|
||||||
|
 | |
| |
| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
| |
| |
| The effects of the RNA editing to the stability of the RNA structures |
| |
| |
| |
|
Gene summary for MPST |
 Gene summary |
| Gene information | Gene symbol | MPST | Gene ID | 4357 |
| Gene name | mercaptopyruvate sulfurtransferase | |
| Synonyms | MST|TST2|TUM1 | |
| Cytomap | 22q12.3 | |
| Type of gene | protein-coding | |
| Description | 3-mercaptopyruvate sulfurtransferasehuman liver rhodanesetRNA thiouridin modification protein 1testicular tissue protein Li 200 | |
| Modification date | 20200313 | |
| UniProtAcc | P25325, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
RNA A-to-I events for MPST |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_988903(37027006, +), ADediting_988904(37027027, +), ADediting_988905(37027030, +), ADediting_988906(37027033, +), ADediting_988907(37027052, +), ADediting_988908(37027053, +), ADediting_988909(37027057, +), ADediting_988910(37027070, +), ADediting_988911(37027082, +), ADediting_988912(37027092, +), ADediting_988913(37027127, +), ADediting_988914(37027130, +), ADediting_988915(37027133, +), ADediting_988916(37027136, +), ADediting_988917(37027181, +), ADediting_988918(37027187, +), ADediting_988919(37027192, +), ADediting_988920(37027215, +), ADediting_988921(37027227, +), ADediting_988922(37027229, +), ADediting_988923(37027456, +), ADediting_988924(37027467, +), ADediting_988925(37028128, +), ADediting_988926(37028137, +), ADediting_988927(37028143, +), ADediting_988928(37028145, +), ADediting_988929(37028175, +), ADediting_988930(37028181, +), ADediting_988931(37028191, +), ADediting_988932(37028195, +), ADediting_988933(37028199, +), ADediting_988934(37028250, +), ADediting_988935(37028255, +), ADediting_988936(37028269, +), ADediting_988937(37028271, +), ADediting_988938(37028277, +), ADediting_988939(37028323, +), ADediting_988940(37028357, +), ADediting_988941(37028368, +), ADediting_988942(37028371, +), ADediting_988943(37028372, +), ADediting_988944(37028373, +), ADediting_988945(37028380, +), ADediting_988946(37028390, +), ADediting_988947(37028423, +), ADediting_988948(37028436, +), ADediting_988949(37028451, +), ADediting_988950(37028471, +), ADediting_988951(37028474, +), ADediting_988952(37028513, +), ADediting_988953(37028571, +), ADediting_988954(37028641, +), ADediting_988955(37028657, +), ADediting_1570482(37027214, +), ADediting_1570483(37027452, +), ADediting_1570484(37028123, +), ADediting_1570485(37028163, +), ADediting_1570486(37028377, +), ADediting_1570487(37028382, +), |
Top |
RNA editing positional annotations for MPST using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_988903 | chr22_37027006_+ | intronic |
| ADediting_988904 | chr22_37027027_+ | intronic |
| ADediting_988905 | chr22_37027030_+ | intronic |
| ADediting_988906 | chr22_37027033_+ | intronic |
| ADediting_988907 | chr22_37027052_+ | intronic |
| ADediting_988908 | chr22_37027053_+ | intronic |
| ADediting_988909 | chr22_37027057_+ | intronic |
| ADediting_988910 | chr22_37027070_+ | intronic |
| ADediting_988911 | chr22_37027082_+ | intronic |
| ADediting_988912 | chr22_37027092_+ | intronic |
| ADediting_988913 | chr22_37027127_+ | intronic |
| ADediting_988914 | chr22_37027130_+ | intronic |
| ADediting_988915 | chr22_37027133_+ | intronic |
| ADediting_988916 | chr22_37027136_+ | intronic |
| ADediting_988917 | chr22_37027181_+ | intronic |
| ADediting_988918 | chr22_37027187_+ | intronic |
| ADediting_988919 | chr22_37027192_+ | intronic |
| ADediting_988920 | chr22_37027215_+ | intronic |
| ADediting_988921 | chr22_37027227_+ | intronic |
| ADediting_988922 | chr22_37027229_+ | intronic |
| ADediting_988923 | chr22_37027456_+ | intronic |
| ADediting_988924 | chr22_37027467_+ | intronic |
| ADediting_988925 | chr22_37028128_+ | intronic |
| ADediting_988926 | chr22_37028137_+ | intronic |
| ADediting_988927 | chr22_37028143_+ | intronic |
| ADediting_988928 | chr22_37028145_+ | intronic |
| ADediting_988929 | chr22_37028175_+ | intronic |
| ADediting_988930 | chr22_37028181_+ | intronic |
| ADediting_988931 | chr22_37028191_+ | intronic |
| ADediting_988932 | chr22_37028195_+ | intronic |
| ADediting_988933 | chr22_37028199_+ | intronic |
| ADediting_988934 | chr22_37028250_+ | intronic |
| ADediting_988935 | chr22_37028255_+ | intronic |
| ADediting_988936 | chr22_37028269_+ | intronic |
| ADediting_988937 | chr22_37028271_+ | intronic |
| ADediting_988938 | chr22_37028277_+ | intronic |
| ADediting_988939 | chr22_37028323_+ | intronic |
| ADediting_988940 | chr22_37028357_+ | intronic |
| ADediting_988941 | chr22_37028368_+ | intronic |
| ADediting_988942 | chr22_37028371_+ | intronic |
| ADediting_988943 | chr22_37028372_+ | intronic |
| ADediting_988944 | chr22_37028373_+ | intronic |
| ADediting_988945 | chr22_37028380_+ | intronic |
| ADediting_988946 | chr22_37028390_+ | intronic |
| ADediting_988947 | chr22_37028423_+ | intronic |
| ADediting_988948 | chr22_37028436_+ | intronic |
| ADediting_988949 | chr22_37028451_+ | intronic |
| ADediting_988950 | chr22_37028471_+ | intronic |
| ADediting_988951 | chr22_37028474_+ | intronic |
| ADediting_988952 | chr22_37028513_+ | intronic |
| ADediting_988953 | chr22_37028571_+ | intronic |
| ADediting_988954 | chr22_37028641_+ | intronic |
| ADediting_988955 | chr22_37028657_+ | intronic |
| ADediting_1570482 | chr22_37027214_+ | intronic |
| ADediting_1570483 | chr22_37027452_+ | intronic |
| ADediting_1570484 | chr22_37028123_+ | intronic |
| ADediting_1570485 | chr22_37028163_+ | intronic |
| ADediting_1570486 | chr22_37028377_+ | intronic |
| ADediting_1570487 | chr22_37028382_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_988903 | chr22_37027006_+ | SINE | Alu | Name=AluSp |
| ADediting_988904 | chr22_37027027_+ | SINE | Alu | Name=AluSp |
| ADediting_988905 | chr22_37027030_+ | SINE | Alu | Name=AluSp |
| ADediting_988906 | chr22_37027033_+ | SINE | Alu | Name=AluSp |
| ADediting_988907 | chr22_37027052_+ | SINE | Alu | Name=AluSp |
| ADediting_988908 | chr22_37027053_+ | SINE | Alu | Name=AluSp |
| ADediting_988909 | chr22_37027057_+ | SINE | Alu | Name=AluSp |
| ADediting_988910 | chr22_37027070_+ | SINE | Alu | Name=AluSp |
| ADediting_988911 | chr22_37027082_+ | SINE | Alu | Name=AluSp |
| ADediting_988912 | chr22_37027092_+ | SINE | Alu | Name=AluSp |
| ADediting_988913 | chr22_37027127_+ | SINE | Alu | Name=AluSp |
| ADediting_988914 | chr22_37027130_+ | SINE | Alu | Name=AluSp |
| ADediting_988915 | chr22_37027133_+ | SINE | Alu | Name=AluSp |
| ADediting_988916 | chr22_37027136_+ | SINE | Alu | Name=AluSp |
| ADediting_988917 | chr22_37027181_+ | SINE | Alu | Name=AluSp |
| ADediting_988918 | chr22_37027187_+ | SINE | Alu | Name=AluSp |
| ADediting_988919 | chr22_37027192_+ | SINE | Alu | Name=AluSp |
| ADediting_988920 | chr22_37027215_+ | SINE | Alu | Name=AluSp |
| ADediting_988921 | chr22_37027227_+ | SINE | Alu | Name=AluSp |
| ADediting_988922 | chr22_37027229_+ | SINE | Alu | Name=AluSp |
| ADediting_988923 | chr22_37027456_+ | SINE | Alu | Name=AluJo |
| ADediting_988924 | chr22_37027467_+ | SINE | Alu | Name=AluJo |
| ADediting_988925 | chr22_37028128_+ | SINE | Alu | Name=AluJb |
| ADediting_988926 | chr22_37028137_+ | SINE | Alu | Name=AluJb |
| ADediting_988927 | chr22_37028143_+ | SINE | Alu | Name=AluJb |
| ADediting_988928 | chr22_37028145_+ | SINE | Alu | Name=AluJb |
| ADediting_988929 | chr22_37028175_+ | SINE | Alu | Name=AluJb |
| ADediting_988930 | chr22_37028181_+ | SINE | Alu | Name=AluJb |
| ADediting_988931 | chr22_37028191_+ | SINE | Alu | Name=AluJb |
| ADediting_988932 | chr22_37028195_+ | SINE | Alu | Name=AluJb |
| ADediting_988933 | chr22_37028199_+ | SINE | Alu | Name=AluJb |
| ADediting_988934 | chr22_37028250_+ | SINE | Alu | Name=AluJb |
| ADediting_988935 | chr22_37028255_+ | SINE | Alu | Name=AluSq |
| ADediting_988936 | chr22_37028269_+ | SINE | Alu | Name=AluSq |
| ADediting_988937 | chr22_37028271_+ | SINE | Alu | Name=AluSq |
| ADediting_988938 | chr22_37028277_+ | SINE | Alu | Name=AluSq |
| ADediting_988939 | chr22_37028323_+ | SINE | Alu | Name=AluSq |
| ADediting_988940 | chr22_37028357_+ | SINE | Alu | Name=AluSq |
| ADediting_988941 | chr22_37028368_+ | SINE | Alu | Name=AluSq |
| ADediting_988942 | chr22_37028371_+ | SINE | Alu | Name=AluSq |
| ADediting_988943 | chr22_37028372_+ | SINE | Alu | Name=AluSq |
| ADediting_988944 | chr22_37028373_+ | SINE | Alu | Name=AluSq |
| ADediting_988945 | chr22_37028380_+ | SINE | Alu | Name=AluSq |
| ADediting_988946 | chr22_37028390_+ | SINE | Alu | Name=AluSq |
| ADediting_988947 | chr22_37028423_+ | SINE | Alu | Name=AluSq |
| ADediting_988948 | chr22_37028436_+ | SINE | Alu | Name=AluSq |
| ADediting_988949 | chr22_37028451_+ | SINE | Alu | Name=AluSq |
| ADediting_988950 | chr22_37028471_+ | SINE | Alu | Name=AluSq |
| ADediting_988951 | chr22_37028474_+ | SINE | Alu | Name=AluSq |
| ADediting_988952 | chr22_37028513_+ | SINE | Alu | Name=AluSq |
| ADediting_988953 | chr22_37028571_+ | SINE | Alu | Name=AluJb |
| ADediting_988954 | chr22_37028641_+ | SINE | Alu | Name=AluJb |
| ADediting_988955 | chr22_37028657_+ | SINE | Alu | Name=AluJb |
| ADediting_1570482 | chr22_37027214_+ | SINE | Alu | Name=AluSp |
| ADediting_1570483 | chr22_37027452_+ | SINE | Alu | Name=AluJo |
| ADediting_1570484 | chr22_37028123_+ | SINE | Alu | Name=AluJb |
| ADediting_1570485 | chr22_37028163_+ | SINE | Alu | Name=AluJb |
| ADediting_1570486 | chr22_37028377_+ | SINE | Alu | Name=AluSq |
| ADediting_1570487 | chr22_37028382_+ | SINE | Alu | Name=AluSq |
Top |
RNA A-to-I editing events in the alternative splicing sites for MPST |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| ES | ADediting_988918 | chr22_37027187_+ | 37027186:37027194 | 5ss | 2e | CAGGTAATC | 6.99 | CGGGTAATC | 4.59 |
| ES | ADediting_988918 | chr22_37027187_+ | 37027186:37027194 | 5ss | 2e | CAGGTAATC | 6.99 | CGGGTAATC | 4.59 |
| ES | ADediting_988918 | chr22_37027187_+ | 37027186:37027194 | 5ss | 2e | CAGGTAATC | 6.99 | CGGGTAATC | 4.59 |
| ES | ADediting_988918 | chr22_37027187_+ | 37027186:37027194 | 5ss | 2e | CAGGTAATC | 6.99 | CGGGTAATC | 4.59 |
| ES | ADediting_988918 | chr22_37027187_+ | 37027186:37027194 | 5ss | 2e | CAGGTAATC | 6.99 | CGGGTAATC | 4.59 |
| ES | ADediting_988919 | chr22_37027192_+ | 37027186:37027194 | 5ss | 4i | CAGGTAATC | 6.99 | CAGGTAGTC | 5.30 |
| ES | ADediting_988919 | chr22_37027192_+ | 37027186:37027194 | 5ss | 4i | CAGGTAATC | 6.99 | CAGGTAGTC | 5.30 |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for MPST |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
 | |
 | |
 | |
 | |
 | |
 | |
 | |
 | |
| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |