ | intronic |
| ADediting_984232 | chr22_31526773_+ | intronic |
| ADediting_984233 | chr22_31526783_+ | intronic |
| ADediting_984234 | chr22_31527859_+ | intronic |
| ADediting_984235 | chr22_31527980_+ | intronic |
| ADediting_984236 | chr22_31528020_+ | intronic |
| ADediting_984237 | chr22_31530379_+ | intronic |
| ADediting_984238 | chr22_31530415_+ | intronic |
| ADediting_1570396 | chr22_31434908_+ | intronic |
| ADediting_1570397 | chr22_31434996_+ | intronic |
| ADediting_1570398 | chr22_31435064_+ | intronic |
| ADediting_1642554 | chr22_31411669_+ | intronic |
| ADediting_1642555 | chr22_31515903_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_984092 | chr22_31401641_+ | SINE | Alu | Name=AluJr |
| ADediting_984093 | chr22_31402621_+ | SINE | Alu | Name=AluJb |
| ADediting_984094 | chr22_31402626_+ | SINE | Alu | Name=AluJb |
| ADediting_984095 | chr22_31402638_+ | SINE | Alu | Name=AluJb |
| ADediting_984096 | chr22_31402643_+ | SINE | Alu | Name=AluJb |
| ADediting_984097 | chr22_31402649_+ | SINE | Alu | Name=AluJb |
| ADediting_984098 | chr22_31402657_+ | SINE | Alu | Name=AluJb |
| ADediting_984099 | chr22_31402684_+ | SINE | Alu | Name=AluJb |
| ADediting_984100 | chr22_31402699_+ | SINE | Alu | Name=AluJb |
| ADediting_984101 | chr22_31403482_+ | SINE | Alu | Name=AluSp |
| ADediting_984102 | chr22_31403670_+ | SINE | Alu | Name=AluSx3 |
| ADediting_984103 | chr22_31403744_+ | SINE | Alu | Name=AluSx3 |
| ADediting_984104 | chr22_31403745_+ | SINE | Alu | Name=AluSx3 |
| ADediting_984105 | chr22_31404670_+ | SINE | Alu | Name=AluSz |
| ADediting_984106 | chr22_31404725_+ | SINE | Alu | Name=AluSz |
| ADediting_984107 | chr22_31404783_+ | SINE | Alu | Name=AluSz |
| ADediting_984108 | chr22_31404858_+ | SINE | Alu | Name=AluSz |
| ADediting_984109 | chr22_31404859_+ | SINE | Alu | Name=AluSz |
| ADediting_984110 | chr22_31404871_+ | SINE | Alu | Name=AluSz |
| ADediting_984111 | chr22_31404885_+ | SINE | Alu | Name=AluSz |
| ADediting_984112 | chr22_31404892_+ | SINE | Alu | Name=AluSz |
| ADediting_984113 | chr22_31404897_+ | SINE | Alu | Name=AluSz |
| ADediting_984114 | chr22_31405268_+ | SINE | Alu | Name=AluSx4 |
| ADediting_984115 | chr22_31405280_+ | SINE | Alu | Name=AluSx4 |
| ADediting_984116 | chr22_31407863_+ | SINE | Alu | Name=AluSx1 |
| ADediting_984117 | chr22_31408354_+ | SINE | Alu | Name=AluSx1 |
| ADediting_984118 | chr22_31408391_+ | SINE | Alu | Name=AluSx1 |
| ADediting_984119 | chr22_31409184_+ | SINE | Alu | Name=AluSz |
| ADediting_984120 | chr22_31409214_+ | SINE | Alu | Name=AluSz |
| ADediting_984121 | chr22_31409320_+ | SINE | Alu | Name=AluSz |
| ADediting_984122 | chr22_31409913_+ | SINE | Alu | Name=AluSx3 |
| ADediting_984123 | chr22_31413882_+ | SINE | Alu | Name=AluSx1 |
| ADediting_984124 | chr22_31417249_+ | SINE | Alu | Name=AluSc |
| ADediting_984125 | chr22_31418608_+ | SINE | Alu | Name=AluSx1 |
| ADediting_984126 | chr22_31418746_+ | SINE | Alu | Name=AluSc8 |
| ADediting_984127 | chr22_31418782_+ | SINE | Alu | Name=AluSc8 |
| ADediting_984128 | chr22_31419067_+ | SINE | Alu | Name=AluSx1 |
| ADediting_984129 | chr22_31421968_+ | SINE | Alu | Name=AluSc |
| ADediting_984130 | chr22_31422004_+ | SINE | Alu | Name=AluSc |
| ADediting_984131 | chr22_31422176_+ | SINE | Alu | Name=AluSq |
| ADediting_984132 | chr22_31430581_+ | SINE | Alu | Name=AluY |
| ADediting_984133 | chr22_31431152_+ | SINE | Alu | Name=AluY |
| ADediting_984134 | chr22_31431210_+ | SINE | Alu | Name=AluY |
| ADediting_984135 | chr22_31431216_+ | SINE | Alu | Name=AluY |
| ADediting_984136 | chr22_31431236_+ | SINE | Alu | Name=AluY |
| ADediting_984137 | chr22_31431398_+ | SINE | Alu | Name=AluJo |
| ADediting_984138 | chr22_31431431_+ | SINE | Alu | Name=AluJo |
| ADediting_984139 | chr22_31431474_+ | SINE | Alu | Name=AluJo |
| ADediting_984140 | chr22_31431483_+ | SINE | Alu | Name=AluJo |
| ADediting_984141 | chr22_31431531_+ | SINE | Alu | Name=AluJo |
| ADediting_984142 | chr22_31431558_+ | SINE | Alu | Name=AluJo |
| ADediting_984143 | chr22_31431582_+ | SINE | Alu | Name=AluJo |
| ADediting_984144 | chr22_31431587_+ | SINE | Alu | Name=AluJo |
| ADediting_984145 | chr22_31434900_+ | SINE | Alu | Name=AluSp |
| ADediting_984146 | chr22_31434918_+ | SINE | Alu | Name=AluSp |
| ADediting_984147 | chr22_31434924_+ | SINE | Alu | Name=AluSp |
| ADediting_984148 | chr22_31434944_+ | SINE | Alu | Name=AluSp |
| ADediting_984149 | chr22_31434973_+ | SINE | Alu | Name=AluSp |
| ADediting_984150 | chr22_31434983_+ | SINE | Alu | Name=AluSp |
| ADediting_984151 | chr22_31434985_+ | SINE | Alu | Name=AluSp |
| ADediting_984152 | chr22_31434989_+ | SINE | Alu | Name=AluSp |
| ADediting_984153 | chr22_31435023_+ | SINE | Alu | Name=AluSp |
| ADediting_984154 | chr22_31435026_+ | SINE | Alu | Name=AluSp |
| ADediting_984155 | chr22_31435043_+ | SINE | Alu | Name=AluSp |
| ADediting_984156 | chr22_31435052_+ | SINE | Alu | Name=AluSp |
| ADediting_984157 | chr22_31435095_+ | SINE | Alu | Name=AluSp |
| ADediting_984158 | chr22_31435117_+ | SINE | Alu | Name=AluSp |
| ADediting_984159 | chr22_31435479_+ | SINE | Alu | Name=AluJo |
| ADediting_984160 | chr22_31435486_+ | SINE | Alu | Name=AluJo |
| ADediting_984161 | chr22_31435493_+ | SINE | Alu | Name=AluJo |
| ADediting_984162 | chr22_31435514_+ | SINE | Alu | Name=AluJo |
| ADediting_984163 | chr22_31435515_+ | SINE | Alu | Name=AluJo |
| ADediting_984164 | chr22_31435519_+ | SINE | Alu | Name=AluJo |
| ADediting_984165 | chr22_31435523_+ | SINE | Alu | Name=AluJo |
| ADediting_984166 | chr22_31435533_+ | SINE | Alu | Name=AluJo |
| ADediting_984167 | chr22_31435538_+ | SINE | Alu | Name=AluJo |
| ADediting_984168 | chr22_31435541_+ | SINE | Alu | Name=AluJo |
| ADediting_984169 | chr22_31435552_+ | SINE | Alu | Name=AluJo |
| ADediting_984170 | chr22_31435562_+ | SINE | Alu | Name=AluJo |
| ADediting_984171 | chr22_31435566_+ | SINE | Alu | Name=AluJo |
| ADediting_984172 | chr22_31435600_+ | SINE | Alu | Name=AluJo |
| ADediting_984173 | chr22_31435603_+ | SINE | Alu | Name=AluJo |
| ADediting_984174 | chr22_31435629_+ | SINE | Alu | Name=AluJo |
| ADediting_984175 | chr22_31435635_+ | SINE | Alu | Name=AluJo |
| ADediting_984176 | chr22_31435668_+ | SINE | Alu | Name=AluJo |
| ADediting_984177 | chr22_31435682_+ | SINE | Alu | Name=AluJo |
| ADediting_984178 | chr22_31435689_+ | SINE | Alu | Name=AluJo |
| ADediting_984179 | chr22_31435693_+ | SINE | Alu | Name=AluJo |
| ADediting_984180 | chr22_31435697_+ | SINE | Alu | Name=AluJo |
| ADediting_984181 | chr22_31435698_+ | SINE | Alu | Name=AluJo |
| ADediting_984182 | chr22_31500132_+ | SINE | Alu | Name=AluSx1 |
| ADediting_984183 | chr22_31500133_+ | SINE | Alu | Name=AluSx1 |
| ADediting_984184 | chr22_31500172_+ | SINE | Alu | Name=AluSx1 |
| ADediting_984185 | chr22_31500194_+ | SINE | Alu | Name=AluSx1 |
| ADediting_984186 | chr22_31500195_+ | SINE | Alu | Name=AluSx1 |
| ADediting_984187 | chr22_31500877_+ | SINE | Alu | Name=AluSg4 |
| ADediting_984188 | chr22_31500893_+ | SINE | Alu | Name=AluSg4 |
| ADediting_984189 | chr22_31501378_+ | SINE | Alu | Name=AluY |
| ADediting_984190 | chr22_31505181_+ | SINE | Alu | Name=AluSz |
| ADediting_984191 | chr22_31511710_+ | SINE | Alu | Name=AluSz6 |
| ADediting_984192 | chr22_31512234_+ | SINE | Alu | Name=AluSp |
| ADediting_984193 | chr22_31512235_+ | SINE | Alu | Name=AluSp |
| ADediting_984194 | chr22_31512299_+ | SINE | Alu | Name=AluSp |
| ADediting_984195 | chr22_31512300_+ | SINE | Alu | Name=AluSp |
| ADediting_984196 | chr22_31512619_+ | SINE | Alu | Name=AluSx1 |
| ADediting_984197 | chr22_31512893_+ | SINE | Alu | Name=AluY |
| ADediting_984198 | chr22_31513647_+ | SINE | Alu | Name=AluSx3 |
| ADediting_984199 | chr22_31513678_+ | SINE | Alu | Name=AluSx3 |
| ADediting_984200 | chr22_31513717_+ | SINE | Alu | Name=AluSx3 |
| ADediting_984201 | chr22_31513719_+ | SINE | Alu | Name=AluSx3 |
| ADediting_984202 | chr22_31513778_+ | SINE | Alu | Name=AluSx3 |
| ADediting_984203 | chr22_31513955_+ | SINE | Alu | Name=AluSx |
| ADediting_984204 | chr22_31514011_+ | SINE | Alu | Name=AluSx |
| ADediting_984205 | chr22_31514023_+ | SINE | Alu | Name=AluSx |
| ADediting_984206 | chr22_31514049_+ | SINE | Alu | Name=AluSx |
| ADediting_984207 | chr22_31514458_+ | SINE | Alu | Name=AluY |
| ADediting_984208 | chr22_31514836_+ | SINE | Alu | Name=AluSc |
| ADediting_984209 | chr22_31514969_+ | SINE | Alu | Name=AluSc |
| ADediting_984210 | chr22_31515838_+ | SINE | Alu | Name=AluSg |
| ADediting_984211 | chr22_31515841_+ | SINE | Alu | Name=AluSg |
| ADediting_984212 | chr22_31515842_+ | SINE | Alu | Name=AluSg |
| ADediting_984213 | chr22_31515877_+ | SINE | Alu | Name=AluSg |
| ADediting_984214 | chr22_31515921_+ | SINE | Alu | Name=AluSg |
| ADediting_984215 | chr22_31516272_+ | SINE | Alu | Name=AluSz |
| ADediting_984216 | chr22_31516337_+ | SINE | Alu | Name=AluSz |
| ADediting_984217 | chr22_31516546_+ | SINE | Alu | Name=AluSz |
| ADediting_984218 | chr22_31516563_+ | SINE | Alu | Name=AluSz |
| ADediting_984219 | chr22_31516564_+ | SINE | Alu | Name=AluSz |
| ADediting_984220 | chr22_31516700_+ | SINE | Alu | Name=AluSp |
| ADediting_984221 | chr22_31517014_+ | SINE | Alu | Name=AluSz |
| ADediting_984222 | chr22_31520738_+ | SINE | Alu | Name=AluJb |
| ADediting_984223 | chr22_31520806_+ | SINE | Alu | Name=AluJb |
| ADediting_984224 | chr22_31520817_+ | SINE | Alu | Name=AluJb |
| ADediting_984225 | chr22_31520870_+ | SINE | Alu | Name=AluJb |
| ADediting_984226 | chr22_31520897_+ | SINE | Alu | Name=AluJb |
| ADediting_984227 | chr22_31520905_+ | SINE | Alu | Name=AluJb |
| ADediting_984228 | chr22_31520906_+ | SINE | Alu | Name=AluJb |
| ADediting_984229 | chr22_31522725_+ | SINE | Alu | Name=AluSc |
| ADediting_984230 | chr22_31522756_+ | SINE | Alu | Name=AluSc |
| ADediting_984231 | chr22_31526589_+ | SINE | Alu | Name=AluSx |
| ADediting_984232 | chr22_31526773_+ | SINE | Alu | Name=AluSx |
| ADediting_984233 | chr22_31526783_+ | SINE | Alu | Name=AluSx |
| ADediting_984234 | chr22_31527859_+ | SINE | Alu | Name=AluSx1 |
| ADediting_984235 | chr22_31527980_+ | SINE | Alu | Name=AluSx1 |
| ADediting_984236 | chr22_31528020_+ | SINE | Alu | Name=AluSx1 |
| ADediting_984237 | chr22_31530379_+ | SINE | Alu | Name=AluY |
| ADediting_984238 | chr22_31530415_+ | SINE | Alu | Name=AluY |
| ADediting_1570396 | chr22_31434908_+ | SINE | Alu | Name=AluSp |
| ADediting_1570397 | chr22_31434996_+ | SINE | Alu | Name=AluSp |
| ADediting_1570398 | chr22_31435064_+ | SINE | Alu | Name=AluSp |
| ADediting_1642554 | chr22_31411669_+ | SINE | Alu | Name=AluSz |
| ADediting_1642555 | chr22_31515903_+ | SINE | Alu | Name=AluSg |
Top |
RNA A-to-I editing events in the alternative splicing sites for DRG1 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for DRG1 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for DRG1 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for DRG1 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1535953 | chr14_101045971_+ | ENSG00000185721.13 | ENST00000331457.9 | DRG1-201 | hsa-miR-381-3p | chr22 | 31434135 | 31434141 | 7mer-m8 | 31434121 | 31434142 | 148 | -15.02 |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000185721.13 | ENST00000331457.9 | DRG1-201 | hsa-miR-381-3p | chr22 | 31434135 | 31434141 | 7mer-m8 | 31434121 | 31434142 | 148 | -15.02 |
| Differentially expressed gene-miRNA network |
Top |
The effects of the RNA editing to the stability of the RNA structures for DRG1 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
Top |
Relation with ADAR for DRG1 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_1570397 | chr22_31434996_+ | 0.00184679373850471 | 0.252228997333686 | 2.27633683831271e-05 | 0.338429487150919 | 0.586635236655317 | 0.0447465043698586 |
| CER | ADediting_984147 | chr22_31434924_+ | 2.19544130347026e-14 | 0.571561200327871 | 4.09488921922477e-15 | 0.584463964911483 | 0.000581385220542754 | 0.277665985480865 |
| TCX | ADediting_984147 | chr22_31434924_+ | 4.94308131815465e-08 | 0.427298908313016 | 0.00428871089472402 | 0.231951404293929 | 0.0161648347308071 | 0.196111184166241 |
| CER | ADediting_984149 | chr22_31434973_+ | 1.74337001382216e-09 | 0.466724351095926 | 4.94744894134259e-12 | 0.525664708926054 | 0.000147340475057186 | 0.305034828127621 |
| CER | ADediting_984150 | chr22_31434983_+ | 1.24588798608588e-11 | 0.51709789429912 | 2.8461980919419e-12 | 0.530680733786453 | 4.96991098534592e-05 | 0.32493931835723 |
| TCX | ADediting_984150 | chr22_31434983_+ | 1.70130187510684e-09 | 0.466994623538001 | 0.000795302350010065 | 0.271010636188346 | 0.00198105912649778 | 0.25060097428607 |
| CER | ADediting_984151 | chr22_31434985_+ | 5.71152981393161e-06 | 0.360885659285519 | 1.20101650461454e-06 | 0.384328283086717 | 0.0177351917383899 | 0.193386094215997 |
| TCX | ADediting_984151 | chr22_31434985_+ | 8.80247281580764e-06 | 0.354042870868849 | 4.29908092440779e-08 | 0.429048524182571 | 0.207135940396782 | -0.103588648288521 |
| CER | ADediting_984152 | chr22_31434989_+ | 0.00976899939991168 | 0.210368066938551 | 5.04209516407106e-06 | 0.362828896899693 | 0.13599401325603 | 0.122295178713775 |
| CER | ADediting_984153 | chr22_31435023_+ | 0.00409046286478324 | 0.233135405037915 | 8.88738010630585e-05 | 0.314468485807389 | 0.864230774007072 | 0.0140784447771389 |
| CER | ADediting_984155 | chr22_31435043_+ | 7.71945827501485e-05 | 0.317042244226006 | 1.057706053983e-06 | 0.386160513612722 | 0.0760746767732562 | 0.145286673146782 |
| CER | ADediting_984157 | chr22_31435095_+ | 0.000210439160213985 | 0.298186124562768 | 0.000123460740310942 | 0.308370715454698 | 0.0411383258276875 | 0.16696390950629 |
| CER | ADediting_984159 | chr22_31435479_+ | 1.30631356839656e-06 | 0.383110331052551 | 4.67084495431569e-08 | 0.428010149910433 | 0.000107631564733756 | 0.310932157443191 |
| TCX | ADediting_984159 | chr22_31435479_+ | 2.61633586878367e-10 | 0.487040219559132 | 5.51838838732425e-05 | 0.323081648710449 | 0.002156568529234 | 0.248617777015839 |
| CER | ADediting_984162 | chr22_31435514_+ | 0.000394387263959254 | 0.28568648147869 | 8.88426776615516e-06 | 0.353894806028391 | 0.195250071494986 | 0.106342378445661 |
| CER | ADediting_984164 | chr22_31435519_+ | 0.000505542313593523 | 0.280582510104981 | 1.05475358959922e-05 | 0.351134084958099 | 0.00794579813309118 | 0.215970702583252 |
| CER | ADediting_984167 | chr22_31435538_+ | 0.00308141438395563 | 0.240105402828221 | 1.17790604225279e-06 | 0.384609173266964 | 0.00510561509937233 | 0.227539375140015 |
| CER | ADediting_984169 | chr22_31435552_+ | 3.12675677947937e-07 | 0.403194317625647 | 4.36188357271607e-11 | 0.505079061635171 | 0.00839046142974751 | 0.214506775106295 |
| CER | ADediting_984171 | chr22_31435566_+ | 3.59767410725746e-12 | 0.52856508958901 | 5.53310643021771e-14 | 0.564210401378007 | 0.000145945580934056 | 0.305215300987353 |
| TCX | ADediting_984171 | chr22_31435566_+ | 9.82572322960695e-09 | 0.446967905924424 | 0.00428090401184583 | 0.231997090933517 | 0.00167941914374145 | 0.254416432897077 |
| CER | ADediting_984173 | chr22_31435603_+ | 8.94334835176171e-05 | 0.314353256206657 | 0.0010930996512719 | 0.264078609608411 | 0.0302139554025855 | 0.177037955550204 |
| TCX | ADediting_984173 | chr22_31435603_+ | 4.41620691154457e-05 | 0.327021055893152 | 0.0417078952575282 | 0.166503597556254 | 0.0132079813886947 | 0.201937253937608 |
| CER | ADediting_984174 | chr22_31435629_+ | 3.51568735726819e-12 | 0.528773893985202 | 3.00995340230863e-16 | 0.603451721216551 | 0.00588323433761986 | 0.223891880812169 |
| TCX | ADediting_984174 | chr22_31435629_+ | 3.62872536277839e-08 | 0.43116008956778 | 0.000220837101426383 | 0.29724632811682 | 0.00698919652462735 | 0.219383974621461 |
| CER | ADediting_984176 | chr22_31435668_+ | 9.14418822663166e-06 | 0.353432711441737 | 5.24137081731382e-06 | 0.362226057013658 | 0.0034031897651531 | 0.237683763040551 |
| TCX | ADediting_984176 | chr22_31435668_+ | 0.000177697496365818 | 0.301456499169349 | 0.0215520321960065 | 0.187545607103178 | 0.0937167124078985 | 0.137353387659573 |
| CER | ADediting_984178 | chr22_31435689_+ | 2.96106459901814e-11 | 0.508844767643316 | 1.5240784215627e-14 | 0.574414220060669 | 0.00173046910574162 | 0.25372897908814 |
| TCX | ADediting_984178 | chr22_31435689_+ | 9.08625757949768e-09 | 0.44788950223012 | 1.48890600010925e-05 | 0.345508755134207 | 0.0130315384462219 | 0.202319853858902 |
| CER | ADediting_984181 | chr22_31435698_+ | 0.02311034639575 | 0.185415599322653 | 0.000153369987643965 | 0.304272600170049 | 0.763541419011379 | 0.0247663706780389 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 2.80809452635547e-51 | 0.72240041512208 | 2.54282495842729e-61 | 0.767053908939566 | 0.063780115678131 | 0.105416198729983 |
| AC | 1.85447537078382e-81 | 0.878335681141735 | 2.41324861054217e-51 | 0.775011708218205 | 1.00883819564595e-15 | 0.478681372927699 |
| PCC | 4.6957989159179e-28 | 0.687402568018271 | 4.09374410989971e-33 | 0.730348567568197 | 0.127282728937973 | 0.110725551250116 |
| CER | 8.91161710296421e-08 | 0.41980042685361 | 8.31342965943565e-05 | 0.315690984740432 | 0.752847103073927 | -0.0259229895499209 |
| TCX | 3.7236149198827e-21 | 0.6733623467115 | 2.32019142610872e-21 | 0.675923563162817 | 0.39072727980771 | -0.0705828357300899 |
| FP | 1.45176795648269e-17 | 0.582599264369735 | 4.94600293192882e-16 | 0.559202500013231 | 0.349328841472978 | -0.0705576892645905 |
| IFG | 0.00423853756668053 | 0.551840348714019 | 0.090129644836677 | 0.346094981661002 | 0.128800567326414 | -0.312101970134245 |
| PG | 1.11579840020638e-55 | 0.860094548625162 | 3.68442420629119e-26 | 0.675732572700744 | 0.79311162263458 | -0.0193594332341429 |
| STG | 3.58628064929991e-21 | 0.815497377785112 | 3.8354510958579e-13 | 0.690099122699444 | 0.495070137285728 | -0.0754659474389482 |
Top |
Relation with AD stages for DRG1 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_984149 | chr22_31434973_+ | 0.000550434837900432 | 0.327064283651648 |
| CER | ADediting_984150 | chr22_31434983_+ | 0.00021365081786143 | 0.349043369868364 |
| CER | ADediting_984162 | chr22_31435514_+ | 0.00029709944031667 | 0.341568094394789 |
| CER | ADediting_984167 | chr22_31435538_+ | 3.33660053472896e-05 | 0.388011943022058 |
| CER | ADediting_984169 | chr22_31435552_+ | 0.000178209140627563 | 0.353077705727235 |
| CER | ADediting_984171 | chr22_31435566_+ | 0.00041239993634265 | 0.333943371312036 |
| CER | ADediting_984173 | chr22_31435603_+ | 0.00157572572908678 | 0.300540434760026 |
| CER | ADediting_984174 | chr22_31435629_+ | 3.74828600383879e-06 | 0.428365862936993 |
| CER | ADediting_984178 | chr22_31435689_+ | 0.00114399025092456 | 0.308875310570779 |
| TCX | ADediting_984150 | chr22_31434983_+ | 0.000288139999294245 | 0.3453573797787 |
| TCX | ADediting_984171 | chr22_31435566_+ | 0.000103666764518318 | 0.368076628796901 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
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RelatedDrugs for DRG1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for DRG1 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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