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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for ZNF470 |
 Gene summary |
| Gene information | Gene symbol | ZNF470 | Gene ID | 388566 |
| Gene name | zinc finger protein 470 | |
| Synonyms | CZF-1 | |
| Cytomap | 19q13.43 | |
| Type of gene | protein-coding | |
| Description | zinc finger protein 470chondrogenesis zinc finger protein 1 | |
| Modification date | 20200313 | |
| UniProtAcc | Q6ECI4, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for ZNF470 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_783723(56579325, +), ADediting_783726(56580754, +), ADediting_783744(56584786, +), ADediting_783746(56584839, +), ADediting_783747(56584866, +), ADediting_783748(56584869, +), ADediting_783749(56584895, +), ADediting_783750(56584896, +), ADediting_783751(56584918, +), ADediting_783753(56585131, +), ADediting_783755(56585186, +), ADediting_783756(56585212, +), ADediting_783757(56585217, +), ADediting_783758(56585220, +), ADediting_783759(56585222, +), ADediting_783760(56585237, +), ADediting_783761(56585324, +), ADediting_783772(56587262, +), ADediting_783773(56587279, +), ADediting_783775(56587374, +), ADediting_783776(56587377, +), ADediting_783777(56587391, +), ADediting_783778(56587454, +), ADediting_1559204(56579311, +), ADediting_1559206(56583506, +), ADediting_1631704(56575741, +), |
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RNA editing positional annotations for ZNF470 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_783723 | chr19_56579325_+ | UTR3 |
| ADediting_783726 | chr19_56580754_+ | UTR3 |
| ADediting_783744 | chr19_56584786_+ | intronic |
| ADediting_783746 | chr19_56584839_+ | intronic |
| ADediting_783747 | chr19_56584866_+ | intronic |
| ADediting_783748 | chr19_56584869_+ | intronic |
| ADediting_783749 | chr19_56584895_+ | intronic |
| ADediting_783750 | chr19_56584896_+ | intronic |
| ADediting_783751 | chr19_56584918_+ | intronic |
| ADediting_783753 | chr19_56585131_+ | intronic |
| ADediting_783755 | chr19_56585186_+ | intronic |
| ADediting_783756 | chr19_56585212_+ | intronic |
| ADediting_783757 | chr19_56585217_+ | intronic |
| ADediting_783758 | chr19_56585220_+ | intronic |
| ADediting_783759 | chr19_56585222_+ | intronic |
| ADediting_783760 | chr19_56585237_+ | intronic |
| ADediting_783761 | chr19_56585324_+ | intronic |
| ADediting_783772 | chr19_56587262_+ | intronic |
| ADediting_783773 | chr19_56587279_+ | intronic |
| ADediting_783775 | chr19_56587374_+ | intronic |
| ADediting_783776 | chr19_56587377_+ | intronic |
| ADediting_783777 | chr19_56587391_+ | intronic |
| ADediting_783778 | chr19_56587454_+ | intronic |
| ADediting_1559204 | chr19_56579311_+ | UTR3 |
| ADediting_1559206 | chr19_56583506_+ | intronic |
| ADediting_1631704 | chr19_56575741_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_783723 | chr19_56579325_+ | SINE | Alu | Name=AluJb |
| ADediting_783726 | chr19_56580754_+ | LINE | L2 | Name=L2 |
| ADediting_783744 | chr19_56584786_+ | SINE | Alu | Name=AluSx |
| ADediting_783746 | chr19_56584839_+ | SINE | Alu | Name=AluSx |
| ADediting_783747 | chr19_56584866_+ | SINE | Alu | Name=AluSx |
| ADediting_783748 | chr19_56584869_+ | SINE | Alu | Name=AluSx |
| ADediting_783749 | chr19_56584895_+ | SINE | Alu | Name=AluSx |
| ADediting_783750 | chr19_56584896_+ | SINE | Alu | Name=AluSx |
| ADediting_783751 | chr19_56584918_+ | SINE | Alu | Name=AluSx |
| ADediting_783753 | chr19_56585131_+ | SINE | Alu | Name=AluY |
| ADediting_783755 | chr19_56585186_+ | SINE | Alu | Name=AluY |
| ADediting_783756 | chr19_56585212_+ | SINE | Alu | Name=AluY |
| ADediting_783757 | chr19_56585217_+ | SINE | Alu | Name=AluY |
| ADediting_783758 | chr19_56585220_+ | SINE | Alu | Name=AluY |
| ADediting_783759 | chr19_56585222_+ | SINE | Alu | Name=AluY |
| ADediting_783760 | chr19_56585237_+ | SINE | Alu | Name=AluY |
| ADediting_783761 | chr19_56585324_+ | SINE | Alu | Name=AluY |
| ADediting_783772 | chr19_56587262_+ | SINE | Alu | Name=AluY |
| ADediting_783773 | chr19_56587279_+ | SINE | Alu | Name=AluY |
| ADediting_783775 | chr19_56587374_+ | SINE | Alu | Name=AluY |
| ADediting_783776 | chr19_56587377_+ | SINE | Alu | Name=AluY |
| ADediting_783777 | chr19_56587391_+ | SINE | Alu | Name=AluY |
| ADediting_783778 | chr19_56587454_+ | SINE | Alu | Name=AluY |
| ADediting_1559204 | chr19_56579311_+ | SINE | Alu | Name=AluJb |
| ADediting_1559206 | chr19_56583506_+ | SINE | Alu | Name=AluJr |
| ADediting_1631704 | chr19_56575741_+ | SINE | Alu | Name=FLAM_A |
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RNA A-to-I editing events in the alternative splicing sites for ZNF470 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ZNF470 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for ZNF470 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for ZNF470 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1559204 | chr19_56579311_+ | ENSG00000197016.12 | ENST00000330619.13 | ZNF470-201 | hsa-miR-646 | chr19 | 56579306 | 56579312 | 7mer-m8 | 56579294 | 56579313 | 144 | -19.09 |
| ADediting_1559204 | chr19_56579311_+ | ENSG00000197016.12 | ENST00000391709.4 | ZNF470-202 | hsa-miR-646 | chr19 | 56579306 | 56579312 | 7mer-m8 | 56579294 | 56579313 | 144 | -19.09 |
| ADediting_783723 | chr19_56579325_+ | ENSG00000197016.12 | ENST00000330619.13 | ZNF470-201 | hsa-miR-6747-3p | chr19 | 56579323 | 56579330 | 8mer-1a | 56579308 | 56579330 | 149 | -23.42 |
| ADediting_783723 | chr19_56579325_+ | ENSG00000197016.12 | ENST00000391709.4 | ZNF470-202 | hsa-miR-6747-3p | chr19 | 56579323 | 56579330 | 8mer-1a | 56579308 | 56579330 | 149 | -23.42 |
| ADediting_783726 | chr19_56580754_+ | ENSG00000197016.12 | ENST00000330619.13 | ZNF470-201 | hsa-miR-2115-5p | chr19 | 56580752 | 56580759 | 8mer-1a | 56580738 | 56580759 | 147 | -12.94 |
| ADediting_783726 | chr19_56580754_+ | ENSG00000197016.12 | ENST00000391709.4 | ZNF470-202 | hsa-miR-2115-5p | chr19 | 56580752 | 56580759 | 8mer-1a | 56580738 | 56580759 | 147 | -12.94 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1559204 | chr19_56579311_+ | ENSG00000197016.12 | ENST00000330619.13 | ZNF470-201 | hsa-miR-6869-5p | chr19 | 56579308 | 56579314 | 7mer-m8 | 56579292 | 56579315 | 148 | -16.95 |
| ADediting_1559204 | chr19_56579311_+ | ENSG00000197016.12 | ENST00000391709.4 | ZNF470-202 | hsa-miR-6869-5p | chr19 | 56579308 | 56579314 | 7mer-m8 | 56579292 | 56579315 | 148 | -16.95 |
| ADediting_783723 | chr19_56579325_+ | ENSG00000197016.12 | ENST00000330619.13 | ZNF470-201 | hsa-miR-3977 | chr19 | 56579321 | 56579327 | 7mer-m8 | 56579303 | 56579328 | 146 | -10.11 |
| ADediting_783723 | chr19_56579325_+ | ENSG00000197016.12 | ENST00000391709.4 | ZNF470-202 | hsa-miR-3977 | chr19 | 56579321 | 56579327 | 7mer-m8 | 56579303 | 56579328 | 146 | -10.11 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_783772 | chr19_56587262_+ | ENSG00000197016.12 | ENST00000601579.1 | ZNF470-205 | hsa-miR-4537 | chr19 | 56587260 | 56587267 | 8mer-1a | 56587245 | 56587267 | 151 | -25.93 |
| ADediting_783773 | chr19_56587279_+ | ENSG00000197016.12 | ENST00000601579.1 | ZNF470-205 | hsa-miR-10396a-5p | chr19 | 56587274 | 56587280 | 7mer-m8 | 56587263 | 56587281 | 154 | -28.31 |
| ADediting_783773 | chr19_56587279_+ | ENSG00000197016.12 | ENST00000601579.1 | ZNF470-205 | hsa-miR-10396b-5p | chr19 | 56587275 | 56587281 | 7mer-m8 | 56587263 | 56587282 | 159 | -26.89 |
| ADediting_783773 | chr19_56587279_+ | ENSG00000197016.12 | ENST00000601579.1 | ZNF470-205 | hsa-miR-1908-5p | chr19 | 56587275 | 56587281 | 7mer-m8 | 56587262 | 56587282 | 147 | -21.61 |
| ADediting_783773 | chr19_56587279_+ | ENSG00000197016.12 | ENST00000601579.1 | ZNF470-205 | hsa-miR-4508 | chr19 | 56587273 | 56587279 | 7mer-m8 | 56587264 | 56587280 | 143 | -22.23 |
| ADediting_783773 | chr19_56587279_+ | ENSG00000197016.12 | ENST00000601579.1 | ZNF470-205 | hsa-miR-663a | chr19 | 56587275 | 56587281 | 7mer-m8 | 56587259 | 56587282 | 152 | -28.86 |
| ADediting_783773 | chr19_56587279_+ | ENSG00000197016.12 | ENST00000601579.1 | ZNF470-205 | hsa-miR-6787-5p | chr19 | 56587275 | 56587281 | 7mer-m8 | 56587260 | 56587282 | 155 | -27.25 |
| ADediting_783773 | chr19_56587279_+ | ENSG00000197016.12 | ENST00000601579.1 | ZNF470-205 | hsa-miR-744-5p | chr19 | 56587274 | 56587280 | 7mer-m8 | 56587260 | 56587281 | 149 | -22.36 |
| ADediting_783778 | chr19_56587454_+ | ENSG00000197016.12 | ENST00000601579.1 | ZNF470-205 | hsa-miR-3189-3p | chr19 | 56587449 | 56587455 | 7mer-m8 | 56587437 | 56587456 | 149 | -22.19 |
| ADediting_783778 | chr19_56587454_+ | ENSG00000197016.12 | ENST00000601579.1 | ZNF470-205 | hsa-miR-6813-3p | chr19 | 56587450 | 56587456 | 7mer-m8 | 56587437 | 56587457 | 140 | -10.68 |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_783772 | chr19_56587262_+ | ENSG00000197016.12 | ENST00000601579.1 | ZNF470-205 | hsa-miR-3160-3p | chr19 | 56587260 | 56587267 | 8mer-1a | 56587246 | 56587267 | 150 | -20.6 |
| ADediting_783773 | chr19_56587279_+ | ENSG00000197016.12 | ENST00000601579.1 | ZNF470-205 | hsa-miR-3151-5p | chr19 | 56587274 | 56587280 | 7mer-m8 | 56587257 | 56587281 | 146 | -23.51 |
| ADediting_783773 | chr19_56587279_+ | ENSG00000197016.12 | ENST00000601579.1 | ZNF470-205 | hsa-miR-3689d | chr19 | 56587278 | 56587284 | 7mer-m8 | 56587265 | 56587285 | 146 | -17.88 |
| ADediting_783773 | chr19_56587279_+ | ENSG00000197016.12 | ENST00000601579.1 | ZNF470-205 | hsa-miR-6134 | chr19 | 56587277 | 56587283 | 7mer-m8 | 56587267 | 56587284 | 143 | -20.96 |
| ADediting_783773 | chr19_56587279_+ | ENSG00000197016.12 | ENST00000601579.1 | ZNF470-205 | hsa-miR-6851-5p | chr19 | 56587278 | 56587284 | 7mer-m8 | 56587263 | 56587285 | 154 | -22.1 |
| ADediting_783773 | chr19_56587279_+ | ENSG00000197016.12 | ENST00000601579.1 | ZNF470-205 | hsa-miR-92a-2-5p | chr19 | 56587275 | 56587281 | 7mer-m8 | 56587262 | 56587282 | 150 | -20.71 |
| ADediting_783776 | chr19_56587377_+ | ENSG00000197016.12 | ENST00000601579.1 | ZNF470-205 | hsa-miR-3675-3p | chr19 | 56587376 | 56587382 | 7mer-m8 | 56587362 | 56587383 | 145 | -12.58 |
| ADediting_783777 | chr19_56587391_+ | ENSG00000197016.12 | ENST00000601579.1 | ZNF470-205 | hsa-miR-216a-3p | chr19 | 56587390 | 56587396 | 7mer-m8 | 56587376 | 56587397 | 142 | -18.34 |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000197016.12 | ENST00000330619.13 | ZNF470-201 | hsa-miR-5688 | chr19 | 56582722 | 56582728 | 7mer-m8 | 56582708 | 56582729 | 149 | -13.49 |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000197016.12 | ENST00000391709.4 | ZNF470-202 | hsa-miR-5688 | chr19 | 56582722 | 56582728 | 7mer-m8 | 56582708 | 56582729 | 149 | -13.49 |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000197016.12 | ENST00000594953.1 | ZNF470-203 | hsa-miR-5688 | chr19 | 56582722 | 56582728 | 7mer-m8 | 56582708 | 56582729 | 149 | -13.49 |
| ADediting_1337758 | chr7_5495892_- | ENSG00000197016.12 | ENST00000330619.13 | ZNF470-201 | hsa-miR-589-5p | chr19 | 56580636 | 56580642 | 7mer-m8 | 56580623 | 56580643 | 158 | -26.56 |
| ADediting_1337758 | chr7_5495892_- | ENSG00000197016.12 | ENST00000391709.4 | ZNF470-202 | hsa-miR-589-5p | chr19 | 56580636 | 56580642 | 7mer-m8 | 56580623 | 56580643 | 158 | -26.56 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000197016.12 | ENST00000330619.13 | ZNF470-201 | hsa-miR-4477b | chr19 | 56581949 | 56581956 | 8mer-1a | 56581936 | 56581956 | 149 | -12.34 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000197016.12 | ENST00000391709.4 | ZNF470-202 | hsa-miR-4477b | chr19 | 56581949 | 56581956 | 8mer-1a | 56581936 | 56581956 | 149 | -12.34 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000197016.12 | ENST00000330619.13 | ZNF470-201 | hsa-miR-4477b | chr19 | 56579801 | 56579808 | 8mer-1a | 56579787 | 56579808 | 152 | -10.54 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000197016.12 | ENST00000330619.13 | ZNF470-201 | hsa-miR-4477b | chr19 | 56581871 | 56581878 | 8mer-1a | 56581859 | 56581878 | 157 | -16.02 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000197016.12 | ENST00000391709.4 | ZNF470-202 | hsa-miR-4477b | chr19 | 56579801 | 56579808 | 8mer-1a | 56579787 | 56579808 | 152 | -10.54 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000197016.12 | ENST00000391709.4 | ZNF470-202 | hsa-miR-4477b | chr19 | 56581871 | 56581878 | 8mer-1a | 56581859 | 56581878 | 157 | -16.02 |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000197016.12 | ENST00000330619.13 | ZNF470-201 | hsa-miR-381-3p | chr19 | 56579772 | 56579778 | 7mer-1a | 56579758 | 56579778 | 152 | -21.42 |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000197016.12 | ENST00000330619.13 | ZNF470-201 | hsa-miR-381-3p | chr19 | 56581632 | 56581638 | 7mer-m8 | 56581616 | 56581639 | 150 | -15.18 |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000197016.12 | ENST00000391709.4 | ZNF470-202 | hsa-miR-381-3p | chr19 | 56579772 | 56579778 | 7mer-1a | 56579758 | 56579778 | 152 | -21.42 |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000197016.12 | ENST00000391709.4 | ZNF470-202 | hsa-miR-381-3p | chr19 | 56581632 | 56581638 | 7mer-m8 | 56581616 | 56581639 | 150 | -15.18 |
| ADediting_286380 | chr11_79422188_- | ENSG00000197016.12 | ENST00000330619.13 | ZNF470-201 | hsa-miR-5579-3p | chr19 | 56582887 | 56582893 | 7mer-m8 | 56582875 | 56582893 | 156 | -16.8 |
| ADediting_286380 | chr11_79422188_- | ENSG00000197016.12 | ENST00000594953.1 | ZNF470-203 | hsa-miR-5579-3p | chr19 | 56582887 | 56582893 | 7mer-m8 | 56582875 | 56582894 | 156 | -16.91 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000197016.12 | ENST00000330619.13 | ZNF470-201 | hsa-miR-4775 | chr19 | 56581572 | 56581579 | 8mer-1a | 56581560 | 56581579 | 155 | -12.24 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000197016.12 | ENST00000330619.13 | ZNF470-201 | hsa-miR-4775 | chr19 | 56581674 | 56581681 | 8mer-1a | 56581660 | 56581681 | 162 | -9.91 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000197016.12 | ENST00000330619.13 | ZNF470-201 | hsa-miR-4775 | chr19 | 56582077 | 56582083 | 7mer-m8 | 56582063 | 56582084 | 146 | -8.4 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000197016.12 | ENST00000391709.4 | ZNF470-202 | hsa-miR-4775 | chr19 | 56581572 | 56581579 | 8mer-1a | 56581560 | 56581579 | 155 | -12.24 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000197016.12 | ENST00000391709.4 | ZNF470-202 | hsa-miR-4775 | chr19 | 56581674 | 56581681 | 8mer-1a | 56581660 | 56581681 | 162 | -9.91 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000197016.12 | ENST00000391709.4 | ZNF470-202 | hsa-miR-4775 | chr19 | 56582077 | 56582083 | 7mer-m8 | 56582063 | 56582084 | 146 | -8.4 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000197016.12 | ENST00000330619.13 | ZNF470-201 | hsa-miR-5585-3p | chr19 | 56581207 | 56581213 | 7mer-m8 | 56581195 | 56581214 | 142 | -13.69 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000197016.12 | ENST00000330619.13 | ZNF470-201 | hsa-miR-5585-3p | chr19 | 56581540 | 56581547 | 8mer-1a | 56581525 | 56581547 | 151 | -12.53 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000197016.12 | ENST00000391709.4 | ZNF470-202 | hsa-miR-5585-3p | chr19 | 56581207 | 56581213 | 7mer-m8 | 56581195 | 56581214 | 142 | -13.69 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000197016.12 | ENST00000391709.4 | ZNF470-202 | hsa-miR-5585-3p | chr19 | 56581540 | 56581547 | 8mer-1a | 56581525 | 56581547 | 151 | -12.53 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1556067 | chr19_40282625_- | ENSG00000197016.12 | ENST00000330619.13 | ZNF470-201 | hsa-miR-641 | chr19 | 56582383 | 56582390 | 8mer-1a | 56582364 | 56582390 | 143 | -12.13 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000197016.12 | ENST00000391709.4 | ZNF470-202 | hsa-miR-641 | chr19 | 56582383 | 56582390 | 8mer-1a | 56582364 | 56582390 | 143 | -12.13 |
| ADediting_1596844 | chr1_162342605_+ | ENSG00000197016.12 | ENST00000330619.13 | ZNF470-201 | hsa-miR-556-3p | chr19 | 56581510 | 56581517 | 8mer-1a | 56581495 | 56581517 | 147 | -8.72 |
| ADediting_1596844 | chr1_162342605_+ | ENSG00000197016.12 | ENST00000391709.4 | ZNF470-202 | hsa-miR-556-3p | chr19 | 56581510 | 56581517 | 8mer-1a | 56581495 | 56581517 | 147 | -8.72 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000197016.12 | ENST00000330619.13 | ZNF470-201 | hsa-miR-641 | chr19 | 56582383 | 56582390 | 8mer-1a | 56582364 | 56582390 | 143 | -12.13 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000197016.12 | ENST00000391709.4 | ZNF470-202 | hsa-miR-641 | chr19 | 56582383 | 56582390 | 8mer-1a | 56582364 | 56582390 | 143 | -12.13 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000197016.12 | ENST00000330619.13 | ZNF470-201 | hsa-miR-4775 | chr19 | 56581241 | 56581247 | 7mer-m8 | 56581228 | 56581248 | 143 | -4.51 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000197016.12 | ENST00000330619.13 | ZNF470-201 | hsa-miR-4775 | chr19 | 56581469 | 56581476 | 8mer-1a | 56581456 | 56581476 | 154 | -13.49 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000197016.12 | ENST00000391709.4 | ZNF470-202 | hsa-miR-4775 | chr19 | 56581241 | 56581247 | 7mer-m8 | 56581228 | 56581248 | 143 | -4.51 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000197016.12 | ENST00000391709.4 | ZNF470-202 | hsa-miR-4775 | chr19 | 56581469 | 56581476 | 8mer-1a | 56581456 | 56581476 | 154 | -13.49 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000197016.12 | ENST00000330619.13 | ZNF470-201 | hsa-miR-5585-3p | chr19 | 56581147 | 56581153 | 7mer-1a | 56581132 | 56581153 | 140 | -13.38 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000197016.12 | ENST00000391709.4 | ZNF470-202 | hsa-miR-5585-3p | chr19 | 56581147 | 56581153 | 7mer-1a | 56581132 | 56581153 | 140 | -13.38 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000197016.12 | ENST00000330619.13 | ZNF470-201 | hsa-miR-5585-3p | chr19 | 56581147 | 56581153 | 7mer-1a | 56581132 | 56581153 | 140 | -13.38 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000197016.12 | ENST00000391709.4 | ZNF470-202 | hsa-miR-5585-3p | chr19 | 56581147 | 56581153 | 7mer-1a | 56581132 | 56581153 | 140 | -13.38 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for ZNF470 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000330619.13 | protein_coding |  |  |
| ENST00000391709.4 | protein_coding |  |  |
| ENST00000601579.1 | lncRNA |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_1559204 | ENST00000330619.13 | chr19_56579311_+ | 3611 | -2053.50 | -2052.20 | -2057.80 |
| ADediting_783723 | ENST00000330619.13 | chr19_56579325_+ | 3625 | -2053.00 | -2052.20 | -2057.80 |
| ADediting_783726 | ENST00000330619.13 | chr19_56580754_+ | 5054 | -2056.80 | -2052.20 | -2057.80 |
| ADediting_1559204 | ENST00000391709.4 | chr19_56579311_+ | 3019 | -1768.80 | -1765.00 | -1775.40 |
| ADediting_783723 | ENST00000391709.4 | chr19_56579325_+ | 3033 | -1765.50 | -1765.00 | -1775.40 |
| ADediting_783726 | ENST00000391709.4 | chr19_56580754_+ | 4462 | -1770.80 | -1765.00 | -1775.40 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_783772 | ENST00000601579.1 | chr19_56587262_+ | 628 | -700.90 | -699.70 | -709.50 |
| ADediting_783773 | ENST00000601579.1 | chr19_56587279_+ | 645 | -703.20 | -699.70 | -709.50 |
| ADediting_783775 | ENST00000601579.1 | chr19_56587374_+ | 740 | -699.40 | -699.70 | -709.50 |
| ADediting_783776 | ENST00000601579.1 | chr19_56587377_+ | 743 | -699.40 | -699.70 | -709.50 |
| ADediting_783777 | ENST00000601579.1 | chr19_56587391_+ | 757 | -700.00 | -699.70 | -709.50 |
| ADediting_783778 | ENST00000601579.1 | chr19_56587454_+ | 820 | -705.10 | -699.70 | -709.50 |
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Relation with ADAR for ZNF470 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_783723 | chr19_56579325_+ | 0.00158416255126639 | 0.255751694576205 | 0.000115360296782963 | 0.309640513218671 | 0.678087499710557 | 0.0341665971680243 |
| TCX | ADediting_783726 | chr19_56580754_+ | 0.0294507275409636 | 0.177851914322504 | 0.645996321529746 | -0.0378070983802672 | 0.000118433508257333 | 0.309149250761572 |
| DLPFC | ADediting_783772 | chr19_56587262_+ | 0.0177159681658828 | 0.134622397587574 | 0.156047967663852 | 0.0807593769010803 | 1.66946465364757e-08 | 0.313653679388248 |
| DLPFC | ADediting_783773 | chr19_56587279_+ | 0.236043314333004 | 0.067495656417133 | 0.876705382319451 | 0.00884732953384998 | 9.47086122938194e-09 | 0.318751711270538 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 1.46989402979418e-11 | 0.371140493701303 | 1.82996391419922e-26 | 0.555198047253252 | 0.00168387000054782 | 0.177691413590087 |
| AC | 9.15139966445025e-49 | 0.762304773881857 | 2.58821219954121e-32 | 0.657350653864859 | 3.26091482788023e-22 | 0.561963603665113 |
| PCC | 1.88021607236527e-21 | 0.617368400275593 | 2.05404176549123e-23 | 0.640161230782794 | 0.0461129082752401 | 0.14449699523203 |
| FP | 3.81461948846573e-24 | 0.665649364124571 | 2.17241430868743e-29 | 0.717007238046445 | 0.0615587561001158 | 0.140416240803219 |
| IFG | 4.84651227906982e-05 | 0.720616472417505 | 0.00163664389968602 | 0.596808390426274 | 0.966645166773987 | -0.00881438444319047 |
| PG | 4.06680019313363e-55 | 0.857954291576169 | 1.21031234021631e-36 | 0.762548382122365 | 0.917867892087483 | 0.00761231795028978 |
| STG | 1.15118144786769e-15 | 0.738045978573007 | 9.0673485915069e-19 | 0.785481001203061 | 0.58882464610344 | 0.0598212484069218 |
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Relation with AD stages for ZNF470 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
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RelatedDrugs for ZNF470 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ZNF470 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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