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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for MPV17

check button Gene summary
Gene informationGene symbol

MPV17

Gene ID

4358

Gene namemitochondrial inner membrane protein MPV17
SynonymsCMT2EE|MTDPS6|SYM1
Cytomap

2p23.3

Type of geneprotein-coding
Descriptionprotein Mpv17MPV17, mitochondrial inner membrane proteinMpV17 mitochondrial inner membrane proteinMpv17, human homolog of glomerulosclerosis and nephrotic syndrome
Modification date20200313
UniProtAcc

P39210,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for MPV17

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_864840(27310234, -), ADediting_864841(27310274, -), ADediting_864842(27310375, -), ADediting_864843(27313224, -), ADediting_864844(27313808, -), ADediting_864845(27313823, -), ADediting_864846(27313827, -), ADediting_864847(27313833, -), ADediting_864848(27313840, -), ADediting_864849(27313844, -), ADediting_864850(27313850, -), ADediting_864851(27313872, -), ADediting_864852(27313906, -), ADediting_864853(27313907, -), ADediting_864854(27313913, -), ADediting_864855(27313930, -), ADediting_864856(27313931, -), ADediting_864857(27313949, -), ADediting_864858(27313967, -), ADediting_864859(27313970, -), ADediting_864860(27313979, -), ADediting_864861(27313984, -), ADediting_864862(27313985, -), ADediting_864863(27314001, -), ADediting_864864(27314052, -), ADediting_864865(27314068, -), ADediting_864866(27314082, -), ADediting_864867(27314090, -), ADediting_864868(27314103, -), ADediting_864869(27314104, -), ADediting_864870(27314107, -), ADediting_864871(27314108, -), ADediting_864872(27314121, -), ADediting_864873(27314122, -), ADediting_864874(27314133, -), ADediting_864875(27314140, -), ADediting_864876(27314156, -), ADediting_864877(27314159, -), ADediting_864878(27314186, -), ADediting_864879(27314202, -), ADediting_864880(27314208, -), ADediting_864881(27314218, -), ADediting_864882(27314230, -), ADediting_864883(27314235, -), ADediting_864884(27314244, -), ADediting_864885(27314246, -), ADediting_864886(27314247, -), ADediting_864887(27314248, -), ADediting_864888(27314261, -), ADediting_864889(27314268, -), ADediting_864890(27314284, -), ADediting_864891(27314317, -), ADediting_864892(27314321, -), ADediting_864893(27314936, -), ADediting_864894(27315597, -), ADediting_864895(27315647, -), ADediting_864896(27315658, -), ADediting_864897(27315659, -), ADediting_864898(27315668, -), ADediting_864899(27315673, -), ADediting_864900(27315686, -), ADediting_864901(27315694, -), ADediting_864902(27315699, -), ADediting_864903(27315700, -), ADediting_864904(27315722, -), ADediting_864905(27315750, -), ADediting_864906(27315755, -), ADediting_864907(27315763, -), ADediting_864908(27315775, -), ADediting_864909(27315780, -), ADediting_864910(27315799, -), ADediting_864911(27315808, -), ADediting_864912(27315812, -), ADediting_864913(27315813, -), ADediting_864914(27315828, -), ADediting_864915(27315829, -), ADediting_864916(27315834, -), ADediting_864917(27315835, -), ADediting_864918(27315837, -), ADediting_864919(27318154, -), ADediting_864920(27318166, -), ADediting_864921(27318201, -), ADediting_864922(27318207, -), ADediting_864923(27318268, -), ADediting_864924(27318269, -), ADediting_864925(27318304, -), ADediting_864926(27318339, -), ADediting_864927(27318340, -), ADediting_864928(27318482, -), ADediting_864929(27318486, -), ADediting_864930(27318490, -), ADediting_864931(27318495, -), ADediting_864932(27318522, -), ADediting_864933(27318559, -), ADediting_864934(27318585, -), ADediting_864935(27318586, -), ADediting_864936(27318600, -), ADediting_864937(27318604, -), ADediting_864938(27318773, -), ADediting_864939(27318787, -), ADediting_864940(27318798, -), ADediting_864941(27318822, -), ADediting_864942(27318841, -), ADediting_864943(27318862, -), ADediting_864944(27318872, -), ADediting_864945(27318876, -), ADediting_864946(27318897, -), ADediting_864947(27318902, -), ADediting_864948(27318903, -), ADediting_864949(27318921, -), ADediting_864950(27318929, -), ADediting_864951(27318944, -), ADediting_864952(27318947, -), ADediting_864953(27318958, -), ADediting_864954(27318966, -), ADediting_864955(27319021, -), ADediting_864956(27319032, -), ADediting_864957(27319037, -), ADediting_864958(27319038, -), ADediting_864959(27319068, -), ADediting_864960(27319328, -), ADediting_864961(27319336, -), ADediting_864962(27319355, -), ADediting_864963(27319379, -), ADediting_864964(27319391, -), ADediting_864965(27319467, -), ADediting_864966(27319509, -), ADediting_864967(27319674, -), ADediting_864968(27319677, -), ADediting_864969(27319690, -), ADediting_864970(27319703, -), ADediting_864971(27319707, -), ADediting_864972(27319708, -), ADediting_864973(27319713, -), ADediting_864974(27319720, -), ADediting_864975(27319728, -), ADediting_864976(27319733, -), ADediting_864977(27319742, -), ADediting_864978(27319759, -), ADediting_864979(27319762, -), ADediting_864980(27319768, -), ADediting_864981(27319786, -), ADediting_864982(27319794, -), ADediting_864983(27319801, -), ADediting_864984(27319804, -), ADediting_864985(27319814, -), ADediting_864986(27319826, -), ADediting_864987(27319836, -), ADediting_864988(27319839, -), ADediting_864989(27319840, -), ADediting_864990(27319843, -), ADediting_864991(27319863, -), ADediting_864992(27319869, -), ADediting_864993(27319874, -), ADediting_864994(27319877, -), ADediting_864995(27319879, -), ADediting_864996(27319912, -), ADediting_864997(27319919, -), ADediting_864998(27319920, -), ADediting_864999(27319924, -), ADediting_865000(27319979, -), ADediting_865001(27319981, -), ADediting_865002(27319993, -), ADediting_865003(27319994, -), ADediting_865004(27320012, -), ADediting_865005(27320016, -), ADediting_865006(27320053, -), ADediting_865007(27320056, -), ADediting_865008(27320061, -), ADediting_865009(27320070, -), ADediting_865010(27320073, -), ADediting_865011(27320093, -), ADediting_865012(27320115, -), ADediting_865013(27320125, -), ADediting_865014(27320154, -), ADediting_865015(27320155, -), ADediting_865016(27320174, -), ADediting_865017(27320371, -), ADediting_865018(27320405, -), ADediting_865019(27320422, -), ADediting_865020(27320433, -), ADediting_865021(27320465, -), ADediting_865022(27320469, -), ADediting_865023(27320474, -), ADediting_865024(27320501, -), ADediting_865025(27320529, -), ADediting_865026(27320530, -), ADediting_865027(27320531, -), ADediting_865028(27320539, -), ADediting_865029(27320548, -), ADediting_865030(27320549, -), ADediting_865031(27320563, -), ADediting_865032(27320568, -), ADediting_865033(27320571, -), ADediting_865034(27320576, -), ADediting_865035(27320598, -), ADediting_865036(27320601, -), ADediting_865037(27320606, -), ADediting_865038(27320607, -), ADediting_865039(27320613, -), ADediting_865040(27321796, -), ADediting_1563138(27313809, -), ADediting_1563139(27313925, -), ADediting_1563140(27313939, -), ADediting_1563141(27313976, -), ADediting_1563142(27314120, -), ADediting_1563143(27314157, -), ADediting_1563144(27314206, -), ADediting_1563145(27314211, -), ADediting_1563146(27314221, -), ADediting_1563147(27315826, -), ADediting_1563148(27320364, -), ADediting_1636811(27315732, -), ADediting_1636812(27318776, -),

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RNA editing positional annotations for MPV17 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_864840chr2_27310234_-intronic
ADediting_864841chr2_27310274_-intronic
ADediting_864842chr2_27310375_-intronic
ADediting_864843chr2_27313224_-intronic
ADediting_864844chr2_27313808_-intronic
ADediting_864845chr2_27313823_-intronic
ADediting_864846chr2_27313827_-intronic
ADediting_864847chr2_27313833_-intronic
ADediting_864848chr2_27313840_-intronic
ADediting_864849chr2_27313844_-intronic
ADediting_864850chr2_27313850_-intronic
ADediting_864851chr2_27313872_-intronic
ADediting_864852chr2_27313906_-intronic
ADediting_864853chr2_27313907_-intronic
ADediting_864854chr2_27313913_-intronic
ADediting_864855chr2_27313930_-intronic
ADediting_864856chr2_27313931_-intronic
ADediting_864857chr2_27313949_-intronic
ADediting_864858chr2_27313967_-intronic
ADediting_864859chr2_27313970_-intronic
ADediting_864860chr2_27313979_-intronic
ADediting_864861chr2_27313984_-intronic
ADediting_864862chr2_27313985_-intronic
ADediting_864863chr2_27314001_-intronic
ADediting_864864chr2_27314052_-intronic
ADediting_864865chr2_27314068_-intronic
ADediting_864866chr2_27314082_-intronic
ADediting_864867chr2_27314090_-intronic
ADediting_864868chr2_27314103_-intronic
ADediting_864869chr2_27314104_-intronic
ADediting_864870chr2_27314107_-intronic
ADediting_864871chr2_27314108_-intronic
ADediting_864872chr2_27314121_-intronic
ADediting_864873chr2_27314122_-intronic
ADediting_864874chr2_27314133_-intronic
ADediting_864875chr2_27314140_-intronic
ADediting_864876chr2_27314156_-intronic
ADediting_864877chr2_27314159_-intronic
ADediting_864878chr2_27314186_-intronic
ADediting_864879chr2_27314202_-intronic
ADediting_864880chr2_27314208_-intronic
ADediting_864881chr2_27314218_-intronic
ADediting_864882chr2_27314230_-intronic
ADediting_864883chr2_27314235_-intronic
ADediting_864884chr2_27314244_-intronic
ADediting_864885chr2_27314246_-intronic
ADediting_864886chr2_27314247_-intronic
ADediting_864887chr2_27314248_-intronic
ADediting_864888chr2_27314261_-intronic
ADediting_864889chr2_27314268_-intronic
ADediting_864890chr2_27314284_-intronic
ADediting_864891chr2_27314317_-intronic
ADediting_864892chr2_27314321_-intronic
ADediting_864893chr2_27314936_-intronic
ADediting_864894chr2_27315597_-intronic
ADediting_864895chr2_27315647_-intronic
ADediting_864896chr2_27315658_-intronic
ADediting_864897chr2_27315659_-intronic
ADediting_864898chr2_27315668_-intronic
ADediting_864899chr2_27315673_-intronic
ADediting_864900chr2_27315686_-intronic
ADediting_864901chr2_27315694_-intronic
ADediting_864902chr2_27315699_-intronic
ADediting_864903chr2_27315700_-intronic
ADediting_864904chr2_27315722_-UTR3
ADediting_864905chr2_27315750_-UTR3
ADediting_864906chr2_27315755_-UTR3
ADediting_864907chr2_27315763_-UTR3
ADediting_864908chr2_27315775_-UTR3
ADediting_864909chr2_27315780_-UTR3
ADediting_864910chr2_27315799_-UTR3
ADediting_864911chr2_27315808_-UTR3
ADediting_864912chr2_27315812_-UTR3
ADediting_864913chr2_27315813_-UTR3
ADediting_864914chr2_27315828_-UTR3
ADediting_864915chr2_27315829_-UTR3
ADediting_864916chr2_27315834_-UTR3
ADediting_864917chr2_27315835_-UTR3
ADediting_864918chr2_27315837_-UTR3
ADediting_864919chr2_27318154_-intronic
ADediting_864920chr2_27318166_-intronic
ADediting_864921chr2_27318201_-intronic
ADediting_864922chr2_27318207_-intronic
ADediting_864923chr2_27318268_-intronic
ADediting_864924chr2_27318269_-intronic
ADediting_864925chr2_27318304_-intronic
ADediting_864926chr2_27318339_-intronic
ADediting_864927chr2_27318340_-intronic
ADediting_864928chr2_27318482_-intronic
ADediting_864929chr2_27318486_-intronic
ADediting_864930chr2_27318490_-intronic
ADediting_864931chr2_27318495_-intronic
ADediting_864932chr2_27318522_-intronic
ADediting_864933chr2_27318559_-intronic
ADediting_864934chr2_27318585_-intronic
ADediting_864935chr2_27318586_-intronic
ADediting_864936chr2_27318600_-intronic
ADediting_864937chr2_27318604_-intronic
ADediting_864938chr2_27318773_-intronic
ADediting_864939chr2_27318787_-intronic
ADediting_864940chr2_27318798_-intronic
ADediting_864941chr2_27318822_-intronic
ADediting_864942chr2_27318841_-intronic
ADediting_864943chr2_27318862_-intronic
ADediting_864944chr2_27318872_-intronic
ADediting_864945chr2_27318876_-intronic
ADediting_864946chr2_27318897_-intronic
ADediting_864947chr2_27318902_-intronic
ADediting_864948chr2_27318903_-intronic
ADediting_864949chr2_27318921_-intronic
ADediting_864950chr2_27318929_-intronic
ADediting_864951chr2_27318944_-intronic
ADediting_864952chr2_27318947_-intronic
ADediting_864953chr2_27318958_-intronic
ADediting_864954chr2_27318966_-intronic
ADediting_864955chr2_27319021_-intronic
ADediting_864956chr2_27319032_-intronic
ADediting_864957chr2_27319037_-intronic
ADediting_864958chr2_27319038_-intronic
ADediting_864959chr2_27319068_-intronic
ADediting_864960chr2_27319328_-intronic
ADediting_864961chr2_27319336_-intronic
ADediting_864962chr2_27319355_-intronic
ADediting_864963chr2_27319379_-intronic
ADediting_864964chr2_27319391_-intronic
ADediting_864965chr2_27319467_-intronic
ADediting_864966chr2_27319509_-intronic
ADediting_864967chr2_27319674_-intronic
ADediting_864968chr2_27319677_-intronic
ADediting_864969chr2_27319690_-intronic
ADediting_864970chr2_27319703_-intronic
ADediting_864971chr2_27319707_-intronic
ADediting_864972chr2_27319708_-intronic
ADediting_864973chr2_27319713_-intronic
ADediting_864974chr2_27319720_-intronic
ADediting_864975chr2_27319728_-intronic
ADediting_864976chr2_27319733_-intronic
ADediting_864977chr2_27319742_-intronic
ADediting_864978chr2_27319759_-intronic
ADediting_864979chr2_27319762_-intronic
ADediting_864980chr2_27319768_-intronic
ADediting_864981chr2_27319786_-intronic
ADediting_864982chr2_27319794_-intronic
ADediting_864983chr2_27319801_-intronic
ADediting_864984chr2_27319804_-intronic
ADediting_864985chr2_27319814_-intronic
ADediting_864986chr2_27319826_-intronic
ADediting_864987chr2_27319836_-intronic
ADediting_864988chr2_27319839_-intronic
ADediting_864989chr2_27319840_-intronic
ADediting_864990chr2_27319843_-intronic
ADediting_864991chr2_27319863_-intronic
ADediting_864992chr2_27319869_-intronic
ADediting_864993chr2_27319874_-intronic
ADediting_864994chr2_27319877_-intronic
ADediting_864995chr2_27319879_-intronic
ADediting_864996chr2_27319912_-intronic
ADediting_864997chr2_27319919_-intronic
ADediting_864998chr2_27319920_-intronic
ADediting_864999chr2_27319924_-intronic
ADediting_865000chr2_27319979_-intronic
ADediting_865001chr2_27319981_-intronic
ADediting_865002chr2_27319993_-intronic
ADediting_865003chr2_27319994_-intronic
ADediting_865004chr2_27320012_-intronic
ADediting_865005chr2_27320016_-intronic
ADediting_865006chr2_27320053_-intronic
ADediting_865007chr2_27320056_-intronic
ADediting_865008chr2_27320061_-intronic
ADediting_865009chr2_27320070_-intronic
ADediting_865010chr2_27320073_-intronic
ADediting_865011chr2_27320093_-intronic
ADediting_865012chr2_27320115_-intronic
ADediting_865013chr2_27320125_-intronic
ADediting_865014chr2_27320154_-intronic
ADediting_865015chr2_27320155_-intronic
ADediting_865016chr2_27320174_-intronic
ADediting_865017chr2_27320371_-intronic
ADediting_865018chr2_27320405_-intronic
ADediting_865019chr2_27320422_-intronic
ADediting_865020chr2_27320433_-intronic
ADediting_865021chr2_27320465_-intronic
ADediting_865022chr2_27320469_-intronic
ADediting_865023chr2_27320474_-intronic
ADediting_865024chr2_27320501_-intronic
ADediting_865025chr2_27320529_-intronic
ADediting_865026chr2_27320530_-intronic
ADediting_865027chr2_27320531_-intronic
ADediting_865028chr2_27320539_-intronic
ADediting_865029chr2_27320548_-intronic
ADediting_865030chr2_27320549_-intronic
ADediting_865031chr2_27320563_-intronic
ADediting_865032chr2_27320568_-intronic
ADediting_865033chr2_27320571_-intronic
ADediting_865034chr2_27320576_-intronic
ADediting_865035chr2_27320598_-intronic
ADediting_865036chr2_27320601_-intronic
ADediting_865037chr2_27320606_-intronic
ADediting_865038chr2_27320607_-intronic
ADediting_865039chr2_27320613_-intronic
ADediting_865040chr2_27321796_-intronic
ADediting_1563138chr2_27313809_-intronic
ADediting_1563139chr2_27313925_-intronic
ADediting_1563140chr2_27313939_-intronic
ADediting_1563141chr2_27313976_-intronic
ADediting_1563142chr2_27314120_-intronic
ADediting_1563143chr2_27314157_-intronic
ADediting_1563144chr2_27314206_-intronic
ADediting_1563145chr2_27314211_-intronic
ADediting_1563146chr2_27314221_-intronic
ADediting_1563147chr2_27315826_-UTR3
ADediting_1563148chr2_27320364_-intronic
ADediting_1636811chr2_27315732_-UTR3
ADediting_1636812chr2_27318776_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_864840chr2_27310234_-SINEAluName=AluSz
ADediting_864841chr2_27310274_-SINEAluName=AluSz
ADediting_864842chr2_27310375_-SINEAluName=AluSz
ADediting_864844chr2_27313808_-SINEAluName=AluSx1
ADediting_864845chr2_27313823_-SINEAluName=AluSx1
ADediting_864846chr2_27313827_-SINEAluName=AluSx1
ADediting_864847chr2_27313833_-SINEAluName=AluSx1
ADediting_864848chr2_27313840_-SINEAluName=AluSx1
ADediting_864849chr2_27313844_-SINEAluName=AluSx1
ADediting_864850chr2_27313850_-SINEAluName=AluSx1
ADediting_864851chr2_27313872_-SINEAluName=AluSx1
ADediting_864852chr2_27313906_-SINEAluName=AluSx1
ADediting_864853chr2_27313907_-SINEAluName=AluSx1
ADediting_864854chr2_27313913_-SINEAluName=AluSx1
ADediting_864855chr2_27313930_-SINEAluName=AluSx1
ADediting_864856chr2_27313931_-SINEAluName=AluSx1
ADediting_864857chr2_27313949_-SINEAluName=AluSx1
ADediting_864858chr2_27313967_-SINEAluName=AluSx1
ADediting_864859chr2_27313970_-SINEAluName=AluSx1
ADediting_864860chr2_27313979_-SINEAluName=AluSx1
ADediting_864861chr2_27313984_-SINEAluName=AluSx1
ADediting_864862chr2_27313985_-SINEAluName=AluSx1
ADediting_864863chr2_27314001_-SINEAluName=AluSx1
ADediting_864864chr2_27314052_-SINEAluName=AluJo
ADediting_864865chr2_27314068_-SINEAluName=AluJo
ADediting_864866chr2_27314082_-SINEAluName=AluJo
ADediting_864867chr2_27314090_-SINEAluName=AluJo
ADediting_864868chr2_27314103_-SINEAluName=AluJo
ADediting_864869chr2_27314104_-SINEAluName=AluJo
ADediting_864870chr2_27314107_-SINEAluName=AluJo
ADediting_864871chr2_27314108_-SINEAluName=AluJo
ADediting_864872chr2_27314121_-SINEAluName=AluJo
ADediting_864873chr2_27314122_-SINEAluName=AluJo
ADediting_864874chr2_27314133_-SINEAluName=AluJo
ADediting_864875chr2_27314140_-SINEAluName=AluJo
ADediting_864876chr2_27314156_-SINEAluName=AluJo
ADediting_864877chr2_27314159_-SINEAluName=AluJo
ADediting_864878chr2_27314186_-SINEAluName=AluJo
ADediting_864879chr2_27314202_-SINEAluName=AluJo
ADediting_864880chr2_27314208_-SINEAluName=AluJo
ADediting_864881chr2_27314218_-SINEAluName=AluJo
ADediting_864882chr2_27314230_-SINEAluName=AluJo
ADediting_864883chr2_27314235_-SINEAluName=AluJo
ADediting_864884chr2_27314244_-SINEAluName=AluJo
ADediting_864885chr2_27314246_-SINEAluName=AluJo
ADediting_864886chr2_27314247_-SINEAluName=AluJo
ADediting_864887chr2_27314248_-SINEAluName=AluJo
ADediting_864888chr2_27314261_-SINEAluName=AluJo
ADediting_864889chr2_27314268_-SINEAluName=AluJo
ADediting_864890chr2_27314284_-SINEAluName=AluJo
ADediting_864891chr2_27314317_-SINEAluName=AluJo
ADediting_864892chr2_27314321_-SINEAluName=AluJo
ADediting_864894chr2_27315597_-SINEAluName=AluSx1
ADediting_864895chr2_27315647_-SINEAluName=AluSx1
ADediting_864896chr2_27315658_-SINEAluName=AluSx1
ADediting_864897chr2_27315659_-SINEAluName=AluSx1
ADediting_864898chr2_27315668_-SINEAluName=AluSx1
ADediting_864899chr2_27315673_-SINEAluName=AluSx1
ADediting_864900chr2_27315686_-SINEAluName=AluSx1
ADediting_864901chr2_27315694_-SINEAluName=AluSx1
ADediting_864902chr2_27315699_-SINEAluName=AluSx1
ADediting_864903chr2_27315700_-SINEAluName=AluSx1
ADediting_864904chr2_27315722_-SINEAluName=AluSx1
ADediting_864905chr2_27315750_-SINEAluName=AluSx1
ADediting_864906chr2_27315755_-SINEAluName=AluSx1
ADediting_864907chr2_27315763_-SINEAluName=AluSx1
ADediting_864908chr2_27315775_-SINEAluName=AluSx1
ADediting_864909chr2_27315780_-SINEAluName=AluSx1
ADediting_864910chr2_27315799_-SINEAluName=AluSx1
ADediting_864911chr2_27315808_-SINEAluName=AluSx1
ADediting_864912chr2_27315812_-SINEAluName=AluSx1
ADediting_864913chr2_27315813_-SINEAluName=AluSx1
ADediting_864914chr2_27315828_-SINEAluName=AluSx1
ADediting_864915chr2_27315829_-SINEAluName=AluSx1
ADediting_864916chr2_27315834_-SINEAluName=AluSx1
ADediting_864917chr2_27315835_-SINEAluName=AluSx1
ADediting_864918chr2_27315837_-SINEAluName=AluSx1
ADediting_864919chr2_27318154_-SINEAluName=AluSx1
ADediting_864920chr2_27318166_-SINEAluName=AluSx1
ADediting_864921chr2_27318201_-SINEAluName=AluSx1
ADediting_864922chr2_27318207_-SINEAluName=AluSx1
ADediting_864923chr2_27318268_-SINEAluName=AluSx1
ADediting_864924chr2_27318269_-SINEAluName=AluSx1
ADediting_864925chr2_27318304_-SINEAluName=AluSx1
ADediting_864926chr2_27318339_-SINEAluName=AluSx1
ADediting_864927chr2_27318340_-SINEAluName=AluSx1
ADediting_864928chr2_27318482_-SINEAluName=AluSz
ADediting_864929chr2_27318486_-SINEAluName=AluSz
ADediting_864930chr2_27318490_-SINEAluName=AluSz
ADediting_864931chr2_27318495_-SINEAluName=AluSz
ADediting_864932chr2_27318522_-SINEAluName=AluSz
ADediting_864933chr2_27318559_-SINEAluName=AluSz
ADediting_864934chr2_27318585_-SINEAluName=AluSz
ADediting_864935chr2_27318586_-SINEAluName=AluSz
ADediting_864936chr2_27318600_-SINEAluName=AluSz
ADediting_864937chr2_27318604_-SINEAluName=AluSz
ADediting_864938chr2_27318773_-SINEAluName=AluSx1
ADediting_864939chr2_27318787_-SINEAluName=AluSx1
ADediting_864940chr2_27318798_-SINEAluName=AluSx1
ADediting_864941chr2_27318822_-SINEAluName=AluSx1
ADediting_864942chr2_27318841_-SINEAluName=AluSx1
ADediting_864943chr2_27318862_-SINEAluName=AluSx1
ADediting_864944chr2_27318872_-SINEAluName=AluSx1
ADediting_864945chr2_27318876_-SINEAluName=AluSx1
ADediting_864946chr2_27318897_-SINEAluName=AluSx1
ADediting_864947chr2_27318902_-SINEAluName=AluSx1
ADediting_864948chr2_27318903_-SINEAluName=AluSx1
ADediting_864949chr2_27318921_-SINEAluName=AluSx1
ADediting_864950chr2_27318929_-SINEAluName=AluSx1
ADediting_864951chr2_27318944_-SINEAluName=AluSx1
ADediting_864952chr2_27318947_-SINEAluName=AluSx1
ADediting_864953chr2_27318958_-SINEAluName=AluSx1
ADediting_864954chr2_27318966_-SINEAluName=AluSx1
ADediting_864955chr2_27319021_-SINEAluName=AluSx1
ADediting_864956chr2_27319032_-SINEAluName=AluSx1
ADediting_864957chr2_27319037_-SINEAluName=AluSx1
ADediting_864958chr2_27319038_-SINEAluName=AluSx1
ADediting_864960chr2_27319328_-SINEAluName=AluJo
ADediting_864961chr2_27319336_-SINEAluName=AluJo
ADediting_864962chr2_27319355_-SINEAluName=AluJo
ADediting_864963chr2_27319379_-SINEAluName=AluJo
ADediting_864964chr2_27319391_-SINEAluName=AluJo
ADediting_864965chr2_27319467_-SINEAluName=AluJo
ADediting_864966chr2_27319509_-SINEAluName=AluJo
ADediting_864967chr2_27319674_-SINEAluName=AluSz
ADediting_864968chr2_27319677_-SINEAluName=AluSz
ADediting_864969chr2_27319690_-SINEAluName=AluSz
ADediting_864970chr2_27319703_-SINEAluName=AluSz
ADediting_864971chr2_27319707_-SINEAluName=AluSz
ADediting_864972chr2_27319708_-SINEAluName=AluSz
ADediting_864973chr2_27319713_-SINEAluName=AluSz
ADediting_864974chr2_27319720_-SINEAluName=AluSz
ADediting_864975chr2_27319728_-SINEAluName=AluSz
ADediting_864976chr2_27319733_-SINEAluName=AluSz
ADediting_864977chr2_27319742_-SINEAluName=AluSz
ADediting_864978chr2_27319759_-SINEAluName=AluSz
ADediting_864979chr2_27319762_-SINEAluName=AluSz
ADediting_864980chr2_27319768_-SINEAluName=AluSz
ADediting_864981chr2_27319786_-SINEAluName=AluSz
ADediting_864982chr2_27319794_-SINEAluName=AluSz
ADediting_864983chr2_27319801_-SINEAluName=AluSz
ADediting_864984chr2_27319804_-SINEAluName=AluSz
ADediting_864985chr2_27319814_-SINEAluName=AluSz
ADediting_864986chr2_27319826_-SINEAluName=AluSz
ADediting_864987chr2_27319836_-SINEAluName=AluSz
ADediting_864988chr2_27319839_-SINEAluName=AluSz
ADediting_864989chr2_27319840_-SINEAluName=AluSz
ADediting_864990chr2_27319843_-SINEAluName=AluSz
ADediting_864991chr2_27319863_-SINEAluName=AluSz
ADediting_864992chr2_27319869_-SINEAluName=AluSz
ADediting_864993chr2_27319874_-SINEAluName=AluSz
ADediting_864994chr2_27319877_-SINEAluName=AluSz
ADediting_864995chr2_27319879_-SINEAluName=AluSz
ADediting_864996chr2_27319912_-SINEAluName=AluSz
ADediting_864997chr2_27319919_-SINEAluName=AluSz
ADediting_864998chr2_27319920_-SINEAluName=AluSz
ADediting_864999chr2_27319924_-SINEAluName=AluSz
ADediting_865000chr2_27319979_-SINEAluName=AluSx3
ADediting_865001chr2_27319981_-SINEAluName=AluSx3
ADediting_865002chr2_27319993_-SINEAluName=AluSx3
ADediting_865003chr2_27319994_-SINEAluName=AluSx3
ADediting_865004chr2_27320012_-SINEAluName=AluSx3
ADediting_865005chr2_27320016_-SINEAluName=AluSx3
ADediting_865006chr2_27320053_-SINEAluName=AluSx3
ADediting_865007chr2_27320056_-SINEAluName=AluSx3
ADediting_865008chr2_27320061_-SINEAluName=AluSx3
ADediting_865009chr2_27320070_-SINEAluName=AluSx3
ADediting_865010chr2_27320073_-SINEAluName=AluSx3
ADediting_865011chr2_27320093_-SINEAluName=AluSx3
ADediting_865012chr2_27320115_-SINEAluName=AluSx3
ADediting_865013chr2_27320125_-SINEAluName=AluSx3
ADediting_865014chr2_27320154_-SINEAluName=AluSx3
ADediting_865015chr2_27320155_-SINEAluName=AluSx3
ADediting_865016chr2_27320174_-SINEAluName=AluSx3
ADediting_865017chr2_27320371_-SINEAluName=AluSc8
ADediting_865018chr2_27320405_-SINEAluName=AluSc8
ADediting_865019chr2_27320422_-SINEAluName=AluSc8
ADediting_865020chr2_27320433_-SINEAluName=AluSc8
ADediting_865021chr2_27320465_-SINEAluName=AluSc8
ADediting_865022chr2_27320469_-SINEAluName=AluSc8
ADediting_865023chr2_27320474_-SINEAluName=AluSc8
ADediting_865024chr2_27320501_-SINEAluName=AluSc8
ADediting_865025chr2_27320529_-SINEAluName=AluSc8
ADediting_865026chr2_27320530_-SINEAluName=AluSc8
ADediting_865027chr2_27320531_-SINEAluName=AluSc8
ADediting_865028chr2_27320539_-SINEAluName=AluSc8
ADediting_865029chr2_27320548_-SINEAluName=AluSc8
ADediting_865030chr2_27320549_-SINEAluName=AluSc8
ADediting_865031chr2_27320563_-SINEAluName=AluSc8
ADediting_865032chr2_27320568_-SINEAluName=AluSc8
ADediting_865033chr2_27320571_-SINEAluName=AluSc8
ADediting_865034chr2_27320576_-SINEAluName=AluSc8
ADediting_865035chr2_27320598_-SINEAluName=AluSc8
ADediting_865036chr2_27320601_-SINEAluName=AluSc8
ADediting_865037chr2_27320606_-SINEAluName=AluSc8
ADediting_865038chr2_27320607_-SINEAluName=AluSc8
ADediting_865039chr2_27320613_-SINEAluName=AluSc8
ADediting_1563138chr2_27313809_-SINEAluName=AluSx1
ADediting_1563139chr2_27313925_-SINEAluName=AluSx1
ADediting_1563140chr2_27313939_-SINEAluName=AluSx1
ADediting_1563141chr2_27313976_-SINEAluName=AluSx1
ADediting_1563142chr2_27314120_-SINEAluName=AluJo
ADediting_1563143chr2_27314157_-SINEAluName=AluJo
ADediting_1563144chr2_27314206_-SINEAluName=AluJo
ADediting_1563145chr2_27314211_-SINEAluName=AluJo
ADediting_1563146chr2_27314221_-SINEAluName=AluJo
ADediting_1563147chr2_27315826_-SINEAluName=AluSx1
ADediting_1563148chr2_27320364_-SINEAluName=AluSc8
ADediting_1636811chr2_27315732_-SINEAluName=AluSx1
ADediting_1636812chr2_27318776_-SINEAluName=AluSx1

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RNA A-to-I editing events in the alternative splicing sites for MPV17

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for MPV17

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for MPV17

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for MPV17

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1636811chr2_27315732_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-4742-3pchr227315731273157388mer-1a2731573127315753142-9.18
ADediting_864904chr2_27315722_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-941chr227315719273157257mer-m82731571827315740150-25.8
ADediting_864905chr2_27315750_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-483-5pchr227315747273157537mer-m82731574627315767140-14.01
ADediting_864906chr2_27315755_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-412-3pchr227315755273157617mer-m82731575427315776153-19.82
ADediting_864906chr2_27315755_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-6754-3pchr227315755273157617mer-m82731575427315774144-16.46
ADediting_864912chr2_27315812_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-18a-3pchr227315807273158137mer-m82731580627315828148-20.51
ADediting_864912chr2_27315812_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-874-3pchr227315808273158147mer-m82731580727315830156-31.64
ADediting_864913chr2_27315813_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-1908-3pchr227315812273158198mer-1a2731581227315832145-20.14
ADediting_864913chr2_27315813_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-4665-3pchr227315812273158187mer-m82731581127315836145-29.96
ADediting_864914chr2_27315828_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-302a-3pchr227315823273158297mer-m82731582227315843151-15.62
ADediting_864914chr2_27315828_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-302b-3pchr227315823273158297mer-m82731582227315842145-9.46
ADediting_864914chr2_27315828_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-302c-3pchr227315823273158297mer-m82731582227315843143-11.96
ADediting_864914chr2_27315828_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-302d-3pchr227315823273158297mer-m82731582227315843147-12.36
ADediting_864914chr2_27315828_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-302echr227315823273158297mer-m82731582227315838141-8.62
ADediting_864914chr2_27315828_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-372-3pchr227315823273158297mer-m82731582227315849154-18.51
ADediting_864914chr2_27315828_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-373-3pchr227315823273158297mer-m82731582227315845168-23.27
ADediting_864914chr2_27315828_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-512-3pchr227315824273158307mer-m82731582327315847155-17.97
ADediting_864914chr2_27315828_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-520a-3pchr227315823273158297mer-m82731582227315843140-11.04
ADediting_864914chr2_27315828_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-520b-3pchr227315823273158297mer-m82731582227315843144-14.48
ADediting_864914chr2_27315828_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-520c-3pchr227315823273158297mer-m82731582227315842146-14.48
ADediting_864914chr2_27315828_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-520d-3pchr227315823273158297mer-m82731582227315845145-15.59
ADediting_864914chr2_27315828_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-520e-3pchr227315823273158297mer-m82731582227315842143-13.74
ADediting_864914chr2_27315828_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-6506-5pchr227315828273158347mer-m82731582727315849140-13.24
ADediting_864916chr2_27315834_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-625-3pchr227315833273158397mer-m82731583227315853140-11.35
ADediting_864917chr2_27315835_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-638chr227315829273158357mer-1a2731582927315855146-30.86
ADediting_864918chr2_27315837_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-10399-5pchr227315833273158397mer-m82731583227315853148-10.21
ADediting_864918chr2_27315837_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-3934-5pchr227315837273158437mer-m82731583627315855153-24.06
ADediting_864918chr2_27315837_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-552-3pchr227315835273158428mer-1a2731583527315855140-14.01
ADediting_864918chr2_27315837_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-6504-3pchr227315833273158397mer-m82731583227315853144-13.73

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1563147chr2_27315826_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-520g-3pchr227315821273158277mer-m82731582027315842151-12.26
ADediting_1563147chr2_27315826_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-520hchr227315821273158277mer-m82731582027315842146-9.86
ADediting_864904chr2_27315722_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-3085-3pchr227315721273157277mer-m82731572027315740144-14.81
ADediting_864904chr2_27315722_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-6504-5pchr227315721273157277mer-m82731572027315742148-17.22
ADediting_864905chr2_27315750_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-3170chr227315750273157567mer-m82731574927315773143-14.72
ADediting_864905chr2_27315750_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-6855-5pchr227315750273157567mer-m82731574927315775147-16.6
ADediting_864905chr2_27315750_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-6890-5pchr227315749273157557mer-m82731574827315768142-13.82
ADediting_864906chr2_27315755_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-193b-5pchr227315750273157578mer-1a2731575027315771142-13.06
ADediting_864906chr2_27315755_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-3170chr227315750273157567mer-m82731574927315773143-14.72
ADediting_864906chr2_27315755_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-6855-5pchr227315750273157567mer-m82731574927315775147-16.6
ADediting_864907chr2_27315763_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-4716-5pchr227315760273157667mer-m82731575927315780140-11.49
ADediting_864908chr2_27315775_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-3663-5pchr227315774273157807mer-m82731577327315792144-20.26
ADediting_864908chr2_27315775_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-6131chr227315773273157797mer-m82731577227315790140-16.72
ADediting_864908chr2_27315775_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-6843-3pchr227315775273157817mer-m82731577427315793152-20.48
ADediting_864908chr2_27315775_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-6848-3pchr227315775273157817mer-m82731577427315798143-25.71
ADediting_864909chr2_27315780_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-371a-5pchr227315778273157858mer-1a2731577827315797146-14.98
ADediting_864909chr2_27315780_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-6843-3pchr227315775273157817mer-m82731577427315793152-20.48
ADediting_864909chr2_27315780_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-6848-3pchr227315775273157817mer-m82731577427315798143-25.71
ADediting_864910chr2_27315799_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-125a-3pchr227315795273158017mer-m82731579427315815148-17.91
ADediting_864910chr2_27315799_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-640chr227315799273158057mer-m82731579827315814154-22.14
ADediting_864911chr2_27315808_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-6747-3pchr227315806273158127mer-m82731580527315824148-25.41
ADediting_864912chr2_27315812_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-212-5pchr227315810273158167mer-m82731580927315833154-19.36
ADediting_864913chr2_27315813_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-212-5pchr227315810273158167mer-m82731580927315833154-19.36
ADediting_864914chr2_27315828_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-4425chr227315826273158338mer-1a2731582627315847150-19.12
ADediting_864914chr2_27315828_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-6513-5pchr227315828273158347mer-m82731582727315849146-14.3
ADediting_864915chr2_27315829_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-4425chr227315826273158338mer-1a2731582627315847150-19.12
ADediting_864915chr2_27315829_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-5089-5pchr227315828273158358mer-1a2731582827315850148-13.67
ADediting_864915chr2_27315829_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-6513-5pchr227315828273158347mer-m82731582727315849146-14.3
ADediting_864916chr2_27315834_-ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-5089-5pchr227315828273158358mer-1a2731582827315850148-13.67

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1471003chr9_63819626_+ENSG00000115204.15ENST00000233545.6MPV17-201hsa-miR-4477bchr227309838273098458mer-1a2730983827309860159-16.62
ADediting_1471003chr9_63819626_+ENSG00000115204.15ENST00000357186.10MPV17-202hsa-miR-4477bchr227309838273098458mer-1a2730983827309860159-16.62
ADediting_1471003chr9_63819626_+ENSG00000115204.15ENST00000380044.6MPV17-203hsa-miR-4477bchr227309838273098458mer-1a2730983827309860159-16.62
ADediting_1471003chr9_63819626_+ENSG00000115204.15ENST00000402310.5MPV17-205hsa-miR-4477bchr227309838273098458mer-1a2730983827309860159-16.62
ADediting_1471003chr9_63819626_+ENSG00000115204.15ENST00000402722.5MPV17-206hsa-miR-4477bchr227309838273098458mer-1a2730983827309860159-16.62
ADediting_1471003chr9_63819626_+ENSG00000115204.15ENST00000405076.5MPV17-208hsa-miR-4477bchr227309838273098458mer-1a2730983827309860159-16.62
ADediting_1471003chr9_63819626_+ENSG00000115204.15ENST00000405983.5MPV17-209hsa-miR-4477bchr227309838273098458mer-1a2730983827309860159-16.62
ADediting_1471003chr9_63819626_+ENSG00000115204.15ENST00000430991.5MPV17-213hsa-miR-4477bchr227309838273098458mer-1a2730983827309860159-16.62
ADediting_843620chr2_207754818_+ENSG00000115204.15ENST00000399052.8MPV17-204hsa-miR-4775chr227315726273157327mer-m82731572527315747157-9.14

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for MPV17

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000399052.8protein_codingSoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_864904ENST00000399052.8chr2_27315722_-743-283.40-283.20-301.60
ADediting_1636811ENST00000399052.8chr2_27315732_-733-283.20-283.20-301.60
ADediting_864905ENST00000399052.8chr2_27315750_-715-284.20-283.20-301.60
ADediting_864906ENST00000399052.8chr2_27315755_-710-283.30-283.20-301.60
ADediting_864907ENST00000399052.8chr2_27315763_-702-282.90-283.20-301.60
ADediting_864908ENST00000399052.8chr2_27315775_-690-283.20-283.20-301.60
ADediting_864909ENST00000399052.8chr2_27315780_-685-286.80-283.20-301.60
ADediting_864910ENST00000399052.8chr2_27315799_-666-282.80-283.20-301.60
ADediting_864911ENST00000399052.8chr2_27315808_-657-285.00-283.20-301.60
ADediting_864912ENST00000399052.8chr2_27315812_-653-288.50-283.20-301.60
ADediting_864913ENST00000399052.8chr2_27315813_-652-285.10-283.20-301.60
ADediting_1563147ENST00000399052.8chr2_27315826_-639-286.60-283.20-301.60
ADediting_864914ENST00000399052.8chr2_27315828_-637-284.30-283.20-301.60
ADediting_864915ENST00000399052.8chr2_27315829_-636-282.90-283.20-301.60
ADediting_864916ENST00000399052.8chr2_27315834_-631-284.50-283.20-301.60
ADediting_864917ENST00000399052.8chr2_27315835_-630-285.00-283.20-301.60
ADediting_864918ENST00000399052.8chr2_27315837_-628-286.00-283.20-301.60

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for MPV17

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
TCXADediting_864844chr2_27313808_-0.4255202527968390.06554334304976260.0001021405791871590.3119035688757460.362768977375888-0.0748312206135285
DLPFCADediting_864845chr2_27313823_-4.38641523134195e-130.3960362729073268.44922960845148e-140.4070274925780870.007737094597000850.151008752253741
TCXADediting_864845chr2_27313823_-0.000140839162619470.3058899832905562.01963813223012e-060.3767159008899730.776896990183342-0.023328668078282
DLPFCADediting_864850chr2_27313850_-4.53440500380102e-090.3252362259114915.37290235045979e-080.3028269438022250.0002290401591685130.20782275810615
DLPFCADediting_864854chr2_27313913_-7.83118070027993e-100.3401098187091191.46778734864594e-050.2433964148794591.5045169711384e-110.370968180099818
DLPFCADediting_864856chr2_27313931_-2.7409437214405e-090.3295817413493514.30298321373402e-060.2576656042089941.50628009996045e-100.353388218821289
DLPFCADediting_864857chr2_27313949_-4.97391155706362e-090.3244301026861911.71554226081401e-050.2415194582538217.02187543417308e-100.341008037087429
DLPFCADediting_864858chr2_27313967_-1.64470306494716e-070.2920334438071077.62911328086965e-050.2227430573461119.07705902329421e-090.319129830604154
DLPFCADediting_864865chr2_27314068_-6.7435319326496e-140.4085012683451271.2325269190453e-160.4470342441594270.0009242107877216220.187234901917019
DLPFCADediting_864866chr2_27314082_-9.04120818955574e-050.2205037039048555.65944338351775e-080.3023353414606190.94743806234711-0.00375942484662978
DLPFCADediting_864867chr2_27314090_-2.27449264624404e-080.3108314211035543.00840082630759e-100.3478916833595711.87093030422771e-050.240469486845811
DLPFCADediting_864868chr2_27314103_-5.70150239355578e-070.2794899412317148.94725170379979e-110.357458144205720.8154628988764870.0133085212927656
DLPFCADediting_864869chr2_27314104_-1.10743290328307e-070.2959000806219521.05203389673139e-090.3376645632520020.00758588863740050.151380544161699
DLPFCADediting_864870chr2_27314107_-1.98015828105385e-080.3120997614213253.24669943888462e-090.3281275707068123.14521424076066e-050.234077683074706
DLPFCADediting_864871chr2_27314108_-6.35329327121491e-080.3012378386352083.06113299182928e-080.3080925755330190.02746844320503710.125236491538544
DLPFCADediting_864873chr2_27314122_-7.74379637590871e-090.3205395613641425.428113909109e-110.3613093984770520.0001586708115967870.212919523080902
DLPFCADediting_864874chr2_27314133_-1.65774836270223e-080.3137176090244736.96353841407212e-090.3214779910143260.0001546595238694820.213270593329185
DLPFCADediting_864881chr2_27314218_-8.86253324239921e-120.3748601374727235.58286440541405e-100.3428870816613630.0001094763800290890.217953190123317
DLPFCADediting_864882chr2_27314230_-9.7900797932799e-120.3741320941957433.00938693513258e-130.3985866694782825.85223590388971e-050.226194972223982
DLPFCADediting_864883chr2_27314235_-5.06558791731295e-120.3789180602469412.78827812439645e-140.4142046462328651.32790248762577e-060.270592397938308
DLPFCADediting_864884chr2_27314244_-1.36780404617428e-130.4038545199807831.36283146403823e-140.4187494137307612.88027827551854e-060.262156030485349
DLPFCADediting_864885chr2_27314246_-8.86682724399728e-120.374856598863363.97382911116833e-130.3967070499815222.49906836026373e-060.263724610434207
DLPFCADediting_864886chr2_27314247_-5.98228294632261e-110.3605642990556361.12907658225755e-120.3895380967638690.000226682538814390.207968101490484
DLPFCADediting_864887chr2_27314248_-1.93111132758527e-100.3514262992517381.14700275803316e-130.4050180670911960.009335961369805470.147429641895808
DLPFCADediting_864890chr2_27314284_-5.00694991942493e-120.3790019316138291.64526503867182e-140.4175603632457710.0001070530275078830.21825311765273
DLPFCADediting_864891chr2_27314317_-8.28857884254214e-090.3199371308294167.49580064260037e-100.3404705806293750.0002677702787904050.205615962433801
CERADediting_864891chr2_27314317_-4.36275031928537e-060.3650689321334980.007365483943062150.2179945836346620.2990273126887940.0853541018286898
TCXADediting_864891chr2_27314317_-0.0001452431411989940.3053067928389970.001434422067222480.2580064636469590.4165887476792690.0668131603402179
DLPFCADediting_864896chr2_27315658_-8.17600160851859e-110.358156643857454.59098985293867e-090.3251282982296440.0002768191532227790.205143532821996
CERADediting_864896chr2_27315658_-0.0001635354143377240.3030485856788790.09980674305206450.1348918275001340.0839666785459068-0.141573155729835
DLPFCADediting_864899chr2_27315673_-6.32498875554192e-100.3418660149323996.47709432453237e-100.3416711781227790.005196819816993820.158358124983709
TCXADediting_864899chr2_27315673_-0.02874219805885090.1786237767643261.5175962684287e-050.3451941378873450.8361923300631770.0170235894024645
DLPFCADediting_864900chr2_27315686_-1.9271883579805e-080.31234722838878.81961982511071e-070.2749381225187140.003573292906793880.165010065047935
DLPFCADediting_864902chr2_27315699_-1.17030015490563e-110.3728220976710711.63751974552522e-080.3138290207544530.0006023722434195980.193774656158073
DLPFCADediting_864903chr2_27315700_-1.05443956869918e-120.3900129591158323.38924790638363e-090.3277573548334430.001360616330091240.181135909032265
CERADediting_864910chr2_27315799_-0.0001054966143470350.3113042284319760.01608364244553690.1962582453332250.421952457137059-0.0660487125244379
CERADediting_864911chr2_27315808_-7.48110089654624e-050.317612039279530.01278541453129890.2028611973995160.125731002928121-0.125573386033579
DLPFCADediting_864913chr2_27315813_-4.45195065576061e-090.3253958541397243.6087530311143e-090.3272157792735710.01381802439652360.139707872254061
CERADediting_864913chr2_27315813_-3.72485336751247e-050.3299952563844730.03060248047582050.1766303036213490.238780802099352-0.0967701352347558
TCXADediting_864913chr2_27315813_-0.1690642004675240.1128710469421680.0001604635521665160.3034108165822810.894741148213906-0.0108936648752613
CERADediting_864915chr2_27315829_-0.0001378433833923240.3062964910429680.07562542752534570.145507248115650.166645103519926-0.113510975149418
TCXADediting_864915chr2_27315829_-9.11742538238743e-050.3139991206672320.0005766799513400390.2778364083803940.673701671278084-0.0346600922933578
CERADediting_864918chr2_27315837_-2.08900690036199e-050.3398755103030580.007830067104567190.2163636086756110.152460877575057-0.117409624291259
CERADediting_864961chr2_27319336_-2.89511484391718e-060.3713265457630010.04049826017993710.1674876162921810.947974279799091-0.00537261523282006
DLPFCADediting_864996chr2_27319912_-0.1619542705350250.07962660815839420.671685386914519-0.02416638013815289.54264081056048e-190.473728609695883
DLPFCADediting_865002chr2_27319993_-7.49861812849788e-060.2513121278007290.000649616436270960.1926363872705298.45303055851676e-110.357898638846648
DLPFCADediting_865003chr2_27319994_-0.005180847499468970.1584138009359790.1990353784137230.07314134151558719.94033522689479e-130.390421962859196
DLPFCADediting_865006chr2_27320053_-5.03895322637681e-050.2281196939375190.01169713880879410.1430326318145071.54146585853432e-100.353206449785147
DLPFCADediting_865010chr2_27320073_-0.09118143417829770.09610606783161160.4163432130590330.04632525418715571.64953838790127e-080.313762667261633
DLPFCADediting_865011chr2_27320093_-0.05724647413904720.1081136492971390.963052628510209-0.002641649413579584.01235563180403e-210.501222471428449
DLPFCADediting_865029chr2_27320548_-2.87233295896906e-060.2621866466879810.001320942406444890.1816093169156271.35507877767503e-090.335550582017401
DLPFCADediting_865030chr2_27320549_-0.01054423373922630.1450703374474160.1997916107136750.07301870596084411.49721254751361e-080.314640502100827

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC1.8169907103406e-240.5361321521065821.99344705537832e-540.7374221215786370.2554229020312950.064786781568812
AC6.24520792764466e-660.8338027097461313.17084632749389e-460.7489606558243054.09031805735992e-190.525042803542993
PCC8.45916767923907e-230.6332197191700245.0440673678363e-230.635775896005030.004710146391258650.203686624083319
TCX2.93375040562463e-150.5869599407091163.63077999388591e-100.4836239965501320.007693031092222280.216835559719115
FP4.04218836046552e-450.8231343335919713.27868784901714e-320.7406171861847517.57751061237741e-070.360699295254925
IFG6.38214776192793e-080.8523323791058634.42540757365001e-070.8229152217381920.05115380136656340.39425722177954
PG2.19914494381634e-450.8145407431667111.32607493426108e-340.7480976784530660.3564646355871060.0679933870236443
STG7.35907180006997e-230.8337682208067892.08054116525169e-110.6507221906364630.1412687206305180.16187313672208

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Relation with AD stages for MPV17

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.

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RelatedDrugs for MPV17

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for MPV17

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource
MPV17C0391976Pain Disorder6GENOMICS_ENGLAND
MPV17C1850406NAVAJO NEUROHEPATOPATHY4CTD_human;ORPHANET;UNIPROT
MPV17C1850407Navajo Familial Neurogenic Arthropathy4CTD_human;UNIPROT
MPV17C1112213Cholestasis in newborn3GENOMICS_ENGLAND
MPV17C0009197Cochlear Diseases1CTD_human
MPV17C0017668Focal glomerulosclerosis1CTD_human
MPV17C0022283Incontinentia Pigmenti Achromians1CTD_human
MPV17C0033687Proteinuria1CTD_human
MPV17C0036305Schamberg Disease1CTD_human
MPV17C0086432Hyalinosis, Segmental Glomerular1CTD_human
MPV17C0549567Pigmentation Disorders1CTD_human
MPV17C0751651Mitochondrial Diseases1CTD_human;GENOMICS_ENGLAND
MPV17C0949855Electron Transport Chain Deficiencies, Mitochondrial1CTD_human
MPV17C0949856Oxidative Phosphorylation Deficiencies1CTD_human
MPV17C0949857Mitochondrial Respiratory Chain Deficiencies1CTD_human