ADeditome: functional annotation of RNA A-to-I editing in AD

Gene summary for MRE11

Gene summary

Gene information	Gene symbol	MRE11
	Gene ID	4361
	Gene name	MRE11 homolog, double strand break repair nuclease
	Synonyms	ATLD\|HNGS1\|MRE11A\|MRE11B
	Cytomap	11q21
	Type of gene	protein-coding
	Description	double-strand break repair protein MRE11AT-like diseaseDNA recombination and repair proteinMRE11 double strand break repair nuclease AMRE11 homolog 1MRE11 homolog A, double strand break repair nucleaseMRE11 homolog, double strand break repair nuclea
	Modification date	20200315
	UniProtAcc	P49959,
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
MRE11	GO:0000724	double-strand break repair via homologous recombination	29670289\|30612738
MRE11	GO:0006303	double-strand break repair via nonhomologous end joining	9651580
MRE11	GO:0006974	cellular response to DNA damage stimulus	17500065\|29670289
MRE11	GO:0031954	positive regulation of protein autophosphorylation	15790808
MRE11	GO:0033674	positive regulation of kinase activity	15790808
MRE11	GO:0110025	DNA strand resection involved in replication fork processing	29670289

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RNA A-to-I events for MRE11

RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA editing frequencies across three data sets.

The number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA A-to-I editing events in AD.

ADediting_292134(94415841, -), ADediting_292135(94415844, -), ADediting_292136(94415873, -), ADediting_292137(94415876, -), ADediting_292138(94415889, -), ADediting_292139(94415922, -), ADediting_292140(94415935, -), ADediting_292141(94415939, -), ADediting_292142(94415942, -), ADediting_292143(94415943, -), ADediting_292144(94415948, -), ADediting_292145(94415949, -), ADediting_292146(94415967, -), ADediting_292147(94415971, -), ADediting_292148(94415975, -), ADediting_292149(94415990, -), ADediting_292150(94416004, -), ADediting_292151(94416014, -), ADediting_292152(94416015, -), ADediting_292153(94416024, -), ADediting_292154(94416038, -), ADediting_292155(94416057, -), ADediting_292156(94416060, -), ADediting_292157(94416062, -), ADediting_292158(94416075, -), ADediting_292159(94416092, -), ADediting_292160(94416573, -), ADediting_292161(94416580, -), ADediting_292162(94416589, -), ADediting_292163(94416601, -), ADediting_292164(94416602, -), ADediting_292165(94416603, -), ADediting_292166(94416611, -), ADediting_292167(94416616, -), ADediting_292168(94416620, -), ADediting_292169(94416624, -), ADediting_292170(94416632, -), ADediting_292171(94416652, -), ADediting_292172(94416656, -), ADediting_292173(94416672, -), ADediting_292174(94416678, -), ADediting_292175(94416681, -), ADediting_292176(94416687, -), ADediting_292177(94416734, -), ADediting_292178(94416736, -), ADediting_292179(94416746, -), ADediting_292180(94416749, -), ADediting_292181(94416750, -), ADediting_292182(94416758, -), ADediting_292183(94416798, -), ADediting_292184(94416801, -), ADediting_292185(94416807, -), ADediting_292186(94416812, -), ADediting_292187(94417003, -), ADediting_292188(94417004, -), ADediting_292189(94417005, -), ADediting_292190(94417009, -), ADediting_292191(94417044, -), ADediting_292192(94417053, -), ADediting_292193(94417088, -), ADediting_292194(94417101, -), ADediting_292195(94417105, -), ADediting_292196(94417109, -), ADediting_292197(94417114, -), ADediting_292198(94417115, -), ADediting_292199(94417133, -), ADediting_292200(94417141, -), ADediting_292201(94417146, -), ADediting_292202(94417151, -), ADediting_292203(94417155, -), ADediting_292204(94417171, -), ADediting_292205(94417172, -), ADediting_292206(94417173, -), ADediting_292207(94417181, -), ADediting_292208(94417182, -), ADediting_292209(94417191, -), ADediting_292210(94417196, -), ADediting_292211(94417202, -), ADediting_292212(94417205, -), ADediting_292213(94417210, -), ADediting_292214(94417227, -), ADediting_292215(94417241, -), ADediting_292216(94417244, -), ADediting_292217(94417249, -), ADediting_292218(94417250, -), ADediting_292219(94417258, -), ADediting_292220(94417266, -), ADediting_292221(94417279, -), ADediting_292222(94417288, -), ADediting_292223(94417289, -), ADediting_292224(94418564, -), ADediting_292225(94420776, -), ADediting_292226(94420980, -), ADediting_292227(94420988, -), ADediting_292228(94422782, -), ADediting_292229(94422838, -), ADediting_292230(94422851, -), ADediting_292231(94422999, -), ADediting_292270(94437868, -), ADediting_292302(94461831, -), ADediting_292303(94461894, -), ADediting_292304(94461953, -), ADediting_292305(94461999, -), ADediting_292306(94462069, -), ADediting_292307(94465481, -), ADediting_292308(94465533, -), ADediting_292309(94465668, -), ADediting_292310(94468361, -), ADediting_292311(94468409, -), ADediting_292312(94468410, -), ADediting_292313(94468417, -), ADediting_292314(94468425, -), ADediting_292315(94468619, -), ADediting_292316(94468621, -), ADediting_292317(94468622, -), ADediting_292318(94468628, -), ADediting_292319(94468633, -), ADediting_292320(94468634, -), ADediting_292321(94468637, -), ADediting_292322(94468638, -), ADediting_292323(94468646, -), ADediting_292324(94468653, -), ADediting_292325(94468656, -), ADediting_292326(94468661, -), ADediting_292327(94468662, -), ADediting_1529402(94415926, -), ADediting_1529403(94415932, -), ADediting_1529404(94416005, -), ADediting_1529405(94417011, -), ADediting_1529406(94417160, -), ADediting_1529407(94428607, -), ADediting_1529408(94461925, -), ADediting_1529409(94468412, -), ADediting_1529410(94485168, -), ADediting_1529411(94485218, -), ADediting_1611359(94415984, -), ADediting_1611360(94416723, -), ADediting_1611361(94468620, -), ADediting_1611362(94485636, -), ADediting_1611363(94485649, -),

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RNA editing positional annotations for MRE11 using Annovar

Protein coding RNA editing(s).

ADeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

ADeditome ID	Position	Variant type
ADediting_292134	chr11_94415841_-	UTR3
ADediting_292135	chr11_94415844_-	UTR3
ADediting_292136	chr11_94415873_-	UTR3
ADediting_292137	chr11_94415876_-	UTR3
ADediting_292138	chr11_94415889_-	UTR3
ADediting_292139	chr11_94415922_-	UTR3
ADediting_292140	chr11_94415935_-	UTR3
ADediting_292141	chr11_94415939_-	UTR3
ADediting_292142	chr11_94415942_-	UTR3
ADediting_292143	chr11_94415943_-	UTR3
ADediting_292144	chr11_94415948_-	UTR3
ADediting_292145	chr11_94415949_-	UTR3
ADediting_292146	chr11_94415967_-	UTR3
ADediting_292147	chr11_94415971_-	UTR3
ADediting_292148	chr11_94415975_-	UTR3
ADediting_292149	chr11_94415990_-	UTR3
ADediting_292150	chr11_94416004_-	UTR3
ADediting_292151	chr11_94416014_-	UTR3
ADediting_292152	chr11_94416015_-	UTR3
ADediting_292153	chr11_94416024_-	UTR3
ADediting_292154	chr11_94416038_-	UTR3
ADediting_292155	chr11_94416057_-	UTR3
ADediting_292156	chr11_94416060_-	UTR3
ADediting_292157	chr11_94416062_-	UTR3
ADediting_292158	chr11_94416075_-	UTR3
ADediting_292159	chr11_94416092_-	UTR3
ADediting_292160	chr11_94416573_-	UTR3
ADediting_292161	chr11_94416580_-	UTR3
ADediting_292162	chr11_94416589_-	UTR3
ADediting_292163	chr11_94416601_-	UTR3
ADediting_292164	chr11_94416602_-	UTR3
ADediting_292165	chr11_94416603_-	UTR3
ADediting_292166	chr11_94416611_-	UTR3
ADediting_292167	chr11_94416616_-	UTR3
ADediting_292168	chr11_94416620_-	UTR3
ADediting_292169	chr11_94416624_-	UTR3
ADediting_292170	chr11_94416632_-	UTR3
ADediting_292171	chr11_94416652_-	UTR3
ADediting_292172	chr11_94416656_-	UTR3
ADediting_292173	chr11_94416672_-	UTR3
ADediting_292174	chr11_94416678_-	UTR3
ADediting_292175	chr11_94416681_-	UTR3
ADediting_292176	chr11_94416687_-	UTR3
ADediting_292177	chr11_94416734_-	UTR3
ADediting_292178	chr11_94416736_-	UTR3
ADediting_292179	chr11_94416746_-	UTR3
ADediting_292180	chr11_94416749_-	UTR3
ADediting_292181	chr11_94416750_-	UTR3
ADediting_292182	chr11_94416758_-	UTR3
ADediting_292183	chr11_94416798_-	UTR3
ADediting_292184	chr11_94416801_-	UTR3
ADediting_292185	chr11_94416807_-	UTR3
ADediting_292186	chr11_94416812_-	UTR3
ADediting_292187	chr11_94417003_-	UTR3
ADediting_292188	chr11_94417004_-	UTR3
ADediting_292189	chr11_94417005_-	UTR3
ADediting_292190	chr11_94417009_-	UTR3
ADediting_292191	chr11_94417044_-	UTR3
ADediting_292192	chr11_94417053_-	UTR3
ADediting_292193	chr11_94417088_-	UTR3
ADediting_292194	chr11_94417101_-	UTR3
ADediting_292195	chr11_94417105_-	UTR3
ADediting_292196	chr11_94417109_-	UTR3
ADediting_292197	chr11_94417114_-	UTR3
ADediting_292198	chr11_94417115_-	UTR3
ADediting_292199	chr11_94417133_-	UTR3
ADediting_292200	chr11_94417141_-	UTR3
ADediting_292201	chr11_94417146_-	UTR3
ADediting_292202	chr11_94417151_-	UTR3
ADediting_292203	chr11_94417155_-	UTR3
ADediting_292204	chr11_94417171_-	UTR3
ADediting_292205	chr11_94417172_-	UTR3
ADediting_292206	chr11_94417173_-	UTR3
ADediting_292207	chr11_94417181_-	UTR3
ADediting_292208	chr11_94417182_-	UTR3
ADediting_292209	chr11_94417191_-	UTR3
ADediting_292210	chr11_94417196_-	UTR3
ADediting_292211	chr11_94417202_-	UTR3
ADediting_292212	chr11_94417205_-	UTR3
ADediting_292213	chr11_94417210_-	UTR3
ADediting_292214	chr11_94417227_-	UTR3
ADediting_292215	chr11_94417241_-	UTR3
ADediting_292216	chr11_94417244_-	UTR3
ADediting_292217	chr11_94417249_-	UTR3
ADediting_292218	chr11_94417250_-	UTR3
ADediting_292219	chr11_94417258_-	UTR3
ADediting_292220	chr11_94417266_-	UTR3
ADediting_292221	chr11_94417279_-	UTR3
ADediting_292222	chr11_94417288_-	UTR3
ADediting_292223	chr11_94417289_-	UTR3
ADediting_292224	chr11_94418564_-	UTR3
ADediting_292225	chr11_94420776_-	intronic
ADediting_292226	chr11_94420980_-	intronic
ADediting_292227	chr11_94420988_-	intronic
ADediting_292228	chr11_94422782_-	intronic
ADediting_292229	chr11_94422838_-	intronic
ADediting_292230	chr11_94422851_-	intronic
ADediting_292231	chr11_94422999_-	intronic
ADediting_292270	chr11_94437868_-	intronic
ADediting_292302	chr11_94461831_-	intronic
ADediting_292303	chr11_94461894_-	intronic
ADediting_292304	chr11_94461953_-	intronic
ADediting_292305	chr11_94461999_-	intronic
ADediting_292306	chr11_94462069_-	intronic
ADediting_292307	chr11_94465481_-	intronic
ADediting_292308	chr11_94465533_-	intronic
ADediting_292309	chr11_94465668_-	intronic
ADediting_292310	chr11_94468361_-	intronic
ADediting_292311	chr11_94468409_-	intronic
ADediting_292312	chr11_94468410_-	intronic
ADediting_292313	chr11_94468417_-	intronic
ADediting_292314	chr11_94468425_-	intronic
ADediting_292315	chr11_94468619_-	intronic
ADediting_292316	chr11_94468621_-	intronic
ADediting_292317	chr11_94468622_-	intronic
ADediting_292318	chr11_94468628_-	intronic
ADediting_292319	chr11_94468633_-	intronic
ADediting_292320	chr11_94468634_-	intronic
ADediting_292321	chr11_94468637_-	intronic
ADediting_292322	chr11_94468638_-	intronic
ADediting_292323	chr11_94468646_-	intronic
ADediting_292324	chr11_94468653_-	intronic
ADediting_292325	chr11_94468656_-	intronic
ADediting_292326	chr11_94468661_-	intronic
ADediting_292327	chr11_94468662_-	intronic
ADediting_1529402	chr11_94415926_-	UTR3
ADediting_1529403	chr11_94415932_-	UTR3
ADediting_1529404	chr11_94416005_-	UTR3
ADediting_1529405	chr11_94417011_-	UTR3
ADediting_1529406	chr11_94417160_-	UTR3
ADediting_1529407	chr11_94428607_-	intronic
ADediting_1529408	chr11_94461925_-	intronic
ADediting_1529409	chr11_94468412_-	intronic
ADediting_1529410	chr11_94485168_-	intronic
ADediting_1529411	chr11_94485218_-	intronic
ADediting_1611359	chr11_94415984_-	UTR3
ADediting_1611360	chr11_94416723_-	UTR3
ADediting_1611361	chr11_94468620_-	intronic
ADediting_1611362	chr11_94485636_-	intronic
ADediting_1611363	chr11_94485649_-	intronic

Repat-regional RNA editing(s).

ADeditome ID	Position	Repeat family	Repeat sub family	Repeat name
ADediting_292134	chr11_94415841_-	SINE	Alu	Name=AluSx1
ADediting_292135	chr11_94415844_-	SINE	Alu	Name=AluSx1
ADediting_292136	chr11_94415873_-	SINE	Alu	Name=AluSx1
ADediting_292137	chr11_94415876_-	SINE	Alu	Name=AluSx1
ADediting_292138	chr11_94415889_-	SINE	Alu	Name=AluSx1
ADediting_292139	chr11_94415922_-	SINE	Alu	Name=AluSx1
ADediting_292140	chr11_94415935_-	SINE	Alu	Name=AluSx1
ADediting_292141	chr11_94415939_-	SINE	Alu	Name=AluSx1
ADediting_292142	chr11_94415942_-	SINE	Alu	Name=AluSx1
ADediting_292143	chr11_94415943_-	SINE	Alu	Name=AluSx1
ADediting_292144	chr11_94415948_-	SINE	Alu	Name=AluSx1
ADediting_292145	chr11_94415949_-	SINE	Alu	Name=AluSx1
ADediting_292146	chr11_94415967_-	SINE	Alu	Name=AluSx1
ADediting_292147	chr11_94415971_-	SINE	Alu	Name=AluSx1
ADediting_292148	chr11_94415975_-	SINE	Alu	Name=AluSx1
ADediting_292149	chr11_94415990_-	SINE	Alu	Name=AluSx1
ADediting_292150	chr11_94416004_-	SINE	Alu	Name=AluSx1
ADediting_292151	chr11_94416014_-	SINE	Alu	Name=AluSx1
ADediting_292152	chr11_94416015_-	SINE	Alu	Name=AluSx1
ADediting_292153	chr11_94416024_-	SINE	Alu	Name=AluSx1
ADediting_292154	chr11_94416038_-	SINE	Alu	Name=AluSx1
ADediting_292155	chr11_94416057_-	SINE	Alu	Name=AluSx1
ADediting_292156	chr11_94416060_-	SINE	Alu	Name=AluSx1
ADediting_292157	chr11_94416062_-	SINE	Alu	Name=AluSx1
ADediting_292158	chr11_94416075_-	SINE	Alu	Name=AluSx1
ADediting_292159	chr11_94416092_-	SINE	Alu	Name=AluSx1
ADediting_292160	chr11_94416573_-	SINE	Alu	Name=AluYm1
ADediting_292161	chr11_94416580_-	SINE	Alu	Name=AluYm1
ADediting_292162	chr11_94416589_-	SINE	Alu	Name=AluYm1
ADediting_292163	chr11_94416601_-	SINE	Alu	Name=AluYm1
ADediting_292164	chr11_94416602_-	SINE	Alu	Name=AluYm1
ADediting_292165	chr11_94416603_-	SINE	Alu	Name=AluYm1
ADediting_292166	chr11_94416611_-	SINE	Alu	Name=AluYm1
ADediting_292167	chr11_94416616_-	SINE	Alu	Name=AluYm1
ADediting_292168	chr11_94416620_-	SINE	Alu	Name=AluYm1
ADediting_292169	chr11_94416624_-	SINE	Alu	Name=AluYm1
ADediting_292170	chr11_94416632_-	SINE	Alu	Name=AluYm1
ADediting_292171	chr11_94416652_-	SINE	Alu	Name=AluYm1
ADediting_292172	chr11_94416656_-	SINE	Alu	Name=AluYm1
ADediting_292173	chr11_94416672_-	SINE	Alu	Name=AluYm1
ADediting_292174	chr11_94416678_-	SINE	Alu	Name=AluYm1
ADediting_292175	chr11_94416681_-	SINE	Alu	Name=AluYm1
ADediting_292176	chr11_94416687_-	SINE	Alu	Name=AluYm1
ADediting_292177	chr11_94416734_-	SINE	Alu	Name=AluYm1
ADediting_292178	chr11_94416736_-	SINE	Alu	Name=AluYm1
ADediting_292179	chr11_94416746_-	SINE	Alu	Name=AluYm1
ADediting_292180	chr11_94416749_-	SINE	Alu	Name=AluYm1
ADediting_292181	chr11_94416750_-	SINE	Alu	Name=AluYm1
ADediting_292182	chr11_94416758_-	SINE	Alu	Name=AluYm1
ADediting_292183	chr11_94416798_-	SINE	Alu	Name=AluYm1
ADediting_292184	chr11_94416801_-	SINE	Alu	Name=AluYm1
ADediting_292185	chr11_94416807_-	SINE	Alu	Name=AluYm1
ADediting_292186	chr11_94416812_-	SINE	Alu	Name=AluYm1
ADediting_292187	chr11_94417003_-	SINE	Alu	Name=AluSq2
ADediting_292188	chr11_94417004_-	SINE	Alu	Name=AluSq2
ADediting_292189	chr11_94417005_-	SINE	Alu	Name=AluSq2
ADediting_292190	chr11_94417009_-	SINE	Alu	Name=AluSq2
ADediting_292191	chr11_94417044_-	SINE	Alu	Name=AluSq2
ADediting_292192	chr11_94417053_-	SINE	Alu	Name=AluSq2
ADediting_292193	chr11_94417088_-	SINE	Alu	Name=AluSq2
ADediting_292194	chr11_94417101_-	SINE	Alu	Name=AluSq2
ADediting_292195	chr11_94417105_-	SINE	Alu	Name=AluSq2
ADediting_292196	chr11_94417109_-	SINE	Alu	Name=AluSq2
ADediting_292197	chr11_94417114_-	SINE	Alu	Name=AluSq2
ADediting_292198	chr11_94417115_-	SINE	Alu	Name=AluSq2
ADediting_292199	chr11_94417133_-	SINE	Alu	Name=AluSq2
ADediting_292200	chr11_94417141_-	SINE	Alu	Name=AluSq2
ADediting_292201	chr11_94417146_-	SINE	Alu	Name=AluSq2
ADediting_292202	chr11_94417151_-	SINE	Alu	Name=AluSq2
ADediting_292203	chr11_94417155_-	SINE	Alu	Name=AluSq2
ADediting_292204	chr11_94417171_-	SINE	Alu	Name=AluSq2
ADediting_292205	chr11_94417172_-	SINE	Alu	Name=AluSq2
ADediting_292206	chr11_94417173_-	SINE	Alu	Name=AluSq2
ADediting_292207	chr11_94417181_-	SINE	Alu	Name=AluSq2
ADediting_292208	chr11_94417182_-	SINE	Alu	Name=AluSq2
ADediting_292209	chr11_94417191_-	SINE	Alu	Name=AluSq2
ADediting_292210	chr11_94417196_-	SINE	Alu	Name=AluSq2
ADediting_292211	chr11_94417202_-	SINE	Alu	Name=AluSq2
ADediting_292212	chr11_94417205_-	SINE	Alu	Name=AluSq2
ADediting_292213	chr11_94417210_-	SINE	Alu	Name=AluSq2
ADediting_292214	chr11_94417227_-	SINE	Alu	Name=AluSq2
ADediting_292215	chr11_94417241_-	SINE	Alu	Name=AluSq2
ADediting_292216	chr11_94417244_-	SINE	Alu	Name=AluSq2
ADediting_292217	chr11_94417249_-	SINE	Alu	Name=AluSq2
ADediting_292218	chr11_94417250_-	SINE	Alu	Name=AluSq2
ADediting_292219	chr11_94417258_-	SINE	Alu	Name=AluSq2
ADediting_292220	chr11_94417266_-	SINE	Alu	Name=AluSq2
ADediting_292225	chr11_94420776_-	SINE	Alu	Name=AluY
ADediting_292226	chr11_94420980_-	SINE	Alu	Name=AluY
ADediting_292227	chr11_94420988_-	SINE	Alu	Name=AluY
ADediting_292228	chr11_94422782_-	SINE	Alu	Name=AluSp
ADediting_292229	chr11_94422838_-	SINE	Alu	Name=AluSp
ADediting_292230	chr11_94422851_-	SINE	Alu	Name=AluSp
ADediting_292231	chr11_94422999_-	SINE	Alu	Name=AluSp
ADediting_292270	chr11_94437868_-	SINE	Alu	Name=AluSx1
ADediting_292302	chr11_94461831_-	SINE	Alu	Name=AluY
ADediting_292303	chr11_94461894_-	SINE	Alu	Name=AluY
ADediting_292304	chr11_94461953_-	SINE	Alu	Name=AluY
ADediting_292305	chr11_94461999_-	SINE	Alu	Name=AluY
ADediting_292306	chr11_94462069_-	SINE	Alu	Name=AluY
ADediting_292307	chr11_94465481_-	SINE	Alu	Name=AluSx
ADediting_292308	chr11_94465533_-	SINE	Alu	Name=AluSx
ADediting_292309	chr11_94465668_-	SINE	Alu	Name=AluSx
ADediting_1529402	chr11_94415926_-	SINE	Alu	Name=AluSx1
ADediting_1529403	chr11_94415932_-	SINE	Alu	Name=AluSx1
ADediting_1529404	chr11_94416005_-	SINE	Alu	Name=AluSx1
ADediting_1529405	chr11_94417011_-	SINE	Alu	Name=AluSq2
ADediting_1529406	chr11_94417160_-	SINE	Alu	Name=AluSq2
ADediting_1529407	chr11_94428607_-	SINE	Alu	Name=AluSx3
ADediting_1529408	chr11_94461925_-	SINE	Alu	Name=AluY
ADediting_1529410	chr11_94485168_-	SINE	Alu	Name=AluSx1
ADediting_1529411	chr11_94485218_-	SINE	Alu	Name=AluSx1
ADediting_1611359	chr11_94415984_-	SINE	Alu	Name=AluSx1
ADediting_1611360	chr11_94416723_-	SINE	Alu	Name=AluYm1
ADediting_1611362	chr11_94485636_-	SINE	Alu	Name=AluSx3
ADediting_1611363	chr11_94485649_-	SINE	Alu	Name=AluSx3

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RNA A-to-I editing events in the alternative splicing sites for MRE11

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

ADeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for MRE11

Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

- Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

ADeditome ID

Chr

Positoing

Skipped exon

ENSG

ENSTs

Top

Protein coding region RNA A-to-I editings for MRE11

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

Top

The effects of the RNA editing to the miRNA binding sites for MRE11

RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

ADeditom_ID	Position	ENSG	ENST	Transcript name	miRNA ID	Chromosome	Targt	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
ADediting_1529402	chr11_94415926_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-1913	chr11	94415921	94415927	7mer-m8	94415920	94415939	148	-25.01
ADediting_1529402	chr11_94415926_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6849-3p	chr11	94415926	94415932	7mer-m8	94415925	94415946	140	-14.45
ADediting_1529403	chr11_94415932_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-125a-5p	chr11	94415932	94415938	7mer-m8	94415931	94415954	140	-16.11
ADediting_1529403	chr11_94415932_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-125b-5p	chr11	94415932	94415938	7mer-m8	94415931	94415952	140	-16.11
ADediting_1529403	chr11_94415932_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-3943	chr11	94415928	94415934	7mer-m8	94415927	94415947	154	-21.55
ADediting_1529403	chr11_94415932_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4313	chr11	94415929	94415935	7mer-m8	94415928	94415947	146	-21.1
ADediting_1529403	chr11_94415932_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4319	chr11	94415932	94415938	7mer-m8	94415931	94415947	142	-16.15
ADediting_1529405	chr11_94417011_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-367-5p	chr11	94417011	94417017	7mer-m8	94417010	94417032	148	-15.78
ADediting_1529405	chr11_94417011_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-483-3p	chr11	94417005	94417012	8mer-1a	94417005	94417025	151	-19.76
ADediting_1529406	chr11_94417160_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-374b-3p	chr11	94417155	94417162	8mer-1a	94417155	94417177	147	-13.29
ADediting_1611359	chr11_94415984_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-153-5p	chr11	94415984	94415990	7mer-m8	94415983	94416005	152	-12.12
ADediting_1611359	chr11_94415984_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-3680-3p	chr11	94415979	94415986	8mer-1a	94415979	94416001	140	-16.5
ADediting_1611360	chr11_94416723_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6786-5p	chr11	94416723	94416729	7mer-m8	94416722	94416743	151	-27.13
ADediting_292135	chr11_94415844_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-874-3p	chr11	94415840	94415847	8mer-1a	94415840	94415862	153	-24.75
ADediting_292136	chr11_94415873_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4634	chr11	94415868	94415875	8mer-1a	94415868	94415888	143	-21.29
ADediting_292137	chr11_94415876_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-3913-3p	chr11	94415873	94415880	8mer-1a	94415873	94415893	148	-11.49
ADediting_292137	chr11_94415876_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-489-3p	chr11	94415873	94415879	7mer-m8	94415872	94415892	148	-17.91
ADediting_292142	chr11_94415942_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6506-5p	chr11	94415942	94415948	7mer-m8	94415941	94415963	144	-15.06
ADediting_292145	chr11_94415949_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-513a-5p	chr11	94415948	94415954	7mer-m8	94415947	94415964	140	-14.76
ADediting_292145	chr11_94415949_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-638	chr11	94415943	94415949	7mer-1a	94415943	94415967	151	-32.44
ADediting_292148	chr11_94415975_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-3190-5p	chr11	94415970	94415976	7mer-m8	94415969	94415988	143	-16.24
ADediting_292148	chr11_94415975_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-548s	chr11	94415971	94415977	7mer-m8	94415970	94415992	145	-11.19
ADediting_292149	chr11_94415990_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-222-5p	chr11	94415988	94415995	8mer-1a	94415988	94416007	142	-9.79
ADediting_292149	chr11_94415990_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-30a-3p	chr11	94415986	94415993	8mer-1a	94415986	94416005	146	-9.57
ADediting_292149	chr11_94415990_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-30d-3p	chr11	94415986	94415993	8mer-1a	94415986	94416005	150	-11.06
ADediting_292149	chr11_94415990_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-30e-3p	chr11	94415986	94415993	8mer-1a	94415986	94416007	145	-11.28
ADediting_292149	chr11_94415990_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-936	chr11	94415989	94415996	8mer-1a	94415989	94416011	159	-24.49
ADediting_292150	chr11_94416004_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4508	chr11	94415998	94416005	8mer-1a	94415998	94416014	144	-23.81
ADediting_292156	chr11_94416060_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-212-5p	chr11	94416059	94416065	7mer-m8	94416058	94416082	162	-21.87
ADediting_292156	chr11_94416060_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6747-3p	chr11	94416055	94416061	7mer-m8	94416054	94416075	154	-22.42
ADediting_292158	chr11_94416075_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-518a-3p	chr11	94416071	94416077	7mer-m8	94416070	94416091	145	-14.97
ADediting_292158	chr11_94416075_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-518b	chr11	94416071	94416077	7mer-m8	94416070	94416091	145	-21.72
ADediting_292158	chr11_94416075_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-518c-3p	chr11	94416071	94416077	7mer-m8	94416070	94416092	145	-21.64
ADediting_292158	chr11_94416075_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-518d-3p	chr11	94416071	94416077	7mer-m8	94416070	94416090	145	-17.1
ADediting_292158	chr11_94416075_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-518e-3p	chr11	94416072	94416078	7mer-m8	94416071	94416090	141	-17.33
ADediting_292158	chr11_94416075_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-518f-3p	chr11	94416071	94416077	7mer-m8	94416070	94416090	145	-18.08
ADediting_292158	chr11_94416075_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-526a-3p	chr11	94416071	94416077	7mer-m8	94416070	94416091	145	-18.31
ADediting_292159	chr11_94416092_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4634	chr11	94416088	94416094	7mer-m8	94416087	94416110	155	-34.3
ADediting_292160	chr11_94416573_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-10394-3p	chr11	94416567	94416574	8mer-1a	94416567	94416594	154	-31.01
ADediting_292160	chr11_94416573_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-3178	chr11	94416567	94416574	8mer-1a	94416567	94416583	145	-25.09
ADediting_292161	chr11_94416580_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-663b	chr11	94416575	94416581	7mer-m8	94416574	94416595	155	-32.24
ADediting_292163	chr11_94416601_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-3189-3p	chr11	94416600	94416606	7mer-m8	94416599	94416622	157	-25.36
ADediting_292163	chr11_94416601_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6813-3p	chr11	94416599	94416605	7mer-m8	94416598	94416618	140	-10.68
ADediting_292164	chr11_94416602_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-326	chr11	94416600	94416606	7mer-m8	94416599	94416618	140	-13.25
ADediting_292164	chr11_94416602_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-330-5p	chr11	94416600	94416606	7mer-m8	94416599	94416622	141	-19.11
ADediting_292164	chr11_94416602_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4314	chr11	94416601	94416607	7mer-m8	94416600	94416618	141	-20.85
ADediting_292164	chr11_94416602_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-514a-5p	chr11	94416599	94416605	7mer-m8	94416598	94416621	150	-18.62
ADediting_292165	chr11_94416603_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6771-5p	chr11	94416601	94416608	8mer-1a	94416601	94416620	148	-23.97
ADediting_292167	chr11_94416616_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6765-5p	chr11	94416611	94416617	7mer-m8	94416610	94416637	154	-28.08
ADediting_292168	chr11_94416620_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-1228-5p	chr11	94416616	94416622	7mer-m8	94416615	94416635	147	-27.44
ADediting_292169	chr11_94416624_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4776-5p	chr11	94416620	94416626	7mer-m8	94416619	94416640	160	-25.52
ADediting_292169	chr11_94416624_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4800-5p	chr11	94416619	94416625	7mer-m8	94416618	94416641	151	-25.1
ADediting_292170	chr11_94416632_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-3922-5p	chr11	94416627	94416633	7mer-m8	94416626	94416649	162	-26.46
ADediting_292170	chr11_94416632_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4753-5p	chr11	94416628	94416634	7mer-m8	94416627	94416649	155	-24.93
ADediting_292172	chr11_94416656_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-3190-5p	chr11	94416651	94416657	7mer-m8	94416650	94416668	148	-20.6
ADediting_292172	chr11_94416656_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-548s	chr11	94416652	94416658	7mer-m8	94416651	94416673	152	-15.46
ADediting_292173	chr11_94416672_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-340-3p	chr11	94416671	94416677	7mer-m8	94416670	94416691	149	-17.74
ADediting_292173	chr11_94416672_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6827-3p	chr11	94416671	94416677	7mer-m8	94416670	94416690	153	-17.53
ADediting_292178	chr11_94416736_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-17-3p	chr11	94416733	94416739	7mer-m8	94416732	94416754	158	-20.42
ADediting_292179	chr11_94416746_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-3614-5p	chr11	94416746	94416752	7mer-m8	94416745	94416768	152	-25.27
ADediting_292179	chr11_94416746_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4691-3p	chr11	94416742	94416748	7mer-m8	94416741	94416768	150	-26.36
ADediting_292181	chr11_94416750_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6771-5p	chr11	94416749	94416755	7mer-m8	94416748	94416767	160	-34.33
ADediting_292182	chr11_94416758_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6089	chr11	94416753	94416759	7mer-m8	94416752	94416776	169	-44.06
ADediting_292183	chr11_94416798_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-553	chr11	94416795	94416801	7mer-m8	94416794	94416814	145	-20.37
ADediting_292184	chr11_94416801_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-652-3p	chr11	94416797	94416803	7mer-m8	94416796	94416816	152	-18.58
ADediting_292184	chr11_94416801_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6789-3p	chr11	94416798	94416805	8mer-1a	94416798	94416816	160	-33.77
ADediting_292185	chr11_94416807_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-7108-3p	chr11	94416805	94416811	7mer-m8	94416804	94416823	147	-22.2
ADediting_292186	chr11_94416812_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-361-3p	chr11	94416810	94416816	7mer-m8	94416809	94416831	140	-19.78
ADediting_292186	chr11_94416812_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4313	chr11	94416807	94416813	7mer-1a	94416807	94416826	140	-23.85
ADediting_292187	chr11_94417003_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6837-3p	chr11	94417003	94417009	7mer-m8	94417002	94417028	151	-23.93
ADediting_292188	chr11_94417004_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-627-5p	chr11	94416998	94417005	8mer-1a	94416998	94417019	145	-12.74
ADediting_292189	chr11_94417005_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4436b-5p	chr11	94417003	94417009	7mer-1a	94417003	94417023	146	-21.79
ADediting_292189	chr11_94417005_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6777-3p	chr11	94417004	94417011	8mer-1a	94417004	94417023	156	-24.17
ADediting_292190	chr11_94417009_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6780b-3p	chr11	94417008	94417014	7mer-m8	94417007	94417027	145	-15.72
ADediting_292195	chr11_94417105_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-646	chr11	94417103	94417109	7mer-m8	94417102	94417120	141	-13.47
ADediting_292196	chr11_94417109_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4662a-5p	chr11	94417105	94417111	7mer-m8	94417104	94417125	143	-7.03
ADediting_292197	chr11_94417114_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-499a-5p	chr11	94417109	94417115	7mer-m8	94417108	94417127	149	-14.65
ADediting_292198	chr11_94417115_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-513a-5p	chr11	94417114	94417120	7mer-m8	94417113	94417130	148	-17.65
ADediting_292201	chr11_94417146_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-500a-5p	chr11	94417141	94417148	8mer-1a	94417141	94417163	144	-11.72
ADediting_292201	chr11_94417146_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-501-5p	chr11	94417143	94417149	7mer-m8	94417142	94417163	150	-14.96
ADediting_292202	chr11_94417151_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-153-5p	chr11	94417151	94417157	7mer-m8	94417150	94417171	145	-9.63
ADediting_292202	chr11_94417151_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-3680-3p	chr11	94417146	94417153	8mer-1a	94417146	94417168	140	-13.99
ADediting_292203	chr11_94417155_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-630	chr11	94417149	94417156	8mer-1a	94417149	94417169	158	-12.84
ADediting_292204	chr11_94417171_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-3188	chr11	94417167	94417173	7mer-m8	94417166	94417188	143	-15.93
ADediting_292204	chr11_94417171_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-412-3p	chr11	94417171	94417177	7mer-m8	94417170	94417192	153	-17.3
ADediting_292204	chr11_94417171_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6754-3p	chr11	94417171	94417177	7mer-m8	94417170	94417190	144	-15.76
ADediting_292205	chr11_94417172_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-1229-3p	chr11	94417171	94417177	7mer-m8	94417170	94417194	146	-16.14
ADediting_292205	chr11_94417172_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6511a-3p	chr11	94417171	94417178	8mer-1a	94417171	94417192	145	-15.78
ADediting_292205	chr11_94417172_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6511b-3p	chr11	94417171	94417178	8mer-1a	94417171	94417193	140	-14.97
ADediting_292207	chr11_94417181_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-3190-5p	chr11	94417181	94417187	7mer-m8	94417180	94417199	154	-19.64
ADediting_292211	chr11_94417202_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4732-3p	chr11	94417202	94417208	7mer-m8	94417201	94417221	150	-20.45
ADediting_292211	chr11_94417202_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6771-3p	chr11	94417198	94417204	7mer-m8	94417197	94417217	155	-26.23
ADediting_292213	chr11_94417210_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4726-3p	chr11	94417209	94417215	7mer-m8	94417208	94417235	153	-34.11
ADediting_292214	chr11_94417227_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4707-5p	chr11	94417224	94417231	8mer-1a	94417224	94417246	142	-26.89
ADediting_292214	chr11_94417227_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6763-3p	chr11	94417224	94417230	7mer-m8	94417223	94417243	161	-34.85
ADediting_292215	chr11_94417241_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-518a-3p	chr11	94417237	94417243	7mer-m8	94417236	94417257	145	-14.14
ADediting_292215	chr11_94417241_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-518b	chr11	94417237	94417243	7mer-m8	94417236	94417256	150	-23.6
ADediting_292215	chr11_94417241_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-518c-3p	chr11	94417237	94417243	7mer-m8	94417236	94417257	150	-19.89
ADediting_292215	chr11_94417241_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-518d-3p	chr11	94417237	94417243	7mer-m8	94417236	94417256	145	-18.89
ADediting_292215	chr11_94417241_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-518e-3p	chr11	94417238	94417244	7mer-m8	94417237	94417256	145	-12.74
ADediting_292215	chr11_94417241_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-518f-3p	chr11	94417237	94417243	7mer-m8	94417236	94417256	146	-19.29
ADediting_292215	chr11_94417241_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-526a-3p	chr11	94417237	94417243	7mer-m8	94417236	94417256	150	-19.52
ADediting_292216	chr11_94417244_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-371a-3p	chr11	94417239	94417245	7mer-m8	94417238	94417260	144	-14.89
ADediting_292217	chr11_94417249_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4509	chr11	94417249	94417255	7mer-m8	94417248	94417269	143	-12.11
ADediting_292217	chr11_94417249_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-8052	chr11	94417244	94417250	7mer-1a	94417244	94417262	148	-29.66
ADediting_292218	chr11_94417250_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-638	chr11	94417244	94417250	7mer-1a	94417244	94417270	146	-25.66
ADediting_292219	chr11_94417258_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-3622a-5p	chr11	94417253	94417259	7mer-m8	94417252	94417273	146	-20.33
ADediting_292221	chr11_94417279_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-181a-2-3p	chr11	94417276	94417282	7mer-m8	94417275	94417293	142	-12.46
ADediting_292223	chr11_94417289_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-130a-5p	chr11	94417287	94417293	7mer-m8	94417286	94417311	150	-10.29
ADediting_292224	chr11_94418564_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-2682-5p	chr11	94418560	94418566	7mer-1a	94418560	94418586	140	-22.94
ADediting_292224	chr11_94418564_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6806-5p	chr11	94418559	94418565	7mer-m8	94418558	94418582	153	-23.06

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

ADeditom_ID	Position	ENSG	ENST	Transcript name	miRNA ID	Chromosome	Targt	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
ADediting_1529403	chr11_94415932_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-1200	chr11	94415932	94415938	7mer-m8	94415931	94415952	145	-16.48
ADediting_1529403	chr11_94415932_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6791-3p	chr11	94415929	94415935	7mer-m8	94415928	94415948	148	-16.86
ADediting_1529403	chr11_94415932_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6829-3p	chr11	94415929	94415935	7mer-m8	94415928	94415947	150	-18.68
ADediting_1529404	chr11_94416005_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-193b-5p	chr11	94416000	94416006	7mer-m8	94415999	94416020	146	-23.38
ADediting_1529406	chr11_94417160_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6832-5p	chr11	94417159	94417165	7mer-m8	94417158	94417180	147	-14.92
ADediting_292134	chr11_94415841_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-431-5p	chr11	94415837	94415843	7mer-m8	94415836	94415856	140	-13.39
ADediting_292134	chr11_94415841_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-5691	chr11	94415840	94415847	8mer-1a	94415840	94415862	146	-19.21
ADediting_292135	chr11_94415844_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-3194-3p	chr11	94415841	94415847	7mer-1a	94415841	94415864	141	-26.5
ADediting_292135	chr11_94415844_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-5691	chr11	94415840	94415847	8mer-1a	94415840	94415862	146	-19.21
ADediting_292137	chr11_94415876_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-144-5p	chr11	94415873	94415880	8mer-1a	94415873	94415892	151	-14.06
ADediting_292139	chr11_94415922_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-1976	chr11	94415917	94415924	8mer-1a	94415917	94415937	153	-25.04
ADediting_292139	chr11_94415922_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6747-3p	chr11	94415919	94415926	8mer-1a	94415919	94415941	149	-23.42
ADediting_292140	chr11_94415935_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-1200	chr11	94415932	94415938	7mer-m8	94415931	94415952	145	-16.48
ADediting_292140	chr11_94415935_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6869-5p	chr11	94415935	94415941	7mer-m8	94415934	94415958	150	-22.74
ADediting_292141	chr11_94415939_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4703-3p	chr11	94415938	94415944	7mer-m8	94415937	94415960	154	-17.34
ADediting_292141	chr11_94415939_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6869-5p	chr11	94415935	94415941	7mer-m8	94415934	94415958	150	-22.74
ADediting_292142	chr11_94415942_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4259	chr11	94415939	94415946	8mer-1a	94415939	94415960	153	-21.78
ADediting_292142	chr11_94415942_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4703-3p	chr11	94415938	94415944	7mer-m8	94415937	94415960	154	-17.34
ADediting_292142	chr11_94415942_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6513-5p	chr11	94415942	94415948	7mer-m8	94415941	94415965	153	-21.98
ADediting_292143	chr11_94415943_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4259	chr11	94415939	94415946	8mer-1a	94415939	94415960	153	-21.78
ADediting_292143	chr11_94415943_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4703-3p	chr11	94415938	94415944	7mer-m8	94415937	94415960	154	-17.34
ADediting_292143	chr11_94415943_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-5089-5p	chr11	94415942	94415949	8mer-1a	94415942	94415962	144	-13.84
ADediting_292143	chr11_94415943_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6513-5p	chr11	94415942	94415948	7mer-m8	94415941	94415965	153	-21.98
ADediting_292144	chr11_94415948_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-10399-5p	chr11	94415947	94415953	7mer-m8	94415946	94415965	141	-11.84
ADediting_292144	chr11_94415948_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-5089-5p	chr11	94415942	94415949	8mer-1a	94415942	94415962	144	-13.84
ADediting_292144	chr11_94415948_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6504-3p	chr11	94415947	94415953	7mer-m8	94415946	94415970	148	-14.06
ADediting_292145	chr11_94415949_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-10399-5p	chr11	94415947	94415953	7mer-m8	94415946	94415965	141	-11.84
ADediting_292145	chr11_94415949_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6504-3p	chr11	94415947	94415953	7mer-m8	94415946	94415970	148	-14.06
ADediting_292145	chr11_94415949_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-7151-3p	chr11	94415948	94415955	8mer-1a	94415948	94415968	140	-13.39
ADediting_292146	chr11_94415967_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6872-3p	chr11	94415964	94415970	7mer-m8	94415963	94415983	145	-14.21
ADediting_292147	chr11_94415971_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4794	chr11	94415970	94415976	7mer-m8	94415969	94415990	140	-12.3
ADediting_292147	chr11_94415971_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-664a-5p	chr11	94415970	94415976	7mer-m8	94415969	94415992	141	-13.02
ADediting_292148	chr11_94415975_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4735-5p	chr11	94415974	94415980	7mer-m8	94415973	94415994	140	-5.48
ADediting_292148	chr11_94415975_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4794	chr11	94415970	94415976	7mer-m8	94415969	94415990	140	-12.3
ADediting_292148	chr11_94415975_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-664a-5p	chr11	94415970	94415976	7mer-m8	94415969	94415992	141	-13.02
ADediting_292150	chr11_94416004_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-193b-5p	chr11	94416000	94416006	7mer-m8	94415999	94416020	146	-23.38
ADediting_292151	chr11_94416014_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4716-5p	chr11	94416009	94416015	7mer-m8	94416008	94416030	146	-14.29
ADediting_292151	chr11_94416014_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4781-3p	chr11	94416011	94416017	7mer-m8	94416010	94416028	151	-17.38
ADediting_292152	chr11_94416015_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-328-3p	chr11	94416014	94416021	8mer-1a	94416014	94416034	148	-18.15
ADediting_292152	chr11_94416015_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4781-3p	chr11	94416011	94416017	7mer-m8	94416010	94416028	151	-17.38
ADediting_292153	chr11_94416024_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-3663-5p	chr11	94416023	94416029	7mer-m8	94416022	94416041	148	-21.98
ADediting_292153	chr11_94416024_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6131	chr11	94416021	94416028	8mer-1a	94416021	94416039	140	-15.32
ADediting_292153	chr11_94416024_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6843-3p	chr11	94416024	94416030	7mer-m8	94416023	94416042	152	-19.47
ADediting_292153	chr11_94416024_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6848-3p	chr11	94416024	94416030	7mer-m8	94416023	94416040	142	-14.3
ADediting_292153	chr11_94416024_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6893-3p	chr11	94416019	94416025	7mer-m8	94416018	94416040	150	-24.63
ADediting_292155	chr11_94416057_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4485-5p	chr11	94416051	94416058	8mer-1a	94416051	94416066	145	-17.76
ADediting_292157	chr11_94416062_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6878-3p	chr11	94416061	94416068	8mer-1a	94416061	94416081	142	-17.1
ADediting_292158	chr11_94416075_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-302a-3p	chr11	94416072	94416078	7mer-m8	94416071	94416093	141	-15.53
ADediting_292158	chr11_94416075_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-302b-3p	chr11	94416072	94416078	7mer-m8	94416071	94416098	143	-15.61
ADediting_292158	chr11_94416075_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-302c-3p	chr11	94416072	94416078	7mer-m8	94416071	94416098	143	-18.95
ADediting_292158	chr11_94416075_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-302d-3p	chr11	94416072	94416078	7mer-m8	94416071	94416098	151	-16.54
ADediting_292158	chr11_94416075_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-302e	chr11	94416072	94416078	7mer-m8	94416071	94416087	141	-8.86
ADediting_292158	chr11_94416075_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-372-3p	chr11	94416072	94416078	7mer-m8	94416071	94416094	151	-20.59
ADediting_292158	chr11_94416075_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-519d-3p	chr11	94416071	94416077	7mer-m8	94416070	94416090	142	-14.43
ADediting_292158	chr11_94416075_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-520a-3p	chr11	94416072	94416078	7mer-m8	94416071	94416092	140	-11.73
ADediting_292158	chr11_94416075_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-520b-3p	chr11	94416072	94416078	7mer-m8	94416071	94416091	140	-17.12
ADediting_292158	chr11_94416075_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-520c-3p	chr11	94416072	94416078	7mer-m8	94416071	94416091	142	-17.12
ADediting_292158	chr11_94416075_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-520d-3p	chr11	94416072	94416078	7mer-m8	94416071	94416094	142	-17.31
ADediting_292158	chr11_94416075_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-520e-3p	chr11	94416072	94416078	7mer-m8	94416071	94416091	140	-13.45
ADediting_292158	chr11_94416075_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-520g-3p	chr11	94416070	94416076	7mer-m8	94416069	94416092	150	-19.33
ADediting_292158	chr11_94416075_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-520h	chr11	94416070	94416076	7mer-m8	94416069	94416090	150	-15.68
ADediting_292158	chr11_94416075_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-526b-3p	chr11	94416071	94416077	7mer-m8	94416070	94416091	145	-17.71
ADediting_292159	chr11_94416092_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6807-5p	chr11	94416092	94416098	7mer-m8	94416091	94416113	146	-25.49
ADediting_292161	chr11_94416580_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-24-3p	chr11	94416576	94416583	8mer-1a	94416576	94416597	148	-19.46
ADediting_292161	chr11_94416580_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-3934-3p	chr11	94416578	94416584	7mer-m8	94416577	94416599	147	-18.4
ADediting_292164	chr11_94416602_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-887-5p	chr11	94416601	94416608	8mer-1a	94416601	94416620	143	-13.53
ADediting_292165	chr11_94416603_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-1273h-5p	chr11	94416602	94416609	8mer-1a	94416602	94416621	151	-19.49
ADediting_292165	chr11_94416603_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-30b-3p	chr11	94416602	94416609	8mer-1a	94416602	94416623	155	-16.01
ADediting_292165	chr11_94416603_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-3689a-3p	chr11	94416602	94416609	8mer-1a	94416602	94416623	149	-22.05
ADediting_292165	chr11_94416603_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-3689b-3p	chr11	94416602	94416609	8mer-1a	94416602	94416623	149	-22.1
ADediting_292165	chr11_94416603_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-3689c	chr11	94416602	94416609	8mer-1a	94416602	94416623	149	-22.1
ADediting_292165	chr11_94416603_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6779-5p	chr11	94416602	94416609	8mer-1a	94416602	94416620	152	-22.88
ADediting_292165	chr11_94416603_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6780a-5p	chr11	94416602	94416609	8mer-1a	94416602	94416625	148	-20.23
ADediting_292165	chr11_94416603_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-887-5p	chr11	94416601	94416608	8mer-1a	94416601	94416620	143	-13.53
ADediting_292166	chr11_94416611_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4478	chr11	94416607	94416613	7mer-m8	94416606	94416622	154	-23.41
ADediting_292166	chr11_94416611_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-485-5p	chr11	94416606	94416612	7mer-m8	94416605	94416626	149	-16.76
ADediting_292166	chr11_94416611_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-7160-5p	chr11	94416609	94416615	7mer-m8	94416608	94416625	148	-19.34
ADediting_292166	chr11_94416611_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-7162-3p	chr11	94416610	94416616	7mer-m8	94416609	94416627	150	-18.37
ADediting_292167	chr11_94416616_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6134	chr11	94416611	94416618	8mer-1a	94416611	94416629	154	-20.33
ADediting_292167	chr11_94416616_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6769a-5p	chr11	94416614	94416620	7mer-m8	94416613	94416631	142	-18.71
ADediting_292167	chr11_94416616_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6769b-5p	chr11	94416614	94416620	7mer-m8	94416613	94416633	153	-25.54
ADediting_292168	chr11_94416620_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6756-5p	chr11	94416616	94416622	7mer-1a	94416616	94416638	149	-26.59
ADediting_292169	chr11_94416624_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-513b-5p	chr11	94416624	94416630	7mer-m8	94416623	94416647	150	-16.23
ADediting_292170	chr11_94416632_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-3974	chr11	94416628	94416634	7mer-m8	94416627	94416649	140	-12.12
ADediting_292171	chr11_94416652_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-664a-5p	chr11	94416651	94416657	7mer-m8	94416650	94416676	152	-19.41
ADediting_292172	chr11_94416656_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-664a-5p	chr11	94416651	94416657	7mer-m8	94416650	94416676	152	-19.41
ADediting_292173	chr11_94416672_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-10a-5p	chr11	94416668	94416674	7mer-m8	94416667	94416689	145	-13.67
ADediting_292173	chr11_94416672_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-10b-5p	chr11	94416668	94416674	7mer-m8	94416667	94416689	140	-13.05
ADediting_292173	chr11_94416672_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-339-5p	chr11	94416669	94416675	7mer-m8	94416668	94416692	151	-18.58
ADediting_292173	chr11_94416672_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4421	chr11	94416670	94416676	7mer-m8	94416669	94416690	154	-16.19
ADediting_292173	chr11_94416672_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-5699-3p	chr11	94416670	94416676	7mer-m8	94416669	94416690	153	-17.34
ADediting_292173	chr11_94416672_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6818-3p	chr11	94416672	94416678	7mer-m8	94416671	94416692	140	-12.56
ADediting_292174	chr11_94416678_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-593-3p	chr11	94416672	94416678	7mer-1a	94416672	94416690	140	-19.02
ADediting_292177	chr11_94416734_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6720-3p	chr11	94416729	94416735	7mer-m8	94416728	94416749	152	-20.67
ADediting_292179	chr11_94416746_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-5690	chr11	94416742	94416748	7mer-m8	94416741	94416761	145	-16.74
ADediting_292180	chr11_94416749_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-12126	chr11	94416746	94416753	8mer-1a	94416746	94416769	147	-13.23
ADediting_292180	chr11_94416749_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-887-5p	chr11	94416749	94416755	7mer-m8	94416748	94416767	143	-19.73
ADediting_292181	chr11_94416750_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-12126	chr11	94416746	94416753	8mer-1a	94416746	94416769	147	-13.23
ADediting_292181	chr11_94416750_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-30b-3p	chr11	94416749	94416756	8mer-1a	94416749	94416770	151	-15.38
ADediting_292181	chr11_94416750_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-3689a-3p	chr11	94416749	94416756	8mer-1a	94416749	94416769	147	-18.72
ADediting_292181	chr11_94416750_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-3689b-3p	chr11	94416749	94416756	8mer-1a	94416749	94416769	147	-17.55
ADediting_292181	chr11_94416750_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-3689c	chr11	94416749	94416756	8mer-1a	94416749	94416769	147	-17.55
ADediting_292181	chr11_94416750_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6779-5p	chr11	94416749	94416756	8mer-1a	94416749	94416767	148	-22.58
ADediting_292181	chr11_94416750_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6780a-5p	chr11	94416749	94416756	8mer-1a	94416749	94416772	152	-25.37
ADediting_292181	chr11_94416750_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-887-5p	chr11	94416749	94416755	7mer-m8	94416748	94416767	143	-19.73
ADediting_292182	chr11_94416758_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4478	chr11	94416754	94416760	7mer-m8	94416753	94416768	149	-25.05
ADediting_292182	chr11_94416758_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4649-3p	chr11	94416757	94416763	7mer-m8	94416756	94416776	140	-14.11
ADediting_292182	chr11_94416758_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-7160-5p	chr11	94416756	94416762	7mer-m8	94416755	94416774	149	-18.69
ADediting_292185	chr11_94416807_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-18a-3p	chr11	94416806	94416812	7mer-m8	94416805	94416827	140	-20.7
ADediting_292185	chr11_94416807_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6752-3p	chr11	94416804	94416810	7mer-m8	94416803	94416824	155	-25.77
ADediting_292185	chr11_94416807_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6810-3p	chr11	94416803	94416809	7mer-m8	94416802	94416824	153	-23.38
ADediting_292186	chr11_94416812_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4290	chr11	94416807	94416814	8mer-1a	94416807	94416825	145	-19.86
ADediting_292186	chr11_94416812_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6512-3p	chr11	94416812	94416818	7mer-m8	94416811	94416832	147	-19.3
ADediting_292186	chr11_94416812_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-766-3p	chr11	94416811	94416817	7mer-m8	94416810	94416831	145	-16.97
ADediting_292189	chr11_94417005_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6794-3p	chr11	94417004	94417011	8mer-1a	94417004	94417023	144	-13.38
ADediting_292190	chr11_94417009_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6794-3p	chr11	94417004	94417011	8mer-1a	94417004	94417023	144	-13.38
ADediting_292191	chr11_94417044_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4638-5p	chr11	94417042	94417049	8mer-1a	94417042	94417061	146	-20.28
ADediting_292193	chr11_94417088_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-1976	chr11	94417083	94417090	8mer-1a	94417083	94417103	153	-25.04
ADediting_292193	chr11_94417088_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6747-3p	chr11	94417085	94417092	8mer-1a	94417085	94417107	149	-23.42
ADediting_292194	chr11_94417101_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-1200	chr11	94417098	94417104	7mer-m8	94417097	94417116	142	-20.58
ADediting_292194	chr11_94417101_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6869-5p	chr11	94417101	94417107	7mer-m8	94417100	94417121	141	-14.76
ADediting_292195	chr11_94417105_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6869-5p	chr11	94417101	94417107	7mer-m8	94417100	94417121	141	-14.76
ADediting_292197	chr11_94417114_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-10399-5p	chr11	94417113	94417119	7mer-m8	94417112	94417132	140	-7.83
ADediting_292198	chr11_94417115_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-10399-5p	chr11	94417113	94417119	7mer-m8	94417112	94417132	140	-7.83
ADediting_292198	chr11_94417115_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-7151-3p	chr11	94417114	94417121	8mer-1a	94417114	94417134	140	-11.08
ADediting_292199	chr11_94417133_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6872-3p	chr11	94417130	94417136	7mer-m8	94417129	94417149	141	-14.75
ADediting_292207	chr11_94417181_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4716-5p	chr11	94417176	94417182	7mer-m8	94417175	94417196	140	-11.3
ADediting_292207	chr11_94417181_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4781-3p	chr11	94417178	94417184	7mer-m8	94417177	94417195	144	-13.86
ADediting_292208	chr11_94417182_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4435	chr11	94417181	94417188	8mer-1a	94417181	94417202	149	-18.63
ADediting_292208	chr11_94417182_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-4781-3p	chr11	94417178	94417184	7mer-m8	94417177	94417195	144	-13.86
ADediting_292209	chr11_94417191_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-3663-5p	chr11	94417190	94417196	7mer-m8	94417189	94417208	144	-20.26
ADediting_292209	chr11_94417191_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6131	chr11	94417189	94417195	7mer-m8	94417188	94417206	140	-16.72
ADediting_292209	chr11_94417191_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6843-3p	chr11	94417191	94417197	7mer-m8	94417190	94417209	152	-20.48
ADediting_292209	chr11_94417191_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6848-3p	chr11	94417191	94417197	7mer-m8	94417190	94417207	142	-15.32
ADediting_292210	chr11_94417196_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-371a-5p	chr11	94417194	94417201	8mer-1a	94417194	94417213	146	-15.86
ADediting_292210	chr11_94417196_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6843-3p	chr11	94417191	94417197	7mer-m8	94417190	94417209	152	-20.48
ADediting_292210	chr11_94417196_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6848-3p	chr11	94417191	94417197	7mer-m8	94417190	94417207	142	-15.32
ADediting_292213	chr11_94417210_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6790-3p	chr11	94417205	94417211	7mer-1a	94417205	94417226	145	-28.27
ADediting_292214	chr11_94417227_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-5193	chr11	94417222	94417228	7mer-m8	94417221	94417242	154	-26.07
ADediting_292215	chr11_94417241_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-302a-3p	chr11	94417238	94417244	7mer-m8	94417237	94417259	141	-11.02
ADediting_292215	chr11_94417241_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-302b-3p	chr11	94417238	94417244	7mer-m8	94417237	94417259	141	-9.21
ADediting_292215	chr11_94417241_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-302c-3p	chr11	94417238	94417244	7mer-m8	94417237	94417259	141	-11.96
ADediting_292215	chr11_94417241_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-302d-3p	chr11	94417238	94417244	7mer-m8	94417237	94417259	141	-9.98
ADediting_292215	chr11_94417241_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-302e	chr11	94417238	94417244	7mer-m8	94417237	94417253	141	-8.62
ADediting_292215	chr11_94417241_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-512-3p	chr11	94417239	94417245	7mer-m8	94417238	94417257	145	-15.63
ADediting_292215	chr11_94417241_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-519d-3p	chr11	94417237	94417243	7mer-m8	94417236	94417256	150	-16.34
ADediting_292215	chr11_94417241_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-520a-3p	chr11	94417238	94417244	7mer-m8	94417237	94417258	140	-11.03
ADediting_292215	chr11_94417241_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-520b-3p	chr11	94417238	94417244	7mer-m8	94417237	94417256	145	-18.33
ADediting_292215	chr11_94417241_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-520c-3p	chr11	94417238	94417244	7mer-m8	94417237	94417257	150	-18.33
ADediting_292215	chr11_94417241_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-520d-3p	chr11	94417238	94417244	7mer-m8	94417237	94417258	140	-13.94
ADediting_292215	chr11_94417241_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-520e-3p	chr11	94417238	94417244	7mer-m8	94417237	94417257	140	-16.96
ADediting_292215	chr11_94417241_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-520g-3p	chr11	94417236	94417242	7mer-m8	94417235	94417257	155	-17.68
ADediting_292215	chr11_94417241_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-520h	chr11	94417236	94417242	7mer-m8	94417235	94417256	151	-16.89
ADediting_292215	chr11_94417241_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-526b-3p	chr11	94417237	94417243	7mer-m8	94417236	94417256	150	-18.47
ADediting_292216	chr11_94417244_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-5089-5p	chr11	94417244	94417250	7mer-m8	94417243	94417263	140	-13.6
ADediting_292216	chr11_94417244_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-512-3p	chr11	94417239	94417245	7mer-m8	94417238	94417257	145	-15.63
ADediting_292216	chr11_94417244_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6506-5p	chr11	94417243	94417249	7mer-m8	94417242	94417263	144	-14.41
ADediting_292217	chr11_94417249_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-5089-5p	chr11	94417244	94417250	7mer-m8	94417243	94417263	140	-13.6
ADediting_292219	chr11_94417258_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-6807-5p	chr11	94417258	94417264	7mer-m8	94417257	94417278	149	-17.97
ADediting_292220	chr11_94417266_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-3130-3p	chr11	94417265	94417271	7mer-m8	94417264	94417283	142	-16.88
ADediting_292224	chr11_94418564_-	ENSG00000020922.12	ENST00000323929.7	MRE11-201	hsa-miR-585-5p	chr11	94418564	94418570	7mer-m8	94418563	94418586	146	-19.33

RNA A-to-I editing in lncRNA gained miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

ADediting_1391023

chr8_140732605_-

ENSG00000020922.12

ENST00000323929.7

MRE11-201

hsa-miR-151a-3p

chr11

94416481

94416488

8mer-1a

94416481

94416501

159

-19

ADediting_1535951

chr14_100874558_+

ENSG00000020922.12

ENST00000323929.7

MRE11-201

hsa-miR-337-3p

chr11

94420086

94420093

8mer-1a

94420086

94420109

163

-17.71

ADediting_1535951

chr14_100874558_+

ENSG00000020922.12

ENST00000323977.7

MRE11-202

hsa-miR-337-3p

chr11

94420086

94420093

8mer-1a

94420086

94420109

163

-17.71

ADediting_1535951

chr14_100874558_+

ENSG00000020922.12

ENST00000393241.8

MRE11-203

hsa-miR-337-3p

chr11

94420086

94420093

8mer-1a

94420086

94420109

163

-17.71

ADediting_1535951

chr14_100874558_+

ENSG00000020922.12

ENST00000407439.7

MRE11-204

hsa-miR-337-3p

chr11

94420086

94420093

8mer-1a

94420086

94420109

163

-17.71

ADediting_1631458

chr19_40282624_-

ENSG00000020922.12

ENST00000323929.7

MRE11-201

hsa-miR-641

chr11

94416905

94416911

7mer-m8

94416904

94416927

153

-16.21

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

ADediting_1097295

chr3_85385762_+

ENSG00000020922.12

ENST00000323929.7

MRE11-201

hsa-miR-5688

chr11

94419703

94419710

8mer-1a

94419703

94419724

145

-11.14

ADediting_1471003

chr9_63819626_+

ENSG00000020922.12

ENST00000323929.7

MRE11-201

hsa-miR-4477b

chr11

94418161

94418167

7mer-m8

94418160

94418183

153

-9.88

ADediting_1471003

chr9_63819626_+

ENSG00000020922.12

ENST00000323929.7

MRE11-201

hsa-miR-4477b

chr11

94418392

94418399

8mer-1a

94418392

94418413

142

-6.62

ADediting_1471003

chr9_63819626_+

ENSG00000020922.12

ENST00000323929.7

MRE11-201

hsa-miR-4477b

chr11

94419502

94419508

7mer-m8

94419501

94419523

145

-10.28

ADediting_1471004

chr9_63819627_+

ENSG00000020922.12

ENST00000323929.7

MRE11-201

hsa-miR-4477b

chr11

94418161

94418167

7mer-m8

94418160

94418183

153

-9.88

ADediting_1471004

chr9_63819627_+

ENSG00000020922.12

ENST00000323929.7

MRE11-201

hsa-miR-4477b

chr11

94418392

94418399

8mer-1a

94418392

94418413

142

-6.62

ADediting_1471004

chr9_63819627_+

ENSG00000020922.12

ENST00000323929.7

MRE11-201

hsa-miR-4477b

chr11

94419502

94419508

7mer-m8

94419501

94419523

145

-10.28

ADediting_1535951

chr14_100874558_+

ENSG00000020922.12

ENST00000323929.7

MRE11-201

hsa-miR-337-3p

chr11

94418073

94418080

8mer-1a

94418073

94418093

146

-9.92

ADediting_1556067

chr19_40282625_-

ENSG00000020922.12

ENST00000323929.7

MRE11-201

hsa-miR-641

chr11

94416314

94416320

7mer-m8

94416313

94416336

148

-11.35

ADediting_1631458

chr19_40282624_-

ENSG00000020922.12

ENST00000323929.7

MRE11-201

hsa-miR-641

chr11

94416314

94416320

7mer-m8

94416313

94416336

148

-11.35

Differentially expressed gene-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for MRE11

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000323929.7	protein_coding

RNA A-to-I editing in miRNA.

ADeditom_ID

ENST

mir_ID

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

RNA A-to-I editing in mRNA.

ADeditom_ID	ENST	Editing_Information	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
ADediting_292134	ENST00000323929.7	chr11_94415841_-	6634	-2022.40	-2021.10	-2101.40
ADediting_292135	ENST00000323929.7	chr11_94415844_-	6631	-2020.40	-2021.10	-2101.40
ADediting_292136	ENST00000323929.7	chr11_94415873_-	6602	-2026.30	-2021.10	-2101.40
ADediting_292137	ENST00000323929.7	chr11_94415876_-	6599	-2026.90	-2021.10	-2101.40
ADediting_292138	ENST00000323929.7	chr11_94415889_-	6586	-2024.60	-2021.10	-2101.40
ADediting_292139	ENST00000323929.7	chr11_94415922_-	6553	-2022.10	-2021.10	-2101.40
ADediting_1529402	ENST00000323929.7	chr11_94415926_-	6549	-2021.80	-2021.10	-2101.40
ADediting_1529403	ENST00000323929.7	chr11_94415932_-	6543	-2025.80	-2021.10	-2101.40
ADediting_292140	ENST00000323929.7	chr11_94415935_-	6540	-2023.70	-2021.10	-2101.40
ADediting_292141	ENST00000323929.7	chr11_94415939_-	6536	-2022.50	-2021.10	-2101.40
ADediting_292142	ENST00000323929.7	chr11_94415942_-	6533	-2022.40	-2021.10	-2101.40
ADediting_292143	ENST00000323929.7	chr11_94415943_-	6532	-2021.20	-2021.10	-2101.40
ADediting_292144	ENST00000323929.7	chr11_94415948_-	6527	-2023.20	-2021.10	-2101.40
ADediting_292145	ENST00000323929.7	chr11_94415949_-	6526	-2027.50	-2021.10	-2101.40
ADediting_292146	ENST00000323929.7	chr11_94415967_-	6508	-2026.20	-2021.10	-2101.40
ADediting_292147	ENST00000323929.7	chr11_94415971_-	6504	-2023.70	-2021.10	-2101.40
ADediting_292148	ENST00000323929.7	chr11_94415975_-	6500	-2023.00	-2021.10	-2101.40
ADediting_1611359	ENST00000323929.7	chr11_94415984_-	6491	-2021.50	-2021.10	-2101.40
ADediting_292149	ENST00000323929.7	chr11_94415990_-	6485	-2021.50	-2021.10	-2101.40
ADediting_292150	ENST00000323929.7	chr11_94416004_-	6471	-2021.70	-2021.10	-2101.40
ADediting_1529404	ENST00000323929.7	chr11_94416005_-	6470	-2024.60	-2021.10	-2101.40
ADediting_292151	ENST00000323929.7	chr11_94416014_-	6461	-2021.40	-2021.10	-2101.40
ADediting_292152	ENST00000323929.7	chr11_94416015_-	6460	-2020.50	-2021.10	-2101.40
ADediting_292153	ENST00000323929.7	chr11_94416024_-	6451	-2020.40	-2021.10	-2101.40
ADediting_292154	ENST00000323929.7	chr11_94416038_-	6437	-2022.90	-2021.10	-2101.40
ADediting_292155	ENST00000323929.7	chr11_94416057_-	6418	-2022.20	-2021.10	-2101.40
ADediting_292156	ENST00000323929.7	chr11_94416060_-	6415	-2020.80	-2021.10	-2101.40
ADediting_292157	ENST00000323929.7	chr11_94416062_-	6413	-2020.80	-2021.10	-2101.40
ADediting_292158	ENST00000323929.7	chr11_94416075_-	6400	-2024.00	-2021.10	-2101.40
ADediting_292159	ENST00000323929.7	chr11_94416092_-	6383	-2021.30	-2021.10	-2101.40
ADediting_292160	ENST00000323929.7	chr11_94416573_-	5902	-2025.00	-2021.10	-2101.40
ADediting_292161	ENST00000323929.7	chr11_94416580_-	5895	-2020.20	-2021.10	-2101.40
ADediting_292162	ENST00000323929.7	chr11_94416589_-	5886	-2020.80	-2021.10	-2101.40
ADediting_292163	ENST00000323929.7	chr11_94416601_-	5874	-2020.80	-2021.10	-2101.40
ADediting_292164	ENST00000323929.7	chr11_94416602_-	5873	-2021.20	-2021.10	-2101.40
ADediting_292165	ENST00000323929.7	chr11_94416603_-	5872	-2020.80	-2021.10	-2101.40
ADediting_292166	ENST00000323929.7	chr11_94416611_-	5864	-2027.30	-2021.10	-2101.40
ADediting_292167	ENST00000323929.7	chr11_94416616_-	5859	-2022.10	-2021.10	-2101.40
ADediting_292168	ENST00000323929.7	chr11_94416620_-	5855	-2021.10	-2021.10	-2101.40
ADediting_292169	ENST00000323929.7	chr11_94416624_-	5851	-2019.50	-2021.10	-2101.40
ADediting_292170	ENST00000323929.7	chr11_94416632_-	5843	-2020.50	-2021.10	-2101.40
ADediting_292171	ENST00000323929.7	chr11_94416652_-	5823	-2020.40	-2021.10	-2101.40
ADediting_292172	ENST00000323929.7	chr11_94416656_-	5819	-2027.70	-2021.10	-2101.40
ADediting_292173	ENST00000323929.7	chr11_94416672_-	5803	-2026.30	-2021.10	-2101.40
ADediting_292174	ENST00000323929.7	chr11_94416678_-	5797	-2020.80	-2021.10	-2101.40
ADediting_292175	ENST00000323929.7	chr11_94416681_-	5794	-2020.80	-2021.10	-2101.40
ADediting_292176	ENST00000323929.7	chr11_94416687_-	5788	-2021.10	-2021.10	-2101.40
ADediting_1611360	ENST00000323929.7	chr11_94416723_-	5752	-2020.70	-2021.10	-2101.40
ADediting_292177	ENST00000323929.7	chr11_94416734_-	5741	-2020.40	-2021.10	-2101.40
ADediting_292178	ENST00000323929.7	chr11_94416736_-	5739	-2021.10	-2021.10	-2101.40
ADediting_292179	ENST00000323929.7	chr11_94416746_-	5729	-2020.80	-2021.10	-2101.40
ADediting_292180	ENST00000323929.7	chr11_94416749_-	5726	-2020.70	-2021.10	-2101.40
ADediting_292181	ENST00000323929.7	chr11_94416750_-	5725	-2024.50	-2021.10	-2101.40
ADediting_292182	ENST00000323929.7	chr11_94416758_-	5717	-2020.40	-2021.10	-2101.40
ADediting_292183	ENST00000323929.7	chr11_94416798_-	5677	-2021.40	-2021.10	-2101.40
ADediting_292184	ENST00000323929.7	chr11_94416801_-	5674	-2020.70	-2021.10	-2101.40
ADediting_292185	ENST00000323929.7	chr11_94416807_-	5668	-2020.30	-2021.10	-2101.40
ADediting_292186	ENST00000323929.7	chr11_94416812_-	5663	-2021.10	-2021.10	-2101.40
ADediting_292187	ENST00000323929.7	chr11_94417003_-	5472	-2021.40	-2021.10	-2101.40
ADediting_292188	ENST00000323929.7	chr11_94417004_-	5471	-2026.70	-2021.10	-2101.40
ADediting_292189	ENST00000323929.7	chr11_94417005_-	5470	-2023.20	-2021.10	-2101.40
ADediting_292190	ENST00000323929.7	chr11_94417009_-	5466	-2020.70	-2021.10	-2101.40
ADediting_1529405	ENST00000323929.7	chr11_94417011_-	5464	-2022.20	-2021.10	-2101.40
ADediting_292191	ENST00000323929.7	chr11_94417044_-	5431	-2020.10	-2021.10	-2101.40
ADediting_292192	ENST00000323929.7	chr11_94417053_-	5422	-2020.40	-2021.10	-2101.40
ADediting_292193	ENST00000323929.7	chr11_94417088_-	5387	-2020.40	-2021.10	-2101.40
ADediting_292194	ENST00000323929.7	chr11_94417101_-	5374	-2024.70	-2021.10	-2101.40
ADediting_292195	ENST00000323929.7	chr11_94417105_-	5370	-2021.10	-2021.10	-2101.40
ADediting_292196	ENST00000323929.7	chr11_94417109_-	5366	-2019.80	-2021.10	-2101.40
ADediting_292197	ENST00000323929.7	chr11_94417114_-	5361	-2027.30	-2021.10	-2101.40
ADediting_292198	ENST00000323929.7	chr11_94417115_-	5360	-2020.80	-2021.10	-2101.40
ADediting_292199	ENST00000323929.7	chr11_94417133_-	5342	-2026.90	-2021.10	-2101.40
ADediting_292200	ENST00000323929.7	chr11_94417141_-	5334	-2020.80	-2021.10	-2101.40
ADediting_292201	ENST00000323929.7	chr11_94417146_-	5329	-2020.80	-2021.10	-2101.40
ADediting_292202	ENST00000323929.7	chr11_94417151_-	5324	-2021.10	-2021.10	-2101.40
ADediting_292203	ENST00000323929.7	chr11_94417155_-	5320	-2021.20	-2021.10	-2101.40
ADediting_1529406	ENST00000323929.7	chr11_94417160_-	5315	-2021.10	-2021.10	-2101.40
ADediting_292204	ENST00000323929.7	chr11_94417171_-	5304	-2021.10	-2021.10	-2101.40
ADediting_292205	ENST00000323929.7	chr11_94417172_-	5303	-2021.20	-2021.10	-2101.40
ADediting_292206	ENST00000323929.7	chr11_94417173_-	5302	-2020.70	-2021.10	-2101.40
ADediting_292207	ENST00000323929.7	chr11_94417181_-	5294	-2021.10	-2021.10	-2101.40
ADediting_292208	ENST00000323929.7	chr11_94417182_-	5293	-2021.50	-2021.10	-2101.40
ADediting_292209	ENST00000323929.7	chr11_94417191_-	5284	-2020.10	-2021.10	-2101.40
ADediting_292210	ENST00000323929.7	chr11_94417196_-	5279	-2020.20	-2021.10	-2101.40
ADediting_292211	ENST00000323929.7	chr11_94417202_-	5273	-2020.20	-2021.10	-2101.40
ADediting_292212	ENST00000323929.7	chr11_94417205_-	5270	-2020.40	-2021.10	-2101.40
ADediting_292213	ENST00000323929.7	chr11_94417210_-	5265	-2020.30	-2021.10	-2101.40
ADediting_292214	ENST00000323929.7	chr11_94417227_-	5248	-2020.20	-2021.10	-2101.40
ADediting_292215	ENST00000323929.7	chr11_94417241_-	5234	-2020.70	-2021.10	-2101.40
ADediting_292216	ENST00000323929.7	chr11_94417244_-	5231	-2020.40	-2021.10	-2101.40
ADediting_292217	ENST00000323929.7	chr11_94417249_-	5226	-2021.10	-2021.10	-2101.40
ADediting_292218	ENST00000323929.7	chr11_94417250_-	5225	-2021.20	-2021.10	-2101.40
ADediting_292219	ENST00000323929.7	chr11_94417258_-	5217	-2020.40	-2021.10	-2101.40
ADediting_292220	ENST00000323929.7	chr11_94417266_-	5209	-2025.80	-2021.10	-2101.40
ADediting_292221	ENST00000323929.7	chr11_94417279_-	5196	-2022.20	-2021.10	-2101.40
ADediting_292222	ENST00000323929.7	chr11_94417288_-	5187	-2021.10	-2021.10	-2101.40
ADediting_292223	ENST00000323929.7	chr11_94417289_-	5186	-2021.90	-2021.10	-2101.40
ADediting_292224	ENST00000323929.7	chr11_94418564_-	3911	-2023.80	-2021.10	-2101.40

RNA A-to-I editing in lncRNA.

ADeditom_ID

ENST

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for MRE11

Correlation between ADAR gene expression and RNA editing frequency

Tissue	ADeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
CER	ADediting_292140	chr11_94415935_-	0.0317076426562805	0.175494318102645	7.19254132769668e-07	0.39165447430176	0.0523794505723579	0.158722652123839
CER	ADediting_292141	chr11_94415939_-	0.0791341362951354	0.143811842836675	0.000155619962536355	0.303995303712999	0.372445520471514	0.0733388694288678
CER	ADediting_292142	chr11_94415942_-	0.00182051213138284	0.252560218468321	3.07573085095633e-08	0.433205786911992	0.22005869664345	0.100720584871601
CER	ADediting_292144	chr11_94415948_-	0.0926593685017377	0.137793601961402	4.58959793279537e-07	0.397931924145456	0.0773950052429371	0.144644441046063
CER	ADediting_292145	chr11_94415949_-	0.0573056357857989	0.155568794917587	0.000137390305250141	0.306358686634391	0.142788949396809	0.120227540440904
CER	ADediting_292150	chr11_94416004_-	0.000775633315896828	0.271548772919331	2.46888893828563e-09	0.46284861933745	0.00192335345983714	0.251287996027561
CER	ADediting_292151	chr11_94416014_-	0.012155136508263	0.204290283192795	6.66978274107158e-08	0.423509900093353	0.0209605376629522	0.188388962357172
CER	ADediting_292152	chr11_94416015_-	0.00156432791118286	0.256038903959623	2.01667660657695e-08	0.438367741527499	0.00278118207799005	0.242580324247075
CER	ADediting_292155	chr11_94416057_-	0.0283057980921612	0.179107292598304	6.90838405439733e-05	0.319053816604989	0.0575040162553184	0.155446542373458
CER	ADediting_292157	chr11_94416062_-	0.0173365870820832	0.194057323758233	1.49447282469291e-07	0.413069025064155	0.00216211033816253	0.248557575554071
DLPFC	ADediting_292160	chr11_94416573_-	1.04829218136452e-07	0.296432136381915	9.71835271400351e-11	0.356816054798461	0.716530761852688	0.0207040789730837
DLPFC	ADediting_292162	chr11_94416589_-	5.36380937620635e-06	0.255164788415461	2.09577136623787e-09	0.33187091526254	0.0105045638784392	0.145143899164499
CER	ADediting_292166	chr11_94416611_-	1.80559600042609e-05	0.342314131217855	0.000128744303552959	0.307583737491334	0.00286533811274229	0.241863151302592
DLPFC	ADediting_292172	chr11_94416656_-	0.0900899613493028	0.0964302747750835	0.734623905358122	0.0193291235600317	1.25223942645874e-14	0.419282199069469
DLPFC	ADediting_292178	chr11_94416736_-	4.98670384695145e-05	0.228253163036531	0.0119379043554444	0.142629624125522	5.61664137061084e-10	0.342837818583009
DLPFC	ADediting_292179	chr11_94416746_-	4.01287239582764e-08	0.305571661084646	3.23361197798928e-07	0.285288194374268	1.66509222979471e-07	0.291912069874062
DLPFC	ADediting_292184	chr11_94416801_-	5.63645968523143e-09	0.323336690364967	5.54060559957012e-10	0.342949124503147	0.000271831026315827	0.205402143013381
CER	ADediting_292184	chr11_94416801_-	5.58533158381118e-05	0.32286689667516	0.000320892791564076	0.289853673305729	0.497680474366712	0.0557938038353237
STG	ADediting_292184	chr11_94416801_-	0.0436776045224134	0.220676734716004	0.819709965979502	0.0252421604289723	0.00535170739159982	0.301294485916123
DLPFC	ADediting_292185	chr11_94416807_-	9.11137437061894e-07	0.274595240433369	1.04354546103565e-09	0.337731955935225	0.000220627870102344	0.208347932481224
DLPFC	ADediting_292186	chr11_94416812_-	2.31383308252641e-08	0.310674055232521	2.53648246176474e-08	0.309829397197991	0.000807621629502228	0.189318050492205
CER	ADediting_292186	chr11_94416812_-	5.06837849998052e-05	0.324592086631873	0.000648694611104193	0.275357829906932	0.576885049886071	-0.0459157156823092
DLPFC	ADediting_292188	chr11_94417004_-	4.62292513495142e-09	0.325067953415421	1.31274374618266e-06	0.270715360731523	0.000339952731633001	0.202199434005417
DLPFC	ADediting_292194	chr11_94417101_-	1.94392142195914e-08	0.31226835142936	2.01682097323318e-06	0.266074627961956	8.98138315717737e-07	0.274746692429239
DLPFC	ADediting_292195	chr11_94417105_-	2.80029646378345e-08	0.308916719113397	6.09017985139398e-06	0.253711644094561	7.86018777578603e-07	0.276147768439768
CER	ADediting_292197	chr11_94417114_-	1.89426752824347e-05	0.341514509316079	0.000206367459163934	0.298565942058171	0.0277646476050409	0.179715777848157
CER	ADediting_292198	chr11_94417115_-	2.19766088501032e-06	0.375460293738279	1.51414269786551e-05	0.345231711111431	0.104902825730718	0.132921600686563
CER	ADediting_292199	chr11_94417133_-	0.00177129586730596	0.253192352963768	9.64757427187257e-07	0.387479958313736	0.504440324790057	0.0549210261571051
DLPFC	ADediting_292200	chr11_94417141_-	5.29147436923432e-07	0.280260540849905	2.31130649230526e-08	0.310684083916287	0.00628157300645233	0.154895393586066
DLPFC	ADediting_292204	chr11_94417171_-	6.55057692739539e-08	0.300946872821821	5.54008649627733e-09	0.323487746016339	0.000189564692245435	0.210464497997423
DLPFC	ADediting_292207	chr11_94417181_-	1.92072112335959e-08	0.312377891304384	2.76884637687164e-10	0.348556637457989	0.000190582163985418	0.210390188781515
TCX	ADediting_292207	chr11_94417181_-	0.0346049384185092	0.172668204680864	0.4742920299817	0.0588631365564178	7.24648788893699e-05	0.318189726309579
DLPFC	ADediting_292208	chr11_94417182_-	6.11015238766114e-08	0.301608663786631	1.2350050083183e-09	0.336327305118291	7.63816762604979e-05	0.222727494824007
TCX	ADediting_292208	chr11_94417182_-	0.0126078479457521	0.20325744801004	0.337163310263038	0.0789039430585494	7.68393942344377e-06	0.356209869213285
DLPFC	ADediting_292209	chr11_94417191_-	1.05268629753962e-10	0.356193995577108	2.96188881529978e-14	0.413818004404748	0.0187717935284137	0.133414604984152
CER	ADediting_292209	chr11_94417191_-	0.00104322459836643	0.265108021590687	4.71494146869204e-05	0.325869352364592	0.427985538371124	0.0651955710435893
TCX	ADediting_292209	chr11_94417191_-	4.23407319140611e-05	0.327759672955831	2.24946043579803e-13	0.552699071895355	0.0329916357331988	-0.174215968413617
TCX	ADediting_292211	chr11_94417202_-	0.194210165376005	0.106589020017506	0.543570380024889	-0.0499829777731851	4.2908508134103e-06	0.365325074163854
DLPFC	ADediting_292212	chr11_94417205_-	9.61851907065214e-10	0.338409186895015	5.10977666531218e-11	0.361771657964564	0.00430313556233229	0.161739805338511
DLPFC	ADediting_292217	chr11_94417249_-	9.48957811561719e-08	0.297394511827007	2.08446549847866e-08	0.311630613425885	0.0572030252987634	0.108132420710156
DLPFC	ADediting_292218	chr11_94417250_-	1.11118000402049e-06	0.272493890365778	5.42913288383551e-09	0.323664837793133	0.116823477077448	0.089253162587716
DLPFC	ADediting_292220	chr11_94417266_-	3.41837114372274e-07	0.284725877783005	6.73567793602387e-10	0.341349925223154	0.152461848623441	0.0814630328766735
CER	ADediting_292220	chr11_94417266_-	0.000129879486565426	0.307418592715002	0.00226235599989313	0.24749208339718	0.122903783717484	0.126512526872733
DLPFC	ADediting_292222	chr11_94417288_-	6.19722522125689e-07	0.27862633729024	5.69814462208426e-08	0.302270791946636	0.468458243347585	0.0413260107421711

Correlation between ADAR gene expression and this gene's expression

Tissue	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
DLPFC	2.18581276965834e-19	0.481381267275704	1.37173269541754e-06	0.27024427518394	2.0807540611161e-44	0.685795475748007
AC	2.83604093565064e-53	0.784006336517113	8.69602078976164e-29	0.627615606475669	1.02761732307903e-19	0.532554681690099
PCC	1.3413100913769e-17	0.566414923613804	5.94137486302665e-13	0.490438756873486	2.84653051324042e-11	0.457541467559391
CER	3.55170756982383e-37	0.81678294825094	2.50149892847926e-24	0.710247946198871	5.77982154582368e-05	0.322256396040514
TCX	7.47203152403346e-16	0.59697875005111	0.0906766834243415	0.138629951936364	3.09673892454108e-18	0.633958235201554
FP	2.28475274942686e-29	0.716814038023915	7.92522757528552e-24	0.662174362724411	2.50194650471367e-07	0.375015063050184
IFG	0.00379013486837954	0.557463236152193	0.0559254534568504	0.387083815958792	0.00126514780556286	0.607942350167251
PG	8.94860319546945e-43	0.800519255737982	1.96519128109402e-24	0.657855186787737	0.306992773462283	0.0753050988336872
STG	2.18358945940382e-10	0.624493866832238	0.000129943196153336	0.405502671386161	1.07684872218709e-06	0.50307185207492

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Relation with AD stages for MRE11

Correlation between AD stages and RNA editing frequency

Tissue	ADeditomID	position	P-val	Coeff.
CER	ADediting_292151	chr11_94416014_-	0.000938721525328007	0.31390526408414
CER	ADediting_292152	chr11_94416015_-	0.000320492504735258	0.339823085528709
CER	ADediting_292157	chr11_94416062_-	0.000390000460224482	0.335255736089324
TCX	ADediting_292150	chr11_94416004_-	0.000502039743842198	0.332259586690795
TCX	ADediting_292208	chr11_94417182_-	0.000681804073568967	0.324785012199263
IFG	ADediting_292178	chr11_94416736_-	0.010863982330732	0.50031768532811
IFG	ADediting_292185	chr11_94416807_-	0.0148640816869142	0.481271416761245
IFG	ADediting_292195	chr11_94417105_-	0.0354713369979928	0.422303326441651

Correlation between AD stages and this gene's expression

Tissue	P-val	Coeff.
CER	1.58115662049542e-06	0.442968117781781
TCX	7.6601390043043e-09	0.524877688132381

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RelatedDrugs for MRE11

Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for MRE11

Diseases associated with this gene.
(DisGeNet 4.0)

Gene	Disease ID	Disease name	# pubmeds	Source
MRE11	C1140680	Malignant neoplasm of ovary	6	CLINGEN;UNIPROT
MRE11	C0346153	Breast Cancer, Familial	5	CLINGEN
MRE11	C0039445	Hereditary hemorrhagic telangiectasia	3	GENOMICS_ENGLAND
MRE11	C0006826	Malignant Neoplasms	1	UNIPROT
MRE11	C0431350	Primary microcephaly	1	GENOMICS_ENGLAND
MRE11	C1858391	ATAXIA-TELANGIECTASIA-LIKE DISORDER	1	CTD_human;ORPHANET;UNIPROT
MRE11	C3714756	Intellectual Disability	1	GENOMICS_ENGLAND
MRE11	C4012790	Ataxia-Telangiectasisa-Like Disorder 1	1	UNIPROT

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Gene summary for MRE11

RNA A-to-I events for MRE11

RNA editing positional annotations for MRE11 using Annovar

RNA A-to-I editing events in the alternative splicing sites for MRE11

Differntial gene expression between RNA A-to-I edited versus non-edited samples for MRE11

Protein coding region RNA A-to-I editings for MRE11

The effects of the RNA editing to the miRNA binding sites for MRE11

The effects of the RNA editing to the stability of the RNA structures for MRE11

Relation with ADAR for MRE11

Relation with AD stages for MRE11

RelatedDrugs for MRE11

RelatedDiseases for MRE11

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited versus non-edited samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with AD stages
	Related drugs with this gene
	Related diseases with this gene