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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for LAMP2 |
 Gene summary |
| Gene information | Gene symbol | LAMP2 | Gene ID | 3920 |
| Gene name | lysosomal associated membrane protein 2 | |
| Synonyms | CD107b|DND|LAMP-2|LAMPB|LGP-96|LGP110 | |
| Cytomap | Xq24 | |
| Type of gene | protein-coding | |
| Description | lysosome-associated membrane glycoprotein 2CD107 antigen-like family member B | |
| Modification date | 20200321 | |
| UniProtAcc | P13473, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for LAMP2 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_1488884(120434862, -), ADediting_1488885(120434866, -), ADediting_1488886(120434911, -), ADediting_1488887(120434912, -), ADediting_1488888(120434937, -), ADediting_1488889(120434963, -), ADediting_1488890(120434966, -), ADediting_1488891(120434974, -), ADediting_1488892(120434990, -), ADediting_1488893(120435006, -), ADediting_1488894(120435008, -), ADediting_1488895(120435018, -), ADediting_1488896(120435022, -), ADediting_1488897(120435030, -), ADediting_1488898(120435043, -), ADediting_1488899(120435044, -), ADediting_1488900(120435047, -), ADediting_1488901(120435048, -), ADediting_1488902(120435054, -), ADediting_1488903(120435067, -), ADediting_1488904(120435068, -), ADediting_1488905(120435073, -), ADediting_1488906(120435078, -), ADediting_1488907(120435126, -), ADediting_1488908(120435130, -), ADediting_1488909(120437883, -), ADediting_1488910(120437923, -), ADediting_1488911(120437924, -), ADediting_1488912(120437941, -), ADediting_1488913(120437952, -), ADediting_1488914(120437958, -), ADediting_1488915(120437961, -), ADediting_1488916(120437984, -), ADediting_1488917(120437988, -), ADediting_1488918(120437993, -), ADediting_1488919(120437994, -), ADediting_1488920(120438027, -), ADediting_1488921(120438061, -), ADediting_1488922(120438070, -), ADediting_1488923(120438073, -), ADediting_1488924(120438075, -), ADediting_1488925(120438084, -), ADediting_1488926(120438094, -), ADediting_1488927(120438106, -), ADediting_1488928(120438129, -), ADediting_1488929(120438130, -), ADediting_1488930(120451065, -), ADediting_1488931(120451533, -), ADediting_1488932(120451570, -), ADediting_1488933(120451579, -), ADediting_1488934(120451581, -), ADediting_1488935(120451593, -), ADediting_1488936(120451602, -), ADediting_1488937(120451603, -), ADediting_1488938(120451619, -), ADediting_1488939(120451693, -), ADediting_1488940(120452605, -), ADediting_1488941(120452611, -), ADediting_1488942(120452643, -), ADediting_1488943(120452648, -), ADediting_1488944(120452666, -), ADediting_1488945(120452773, -), ADediting_1488946(120452840, -), ADediting_1488947(120453553, -), ADediting_1488948(120453565, -), ADediting_1488949(120453642, -), ADediting_1488950(120453691, -), ADediting_1488951(120453696, -), ADediting_1488952(120453708, -), ADediting_1488953(120453722, -), ADediting_1488954(120453745, -), ADediting_1488955(120460157, -), ADediting_1488956(120460725, -), ADediting_1488957(120460759, -), ADediting_1488958(120460807, -), ADediting_1488959(120460839, -), ADediting_1488960(120460851, -), ADediting_1488961(120462270, -), ADediting_1488962(120462303, -), ADediting_1488963(120462390, -), ADediting_1488964(120462459, -), ADediting_1488965(120462460, -), ADediting_1488966(120462484, -), ADediting_1488967(120466910, -), ADediting_1488968(120466981, -), ADediting_1488969(120466991, -), ADediting_1488970(120467982, -), ADediting_1594788(120439774, -), ADediting_1674567(120434961, -), ADediting_1674568(120437882, -), ADediting_1674569(120437884, -), ADediting_1674570(120437887, -), ADediting_1674571(120437889, -), ADediting_1674572(120437916, -), ADediting_1674573(120437945, -), ADediting_1674574(120437967, -), ADediting_1674575(120438020, -), ADediting_1674576(120438050, -), ADediting_1674577(120438060, -), ADediting_1674578(120451024, -), ADediting_1674579(120462277, -), ADediting_1674580(120462405, -), ADediting_1674581(120464890, -), ADediting_1674582(120464951, -), |
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RNA editing positional annotations for LAMP2 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_1488884 | chrX_120434862_- | intronic |
| ADediting_1488885 | chrX_120434866_- | intronic |
| ADediting_1488886 | chrX_120434911_- | intronic |
| ADediting_1488887 | chrX_120434912_- | intronic |
| ADediting_1488888 | chrX_120434937_- | intronic |
| ADediting_1488889 | chrX_120434963_- | intronic |
| ADediting_1488890 | chrX_120434966_- | intronic |
| ADediting_1488891 | chrX_120434974_- | intronic |
| ADediting_1488892 | chrX_120434990_- | intronic |
| ADediting_1488893 | chrX_120435006_- | intronic |
| ADediting_1488894 | chrX_120435008_- | intronic |
| ADediting_1488895 | chrX_120435018_- | intronic |
| ADediting_1488896 | chrX_120435022_- | intronic |
| ADediting_1488897 | chrX_120435030_- | intronic |
| ADediting_1488898 | chrX_120435043_- | intronic |
| ADediting_1488899 | chrX_120435044_- | intronic |
| ADediting_1488900 | chrX_120435047_- | intronic |
| ADediting_1488901 | chrX_120435048_- | intronic |
| ADediting_1488902 | chrX_120435054_- | intronic |
| ADediting_1488903 | chrX_120435067_- | intronic |
| ADediting_1488904 | chrX_120435068_- | intronic |
| ADediting_1488905 | chrX_120435073_- | intronic |
| ADediting_1488906 | chrX_120435078_- | intronic |
| ADediting_1488907 | chrX_120435126_- | intronic |
| ADediting_1488908 | chrX_120435130_- | intronic |
| ADediting_1488909 | chrX_120437883_- | UTR3 |
| ADediting_1488910 | chrX_120437923_- | UTR3 |
| ADediting_1488911 | chrX_120437924_- | UTR3 |
| ADediting_1488912 | chrX_120437941_- | UTR3 |
| ADediting_1488913 | chrX_120437952_- | UTR3 |
| ADediting_1488914 | chrX_120437958_- | UTR3 |
| ADediting_1488915 | chrX_120437961_- | UTR3 |
| ADediting_1488916 | chrX_120437984_- | UTR3 |
| ADediting_1488917 | chrX_120437988_- | UTR3 |
| ADediting_1488918 | chrX_120437993_- | UTR3 |
| ADediting_1488919 | chrX_120437994_- | UTR3 |
| ADediting_1488920 | chrX_120438027_- | UTR3 |
| ADediting_1488921 | chrX_120438061_- | UTR3 |
| ADediting_1488922 | chrX_120438070_- | UTR3 |
| ADediting_1488923 | chrX_120438073_- | UTR3 |
| ADediting_1488924 | chrX_120438075_- | UTR3 |
| ADediting_1488925 | chrX_120438084_- | UTR3 |
| ADediting_1488926 | chrX_120438094_- | UTR3 |
| ADediting_1488927 | chrX_120438106_- | UTR3 |
| ADediting_1488928 | chrX_120438129_- | UTR3 |
| ADediting_1488929 | chrX_120438130_- | UTR3 |
| ADediting_1488930 | chrX_120451065_- | intronic |
| ADediting_1488931 | chrX_120451533_- | intronic |
| ADediting_1488932 | chrX_120451570_- | intronic |
| ADediting_1488933 | chrX_120451579_- | intronic |
| ADediting_1488934 | chrX_120451581_- | intronic |
| ADediting_1488935 | chrX_120451593_- | intronic |
| ADediting_1488936 | chrX_120451602_- | intronic |
| ADediting_1488937 | chrX_120451603_- | intronic |
| ADediting_1488938 | chrX_120451619_- | intronic |
| ADediting_1488939 | chrX_120451693_- | intronic |
| ADediting_1488940 | chrX_120452605_- | intronic |
| ADediting_1488941 | chrX_120452611_- | intronic |
| ADediting_1488942 | chrX_120452643_- | intronic |
| ADediting_1488943 | chrX_120452648_- | intronic |
| ADediting_1488944 | chrX_120452666_- | intronic |
| ADediting_1488945 | chrX_120452773_- | intronic |
| ADediting_1488946 | chrX_120452840_- | intronic |
| ADediting_1488947 | chrX_120453553_- | intronic |
| ADediting_1488948 | chrX_120453565_- | intronic |
| ADediting_1488949 | chrX_120453642_- | intronic |
| ADediting_1488950 | chrX_120453691_- | intronic |
| ADediting_1488951 | chrX_120453696_- | intronic |
| ADediting_1488952 | chrX_120453708_- | intronic |
| ADediting_1488953 | chrX_120453722_- | intronic |
| ADediting_1488954 | chrX_120453745_- | intronic |
| ADediting_1488955 | chrX_120460157_- | intronic |
| ADediting_1488956 | chrX_120460725_- | intronic |
| ADediting_1488957 | chrX_120460759_- | intronic |
| ADediting_1488958 | chrX_120460807_- | intronic |
| ADediting_1488959 | chrX_120460839_- | intronic |
| ADediting_1488960 | chrX_120460851_- | intronic |
| ADediting_1488961 | chrX_120462270_- | intronic |
| ADediting_1488962 | chrX_120462303_- | intronic |
| ADediting_1488963 | chrX_120462390_- | intronic |
| ADediting_1488964 | chrX_120462459_- | intronic |
| ADediting_1488965 | chrX_120462460_- | intronic |
| ADediting_1488966 | chrX_120462484_- | intronic |
| ADediting_1488967 | chrX_120466910_- | intronic |
| ADediting_1488968 | chrX_120466981_- | intronic |
| ADediting_1488969 | chrX_120466991_- | intronic |
| ADediting_1488970 | chrX_120467982_- | intronic |
| ADediting_1594788 | chrX_120439774_- | intronic |
| ADediting_1674567 | chrX_120434961_- | intronic |
| ADediting_1674568 | chrX_120437882_- | UTR3 |
| ADediting_1674569 | chrX_120437884_- | UTR3 |
| ADediting_1674570 | chrX_120437887_- | UTR3 |
| ADediting_1674571 | chrX_120437889_- | UTR3 |
| ADediting_1674572 | chrX_120437916_- | UTR3 |
| ADediting_1674573 | chrX_120437945_- | UTR3 |
| ADediting_1674574 | chrX_120437967_- | UTR3 |
| ADediting_1674575 | chrX_120438020_- | UTR3 |
| ADediting_1674576 | chrX_120438050_- | UTR3 |
| ADediting_1674577 | chrX_120438060_- | UTR3 |
| ADediting_1674578 | chrX_120451024_- | intronic |
| ADediting_1674579 | chrX_120462277_- | intronic |
| ADediting_1674580 | chrX_120462405_- | intronic |
| ADediting_1674581 | chrX_120464890_- | intronic |
| ADediting_1674582 | chrX_120464951_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_1488884 | chrX_120434862_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488885 | chrX_120434866_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488886 | chrX_120434911_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488887 | chrX_120434912_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488888 | chrX_120434937_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488889 | chrX_120434963_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488890 | chrX_120434966_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488891 | chrX_120434974_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488892 | chrX_120434990_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488893 | chrX_120435006_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488894 | chrX_120435008_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488895 | chrX_120435018_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488896 | chrX_120435022_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488897 | chrX_120435030_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488898 | chrX_120435043_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488899 | chrX_120435044_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488900 | chrX_120435047_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488901 | chrX_120435048_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488902 | chrX_120435054_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488903 | chrX_120435067_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488904 | chrX_120435068_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488905 | chrX_120435073_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488906 | chrX_120435078_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488907 | chrX_120435126_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488908 | chrX_120435130_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488909 | chrX_120437883_- | SINE | Alu | Name=AluSq2 |
| ADediting_1488910 | chrX_120437923_- | SINE | Alu | Name=AluSq2 |
| ADediting_1488911 | chrX_120437924_- | SINE | Alu | Name=AluSq2 |
| ADediting_1488912 | chrX_120437941_- | SINE | Alu | Name=AluSq2 |
| ADediting_1488913 | chrX_120437952_- | SINE | Alu | Name=AluSq2 |
| ADediting_1488914 | chrX_120437958_- | SINE | Alu | Name=AluSq2 |
| ADediting_1488915 | chrX_120437961_- | SINE | Alu | Name=AluSq2 |
| ADediting_1488916 | chrX_120437984_- | SINE | Alu | Name=AluSq2 |
| ADediting_1488917 | chrX_120437988_- | SINE | Alu | Name=AluSq2 |
| ADediting_1488918 | chrX_120437993_- | SINE | Alu | Name=AluSq2 |
| ADediting_1488919 | chrX_120437994_- | SINE | Alu | Name=AluSq2 |
| ADediting_1488920 | chrX_120438027_- | SINE | Alu | Name=AluSq2 |
| ADediting_1488921 | chrX_120438061_- | SINE | Alu | Name=AluSq2 |
| ADediting_1488922 | chrX_120438070_- | SINE | Alu | Name=AluSq2 |
| ADediting_1488923 | chrX_120438073_- | SINE | Alu | Name=AluSq2 |
| ADediting_1488924 | chrX_120438075_- | SINE | Alu | Name=AluSq2 |
| ADediting_1488925 | chrX_120438084_- | SINE | Alu | Name=AluSq2 |
| ADediting_1488926 | chrX_120438094_- | SINE | Alu | Name=AluSq2 |
| ADediting_1488927 | chrX_120438106_- | SINE | Alu | Name=AluSq2 |
| ADediting_1488928 | chrX_120438129_- | SINE | Alu | Name=AluSq2 |
| ADediting_1488929 | chrX_120438130_- | SINE | Alu | Name=AluSq2 |
| ADediting_1488930 | chrX_120451065_- | SINE | Alu | Name=AluSx |
| ADediting_1488931 | chrX_120451533_- | SINE | Alu | Name=AluSz |
| ADediting_1488932 | chrX_120451570_- | SINE | Alu | Name=AluSz |
| ADediting_1488933 | chrX_120451579_- | SINE | Alu | Name=AluSz |
| ADediting_1488934 | chrX_120451581_- | SINE | Alu | Name=AluSz |
| ADediting_1488935 | chrX_120451593_- | SINE | Alu | Name=AluSz |
| ADediting_1488936 | chrX_120451602_- | SINE | Alu | Name=AluSz |
| ADediting_1488937 | chrX_120451603_- | SINE | Alu | Name=AluSz |
| ADediting_1488938 | chrX_120451619_- | SINE | Alu | Name=AluSz |
| ADediting_1488939 | chrX_120451693_- | SINE | Alu | Name=AluSz |
| ADediting_1488940 | chrX_120452605_- | SINE | Alu | Name=AluJb |
| ADediting_1488941 | chrX_120452611_- | SINE | Alu | Name=AluJb |
| ADediting_1488942 | chrX_120452643_- | SINE | Alu | Name=AluJb |
| ADediting_1488943 | chrX_120452648_- | SINE | Alu | Name=AluJb |
| ADediting_1488944 | chrX_120452666_- | SINE | Alu | Name=AluJb |
| ADediting_1488945 | chrX_120452773_- | SINE | Alu | Name=AluJb |
| ADediting_1488946 | chrX_120452840_- | SINE | Alu | Name=AluJb |
| ADediting_1488947 | chrX_120453553_- | SINE | Alu | Name=AluSg |
| ADediting_1488948 | chrX_120453565_- | SINE | Alu | Name=AluSg |
| ADediting_1488949 | chrX_120453642_- | SINE | Alu | Name=AluSg |
| ADediting_1488950 | chrX_120453691_- | SINE | Alu | Name=AluSg |
| ADediting_1488951 | chrX_120453696_- | SINE | Alu | Name=AluSg |
| ADediting_1488952 | chrX_120453708_- | SINE | Alu | Name=AluSg |
| ADediting_1488953 | chrX_120453722_- | SINE | Alu | Name=AluSg |
| ADediting_1488954 | chrX_120453745_- | SINE | Alu | Name=AluSg |
| ADediting_1488955 | chrX_120460157_- | SINE | Alu | Name=AluSx1 |
| ADediting_1488956 | chrX_120460725_- | SINE | Alu | Name=AluSq |
| ADediting_1488957 | chrX_120460759_- | SINE | Alu | Name=AluSq |
| ADediting_1488958 | chrX_120460807_- | SINE | Alu | Name=AluSq |
| ADediting_1488959 | chrX_120460839_- | SINE | Alu | Name=AluSq |
| ADediting_1488960 | chrX_120460851_- | SINE | Alu | Name=AluSq |
| ADediting_1488961 | chrX_120462270_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488962 | chrX_120462303_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488963 | chrX_120462390_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488964 | chrX_120462459_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488965 | chrX_120462460_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488966 | chrX_120462484_- | SINE | Alu | Name=AluSz6 |
| ADediting_1488967 | chrX_120466910_- | SINE | Alu | Name=AluSq |
| ADediting_1488968 | chrX_120466981_- | SINE | Alu | Name=AluSq |
| ADediting_1488969 | chrX_120466991_- | SINE | Alu | Name=AluSq |
| ADediting_1488970 | chrX_120467982_- | SINE | Alu | Name=AluSq2 |
| ADediting_1674567 | chrX_120434961_- | SINE | Alu | Name=AluSz6 |
| ADediting_1674568 | chrX_120437882_- | SINE | Alu | Name=AluSq2 |
| ADediting_1674569 | chrX_120437884_- | SINE | Alu | Name=AluSq2 |
| ADediting_1674570 | chrX_120437887_- | SINE | Alu | Name=AluSq2 |
| ADediting_1674571 | chrX_120437889_- | SINE | Alu | Name=AluSq2 |
| ADediting_1674572 | chrX_120437916_- | SINE | Alu | Name=AluSq2 |
| ADediting_1674573 | chrX_120437945_- | SINE | Alu | Name=AluSq2 |
| ADediting_1674574 | chrX_120437967_- | SINE | Alu | Name=AluSq2 |
| ADediting_1674575 | chrX_120438020_- | SINE | Alu | Name=AluSq2 |
| ADediting_1674576 | chrX_120438050_- | SINE | Alu | Name=AluSq2 |
| ADediting_1674577 | chrX_120438060_- | SINE | Alu | Name=AluSq2 |
| ADediting_1674578 | chrX_120451024_- | SINE | Alu | Name=AluSx |
| ADediting_1674579 | chrX_120462277_- | SINE | Alu | Name=AluSz6 |
| ADediting_1674580 | chrX_120462405_- | SINE | Alu | Name=AluSz6 |
| ADediting_1674581 | chrX_120464890_- | SINE | Alu | Name=AluSq2 |
| ADediting_1674582 | chrX_120464951_- | SINE | Alu | Name=AluSq2 |
Top |
RNA A-to-I editing events in the alternative splicing sites for LAMP2 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| A3SS | ADediting_1488908 | chrX_120435130_- | 120435128:120435150 | 3ss | 1e | TTTGTTTTGTTTTGTTTGAGATG | 3.86 | TTTGTTTTGTTTTGTTTGAGGTG | 5.52 |
| ES | ADediting_1488908 | chrX_120435130_- | 120435128:120435150 | 3ss | 1e | TTTGTTTTGTTTTGTTTGAGATG | 3.86 | TTTGTTTTGTTTTGTTTGAGGTG | 5.52 |
| ES | ADediting_1488900 | chrX_120435047_- | 120435047:120435055 | 5ss | 6i | CAGGTTCAA | 1.19 | CAGGTTCAG | 2.78 |
| ES | ADediting_1488900 | chrX_120435047_- | 120435047:120435055 | 5ss | 6i | CAGGTTCAA | 1.19 | CAGGTTCAG | 2.78 |
| ES | ADediting_1488900 | chrX_120435047_- | 120435047:120435055 | 5ss | 6i | CAGGTTCAA | 1.19 | CAGGTTCAG | 2.78 |
| ES | ADediting_1488901 | chrX_120435048_- | 120435047:120435055 | 5ss | 5i | CAGGTTCAA | 1.19 | CAGGTTCGA | 5.36 |
| ES | ADediting_1488901 | chrX_120435048_- | 120435047:120435055 | 5ss | 5i | CAGGTTCAA | 1.19 | CAGGTTCGA | 5.36 |
| ES | ADediting_1488902 | chrX_120435054_- | 120435047:120435055 | 5ss | 2e | CAGGTTCAA | 1.19 | CGGGTTCAA | -6.26 |
| ES | ADediting_1488902 | chrX_120435054_- | 120435047:120435055 | 5ss | 2e | CAGGTTCAA | 1.19 | CGGGTTCAA | -6.26 |
| ES | ADediting_1488902 | chrX_120435054_- | 120435047:120435055 | 5ss | 2e | CAGGTTCAA | 1.19 | CGGGTTCAA | -6.26 |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for LAMP2 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for LAMP2 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for LAMP2 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1488909 | chrX_120437883_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-4294 | chrX | 120437877 | 120437884 | 8mer-1a | 120437877 | 120437893 | 140 | -13.02 |
| ADediting_1488910 | chrX_120437923_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-149-5p | chrX | 120437923 | 120437929 | 7mer-m8 | 120437922 | 120437946 | 152 | -25.3 |
| ADediting_1488911 | chrX_120437924_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-4638-5p | chrX | 120437921 | 120437928 | 8mer-1a | 120437921 | 120437942 | 144 | -20.6 |
| ADediting_1488912 | chrX_120437941_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-1281 | chrX | 120437941 | 120437947 | 7mer-m8 | 120437940 | 120437956 | 141 | -16.88 |
| ADediting_1488913 | chrX_120437952_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-4437 | chrX | 120437949 | 120437955 | 7mer-m8 | 120437948 | 120437968 | 146 | -19.54 |
| ADediting_1488919 | chrX_120437994_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-513a-5p | chrX | 120437993 | 120437999 | 7mer-m8 | 120437992 | 120438009 | 140 | -14.76 |
| ADediting_1488919 | chrX_120437994_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-638 | chrX | 120437988 | 120437994 | 7mer-1a | 120437988 | 120438012 | 151 | -32.44 |
| ADediting_1488920 | chrX_120438027_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-4742-3p | chrX | 120438026 | 120438033 | 8mer-1a | 120438026 | 120438049 | 141 | -10.15 |
| ADediting_1488923 | chrX_120438073_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-3176 | chrX | 120438069 | 120438075 | 7mer-m8 | 120438068 | 120438086 | 156 | -24.97 |
| ADediting_1488923 | chrX_120438073_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-3922-3p | chrX | 120438069 | 120438075 | 7mer-m8 | 120438068 | 120438089 | 150 | -20.02 |
| ADediting_1488923 | chrX_120438073_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-6878-3p | chrX | 120438070 | 120438076 | 7mer-m8 | 120438069 | 120438091 | 150 | -25.27 |
| ADediting_1488927 | chrX_120438106_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-1224-3p | chrX | 120438101 | 120438107 | 7mer-m8 | 120438100 | 120438119 | 156 | -26.28 |
| ADediting_1488928 | chrX_120438129_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-8052 | chrX | 120438124 | 120438130 | 7mer-1a | 120438124 | 120438142 | 140 | -24.15 |
| ADediting_1488929 | chrX_120438130_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-513a-5p | chrX | 120438129 | 120438135 | 7mer-m8 | 120438128 | 120438148 | 147 | -22.37 |
| ADediting_1488929 | chrX_120438130_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-638 | chrX | 120438124 | 120438130 | 7mer-1a | 120438124 | 120438148 | 163 | -37.94 |
| ADediting_1674568 | chrX_120437882_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-6874-5p | chrX | 120437877 | 120437883 | 7mer-m8 | 120437876 | 120437898 | 140 | -15.64 |
| ADediting_1674569 | chrX_120437884_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-1468-5p | chrX | 120437882 | 120437889 | 8mer-1a | 120437882 | 120437900 | 144 | -15.07 |
| ADediting_1674570 | chrX_120437887_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-3140-3p | chrX | 120437886 | 120437892 | 7mer-m8 | 120437885 | 120437905 | 145 | -17.85 |
| ADediting_1674570 | chrX_120437887_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-4790-5p | chrX | 120437883 | 120437890 | 8mer-1a | 120437883 | 120437903 | 141 | -12.16 |
| ADediting_1674571 | chrX_120437889_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-3655 | chrX | 120437888 | 120437895 | 8mer-1a | 120437888 | 120437906 | 155 | -23.97 |
| ADediting_1674571 | chrX_120437889_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-578 | chrX | 120437887 | 120437893 | 7mer-m8 | 120437886 | 120437906 | 158 | -18.63 |
| ADediting_1674572 | chrX_120437916_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-652-3p | chrX | 120437912 | 120437918 | 7mer-m8 | 120437911 | 120437932 | 154 | -19.49 |
| ADediting_1674573 | chrX_120437945_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-1913 | chrX | 120437939 | 120437946 | 8mer-1a | 120437939 | 120437960 | 147 | -21.42 |
| ADediting_1674573 | chrX_120437945_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-4313 | chrX | 120437941 | 120437947 | 7mer-1a | 120437941 | 120437960 | 140 | -21.04 |
| ADediting_1674573 | chrX_120437945_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-5587-3p | chrX | 120437945 | 120437951 | 7mer-m8 | 120437944 | 120437965 | 154 | -25.39 |
| ADediting_1674573 | chrX_120437945_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-6840-5p | chrX | 120437944 | 120437950 | 7mer-m8 | 120437943 | 120437973 | 149 | -32 |
| ADediting_1674576 | chrX_120438050_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-412-3p | chrX | 120438050 | 120438056 | 7mer-m8 | 120438049 | 120438071 | 153 | -17.3 |
| ADediting_1674576 | chrX_120438050_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-6754-3p | chrX | 120438050 | 120438056 | 7mer-m8 | 120438049 | 120438069 | 144 | -15.76 |
| ADediting_1674577 | chrX_120438060_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-3190-5p | chrX | 120438060 | 120438066 | 7mer-m8 | 120438059 | 120438078 | 154 | -19.64 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1488910 | chrX_120437923_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-6812-3p | chrX | 120437918 | 120437924 | 7mer-m8 | 120437917 | 120437936 | 149 | -18.53 |
| ADediting_1488912 | chrX_120437941_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-6836-3p | chrX | 120437941 | 120437947 | 7mer-m8 | 120437940 | 120437960 | 145 | -19.03 |
| ADediting_1488914 | chrX_120437958_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-8062 | chrX | 120437956 | 120437962 | 7mer-m8 | 120437955 | 120437975 | 141 | -10.43 |
| ADediting_1488915 | chrX_120437961_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-8062 | chrX | 120437956 | 120437962 | 7mer-m8 | 120437955 | 120437975 | 141 | -10.43 |
| ADediting_1488917 | chrX_120437988_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-5089-5p | chrX | 120437988 | 120437994 | 7mer-m8 | 120437987 | 120438007 | 144 | -13.27 |
| ADediting_1488917 | chrX_120437988_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-6506-5p | chrX | 120437987 | 120437993 | 7mer-m8 | 120437986 | 120438008 | 144 | -16.5 |
| ADediting_1488918 | chrX_120437993_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-10399-5p | chrX | 120437992 | 120437998 | 7mer-m8 | 120437991 | 120438010 | 141 | -11.84 |
| ADediting_1488918 | chrX_120437993_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-5089-5p | chrX | 120437988 | 120437994 | 7mer-m8 | 120437987 | 120438007 | 144 | -13.27 |
| ADediting_1488918 | chrX_120437993_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-6504-3p | chrX | 120437992 | 120437998 | 7mer-m8 | 120437991 | 120438009 | 144 | -11.8 |
| ADediting_1488919 | chrX_120437994_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-10399-5p | chrX | 120437992 | 120437998 | 7mer-m8 | 120437991 | 120438010 | 141 | -11.84 |
| ADediting_1488919 | chrX_120437994_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-6504-3p | chrX | 120437992 | 120437998 | 7mer-m8 | 120437991 | 120438009 | 144 | -11.8 |
| ADediting_1488919 | chrX_120437994_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-7151-3p | chrX | 120437993 | 120438000 | 8mer-1a | 120437993 | 120438013 | 140 | -13.39 |
| ADediting_1488921 | chrX_120438061_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-4435 | chrX | 120438060 | 120438067 | 8mer-1a | 120438060 | 120438081 | 149 | -18.63 |
| ADediting_1488921 | chrX_120438061_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-4781-3p | chrX | 120438057 | 120438063 | 7mer-m8 | 120438056 | 120438074 | 144 | -13.86 |
| ADediting_1488922 | chrX_120438070_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-3663-5p | chrX | 120438069 | 120438075 | 7mer-m8 | 120438068 | 120438087 | 144 | -21.71 |
| ADediting_1488922 | chrX_120438070_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-6131 | chrX | 120438068 | 120438074 | 7mer-m8 | 120438067 | 120438085 | 140 | -16.72 |
| ADediting_1488922 | chrX_120438070_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-6843-3p | chrX | 120438070 | 120438076 | 7mer-m8 | 120438069 | 120438088 | 152 | -20.01 |
| ADediting_1488922 | chrX_120438070_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-6848-3p | chrX | 120438070 | 120438076 | 7mer-m8 | 120438069 | 120438086 | 142 | -15.32 |
| ADediting_1488923 | chrX_120438073_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-3663-5p | chrX | 120438069 | 120438075 | 7mer-m8 | 120438068 | 120438087 | 144 | -21.71 |
| ADediting_1488923 | chrX_120438073_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-6131 | chrX | 120438068 | 120438074 | 7mer-m8 | 120438067 | 120438085 | 140 | -16.72 |
| ADediting_1488923 | chrX_120438073_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-6843-3p | chrX | 120438070 | 120438076 | 7mer-m8 | 120438069 | 120438088 | 152 | -20.01 |
| ADediting_1488923 | chrX_120438073_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-6848-3p | chrX | 120438070 | 120438076 | 7mer-m8 | 120438069 | 120438086 | 142 | -15.32 |
| ADediting_1488924 | chrX_120438075_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-371a-5p | chrX | 120438073 | 120438080 | 8mer-1a | 120438073 | 120438092 | 150 | -18.15 |
| ADediting_1488924 | chrX_120438075_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-6843-3p | chrX | 120438070 | 120438076 | 7mer-m8 | 120438069 | 120438088 | 152 | -20.01 |
| ADediting_1488924 | chrX_120438075_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-6848-3p | chrX | 120438070 | 120438076 | 7mer-m8 | 120438069 | 120438086 | 142 | -15.32 |
| ADediting_1488925 | chrX_120438084_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-3176 | chrX | 120438083 | 120438089 | 7mer-m8 | 120438082 | 120438104 | 147 | -21.78 |
| ADediting_1488925 | chrX_120438084_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-3922-3p | chrX | 120438083 | 120438089 | 7mer-m8 | 120438082 | 120438102 | 153 | -18.19 |
| ADediting_1488925 | chrX_120438084_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-6878-3p | chrX | 120438084 | 120438090 | 7mer-m8 | 120438083 | 120438105 | 142 | -23.66 |
| ADediting_1488926 | chrX_120438094_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-1245a | chrX | 120438092 | 120438098 | 7mer-m8 | 120438091 | 120438111 | 146 | -18.91 |
| ADediting_1488926 | chrX_120438094_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-640 | chrX | 120438094 | 120438100 | 7mer-m8 | 120438093 | 120438115 | 150 | -18.79 |
| ADediting_1488926 | chrX_120438094_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-8079 | chrX | 120438092 | 120438098 | 7mer-m8 | 120438091 | 120438109 | 147 | -14.14 |
| ADediting_1488928 | chrX_120438129_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-10399-5p | chrX | 120438128 | 120438134 | 7mer-m8 | 120438127 | 120438147 | 140 | -10.39 |
| ADediting_1488928 | chrX_120438129_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-5089-5p | chrX | 120438124 | 120438130 | 7mer-m8 | 120438123 | 120438145 | 148 | -14.93 |
| ADediting_1488928 | chrX_120438129_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-6504-3p | chrX | 120438128 | 120438134 | 7mer-m8 | 120438127 | 120438148 | 141 | -11.32 |
| ADediting_1488929 | chrX_120438130_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-10399-5p | chrX | 120438128 | 120438134 | 7mer-m8 | 120438127 | 120438147 | 140 | -10.39 |
| ADediting_1488929 | chrX_120438130_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-6504-3p | chrX | 120438128 | 120438134 | 7mer-m8 | 120438127 | 120438148 | 141 | -11.32 |
| ADediting_1488929 | chrX_120438130_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-7151-3p | chrX | 120438129 | 120438136 | 8mer-1a | 120438129 | 120438149 | 146 | -16.2 |
| ADediting_1674573 | chrX_120437945_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-6778-3p | chrX | 120437941 | 120437948 | 8mer-1a | 120437941 | 120437959 | 143 | -17.49 |
| ADediting_1674573 | chrX_120437945_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-6791-3p | chrX | 120437941 | 120437947 | 7mer-1a | 120437941 | 120437960 | 140 | -23.05 |
| ADediting_1674573 | chrX_120437945_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-6836-3p | chrX | 120437941 | 120437947 | 7mer-m8 | 120437940 | 120437960 | 145 | -19.03 |
| ADediting_1674574 | chrX_120437967_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-1976 | chrX | 120437962 | 120437969 | 8mer-1a | 120437962 | 120437982 | 149 | -24.39 |
| ADediting_1674574 | chrX_120437967_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-6747-3p | chrX | 120437964 | 120437971 | 8mer-1a | 120437964 | 120437986 | 149 | -23.68 |
| ADediting_1674575 | chrX_120438020_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-4735-5p | chrX | 120438019 | 120438025 | 7mer-m8 | 120438018 | 120438039 | 140 | -6.81 |
| ADediting_1674576 | chrX_120438050_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-193b-5p | chrX | 120438045 | 120438052 | 8mer-1a | 120438045 | 120438066 | 142 | -15.74 |
| ADediting_1674576 | chrX_120438050_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-3170 | chrX | 120438045 | 120438051 | 7mer-m8 | 120438044 | 120438065 | 140 | -13.8 |
| ADediting_1674576 | chrX_120438050_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-6855-5p | chrX | 120438045 | 120438051 | 7mer-m8 | 120438044 | 120438068 | 145 | -17.8 |
| ADediting_1674577 | chrX_120438060_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-4716-5p | chrX | 120438055 | 120438061 | 7mer-m8 | 120438054 | 120438075 | 140 | -11.3 |
| ADediting_1674577 | chrX_120438060_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-4781-3p | chrX | 120438057 | 120438063 | 7mer-m8 | 120438056 | 120438074 | 144 | -13.86 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1391023 | chr8_140732605_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-151a-3p | chrX | 120439056 | 120439062 | 7mer-m8 | 120439055 | 120439075 | 153 | -19.15 |
| ADediting_1535953 | chr14_101045971_+ | ENSG00000005893.15 | ENST00000200639.8 | LAMP2-201 | hsa-miR-381-3p | chrX | 120430876 | 120430882 | 7mer-1a | 120430876 | 120430897 | 144 | -18.51 |
| ADediting_1535953 | chr14_101045971_+ | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-381-3p | chrX | 120437765 | 120437771 | 7mer-m8 | 120437764 | 120437786 | 146 | -11.57 |
| ADediting_1535953 | chr14_101045971_+ | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-381-3p | chrX | 120437830 | 120437836 | 7mer-m8 | 120437829 | 120437850 | 140 | -8.54 |
| ADediting_1535953 | chr14_101045971_+ | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-381-3p | chrX | 120438160 | 120438166 | 7mer-m8 | 120438159 | 120438180 | 140 | -8.54 |
| ADediting_291761 | chr11_93733708_- | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-1304-3p | chrX | 120437128 | 120437134 | 7mer-m8 | 120437127 | 120437147 | 168 | -22.79 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-4775 | chrX | 120438919 | 120438925 | 7mer-m8 | 120438918 | 120438939 | 147 | -7.53 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000005893.15 | ENST00000434600.6 | LAMP2-203 | hsa-miR-4775 | chrX | 120428124 | 120428131 | 8mer-1a | 120428124 | 120428146 | 143 | -7.89 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-5585-3p | chrX | 120437386 | 120437392 | 7mer-m8 | 120437385 | 120437407 | 152 | -14.9 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000005893.15 | ENST00000434600.6 | LAMP2-203 | hsa-miR-5688 | chrX | 120428462 | 120428468 | 7mer-m8 | 120428461 | 120428483 | 154 | -12.67 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000005893.15 | ENST00000200639.8 | LAMP2-201 | hsa-miR-589-3p | chrX | 120430929 | 120430935 | 7mer-m8 | 120430928 | 120430951 | 140 | -15.39 |
| ADediting_1535951 | chr14_100874558_+ | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-337-3p | chrX | 120437583 | 120437589 | 7mer-m8 | 120437582 | 120437603 | 140 | -10.99 |
| ADediting_291761 | chr11_93733708_- | ENSG00000005893.15 | ENST00000434600.6 | LAMP2-203 | hsa-miR-1304-3p | chrX | 120428367 | 120428373 | 7mer-m8 | 120428366 | 120428387 | 147 | -14.5 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000005893.15 | ENST00000371335.4 | LAMP2-202 | hsa-miR-4775 | chrX | 120438296 | 120438303 | 8mer-1a | 120438296 | 120438318 | 147 | -8.34 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for LAMP2 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000371335.4 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_1674568 | ENST00000371335.4 | chrX_120437882_- | 2642 | -1052.47 | -1052.07 | -1079.67 |
| ADediting_1488909 | ENST00000371335.4 | chrX_120437883_- | 2641 | -1053.77 | -1052.07 | -1079.67 |
| ADediting_1674569 | ENST00000371335.4 | chrX_120437884_- | 2640 | -1053.77 | -1052.07 | -1079.67 |
| ADediting_1674570 | ENST00000371335.4 | chrX_120437887_- | 2637 | -1052.77 | -1052.07 | -1079.67 |
| ADediting_1674571 | ENST00000371335.4 | chrX_120437889_- | 2635 | -1053.47 | -1052.07 | -1079.67 |
| ADediting_1674572 | ENST00000371335.4 | chrX_120437916_- | 2608 | -1055.87 | -1052.07 | -1079.67 |
| ADediting_1488910 | ENST00000371335.4 | chrX_120437923_- | 2601 | -1054.17 | -1052.07 | -1079.67 |
| ADediting_1488911 | ENST00000371335.4 | chrX_120437924_- | 2600 | -1051.97 | -1052.07 | -1079.67 |
| ADediting_1488912 | ENST00000371335.4 | chrX_120437941_- | 2583 | -1055.57 | -1052.07 | -1079.67 |
| ADediting_1674573 | ENST00000371335.4 | chrX_120437945_- | 2579 | -1052.27 | -1052.07 | -1079.67 |
| ADediting_1488913 | ENST00000371335.4 | chrX_120437952_- | 2572 | -1054.57 | -1052.07 | -1079.67 |
| ADediting_1488914 | ENST00000371335.4 | chrX_120437958_- | 2566 | -1053.07 | -1052.07 | -1079.67 |
| ADediting_1488915 | ENST00000371335.4 | chrX_120437961_- | 2563 | -1052.57 | -1052.07 | -1079.67 |
| ADediting_1674574 | ENST00000371335.4 | chrX_120437967_- | 2557 | -1052.77 | -1052.07 | -1079.67 |
| ADediting_1488916 | ENST00000371335.4 | chrX_120437984_- | 2540 | -1052.07 | -1052.07 | -1079.67 |
| ADediting_1488917 | ENST00000371335.4 | chrX_120437988_- | 2536 | -1054.67 | -1052.07 | -1079.67 |
| ADediting_1488918 | ENST00000371335.4 | chrX_120437993_- | 2531 | -1052.97 | -1052.07 | -1079.67 |
| ADediting_1488919 | ENST00000371335.4 | chrX_120437994_- | 2530 | -1052.07 | -1052.07 | -1079.67 |
| ADediting_1674575 | ENST00000371335.4 | chrX_120438020_- | 2504 | -1052.97 | -1052.07 | -1079.67 |
| ADediting_1488920 | ENST00000371335.4 | chrX_120438027_- | 2497 | -1052.27 | -1052.07 | -1079.67 |
| ADediting_1674576 | ENST00000371335.4 | chrX_120438050_- | 2474 | -1052.07 | -1052.07 | -1079.67 |
| ADediting_1674577 | ENST00000371335.4 | chrX_120438060_- | 2464 | -1052.37 | -1052.07 | -1079.67 |
| ADediting_1488921 | ENST00000371335.4 | chrX_120438061_- | 2463 | -1054.37 | -1052.07 | -1079.67 |
| ADediting_1488922 | ENST00000371335.4 | chrX_120438070_- | 2454 | -1052.07 | -1052.07 | -1079.67 |
| ADediting_1488923 | ENST00000371335.4 | chrX_120438073_- | 2451 | -1051.67 | -1052.07 | -1079.67 |
| ADediting_1488924 | ENST00000371335.4 | chrX_120438075_- | 2449 | -1052.57 | -1052.07 | -1079.67 |
| ADediting_1488925 | ENST00000371335.4 | chrX_120438084_- | 2440 | -1051.37 | -1052.07 | -1079.67 |
| ADediting_1488926 | ENST00000371335.4 | chrX_120438094_- | 2430 | -1051.67 | -1052.07 | -1079.67 |
| ADediting_1488927 | ENST00000371335.4 | chrX_120438106_- | 2418 | -1055.27 | -1052.07 | -1079.67 |
| ADediting_1488928 | ENST00000371335.4 | chrX_120438129_- | 2395 | -1053.67 | -1052.07 | -1079.67 |
| ADediting_1488929 | ENST00000371335.4 | chrX_120438130_- | 2394 | -1057.77 | -1052.07 | -1079.67 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for LAMP2 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_1488891 | chrX_120434974_- | 0.345467832967009 | 0.0537608863368093 | 0.0866154590416538 | -0.0974837366441949 | 1.35309494460604e-09 | 0.335562863308224 |
| STG | ADediting_1488891 | chrX_120434974_- | 0.30858987283338 | 0.11242501703238 | 0.805045056601245 | -0.0273351743590636 | 0.000790605484970914 | 0.35925372655778 |
| CER | ADediting_1488894 | chrX_120435008_- | 7.71956345337834e-05 | 0.31704199645104 | 0.00448915882949362 | 0.230803196613781 | 0.179297356289853 | 0.11023678129673 |
| TCX | ADediting_1488894 | chrX_120435008_- | 0.00784096287872125 | 0.21632639882419 | 0.453010403170916 | -0.0617282923793985 | 3.57364740453675e-07 | 0.401372862787092 |
| TCX | ADediting_1488895 | chrX_120435018_- | 0.000928824569691602 | 0.267650897383125 | 0.862074837162109 | 0.0143042242124925 | 2.21979959317447e-05 | 0.338853716725254 |
| DLPFC | ADediting_1488898 | chrX_120435043_- | 0.448167571082841 | 0.0432329049933201 | 0.10114011931212 | -0.093282614656555 | 6.36184696508521e-14 | 0.408880902442106 |
| DLPFC | ADediting_1488899 | chrX_120435044_- | 0.970363559212195 | -0.00211866625416111 | 0.0367405959103198 | -0.118686359157166 | 1.54190609181114e-08 | 0.314374307241693 |
| CER | ADediting_1488899 | chrX_120435044_- | 8.78663354423621e-05 | 0.314677627394776 | 0.0038179893729731 | 0.234849770670598 | 0.279907664862161 | 0.0887930455933837 |
| CER | ADediting_1488902 | chrX_120435054_- | 9.83963761225073e-06 | 0.352254830017804 | 0.000511521535584811 | 0.280338400828328 | 0.0085664426191993 | 0.213946324600899 |
| TCX | ADediting_1488902 | chrX_120435054_- | 0.000391833916454345 | 0.28581871091449 | 0.745051796616162 | 0.0267692639422545 | 1.14316647569724e-05 | 0.349830185272889 |
| STG | ADediting_1488902 | chrX_120435054_- | 0.484970175496803 | 0.0772375485085417 | 0.294895741626584 | -0.11563404220007 | 0.00317542271195215 | 0.31825064439439 |
| TCX | ADediting_1488905 | chrX_120435073_- | 0.0013814201839442 | 0.258856290451394 | 0.95593180094365 | 0.00454995096599722 | 7.7873099290303e-05 | 0.31688305469617 |
| CER | ADediting_1488906 | chrX_120435078_- | 4.20645201519797e-06 | 0.365630990135047 | 0.000228284556462359 | 0.296598153391358 | 0.482034564871245 | 0.0578382504047355 |
| TCX | ADediting_1488906 | chrX_120435078_- | 1.44762935165945e-05 | 0.345971581011166 | 0.385804916161306 | 0.0713170653376081 | 0.000154402524135263 | 0.304144878696025 |
| CER | ADediting_1488912 | chrX_120437941_- | 0.000725310210621683 | 0.272984893242426 | 1.44583258454923e-06 | 0.381633129927311 | 0.0628173460994505 | 0.152294392081035 |
| DLPFC | ADediting_1488931 | chrX_120451533_- | 0.0351313854590409 | 0.119713482225153 | 0.669313774006884 | -0.0243518600935552 | 1.98235782217867e-21 | 0.50459169383645 |
| DLPFC | ADediting_1488948 | chrX_120453565_- | 0.0171301198344292 | 0.135319908840125 | 0.672874025000286 | 0.024073514499758 | 1.87757729503184e-09 | 0.33280322629944 |
| DLPFC | ADediting_1488952 | chrX_120453708_- | 0.648343149622407 | 0.0260034252294016 | 0.133298625318087 | -0.0854527573947457 | 4.86799153477561e-14 | 0.410618574272629 |
| DLPFC | ADediting_1488953 | chrX_120453722_- | 0.132924784106847 | 0.0855348458384217 | 0.603238551481088 | 0.0296329841357209 | 1.2872210395295e-09 | 0.3359809131802 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 1.2045122719356e-18 | 0.472501580724036 | 4.15167204611658e-07 | 0.282749321062951 | 3.37139425215738e-05 | 0.233209557362533 |
| AC | 1.05422379522737e-47 | 0.75683201720496 | 3.13269880922763e-27 | 0.613383715751529 | 7.43775177827667e-31 | 0.645449020411544 |
| PCC | 3.53803597101022e-11 | 0.455584109406263 | 3.26520243897287e-09 | 0.411745167005889 | 4.25138251711912e-08 | 0.383756096685909 |
| CER | 1.8260479679999e-23 | 0.700749687484952 | 5.99398234360336e-11 | 0.501954327569839 | 2.8245880748979e-11 | 0.509300365868377 |
| TCX | 1.62440600562662e-05 | 0.344070218927767 | 0.0165778092577875 | -0.195372973853808 | 4.3106265957975e-30 | 0.765117304352474 |
| FP | 8.72829675572284e-10 | 0.439083968623686 | 1.8627232284345e-13 | 0.515214668520293 | 7.02373468665834e-11 | 0.463807147266141 |
| IFG | 0.541355362218729 | 0.128211026999616 | 0.480261893451906 | -0.147971737176279 | 0.0469728451272128 | 0.400985722190484 |
| PG | 1.36499957854449e-36 | 0.762190675677693 | 1.96174405854188e-12 | 0.486323782171308 | 0.0029881546117144 | 0.216564717000395 |
| STG | 1.00027133524e-07 | 0.542173519278909 | 0.00123169534921496 | 0.346766576528422 | 3.26295832920686e-05 | 0.436825407376503 |
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Relation with AD stages for LAMP2 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| TCX | ADediting_1488885 | chrX_120434866_- | 0.000348978438031071 | 0.340903021263325 |
| TCX | ADediting_1488891 | chrX_120434974_- | 0.000409416571498854 | 0.337137671356326 |
| TCX | ADediting_1488894 | chrX_120435008_- | 1.45934813909779e-06 | 0.44810326608643 |
| TCX | ADediting_1488895 | chrX_120435018_- | 0.000658476190970682 | 0.325644826813527 |
| TCX | ADediting_1488898 | chrX_120435043_- | 0.00158772670631833 | 0.303091391214882 |
| TCX | ADediting_1488899 | chrX_120435044_- | 0.00123511970231349 | 0.30970724454296 |
| TCX | ADediting_1488902 | chrX_120435054_- | 9.23947766645455e-06 | 0.415941582549486 |
| TCX | ADediting_1488903 | chrX_120435067_- | 2.62023414239807e-05 | 0.396203145577887 |
| TCX | ADediting_1488905 | chrX_120435073_- | 3.19448622638755e-05 | 0.39230499717469 |
| TCX | ADediting_1488906 | chrX_120435078_- | 2.19097811502106e-05 | 0.399681171119496 |
| TCX | ADediting_1488908 | chrX_120435130_- | 0.000281292747752217 | 0.345911974354968 |
| TCX | ADediting_1488919 | chrX_120437994_- | 0.000354262242042311 | 0.340550779237837 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 1.34977004685888e-05 | 0.405354504867835 |
| TCX | 6.25915433882356e-09 | 0.527485316288046 |
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RelatedDrugs for LAMP2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for LAMP2 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| LAMP2 | C0878677 | Glycogen Storage Disease Type IIb | 9 | CLINGEN;CTD_human;ORPHANET;UNIPROT |
| LAMP2 | C0270960 | Congenital myopathy (disorder) | 2 | GENOMICS_ENGLAND |
| LAMP2 | C0003886 | Arthrogryposis | 1 | GENOMICS_ENGLAND |
| LAMP2 | C0038220 | Status Epilepticus | 1 | CTD_human |
| LAMP2 | C0270823 | Petit mal status | 1 | CTD_human |
| LAMP2 | C0311335 | Grand Mal Status Epilepticus | 1 | CTD_human |
| LAMP2 | C0393734 | Complex Partial Status Epilepticus | 1 | CTD_human |
| LAMP2 | C0751522 | Status Epilepticus, Subclinical | 1 | CTD_human |
| LAMP2 | C0751523 | Non-Convulsive Status Epilepticus | 1 | CTD_human |
| LAMP2 | C0751524 | Simple Partial Status Epilepticus | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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