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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for NCBP1

check button Gene summary
Gene informationGene symbol

NCBP1

Gene ID

4686

Gene namenuclear cap binding protein subunit 1
SynonymsCBP80|NCBP|Sto1
Cytomap

9q22.33

Type of geneprotein-coding
Descriptionnuclear cap-binding protein subunit 180 kDa nuclear cap-binding proteinNCBP 80 kDa subunitnuclear cap binding protein subunit 1, 80kDa
Modification date20200313
UniProtAcc

Q09161,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
NCBP1

GO:0000184

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

11551508|17873884

NCBP1

GO:0006370

7-methylguanosine mRNA capping

12434151

NCBP1

GO:0006446

regulation of translational initiation

11551508


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RNA A-to-I events for NCBP1

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_1483706(97652298, +), ADediting_1483707(97652360, +), ADediting_1483708(97652363, +), ADediting_1483709(97652432, +), ADediting_1483710(97652434, +), ADediting_1483711(97652439, +), ADediting_1483712(97652440, +), ADediting_1483713(97652484, +), ADediting_1483714(97652488, +), ADediting_1483715(97652496, +), ADediting_1483716(97652535, +), ADediting_1483717(97652540, +), ADediting_1483718(97656310, +), ADediting_1483719(97656326, +), ADediting_1483720(97656327, +), ADediting_1483721(97656332, +), ADediting_1483722(97656335, +), ADediting_1483723(97656348, +), ADediting_1483724(97656349, +), ADediting_1483725(97656350, +), ADediting_1483726(97656380, +), ADediting_1483727(97656394, +), ADediting_1483728(97656395, +), ADediting_1483729(97656427, +), ADediting_1483730(97656429, +), ADediting_1483731(97656449, +), ADediting_1483732(97656450, +), ADediting_1483733(97656456, +), ADediting_1483734(97656458, +), ADediting_1483735(97656459, +), ADediting_1483736(97656500, +), ADediting_1483737(97656522, +), ADediting_1483738(97657085, +), ADediting_1483739(97657096, +), ADediting_1483740(97657106, +), ADediting_1483741(97657108, +), ADediting_1483742(97657148, +), ADediting_1483743(97657151, +), ADediting_1483744(97657173, +), ADediting_1483745(97657227, +), ADediting_1483746(97657228, +), ADediting_1483747(97657235, +), ADediting_1483748(97657240, +), ADediting_1483749(97657246, +), ADediting_1483750(97663565, +), ADediting_1483751(97663584, +), ADediting_1483752(97663585, +), ADediting_1483753(97663602, +), ADediting_1483754(97663624, +), ADediting_1483755(97663642, +), ADediting_1483756(97663685, +), ADediting_1483757(97663719, +), ADediting_1483758(97663760, +), ADediting_1483759(97663923, +), ADediting_1483760(97663924, +), ADediting_1483761(97663929, +), ADediting_1483762(97663959, +), ADediting_1483763(97663964, +), ADediting_1483764(97663965, +), ADediting_1483765(97663969, +), ADediting_1483766(97663988, +), ADediting_1483767(97663997, +), ADediting_1483768(97664019, +), ADediting_1483769(97664020, +), ADediting_1483770(97664023, +), ADediting_1483771(97664028, +), ADediting_1483772(97664029, +), ADediting_1483773(97664040, +), ADediting_1483774(97664052, +), ADediting_1483775(97664058, +), ADediting_1483776(97664059, +), ADediting_1483777(97664072, +), ADediting_1483778(97664085, +), ADediting_1483779(97664099, +), ADediting_1483780(97664100, +), ADediting_1483781(97664104, +), ADediting_1483782(97664154, +), ADediting_1483783(97672874, +), ADediting_1483784(97672945, +), ADediting_1483785(97672962, +), ADediting_1483786(97672965, +), ADediting_1483787(97672981, +), ADediting_1483788(97672985, +), ADediting_1483789(97673007, +), ADediting_1483790(97673040, +), ADediting_1483791(97673048, +), ADediting_1483792(97673049, +), ADediting_1483793(97673077, +), ADediting_1483794(97673078, +), ADediting_1594489(97656405, +), ADediting_1594490(97656436, +), ADediting_1594491(97657012, +), ADediting_1594492(97657024, +), ADediting_1594493(97663978, +), ADediting_1594494(97663983, +), ADediting_1594495(97664027, +), ADediting_1594496(97664088, +), ADediting_1594497(97664091, +), ADediting_1674364(97642827, +), ADediting_1674365(97652062, +), ADediting_1674366(97652107, +), ADediting_1674367(97652133, +), ADediting_1674368(97652187, +), ADediting_1674369(97652397, +), ADediting_1674370(97652441, +), ADediting_1674371(97652553, +), ADediting_1674372(97663659, +), ADediting_1674373(97663668, +), ADediting_1674374(97664003, +), ADediting_1674375(97664026, +),

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RNA editing positional annotations for NCBP1 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_1483706chr9_97652298_+intronic
ADediting_1483707chr9_97652360_+intronic
ADediting_1483708chr9_97652363_+intronic
ADediting_1483709chr9_97652432_+intronic
ADediting_1483710chr9_97652434_+intronic
ADediting_1483711chr9_97652439_+intronic
ADediting_1483712chr9_97652440_+intronic
ADediting_1483713chr9_97652484_+intronic
ADediting_1483714chr9_97652488_+intronic
ADediting_1483715chr9_97652496_+intronic
ADediting_1483716chr9_97652535_+intronic
ADediting_1483717chr9_97652540_+intronic
ADediting_1483718chr9_97656310_+intronic
ADediting_1483719chr9_97656326_+intronic
ADediting_1483720chr9_97656327_+intronic
ADediting_1483721chr9_97656332_+intronic
ADediting_1483722chr9_97656335_+intronic
ADediting_1483723chr9_97656348_+intronic
ADediting_1483724chr9_97656349_+intronic
ADediting_1483725chr9_97656350_+intronic
ADediting_1483726chr9_97656380_+intronic
ADediting_1483727chr9_97656394_+intronic
ADediting_1483728chr9_97656395_+intronic
ADediting_1483729chr9_97656427_+intronic
ADediting_1483730chr9_97656429_+intronic
ADediting_1483731chr9_97656449_+intronic
ADediting_1483732chr9_97656450_+intronic
ADediting_1483733chr9_97656456_+intronic
ADediting_1483734chr9_97656458_+intronic
ADediting_1483735chr9_97656459_+intronic
ADediting_1483736chr9_97656500_+intronic
ADediting_1483737chr9_97656522_+intronic
ADediting_1483738chr9_97657085_+intronic
ADediting_1483739chr9_97657096_+intronic
ADediting_1483740chr9_97657106_+intronic
ADediting_1483741chr9_97657108_+intronic
ADediting_1483742chr9_97657148_+intronic
ADediting_1483743chr9_97657151_+intronic
ADediting_1483744chr9_97657173_+intronic
ADediting_1483745chr9_97657227_+intronic
ADediting_1483746chr9_97657228_+intronic
ADediting_1483747chr9_97657235_+intronic
ADediting_1483748chr9_97657240_+intronic
ADediting_1483749chr9_97657246_+intronic
ADediting_1483750chr9_97663565_+intronic
ADediting_1483751chr9_97663584_+intronic
ADediting_1483752chr9_97663585_+intronic
ADediting_1483753chr9_97663602_+intronic
ADediting_1483754chr9_97663624_+intronic
ADediting_1483755chr9_97663642_+intronic
ADediting_1483756chr9_97663685_+intronic
ADediting_1483757chr9_97663719_+intronic
ADediting_1483758chr9_97663760_+intronic
ADediting_1483759chr9_97663923_+intronic
ADediting_1483760chr9_97663924_+intronic
ADediting_1483761chr9_97663929_+intronic
ADediting_1483762chr9_97663959_+intronic
ADediting_1483763chr9_97663964_+intronic
ADediting_1483764chr9_97663965_+intronic
ADediting_1483765chr9_97663969_+intronic
ADediting_1483766chr9_97663988_+intronic
ADediting_1483767chr9_97663997_+intronic
ADediting_1483768chr9_97664019_+intronic
ADediting_1483769chr9_97664020_+intronic
ADediting_1483770chr9_97664023_+intronic
ADediting_1483771chr9_97664028_+intronic
ADediting_1483772chr9_97664029_+intronic
ADediting_1483773chr9_97664040_+intronic
ADediting_1483774chr9_97664052_+intronic
ADediting_1483775chr9_97664058_+intronic
ADediting_1483776chr9_97664059_+intronic
ADediting_1483777chr9_97664072_+intronic
ADediting_1483778chr9_97664085_+intronic
ADediting_1483779chr9_97664099_+intronic
ADediting_1483780chr9_97664100_+intronic
ADediting_1483781chr9_97664104_+intronic
ADediting_1483782chr9_97664154_+intronic
ADediting_1483783chr9_97672874_+UTR3
ADediting_1483784chr9_97672945_+UTR3
ADediting_1483785chr9_97672962_+UTR3
ADediting_1483786chr9_97672965_+UTR3
ADediting_1483787chr9_97672981_+UTR3
ADediting_1483788chr9_97672985_+UTR3
ADediting_1483789chr9_97673007_+UTR3
ADediting_1483790chr9_97673040_+UTR3
ADediting_1483791chr9_97673048_+UTR3
ADediting_1483792chr9_97673049_+UTR3
ADediting_1483793chr9_97673077_+UTR3
ADediting_1483794chr9_97673078_+UTR3
ADediting_1594489chr9_97656405_+intronic
ADediting_1594490chr9_97656436_+intronic
ADediting_1594491chr9_97657012_+intronic
ADediting_1594492chr9_97657024_+intronic
ADediting_1594493chr9_97663978_+intronic
ADediting_1594494chr9_97663983_+intronic
ADediting_1594495chr9_97664027_+intronic
ADediting_1594496chr9_97664088_+intronic
ADediting_1594497chr9_97664091_+intronic
ADediting_1674364chr9_97642827_+intronic
ADediting_1674365chr9_97652062_+intronic
ADediting_1674366chr9_97652107_+intronic
ADediting_1674367chr9_97652133_+intronic
ADediting_1674368chr9_97652187_+intronic
ADediting_1674369chr9_97652397_+intronic
ADediting_1674370chr9_97652441_+intronic
ADediting_1674371chr9_97652553_+intronic
ADediting_1674372chr9_97663659_+intronic
ADediting_1674373chr9_97663668_+intronic
ADediting_1674374chr9_97664003_+intronic
ADediting_1674375chr9_97664026_+intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_1483706chr9_97652298_+SINEAluName=AluSx4
ADediting_1483707chr9_97652360_+SINEAluName=AluJb
ADediting_1483708chr9_97652363_+SINEAluName=AluJb
ADediting_1483709chr9_97652432_+SINEAluName=AluJb
ADediting_1483710chr9_97652434_+SINEAluName=AluJb
ADediting_1483711chr9_97652439_+SINEAluName=AluJb
ADediting_1483712chr9_97652440_+SINEAluName=AluJb
ADediting_1483713chr9_97652484_+SINEAluName=AluJb
ADediting_1483714chr9_97652488_+SINEAluName=AluJb
ADediting_1483715chr9_97652496_+SINEAluName=AluJb
ADediting_1483716chr9_97652535_+SINEAluName=AluJb
ADediting_1483717chr9_97652540_+SINEAluName=AluJb
ADediting_1483718chr9_97656310_+SINEAluName=AluSx1
ADediting_1483719chr9_97656326_+SINEAluName=AluSx1
ADediting_1483720chr9_97656327_+SINEAluName=AluSx1
ADediting_1483721chr9_97656332_+SINEAluName=AluSx1
ADediting_1483722chr9_97656335_+SINEAluName=AluSx1
ADediting_1483723chr9_97656348_+SINEAluName=AluSx1
ADediting_1483724chr9_97656349_+SINEAluName=AluSx1
ADediting_1483725chr9_97656350_+SINEAluName=AluSx1
ADediting_1483726chr9_97656380_+SINEAluName=AluSx1
ADediting_1483727chr9_97656394_+SINEAluName=AluSx1
ADediting_1483728chr9_97656395_+SINEAluName=AluSx1
ADediting_1483729chr9_97656427_+SINEAluName=AluSx1
ADediting_1483730chr9_97656429_+SINEAluName=AluSx1
ADediting_1483731chr9_97656449_+SINEAluName=AluSx1
ADediting_1483732chr9_97656450_+SINEAluName=AluSx1
ADediting_1483733chr9_97656456_+SINEAluName=AluSx1
ADediting_1483734chr9_97656458_+SINEAluName=AluSx1
ADediting_1483735chr9_97656459_+SINEAluName=AluSx1
ADediting_1483736chr9_97656500_+SINEAluName=AluSx1
ADediting_1483737chr9_97656522_+SINEAluName=AluSx1
ADediting_1483738chr9_97657085_+SINEAluName=AluY
ADediting_1483739chr9_97657096_+SINEAluName=AluY
ADediting_1483740chr9_97657106_+SINEAluName=AluY
ADediting_1483741chr9_97657108_+SINEAluName=AluY
ADediting_1483742chr9_97657148_+SINEAluName=AluY
ADediting_1483743chr9_97657151_+SINEAluName=AluY
ADediting_1483744chr9_97657173_+SINEAluName=AluY
ADediting_1483745chr9_97657227_+SINEAluName=AluY
ADediting_1483746chr9_97657228_+SINEAluName=AluY
ADediting_1483747chr9_97657235_+SINEAluName=AluY
ADediting_1483748chr9_97657240_+SINEAluName=AluY
ADediting_1483749chr9_97657246_+SINEAluName=AluY
ADediting_1483750chr9_97663565_+SINEAluName=AluSx1
ADediting_1483751chr9_97663584_+SINEAluName=AluSx1
ADediting_1483752chr9_97663585_+SINEAluName=AluSx1
ADediting_1483753chr9_97663602_+SINEAluName=AluSx1
ADediting_1483754chr9_97663624_+SINEAluName=AluSx1
ADediting_1483755chr9_97663642_+SINEAluName=AluSx1
ADediting_1483756chr9_97663685_+SINEAluName=AluSx1
ADediting_1483757chr9_97663719_+SINEAluName=AluSx1
ADediting_1483758chr9_97663760_+SINEAluName=AluSx1
ADediting_1483759chr9_97663923_+SINEAluName=AluSz
ADediting_1483760chr9_97663924_+SINEAluName=AluSz
ADediting_1483761chr9_97663929_+SINEAluName=AluSz
ADediting_1483762chr9_97663959_+SINEAluName=AluSz
ADediting_1483763chr9_97663964_+SINEAluName=AluSz
ADediting_1483764chr9_97663965_+SINEAluName=AluSz
ADediting_1483765chr9_97663969_+SINEAluName=AluSz
ADediting_1483766chr9_97663988_+SINEAluName=AluSz
ADediting_1483767chr9_97663997_+SINEAluName=AluSz
ADediting_1483768chr9_97664019_+SINEAluName=AluSz
ADediting_1483769chr9_97664020_+SINEAluName=AluSz
ADediting_1483770chr9_97664023_+SINEAluName=AluSz
ADediting_1483771chr9_97664028_+SINEAluName=AluSz
ADediting_1483772chr9_97664029_+SINEAluName=AluSz
ADediting_1483773chr9_97664040_+SINEAluName=AluSz
ADediting_1483774chr9_97664052_+SINEAluName=AluSz
ADediting_1483775chr9_97664058_+SINEAluName=AluSz
ADediting_1483776chr9_97664059_+SINEAluName=AluSz
ADediting_1483777chr9_97664072_+SINEAluName=AluSz
ADediting_1483778chr9_97664085_+SINEAluName=AluSz
ADediting_1483779chr9_97664099_+SINEAluName=AluSz
ADediting_1483780chr9_97664100_+SINEAluName=AluSz
ADediting_1483781chr9_97664104_+SINEAluName=AluSz
ADediting_1483782chr9_97664154_+SINEAluName=AluSz
ADediting_1483783chr9_97672874_+SINEAluName=AluSc8
ADediting_1483784chr9_97672945_+SINEAluName=AluSc8
ADediting_1483785chr9_97672962_+SINEAluName=AluSc8
ADediting_1483786chr9_97672965_+SINEAluName=AluSc8
ADediting_1483787chr9_97672981_+SINEAluName=AluSc8
ADediting_1483788chr9_97672985_+SINEAluName=AluSc8
ADediting_1483789chr9_97673007_+SINEAluName=AluSc8
ADediting_1483790chr9_97673040_+SINEAluName=AluSc8
ADediting_1483791chr9_97673048_+SINEAluName=AluSc8
ADediting_1483792chr9_97673049_+SINEAluName=AluSc8
ADediting_1483793chr9_97673077_+SINEAluName=AluSc8
ADediting_1483794chr9_97673078_+SINEAluName=AluSc8
ADediting_1594489chr9_97656405_+SINEAluName=AluSx1
ADediting_1594490chr9_97656436_+SINEAluName=AluSx1
ADediting_1594491chr9_97657012_+SINEAluName=AluY
ADediting_1594492chr9_97657024_+SINEAluName=AluY
ADediting_1594493chr9_97663978_+SINEAluName=AluSz
ADediting_1594494chr9_97663983_+SINEAluName=AluSz
ADediting_1594495chr9_97664027_+SINEAluName=AluSz
ADediting_1594496chr9_97664088_+SINEAluName=AluSz
ADediting_1594497chr9_97664091_+SINEAluName=AluSz
ADediting_1674365chr9_97652062_+SINEAluName=AluSx4
ADediting_1674366chr9_97652107_+SINEAluName=AluSx4
ADediting_1674367chr9_97652133_+SINEAluName=AluSx4
ADediting_1674368chr9_97652187_+SINEAluName=AluSx4
ADediting_1674369chr9_97652397_+SINEAluName=AluJb
ADediting_1674370chr9_97652441_+SINEAluName=AluJb
ADediting_1674371chr9_97652553_+SINEAluName=AluJb
ADediting_1674372chr9_97663659_+SINEAluName=AluSx1
ADediting_1674373chr9_97663668_+SINEAluName=AluSx1
ADediting_1674374chr9_97664003_+SINEAluName=AluSz
ADediting_1674375chr9_97664026_+SINEAluName=AluSz

Top

RNA A-to-I editing events in the alternative splicing sites for NCBP1

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

Top

Differntial gene expression between RNA A-to-I edited versus non-edited samples for NCBP1

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
Soverview
Soverview
Soverview
Soverview
Soverview

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
ADeditome IDChrPositoingSkipped exonENSGENSTs

Top

Protein coding region RNA A-to-I editings for NCBP1

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


Top

The effects of the RNA editing to the miRNA binding sites for NCBP1

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1483783chr9_97672874_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-8052chr997672872976728787mer-1a9767286097672878140-24.15
ADediting_1483785chr9_97672962_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-374b-3pchr997672959976729668mer-1a9767294497672966143-11.11
ADediting_1483786chr9_97672965_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-222-5pchr997672959976729668mer-1a9767294397672966146-12.95
ADediting_1483786chr9_97672965_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-30a-3pchr997672961976729688mer-1a9767294497672968150-10.42
ADediting_1483786chr9_97672965_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-30d-3pchr997672961976729688mer-1a9767294297672968149-15.73
ADediting_1483786chr9_97672965_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-30e-3pchr997672961976729688mer-1a9767294497672968150-11.58
ADediting_1483786chr9_97672965_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-936chr997672958976729658mer-1a9767294397672965159-25.95
ADediting_1483787chr9_97672981_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-3190-5pchr997672979976729857mer-m89767296797672986143-15.54
ADediting_1483787chr9_97672981_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-4480chr997672976976729827mer-m89767296397672983140-11.07
ADediting_1483787chr9_97672981_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-548schr997672978976729847mer-m89767296397672985140-10.21
ADediting_1483789chr9_97673007_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-140-3pchr997673002976730087mer-m89767298997673009155-18.82
ADediting_1483790chr9_97673040_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-4431chr997673036976730427mer-m89767302297673043140-16.87
ADediting_1483790chr9_97673040_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-6845-3pchr997673033976730397mer-m89767302097673040155-22.15
ADediting_1483791chr9_97673048_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-9900chr997673046976730527mer-m89767303497673053155-17.58
ADediting_1483792chr9_97673049_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-3155achr997673046976730527mer-m89767303297673053141-23.88
ADediting_1483792chr9_97673049_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-3155bchr997673046976730527mer-m89767303597673053141-22.98
ADediting_1483792chr9_97673049_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-484chr997673046976730527mer-m89767303297673053151-23.09
ADediting_1483793chr9_97673077_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-4638-5pchr997673072976730798mer-1a9767306097673079150-20.28
ADediting_1483794chr9_97673078_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-149-5pchr997673071976730777mer-m89767305397673078155-29.26

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1483783chr9_97672874_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-10399-5pchr997672868976728747mer-m89767285497672875144-10.39
ADediting_1483783chr9_97672874_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-5089-5pchr997672872976728787mer-m89767285797672879148-14.13
ADediting_1483783chr9_97672874_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-6504-3pchr997672868976728747mer-m89767285497672875152-15.11
ADediting_1483784chr9_97672945_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-892achr997672940976729467mer-m89767292797672947140-15.2
ADediting_1483785chr9_97672962_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-6832-5pchr997672956976729627mer-m89767294197672963140-18.87
ADediting_1483787chr9_97672981_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-4794chr997672979976729857mer-m89767296597672986140-12.55
ADediting_1483787chr9_97672981_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-664a-5pchr997672979976729857mer-m89767296397672986146-15.95
ADediting_1483788chr9_97672985_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-4794chr997672979976729857mer-m89767296597672986140-12.55
ADediting_1483788chr9_97672985_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-664a-5pchr997672979976729857mer-m89767296397672986146-15.95
ADediting_1483791chr9_97673048_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-498-5pchr997673042976730487mer-m89767302797673049142-9.71
ADediting_1483792chr9_97673049_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-498-5pchr997673042976730487mer-m89767302797673049142-9.71

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337757chr7_5495852_-ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-589-3pchr997673530976735367mer-m89767351597673537141-18.65
ADediting_1471004chr9_63819627_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-4477bchr997673275976732817mer-m89767326197673282140-13.04
ADediting_1535954chr14_101045974_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-381-3pchr997672121976721288mer-1a9767210697672128168-25.14
ADediting_98288chr1_32086990_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-5585-3pchr997671943976719497mer-m89767193197671950148-13.77

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1097295chr3_85385762_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-5688chr997671449976714568mer-1a9767143597671456140-13.24
ADediting_1391023chr8_140732605_-ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-151a-3pchr997673540976735467mer-m89767352797673547140-16.85
ADediting_1471003chr9_63819626_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-4477bchr997671466976714727mer-m89767145297671473142-6.42
ADediting_1471003chr9_63819626_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-4477bchr997671889976718968mer-1a9767187497671896149-11.48
ADediting_1471004chr9_63819627_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-4477bchr997671466976714727mer-m89767145297671473142-6.42
ADediting_1471004chr9_63819627_+ENSG00000136937.13ENST00000375147.8NCBP1-202hsa-miR-4477bchr997671889976718968mer-1a9767187497671896149-11.48

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for NCBP1

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000375147.8protein_codingSoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_1483783ENST00000375147.8chr9_97672874_+4109-1386.90-1386.90-1388.60
ADediting_1483784ENST00000375147.8chr9_97672945_+4180-1387.70-1386.90-1388.60
ADediting_1483785ENST00000375147.8chr9_97672962_+4197-1390.20-1386.90-1388.60
ADediting_1483786ENST00000375147.8chr9_97672965_+4200-1386.40-1386.90-1388.60
ADediting_1483787ENST00000375147.8chr9_97672981_+4216-1387.20-1386.90-1388.60
ADediting_1483788ENST00000375147.8chr9_97672985_+4220-1386.40-1386.90-1388.60
ADediting_1483789ENST00000375147.8chr9_97673007_+4242-1386.90-1386.90-1388.60
ADediting_1483790ENST00000375147.8chr9_97673040_+4275-1386.10-1386.90-1388.60
ADediting_1483791ENST00000375147.8chr9_97673048_+4283-1386.90-1386.90-1388.60
ADediting_1483792ENST00000375147.8chr9_97673049_+4284-1387.20-1386.90-1388.60
ADediting_1483793ENST00000375147.8chr9_97673077_+4312-1386.20-1386.90-1388.60
ADediting_1483794ENST00000375147.8chr9_97673078_+4313-1386.90-1386.90-1388.60

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for NCBP1

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
CERADediting_1483723chr9_97656348_+2.31571131710901e-120.5325311535821596.49443165891126e-090.4518143234369750.08412023383607780.141503733949401
CERADediting_1483725chr9_97656350_+3.24523123023387e-060.3695975923506290.0003717294074890360.2868886199061870.2900775254798880.0869450194709072
CERADediting_1483728chr9_97656395_+2.60691670362132e-050.3361314947366960.0008493796036199020.2695917646437220.1632032160303010.114433489967972
CERADediting_1483732chr9_97656450_+2.6542397337039e-110.5098999391533861.43632798638367e-060.3817293609651180.3871134670240390.0711213304790929
CERADediting_1483733chr9_97656456_+7.91759146182624e-100.4753412197521915.36161638531202e-060.3618727191436240.8247132175217930.0182353857606915
CERADediting_1483735chr9_97656459_+4.22365376475879e-070.3990789443758683.10513585746882e-050.3331405316465390.7783937006421010.0231679959922107
CERADediting_1483736chr9_97656500_+4.40300320507377e-060.3649272737571350.0002273504484083620.2966783649048140.4267829116365690.065365077940205
CERADediting_1483740chr9_97657106_+9.49883828106447e-060.3528218478666910.000598176518223090.2770679990787540.6173227262511810.0411228622247774
CERADediting_1483741chr9_97657108_+1.05413674628707e-070.4176297853722814.25295524375382e-050.3276817277127240.5886895330218690.044501304757414
DLPFCADediting_1483742chr9_97657148_+0.1254357820471170.08721811656718730.201621675060894-0.07272332027434163.6792003861306e-150.426889342488294
CERADediting_1483742chr9_97657148_+3.54374759019409e-060.3682580331087976.25972634390526e-060.3594489107968670.6979812062486950.0319430402503941
CERADediting_1483744chr9_97657173_+1.75208484037893e-050.3428147946122510.001368015329391460.2590759345520970.7977903102236950.0210934157136406
CERADediting_1483748chr9_97657240_+5.07580282257274e-060.3627253568035373.71864042950531e-050.3300242671036970.4476226508701070.062465443613126
CERADediting_1483749chr9_97657246_+3.3383016653091e-130.5493776430054955.32404450663603e-090.4541135918838120.1704494469837070.112507662089133
CERADediting_1483757chr9_97663719_+0.009256368327952120.2118429837808946.96044084177414e-050.3189182304786940.484019722947056-0.0575769067732631
CERADediting_1483782chr9_97664154_+0.001248052835729650.2611341315458168.2277573342001e-070.3897500668817270.02742365175446090.180104422161066

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC8.04574511599823e-200.4864637901170181.80045168786259e-210.5050487329446496.65677024770972e-050.224524673659192
AC6.81935301709354e-760.8640749238284526.09293831220134e-410.7182212748668311.1901970185613e-240.588089905799471
PCC3.85924337573881e-430.7963709191194231.43070593390847e-370.762387602006854.57649710738455e-070.355274681514166
CER1.47247805286647e-400.836833586534112.28287369629721e-160.6053914143750490.009487934910264650.211168028266376
TCX3.36061432639475e-320.7820583302247367.77862242263647e-090.4497116959141351.13155433559665e-070.416709237810122
FP4.52678651608306e-300.7229378014432415.4502113123679e-290.7134570731792774.89113850835847e-050.299462622554628
IFG7.14688964052638e-070.8146853922708184.22588997515952e-050.7244260279676630.0133680473962470.487833838743338
PG1.28403759932172e-570.8672187782402986.59036692766902e-300.7106318244811750.4421177899567620.056694940958306
STG2.59196823759184e-180.7791764369762569.41787806817834e-130.6817519071666080.02966345290308980.237417307146159

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Relation with AD stages for NCBP1

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
IFGADediting_1483764chr9_97663965_+0.03547133699799280.422303326441651

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
TCX2.14932464445327e-060.44162326793736

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RelatedDrugs for NCBP1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for NCBP1

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource