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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for MEF2D

check button Gene summary
Gene informationGene symbol

MEF2D

Gene ID

4209

Gene namemyocyte enhancer factor 2D
Synonyms-
Cytomap

1q22

Type of geneprotein-coding
Descriptionmyocyte-specific enhancer factor 2DMADS box transcription enhancer factor 2, polypeptide D
Modification date20200322
UniProtAcc

Q14814,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
MEF2D

GO:0045944

positive regulation of transcription by RNA polymerase II

20590529


Top

RNA A-to-I events for MEF2D

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_35135(156469318, -), ADediting_35136(156469325, -), ADediting_35137(156469326, -), ADediting_35138(156469343, -), ADediting_35139(156469354, -), ADediting_35140(156469369, -), ADediting_35141(156469379, -), ADediting_35142(156469386, -), ADediting_35143(156469390, -), ADediting_35144(156469395, -), ADediting_35145(156469396, -), ADediting_35146(156469422, -), ADediting_35147(156469426, -), ADediting_35148(156469454, -), ADediting_35149(156469457, -), ADediting_35150(156469471, -), ADediting_35151(156469476, -), ADediting_35152(156469525, -), ADediting_35153(156469530, -), ADediting_35154(156469644, -), ADediting_35155(156469645, -), ADediting_35156(156469671, -), ADediting_35157(156469672, -), ADediting_35158(156469764, -), ADediting_35159(156469773, -), ADediting_35160(156469774, -), ADediting_35161(156469786, -), ADediting_35162(156469799, -), ADediting_35163(156469800, -), ADediting_35164(156469803, -), ADediting_35165(156469810, -), ADediting_35166(156469817, -), ADediting_35167(156469818, -), ADediting_35168(156469824, -), ADediting_35169(156469834, -), ADediting_35170(156469836, -), ADediting_35171(156469842, -), ADediting_35172(156469874, -), ADediting_35173(156470223, -), ADediting_35174(156470240, -), ADediting_35175(156470254, -), ADediting_35176(156470256, -), ADediting_35177(156470257, -), ADediting_35178(156470263, -), ADediting_35179(156470272, -), ADediting_35180(156470273, -), ADediting_35181(156470295, -), ADediting_35182(156470297, -), ADediting_35183(156470318, -), ADediting_35184(156470319, -), ADediting_35185(156470332, -), ADediting_35186(156470333, -), ADediting_35187(156470337, -), ADediting_35188(156470343, -), ADediting_35189(156470350, -), ADediting_35190(156470357, -), ADediting_35191(156470381, -), ADediting_35192(156470416, -), ADediting_35193(156471093, -), ADediting_35194(156471113, -), ADediting_35195(156471121, -), ADediting_35196(156471131, -), ADediting_35197(156471132, -), ADediting_35198(156471152, -), ADediting_35199(156471161, -), ADediting_35200(156471167, -), ADediting_35201(156471251, -), ADediting_35202(156471268, -), ADediting_35203(156471269, -), ADediting_35204(156471271, -), ADediting_35205(156471295, -), ADediting_35206(156471301, -), ADediting_35207(156471304, -), ADediting_35208(156471307, -), ADediting_35209(156471324, -), ADediting_35210(156471326, -), ADediting_35211(156471327, -), ADediting_35212(156471344, -), ADediting_35213(156471349, -), ADediting_35214(156471350, -), ADediting_35215(156471924, -), ADediting_35222(156472559, -), ADediting_35224(156472687, -), ADediting_35225(156472713, -), ADediting_35227(156472777, -), ADediting_35228(156472838, -), ADediting_35229(156472847, -), ADediting_35230(156472848, -), ADediting_35231(156472858, -), ADediting_35233(156472911, -), ADediting_35234(156472998, -), ADediting_35235(156473103, -), ADediting_35236(156473135, -), ADediting_35237(156473156, -), ADediting_35238(156473162, -), ADediting_35239(156473166, -), ADediting_35240(156473172, -), ADediting_35241(156473181, -), ADediting_35242(156473182, -), ADediting_35243(156473186, -), ADediting_35244(156473191, -), ADediting_35245(156473200, -), ADediting_35246(156473225, -), ADediting_35247(156473243, -), ADediting_35250(156474200, -), ADediting_35251(156474206, -), ADediting_35252(156474218, -), ADediting_35253(156474246, -), ADediting_35254(156474266, -), ADediting_35255(156474277, -), ADediting_35256(156474283, -), ADediting_35257(156474300, -), ADediting_35258(156474301, -), ADediting_35259(156474321, -), ADediting_35260(156474327, -), ADediting_35261(156474337, -), ADediting_35262(156474349, -), ADediting_35263(156474367, -), ADediting_35264(156474392, -), ADediting_35265(156474405, -), ADediting_35266(156474436, -), ADediting_35267(156474636, -), ADediting_35268(156474750, -), ADediting_35269(156474758, -), ADediting_35270(156474774, -), ADediting_35271(156474796, -), ADediting_35272(156475821, -), ADediting_35273(156476045, -), ADediting_35285(156495572, -), ADediting_1515803(156469320, -), ADediting_1515804(156469373, -), ADediting_1515805(156469382, -), ADediting_1515806(156469433, -), ADediting_1515807(156469446, -), ADediting_1515808(156469462, -), ADediting_1515809(156469490, -), ADediting_1515810(156469683, -), ADediting_1515811(156469722, -), ADediting_1515812(156469740, -), ADediting_1515813(156469804, -), ADediting_1515814(156469869, -), ADediting_1515815(156470907, -), ADediting_1515816(156471236, -), ADediting_1515817(156471334, -), ADediting_1515818(156472601, -), ADediting_1515819(156472982, -), ADediting_1515820(156473129, -), ADediting_1515821(156473187, -), ADediting_1515822(156473194, -), ADediting_1515823(156473197, -), ADediting_1515824(156473206, -), ADediting_1515825(156473287, -), ADediting_1515826(156473294, -), ADediting_1515827(156474244, -), ADediting_1515828(156474245, -), ADediting_1515829(156474286, -), ADediting_1515830(156474325, -), ADediting_1515831(156474356, -), ADediting_1515832(156474386, -), ADediting_1515833(156474423, -), ADediting_1515834(156474427, -), ADediting_1515835(156474442, -), ADediting_1515836(156474614, -), ADediting_1515837(156474682, -), ADediting_1515838(156474788, -), ADediting_1515839(156495589, -), ADediting_1596674(156473195, -),

Top

RNA editing positional annotations for MEF2D using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_35135chr1_156469318_-intronic
ADediting_35136chr1_156469325_-intronic
ADediting_35137chr1_156469326_-intronic
ADediting_35138chr1_156469343_-intronic
ADediting_35139chr1_156469354_-intronic
ADediting_35140chr1_156469369_-intronic
ADediting_35141chr1_156469379_-intronic
ADediting_35142chr1_156469386_-intronic
ADediting_35143chr1_156469390_-intronic
ADediting_35144chr1_156469395_-intronic
ADediting_35145chr1_156469396_-intronic
ADediting_35146chr1_156469422_-intronic
ADediting_35147chr1_156469426_-intronic
ADediting_35148chr1_156469454_-intronic
ADediting_35149chr1_156469457_-intronic
ADediting_35150chr1_156469471_-intronic
ADediting_35151chr1_156469476_-intronic
ADediting_35152chr1_156469525_-intronic
ADediting_35153chr1_156469530_-intronic
ADediting_35154chr1_156469644_-intronic
ADediting_35155chr1_156469645_-intronic
ADediting_35156chr1_156469671_-intronic
ADediting_35157chr1_156469672_-intronic
ADediting_35158chr1_156469764_-intronic
ADediting_35159chr1_156469773_-intronic
ADediting_35160chr1_156469774_-intronic
ADediting_35161chr1_156469786_-intronic
ADediting_35162chr1_156469799_-intronic
ADediting_35163chr1_156469800_-intronic
ADediting_35164chr1_156469803_-intronic
ADediting_35165chr1_156469810_-intronic
ADediting_35166chr1_156469817_-intronic
ADediting_35167chr1_156469818_-intronic
ADediting_35168chr1_156469824_-intronic
ADediting_35169chr1_156469834_-intronic
ADediting_35170chr1_156469836_-intronic
ADediting_35171chr1_156469842_-intronic
ADediting_35172chr1_156469874_-intronic
ADediting_35173chr1_156470223_-intronic
ADediting_35174chr1_156470240_-intronic
ADediting_35175chr1_156470254_-intronic
ADediting_35176chr1_156470256_-intronic
ADediting_35177chr1_156470257_-intronic
ADediting_35178chr1_156470263_-intronic
ADediting_35179chr1_156470272_-intronic
ADediting_35180chr1_156470273_-intronic
ADediting_35181chr1_156470295_-intronic
ADediting_35182chr1_156470297_-intronic
ADediting_35183chr1_156470318_-intronic
ADediting_35184chr1_156470319_-intronic
ADediting_35185chr1_156470332_-intronic
ADediting_35186chr1_156470333_-intronic
ADediting_35187chr1_156470337_-intronic
ADediting_35188chr1_156470343_-intronic
ADediting_35189chr1_156470350_-intronic
ADediting_35190chr1_156470357_-intronic
ADediting_35191chr1_156470381_-intronic
ADediting_35192chr1_156470416_-intronic
ADediting_35193chr1_156471093_-intronic
ADediting_35194chr1_156471113_-intronic
ADediting_35195chr1_156471121_-intronic
ADediting_35196chr1_156471131_-intronic
ADediting_35197chr1_156471132_-intronic
ADediting_35198chr1_156471152_-intronic
ADediting_35199chr1_156471161_-intronic
ADediting_35200chr1_156471167_-intronic
ADediting_35201chr1_156471251_-intronic
ADediting_35202chr1_156471268_-intronic
ADediting_35203chr1_156471269_-intronic
ADediting_35204chr1_156471271_-intronic
ADediting_35205chr1_156471295_-intronic
ADediting_35206chr1_156471301_-intronic
ADediting_35207chr1_156471304_-intronic
ADediting_35208chr1_156471307_-intronic
ADediting_35209chr1_156471324_-intronic
ADediting_35210chr1_156471326_-intronic
ADediting_35211chr1_156471327_-intronic
ADediting_35212chr1_156471344_-intronic
ADediting_35213chr1_156471349_-intronic
ADediting_35214chr1_156471350_-intronic
ADediting_35215chr1_156471924_-intronic
ADediting_35222chr1_156472559_-intronic
ADediting_35224chr1_156472687_-intronic
ADediting_35225chr1_156472713_-intronic
ADediting_35227chr1_156472777_-intronic
ADediting_35228chr1_156472838_-intronic
ADediting_35229chr1_156472847_-intronic
ADediting_35230chr1_156472848_-intronic
ADediting_35231chr1_156472858_-intronic
ADediting_35233chr1_156472911_-intronic
ADediting_35234chr1_156472998_-intronic
ADediting_35235chr1_156473103_-intronic
ADediting_35236chr1_156473135_-intronic
ADediting_35237chr1_156473156_-intronic
ADediting_35238chr1_156473162_-intronic
ADediting_35239chr1_156473166_-intronic
ADediting_35240chr1_156473172_-intronic
ADediting_35241chr1_156473181_-intronic
ADediting_35242chr1_156473182_-intronic
ADediting_35243chr1_156473186_-intronic
ADediting_35244chr1_156473191_-intronic
ADediting_35245chr1_156473200_-intronic
ADediting_35246chr1_156473225_-intronic
ADediting_35247chr1_156473243_-intronic
ADediting_35250chr1_156474200_-intronic
ADediting_35251chr1_156474206_-intronic
ADediting_35252chr1_156474218_-intronic
ADediting_35253chr1_156474246_-intronic
ADediting_35254chr1_156474266_-intronic
ADediting_35255chr1_156474277_-intronic
ADediting_35256chr1_156474283_-intronic
ADediting_35257chr1_156474300_-intronic
ADediting_35258chr1_156474301_-intronic
ADediting_35259chr1_156474321_-intronic
ADediting_35260chr1_156474327_-intronic
ADediting_35261chr1_156474337_-intronic
ADediting_35262chr1_156474349_-intronic
ADediting_35263chr1_156474367_-intronic
ADediting_35264chr1_156474392_-intronic
ADediting_35265chr1_156474405_-intronic
ADediting_35266chr1_156474436_-intronic
ADediting_35267chr1_156474636_-intronic
ADediting_35268chr1_156474750_-intronic
ADediting_35269chr1_156474758_-intronic
ADediting_35270chr1_156474774_-intronic
ADediting_35271chr1_156474796_-intronic
ADediting_35272chr1_156475821_-intronic
ADediting_35273chr1_156476045_-intronic
ADediting_35285chr1_156495572_-intronic
ADediting_1515803chr1_156469320_-intronic
ADediting_1515804chr1_156469373_-intronic
ADediting_1515805chr1_156469382_-intronic
ADediting_1515806chr1_156469433_-intronic
ADediting_1515807chr1_156469446_-intronic
ADediting_1515808chr1_156469462_-intronic
ADediting_1515809chr1_156469490_-intronic
ADediting_1515810chr1_156469683_-intronic
ADediting_1515811chr1_156469722_-intronic
ADediting_1515812chr1_156469740_-intronic
ADediting_1515813chr1_156469804_-intronic
ADediting_1515814chr1_156469869_-intronic
ADediting_1515815chr1_156470907_-intronic
ADediting_1515816chr1_156471236_-intronic
ADediting_1515817chr1_156471334_-intronic
ADediting_1515818chr1_156472601_-intronic
ADediting_1515819chr1_156472982_-intronic
ADediting_1515820chr1_156473129_-intronic
ADediting_1515821chr1_156473187_-intronic
ADediting_1515822chr1_156473194_-intronic
ADediting_1515823chr1_156473197_-intronic
ADediting_1515824chr1_156473206_-intronic
ADediting_1515825chr1_156473287_-intronic
ADediting_1515826chr1_156473294_-intronic
ADediting_1515827chr1_156474244_-intronic
ADediting_1515828chr1_156474245_-intronic
ADediting_1515829chr1_156474286_-intronic
ADediting_1515830chr1_156474325_-intronic
ADediting_1515831chr1_156474356_-intronic
ADediting_1515832chr1_156474386_-intronic
ADediting_1515833chr1_156474423_-intronic
ADediting_1515834chr1_156474427_-intronic
ADediting_1515835chr1_156474442_-intronic
ADediting_1515836chr1_156474614_-intronic
ADediting_1515837chr1_156474682_-intronic
ADediting_1515838chr1_156474788_-intronic
ADediting_1515839chr1_156495589_-intronic
ADediting_1596674chr1_156473195_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_35135chr1_156469318_-SINEAluName=AluSz
ADediting_35136chr1_156469325_-SINEAluName=AluSz
ADediting_35137chr1_156469326_-SINEAluName=AluSz
ADediting_35138chr1_156469343_-SINEAluName=AluSz
ADediting_35139chr1_156469354_-SINEAluName=AluSz
ADediting_35140chr1_156469369_-SINEAluName=AluSz
ADediting_35141chr1_156469379_-SINEAluName=AluSz
ADediting_35142chr1_156469386_-SINEAluName=AluSz
ADediting_35143chr1_156469390_-SINEAluName=AluSz
ADediting_35144chr1_156469395_-SINEAluName=AluSz
ADediting_35145chr1_156469396_-SINEAluName=AluSz
ADediting_35146chr1_156469422_-SINEAluName=AluSz
ADediting_35147chr1_156469426_-SINEAluName=AluSz
ADediting_35148chr1_156469454_-SINEAluName=AluSz
ADediting_35149chr1_156469457_-SINEAluName=AluSz
ADediting_35150chr1_156469471_-SINEAluName=AluSz
ADediting_35151chr1_156469476_-SINEAluName=AluSz
ADediting_35152chr1_156469525_-SINEAluName=AluSz
ADediting_35153chr1_156469530_-SINEAluName=AluSz
ADediting_35154chr1_156469644_-SINEAluName=AluJo
ADediting_35155chr1_156469645_-SINEAluName=AluJo
ADediting_35156chr1_156469671_-SINEAluName=AluJo
ADediting_35157chr1_156469672_-SINEAluName=AluJo
ADediting_35158chr1_156469764_-SINEAluName=AluJo
ADediting_35159chr1_156469773_-SINEAluName=AluJo
ADediting_35160chr1_156469774_-SINEAluName=AluJo
ADediting_35161chr1_156469786_-SINEAluName=AluJo
ADediting_35162chr1_156469799_-SINEAluName=AluJo
ADediting_35163chr1_156469800_-SINEAluName=AluJo
ADediting_35164chr1_156469803_-SINEAluName=AluJo
ADediting_35165chr1_156469810_-SINEAluName=AluJo
ADediting_35166chr1_156469817_-SINEAluName=AluJo
ADediting_35167chr1_156469818_-SINEAluName=AluJo
ADediting_35168chr1_156469824_-SINEAluName=AluJo
ADediting_35169chr1_156469834_-SINEAluName=AluJo
ADediting_35170chr1_156469836_-SINEAluName=AluJo
ADediting_35171chr1_156469842_-SINEAluName=AluJo
ADediting_35172chr1_156469874_-SINEAluName=AluJo
ADediting_35173chr1_156470223_-SINEAluName=AluSx3
ADediting_35174chr1_156470240_-SINEAluName=AluSx3
ADediting_35175chr1_156470254_-SINEAluName=AluSx3
ADediting_35176chr1_156470256_-SINEAluName=AluSx3
ADediting_35177chr1_156470257_-SINEAluName=AluSx3
ADediting_35178chr1_156470263_-SINEAluName=AluSx3
ADediting_35179chr1_156470272_-SINEAluName=AluSx3
ADediting_35180chr1_156470273_-SINEAluName=AluSx3
ADediting_35181chr1_156470295_-SINEAluName=AluSx3
ADediting_35182chr1_156470297_-SINEAluName=AluSx3
ADediting_35183chr1_156470318_-SINEAluName=AluSx3
ADediting_35184chr1_156470319_-SINEAluName=AluSx3
ADediting_35185chr1_156470332_-SINEAluName=AluSx3
ADediting_35186chr1_156470333_-SINEAluName=AluSx3
ADediting_35187chr1_156470337_-SINEAluName=AluSx3
ADediting_35188chr1_156470343_-SINEAluName=AluSx3
ADediting_35189chr1_156470350_-SINEAluName=AluSx3
ADediting_35190chr1_156470357_-SINEAluName=AluSx3
ADediting_35191chr1_156470381_-SINEAluName=AluSx3
ADediting_35192chr1_156470416_-SINEAluName=AluSx3
ADediting_35193chr1_156471093_-SINEAluName=AluSx3
ADediting_35194chr1_156471113_-SINEAluName=AluSx3
ADediting_35195chr1_156471121_-SINEAluName=AluSx3
ADediting_35196chr1_156471131_-SINEAluName=AluSx3
ADediting_35197chr1_156471132_-SINEAluName=AluSx3
ADediting_35198chr1_156471152_-SINEAluName=AluSx3
ADediting_35199chr1_156471161_-SINEAluName=AluSx3
ADediting_35200chr1_156471167_-SINEAluName=AluSx3
ADediting_35201chr1_156471251_-SINEAluName=AluSg
ADediting_35202chr1_156471268_-SINEAluName=AluSg
ADediting_35203chr1_156471269_-SINEAluName=AluSg
ADediting_35204chr1_156471271_-SINEAluName=AluSg
ADediting_35205chr1_156471295_-SINEAluName=AluSg
ADediting_35206chr1_156471301_-SINEAluName=AluSg
ADediting_35207chr1_156471304_-SINEAluName=AluSg
ADediting_35208chr1_156471307_-SINEAluName=AluSg
ADediting_35209chr1_156471324_-SINEAluName=AluSg
ADediting_35210chr1_156471326_-SINEAluName=AluSg
ADediting_35211chr1_156471327_-SINEAluName=AluSg
ADediting_35212chr1_156471344_-SINEAluName=AluSg
ADediting_35213chr1_156471349_-SINEAluName=AluSg
ADediting_35214chr1_156471350_-SINEAluName=AluSg
ADediting_35222chr1_156472559_-SINEAluName=AluSc8
ADediting_35224chr1_156472687_-SINEAluName=AluSc8
ADediting_35225chr1_156472713_-SINEAluName=AluSc8
ADediting_35227chr1_156472777_-SINEAluName=AluSc8
ADediting_35228chr1_156472838_-SINEAluName=AluSc8
ADediting_35229chr1_156472847_-SINEAluName=AluSc8
ADediting_35230chr1_156472848_-SINEAluName=AluSc8
ADediting_35231chr1_156472858_-SINEAluName=AluSc8
ADediting_35233chr1_156472911_-SINEAluName=AluSc8
ADediting_35234chr1_156472998_-SINEAluName=AluSc8
ADediting_35235chr1_156473103_-SINEAluName=AluSc
ADediting_35236chr1_156473135_-SINEAluName=AluSc
ADediting_35237chr1_156473156_-SINEAluName=AluSc
ADediting_35238chr1_156473162_-SINEAluName=AluSc
ADediting_35239chr1_156473166_-SINEAluName=AluSc
ADediting_35240chr1_156473172_-SINEAluName=AluSc
ADediting_35241chr1_156473181_-SINEAluName=AluSc
ADediting_35242chr1_156473182_-SINEAluName=AluSc
ADediting_35243chr1_156473186_-SINEAluName=AluSc
ADediting_35244chr1_156473191_-SINEAluName=AluSc
ADediting_35245chr1_156473200_-SINEAluName=AluSc
ADediting_35246chr1_156473225_-SINEAluName=AluSc
ADediting_35247chr1_156473243_-SINEAluName=AluSc
ADediting_35250chr1_156474200_-SINEAluName=AluSz6
ADediting_35251chr1_156474206_-SINEAluName=AluSz6
ADediting_35252chr1_156474218_-SINEAluName=AluSz6
ADediting_35253chr1_156474246_-SINEAluName=AluSz6
ADediting_35254chr1_156474266_-SINEAluName=AluSz6
ADediting_35255chr1_156474277_-SINEAluName=AluSz6
ADediting_35256chr1_156474283_-SINEAluName=AluSz6
ADediting_35257chr1_156474300_-SINEAluName=AluSz6
ADediting_35258chr1_156474301_-SINEAluName=AluSz6
ADediting_35259chr1_156474321_-SINEAluName=AluSz6
ADediting_35260chr1_156474327_-SINEAluName=AluSz6
ADediting_35261chr1_156474337_-SINEAluName=AluSz6
ADediting_35262chr1_156474349_-SINEAluName=AluSz6
ADediting_35263chr1_156474367_-SINEAluName=AluSz6
ADediting_35264chr1_156474392_-SINEAluName=AluSz6
ADediting_35265chr1_156474405_-SINEAluName=AluSz6
ADediting_35266chr1_156474436_-SINEAluName=AluSz6
ADediting_35267chr1_156474636_-SINEAluName=AluJr
ADediting_35268chr1_156474750_-SINEAluName=AluJr
ADediting_35269chr1_156474758_-SINEAluName=AluJr
ADediting_35270chr1_156474774_-SINEAluName=AluJr
ADediting_35271chr1_156474796_-SINEAluName=AluJr
ADediting_35285chr1_156495572_-SINEAluName=FRAM
ADediting_1515803chr1_156469320_-SINEAluName=AluSz
ADediting_1515804chr1_156469373_-SINEAluName=AluSz
ADediting_1515805chr1_156469382_-SINEAluName=AluSz
ADediting_1515806chr1_156469433_-SINEAluName=AluSz
ADediting_1515807chr1_156469446_-SINEAluName=AluSz
ADediting_1515808chr1_156469462_-SINEAluName=AluSz
ADediting_1515809chr1_156469490_-SINEAluName=AluSz
ADediting_1515810chr1_156469683_-SINEAluName=AluJo
ADediting_1515811chr1_156469722_-SINEAluName=AluJo
ADediting_1515812chr1_156469740_-SINEAluName=AluJo
ADediting_1515813chr1_156469804_-SINEAluName=AluJo
ADediting_1515814chr1_156469869_-SINEAluName=AluJo
ADediting_1515815chr1_156470907_-SINEMIRName=MIRc
ADediting_1515816chr1_156471236_-SINEAluName=AluSg
ADediting_1515817chr1_156471334_-SINEAluName=AluSg
ADediting_1515818chr1_156472601_-SINEAluName=AluSc8
ADediting_1515819chr1_156472982_-SINEAluName=AluSc8
ADediting_1515820chr1_156473129_-SINEAluName=AluSc
ADediting_1515821chr1_156473187_-SINEAluName=AluSc
ADediting_1515822chr1_156473194_-SINEAluName=AluSc
ADediting_1515823chr1_156473197_-SINEAluName=AluSc
ADediting_1515824chr1_156473206_-SINEAluName=AluSc
ADediting_1515825chr1_156473287_-SINEAluName=AluSc
ADediting_1515826chr1_156473294_-SINEAluName=AluSc
ADediting_1515827chr1_156474244_-SINEAluName=AluSz6
ADediting_1515828chr1_156474245_-SINEAluName=AluSz6
ADediting_1515829chr1_156474286_-SINEAluName=AluSz6
ADediting_1515830chr1_156474325_-SINEAluName=AluSz6
ADediting_1515831chr1_156474356_-SINEAluName=AluSz6
ADediting_1515832chr1_156474386_-SINEAluName=AluSz6
ADediting_1515833chr1_156474423_-SINEAluName=AluSz6
ADediting_1515834chr1_156474427_-SINEAluName=AluSz6
ADediting_1515835chr1_156474442_-SINEAluName=AluSz6
ADediting_1515836chr1_156474614_-SINEAluName=AluJr
ADediting_1515837chr1_156474682_-SINEAluName=AluJr
ADediting_1515838chr1_156474788_-SINEAluName=AluJr
ADediting_1515839chr1_156495589_-SINEAluName=FRAM
ADediting_1596674chr1_156473195_-SINEAluName=AluSc

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RNA A-to-I editing events in the alternative splicing sites for MEF2D

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for MEF2D

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for MEF2D

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for MEF2D


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1391023chr8_140732605_-ENSG00000116604.18ENST00000348159.9MEF2D-201hsa-miR-151a-3pchr11564663181564663247mer-m8156466317156466338150-20.48
ADediting_1391023chr8_140732605_-ENSG00000116604.18ENST00000360595.7MEF2D-202hsa-miR-151a-3pchr11564663181564663247mer-m8156466317156466338150-20.48
ADediting_1391023chr8_140732605_-ENSG00000116604.18ENST00000368240.6MEF2D-203hsa-miR-151a-3pchr11564663181564663247mer-m8156466317156466338150-20.48
ADediting_1391023chr8_140732605_-ENSG00000116604.18ENST00000464356.6MEF2D-204hsa-miR-151a-3pchr11564663181564663247mer-m8156466317156466338150-20.48
ADediting_1535954chr14_101045974_+ENSG00000116604.18ENST00000368240.6MEF2D-203hsa-miR-381-3pchr11564687961564688027mer-m8156468795156468816160-17.67
ADediting_496066chr15_66496985_-ENSG00000116604.18ENST00000348159.9MEF2D-201hsa-miR-4512chr11564660491564660557mer-m8156466048156466070145-20.33
ADediting_496066chr15_66496985_-ENSG00000116604.18ENST00000464356.6MEF2D-204hsa-miR-4512chr11564660491564660557mer-m8156466048156466070145-20.33

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1556067chr19_40282625_-ENSG00000116604.18ENST00000348159.9MEF2D-201hsa-miR-641chr11564645971564646037mer-m8156464596156464620142-15.79
ADediting_1556067chr19_40282625_-ENSG00000116604.18ENST00000464356.6MEF2D-204hsa-miR-641chr11564645971564646037mer-m8156464596156464620142-15.79
ADediting_1631458chr19_40282624_-ENSG00000116604.18ENST00000348159.9MEF2D-201hsa-miR-641chr11564645971564646037mer-m8156464596156464620142-15.79
ADediting_1631458chr19_40282624_-ENSG00000116604.18ENST00000464356.6MEF2D-204hsa-miR-641chr11564645971564646037mer-m8156464596156464620142-15.79

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for MEF2D

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for MEF2D

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
CERADediting_1515829chr1_156474286_-0.0001215417187687670.308664349545290.0002306778144539950.2963940282035130.636474045497609-0.0389012499219583
DLPFCADediting_35136chr1_156469325_-0.004086162680002130.1626560565371830.492575181414370.03911771135152518.37402129219666e-100.339556521761866
TCXADediting_35136chr1_156469325_-0.3945068087062560.07002284183936360.0451274607106797-0.1638456337239571.54877918583011e-060.380627744701241
DLPFCADediting_35137chr1_156469326_-0.008404151244102230.1494421729400630.8151538158252660.01333122006139532.11349187925655e-080.311504092482473
DLPFCADediting_35144chr1_156469395_-2.3233926822158e-060.2645260777241010.08641261946358370.09754627838168735.62996562910366e-160.43818887968559
DLPFCADediting_35149chr1_156469457_-0.0002719349202458410.2053967116417150.117270841450440.08914462129343235.03455635056411e-130.395097918034522
CERADediting_35156chr1_156469671_-0.0001645504867061790.3029302813971461.48717927286851e-050.3455278724640870.0238156581392460.184491906496419
DLPFCADediting_35158chr1_156469764_-0.0006127471171508140.1935177798817050.2422443912239370.06661249764038019.72237099156571e-190.473630480872151
DLPFCADediting_35160chr1_156469774_-0.0009702734398198840.1864781619420890.1286997015054840.08647520269105523.25192330329232e-150.427645532533946
DLPFCADediting_35161chr1_156469786_-0.0001059907414333140.2183866067189170.08306940078044210.09859451089148436.75893815057017e-160.437107081478658
TCXADediting_35161chr1_156469786_-0.9332951032619250.006891632129346060.0257904059967637-0.1820251989805557.9398435617152e-070.390255694728005
DLPFCADediting_35169chr1_156469834_-4.73408934996604e-050.2289176628656030.08461851245246830.09810465958674622.4356773783423e-140.415068263575423
DLPFCADediting_35173chr1_156470223_-0.07088589696514540.1027291420027960.173931215603928-0.0774214408281095.05809365400788e-130.39506610763911
CERADediting_35173chr1_156470223_-5.16231414087287e-050.3242666845562850.0007670585723915710.27178730899190.9225289513851180.00800717389457772
DLPFCADediting_35174chr1_156470240_-0.01693476131765270.1355571355804370.873195421912531-0.009101304791978416.47291608995165e-080.301060390196261
DLPFCADediting_35176chr1_156470256_-0.001639538231541750.1781259181880790.3014249948621030.05887909896466962.72552562720779e-130.399253691278094
DLPFCADediting_35177chr1_156470257_-0.001979727752872770.1750340674765770.6038871288444470.02957997287038611.18888295002663e-210.507011637585917
DLPFCADediting_35204chr1_156471271_-0.007240397439395580.1522555122491450.3350417969726180.05493255070042186.55236045099553e-120.377058059395138
DLPFCADediting_35205chr1_156471295_-0.001736865093925410.1771855334161970.4986165915272240.03857368510556082.53013423503021e-200.492243172662696
TCXADediting_35205chr1_156471295_-0.188814539412620.1078843936494020.430142684004349-0.06489221335290357.49423960235251e-050.317580191577205
DLPFCADediting_35211chr1_156471327_-0.01663853202200510.135921451670330.8504347690268960.01075282889586551.65332425686043e-170.458350487745377
DLPFCADediting_35227chr1_156472777_-0.643643786541292-0.02637647714620850.0233091189925955-0.1288156545523672.31909325855731e-110.367746858622623
CERADediting_35237chr1_156473156_-0.0006539593017344410.2751867276465220.0001816338076447520.3010349691898820.3593613254341910.0753626156260871
DLPFCADediting_35254chr1_156474266_-0.001122784022753970.1841892759190560.1137656758491770.09000389414153565.90246806422689e-120.377814419174049
DLPFCADediting_35255chr1_156474277_-0.0265910964770520.1259506098453720.5691298588018160.03245857106310541.90690274669582e-080.312443743645718
DLPFCADediting_35258chr1_156474301_-0.06845440485410910.1036227330604630.581735694144661-0.03140539647061422.01625533970245e-250.545400338104621
TCXADediting_35258chr1_156474301_-0.5454857101454070.04974593092831360.0427626818723044-0.1656648765332499.97126881520582e-070.387007222973094
DLPFCADediting_35265chr1_156474405_-0.004913807790576530.1593682725777270.1820647488682220.07598757514097016.03108523445835e-080.301732323477085
DLPFCADediting_35266chr1_156474436_-0.00168648695854870.1776660928705630.1498372437006880.08198600814676392.23522294796416e-140.415615580650694
TCXADediting_35266chr1_156474436_-0.2921316328336990.08657702963923840.24825629367843-0.09485306090256324.06509729409654e-060.366156636065188
CERADediting_35269chr1_156474758_-0.0003367383472170490.2888854221897611.0451093567679e-050.3512825126787260.202938708439110.104547721752899
CERADediting_35270chr1_156474774_-0.001006137684667990.2659031334707715.9723060702521e-050.3216708643598570.1780683809980060.110547187387928
TCXADediting_35272chr1_156475821_-0.09392327407929790.1372678487931920.596334319991195-0.0435922335359494.39586976700132e-050.327102096940647

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC1.8575273445845e-690.797139677005822.2483302319572e-770.8222326067693645.34231368517011e-050.227369640960067
AC1.49359110507638e-290.6343508068855311.23705798370023e-320.6598965661716150.214388979472462-0.0787976007949189
PCC5.279518273974e-530.8439086679219061.72148319768086e-500.833094437194530.6230553113622020.0357890192321986
CER1.1480500180062e-350.8069587804619035.12595333433384e-370.815772909699560.09602525356560990.136405780102021
TCX4.90567321222529e-380.8221271363475464.29919612071962e-390.8284627472014210.305964254506783-0.0841425124065943
FP2.40646175406408e-180.5938348180130175.36085137319574e-050.2979528328326122.90472830719577e-060.3423486192102
IFG7.18183238522866e-100.9022260019856917.45522545116587e-070.8139402682181860.1192812947870030.319685582165525
STG4.1458682548698e-140.7096321685876256.97288266780334e-050.4199951510629190.1099193661580580.175689639344176

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Relation with AD stages for MEF2D

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
CERADediting_35270chr1_156474774_-0.001556507816354410.30086436881278
CERADediting_1515805chr1_156469382_-0.0007239279308700590.320384251342127
TCXADediting_35263chr1_156474367_-0.001327230163489370.307827887729012
TCXADediting_35266chr1_156474436_-0.0001101480303711230.366775204255149

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.

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RelatedDrugs for MEF2D

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for MEF2D

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource
MEF2DC0338480Common Migraine1CTD_human