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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for ARHGAP1

check button Gene summary
Gene informationGene symbol

ARHGAP1

Gene ID

392

Gene nameRho GTPase activating protein 1
SynonymsCDC42GAP|RHOGAP|RHOGAP1|p50rhoGAP
Cytomap

11p11.2

Type of geneprotein-coding
Descriptionrho GTPase-activating protein 1CDC42 GTPase-activating proteinGTPase-activating protein rhoGAPGTPase-activating protein rhoOGAPGTPase-activating protein, Rho, 1rho-related small GTPase protein activatorrho-type GTPase-activating protein 1
Modification date20200313
UniProtAcc

Q07960,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
ARHGAP1

GO:0007264

small GTPase mediated signal transduction

8253717|8288572


Top

RNA A-to-I events for ARHGAP1

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_254267(46681689, -), ADediting_254268(46681713, -), ADediting_254269(46682427, -), ADediting_254270(46682439, -), ADediting_254271(46682440, -), ADediting_254272(46682441, -), ADediting_254273(46682518, -), ADediting_254274(46682535, -), ADediting_254275(46682536, -), ADediting_254276(46682552, -), ADediting_254277(46682560, -), ADediting_254278(46682562, -), ADediting_254279(46682572, -), ADediting_254280(46682597, -), ADediting_254281(46682601, -), ADediting_254282(46682602, -), ADediting_254283(46682637, -), ADediting_254284(46682648, -), ADediting_254285(46682651, -), ADediting_254286(46682671, -), ADediting_254287(46682679, -), ADediting_254288(46682681, -), ADediting_254289(46683123, -), ADediting_254290(46683136, -), ADediting_254291(46683137, -), ADediting_254292(46683142, -), ADediting_254293(46683150, -), ADediting_254294(46683163, -), ADediting_254295(46683167, -), ADediting_254296(46683170, -), ADediting_254297(46683183, -), ADediting_254298(46683242, -), ADediting_254299(46683261, -), ADediting_254300(46683270, -), ADediting_254301(46683286, -), ADediting_254302(46683340, -), ADediting_254303(46683706, -), ADediting_254304(46683726, -), ADediting_254305(46683743, -), ADediting_254306(46683746, -), ADediting_254307(46683769, -), ADediting_254308(46683778, -), ADediting_254309(46683781, -), ADediting_254310(46683789, -), ADediting_254311(46683805, -), ADediting_254312(46683813, -), ADediting_254313(46683886, -), ADediting_254314(46684831, -), ADediting_254315(46684843, -), ADediting_254316(46684844, -), ADediting_254317(46684896, -), ADediting_254318(46684916, -), ADediting_254319(46684920, -), ADediting_254320(46684922, -), ADediting_254321(46684925, -), ADediting_254322(46684939, -), ADediting_254323(46684940, -), ADediting_254324(46684944, -), ADediting_254325(46684948, -), ADediting_254326(46684964, -), ADediting_254327(46684966, -), ADediting_254328(46684976, -), ADediting_254329(46684988, -), ADediting_254330(46685001, -), ADediting_254331(46685005, -), ADediting_254332(46685006, -), ADediting_254333(46685011, -), ADediting_254334(46685019, -), ADediting_254335(46685031, -), ADediting_254336(46685044, -), ADediting_254337(46685355, -), ADediting_254338(46685390, -), ADediting_254339(46685393, -), ADediting_254340(46685395, -), ADediting_254341(46685420, -), ADediting_254342(46685424, -), ADediting_254343(46685430, -), ADediting_254344(46685452, -), ADediting_254345(46685456, -), ADediting_254346(46685466, -), ADediting_254347(46685482, -), ADediting_254348(46685488, -), ADediting_254349(46685492, -), ADediting_254350(46685509, -), ADediting_254351(46685520, -), ADediting_254352(46685521, -), ADediting_254353(46685522, -), ADediting_254354(46685554, -), ADediting_254355(46685559, -), ADediting_254356(46685598, -), ADediting_254357(46685764, -), ADediting_254358(46685789, -), ADediting_254359(46685803, -), ADediting_254360(46685817, -), ADediting_254361(46685854, -), ADediting_254362(46685879, -), ADediting_254363(46685946, -), ADediting_254364(46685947, -), ADediting_254365(46686034, -), ADediting_254366(46686057, -), ADediting_254367(46686068, -), ADediting_254368(46686074, -), ADediting_254369(46686080, -), ADediting_254370(46686081, -), ADediting_254371(46686083, -), ADediting_254372(46686095, -), ADediting_254373(46686096, -), ADediting_254374(46686114, -), ADediting_254375(46686131, -), ADediting_254376(46686151, -), ADediting_254377(46686155, -), ADediting_254378(46686158, -), ADediting_254379(46686163, -), ADediting_254380(46686164, -), ADediting_254381(46686167, -), ADediting_254382(46686169, -), ADediting_254383(46686170, -), ADediting_254384(46686193, -), ADediting_254385(46686210, -), ADediting_254386(46686213, -), ADediting_254387(46686218, -), ADediting_254388(46686221, -), ADediting_254389(46686504, -), ADediting_254390(46686691, -), ADediting_254391(46687438, -), ADediting_254392(46688514, -), ADediting_254393(46688536, -), ADediting_254394(46688560, -), ADediting_254395(46688574, -), ADediting_254396(46688579, -), ADediting_254397(46688596, -), ADediting_254398(46688620, -), ADediting_254399(46688638, -), ADediting_254400(46688681, -), ADediting_254401(46688685, -), ADediting_254402(46688702, -), ADediting_254403(46688742, -), ADediting_254404(46688747, -), ADediting_254405(46688748, -), ADediting_254406(46688817, -), ADediting_254407(46688826, -), ADediting_254408(46688835, -), ADediting_254409(46688838, -), ADediting_254410(46688839, -), ADediting_254411(46688878, -), ADediting_254412(46688892, -), ADediting_254413(46688901, -), ADediting_254414(46688960, -), ADediting_254415(46688972, -), ADediting_254416(46688984, -), ADediting_254417(46689001, -), ADediting_254418(46689008, -), ADediting_254419(46689021, -), ADediting_254420(46689032, -), ADediting_254421(46689040, -), ADediting_254422(46689046, -), ADediting_254423(46689637, -), ADediting_254424(46689689, -), ADediting_254425(46689744, -), ADediting_254426(46689745, -), ADediting_254427(46689768, -), ADediting_254428(46689785, -), ADediting_254429(46689790, -), ADediting_254430(46689811, -), ADediting_254431(46689812, -), ADediting_254432(46690120, -), ADediting_254433(46690147, -), ADediting_254434(46690187, -), ADediting_254435(46690208, -), ADediting_254436(46690209, -), ADediting_254437(46690265, -), ADediting_254438(46690275, -), ADediting_254439(46690287, -), ADediting_254440(46690324, -), ADediting_254441(46690368, -), ADediting_254442(46690487, -), ADediting_254443(46690505, -), ADediting_254444(46691347, -), ADediting_254445(46691423, -), ADediting_254446(46691576, -), ADediting_254447(46691645, -), ADediting_254448(46691694, -), ADediting_254449(46691791, -), ADediting_254450(46691860, -), ADediting_254451(46691863, -), ADediting_254452(46692750, -), ADediting_254453(46692780, -), ADediting_254454(46692825, -), ADediting_254455(46693124, -), ADediting_254456(46693544, -), ADediting_254457(46693557, -), ADediting_254458(46693629, -), ADediting_1526935(46681607, -), ADediting_1526936(46681661, -), ADediting_1526937(46683310, -), ADediting_1526938(46683334, -), ADediting_1526939(46683833, -), ADediting_1526940(46683834, -), ADediting_1526941(46683853, -), ADediting_1526942(46684950, -), ADediting_1526943(46685425, -), ADediting_1526944(46685433, -), ADediting_1526945(46685551, -), ADediting_1526946(46686077, -), ADediting_1526947(46686161, -), ADediting_1526948(46686234, -), ADediting_1610004(46688756, -),

Top

RNA editing positional annotations for ARHGAP1 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_254267chr11_46681689_-intronic
ADediting_254268chr11_46681713_-intronic
ADediting_254269chr11_46682427_-intronic
ADediting_254270chr11_46682439_-intronic
ADediting_254271chr11_46682440_-intronic
ADediting_254272chr11_46682441_-intronic
ADediting_254273chr11_46682518_-intronic
ADediting_254274chr11_46682535_-intronic
ADediting_254275chr11_46682536_-intronic
ADediting_254276chr11_46682552_-intronic
ADediting_254277chr11_46682560_-intronic
ADediting_254278chr11_46682562_-intronic
ADediting_254279chr11_46682572_-intronic
ADediting_254280chr11_46682597_-intronic
ADediting_254281chr11_46682601_-intronic
ADediting_254282chr11_46682602_-intronic
ADediting_254283chr11_46682637_-intronic
ADediting_254284chr11_46682648_-intronic
ADediting_254285chr11_46682651_-intronic
ADediting_254286chr11_46682671_-intronic
ADediting_254287chr11_46682679_-intronic
ADediting_254288chr11_46682681_-intronic
ADediting_254289chr11_46683123_-intronic
ADediting_254290chr11_46683136_-intronic
ADediting_254291chr11_46683137_-intronic
ADediting_254292chr11_46683142_-intronic
ADediting_254293chr11_46683150_-intronic
ADediting_254294chr11_46683163_-intronic
ADediting_254295chr11_46683167_-intronic
ADediting_254296chr11_46683170_-intronic
ADediting_254297chr11_46683183_-intronic
ADediting_254298chr11_46683242_-intronic
ADediting_254299chr11_46683261_-intronic
ADediting_254300chr11_46683270_-intronic
ADediting_254301chr11_46683286_-intronic
ADediting_254302chr11_46683340_-intronic
ADediting_254303chr11_46683706_-intronic
ADediting_254304chr11_46683726_-intronic
ADediting_254305chr11_46683743_-intronic
ADediting_254306chr11_46683746_-intronic
ADediting_254307chr11_46683769_-intronic
ADediting_254308chr11_46683778_-intronic
ADediting_254309chr11_46683781_-intronic
ADediting_254310chr11_46683789_-intronic
ADediting_254311chr11_46683805_-intronic
ADediting_254312chr11_46683813_-intronic
ADediting_254313chr11_46683886_-intronic
ADediting_254314chr11_46684831_-intronic
ADediting_254315chr11_46684843_-intronic
ADediting_254316chr11_46684844_-intronic
ADediting_254317chr11_46684896_-intronic
ADediting_254318chr11_46684916_-intronic
ADediting_254319chr11_46684920_-intronic
ADediting_254320chr11_46684922_-intronic
ADediting_254321chr11_46684925_-intronic
ADediting_254322chr11_46684939_-intronic
ADediting_254323chr11_46684940_-intronic
ADediting_254324chr11_46684944_-intronic
ADediting_254325chr11_46684948_-intronic
ADediting_254326chr11_46684964_-intronic
ADediting_254327chr11_46684966_-intronic
ADediting_254328chr11_46684976_-intronic
ADediting_254329chr11_46684988_-intronic
ADediting_254330chr11_46685001_-intronic
ADediting_254331chr11_46685005_-intronic
ADediting_254332chr11_46685006_-intronic
ADediting_254333chr11_46685011_-intronic
ADediting_254334chr11_46685019_-intronic
ADediting_254335chr11_46685031_-intronic
ADediting_254336chr11_46685044_-intronic
ADediting_254337chr11_46685355_-intronic
ADediting_254338chr11_46685390_-intronic
ADediting_254339chr11_46685393_-intronic
ADediting_254340chr11_46685395_-intronic
ADediting_254341chr11_46685420_-intronic
ADediting_254342chr11_46685424_-intronic
ADediting_254343chr11_46685430_-intronic
ADediting_254344chr11_46685452_-intronic
ADediting_254345chr11_46685456_-intronic
ADediting_254346chr11_46685466_-intronic
ADediting_254347chr11_46685482_-intronic
ADediting_254348chr11_46685488_-intronic
ADediting_254349chr11_46685492_-intronic
ADediting_254350chr11_46685509_-intronic
ADediting_254351chr11_46685520_-intronic
ADediting_254352chr11_46685521_-intronic
ADediting_254353chr11_46685522_-intronic
ADediting_254354chr11_46685554_-intronic
ADediting_254355chr11_46685559_-intronic
ADediting_254356chr11_46685598_-intronic
ADediting_254357chr11_46685764_-intronic
ADediting_254358chr11_46685789_-intronic
ADediting_254359chr11_46685803_-intronic
ADediting_254360chr11_46685817_-intronic
ADediting_254361chr11_46685854_-intronic
ADediting_254362chr11_46685879_-intronic
ADediting_254363chr11_46685946_-intronic
ADediting_254364chr11_46685947_-intronic
ADediting_254365chr11_46686034_-intronic
ADediting_254366chr11_46686057_-intronic
ADediting_254367chr11_46686068_-intronic
ADediting_254368chr11_46686074_-intronic
ADediting_254369chr11_46686080_-intronic
ADediting_254370chr11_46686081_-intronic
ADediting_254371chr11_46686083_-intronic
ADediting_254372chr11_46686095_-intronic
ADediting_254373chr11_46686096_-intronic
ADediting_254374chr11_46686114_-intronic
ADediting_254375chr11_46686131_-intronic
ADediting_254376chr11_46686151_-intronic
ADediting_254377chr11_46686155_-intronic
ADediting_254378chr11_46686158_-intronic
ADediting_254379chr11_46686163_-intronic
ADediting_254380chr11_46686164_-intronic
ADediting_254381chr11_46686167_-intronic
ADediting_254382chr11_46686169_-intronic
ADediting_254383chr11_46686170_-intronic
ADediting_254384chr11_46686193_-intronic
ADediting_254385chr11_46686210_-intronic
ADediting_254386chr11_46686213_-intronic
ADediting_254387chr11_46686218_-intronic
ADediting_254388chr11_46686221_-intronic
ADediting_254389chr11_46686504_-intronic
ADediting_254390chr11_46686691_-intronic
ADediting_254391chr11_46687438_-intronic
ADediting_254392chr11_46688514_-intronic
ADediting_254393chr11_46688536_-intronic
ADediting_254394chr11_46688560_-intronic
ADediting_254395chr11_46688574_-intronic
ADediting_254396chr11_46688579_-intronic
ADediting_254397chr11_46688596_-intronic
ADediting_254398chr11_46688620_-intronic
ADediting_254399chr11_46688638_-intronic
ADediting_254400chr11_46688681_-intronic
ADediting_254401chr11_46688685_-intronic
ADediting_254402chr11_46688702_-intronic
ADediting_254403chr11_46688742_-intronic
ADediting_254404chr11_46688747_-intronic
ADediting_254405chr11_46688748_-intronic
ADediting_254406chr11_46688817_-intronic
ADediting_254407chr11_46688826_-intronic
ADediting_254408chr11_46688835_-intronic
ADediting_254409chr11_46688838_-intronic
ADediting_254410chr11_46688839_-intronic
ADediting_254411chr11_46688878_-intronic
ADediting_254412chr11_46688892_-intronic
ADediting_254413chr11_46688901_-intronic
ADediting_254414chr11_46688960_-intronic
ADediting_254415chr11_46688972_-intronic
ADediting_254416chr11_46688984_-intronic
ADediting_254417chr11_46689001_-intronic
ADediting_254418chr11_46689008_-intronic
ADediting_254419chr11_46689021_-intronic
ADediting_254420chr11_46689032_-intronic
ADediting_254421chr11_46689040_-intronic
ADediting_254422chr11_46689046_-intronic
ADediting_254423chr11_46689637_-intronic
ADediting_254424chr11_46689689_-intronic
ADediting_254425chr11_46689744_-intronic
ADediting_254426chr11_46689745_-intronic
ADediting_254427chr11_46689768_-intronic
ADediting_254428chr11_46689785_-intronic
ADediting_254429chr11_46689790_-intronic
ADediting_254430chr11_46689811_-intronic
ADediting_254431chr11_46689812_-intronic
ADediting_254432chr11_46690120_-intronic
ADediting_254433chr11_46690147_-intronic
ADediting_254434chr11_46690187_-intronic
ADediting_254435chr11_46690208_-intronic
ADediting_254436chr11_46690209_-intronic
ADediting_254437chr11_46690265_-intronic
ADediting_254438chr11_46690275_-intronic
ADediting_254439chr11_46690287_-intronic
ADediting_254440chr11_46690324_-intronic
ADediting_254441chr11_46690368_-intronic
ADediting_254442chr11_46690487_-intronic
ADediting_254443chr11_46690505_-intronic
ADediting_254444chr11_46691347_-intronic
ADediting_254445chr11_46691423_-intronic
ADediting_254446chr11_46691576_-intronic
ADediting_254447chr11_46691645_-intronic
ADediting_254448chr11_46691694_-intronic
ADediting_254449chr11_46691791_-intronic
ADediting_254450chr11_46691860_-intronic
ADediting_254451chr11_46691863_-intronic
ADediting_254452chr11_46692750_-intronic
ADediting_254453chr11_46692780_-intronic
ADediting_254454chr11_46692825_-intronic
ADediting_254455chr11_46693124_-intronic
ADediting_254456chr11_46693544_-intronic
ADediting_254457chr11_46693557_-intronic
ADediting_254458chr11_46693629_-intronic
ADediting_1526935chr11_46681607_-intronic
ADediting_1526936chr11_46681661_-intronic
ADediting_1526937chr11_46683310_-intronic
ADediting_1526938chr11_46683334_-intronic
ADediting_1526939chr11_46683833_-intronic
ADediting_1526940chr11_46683834_-intronic
ADediting_1526941chr11_46683853_-intronic
ADediting_1526942chr11_46684950_-intronic
ADediting_1526943chr11_46685425_-intronic
ADediting_1526944chr11_46685433_-intronic
ADediting_1526945chr11_46685551_-intronic
ADediting_1526946chr11_46686077_-intronic
ADediting_1526947chr11_46686161_-intronic
ADediting_1526948chr11_46686234_-intronic
ADediting_1610004chr11_46688756_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_254267chr11_46681689_-SINEAluName=AluSx1
ADediting_254268chr11_46681713_-SINEAluName=AluSx1
ADediting_254269chr11_46682427_-SINEAluName=AluSq
ADediting_254270chr11_46682439_-SINEAluName=AluSq
ADediting_254271chr11_46682440_-SINEAluName=AluSq
ADediting_254272chr11_46682441_-SINEAluName=AluSq
ADediting_254273chr11_46682518_-SINEAluName=AluSq
ADediting_254274chr11_46682535_-SINEAluName=AluSq
ADediting_254275chr11_46682536_-SINEAluName=AluSq
ADediting_254276chr11_46682552_-SINEAluName=AluSq
ADediting_254277chr11_46682560_-SINEAluName=AluSq
ADediting_254278chr11_46682562_-SINEAluName=AluSq
ADediting_254279chr11_46682572_-SINEAluName=AluSq
ADediting_254280chr11_46682597_-SINEAluName=AluSq
ADediting_254281chr11_46682601_-SINEAluName=AluSq
ADediting_254282chr11_46682602_-SINEAluName=AluSq
ADediting_254283chr11_46682637_-SINEAluName=AluSq
ADediting_254284chr11_46682648_-SINEAluName=AluSq
ADediting_254285chr11_46682651_-SINEAluName=AluSq
ADediting_254286chr11_46682671_-SINEAluName=AluSq
ADediting_254287chr11_46682679_-SINEAluName=AluSq
ADediting_254288chr11_46682681_-SINEAluName=AluSq
ADediting_254289chr11_46683123_-SINEAluName=AluJb
ADediting_254290chr11_46683136_-SINEAluName=AluJb
ADediting_254291chr11_46683137_-SINEAluName=AluJb
ADediting_254292chr11_46683142_-SINEAluName=AluJb
ADediting_254293chr11_46683150_-SINEAluName=AluJb
ADediting_254294chr11_46683163_-SINEAluName=AluJb
ADediting_254295chr11_46683167_-SINEAluName=AluJb
ADediting_254296chr11_46683170_-SINEAluName=AluJb
ADediting_254297chr11_46683183_-SINEAluName=AluJb
ADediting_254298chr11_46683242_-SINEAluName=AluJb
ADediting_254299chr11_46683261_-SINEAluName=AluJb
ADediting_254300chr11_46683270_-SINEAluName=AluJb
ADediting_254301chr11_46683286_-SINEAluName=AluJb
ADediting_254302chr11_46683340_-SINEAluName=AluJb
ADediting_254303chr11_46683706_-SINEAluName=AluSp
ADediting_254304chr11_46683726_-SINEAluName=AluSp
ADediting_254305chr11_46683743_-SINEAluName=AluSp
ADediting_254306chr11_46683746_-SINEAluName=AluSp
ADediting_254307chr11_46683769_-SINEAluName=AluSp
ADediting_254308chr11_46683778_-SINEAluName=AluSp
ADediting_254309chr11_46683781_-SINEAluName=AluSp
ADediting_254310chr11_46683789_-SINEAluName=AluSp
ADediting_254311chr11_46683805_-SINEAluName=AluSp
ADediting_254312chr11_46683813_-SINEAluName=AluSp
ADediting_254313chr11_46683886_-SINEAluName=AluSp
ADediting_254314chr11_46684831_-SINEAluName=AluSx
ADediting_254315chr11_46684843_-SINEAluName=AluSx
ADediting_254316chr11_46684844_-SINEAluName=AluSx
ADediting_254317chr11_46684896_-SINEAluName=AluSx
ADediting_254318chr11_46684916_-SINEAluName=AluSx
ADediting_254319chr11_46684920_-SINEAluName=AluSx
ADediting_254320chr11_46684922_-SINEAluName=AluSx
ADediting_254321chr11_46684925_-SINEAluName=AluSx
ADediting_254322chr11_46684939_-SINEAluName=AluSx
ADediting_254323chr11_46684940_-SINEAluName=AluSx
ADediting_254324chr11_46684944_-SINEAluName=AluSx
ADediting_254325chr11_46684948_-SINEAluName=AluSx
ADediting_254326chr11_46684964_-SINEAluName=AluSx
ADediting_254327chr11_46684966_-SINEAluName=AluSx
ADediting_254328chr11_46684976_-SINEAluName=AluSx
ADediting_254329chr11_46684988_-SINEAluName=AluSx
ADediting_254330chr11_46685001_-SINEAluName=AluSx
ADediting_254331chr11_46685005_-SINEAluName=AluSx
ADediting_254332chr11_46685006_-SINEAluName=AluSx
ADediting_254333chr11_46685011_-SINEAluName=AluSx
ADediting_254334chr11_46685019_-SINEAluName=AluSx
ADediting_254335chr11_46685031_-SINEAluName=AluSx
ADediting_254336chr11_46685044_-SINEAluName=AluSx
ADediting_254337chr11_46685355_-SINEAluName=AluSp
ADediting_254338chr11_46685390_-SINEAluName=AluSp
ADediting_254339chr11_46685393_-SINEAluName=AluSp
ADediting_254340chr11_46685395_-SINEAluName=AluSp
ADediting_254341chr11_46685420_-SINEAluName=AluSp
ADediting_254342chr11_46685424_-SINEAluName=AluSp
ADediting_254343chr11_46685430_-SINEAluName=AluSp
ADediting_254344chr11_46685452_-SINEAluName=AluSp
ADediting_254345chr11_46685456_-SINEAluName=AluSp
ADediting_254346chr11_46685466_-SINEAluName=AluSp
ADediting_254347chr11_46685482_-SINEAluName=AluSp
ADediting_254348chr11_46685488_-SINEAluName=AluSp
ADediting_254349chr11_46685492_-SINEAluName=AluSp
ADediting_254350chr11_46685509_-SINEAluName=AluSp
ADediting_254351chr11_46685520_-SINEAluName=AluSp
ADediting_254352chr11_46685521_-SINEAluName=AluSp
ADediting_254353chr11_46685522_-SINEAluName=AluSp
ADediting_254354chr11_46685554_-SINEAluName=AluSp
ADediting_254355chr11_46685559_-SINEAluName=AluSp
ADediting_254356chr11_46685598_-SINEAluName=AluSp
ADediting_254357chr11_46685764_-SINEAluName=AluSc8
ADediting_254358chr11_46685789_-SINEAluName=AluSc8
ADediting_254359chr11_46685803_-SINEAluName=AluSc8
ADediting_254360chr11_46685817_-SINEAluName=AluSc8
ADediting_254361chr11_46685854_-SINEAluName=AluSc8
ADediting_254362chr11_46685879_-SINEAluName=AluSc8
ADediting_254363chr11_46685946_-SINEAluName=AluSc8
ADediting_254364chr11_46685947_-SINEAluName=AluSc8
ADediting_254365chr11_46686034_-SINEAluName=AluSg
ADediting_254366chr11_46686057_-SINEAluName=AluSg
ADediting_254367chr11_46686068_-SINEAluName=AluSg
ADediting_254368chr11_46686074_-SINEAluName=AluSg
ADediting_254369chr11_46686080_-SINEAluName=AluSg
ADediting_254370chr11_46686081_-SINEAluName=AluSg
ADediting_254371chr11_46686083_-SINEAluName=AluSg
ADediting_254372chr11_46686095_-SINEAluName=AluSg
ADediting_254373chr11_46686096_-SINEAluName=AluSg
ADediting_254374chr11_46686114_-SINEAluName=AluSg
ADediting_254375chr11_46686131_-SINEAluName=AluSg
ADediting_254376chr11_46686151_-SINEAluName=AluSg
ADediting_254377chr11_46686155_-SINEAluName=AluSg
ADediting_254378chr11_46686158_-SINEAluName=AluSg
ADediting_254379chr11_46686163_-SINEAluName=AluSg
ADediting_254380chr11_46686164_-SINEAluName=AluSg
ADediting_254381chr11_46686167_-SINEAluName=AluSg
ADediting_254382chr11_46686169_-SINEAluName=AluSg
ADediting_254383chr11_46686170_-SINEAluName=AluSg
ADediting_254384chr11_46686193_-SINEAluName=AluSg
ADediting_254385chr11_46686210_-SINEAluName=AluSg
ADediting_254386chr11_46686213_-SINEAluName=AluSg
ADediting_254387chr11_46686218_-SINEAluName=AluSg
ADediting_254388chr11_46686221_-SINEAluName=AluSg
ADediting_254389chr11_46686504_-SINEAluName=AluY
ADediting_254390chr11_46686691_-SINEAluName=AluY
ADediting_254392chr11_46688514_-SINEAluName=AluJr4
ADediting_254393chr11_46688536_-SINEAluName=AluJr4
ADediting_254394chr11_46688560_-SINEAluName=AluJr4
ADediting_254395chr11_46688574_-SINEAluName=AluJr4
ADediting_254396chr11_46688579_-SINEAluName=AluJr4
ADediting_254397chr11_46688596_-SINEAluName=AluJr4
ADediting_254398chr11_46688620_-SINEAluName=AluJr4
ADediting_254399chr11_46688638_-SINEAluName=AluJr4
ADediting_254400chr11_46688681_-SINEAluName=AluJr4
ADediting_254401chr11_46688685_-SINEAluName=AluJr4
ADediting_254402chr11_46688702_-SINEAluName=AluJr4
ADediting_254403chr11_46688742_-SINEAluName=AluJr4
ADediting_254404chr11_46688747_-SINEAluName=AluJr4
ADediting_254405chr11_46688748_-SINEAluName=AluJr4
ADediting_254406chr11_46688817_-SINEAluName=AluSx
ADediting_254407chr11_46688826_-SINEAluName=AluSx
ADediting_254408chr11_46688835_-SINEAluName=AluSx
ADediting_254409chr11_46688838_-SINEAluName=AluSx
ADediting_254410chr11_46688839_-SINEAluName=AluSx
ADediting_254411chr11_46688878_-SINEAluName=AluSx
ADediting_254412chr11_46688892_-SINEAluName=AluSx
ADediting_254413chr11_46688901_-SINEAluName=AluSx
ADediting_254414chr11_46688960_-SINEAluName=AluSx
ADediting_254415chr11_46688972_-SINEAluName=AluSx
ADediting_254416chr11_46688984_-SINEAluName=AluSx
ADediting_254417chr11_46689001_-SINEAluName=AluSx
ADediting_254418chr11_46689008_-SINEAluName=AluSx
ADediting_254419chr11_46689021_-SINEAluName=AluSx
ADediting_254420chr11_46689032_-SINEAluName=AluSx
ADediting_254421chr11_46689040_-SINEAluName=AluSx
ADediting_254422chr11_46689046_-SINEAluName=AluSx
ADediting_254423chr11_46689637_-SINEAluName=AluSx1
ADediting_254424chr11_46689689_-SINEAluName=AluSx1
ADediting_254425chr11_46689744_-SINEAluName=AluSx1
ADediting_254426chr11_46689745_-SINEAluName=AluSx1
ADediting_254427chr11_46689768_-SINEAluName=AluSx1
ADediting_254428chr11_46689785_-SINEAluName=AluSx1
ADediting_254429chr11_46689790_-SINEAluName=AluSx1
ADediting_254430chr11_46689811_-SINEAluName=AluSx1
ADediting_254431chr11_46689812_-SINEAluName=AluSx1
ADediting_254432chr11_46690120_-SINEAluName=AluY
ADediting_254433chr11_46690147_-SINEAluName=AluY
ADediting_254434chr11_46690187_-SINEAluName=AluY
ADediting_254435chr11_46690208_-SINEAluName=AluY
ADediting_254436chr11_46690209_-SINEAluName=AluY
ADediting_254437chr11_46690265_-SINEAluName=AluY
ADediting_254438chr11_46690275_-SINEAluName=AluY
ADediting_254439chr11_46690287_-SINEAluName=AluY
ADediting_254440chr11_46690324_-SINEAluName=AluY
ADediting_254441chr11_46690368_-SINEAluName=AluY
ADediting_254442chr11_46690487_-SINEAluName=FLAM_A
ADediting_254443chr11_46690505_-SINEAluName=FLAM_A
ADediting_254444chr11_46691347_-SINEAluName=AluSx
ADediting_254445chr11_46691423_-SINEAluName=AluSx
ADediting_254446chr11_46691576_-SINEAluName=AluSp
ADediting_254447chr11_46691645_-SINEAluName=AluSp
ADediting_254448chr11_46691694_-SINEAluName=AluSp
ADediting_254449chr11_46691791_-SINEAluName=AluSx
ADediting_254450chr11_46691860_-SINEAluName=AluSx
ADediting_254451chr11_46691863_-SINEAluName=AluSx
ADediting_254452chr11_46692750_-SINEAluName=AluSx3
ADediting_254453chr11_46692780_-SINEAluName=AluSx3
ADediting_254454chr11_46692825_-SINEAluName=AluSx3
ADediting_254455chr11_46693124_-SINEAluName=AluY
ADediting_254456chr11_46693544_-SINEAluName=AluJr
ADediting_254457chr11_46693557_-SINEAluName=AluJr
ADediting_254458chr11_46693629_-SINEAluName=AluJr
ADediting_1526935chr11_46681607_-SINEAluName=AluSx1
ADediting_1526936chr11_46681661_-SINEAluName=AluSx1
ADediting_1526937chr11_46683310_-SINEAluName=AluJb
ADediting_1526938chr11_46683334_-SINEAluName=AluJb
ADediting_1526939chr11_46683833_-SINEAluName=AluSp
ADediting_1526940chr11_46683834_-SINEAluName=AluSp
ADediting_1526941chr11_46683853_-SINEAluName=AluSp
ADediting_1526942chr11_46684950_-SINEAluName=AluSx
ADediting_1526943chr11_46685425_-SINEAluName=AluSp
ADediting_1526944chr11_46685433_-SINEAluName=AluSp
ADediting_1526945chr11_46685551_-SINEAluName=AluSp
ADediting_1526946chr11_46686077_-SINEAluName=AluSg
ADediting_1526947chr11_46686161_-SINEAluName=AluSg
ADediting_1526948chr11_46686234_-SINEAluName=AluSg
ADediting_1610004chr11_46688756_-SINEAluName=AluJr4

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RNA A-to-I editing events in the alternative splicing sites for ARHGAP1

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ARHGAP1

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.
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check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for ARHGAP1

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for ARHGAP1


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337757chr7_5495852_-ENSG00000175220.12ENST00000311956.9ARHGAP1-201hsa-miR-589-3pchr1146677309466773157mer-m84667730846677331140-18.01
ADediting_1391023chr8_140732605_-ENSG00000175220.12ENST00000311956.9ARHGAP1-201hsa-miR-151a-3pchr1146678013466780197mer-m84667801246678032145-20.82
ADediting_98289chr1_32086992_+ENSG00000175220.12ENST00000311956.9ARHGAP1-201hsa-miR-5585-3pchr1146677262466772687mer-m84667726146677285157-14.89

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ARHGAP1

check button - RNA A-to-I editing in mRNA.
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ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for ARHGAP1

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
TCXADediting_254281chr11_46682601_-0.2993576083819860.0852959955730680.0526386849826319-0.1585507017256357.83044580225825e-060.355909653743194
CERADediting_254287chr11_46682679_-0.1704704265984360.1125021754817170.07806996203240680.144319536838550.0001653829800479550.302833762410923
TCXADediting_254287chr11_46682679_-0.369172242985706-0.07384098280548820.00113530240403018-0.2632406041895243.41232952003175e-050.331514225247494
CERADediting_254295chr11_46683167_-0.003707834135214910.2355742562306670.0001223366797207470.3085421894633020.903042098624244-0.0100301643034765
CERADediting_254298chr11_46683242_-0.001440429828355780.2579119513388167.92646544685203e-060.3557157638202740.05332475669328640.158098986736398
CERADediting_254300chr11_46683270_-0.0004526207754443170.2828674484945668.12547170802842e-070.3899277390698920.0195009161876110.190561476950531
TCXADediting_254304chr11_46683726_-0.519132651739214-0.05304481174111080.000283406458053536-0.2923334486914254.67287637451759e-070.397683122543462
TCXADediting_254305chr11_46683743_-0.521531067229452-0.05274113790864440.000537078537997369-0.2793238191198312.18061523834281e-060.375576248862304
TCXADediting_254309chr11_46683781_-0.870145535528027-0.01345955687452250.00920519022096312-0.2119941642158088.27802692576897e-060.355024339278611
DLPFCADediting_254316chr11_46684844_-3.53598477047094e-050.2326117767693196.16333224124125e-080.3015263562378610.827075285071175-0.012457204140396
TCXADediting_254322chr11_46684939_-0.100196478473526-0.1347383842463770.00214380425236052-0.2487569729934412.47914026115666e-060.373659831625642
TCXADediting_254323chr11_46684940_-0.172937843866399-0.1118603557032460.0066272815472682-0.2207845173218471.48212966743321e-050.345583899233159
TCXADediting_254324chr11_46684944_-0.286828600728084-0.08753062142170090.0163034949391829-0.1958615122987727.23286810089946e-060.357169436799483
TCXADediting_254331chr11_46685005_-0.998673087555382-0.0001369320613910530.0154131390838549-0.1974980478967894.53765081336712e-070.398089312702806
TCXADediting_254334chr11_46685019_-0.467747216573590.0597365943956760.0862183604010623-0.1405651973286015.39752450781466e-060.361768659732165
DLPFCADediting_254338chr11_46685390_-0.6488130629636690.02596618299356910.0995153623077676-0.0937276957164043.982597816042e-140.41191537114459
TCXADediting_254343chr11_46685430_-0.5455934927186070.0497326036122790.0132287020848758-0.2018926170223311.12686025938652e-080.445347366956439
TCXADediting_254347chr11_46685482_-0.819568869230696-0.01877970667987540.0131249029620253-0.2021168407623416.75625985835278e-060.358246942078321
TCXADediting_254351chr11_46685520_-0.625832846598169-0.04013209157731770.0125968390617639-0.2032821756407112.07019980424097e-050.340027369821607
TCXADediting_254355chr11_46685559_-0.03610006522125030.1712873650856910.684060251268728-0.03349648750549741.33466785283086e-060.382798342512798
TCXADediting_254358chr11_46685789_-0.8958247318740330.01078088052444430.337499050635493-0.07884930108524414.00848377662881e-060.366372037993017
TCXADediting_254365chr11_46686034_-0.601614250627624-0.04296744569087020.0426438489522412-0.1657584959013887.59141236540289e-060.356402275635502
TCXADediting_254369chr11_46686080_-0.521715458432526-0.05271782083787130.00433230017193369-0.2316976791068342.95911706789034e-070.403942510764179
TCXADediting_254370chr11_46686081_-0.690568218457406-0.03276882236705290.00989062103744465-0.2100281887291537.68802627079444e-050.317116432402265
TCXADediting_254373chr11_46686096_-0.135740575074512-0.1223738084501176.89938720937477e-05-0.3190773465343646.17287661115738e-060.359668385458226
TCXADediting_254376chr11_46686151_-0.857110339443126-0.01482453686451260.00588246715045938-0.2238952616457462.49791756937063e-050.336857268510389
TCXADediting_254377chr11_46686155_-0.522492208925111-0.05261964337766290.000201987839671977-0.2989823402771536.57535775203667e-090.451670466628807
CERADediting_254379chr11_46686163_-0.04223037575123110.166085950913159.32579089039594e-050.3135834486361920.003592953999527590.236350748770658
TCXADediting_254379chr11_46686163_-0.751337593599186-0.02608665060688490.179053753710204-0.1102981839944590.0001519397380849090.304450847300073
CERADediting_254380chr11_46686164_-0.0179062024566370.1931021261011243.54018782773927e-050.3308775965823388.78419892616044e-050.31468270915883
TCXADediting_254380chr11_46686164_-0.948099321307819-0.005359684301067190.00908092063724775-0.2123643711427677.60615522149954e-080.421833684124221
TCXADediting_254386chr11_46686213_-0.9489611465514590.005270563810961160.0373817057364239-0.1701415968621862.62607227077459e-070.405557441598045
TCXADediting_254387chr11_46686218_-0.824803213016546-0.01822587047039530.0136713437043281-0.2009533856534667.68229824438772e-080.421706215866698
DLPFCADediting_254413chr11_46688901_-0.09845513697489240.09402125035401760.876318245320948-0.008875333504533255.60683811891264e-090.32338285144433
DLPFCADediting_254415chr11_46688972_-0.1393280556345250.08415264045684490.9765178097957030.001678564739660745.92946875598212e-140.409338858782057
DLPFCADediting_254424chr11_46689689_-0.3991513537779490.04805346587635360.364265571805634-0.05170370465804264.42459348515795e-120.379891144847381
DLPFCADediting_254425chr11_46689744_-0.104701755733740.0923264247524790.765409194756958-0.01701464787257183.16253851336094e-140.413397865639276
DLPFCADediting_254426chr11_46689745_-0.06658765877298250.1043265634573560.8061299984053420.0139948639521148.34245718500442e-130.391633596393547
DLPFCADediting_254428chr11_46689785_-0.3320853424876320.05526902733427140.9223846788627410.00555607199692271.68928560768932e-080.313546507652637
DLPFCADediting_254430chr11_46689811_-0.2200501811848870.06985161226593280.7867106042458390.01542958480329424.01344667953924e-080.305570322251027
DLPFCADediting_254433chr11_46690147_-0.01520796969644080.1377649437120650.5641641245223260.03287646799128363.2282091207397e-170.454627604109311
DLPFCADediting_254438chr11_46690275_-0.1225075202660470.08789749835411780.376478925299157-0.05040237150409011.94620865616372e-240.535837863946273
DLPFCADediting_254441chr11_46690368_-0.003008877077138030.167984208004440.4139931336520010.04655897219002483.49237720758836e-100.346692319911006

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC5.21122295763219e-260.5509645197591961.48655944132953e-230.5269956934805641.18704429144449e-300.591582696881962
AC2.03678377031109e-720.8542600746513378.8355747071482e-370.6907296098467052.94096082004591e-280.622858827103412
PCC1.50236202946209e-370.762246052423552.97659824876702e-280.6892360573743294.33740363593385e-070.355949173854449
CER1.03197662344616e-080.4463886608895719.34247365106054e-050.3135505443481582.9444042369078e-090.460868063068319
TCX4.16448523819829e-070.3992732660603870.320423617092647-0.08167370976519254.97990342250544e-240.707000752144774
FP8.82307489214941e-100.438973623751910.3792842841435090.06629453935040274.80912246365006e-180.589557821706965
IFG0.0004741427173573690.6469409004177460.03688223693492210.4194167457800330.0008533884503612590.624214130647297
PG0.08206071435272380.1278369918445210.928815309487837-0.006594780410946912.4293988665624e-170.56889407901358
STG4.33135908083077e-050.430651357447510.69488195218888-0.04342724390630771.83246283817530e-110.652069469846934

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Relation with AD stages for ARHGAP1

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
TCXADediting_254380chr11_46686164_-0.001365817086127590.307075648962723

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
TCX9.76679457939077e-050.369350457453814

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RelatedDrugs for ARHGAP1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ARHGAP1

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource
ARHGAP1C0036341Schizophrenia1PSYGENET